Christina Sæten Fjeldbo
- Post doc; PhD
- +47 22 78 1446
Publications 2024
Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries
Clin Epigenetics, 16 (1), 56
DOI 10.1186/s13148-024-01669-z, PubMed 38643219
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
Theranostics, 14 (2), 714-737
DOI 10.7150/thno.88057, PubMed 38169509
An Immune Gene Expression Risk Score for Distant Metastases after Radiotherapy for Cervical Cancer
Clin Cancer Res, 30 (6), 1200-1207
DOI 10.1158/1078-0432.CCR-23-2085, PubMed 38180733
Spatial analysis of microRNA regulation at defined tumor hypoxia levels reveals biological traits of aggressive prostate cancer
J Pathol (in press)
DOI 10.1002/path.6344, PubMed 39329425
Publications 2023
Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
Radiother Oncol, 188, 109875
DOI 10.1016/j.radonc.2023.109875, PubMed 37640161
Publications 2022
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance
Nat Commun, 13 (1), 5818
DOI 10.1038/s41467-022-33544-x, PubMed 36207323
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630
A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients
Br J Cancer, 127 (2), 321-328
DOI 10.1038/s41416-022-01782-x, PubMed 35332267
Publications 2021
Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030499, PubMed 33525508
Publications 2020
Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity
EBioMedicine, 57, 102841
DOI 10.1016/j.ebiom.2020.102841, PubMed 32580139
MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
Cancer Res, 80 (18), 3993-4003
DOI 10.1158/0008-5472.CAN-20-0950, PubMed 32606004
Publications 2019
Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
Neoplasia, 21 (4), 353-362
DOI 10.1016/j.neo.2019.01.002, PubMed 30856376
Publications 2016
Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Clin Cancer Res, 22 (16), 4067-76
DOI 10.1158/1078-0432.CCR-15-2322, PubMed 27012812
Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients
PLoS One, 11 (5), e0156259
DOI 10.1371/journal.pone.0156259, PubMed 27244197
Publications 2015
Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer
Epigenetics, 10 (10), 970-80
DOI 10.1080/15592294.2015.1085140, PubMed 26291246
Publications 2013
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis
BMC Genomics, 14, 429
DOI 10.1186/1471-2164-14-429, PubMed 23805861
Gastrin-induced proliferation involves MEK partner 1 (MP1)
In Vitro Cell Dev Biol Anim, 49 (3), 162-9
DOI 10.1007/s11626-013-9588-2, PubMed 23408059
Publications 2011
Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats
Am J Physiol Gastrointest Liver Physiol, 302 (1), G21-33
DOI 10.1152/ajpgi.00197.2011, PubMed 21995960
Publications 2010
Functional studies on RNA-transfected cell microarrays
Methods Mol Biol, 629, 175-91
DOI 10.1007/978-1-60761-657-3_12, PubMed 20387150
Publications 2008
Functional studies on transfected cell microarray analysed by linear regression modelling
Nucleic Acids Res, 36 (15), e97
DOI 10.1093/nar/gkn428, PubMed 18628295