Finn Olav Levy
Position: Professor, group leader
Phone: +47 22840237
Email:
 

Author network for Finn Olav Levy by COREMINE medical


Publications 2017

Ahamed M, Vermeulen K, Schnekenburger M, Moltzau LR, Levy FO, Marton J, Froeyen M, Olberg DE, Diederich M, Bormans G (2017)
Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers
Lett. Drug Des. Discov., 14 (7), 787-797

Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur J Pharmacol, 812, 174-183
PubMed 28697992

Publications 2016

Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, Svindland A, Barbier O, Taskén KA (2016)
Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
Oncotarget, 7 (2), 1878-94
PubMed 26646591

Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang WZ, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Maelandsmo GM, Svindland A, Barbier O, Tasken KA (2016)
Low beta(2)-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
Oncotarget, 7 (2), 1878-1894

Eikemo H, Moltzau LR, Hussain RI, Nguyen CH, Qvigstad E, Levy FO, Skomedal T, Osnes JB (2016)
CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes
Biochem Biophys Res Commun, 471 (1), 219-25
PubMed 26809094

Eikemo H, Moltzau LR, Nguyen CH, Levy FO, Skomedal T, Osnes JB (2016)
CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes
Biochem Biophys Res Commun, 477 (1), 14-9
PubMed 27237977

Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2016)
Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats
Nucl Med Biol, 43 (8), 478-89
PubMed 27236283

Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO, Hobbs AJ (2016)
Functional pharmacological characterization of SER100 in cardiovascular health and disease
Br J Pharmacol, 173 (23), 3386-3401
PubMed 27667485

Publications 2015

Andressen KW, Manfra O, Brevik CH, Ulsund AH, Vanhoenacker P, Levy FO, Krobert KA (2015)
The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors
Br J Pharmacol, 172 (15), 3846-60
PubMed 25884989

Impellizzeri AA, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S (2015)
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
Front Behav Neurosci, 9, 92
PubMed 26005408

Manfra O, Van Craenenbroeck K, Skieterska K, Frimurer T, Schwartz TW, Levy FO, Andressen KW (2015)
Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
ACS Chem Neurosci, 6 (7), 1206-18
PubMed 25706089

Olberg DE, Hausner SH, Bauer N, Klaveness J, Indrevoll B, Andressen KW, Dahl M, Levy FO, Sutcliffe JL, Haraldsen I (2015)
Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats
MedChemComm, 6 (4), 708-714

Ørstavik Ø, Manfra O, Andressen KW, Andersen GØ, Skomedal T, Osnes JB, Levy FO, Krobert KA (2015)
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium
PLoS One, 10 (3), e0115547
PubMed 25738589

Publications 2014

Brudeli B, Navaratnarajah M, Andressen KW, Manfra O, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2014)
Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists
Bioorg Med Chem Lett, 24 (18), 4598-4602
PubMed 25149506

Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G (2014)
Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
FASEB J, 28 (5), 2293-305
PubMed 24500924

Melsom CB, Hussain RI, Ørstavik Ø, Aronsen JM, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2014)
Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
Naunyn Schmiedebergs Arch Pharmacol, 387 (12), 1177-86
PubMed 25216690

Melsom CB, Ørstavik Ø, Osnes JB, Skomedal T, Levy FO, Krobert KA (2014)
Gi proteins regulate adenylyl cyclase activity independent of receptor activation
PLoS One, 9 (9), e106608
PubMed 25203113

Moltzau LR, Aronsen JM, Meier S, Skogestad J, Ørstavik Ø, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
J Pharmacol Exp Ther, 350 (3), 681-90
PubMed 25022512

Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
PubMed 24424715

Olberg DE, Andressen KW, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2014)
Synthesis and in vitro evaluation of small-molecule [18F] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression
Bioorg Med Chem Lett, 24 (7), 1846-50
PubMed 24613701

Orstavik O, Ata SH, Riise J, Dahl CP, Andersen GØ, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2014)
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
Br J Pharmacol, 171 (23), 5169-81
PubMed 24547784

Ytrehus K, Larsen T, Christensen G, Stensløkken KO, Levy FO (2014)
In memory of Guro Valen (1960-2014)
J Mol Cell Cardiol, 79, 254-5
PubMed 25490150

Publications 2013

Bach T, Bergholtz S, Riise J, Qvigstad E, Skomedal T, Osnes JB, Levy FO (2013)
Identification of small molecule NPR-B antagonists by high throughput screening--potential use in heart failure
Naunyn Schmiedebergs Arch Pharmacol, 387 (1), 5-14
PubMed 24297249

Brudeli B, Andressen KW, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2013)
Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists
Bioorg Med Chem, 21 (22), 7134-45
PubMed 24113240

Brudeli B, Moltzau LR, Nguyen CH, Andressen KW, Nilsen NO, Levy FO, Klaveness J (2013)
Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
Eur J Med Chem, 64, 629-37
PubMed 23711770

Gellynck E, Heyninck K, Andressen KW, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2013)
The serotonin 5-HT7 receptors: two decades of research
Exp Brain Res, 230 (4), 555-68
PubMed 24042216

Gravning J, Ahmed MS, Qvigstad E, Krobert K, Edvardsen T, Moe IT, Hagelin EM, Sagave J, Valen G, Levy FO, Osnes JB, Skomedal T, Attramadal H (2013)
Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes
Mol Pharmacol, 84 (3), 372-83
PubMed 23778361

Levay M, Krobert KA, Wittig K, Voigt N, Bermudez M, Wolber G, Dobrev D, Levy FO, Wieland T (2013)
NSC23766, a widely used inhibitor of Rac1 activation, additionally acts as a competitive antagonist at muscarinic acetylcholine receptors
J Pharmacol Exp Ther, 347 (1), 69-79
PubMed 23887096

Levy FO (2013)
Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility
Naunyn Schmiedebergs Arch Pharmacol, 386 (8), 665-70
PubMed 23649864

Molenaar P, Christ T, Hussain RI, Engel A, Berk E, Gillette KT, Chen L, Galindo-Tovar A, Krobert KA, Ravens U, Levy FO, Kaumann AJ (2013)
PDE3, but not PDE4, reduces β₁ - and β₂-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients
Br J Pharmacol, 169 (3), 528-38
PubMed 23489141

Moltzau LR, Aronsen JM, Meier S, Nguyen CH, Hougen K, Ørstavik Ø, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br J Pharmacol, 170 (2), 366-79
PubMed 23808942

Publications 2012

Bilbija D, Haugen F, Sagave J, Baysa A, Bastani N, Levy FO, Sirsjö A, Blomhoff R, Valen G (2012)
Retinoic acid signalling is activated in the postischemic heart and may influence remodelling
PLoS One, 7 (9), e44740
PubMed 23028599

Brattelid T, Qvigstad E, Moltzau LR, Bekkevold SV, Sandnes DL, Birkeland JA, Skomedal T, Osnes JB, Sjaastad I, Levy FO (2012)
The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure
PLoS One, 7 (9), e45489
PubMed 23029047

Gellynck E, Andressen KW, Lintermans B, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2012)
Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT₇a receptor
FEBS J, 279 (11), 1994-2003
PubMed 22448645

Hussain RI, Aronsen JM, Afzal F, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
J Mol Cell Cardiol, 56, 129-38
PubMed 23220156

Riise J, Nguyen CH, Hussain RI, Dahl CP, Ege MS, Osnes JB, Skomedal T, Sandnes DL, Levy FO, Krobert KA (2012)
Prostanoid-mediated inotropic responses are attenuated in failing human and rat ventricular myocardium
Eur J Pharmacol, 686 (1-3), 66-73
PubMed 22546232

Riise J, Ørstavik Ø, Qvigstad E, Dahl CP, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
Prostaglandin E1 facilitates inotropic effects of 5-HT4 serotonin receptors and β-adrenoceptors in failing human heart
Basic Res Cardiol, 107 (5), 295
PubMed 22923058

von Lueder TG, Gravning J, How OJ, Vinge LE, Ahmed MS, Krobert KA, Levy FO, Larsen TS, Smiseth OA, Aasum E, Attramadal H (2012)
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am J Physiol Heart Circ Physiol, 303 (1), H66-74
PubMed 22542621

Publications 2011

Afzal F, Aronsen JM, Moltzau LR, Sjaastad I, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2011)
Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
Br J Pharmacol, 162 (1), 54-71
PubMed 21133887

Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
PubMed 21901315

Berrade L, Aisa B, Ramirez MJ, Galiano S, Guccione S, Moltzau LR, Levy FO, Nicoletti F, Battaglia G, Molinaro G, Aldana I, Monge A, Perez-Silanes S (2011)
Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of action
J Med Chem, 54 (8), 3086-90
PubMed 21469694

Brattelid T, Levy FO (2011)
Quantification of GPCR mRNA using real-time RT-PCR
Methods Mol Biol, 746, 165-93
PubMed 21607857

Hussain RI, Afzal F, Mørk HK, Aronsen JM, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2011)
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
Br J Pharmacol, 162 (4), 908-16
PubMed 21039419

Publications 2010

Brattelid T, Winer LH, Levy FO, Liestøl K, Sejersted OM, Andersson KB (2010)
Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies
BMC Mol Biol, 11, 22
PubMed 20331858

Brudeli B, Moltzau LR, Andressen KW, Krobert KA, Klaveness J, Levy FO (2010)
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
Bioorg Med Chem, 18 (24), 8600-13
PubMed 21075638

Publications 2009

Hussain RI, Qvigstad E, Birkeland JA, Eikemo H, Glende A, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2009)
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation
Br J Pharmacol, 156 (4), 575-86
PubMed 19159405

Kjekshus JK, Torp-Pedersen C, Gullestad L, Køber L, Edvardsen T, Olsen IC, Sjaastad I, Qvigstad E, Skomedal T, Osnes JB, Levy FO (2009)
Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure
Eur J Heart Fail, 11 (8), 771-8
PubMed 19567409

Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB (2009)
Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
Cardiovasc Res, 85 (4), 763-72
PubMed 19900965

Publications 2008

Afzal F, Andressen KW, Mørk HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
Br J Pharmacol, 155 (7), 1005-14
PubMed 18846035

Eikemo H, Skomedal T, Levy FO, Osnes JB (2008)
Calculating reaction rate constants and estimating the efficacy of selective enzyme inhibitors
Anal Biochem, 383 (2), 323-5
PubMed 18831958

Gellynck E, Laenen K, Andressen KW, Lintermans B, De Martelaere K, Matthys A, Levy FO, Haegeman G, Vanhoenacker P, Van Craenenbroeck K (2008)
Cloning, genomic organization and functionality of 5-HT(7) receptor splice variants from mouse brain
Gene, 426 (1-2), 23-31
PubMed 18793707

Kloster MM, Hafte TT, Moltzau LR, Naderi EH, Dahle MK, Skålhegg BS, Gaudernack G, Levy FO, Naderi S, Blomhoff HK (2008)
EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase
Cell Signal, 20 (6), 1169-78
PubMed 18406106

Larsen KO, Lygren B, Sjaastad I, Krobert KA, Arnkvaern K, Florholmen G, Larsen AK, Levy FO, Taskén K, Skjønsberg OH, Christensen G (2008)
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A
Cardiovasc Res, 80 (1), 47-54
PubMed 18599478

Levy FO, Qvigstad E, Krobert KA, Skomedal T, Osnes JB (2008)
Effects of serotonin in failing cardiac ventricle: signalling mechanisms and potential therapeutic implications
Neuropharmacology, 55 (6), 1066-71
PubMed 18675829

Ngai J, Methi T, Andressen KW, Levy FO, Torgersen KM, Vang T, Wettschureck N, Taskén K (2008)
The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway
Eur J Immunol, 38 (11), 3208-18
PubMed 18991294

Ramberg H, Eide T, Krobert KA, Levy FO, Dizeyi N, Bjartell AS, Abrahamsson PA, Taskén KA (2008)
Hormonal regulation of beta2-adrenergic receptor level in prostate cancer
Prostate, 68 (10), 1133-42
PubMed 18454446

Riise J, Nguyen CH, Qvigstad E, Sandnes DL, Osnes JB, Skomedal T, Levy FO, Krobert KA (2008)
Prostanoid F receptors elicit an inotropic effect in rat left ventricle by enhancing myosin light chain phosphorylation
Cardiovasc Res, 80 (3), 407-15
PubMed 18703533

Publications 2007

Birkeland JA, Swift F, Tovsrud N, Enger U, Lunde PK, Qvigstad E, Levy FO, Sejersted OM, Sjaastad I (2007)
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Am J Physiol Heart Circ Physiol, 293 (4), H2367-76
PubMed 17660386

Brattelid T, Qvigstad E, Birkeland JA, Swift F, Bekkevold SV, Krobert KA, Sejersted OM, Skomedal T, Osnes JB, Levy FO, Sjaastad I (2007)
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle
J Mol Cell Cardiol, 43 (6), 767-79
PubMed 17936780

Brattelid T, Tveit K, Birkeland JA, Sjaastad I, Qvigstad E, Krobert KA, Hussain RI, Skomedal T, Osnes JB, Levy FO (2007)
Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure--a quantitative RT-PCR study and the question of normalisation
Basic Res Cardiol, 102 (3), 198-208
PubMed 17370034

Schulte G, Levy FO (2007)
Novel aspects of G-protein-coupled receptor signalling--different ways to achieve specificity
Acta Physiol (Oxf), 190 (1), 33-8
PubMed 17428230

Vinge LE, Andressen KW, Attramadal T, Andersen GØ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol Pharmacol, 72 (3), 582-91
PubMed 17573483

Publications 2006

Birkeland JA, Sjaastad I, Brattelid T, Qvigstad E, Moberg ER, Krobert KA, Bjørnerheim R, Skomedal T, Sejersted OM, Osnes JB, Levy FO (2006)
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
Br J Pharmacol, 150 (2), 143-52
PubMed 17160012

Kaumann AJ, Levy FO (2006)
5-hydroxytryptamine receptors in the human cardiovascular system
Pharmacol Ther, 111 (3), 674-706
PubMed 16960982

Kaumann AJ, Levy FO (2006)
Fading of 5-HT4 receptor-mediated inotropic responses to 5-hydroxytryptamine is caused by phosphodiesterase activity in porcine atrium
Br J Pharmacol, 147 (2), 128-30
PubMed 16331292

Krobert KA, Andressen KW, Levy FO (2006)
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor
Eur J Pharmacol, 532 (1-2), 1-10
PubMed 16487959

Norum JH, Dawood H, Mattingly RR, Sandnes D, Levy FO (2006)
Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells
FEBS Lett, 581 (1), 15-20
PubMed 17174312

Publications 2005

Andressen KW, Norum JH, Levy FO, Krobert KA (2005)
Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression
Mol Pharmacol, 69 (1), 207-15
PubMed 16189297

Krobert KA, Brattelid T, Levy FO, Kaumann AJ (2005)
Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants
Naunyn Schmiedebergs Arch Pharmacol, 371 (6), 473-9
PubMed 16012870

Norum JH, Méthi T, Mattingly RR, Levy FO (2005)
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells
FEBS J, 272 (9), 2304-16
PubMed 15853814

Qvigstad E, Brattelid T, Sjaastad I, Andressen KW, Krobert KA, Birkeland JA, Sejersted OM, Kaumann AJ, Skomedal T, Osnes JB, Levy FO (2005)
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
Cardiovasc Res, 65 (4), 869-78
PubMed 15721867

Qvigstad E, Sjaastad I, Brattelid T, Nunn C, Swift F, Birkeland JA, Krobert KA, Andersen GØ, Sejersted OM, Osnes JB, Levy FO, Skomedal T (2005)
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
Circ Res, 97 (3), 268-76
PubMed 16002744

Publications 2004

Brattelid T, Kvingedal AM, Krobert KA, Andressen KW, Bach T, Hystad ME, Kaumann AJ, Levy FO (2004)
Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)
Naunyn Schmiedebergs Arch Pharmacol, 369 (6), 616-28
PubMed 15118808

Brattelid T, Qvigstad E, Lynham JA, Molenaar P, Aass H, Geiran O, Skomedal T, Osnes JB, Levy FO, Kaumann AJ (2004)
Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure
Naunyn Schmiedebergs Arch Pharmacol, 370 (3), 157-66
PubMed 15365689

Skulberg KR, Skyberg K, Kruse K, Eduard W, Djupesland P, Levy F, Kjuus H (2004)
The effect of cleaning on dust and the health of office workers: an intervention study
Epidemiology, 15 (1), 71-8
PubMed 14712149

Verheggen R, Meier A, Werner I, Wienekamp A, Kruschat T, Brattelid T, Levy FO, Kaumann A (2004)
Functional 5-HT receptors in human occipital artery
Naunyn Schmiedebergs Arch Pharmacol, 369 (4), 391-401
PubMed 15007537

Øie E, Vinge LE, Andersen GØ, Yndestad A, Krobert KA, Sandberg C, Ahmed MS, Haug T, Levy FO, Skomedal T, Attramadal H (2004)
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
PubMed 15623431

Publications 2003

Andersen GØ, Skomedal T, Enger M, Fidjeland A, Brattelid T, Levy FO, Osnes JB (2003)
Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter
Am J Physiol Heart Circ Physiol, 286 (4), H1354-60
PubMed 14630635

Bruheim S, Krobert KA, Andressen KW, Levy FO (2003)
Unaltered agonist potency upon inducible 5-HT7(a) but not 5-HT4(b) receptor expression indicates agonist-independent association of 5-HT7(a) receptor and Gs
Receptors Channels, 9 (2), 107-16
PubMed 12916471

Publications 2002

Krobert KA, Levy FO (2002)
The human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effects
Br J Pharmacol, 135 (6), 1563-71
PubMed 11906971

Norum JH, Hart K, Levy FO (2002)
Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a)
J Biol Chem, 278 (5), 3098-104
PubMed 12446729

Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E (2002)
Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae
J Cell Sci, 115 (Pt 6), 1331-40
PubMed 11884532

Publications 2001

Bach T, Syversveen T, Kvingedal AM, Krobert KA, Brattelid T, Kaumann AJ, Levy FO (2001)
5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle
Naunyn Schmiedebergs Arch Pharmacol, 363 (2), 146-60
PubMed 11218067

Krobert KA, Bach T, Syversveen T, Kvingedal AM, Levy FO (2001)
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution
Naunyn Schmiedebergs Arch Pharmacol, 363 (6), 620-32
PubMed 11414657

Vang T, Torgersen KM, Sundvold V, Saxena M, Levy FO, Skålhegg BS, Hansson V, Mustelin T, Taskén K (2001)
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
J Exp Med, 193 (4), 497-507
PubMed 11181701

Publications 2000

Bourdon DM, Camden JM, Landon LA, Levy FO, Turner JT (2000)
Identification of the adenylyl cyclase-activating 5-hydroxytryptamine receptor subtypes expressed in the rat submandibular gland
Br J Pharmacol, 130 (1), 104-8
PubMed 10781004

Munthe E, Rian E, Holien T, Rasmussen A, Levy FO, Aasheim H (2000)
Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
FEBS Lett, 466 (1), 169-74
PubMed 10648835

Publications 1999

Myklebust JH, Josefsen D, Blomhoff HK, Levy FO, Naderi S, Reed JC, Smeland EB (1999)
Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
J Cell Physiol, 180 (1), 71-80
PubMed 10362019

Publications 1998

Ringerike T, Stang E, Johannessen LE, Sandnes D, Levy FO, Madshus IH (1998)
High-affinity binding of epidermal growth factor (EGF) to EGF receptor is disrupted by overexpression of mutant dynamin (K44A)
J Biol Chem, 273 (27), 16639-42
PubMed 9642213

Skålhegg BS, Johansen AK, Levy FO, Andersson KB, Aandahl EM, Blomhoff HK, Hansson V, Taskén K (1998)
Isozymes of cyclic AMP-dependent protein kinases (PKA) in human lymphoid cell lines: levels of endogenous cAMP influence levels of PKA subunits and growth in lymphoid cell lines
J Cell Physiol, 177 (1), 85-93
PubMed 9731748

Vang T, Taskén K, Skålhegg BS, Hansson V, Levy FO (1998)
Kinetic properties of the C-terminal Src kinase, p50csk
Biochim Biophys Acta, 1384 (2), 285-93
PubMed 9659389

Publications 1997

Rasmussen AM, Horejsí V, Levy FO, Blomhoff HK, Smeland EB, Beiske K, Michaelsen TE, Gaudernack G, Funderud S (1997)
CDw78--a determinant on a major histocompatibility complex class II subpopulation that can be induced to associate with the cytoskeleton
Eur J Immunol, 27 (12), 3206-13
PubMed 9464807

Taskén K, Skålhegg BS, Taskén KA, Solberg R, Knutsen HK, Levy FO, Sandberg M, Orstavik S, Larsen T, Johansen AK, Vang T, Schrader HP, Reinton NT, Torgersen KM, Hansson V, Jahnsen T (1997)
Structure, function, and regulation of human cAMP-dependent protein kinases
Adv Second Messenger Phosphoprotein Res, 31, 191-204
PubMed 9344252

Torgersen KM, Vaage JT, Levy FO, Hansson V, Rolstad B, Taskén K (1997)
Selective activation of cAMP-dependent protein kinase type I inhibits rat natural killer cell cytotoxicity
J Biol Chem, 272 (9), 5495-500
PubMed 9038153

Publications 1996

Levy FO, Rasmussen AM, Taskén K, Skålhegg BS, Huitfeldt HS, Funderud S, Smeland EB, Hansson V (1996)
Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation
Eur J Immunol, 26 (6), 1290-6
PubMed 8647207

Levy FO, Taskén K, Hansson V (1996)
Report on the 9th European Workshop on the Molecular and Cellular Endocrinology of the Testis
Mol Cell Endocrinol, 122 (1), 1-13
PubMed 8898343

Publications 1995

Eikvar L, Levy FO, Attramadal H, Hansson V (1995)
Modulation of gonadotropic and purinergic responsiveness by islet activating protein in sertoli cells from immature rats
J Steroid Biochem Mol Biol, 52 (5), 431-6
PubMed 7748808

Publications 1994

Birnbaumer L, Levy FO, Zhu X, Kaumann AJ (1994)
Studies on the intrinsic activity (efficacy) of human adrenergic receptors. Co-expression of beta 1 and beta 2 reveals a lower efficacy for the beta 1 receptor
Tex Heart Inst J, 21 (1), 16-21
PubMed 8180506

Levy FO, Holtgreve-Grez H, Taskén K, Solberg R, Ried T, Gudermann T (1994)
Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15
Genomics, 22 (3), 637-40
PubMed 8001977

Publications 1993

Gudermann T, Levy FO, Birnbaumer M, Birnbaumer L, Kaumann AJ (1993)
Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor
Mol Pharmacol, 43 (3), 412-8
PubMed 8450834

Levy FO, Zhu X, Kaumann AJ, Birnbaumer L (1993)
Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors
Proc Natl Acad Sci U S A, 90 (22), 10798-802
PubMed 8248173

Publications 1992

Gudermann T, Nichols C, Levy FO, Birnbaumer M, Birnbaumer L (1992)
Ca2+ mobilization by the LH receptor expressed in Xenopus oocytes independent of 3',5'-cyclic adenosine monophosphate formation: evidence for parallel activation of two signaling pathways
Mol Endocrinol, 6 (2), 272-8
PubMed 1314958

Levy FO, Gudermann T, Birnbaumer M, Kaumann AJ, Birnbaumer L (1992)
Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase
FEBS Lett, 296 (2), 201-6
PubMed 1733778

Levy FO, Gudermann T, Perez-Reyes E, Birnbaumer M, Kaumann AJ, Birnbaumer L (1992)
Molecular cloning of a human serotonin receptor (S12) with a pharmacological profile resembling that of the 5-HT1D subtype
J Biol Chem, 267 (11), 7553-62
PubMed 1559993

Publications 1991

Eskild W, Ree AH, Levy FO, Jahnsen T, Hansson V (1991)
Cellular localization of mRNAs for retinoic acid receptor-alpha, cellular retinol-binding protein, and cellular retinoic acid-binding protein in rat testis: evidence for germ cell-specific mRNAs
Biol Reprod, 44 (1), 53-61
PubMed 1849753

Publications 1989

Levy FO, Ree AH, Eikvar L, Govindan MV, Jahnsen T, Hansson V (1989)
Glucocorticoid receptors and glucocorticoid effects in rat Sertoli cells
Endocrinology, 124 (1), 430-6
PubMed 2909375

Ree AH, Landmark BF, Eskild W, Levy FO, Lahooti H, Jahnsen T, Aakvaag A, Hansson V (1989)
Autologous down-regulation of messenger ribonucleic acid and protein levels for estrogen receptors in MCF-7 cells: an inverse correlation to progesterone receptor levels
Endocrinology, 124 (5), 2577-83
PubMed 2651098

Publications 1988

Erichsen A, Levy FO, Golf S, Hansson V (1988)
A transplantable rat Leydig cell tumor--5. Cellular localization of beta-adrenergic and prostaglandin receptors and their effects on testosterone production
J Steroid Biochem, 31 (1), 41-8
PubMed 2840532

Levy FO, Oyen O, Sandberg M, Taskén K, Eskild W, Hansson V, Jahnsen T (1988)
Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis
Mol Endocrinol, 2 (12), 1364-73
PubMed 2851102

Oyen O, Sandberg M, Eskild W, Levy FO, Knutsen G, Beebe S, Hansson V, Jahnsen T (1988)
Differential regulation of messenger ribonucleic acids for specific subunits of cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinase by cAMP in rat Sertoli cells
Endocrinology, 122 (6), 2658-66
PubMed 2836170

Oyen O, Sandberg M, Levy FO, Taskén K, Beebe S, Hansson V, Jahnsen T (1988)
Molecular cloning and cell-specific expression of newly discovered subunits of cAMP-dependent protein kinases. Implications for different cellular responses to cAMP
APMIS Suppl, 2, 238-50
PubMed 2846017

Sandberg M, Levy FO, Oyen O, Hansson V, Jahnsen T (1988)
Molecular cloning, cDNA structure and deduced amino acid sequence for the hormone-induced regulatory subunit (RII beta) of cAMP-dependent protein kinase from rat ovarian granulosa cells
Biochem Biophys Res Commun, 154 (2), 705-11
PubMed 3401231

Publications 1987

Haugen TB, Levy FO, Hansson V, Fritzson P (1987)
Effects of cryptorchidism and orchidopexy on deoxyribonucleoside-activated nucleotidase (DAN) in the rat testis
Int J Biochem, 19 (11), 1023-7
PubMed 2892698

Publications 1985

Eikvar L, Levy FO, Attramadal H, Jutte NH, Frøysa A, Tvermyr SM, Hansson V (1985)
Glucagon-stimulated cyclic AMP production and formation of estradiol in Sertoli cell cultures from immature rats
Mol Cell Endocrinol, 39 (2), 107-13
PubMed 2984057

Eikvar L, Levy FO, Jutte NH, Cervenka J, Yoganathan T, Hansson V (1985)
Effects of adenosine analogs on glucagon-stimulated adenosine 3',5'-monophosphate formation in Sertoli cell cultures from immature rats
Endocrinology, 117 (2), 488-91
PubMed 2990852

Jutte NH, Eikvar L, Levy FO, Hansson V (1985)
Metabolism of palmitate in cultured rat Sertoli cells
J Reprod Fertil, 73 (2), 497-503
PubMed 4039365

Levy FO, Eikvar L, Frøysa A, Hansson V (1985)
"Differential displacement"--a simple method to study receptors for 1,25-dihydroxyvitamin D3 in the presence of contaminating serum vitamin D binding protein
Biochem Biophys Res Commun, 130 (3), 1020-6
PubMed 2992493

Levy FO, Eikvar L, Jutte NH, Cervenka J, Yoganathan T, Hansson V (1985)
Appearance of the rat testicular receptor for calcitriol (1,25-dihydroxyvitamin D3) during development
J Steroid Biochem, 23 (1), 51-6
PubMed 2991662

Levy FO, Eikvar L, Jutte NH, Frøysa A, Tvermyr SM, Hansson V (1985)
Properties and compartmentalization of the testicular receptor for 1,25-dihydroxyvitamin D3
J Steroid Biochem, 22 (4), 453-60
PubMed 2987614