Our research is focused on understanding the genomics of breast cancer, and in particular the role of TP53 and associated molecular networks. TP53 is a key regulator of many critical cellular processes and the gene is affected by mutation in breast cancer subtypes with poor prognosis. By integrating cancer genome profiling with single gene analysis in large series of patient samples, we aim to search for diagnostic, prognostic and predictive biomarkers of breast cancer.
Current projects and funding sources:
- Elucidating the TP53 network in breast cancer (Helse Sør-Øst)
- Breast Cancer Somatic Genetics Study (BASIS; EU FP7)
Contact information:Department of Genetics, Institute for Cancer Research, Oslo University Hospital - Radiumhospitalet, Montebello, 0310 Oslo, Norway. Phone: +47 22 78 13 76, Fax: +47 22 78 13 95, Switchboard: +47 22 93 40 00. Email: firstname.lastname@example.org