Semiconductor nanoparticles, so-called quantum dots, are being used for fluorescent imaging of cancer cells in vitro and in animals in vivo. We introduce the concept of using these nanoparticles as photosensitizers. Real-time monitoring using Electric Cell-substrate Impedance Sensing (ECIS) of cancer cell responses to photodynamic toxicity caused by quantum dots are studied in this project.
Espeland K, Kleinauskas A, Juzenas P, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q(2023) Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells from Patients with Crohn's Disease Int J Mol Sci, 24(5) DOI 10.3390/ijms24054554, PubMed 36901982
Desgranges S, Juzenas P, Vasovic V, Gederaas OA, Lindgren M, Warloe T, Peng Q, Contino-Pépin C(2022) Amphiphilic Protoporphyrin IX Derivatives as New Photosensitizing Agents for the Improvement of Photodynamic Therapy Biomedicines, 10(2) DOI 10.3390/biomedicines10020423, PubMed 35203632
Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q(2022) Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells Biomedicines, 10(2) DOI 10.3390/biomedicines10020232, PubMed 35203441