Semiconductor nanoparticles, so-called quantum dots, are being used for fluorescent imaging of cancer cells in vitro and in animals in vivo. We introduce the concept of using these nanoparticles as photosensitizers. Real-time monitoring using Electric Cell-substrate Impedance Sensing (ECIS) of cancer cell responses to photodynamic toxicity caused by quantum dots are studied in this project.
Liukaityte R, Stenberg VY, Kleinauskas A, Juzenas P, Urbanucci A, Juzeniene A(2025) Combination of PSMA targeting alpha-emitting radioligand [212Pb]Pb-AB001 with BET bromodomain inhibitors in in vitro prostate cancer models Med Oncol, 42(8), 362 DOI 10.1007/s12032-025-02925-9, PubMed 40694184
Espeland K, Christensen E, Aandahl A, Ulvær A, Warloe T, Kleinauskas A, Darvekar S, Juzenas P, Vasovic V, Peng Q, Jahnsen J(2024) Extracorporeal Photopheresis with 5-Aminolevulinic Acid in Crohn's Disease-A First-in-Human Phase I/II Study J Clin Med, 13(20) DOI 10.3390/jcm13206198, PubMed 39458148
Christensen E, Foss OA, Holien T, Juzenas P, Peng Q(2024) Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Cutaneous T-Cell Lymphoma: A First-in-Human Phase I/II Study Pharmaceutics, 16(6) DOI 10.3390/pharmaceutics16060815, PubMed 38931936