IBSEN III (IBSEN III - Inflammatory Bowel Disease in South Eastern Norway - Institute of Clinical Medicine (uio.no)) is an observational, prospective population-based inception cohort study, including patients at all 15 hospitals in the South Eastern Health Region (HSØ). In total 2254 IBD patients and controls were included between 2017 and 2019. Today, the five-year follow-up is ongoing, and the study has become one of the world largest treatment naïve, and population-based IBD cohorts. Importantly the study includes a very large biobank with biological materials sampled at time of diagnosis and prospectively at one and five years.

Thirteen ongoing PhD projects and one postdoc at seven hospitals in HSØ is a major asset for the IBD research environment not only at OUH but in the whole region. The PhD projects span from clinical epidemiology, PROM-research, dietary epidemiology, and health economy to cutting edge translational projects on microbiomics, proteomics and transcriptomics.

Project title

PhD student


Changes in epidemiology and treatment strategies in IBD disease; implications for the health service and the social security services

Charlotte Lund

OUH, Dept. of Gastroenterology  

A new Norwegian population-based study in pediatric IBD

Svend Andersen

Vestfold Hospital, Dept of Pediatrics

Clinical disease course in newly diagnosed IBD in the biological era

Vibeke Strande 

Lovisenberg Hospital, Dept. of Gastroenterology  

Proteomics as diagnostic and prognostic biomarkers in IBD

Charlotte Bache-Wiig Mathisen 

OUH, Dept. of Gastroenterology and Ørebro University Hospital

Biomarkers of fibrosis in Crohn’s disease – prognostic and predictive potential

Ida Glad 

Lovisenberg Hospital, Dept. of Gastroenterology and Nordic Bioscience

Precision-MAID: Microbial Precision Medicine assisted by Artificial Intelligence in IBD

Simen Hyll Hansen

OUH, Rikshospitalet, Norwegian PSC Center

Precision microbiome profiling in diagnosis and disease prediction in IBD

Maria Maaseng

OUH, Dept. of Gastroenterology, UiO and BioMe

Spatial transcriptomics to predict treatment response in Crohn’s disease

Karoline Rapp Vander-Elst

OUH, Dept. of Pathology

The missing heritability of IBD-a family study

Tone Bergene Aabrekke

Vestfold Hospital, Dept. of Gastroenterology  

Symptom burden in patients with IBD - impact on health-related quality of life and sick leave

Ingunn Johannesen

Østfold University College and Østfold Hospital, Dept. of Gastroenterologu

Health-related quality of life during the first year with IBD

Bjørn Olsen

Telemark Hospital, Dept. of Gastroenterology

Fatigue in IBD: Symptom course and prognostic factors the first year of diagnosis

Kristina Holten

Østfold Hospital, Dept. of Gastroenterology

What did IBSEN eat? Diet in IBD

Insaf Zerouga

OUH, Dept. of nutrition



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