Bente Halvorsen
- Group leader, Professor; PhD
- +47 23 07 27 83, 984 60 647
Publications 2024
Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
NPJ Vaccines, 9 (1), 185
DOI 10.1038/s41541-024-00972-3, PubMed 39384763
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241
Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus
Cardiovasc Diabetol, 23 (1), 146
DOI 10.1186/s12933-024-02237-8, PubMed 38685051
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005
Plasma legumain in familial hypercholesterolemia: associations with statin use and cardiovascular risk markers
Scand J Clin Lab Invest, 84 (1), 24-29
DOI 10.1080/00365513.2024.2309617, PubMed 38319290
Elevated interleukin 8 and matrix metalloproteinase 9 levels are associated with myocardial pathology in users of anabolic-androgenic steroids
Eur J Prev Cardiol, 31 (12), 1469-1476
DOI 10.1093/eurjpc/zwae126, PubMed 38573232
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108
Human papilloma virus vaccine induced thrombocytopenia accompanied by a wide spectrum of reversible inflammatory responses - a case report
Scand J Clin Lab Invest, 84 (6), 425-427
DOI 10.1080/00365513.2024.2400663, PubMed 39264796
Circular RNA Profile in Atherosclerotic Disease: Regulation during ST-Elevated Myocardial Infarction
Int J Mol Sci, 25 (16)
DOI 10.3390/ijms25169014, PubMed 39201700
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714
Neutrophil Extracellular Traps in ST-Segment Elevation Myocardial Infarction: Reduced by Tocilizumab and Associated With Infarct Size
JACC Adv, 3 (9), 101193
DOI 10.1016/j.jacadv.2024.101193, PubMed 39247678
CD38 deficient mice are not protected from atherosclerosis
Biochem Biophys Res Commun, 705, 149734
DOI 10.1016/j.bbrc.2024.149734, PubMed 38430607
Adherence to the Healthy Nordic Food Index is associated with reduced plasma levels of inflammatory markers in patients with heterozygous familial hypercholesterolemia
Atheroscler Plus, 58, 38-45
DOI 10.1016/j.athplu.2024.10.003, PubMed 39525275
Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Atherosclerosis, 392, 117507
DOI 10.1016/j.atherosclerosis.2024.117507, PubMed 38663317
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice
Front Immunol, 15, 1383505
DOI 10.3389/fimmu.2024.1383505, PubMed 38686379
Continuous infusion of resolvin D2 in combination with Angiotensin-II show contrary effects on blood pressure and intracardiac artery remodeling
Biochem Biophys Res Commun, 733, 150706
DOI 10.1016/j.bbrc.2024.150706, PubMed 39305571
Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
Genome Med, 16 (1), 27
DOI 10.1186/s13073-024-01296-6, PubMed 38331891
Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs
Physiol Rep, 12 (14), e16143
DOI 10.14814/phy2.16143, PubMed 39034131
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800
Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI
Int J Cardiol, 418, 132613
DOI 10.1016/j.ijcard.2024.132613, PubMed 39374793
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872
Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study
Front Immunol, 15, 1385377
DOI 10.3389/fimmu.2024.1385377, PubMed 38711510
Publications 2023
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989
Increased cardiovascular mortality during the COVID-19 pandemic: do not neglect causality
Eur Heart J Open, 3 (6), oead119
DOI 10.1093/ehjopen/oead119, PubMed 38089856
Disturbed lipid profile in common variable immunodeficiency - a pathogenic loop of inflammation and metabolic disturbances
Front Immunol, 14, 1199727
DOI 10.3389/fimmu.2023.1199727, PubMed 37545531
Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
J Clin Immunol, 43 (6), 1229-1240
DOI 10.1007/s10875-023-01475-x, PubMed 36995502
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572
Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
Front Cardiovasc Med, 10, 1160030
DOI 10.3389/fcvm.2023.1160030, PubMed 37332580
Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome
J Infect, 86 (6), 593-595
DOI 10.1016/j.jinf.2023.03.002, PubMed 36889510
Prediction of underlying atrial fibrillation in patients with a cryptogenic stroke: results from the NOR-FIB Study
J Neurol, 270 (8), 4049-4059
DOI 10.1007/s00415-023-11680-8, PubMed 37162578
Underlying causes of cryptogenic stroke and TIA in the nordic atrial fibrillation and stroke (NOR-FIB) study - the importance of comprehensive clinical evaluation
BMC Neurol, 23 (1), 115
DOI 10.1186/s12883-023-03155-0, PubMed 36944929
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis
Cardiovasc Res, 118 (17), 3346-3359
DOI 10.1093/cvr/cvac032, PubMed 35325057
Increased plasma levels of non-sugar sweeteners in patients with symptomatic carotid atherosclerosis
Scand Cardiovasc J, 57 (1), 2205068
DOI 10.1080/14017431.2023.2205068, PubMed 37102258
Biomarkers predictive of atrial fibrillation in patients with cryptogenic stroke. Insights from the Nordic Atrial Fibrillation and Stroke (NOR-FIB) study
Eur J Neurol, 30 (5), 1352-1363
DOI 10.1111/ene.15746, PubMed 36786305
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
Open Heart, 10 (2)
DOI 10.1136/openhrt-2023-002301, PubMed 37591633
Publications 2022
Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
Front Immunol, 13, 875152
DOI 10.3389/fimmu.2022.875152, PubMed 35911763
Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
Front Immunol, 13, 1051156
DOI 10.3389/fimmu.2022.1051156, PubMed 36263024
Use of High-Dose Androgens Is Associated with Reduced Brain-Derived Neurotrophic Factor in Male Weightlifters
Neuroendocrinology, 113 (1), 36-47
DOI 10.1159/000526418, PubMed 35944495
SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice
DNA Repair (Amst), 120, 103410
DOI 10.1016/j.dnarep.2022.103410, PubMed 36244177
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair
Adv Sci (Weinh), 10 (5), e2203053
DOI 10.1002/advs.202203053, PubMed 36526599
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188
Pro-inflammatory cytokines in cystic glioblastoma: A quantitative study with a comparison with bacterial brain abscesses. With an MRI investigation of displacement and destruction of the brain tissue surrounding a glioblastoma
Front Oncol, 12, 846674
DOI 10.3389/fonc.2022.846674, PubMed 35965529
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178
NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length
Biochem Biophys Rep, 29, 101211
DOI 10.1016/j.bbrep.2022.101211, PubMed 35079641
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
J Allergy Clin Immunol, 151 (3), 767-777
DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
Fetuin-A mediates the difference in adipose tissue insulin resistance between young adult pakistani and norwegian patients with type 2 diabetes
BMC Endocr Disord, 22 (1), 208
DOI 10.1186/s12902-022-01127-y, PubMed 35978354
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
Infect Dis (Lond), 54 (12), 918-923
DOI 10.1080/23744235.2022.2113135, PubMed 35984738
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
J Inflamm Res, 15, 6629-6644
DOI 10.2147/JIR.S379331, PubMed 36514358
Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies
Stroke, 53 (6), 2114-2122
DOI 10.1161/STROKEAHA.121.037581, PubMed 35240858
Atrial fibrillation in cryptogenic stroke and TIA patients in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Main results
Eur Stroke J, 8 (1), 148-156
DOI 10.1177/23969873221123122, PubMed 37021182
Atrial fibrillation in cryptogenic stroke and TIA patients in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Main results
European Stroke Journal, 0 (0), 1-9
DOI 10.1177/23969873221123122, PublikaID 431
Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss
Cardiovasc Diabetol, 21 (1), 36
DOI 10.1186/s12933-022-01469-w, PubMed 35277168
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep, 12 (1), 22378
DOI 10.1038/s41598-022-26759-x, PubMed 36572703
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063
Publications 2021
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738
Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross-sectional study
J Intern Med, 290 (5), 1083-1097
DOI 10.1111/joim.13383, PubMed 34506681
Identifying drivers for the direct rebound when energy efficiency is unknown. The importance of substitution and scale effects
Energy, 222, 119879
DOI 10.1016/j.energy.2021.119879
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870
The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure
Front Immunol, 12, 800978
DOI 10.3389/fimmu.2021.800978, PubMed 35003128
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0, PubMed 34611194
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J Am Heart Assoc, 10 (14), e020656
DOI 10.1161/JAHA.120.020656, PubMed 34259011
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
Sci Immunol, 6 (66), eabf2489
DOI 10.1126/sciimmunol.abf2489, PubMed 34932384
IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria
BMC Infect Dis, 21 (1), 1073
DOI 10.1186/s12879-021-06751-y, PubMed 34663245
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
J Clin Immunol, 42 (1), 146-157
DOI 10.1007/s10875-021-01146-9, PubMed 34669143
Publications 2020
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 9 (17), e016360
DOI 10.1161/JAHA.120.016360, PubMed 32809893
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Subjects with familial hypercholesterolemia have lower aortic valve area and higher levels of inflammatory biomarkers
J Clin Lipidol, 15 (1), 134-141
DOI 10.1016/j.jacl.2020.12.006, PubMed 33358307
Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
Scand Cardiovasc J, 54 (5), 274-279
DOI 10.1080/14017431.2020.1775878, PubMed 32500743
A population-based study of inflammatory mechanisms and pain sensitivity
Pain, 161 (2), 338-350
DOI 10.1097/j.pain.0000000000001731, PubMed 31651577
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20
DOI 10.1159/000504529, PubMed 32028277
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476
Publications 2019
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024, PubMed 31345784
Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
J Immunol, 203 (4), 853-863
DOI 10.4049/jimmunol.1900503, PubMed 31270150
Effect of hormone replacement therapy on atherogenic lipid profile in postmenopausal women
Thromb Res, 184, 1-7
DOI 10.1016/j.thromres.2019.10.005, PubMed 31677448
Levels of Lipoprotein (a) in patients with coronary artery disease with and without inflammatory rheumatic disease: a cross-sectional study
BMJ Open, 9 (5), e030651
DOI 10.1136/bmjopen-2019-030651, PubMed 31079089
Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure
Scand Cardiovasc J, 53 (4), 213-219
DOI 10.1080/14017431.2019.1629004, PubMed 31169417
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568
Plasma tumour necrosis factor correlates with mRNA expression of tumour necrosis factor and mitochondrial transcription factors in skeletal muscle in patients with chronic heart failure treated with cardiac resynchronization therapy: potential role in myopathy
Eur J Prev Cardiol, 27 (19), 2362-2366
DOI 10.1177/2047487319855796, PubMed 31389718
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol, 197 (1), 74-82
DOI 10.1111/cei.13283, PubMed 30821848
Atrial fibrillation in cryptogenic stroke and transient ischaemic attack - The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Rationale and design
Eur Stroke J, 4 (2), 172-180
DOI 10.1177/2396987319837089, PubMed 31259265
Increased Endothelial Activation in Patients with Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis, 29 (2), 104563
DOI 10.1016/j.jstrokecerebrovasdis.2019.104563, PubMed 31831329
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development
Thromb Haemost, 120 (2), 344-347
DOI 10.1055/s-0039-3400746, PubMed 31837653
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283
Publications 2018
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151
Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
J Acquir Immune Defic Syndr, 78 (4), 450-457
DOI 10.1097/QAI.0000000000001693, PubMed 29874201
Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
BMC Cancer, 18 (1), 739
DOI 10.1186/s12885-018-4659-0, PubMed 30005623
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Int J Cardiol, 271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572
Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders
CNS Neurol Disord Drug Targets, 17 (8), 626-639
DOI 10.2174/1871527317666180720163221, PubMed 30033880
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254
Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery
Acta Anaesthesiol Scand, 62 (6), 829-838
DOI 10.1111/aas.13104, PubMed 29512121
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Open Heart, 5 (2), e000765
DOI 10.1136/openhrt-2017-000765, PubMed 30258647
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Int J Cardiol, 274, 348-350
DOI 10.1016/j.ijcard.2018.06.093, PubMed 29961573
Publications 2017
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371
Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study
Atherosclerosis, 266, 48-57
DOI 10.1016/j.atherosclerosis.2017.09.021, PubMed 28963918
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem Biophys Res Commun, 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070, PubMed 28712870
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
PLoS One, 12 (11), e0188387
DOI 10.1371/journal.pone.0188387, PubMed 29176764
Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics
Lipids Health Dis, 16 (1), 115
DOI 10.1186/s12944-017-0511-9, PubMed 28606150
Increased expression of TFPI in human carotid stenosis
Thromb Res, 155, 31-37
DOI 10.1016/j.thromres.2017.04.024, PubMed 28482260
Publications 2016
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183
Revisiting household energy rebound: Perspectives from a multidisciplinary study
Indoor Built Environ., 25 (7), 1114-1123
DOI 10.1177/1420326X16629725
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
DOI 10.1007/s00125-016-4036-y, PubMed 27421726
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis
Atherosclerosis, 257, 216-223
DOI 10.1016/j.atherosclerosis.2016.11.026, PubMed 27940038
Lack of Effects of a Single High-Fat Meal Enriched with Vegetable n-3 or a Combination of Vegetable and Marine n-3 Fatty Acids on Intestinal Peptide Release and Adipokines in Healthy Female Subjects
Front Nutr, 3, 38
DOI 10.3389/fnut.2016.00038, PubMed 27630989
Complement activation by cholesterol crystals triggers a subsequent cytokine response
Mol Immunol, 84, 43-50
DOI 10.1016/j.molimm.2016.09.019, PubMed 27692470
High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
Cytokine, 83, 269-274
DOI 10.1016/j.cyto.2016.05.006, PubMed 27180202
Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
Clin Microbiol Infect, 22 (8), 734.e1-6
DOI 10.1016/j.cmi.2016.05.010, PubMed 27217049
Bioavailability of n-3 fatty acids from n-3-enriched foods and fish oil with different oxidative quality in healthy human subjects: a randomised single-meal cross-over study
J Nutr Sci, 5, e43
DOI 10.1017/jns.2016.34, PubMed 28620470
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
J Immunol, 196 (12), 5064-74
DOI 10.4049/jimmunol.1502595, PubMed 27183610
Sputum neutrophils are elevated in smelter workers, and systemic neutrophils are associated with rapid decline in FEV1
Occup Environ Med, 73 (7), 459-66
DOI 10.1136/oemed-2015-103083, PubMed 27052769
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939
EPAS1/HIF-2 alpha-mediated downregulation of tissue factor pathway inhibitor leads to a pro-thrombotic potential in endothelial cells
Biochim Biophys Acta, 1862 (4), 670-678
DOI 10.1016/j.bbadis.2016.01.017, PubMed 26826018
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Sci Transl Med, 8 (333), 333ra50
DOI 10.1126/scitranslmed.aad6100, PubMed 27053774
Publications 2015
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806
Brain derived neurotrophic factor (BDNF) and autism spectrum disorders (ASD) in childhood
Eur J Paediatr Neurol, 19 (4), 411-4
DOI 10.1016/j.ejpn.2015.03.005, PubMed 25847750
A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases
Expert Rev Cardiovasc Ther, 14 (3), 391-403
DOI 10.1586/14779072.2016.1128828, PubMed 26641944
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139
Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia
Atherosclerosis, 243 (1), 155-60
DOI 10.1016/j.atherosclerosis.2015.09.014, PubMed 26386212
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6 (7), e95
DOI 10.1038/ctg.2015.23, PubMed 26133108
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study
DNA Repair (Amst), 28, 21-7
DOI 10.1016/j.dnarep.2015.01.013, PubMed 25703835
Publications 2014
Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis
PLoS One, 9 (1), e84935
DOI 10.1371/journal.pone.0084935, PubMed 24400123
CXCR4 blockade induces atherosclerosis by affecting neutrophil function
J Mol Cell Cardiol, 74, 44-52
DOI 10.1016/j.yjmcc.2014.04.021, PubMed 24816217
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells
Cardiovasc Res, 102 (1), 148-56
DOI 10.1093/cvr/cvu036, PubMed 24518141
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α
Biochem Biophys Res Commun, 450 (4), 1525-30
DOI 10.1016/j.bbrc.2014.07.036, PubMed 25035925
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
Atherosclerosis, 234 (2), 352-9
DOI 10.1016/j.atherosclerosis.2014.03.021, PubMed 24732574
Subjects with familial hypercholesterolemia are characterized by an inflammatory phenotype despite long-term intensive cholesterol lowering treatment
Atherosclerosis, 233 (2), 561-567
DOI 10.1016/j.atherosclerosis.2014.01.022, PubMed 24530965
Markers of atherosclerotic development in children with familial hypercholesterolemia: a literature review
Atherosclerosis, 235 (2), 299-309
DOI 10.1016/j.atherosclerosis.2014.05.917, PubMed 24908240
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in ApoE-deficient mice
PLoS One, 9 (5), e97598
DOI 10.1371/journal.pone.0097598, PubMed 24840793
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
J Intern Med, 277 (6), 717-26
DOI 10.1111/joim.12328, PubMed 25382824
Publications 2013
Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
PLoS One, 8 (8), e72769
DOI 10.1371/journal.pone.0072769, PubMed 24023645
Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma
Brain Behav Immun, 30, 80-7
DOI 10.1016/j.bbi.2013.01.006, PubMed 23333795
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297
Households' heating investments: The effect of motives and attitudes on choice of equipment
Biomass Bioenerg., 57, 4-12
DOI 10.1016/j.biombioe.2013.01.027
The impact of lifestyle and attitudes on residential firewood demand in Norway
Biomass Bioenerg., 57, 13-21
DOI 10.1016/j.biombioe.2013.01.024
Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype
Genes Nutr, 8 (4), 425-34
DOI 10.1007/s12263-012-0329-z, PubMed 23296345
An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoe(-/-) mice
PLoS One, 8 (12), e81963
DOI 10.1371/journal.pone.0081963, PubMed 24324736
De novo 19p13.2 microdeletion encompassing the insulin receptor and resistin genes in a patient with obesity and learning disability
Am J Med Genet A, 161A (6), 1480-6
DOI 10.1002/ajmg.a.35927, PubMed 23637016
Publications 2012
High levels of S100A12 are associated with recent plaque symptomatology in patients with carotid atherosclerosis
Stroke, 43 (5), 1347-53
DOI 10.1161/STROKEAHA.111.642256, PubMed 22382154
A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells
PLoS One, 7 (9), e43638
DOI 10.1371/journal.pone.0043638, PubMed 23028464
Unraveling the role of nicotinamide phosphoribosyltransferase on lipids in atherosclerosis
Clin. Lipidol., 7 (6), 697-707
DOI 10.2217/CLP.12.71
Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology
Annu Rev Nutr, 32, 229-43
DOI 10.1146/annurev-nutr-071811-150746, PubMed 22462624
Visfatin/NAMPT - a hot spot in thrombosis?
Thromb Res, 130 (3), 289-90
DOI 10.1016/j.thromres.2012.06.027, PubMed 22809845
Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies
PLoS One, 7 (7), e40673
DOI 10.1371/journal.pone.0040673, PubMed 22815786
Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients
Free Radic Biol Med, 52 (8), 1318-24
DOI 10.1016/j.freeradbiomed.2012.02.012, PubMed 22343420
Oxidized LDL level is related to gene expression of tumour necrosis factor super family members in children and young adults with familial hypercholesterolaemia
J Intern Med, 273 (1), 69-78
DOI 10.1111/j.1365-2796.2012.02584.x, PubMed 22891927
Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH
Thromb Res, 131 (2), 178-82
DOI 10.1016/j.thromres.2012.11.008, PubMed 23199546
LDL-apheresis affects markers of endothelial function in patients with homozygous familial hypercholesterolemia
Thromb Res, 130 (5), 823-5
DOI 10.1016/j.thromres.2012.06.004, PubMed 22728023
Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis
J Clin Lipidol, 7 (2), 109-16
DOI 10.1016/j.jacl.2012.08.001, PubMed 23415429
Elevated serum MMP-9/TIMP-1 ratio in patients with homozygous familial hypercholesterolemia: effects of LDL-apheresis
Cytokine, 61 (1), 194-8
DOI 10.1016/j.cyto.2012.09.016, PubMed 23131422
Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
J Clin Endocrinol Metab, 97 (4), 1355-62
DOI 10.1210/jc.2011-2417, PubMed 22319029
Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Atherosclerosis, 224 (1), 266-73
DOI 10.1016/j.atherosclerosis.2012.06.071, PubMed 22840692
Substitution of TAG oil with diacylglycerol oil in food items improves the predicted 10 years cardiovascular risk score in healthy, overweight subjects
J Nutr Sci, 1, e17
DOI 10.1017/jns.2012.18, PubMed 25191546
Publications 2011
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
DOI 10.2337/db10-1493, PubMed 21464440
Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
J Infect, 63 (4), 308-16
DOI 10.1016/j.jinf.2011.07.004, PubMed 21781987
Nicotinamide phosphoribosyltransferase and lipid accumulation in macrophages
Eur J Clin Invest, 41 (10), 1098-104
DOI 10.1111/j.1365-2362.2011.02515.x, PubMed 21426336
Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity
Circ Res, 109 (12), 1387-95
DOI 10.1161/CIRCRESAHA.111.256529, PubMed 22021930
Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
DOI 10.1530/EJE-11-0864, PubMed 22170794
Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke
PLoS One, 6 (12), e28785
DOI 10.1371/journal.pone.0028785, PubMed 22174896
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626
Effect of the fat composition of a single high-fat meal on inflammatory markers in healthy young women
Br J Nutr, 106 (12), 1826-35
DOI 10.1017/S0007114511002510, PubMed 21736782
Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors
Inflamm Res, 60 (4), 309-19
DOI 10.1007/s00011-010-0302-5, PubMed 21229287
Activated leukocyte cell adhesion molecule and prognosis in acute ischemic stroke
Stroke, 42 (9), 2453-8
DOI 10.1161/STROKEAHA.110.612440, PubMed 21757661
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
Br J Dermatol, 164 (2), 344-55
DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993
Soluble CXCL16 and long-term outcome in acute ischemic stroke
Atherosclerosis, 220 (1), 244-9
DOI 10.1016/j.atherosclerosis.2011.10.004, PubMed 22055341
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157
Activin A in nonalcoholic fatty liver disease
Vitam Horm, 85, 323-42
DOI 10.1016/B978-0-12-385961-7.00015-9, PubMed 21353887
Publications 2010
Activated platelets and atherosclerosis
Expert Rev Cardiovasc Ther, 8 (9), 1297-307
DOI 10.1586/erc.10.92, PubMed 20828352
Tumor necrosis factor superfamily molecules in acute coronary syndromes
Ann Med, 43 (2), 90-103
DOI 10.3109/07853890.2010.523711, PubMed 21039303
Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation
Cardiovasc Res, 86 (2), 265-73
DOI 10.1093/cvr/cvq044, PubMed 20139115
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873
The peripheral blood mononuclear cell microRNA signature of coronary artery disease
Biochem Biophys Res Commun, 394 (3), 792-7
DOI 10.1016/j.bbrc.2010.03.075, PubMed 20230787
Increased YKL-40 expression in patients with carotid atherosclerosis
Atherosclerosis, 211 (2), 589-95
DOI 10.1016/j.atherosclerosis.2010.02.035, PubMed 20347092
Children with familial hypercholesterolemia are characterized by an inflammatory imbalance between the tumor necrosis factor α system and interleukin-10
Atherosclerosis, 214 (1), 163-8
DOI 10.1016/j.atherosclerosis.2010.10.002, PubMed 21040915
Toll like receptor 5 (TLR5) may be involved in the immunological response to Aspergillus fumigatus in vitro
Med Mycol, 49 (4), 375-9
DOI 10.3109/13693786.2010.531772, PubMed 21067314
Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)
BMC Med Genet, 11, 144
DOI 10.1186/1471-2350-11-144, PubMed 20939869
Publications 2009
Tangier disease caused by compound heterozygosity for ABCA1 mutations R282X and Y1532C
Atherosclerosis, 209 (1), 163-6
DOI 10.1016/j.atherosclerosis.2009.08.039, PubMed 19765707
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication
Clin Exp Immunol, 157 (3), 400-7
DOI 10.1111/j.1365-2249.2009.03976.x, PubMed 19664149
Chemokines and common variable immunodeficiency; possible contribution of CCL19, CCL21 and CCR7 to immune dysregulation
Clin Exp Immunol, 158 (2), 237-45
DOI 10.1111/j.1365-2249.2009.04013.x, PubMed 19747210
Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptor antagonist in individuals with metabolic syndrome
Eur J Endocrinol, 162 (2), 267-73
DOI 10.1530/EJE-09-0706, PubMed 19926782
Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome
Scand J Clin Lab Invest, 69 (8), 858-64
DOI 10.3109/00365510903348677, PubMed 19929281
CXCL16 in HIV infection - a link between inflammation and viral replication
Eur J Clin Invest, 39 (11), 1017-24
DOI 10.1111/j.1365-2362.2009.02207.x, PubMed 19674076
Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis
Infect Immun, 78 (3), 1269-75
DOI 10.1128/IAI.01091-09, PubMed 20008537
The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis
Thromb Haemost, 102 (4), 704-10
DOI 10.1160/TH08-10-0665, PubMed 19806256
Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
Inhal Toxicol, 21 (8), 674-81
DOI 10.1080/08958370802491425, PubMed 19558225
Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
J Clin Endocrinol Metab, 95 (1), 361-8
DOI 10.1210/jc.2009-0422, PubMed 19880791
Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly
Endocr Rev, 30 (7), 927
DOI 10.1210/edrv.30.7.9997, PubMed 28199500
Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Arterioscler Thromb Vasc Biol, 29 (8), 1228-34
DOI 10.1161/ATVBAHA.109.189761, PubMed 19498175
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
DOI 10.1152/japplphysiol.90719.2008, PubMed 19196915
Publications 2008
Chemokines and cardiovascular risk
Arterioscler Thromb Vasc Biol, 28 (11), 1909-19
DOI 10.1161/ATVBAHA.107.161240, PubMed 18669888
The complex role of T-cell-based immunity in atherosclerosis
Curr Atheroscler Rep, 10 (3), 236-43
DOI 10.1007/s11883-008-0037-8, PubMed 18489852
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
DOI 10.1161/ATVBAHA.108.162305, PubMed 18276907
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
DOI 10.1016/j.ejheart.2008.02.010, PubMed 18353719
Atherosclerotic plaque stability--what determines the fate of a plaque?
Prog Cardiovasc Dis, 51 (3), 183-94
DOI 10.1016/j.pcad.2008.09.001, PubMed 19026853
Smoking and Inflammation: Their Synergistic Roles in Chronic Disease
Curr. Cardiovascu. Risk Rep., 2 (6), 446-451
DOI 10.1007/s12170-008-0079-z
Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability
Stroke, 39 (11), 3092-5
DOI 10.1161/STROKEAHA.108.517128, PubMed 18723424
The antiatherogenic function of HDL is impaired in hyperhomocysteinemic subjects
J Nutr, 138 (11), 2070-5
DOI 10.3945/jn.108.090704, PubMed 18936200
Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis
Circ Res, 104 (1), 60-8
DOI 10.1161/CIRCRESAHA.108.188078, PubMed 19023130
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins
Cardiovasc Res, 79 (1), 195-203
DOI 10.1093/cvr/cvn071, PubMed 18339644
Publications 2007
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization
Circulation, 115 (8), 972-80
DOI 10.1161/CIRCULATIONAHA.106.665893, PubMed 17283255
Effect of smoking cessation on markers of inflammation and endothelial cell activation among individuals with high risk for cardiovascular disease
Scand J Clin Lab Invest, 67 (6), 604-11
DOI 10.1080/00365510701283878, PubMed 17852807
Airway inflammation in paper mill workers
J Occup Environ Med, 49 (10), 1135-42
DOI 10.1097/JOM.0b013e31814b2e87, PubMed 18000418
Plasma levels of granzyme B are increased in patients with lipid-rich carotid plaques as determined by echogenicity
Atherosclerosis, 195 (2), e142-6
DOI 10.1016/j.atherosclerosis.2007.05.001, PubMed 17568588
Publications 2006
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Arterioscler Thromb Vasc Biol, 27 (3), 614-20
DOI 10.1161/01.ATV.0000255581.38523.7c, PubMed 17170367
Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties
Arterioscler Thromb Vasc Biol, 27 (3), 628-34
DOI 10.1161/01.ATV.0000255950.70774.d5, PubMed 17185614
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J Mol Cell Cardiol, 41 (4), 689-97
DOI 10.1016/j.yjmcc.2006.07.009, PubMed 16926021
Role of interleukin-10 in atherogenesis and plaque stabilization
Future Cardiol, 2 (1), 75-83
DOI 10.2217/14796678.2.1.75, PubMed 19804134
A protective anti-inflammatory phenotype in high-risk individuals who do not develop coronary artery disease
J Am Coll Cardiol, 47 (5), 1085-6
DOI 10.1016/j.jacc.2005.11.042, PubMed 16516099
Impaired inhibitory effect of interleukin-10 on the balance between matrix metalloproteinase-9 and its inhibitor in mononuclear cells from hyperhomocysteinemic subjects
Stroke, 37 (7), 1731-6
DOI 10.1161/01.STR.0000226465.84561.cb, PubMed 16728689
Triglyceride-rich HDL3 from patients with familial hypercholesterolemia are less able to inhibit cytokine release or to promote cholesterol efflux
J Nutr, 136 (4), 877-81
DOI 10.1093/jn/136.4.877, PubMed 16549444
[Lox-1--an actor in cardiovascular disease?]
Tidsskr Nor Laegeforen, 126 (6), 753-5
PubMed 16541167
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Arterioscler Thromb Vasc Biol, 26 (4), 857-63
DOI 10.1161/01.ATV.0000204334.48195.6a, PubMed 16424351
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
J Am Coll Cardiol, 48 (8), 1591-9
DOI 10.1016/j.jacc.2006.06.060, PubMed 17045893
Publications 2005
Potential role for immunomodulatory therapy in atherosclerotic plaque stabilisation
Expert Opin Pharmacother, 6 (13), 2169-80
DOI 10.1517/14656566.6.13.2169, PubMed 16218879
Inflammation in coronary artery disease: potential role for immunomodulatory therapy
Expert Rev Cardiovasc Ther, 3 (6), 1111-24
DOI 10.1586/14779072.3.6.1111, PubMed 16293001
Altered composition of HDL3 in FH subjects causing a HDL subfraction with less atheroprotective function
Clin Chim Acta, 359 (1-2), 171-8
DOI 10.1016/j.cccn.2005.03.050, PubMed 15936009
Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways
Arterioscler Thromb Vasc Biol, 25 (7), 1364-9
DOI 10.1161/01.ATV.0000171982.57713.96, PubMed 15920037
Down-regulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha
Biochim Biophys Acta, 1734 (3), 235-46
DOI 10.1016/j.bbalip.2005.02.011, PubMed 15893958
Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling
Cardiovasc Res, 67 (1), 106-15
DOI 10.1016/j.cardiores.2005.02.016, PubMed 15949474
Chemokines in children with heterozygous familiar hypercholesterolemia: selective upregulation of RANTES
Arterioscler Thromb Vasc Biol, 26 (1), 200-5
DOI 10.1161/01.ATV.0000193619.67288.ed, PubMed 16254204
Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8
Pediatr Res, 58 (3), 542-8
DOI 10.1203/01.PDR.0000179407.46810.2D, PubMed 16148071
Coffee consumption and human health--beneficial or detrimental?--Mechanisms for effects of coffee consumption on different risk factors for cardiovascular disease and type 2 diabetes mellitus
Mol Nutr Food Res, 49 (3), 274-84
DOI 10.1002/mnfr.200400109, PubMed 15704241
Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis
Circulation, 112 (14), 2121-9
DOI 10.1161/CIRCULATIONAHA.105.544676, PubMed 16186421
Increased expression of chemokines in patients with Wegener's granulomatosis - modulating effects of methylprednisolone in vitro
Clin Exp Immunol, 140 (2), 376-83
DOI 10.1111/j.1365-2249.2005.02770.x, PubMed 15807865
Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-8
DOI 10.1161/01.CIR.0000165119.62099.14, PubMed 15883214
Publications 2004
Expression of matrix metalloproteinases in patients with Wegener's granulomatosis
Ann Rheum Dis, 63 (12), 1659-63
DOI 10.1136/ard.2003.017954, PubMed 15547092
Increased myocardial matrix metalloproteinases in hypoxic newborn pigs during resuscitation: effects of oxygen and carbon dioxide
Eur J Clin Invest, 34 (7), 459-66
DOI 10.1111/j.1365-2362.2004.01378.x, PubMed 15255782
Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy
Eur J Clin Invest, 34 (10), 709-15
DOI 10.1111/j.1365-2362.2004.01410.x, PubMed 15473896
Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms
J Lipid Res, 46 (2), 211-9
DOI 10.1194/jlr.M400324-JLR200, PubMed 15547296
Abnormal interleukin-7 function in common variable immunodeficiency
Blood, 105 (7), 2887-90
DOI 10.1182/blood-2004-06-2423, PubMed 15598813
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets
Pediatr Res, 56 (5), 783-90
DOI 10.1203/01.PDR.0000141988.89820.E3, PubMed 15347772
8-isoprostane increases scavenger receptor A and matrix metalloproteinase activity in THP-1 macrophages, resulting in long-lived foam cells
Eur J Clin Invest, 34 (7), 451-8
DOI 10.1111/j.1365-2362.2004.01376.x, PubMed 15255781
Potential anti-inflammatory role of activin A in acute coronary syndromes
J Am Coll Cardiol, 44 (2), 369-75
DOI 10.1016/j.jacc.2004.03.069, PubMed 15261933
Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells - potential role of prostaglandin E2
Thromb Haemost, 92 (6), 1358-67
DOI 10.1160/TH04-03-0146, PubMed 15583745
Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
DOI 10.1161/01.CIR.0000120704.97934.41, PubMed 14993131
Publications 2003
Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects
Eur J Clin Invest, 33 (7), 555-60
DOI 10.1046/j.1365-2362.2003.01189.x, PubMed 12814391
Hyperhomocysteinemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells
J Nutr, 133 (11), 3588-91
DOI 10.1093/jn/133.11.3588, PubMed 14608078
8-isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases
Cardiovasc Res, 59 (4), 945-54
DOI 10.1016/s0008-6363(03)00538-8, PubMed 14553834
[Isoprostanes--new markers of oxidative stress]
Tidsskr Nor Laegeforen, 123 (3), 315-8
PubMed 12640897
Augmented PLA2 activity in pre-eclamptic decidual tissue--a key player in the pathophysiology of 'acute atherosis' in pre-eclampsia?
Placenta, 24 (10), 965-73
DOI 10.1016/s0143-4004(03)00175-9, PubMed 14580379
Publications 2002
Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects
Circulation, 106 (1), 36-42
DOI 10.1161/01.cir.0000020001.09990.90, PubMed 12093767
Inflammatory imbalance between IL-10 and TNFalpha in unstable angina potential plaque stabilizing effects of IL-10
Eur J Clin Invest, 32 (11), 803-10
DOI 10.1046/j.1365-2362.2002.01069.x, PubMed 12423320
Publications 2001
Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats
Ann Nutr Metab, 45 (1), 30-7
DOI 10.1159/000046703, PubMed 11244185
8-iso-prostaglandin F(2alpha) increases expression of LOX-1 in JAR cells
Hypertension, 37 (4), 1184-90
DOI 10.1161/01.hyp.37.4.1184, PubMed 11304522
Reduction of leptin gene expression by dietary polyunsaturated fatty acids
J Lipid Res, 42 (5), 743-50
PubMed 11352981
Publications 2000
Lithocholic acid and sulphated lithocholic acid differ in the ability to promote matrix metalloproteinase secretion in the human colon cancer cell line CaCo-2
Biochem J, 349 (Pt 1), 189-93
DOI 10.1042/0264-6021:3490189, PubMed 10861227
8-Iso-prostaglandin f(2alpha) reduces trophoblast invasion and matrix metalloproteinase activity
Hypertension, 35 (6), 1307-13
DOI 10.1161/01.hyp.35.6.1307, PubMed 10856282
Publications 1999
Uptake of vitamin A in macrophages from physiologic transport proteins: role of retinol-binding protein and chylomicron remnants
J Nutr Biochem, 10 (6), 345-52
DOI 10.1016/s0955-2863(99)00013-3, PubMed 15539309
Sulphation of lithocholic acid in the colon-carcinoma cell line CaCo-2
Biochem J, 343 Pt 3 (Pt 3), 533-9
DOI 10.1042/0264-6021:3430533, PubMed 10527930
Elevated level of free 8-iso-prostaglandin F2alpha in the decidua basalis of women with preeclampsia
Am J Obstet Gynecol, 181 (5 Pt 1), 1211-5
DOI 10.1016/s0002-9378(99)70110-9, PubMed 10561647
Publications 1998
Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts
J Lipid Res, 39 (4), 901-12
PubMed 9555953
Proteoglycans in macrophages: characterization and possible role in the cellular uptake of lipoproteins
Biochem J, 331 ( Pt 3) (Pt 3), 743-52
DOI 10.1042/bj3310743, PubMed 9560300
Publications 1997
Peroxidation of LDL from combined-hyperlipidemic male smokers supplied with omega-3 fatty acids and antioxidants
Arterioscler Thromb Vasc Biol, 17 (11), 2576-88
DOI 10.1161/01.atv.17.11.2576, PubMed 9409230
Effect of coffee lipids (cafestol and kahweol) on regulation of cholesterol metabolism in HepG2 cells
Arterioscler Thromb Vasc Biol, 17 (10), 2140-9
DOI 10.1161/01.atv.17.10.2140, PubMed 9351383
Cafestol (a coffee lipid) decreases uptake of low-density lipoprotein (LDL) in human skin fibroblasts and liver cells
Ann N Y Acad Sci, 827, 158-62
DOI 10.1111/j.1749-6632.1997.tb51830.x, PubMed 9329750
Publications 1996
Metabolism of low density lipoprotein: relation to certain nutrients, drugs, and proteoglycans
Institute for Nutrition Research, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 961573198, ISBN 82-992681-4-1
Effects of partially hydrogenated fish oil, partially hydrogenated soybean oil and butter on the susceptibility of low density lipoprotein to oxidative modification in men
Eur J Clin Nutr, 50 (6), 364-70
PubMed 8793417
Effect of homocysteine on copper ion-catalyzed, azo compound-initiated, and mononuclear cell-mediated oxidative modification of low density lipoprotein
J Lipid Res, 37 (7), 1591-600
PubMed 8827529
Inhibition of lipid peroxidation in low-density lipoprotein by the flavonoid myrigalone B and ascorbic acid
Biochem Pharmacol, 51 (12), 1719-25
DOI 10.1016/0006-2952(96)00107-4, PubMed 8687487
Publications 1995
Effect of long-chain mono-unsaturated and n-3 polyunsaturated fatty acids on postprandial blood and liver lipids in rats
Scand J Clin Lab Invest, 55 (6), 469-75
DOI 10.1080/00365519509075384, PubMed 8571076
Paracetamol inhibits copper ion-induced, azo compound-initiated, and mononuclear cell-mediated oxidative modification of LDL
Arterioscler Thromb Vasc Biol, 15 (9), 1338-44
DOI 10.1161/01.atv.15.9.1338, PubMed 7670947
Effect of a coffee lipid (cafestol) on regulation of lipid metabolism in CaCo-2 cells
J Lipid Res, 36 (10), 2079-89
PubMed 8576635
Publications 1993
The time courses of intracellular transport of some secretory proteins of rat liver are not affected by an induced acute phase response
Eur J Cell Biol, 60 (1), 108-14
PubMed 8462589
Publications 1992
Intracellulær transport av sekretoriske proteiner under indusert akutt inflammasjon i rotte
[B. Halvorsen], Oslo, 134 bl.
BIBSYS 921048408