Beata Grallert

  • Scientist, project leader
  • +47 22 78 19 80

Publications 2023

Stonyte V, Mastrangelopoulou M, Timmer R, Lindbergsengen L, Vietri M, Campsteijn C, Grallert B (2023)
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955

Publications 2022

Nilsen A, Hillestad T, Skingen VE, Aarnes EK, Fjeldbo CS, Hompland T, Evensen TS, Stokke T, Kristensen GB, Grallert B, Lyng H (2022)
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630

Publications 2021

Anda S, Boye E, Schink KO, Grallert B (2021)
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465

Publications 2019

Anda S, Grallert B (2019)
Cell-Cycle-Dependent Regulation of Translation: New Interpretations of Old Observations in Light of New Approaches
Bioessays, 41 (8), e1900022
DOI 10.1002/bies.201900022, PubMed 31210378

Boye E, Grallert B (2019)
eIF2α phosphorylation and the regulation of translation
Curr Genet, 66 (2), 293-297
DOI 10.1007/s00294-019-01026-1, PubMed 31485739

Landsverk HB, Sandquist LE, Sridhara SC, Rødland GE, Sabino JC, de Almeida SF, Grallert B, Trinkle-Mulcahy L, Syljuåsen RG (2019)
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res, 47 (4), 1797-1813
DOI 10.1093/nar/gky1233, PubMed 30541148

Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Nanotoxicology, 13 (6), 761-782
DOI 10.1080/17435390.2019.1576238, PubMed 30760074

Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194

Publications 2018

Bøe CA, Håland TW, Boye E, Syljuåsen RG, Grallert B (2018)
A novel role for ATR/Rad3 in G1 phase
Sci Rep, 8 (1), 6880
DOI 10.1038/s41598-018-25238-6, PubMed 29720710

Stonyte V, Boye E, Grallert B (2018)
Regulation of global translation during the cell cycle
J Cell Sci, 131 (17)
DOI 10.1242/jcs.220327, PubMed 30072440

Zach R, Tvaružková J, Schätz M, Tupa O, Grallert B, Prevorovský M (2018)
Mitotic defects in fission yeast lipid metabolism 'cut' mutants are suppressed by ammonium chloride
FEMS Yeast Res, 18 (6)
DOI 10.1093/femsyr/foy064, PubMed 29931271

Publications 2017

Anda S, Zach R, Grallert B (2017)
Activation of Gcn2 in response to different stresses
PLoS One, 12 (8), e0182143
DOI 10.1371/journal.pone.0182143, PubMed 28771613

Rothe C, Rødland GE, Anda S, Stonyte V, Boye E, Lopez-Aviles S, Grallert B (2017)
A checkpoint-independent mechanism delays entry into mitosis after UV irradiation
J Cell Sci, 130 (23), 4028-4037
DOI 10.1242/jcs.204693, PubMed 29046339

Publications 2016

Anda S, Rothe C, Boye E, Grallert B (2016)
Consequences of abnormal CDK activity in S phase
Cell Cycle, 15 (7), 963-73
DOI 10.1080/15384101.2016.1152423, PubMed 26918805

Boye E, Anda S, Rothe C, Stokke T, Grallert B (2016)
Analyzing Schizosaccharomyces pombe DNA Content by Flow Cytometry
Cold Spring Harb Protoc, 2016 (6)
DOI 10.1101/pdb.prot091280, PubMed 27250946

Publications 2015

Håland TW, Boye E, Stokke T, Grallert B, Syljuåsen RG (2015)
Simultaneous measurement of passage through the restriction point and MCM loading in single cells
Nucleic Acids Res, 43 (22), e150
DOI 10.1093/nar/gkv744, PubMed 26250117

Knutsen JH, Rødland GE, Bøe CA, Håland TW, Sunnerhagen P, Grallert B, Boye E (2015)
Stress-induced inhibition of translation independently of eIF2α phosphorylation
J Cell Sci, 128 (23), 4420-7
DOI 10.1242/jcs.176545, PubMed 26493332

Publications 2014

Anda S, Boye E, Grallert B (2014)
Cell-cycle analyses using thymidine analogues in fission yeast
PLoS One, 9 (2), e88629
DOI 10.1371/journal.pone.0088629, PubMed 24551125

Publications 2013

Grallert B, Boye E (2013)
GCN2, an old dog with new tricks
Biochem Soc Trans, 41 (6), 1687-91
DOI 10.1042/BST20130210, PubMed 24256275

Rødland GE, Tvegård T, Boye E, Grallert B (2013)
Crosstalk between the Tor and Gcn2 pathways in response to different stresses
Cell Cycle, 13 (3), 453-61
DOI 10.4161/cc.27270, PubMed 24280780

Publications 2012

Bøe CA, Knutsen JH, Boye E, Grallert B (2012)
Hpz1 modulates the G1-S transition in fission yeast
PLoS One, 7 (9), e44539
DOI 10.1371/journal.pone.0044539, PubMed 22970243

Bøe CA, Krohn M, Rødland GE, Capiaghi C, Maillard O, Thoma F, Boye E, Grallert B (2012)
Induction of a G1-S checkpoint in fission yeast
Proc Natl Acad Sci U S A, 109 (25), 9911-6
DOI 10.1073/pnas.1204901109, PubMed 22665798

Publications 2011

Knutsen JH, Rein ID, Rothe C, Stokke T, Grallert B, Boye E (2011)
Cell-cycle analysis of fission yeast cells by flow cytometry
PLoS One, 6 (2), e17175
DOI 10.1371/journal.pone.0017175, PubMed 21386895

Publications 2009

Boye E, Grallert B (2009)
In DNA replication, the early bird catches the worm
Cell, 136 (5), 812-4
DOI 10.1016/j.cell.2009.02.023, PubMed 19269359

Boye E, Skjølberg HC, Grallert B (2009)
Checkpoint regulation of DNA replication
Methods Mol Biol, 521, 55-70
DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101

Skjølberg HC, Fensgård O, Nilsen H, Grallert B, Boye E (2009)
Global transcriptional response after exposure of fission yeast cells to ultraviolet light
BMC Cell Biol, 10, 87
DOI 10.1186/1471-2121-10-87, PubMed 20015352

Publications 2008

Bøe CA, Garcia I, Pai CC, Sharom JR, Skjølberg HC, Boye E, Kearsey S, Macneill SA, Tyers MD, Grallert B (2008)
Rapid regulation of protein activity in fission yeast
BMC Cell Biol, 9, 23
DOI 10.1186/1471-2121-9-23, PubMed 18457584

Grallert B, Boye E (2008)
The multiple facets of the intra-S checkpoint
Cell Cycle, 7 (15), 2315-20
DOI 10.4161/cc.6389, PubMed 18677104

Krohn M, Skjølberg HC, Soltani H, Grallert B, Boye E (2008)
The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
J Cell Sci, 121 (Pt 24), 4047-54
DOI 10.1242/jcs.035428, PubMed 19033384

Publications 2007

Grallert B, Boye E (2007)
The Gcn2 kinase as a cell cycle regulator
Cell Cycle, 6 (22), 2768-72
DOI 10.4161/cc.6.22.4933, PubMed 17986863

Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, Grallert B, Boye E (2007)
A novel checkpoint mechanism regulating the G1/S transition
Genes Dev, 21 (6), 649-54
DOI 10.1101/gad.421807, PubMed 17369398

Publications 2004

Nilssen EA, Synnes M, Tvegård T, Vebø H, Boye E, Grallert B (2004)
Germinating fission yeast spores delay in G1 in response to UV irradiation
BMC Cell Biol, 5 (1), 40
DOI 10.1186/1471-2121-5-40, PubMed 15498101

Publications 2003

Nilssen EA, Synnes M, Kleckner N, Grallert B, Boye E (2003)
Intra-G1 arrest in response to UV irradiation in fission yeast
Proc Natl Acad Sci U S A, 100 (19), 10758-63
DOI 10.1073/pnas.1833769100, PubMed 12960401

Publications 2002

Synnes M, Nilssen EA, Boye E, Grallert B (2002)
A novel chk1-dependent G1/M checkpoint in fission yeast
J Cell Sci, 115 (Pt 18), 3609-18
DOI 10.1242/jcs.00004, PubMed 12186947

Publications 2001

Boye E, Grallert B (2001)
[The 2001 Nobel Prize in Physiology or Medicine]
Tidsskr Nor Laegeforen, 121 (30), 3500
PubMed 11808003

Publications 2000

Grallert B, Kearsey SE, Lenhard M, Carlson CR, Nurse P, Boye E, Labib K (2000)
A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
J Cell Sci, 113 ( Pt 8), 1447-58
DOI 10.1242/jcs.113.8.1447, PubMed 10725227

Publications 1999

Carlson CR, Grallert B, Stokke T, Boye E (1999)
Regulation of the start of DNA replication in Schizosaccharomyces pombe
J Cell Sci, 112 ( Pt 6), 939-46
DOI 10.1242/jcs.112.6.939, PubMed 10036243

Grallert A, Grallert B, Zilahi E, Szilagyi Z, Sipiczki M (1999)
Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation
Yeast, 15 (8), 669-86
DOI 10.1002/(SICI)1097-0061(19990615)15:8<669::AID-YEA411>3.0.CO;2-K, PubMed 10392445

Publications 1998

Grallert A, Grallert B, Ribar B, Sipiczki M (1998)
Coordination of initiation of nuclear division and initiation of cell division in Schizosaccharomyces pombe: genetic interactions of mutations
J Bacteriol, 180 (4), 892-900
DOI 10.1128/JB.180.4.892-900.1998, PubMed 9473044

Publications 1997

Carlson CR, Grallert B, Bernander R, Stokke T, Boye E (1997)
Measurement of nuclear DNA content in fission yeast by flow cytometry
Yeast, 13 (14), 1329-35
DOI 10.1002/(SICI)1097-0061(199711)13:14<1329::AID-YEA185>3.0.CO;2-M, PubMed 9392077

Grallert B, Nurse P (1997)
An approach to identify functional homologues and suppressors of genes in fission yeast
Curr Genet, 32 (1), 27-31
DOI 10.1007/s002940050244, PubMed 9309167

Publications 1996

Grallert B, Nurse P (1996)
The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase
Genes Dev, 10 (20), 2644-54
DOI 10.1101/gad.10.20.2644, PubMed 8895665

Publications 1995

D'Urso G, Grallert B, Nurse P (1995)
DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast
J Cell Sci, 108 ( Pt 9), 3109-18
DOI 10.1242/jcs.108.9.3109, PubMed 8537450

Publications 1993

Grallert B, Nurse P, Patterson TE (1993)
A study of integrative transformation in Schizosaccharomyces pombe
Mol Gen Genet, 238 (1-2), 26-32
DOI 10.1007/BF00279526, PubMed 8479431

Sipiczki M, Grallert B, Miklos I (1993)
Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations
J Cell Sci, 104 ( Pt 2), 485-93
DOI 10.1242/jcs.104.2.485, PubMed 8505375

Publications 1991

Grallert B, Sipiczki M (1991)
Common genes and pathways in the regulation of the mitotic and meiotic cell cycles of Schizosaccharomyces pombe
Curr Genet, 20 (3), 199-204
DOI 10.1007/BF00326233, PubMed 1934126

Publications 1990

Grallert B, Sipiczki M (1990)
Dissociation of meiotic and mitotic roles of the fission yeast cdc2 gene
Mol Gen Genet, 222 (2-3), 473-5
DOI 10.1007/BF00633860, PubMed 2274045

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