Awais Ahmad Mughal

  • MD, PhD

Identification of potential novel molecular targets in GBM and functional implications of gene knock-down.

 

Publications 2023

Brynjulvsen M, Solli E, Walewska M, Zucknick M, Djirackor L, Langmoen IA, Mughal AA, Skaga E, Vik-Mo EO, Sandberg CJ (2023)
Functional and Molecular Heterogeneity in Glioma Stem Cells Derived from Multiregional Sampling
Cancers (Basel), 15 (24)
DOI 10.3390/cancers15245826, PubMed 38136371

Publications 2018

Mughal AA, Zhang L, Fayzullin A, Server A, Li Y, Wu Y, Glass R, Meling T, Langmoen IA, Leergaard TB, Vik-Mo EO (2018)
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116

Publications 2016

Fayzullin A, Tuvnes FA, Skjellegrind HK, Behnan J, Mughal AA, Langmoen IA, Vik-Mo EO (2016)
Time-lapse phenotyping of invasive glioma cells ex vivo reveals subtype-specific movement patterns guided by tumor core signaling
Exp Cell Res, 349 (2), 199-213
DOI 10.1016/j.yexcr.2016.08.001, PubMed 27515001

Publications 2015

Joel M, Mughal AA, Grieg Z, Murrell W, Palmero S, Mikkelsen B, Fjerdingstad HB, Sandberg CJ, Behnan J, Glover JC, Langmoen IA, Stangeland B (2015)
Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo
Mol Cancer, 14, 121
DOI 10.1186/s12943-015-0398-x, PubMed 26081429

Mughal AA, Grieg Z, Skjellegrind H, Fayzullin A, Lamkhannat M, Joel M, Ahmed MS, Murrell W, Vik-Mo EO, Langmoen IA, Stangeland B (2015)
Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells
Mol Cancer, 14, 160
DOI 10.1186/s12943-015-0432-z, PubMed 26292663

Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA (2015)
Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells
Oncotarget, 6 (28), 26192-215
DOI 10.18632/oncotarget.4613, PubMed 26295306

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