Brain glial cells - a new target for future epilepsy treatment?
Kjell Heuser
Senior consultant and Head of translational epilepsy research within the Epilepsy Research Group of Oslo (ERGO), Kjell Heuser, recently pointed to the glial cells as a possible new target for epilepsy treatment in a reader's letter to the Journal of the Norwegian Medical Association. This was also commented on by the Norwegian Brain Council. The authors behind the post are besides Kjell Heuser (pictured), Rune Enger, Toni Berger and Erik Taubøll.
Tran V, Nguyen BTU, Krøigård T, Ulvin LB, Heuser K, Taubøll E, Rosenow F, Knake S, Strzelczyk A, Beier CP(2026) Cost of waiting: association of EEG delay and poor functional outcome in adult status epilepticus J Neurol Neurosurg Psychiatry, 97(10), 899-907 DOI 10.1136/jnnp-2026-338639, PubMed 42448462
Berger TC, Vigeland MD, Hjorthaug HS, Nome CG, Beier CP, Taubøll E, Selmer KK, Heuser K(2026) A stage-resolved neuron-glia transcriptional atlas reveals a glial inflammatory pivot in epilepsy Acta Neuropathol Commun, 14(1) DOI 10.1186/s40478-026-02323-w, PubMed 42324481
Bolle AE, Sarria-Estrada S, Bonduelle T, Dynesen BD, Toledo M, Che ZC, Heuser K, Lambertsen KL, Chatzikonstantinou A, Aupy J, Seneviratne U, Perez ES, Beier CP(2026) Peri-ictal magnetic resonance imaging abnormalities during status epilepticus in adults with idiopathic generalized epilepsy Epilepsy Behav, 180, 111050 DOI 10.1016/j.yebeh.2026.111050, PubMed 42000483