Gustavo Antonio De Souza
Publications 2023
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989
Use of adipose derived stem cells accelerates the healing process in third-degree burns
Burns, 50 (1), 132-145
DOI 10.1016/j.burns.2023.08.018, PubMed 37741785
Publications 2022
Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
Fluids Barriers CNS, 19 (1), 45
DOI 10.1186/s12987-022-00333-z, PubMed 35659255
The Expression of the Immunoproteasome Subunit PSMB9 Is Related to Distinct Molecular Subtypes of Uterine Leiomyosarcoma
Cancers (Basel), 14 (20)
DOI 10.3390/cancers14205007, PubMed 36291793
Publications 2021
Dermatological effects of Curcuma species: a systematic review
Clin Exp Dermatol, 46 (5), 825-833
DOI 10.1111/ced.14584, PubMed 33522006
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362
Publications 2020
EpitoCore: Mining Conserved Epitope Vaccine Candidates in the Core Proteome of Multiple Bacteria Strains
Front Immunol, 11, 816
DOI 10.3389/fimmu.2020.00816, PubMed 32431712
The Protein-Protein Interaction Network Reveals a Novel Role of the Signal Transduction Protein PII in the Control of c-di-GMP Homeostasis in Azospirillum brasilense
mSystems, 5 (6)
DOI 10.1128/mSystems.00817-20, PubMed 33144311
NAD+ biosynthesis in bacteria is controlled by global carbon/nitrogen levels via PII signaling
J Biol Chem, 295 (18), 6165-6176
DOI 10.1074/jbc.RA120.012793, PubMed 32179648
Publications 2019
Proteomic and Metabolomic Analysis of Azospirillum brasilensentrC Mutant under High and Low Nitrogen Conditions
J Proteome Res, 19 (1), 92-105
DOI 10.1021/acs.jproteome.9b00397, PubMed 31599156
On the Impact of the Pangenome and Annotation Discrepancies While Building Protein Sequence Databases for Bacteria Proteogenomics
Front Microbiol, 10, 1410
DOI 10.3389/fmicb.2019.01410, PubMed 31281302
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474
Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
J Neuroimmunol, 333, 576966
DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015
Publications 2018
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290
The SysteMHC Atlas project
Nucleic Acids Res, 46 (D1), D1237-D1247
DOI 10.1093/nar/gkx664, PubMed 28985418
A high-throughput pipeline for validation of antibodies
Nat Methods, 15 (11), 909-912
DOI 10.1038/s41592-018-0179-8, PubMed 30377371
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362
Publications 2017
Genome-wide identification of cancer/testis genes and their association with prognosis in a pan-cancer analysis
Oncotarget, 8 (54), 92966-92977
DOI 10.18632/oncotarget.21715, PubMed 29190970
Proteome analysis of an Escherichia coli ptsN-null strain under different nitrogen regimes
J Proteomics, 174, 28-35
DOI 10.1016/j.jprot.2017.12.006, PubMed 29274402
The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus
J Neurosurg, 129 (3), 829-837
DOI 10.3171/2017.4.JNS17284, PubMed 29053067
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470
A tool for integrating genetic and mass spectrometry-based peptide data: Proteogenomics Viewer: PV: A genome browser-like tool, which includes MS data visualization and peptide identification parameters
Bioessays, 39 (7)
DOI 10.1002/bies.201700015, PubMed 28582591
Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)
Proteomics, 17 (17-18)
DOI 10.1002/pmic.201600417, PubMed 28755400
Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death
Oncotarget, 8 (26), 43114-43129
DOI 10.18632/oncotarget.17810, PubMed 28562344
Publications 2016
Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
Sci Rep, 6, 25565
DOI 10.1038/srep25565, PubMed 27146306
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
J Proteome Res, 15 (10), 3841-3855
DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514
microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis
Mol Ther Nucleic Acids, 5 (10), e373
DOI 10.1038/mtna.2016.64, PubMed 27727249
MetaMass, a tool for meta-analysis of subcellular proteomics data
Nat Methods, 13 (10), 837-40
DOI 10.1038/nmeth.3967, PubMed 27571551
Label-free Proteomic Reveals that Cowpea Severe Mosaic Virus Transiently Suppresses the Host Leaf Protein Accumulation During the Compatible Interaction with Cowpea (Vigna unguiculata [L.] Walp.)
J Proteome Res, 15 (12), 4208-4220
DOI 10.1021/acs.jproteome.6b00211, PubMed 27934294
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
Kidney Int Rep, 2 (3), 461-469
DOI 10.1016/j.ekir.2016.11.005, PubMed 29142973
Dynamics of the Escherichia coli proteome in response to nitrogen starvation and entry into the stationary phase
Biochim Biophys Acta Proteins Proteom, 1865 (3), 344-352
DOI 10.1016/j.bbapap.2016.12.002, PubMed 27939605
Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment
Cancer Biol Ther, 17 (10), 1035-1050
DOI 10.1080/15384047.2016.1219813, PubMed 27636533
Publications 2015
Mechanisms underlying AQP4 accumulation in astrocyte endfeet
Glia, 63 (11), 2073-2091
DOI 10.1002/glia.22878, PubMed 26119521
Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog
Front Microbiol, 6, 6
DOI 10.3389/fmicb.2015.00006, PubMed 25713560
Intrathecal BCR transcriptome in multiple sclerosis versus other neuroinflammation: Equally diverse and compartmentalized, but more mutated, biased and overlapping with the proteome
Clin Immunol, 160 (2), 211-25
DOI 10.1016/j.clim.2015.06.001, PubMed 26055752
Label-free based quantitative proteomics analysis of primary neonatal porcine Leydig cells exposed to the persistent contaminant 3-methylsulfonyl-DDE
J Proteomics, 137, 68-82
DOI 10.1016/j.jprot.2015.12.007, PubMed 26691841
Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells
Mol Cell Proteomics, 15 (3), 1007-16
DOI 10.1074/mcp.M115.050138, PubMed 26637539
Publications 2014
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Immunogenetics, 67 (2), 73-84
DOI 10.1007/s00251-014-0819-9, PubMed 25502872
HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
J Immunol, 193 (9), 4497-506
DOI 10.4049/jimmunol.1301466, PubMed 25261484
Identification of rare alternative splicing events in MS/MS data reveals a significant fraction of alternative translation initiation sites
PeerJ, 2, e673
DOI 10.7717/peerj.673, PubMed 25405079
Characterization of amyloid in equine recurrent uveitis as AA amyloid
J Comp Pathol, 151 (2-3), 228-33
DOI 10.1016/j.jcpa.2014.04.007, PubMed 24975895
Assessing the citrullinome in rheumatoid arthritis synovial fluid with and without enrichment of citrullinated peptides
J Proteome Res, 13 (6), 2867-73
DOI 10.1021/pr500030x, PubMed 24724574
Nasal and ocular amyloidosis in a 15-year-old horse
Acta Vet Scand, 56 (1), 50
DOI 10.1186/s13028-014-0050-6, PubMed 25159190
Publications 2013
An approach for triplex-isobaric peptide termini labeling (triplex-IPTL)
Anal Chem, 85 (4), 2478-85
DOI 10.1021/ac3035508, PubMed 23316706
Publications 2011
Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway
J Proteomics, 75 (2), 502-10
DOI 10.1016/j.jprot.2011.08.016, PubMed 21920479
A proteomic view of mycobacteria
Proteomics, 11 (15), 3118-27
DOI 10.1002/pmic.201100043, PubMed 21726049
Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains
BMC Microbiol, 11, 18
DOI 10.1186/1471-2180-11-18, PubMed 21261938
Proteomic analysis of a multi-resistant clinical Escherichia coli isolate of unknown genomic background
J Proteomics, 75 (6), 1830-7
DOI 10.1016/j.jprot.2011.12.024, PubMed 22236517
A quantitative view on Mycobacterium leprae antigens by proteomics
J Proteomics, 74 (9), 1711-9
DOI 10.1016/j.jprot.2011.01.004, PubMed 21278007
Publications 2010
Proteogenomic analysis of polymorphisms and gene annotation divergences in prokaryotes using a clustered mass spectrometry-friendly database
Mol Cell Proteomics, 10 (1), M110.002527
DOI 10.1074/mcp.M110.002527, PubMed 21030493
MSMSpdbb: providing protein databases of closely related organisms to improve proteomic characterization of prokaryotic microbes
Bioinformatics, 26 (5), 698-9
DOI 10.1093/bioinformatics/btq004, PubMed 20080508
Using a label-free proteomics method to identify differentially abundant proteins in closely related hypo- and hypervirulent clinical Mycobacterium tuberculosis Beijing isolates
Mol Cell Proteomics, 9 (11), 2414-23
DOI 10.1074/mcp.M900422-MCP200, PubMed 20190197
Proteomic Approaches to Study Immunity in Infection
Methods Microbiol., 37, 101-114
DOI 10.1016/S0580-9517(10)37005-X
Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv
BMC Microbiol, 10, 132
DOI 10.1186/1471-2180-10-132, PubMed 20429878
Analysis of detergent-insoluble and whole cell lysate fractions of resting neutrophils using high-resolution mass spectrometry
J Proteome Res, 9 (4), 2030-6
DOI 10.1021/pr1000253, PubMed 20158270
Publications 2009
Insulin-degrading enzyme binds to the nonglycosylated precursor of varicella-zoster virus gE protein found in the endoplasmic reticulum
J Virol, 84 (2), 847-55
DOI 10.1128/JVI.01801-09, PubMed 19864391
Validating divergent ORF annotation of the Mycobacterium leprae genome through a full translation data set and peptide identification by tandem mass spectrometry
Proteomics, 9 (12), 3233-43
DOI 10.1002/pmic.200800955, PubMed 19562797
The Impact of Proteomic Advances on Bacterial Gene Annotation
Curr. Proteomics, 6 (2), 84-92
DOI 10.2174/157016409788680947
Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods
Microbiology (Reading), 155 (Pt 7), 2375-2383
DOI 10.1099/mic.0.025270-0, PubMed 19389770
HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells
Scand J Immunol, 70 (3), 264-76
DOI 10.1111/j.1365-3083.2009.02299.x, PubMed 19703016
Proteomic analysis of total cellular proteins of human neutrophils
Proteome Sci, 7, 32
DOI 10.1186/1477-5956-7-32, PubMed 19719850
Publications 2008
High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example
BMC Genomics, 9, 316
DOI 10.1186/1471-2164-9-316, PubMed 18597682
Membrane and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies
Proteomics, 8 (9), 1859-70
DOI 10.1002/pmic.200700528, PubMed 18442171
Publications 2006
Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system
Genome Biol, 7 (6), R50
DOI 10.1186/gb-2006-7-6-r50, PubMed 16784548
Identification of 491 proteins in the tear fluid proteome reveals a large number of proteases and protease inhibitors
Genome Biol, 7 (8), R72
DOI 10.1186/gb-2006-7-8-R72, PubMed 16901338
Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation
Proteomics, 6 (5), 1460-70
DOI 10.1002/pmic.200500243, PubMed 16429458
Publications 2003
Amino acid sequence and tertiary structure of Cratylia mollis seed lectin
Glycobiology, 13 (12), 961-72
DOI 10.1093/glycob/cwg115, PubMed 12966038
Publications 2000
Effect of brown spider venom on basement membrane structures
Histochem J, 32 (7), 397-408
DOI 10.1023/a:1004031019827, PubMed 10987503