About the group
The clinical effectiveness group at the University of Oslo and Oslo University Hospital was established in 2012 by Michael Bretthauer and Mette Kalager. The young and dynamic group performs top research in diagnostic and therapeutic interventions in several clinical areas. The current portfolio of the group includes more than 300,000 patients in clinical trials. In addition, the group runs large observational studies and tests new new statistical methods in medicine.
Signature studies of the group include the Norwegian Colorectal Cancer Prevention trial NORCCAP, the Nordic-European Initiative on Colorectal Cancer NordICC, and the European Polyp Surveillance trials EPoS.
The group wants to move barriers in clinical research and aims at improving clinical practices. The work is team-based and inclusive. Click here for news and publications.
News
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Uncertain Impact of AI in Colorectal Cancer Screening Mar. 28, 2025 10:52 AM
A team of Norwegian researchers, through international collaboration, found that the use of artificial intelligence (AI) during colonoscopy increased the detection of polyps by about 8%, but the risk of cancer was minimally affected.
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AI-assisted colonoscopy could reduce overtreatment and costs Feb. 27, 2025 9:47 PM
PhD fellow Natalie Halvorsen published a paper on AI-assisted colonoscopy in this week's Endoscopy journal. The paper investigates the cost-effectiveness of leaving harmless polyps in the colon when adding AI as a decision-making tool.
Funding
The group receives research grants from many entitiescome out their amongst the Norwegian research Council, the European Union, the Norwegian cancer society, the southeast NORWAY health region, and others.
Collaboration
Collaboration: the group is running the regional network for clinical effectiveness in gastroenterology in South-East Norway which is a collaboration between researchers at Oslo University Hospital and the University of Oslo, Sørlandet Hospital in Arendal and Kristiansand, Telemark Hospital, Vestfold Hospital, Bærum Hospital Vestre Viken, Østfold Hospital and Innlandet Hospital.
The research group has a formal collaboration with these and other academic institutions abroad:
- Harvard T.H Chan School of Public Health, Boston, USA
- Karolinska Instituttet, Stockholm, Sweden
- Erasmus Medical Centre, Rotterdam, Netherlands
- Marie Curie Sklodowska Cancer Center, Warsawa, Poland
- Sloan Kettering Memorial Cancer Center, New York City, USA
- Uppsala University Hospital, Uppsala, Sweden
- Landspitali University Hospital, Reykjavik, Iceland
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Showa University Northern Yokohama Hospital, Yokohama
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King’s College Hospital, London