Cardiac Intensive Care Research Unit (CICRU)
Geir Ø. Andersen
Main aim:
Clinical heart research with translational aspects focusing on patients with acute ST-elevation myocardial infarction (STEMI) or cardiac arrest admitted to the cardiac intensive care unit (CICU).
Primary objectives:
- To explore in detail the pathogenesis of acute coronary syndromes ((ACS) including STEMI) and ischemia-reperfusion injury with focus on how systemic and local inflammation may potentially contribute to plaque destabilization and myocardial damage.
- Interventional studies targeting ischemia/reperfusion injury aiming to reduce infarct size
- Treatment of acute heart failure and cardiogenic shock complicating STEMI
- Prognostication, monitoring and treatment of patients with out-of- hospital cardiac arrest in order to improve survival and neurological prognosis
- Obtain new mechanistic insights on the importance of residual inflammation on patients with ACS, open the way for novel treatment and prevention options