Publications, Clinical and Experimental Pathology

Publications 2025

Asphaug L, Akslen LA, Blix ES, Boge B, Borgen EF, Brekke MB, Falk RS, Geitvik GA, Gilje B, Gravdehaug B, Heie A, Janssen E, Kiserud CE, Kursetgjerde T, Langerød A, Lømo J, Mannsåker B, Mortensen E, Olsson P, Porojnicu AC, Raj SX, Roe OD, Russnes HEG, Skjerven HK, Songe-Møller S et al. (2025)
Cost-effectiveness of Prosigna for Adjuvant Treatment Decisions in Early Breast Cancer: Healthcare Sector and Societal Perspectives
Clin Breast Cancer (in press)
DOI 10.1016/j.clbc.2025.04.011, PubMed 40348620

Bergholtz H, Norum JH, Lien TG, Skrede ML, Garred Ø, Sørlie T (2025)
B cells and energy metabolism in HER2-positive DCIS: insights into breast cancer progression from spatial-omics analyses
Breast Cancer Res, 27 (1), 44
DOI 10.1186/s13058-025-01990-2, PubMed 40119362

Publications 2024

Andresen NK, Røssevold AH, Borgen E, Schirmer CB, Gilje B, Garred Ø, Lømo J, Stensland M, Nordgård O, Falk RS, Mathiesen RR, Russnes HG, Kyte JA, Naume B (2024)
Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors - a biomarker analysis of the ALICE and ICON trials
Mol Oncol (in press)
DOI 10.1002/1878-0261.13675, PubMed 38978352

Andresen NK, Røssevold AH, Quaghebeur C, Gilje B, Boge B, Gombos A, Falk RS, Mathiesen RR, Julsrud L, Garred Ø, Russnes HG, Lereim RR, Chauhan SK, Lingjærde OC, Dunn C, Naume B, Kyte JA (2024)
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720

Eide NA, Faber RT, Garred Ø, Sørum Falk R, Robsahm TE (2024)
Characterizations of uveal melanoma patients with three additional primary malignancies
Acta Ophthalmol, 102 (6), 690-696
DOI 10.1111/aos.16631, PubMed 38229427

Kildal W, Cyll K, Kalsnes J, Islam R, Julbø FM, Pradhan M, Ersvær E, Shepherd N, Vlatkovic L, OSBREAC, Tekpli X, Garred Ø, Kristensen GB, Askautrud HA, Hveem TS, Danielsen HE, OSBREAC - Oslo Breast Cancer Consortium (2024)
Deep learning for automated scoring of immunohistochemically stained tumour tissue sections - Validation across tumour types based on patient outcomes
Heliyon, 10 (13), e32529
DOI 10.1016/j.heliyon.2024.e32529, PubMed 39040241

Ohnstad HO, Blix ES, Akslen LA, Gilje B, Raj SX, Skjerven H, Borgen E, Janssen EAM, Mortensen E, Brekke MB, Falk RS, Schlichting E, Boge B, Songe-Møller S, Olsson P, Heie A, Mannsåker B, Vestlid MA, Kursetgjerde T, Gravdehaug B, Suhrke P, Sanchez E, Bublevic J, Røe OD, Geitvik GA et al. (2024)
Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer-a prospective national multicentre study (EMIT-1)
ESMO Open, 9 (6), 103475
DOI 10.1016/j.esmoop.2024.103475, PubMed 38838499

Udjus C, Halvorsen B, Kong XY, Sagen EL, Martinsen M, Yang K, Løberg EM, Christensen G, Skjønsberg OH, Larsen KO (2024)
Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs
Physiol Rep, 12 (14), e16143
DOI 10.14814/phy2.16143, PubMed 39034131

Viktil E, Hanekamp BA, Nesbakken A, Løberg EM, Sjo OH, Negård A, Dormagen JB, Schulz A (2024)
Early rectal cancer: The diagnostic performance of MRI supplemented with a rectal micro-enema and a modified staging system to identify tumors eligible for local excision
Acta Radiol Open, 13 (5), 20584601241241523
DOI 10.1177/20584601241241523, PubMed 38645439

Viktil E, Hanekamp BA, Nesbakken A, Løberg EM, Sjo OH, Negård A, Dormagen JB, Schulz A (2024)
MRI of early rectal cancer; bisacodyl micro-enema increases submucosal width, reader confidence, and tumor conspicuity
Abdom Radiol (NY), 50 (6), 2401-2413
DOI 10.1007/s00261-024-04701-1, PubMed 39645641

Publications 2023

Navaratnam J, Faber R, Eide N, Lund-Iversen M, Garred Ø, Munier FL (2023)
Retinocytoma Undergoing Retinoblastoma Transformation in an Adult Patient
Case Rep Ophthalmol Med, 2023, 8127245
DOI 10.1155/2023/8127245, PubMed 37529687

Publications 2022

Brunvoll SH, Flote VG, Halset EH, Bertheussen GF, Skjerven H, Lømo J, Thune I, Hjartåker A (2022)
Normal and unusual days for dietary intake during the 12 months after a breast cancer diagnosis in women
Eur J Nutr, 61 (8), 3873-3885
DOI 10.1007/s00394-022-02925-9, PubMed 35750881

Røssevold AH, Andresen NK, Bjerre CA, Gilje B, Jakobsen EH, Raj SX, Falk RS, Russnes HG, Jahr T, Mathiesen RR, Lømo J, Garred Ø, Chauhan SK, Lereim RR, Dunn C, Naume B, Kyte JA (2022)
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103

Publications 2021

Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021

Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
JCO Precis Oncol, 5
DOI 10.1200/PO.20.00086, PubMed 34036235

Krüger K, Silwal-Pandit L, Wik E, Straume O, Stefansson IM, Borgen E, Garred Ø, Naume B, Engebraaten O, Akslen LA (2021)
Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
Sci Rep, 11 (1), 3388
DOI 10.1038/s41598-021-81914-0, PubMed 33564016

Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228

Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred Ø, Riis ML, Osbreac, Lingjaerde OC, Myklebust JH, Russnes HG (2021)
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864

Talwelkar SS, Mäyränpää MI, Søraas L, Potdar S, Bao J, Hemmes A, Linnavirta N, Lømo J, Räsänen J, Knuuttila A, Wennerberg K, Verschuren EW (2021)
Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
Cell Rep Med, 2 (8), 100373
DOI 10.1016/j.xcrm.2021.100373, PubMed 34467250

Publications 2020

Brunvoll SH, Thune I, Bertheussen GF, Fjeldheim F, Flote VG, Frydenberg H, Lundgren S, Skjerven H, Lømo J, Fagerland MW, McTiernan A, Schlichting E, Hjartåker A (2020)
Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery
Br J Nutr, 125 (2), 172-182
DOI 10.1017/S0007114520002627, PubMed 32811572

Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R (2020)
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187

Hauge T, Franco-Lie I, Løberg EM, Hauge T, Johnson E (2020)
Outcome after endoscopic treatment for dysplasia and superficial esophageal cancer - a cohort study
Scand J Gastroenterol, 55 (9), 1132-1138
DOI 10.1080/00365521.2020.1800813, PubMed 32748653

Ness C, Katta K, Garred Ø, Kumar T, Olstad OK, Petrovski G, Moe MC, Noer A (2020)
Integrated differential DNA methylation and gene expression of formalin-fixed paraffin-embedded uveal melanoma specimens identifies genes associated with early metastasis and poor prognosis
Exp Eye Res, 203, 108426
DOI 10.1016/j.exer.2020.108426, PubMed 33387485

Sarna VK, Lunding J, Loberg EM, Solberg IC (2020)
A man in his 50s with chronic diarrhea and weight loss
Tidsskr. Nor. Laegeforen., 140 (11), 1148-1151

Sarna VK, Lunding J, Løberg EM, Solberg IC (2020)
[A man in his fifties with chronic diarrhoea and weight loss]
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.19.0812, PubMed 32815334

Sondén ECB, Sebuødegård S, Korvald C, Lømo J, Schlichting E, Brandal SHB, Hofvind S (2020)
[Cosmetic breast implants and breast cancer]
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0266, PubMed 32105043

Sondén ECB, Sebuødegård S, Korvald C, Lømo J, Schlichting E, Brandal SHB, Hofvind S (2020)
[Correction: Cosmetic breast implants and breast cancer]
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.20.0163, PubMed 32192257

Tinholt M, Stavik B, Tekpli X, Garred Ø, Borgen E, Kristensen V, Sahlberg KK, Sandset PM, Iversen N (2020)
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104

von der Lippe Gythfeldt H, Lien T, Tekpli X, Silwal-Pandit L, Borgen E, Garred Ø, Skjerven H, Schlichting E, Lundgren S, Wist E, Naume B, Kristensen V, Børresen-Dale AL, Lingjaerde OC, Engebraaten O (2020)
Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer
Int J Cancer, 147 (9), 2515-2525
DOI 10.1002/ijc.33108, PubMed 32488909

Wood TR, Gundersen JK, Falck M, Maes E, Osredkar D, Løberg EM, Sabir H, Walløe L, Thoresen M (2020)
Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic-ischaemic brain injury: a single laboratory meta-analysis
Sci Rep, 10 (1), 10833
DOI 10.1038/s41598-020-67532-2, PubMed 32616806

Publications 2019

Debik J, Euceda LR, Lundgren S, Gythfeldt HVL, Garred Ø, Borgen E, Engebraaten O, Bathen TF, Giskeødegård GF (2019)
Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients
J Proteome Res, 18 (10), 3649-3660
DOI 10.1021/acs.jproteome.9b00316, PubMed 31483662

Johansson HJ, Socciarelli F, Vacanti NM, Haugen MH, Zhu Y, Siavelis I, Fernandez-Woodbridge A, Aure MR, Sennblad B, Vesterlund M, Branca RM, Orre LM, Huss M, Fredlund E, Beraki E, Garred Ø, Boekel J, Sauer T, Zhao W, Nord S, Höglander EK, Jans DC, Brismar H, Haukaas TH, Bathen TF et al. (2019)
Breast cancer quantitative proteome and proteogenomic landscape
Nat Commun, 10 (1), 1600
DOI 10.1038/s41467-019-09018-y, PubMed 30962452

Lai X, Geier OM, Fleischer T, Garred Ø, Borgen E, Funke SW, Kumar S, Rognes ME, Seierstad T, Børresen-Dale AL, Kristensen VN, Engebraaten O, Köhn-Luque A, Frigessi A (2019)
Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Cancer Res, 79 (16), 4293-4304
DOI 10.1158/0008-5472.CAN-18-1804, PubMed 31118201

Nome ME, Euceda LR, Jabeen S, Debik J, Bathen TF, Giskeødegård GF, Taskén KA, Maelandsmo GM, Halvorsen B, Yndestad A, Borgen E, Garred Ø, Aukrust P, Ueland T, Engebraaten O, Kristensen VN, Tekpli X (2019)
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972

Panagopoulos I, Gorunova L, Andersen HK, Pedersen TD, Lømo J, Lund-Iversen M, Micci F, Heim S (2019)
Genetic Characterization of Myoid Hamartoma of the Breast
Cancer Genomics Proteomics, 16 (6), 563-568
DOI 10.21873/cgp.20158, PubMed 31659109

Tekpli X, Lien T, Røssevold AH, Nebdal D, Borgen E, Ohnstad HO, Kyte JA, Vallon-Christersson J, Fongaard M, Due EU, Svartdal LG, Sveli MAT, Garred Ø, OSBREAC, Frigessi A, Sahlberg KK, Sørlie T, Russnes HG, Naume B, Kristensen VN (2019)
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750

Publications 2018

Hofvind S, Hovda T, Holen ÅS, Lee CI, Albertsen J, Bjørndal H, Brandal SHB, Gullien R, Lømo J, Park D, Romundstad L, Suhrke P, Vigeland E, Skaane P (2018)
Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Digital Mammography: Evaluation in a Population-based Screening Program
Radiology, 287 (3), 787-794
DOI 10.1148/radiol.2018171361, PubMed 29494322

Huun MU, Garberg H, Løberg EM, Escobar J, Martinez-Orgado J, Saugstad OD, Solberg R (2018)
DHA and therapeutic hypothermia in a short-term follow-up piglet model of hypoxia-ischemia: Effects on H+MRS biomarkers
PLoS One, 13 (8), e0201895
DOI 10.1371/journal.pone.0201895, PubMed 30086156

Höglander EK, Nord S, Wedge DC, Lingjærde OC, Silwal-Pandit L, Gythfeldt HV, Vollan HKM, Fleischer T, Krohn M, Schlitchting E, Borgen E, Garred Ø, Holmen MM, Wist E, Naume B, Van Loo P, Børresen-Dale AL, Engebraaten O, Kristensen V (2018)
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
Genome Med, 10 (1), 92
DOI 10.1186/s13073-018-0601-y, PubMed 30497530

Madssen TS, Thune I, Flote VG, Lundgren S, Bertheussen GF, Frydenberg H, Wist E, Schlichting E, Schäfer H, Fjøsne HE, Vettukattil R, Lømo J, Bathen TF, Giskeødegård GF (2018)
Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment
Br J Cancer, 119 (9), 1144-1154
DOI 10.1038/s41416-018-0211-x, PubMed 30401977

Samardzic T, Lømo J, Skaane P (2018)
Screening-detected desmoid tumor of the breast: findings at conventional imaging and digital breast tomosynthesis
Acta Radiol Open, 7 (1), 2058460117752034
DOI 10.1177/2058460117752034, PubMed 29375894

Tinholt M, Garred Ø, Borgen E, Beraki E, Schlichting E, Kristensen V, Sahlberg KK, Iversen N (2018)
Subtype-specific clinical and prognostic relevance of tumor-expressed F5 and regulatory F5 variants in breast cancer: the CoCaV study
J Thromb Haemost, 16 (7), 1347-1356
DOI 10.1111/jth.14151, PubMed 29766637

Westvik ÅS, Weedon-Fekjær H, Mæhlen J, Liestøl K (2018)
Evaluating different breast tumor progression models using screening data
BMC Cancer, 18 (1), 209
DOI 10.1186/s12885-018-4130-2, PubMed 29463227

Publications 2017

Brusletto BS, Hellerud BC, Løberg EM, Goverud IL, Vege Å, Berg JP, Brandtzaeg P, Øvstebø R (2017)
Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease
BMC Clin Pathol, 17, 10
DOI 10.1186/s12907-017-0049-9, PubMed 28824331

Euceda LR, Haukaas TH, Giskeodegard GF, Vettukattil R, Engel J, Silwal-Pandit L, Lundgren S, Borgen E, Garred O, Postma G, Buydens LMC, Borresen-Dale AL, Engebraaten O, Bathen TF (2017)
Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
Metabolomics, 13 (4), 37
DOI 10.1007/s11306-017-1168-0

Garberg HT, Solberg R, Barlinn J, Martinez-Orgado J, Løberg EM, Saugstad OD (2017)
High-Dose Cannabidiol Induced Hypotension after Global Hypoxia-Ischemia in Piglets
Neonatology, 112 (2), 143-149
DOI 10.1159/000471786, PubMed 28564654

Ness C, Garred Ø, Eide NA, Kumar T, Olstad OK, Bærland TP, Petrovski G, Moe MC, Noer A (2017)
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs
Mol Vis, 23, 680-694
PubMed 29033534

Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlitchting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen V, Langerød A, Lundgren S, Wist E, Naume B, Lingjærde OC, Børresen-Dale AL et al. (2017)
The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
Clin Cancer Res, 23 (16), 4662-4670
DOI 10.1158/1078-0432.CCR-17-0160, PubMed 28487444

Vaysse C, Lomo J, Garred O, Fjeldheim F, Lofteroed T, Schlichting E, McTiernan A, Frydenberg H, Husoy A, Lundgren S, Fagerland MW, Richardsen E, Wist EA, Muller C, Thune I (2017)
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer (vol 3, 35, 2017)
npj Breast Cancer, 3, 35
DOI 10.1038/s41523-017-0030-x

Vaysse C, Lømo J, Garred Ø, Fjeldheim F, Lofteroed T, Schlichting E, McTiernan A, Frydenberg H, Husøy A, Lundgren S, Fagerland MW, Richardsen E, Wist EA, Muller C, Thune I (2017)
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer
NPJ Breast Cancer, 3, 19
DOI 10.1038/s41523-017-0015-9, PubMed 28649659

Vaysse C, Lømo J, Garred Ø, Fjeldheim F, Lofteroed T, Schlichting E, McTiernan A, Frydenberg H, Husøy A, Lundgren S, Fagerland MW, Richardsen E, Wist EA, Muller C, Thune I (2017)
Erratum: Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer
NPJ Breast Cancer, 3, 35
DOI 10.1038/s41523-017-0030-x, PubMed 28884144

Wood T, Hobbs C, Falck M, Brun AC, Løberg EM, Thoresen M (2017)
Rectal temperature in the first five hours after hypoxia-ischemia critically affects neuropathological outcomes in neonatal rats
Pediatr Res, 83 (2), 536-544
DOI 10.1038/pr.2017.51, PubMed 28288145

Publications 2016

Austdal LP, Mathisen GH, Løberg EM, Paulsen RE (2016)
Calcium-induced apoptosis of developing cerebellar granule neurons depends causally on NGFI-B
Int J Dev Neurosci, 55, 82-90
DOI 10.1016/j.ijdevneu.2016.10.003, PubMed 27769911

Flote VG, Vettukattil R, Bathen TF, Egeland T, McTiernan A, Frydenberg H, Husøy A, Finstad SE, Lømo J, Garred Ø, Schlichting E, Wist EA, Thune I (2016)
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer
Lipids Health Dis, 15, 56
DOI 10.1186/s12944-016-0225-4, PubMed 26970778

Garberg HT, Huun MU, Escobar J, Martinez-Orgado J, Løberg EM, Solberg R, Didrik Saugstad O (2016)
Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets
Pediatr Res, 80 (5), 710-718
DOI 10.1038/pr.2016.149, PubMed 27441365

Grøtting MS, Løberg EM, Johannessen HO, Johnson E (2016)
Resection for oesophageal cancer - complications and survival
Tidsskr Nor Laegeforen, 136 (9), 809-13
DOI 10.4045/tidsskr.15.1136, PubMed 27221180

Haukaas TH, Euceda LR, Giskeødegård GF, Lamichhane S, Krohn M, Jernström S, Aure MR, Lingjærde OC, Schlichting E, Garred Ø, Due EU, Mills GB, Sahlberg KK, Børresen-Dale AL, Bathen TF, Oslo Breast Cancer Consortium (OSBREAC) (2016)
Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
Cancer Metab, 4, 12
DOI 10.1186/s40170-016-0152-x, PubMed 27350877

Nesset CK, Kong XY, Damme M, Schjalm C, Roos N, Løberg EM, Eskild W (2016)
Age-dependent development of liver fibrosis in Glmp (gt/gt) mice
Fibrogenesis Tissue Repair, 9, 5
DOI 10.1186/s13069-016-0042-4, PubMed 27141234

Shlien A, Raine K, Fuligni F, Arnold R, Nik-Zainal S, Dronov S, Mamanova L, Rosic A, Ju YS, Cooke SL, Ramakrishna M, Papaemmanuil E, Davies HR, Tarpey PS, Van Loo P, Wedge DC, Jones DR, Martin S, Marshall J, Anderson E, Hardy C, ICGC Breast Cancer Working Group, Oslo Breast Cancer Research Consortium, Barbashina V, Aparicio SA, Sauer T et al. (2016)
Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
Cell Rep, 16 (7), 2032-46
DOI 10.1016/j.celrep.2016.07.028, PubMed 27498871

Tinholt M, Sandset PM, Mowinckel MC, Garred Ø, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Jacobsen AF, Skretting G, Iversen N (2016)
Determinants of acquired activated protein C resistance and D-dimer in breast cancer
Thromb Res, 145, 78-83
DOI 10.1016/j.thromres.2016.08.003, PubMed 27505249

Publications 2015

Cero FT, Hillestad V, Sjaastad I, Yndestad A, Aukrust P, Ranheim T, Lunde IG, Olsen MB, Lien E, Zhang L, Haugstad SB, Løberg EM, Christensen G, Larsen KO, Skjønsberg OH (2015)
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556

Dahlberg D, Mariussen E, Goverud IL, Tønjum T, Mæhlen J, Antal EA, Hassel B (2015)
Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
Neurotoxicology, 48, 61-7
DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835

Eide N, Garred Ø, Beiske K, Fodstad Ø (2015)
Bilateral uveal melanomas with different gene expression detected with 7 years interval
Acta Ophthalmol, 94 (1), 99-102
DOI 10.1111/aos.12857, PubMed 26496992

Kumar NT, Liestøl K, Løberg EM, Reims HM, Mæhlen J (2015)
Apolipoprotein E allelotype is associated with neuropathological findings in Alzheimer's disease
Virchows Arch, 467 (2), 225-35
DOI 10.1007/s00428-015-1772-1, PubMed 25898889

Young VS, Viktil E, Løberg EM, Enden T (2015)
Benign metastasizing pleomorphic adenoma in liver mimicking synchronic metastatic disease from colorectal cancer: a case report with emphasis on imaging findings
Acta Radiol Open, 4 (8), 2058460115594199
DOI 10.1177/2058460115594199, PubMed 26331091

Ystgaard MB, Sejersted Y, Løberg EM, Lien E, Yndestad A, Saugstad OD (2015)
Early Upregulation of NLRP3 in the Brain of Neonatal Mice Exposed to Hypoxia-Ischemia: No Early Neuroprotective Effects of NLRP3 Deficiency
Neonatology, 108 (3), 211-9
DOI 10.1159/000437247, PubMed 26279061

Zahl PH, Mæhlen J (2015)
Bias in Observational Studies of the Association between Menopausal Hormone Therapy and Breast Cancer
PLoS One, 10 (5), e0124076
DOI 10.1371/journal.pone.0124076, PubMed 25938446

Aarås AM, Reitan-Gjersøe TA, Waage A, Mala T, Edwin B, Løberg EM, Abildgaard A, Røsok BI (2015)
Laparoscopic resection of recurrent ectopic hepatocellular carcinoma: A case report with review of the literature and guidelines for follow-up
Int J Surg Case Rep, 17, 92-5
DOI 10.1016/j.ijscr.2015.10.014, PubMed 26590353

Publications 2014

Chen Y, Klingen TA, Wik E, Aas H, Vigeland E, Liestøl K, Garred Ø, Mæhlen J, Akslen LA, Lømo J (2014)
Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study
Diagn Pathol, 9, 230
DOI 10.1186/s13000-014-0230-8, PubMed 25522915

Eide NA, Baerland TP, Sauesund E, Lømo J, Lund-Iversen M, Liestøl S (2014)
Relapse of acute lymphoblastic leukaemia (ALL)
Acta Ophthalmol, 93 (5), e395-e396
DOI 10.1111/aos.12619, PubMed 25495443

Hassel B, Dahlberg D, Mariussen E, Goverud IL, Antal EA, Tønjum T, Maehlen J (2014)
Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
J Neurosci Res, 92 (12), 1792-800
DOI 10.1002/jnr.23444, PubMed 25043715

Holme Ø, Bretthauer M, Eide TJ, Løberg EM, Grzyb K, Løberg M, Kalager M, Adami HO, Kjellevold Ø, Hoff G (2014)
Long-term risk of colorectal cancer in individuals with serrated polyps
Gut, 64 (6), 929-36
DOI 10.1136/gutjnl-2014-307793, PubMed 25399542

Hugdahl K, Craven AR, Nygård M, Løberg EM, Berle JØ, Johnsen E, Kroken R, Specht K, Andreassen OA, Ersland L (2014)
Glutamate as a mediating transmitter for auditory hallucinations in schizophrenia: a (1)H MRS study
Schizophr Res, 161 (2-3), 252-60
DOI 10.1016/j.schres.2014.11.015, PubMed 25542859

Kong XY, Nesset CK, Damme M, Løberg EM, Lübke T, Mæhlen J, Andersson KB, Lorenzo PI, Roos N, Thoresen GH, Rustan AC, Kase ET, Eskild W (2014)
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
Dis Model Mech, 7 (3), 351-62
DOI 10.1242/dmm.014050, PubMed 24487409

Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022

Publications 2013

Kumar NT, Liestøl K, Løberg EM, Reims HM, Mæhlen J (2013)
Postmortem heart weight: relation to body size and effects of cardiovascular disease and cancer
Cardiovasc Pathol, 23 (1), 5-11
DOI 10.1016/j.carpath.2013.09.001, PubMed 24121021

Mathisen GH, Yazdani M, Rakkestad KE, Aden PK, Bodin J, Samuelsen M, Nygaard UC, Goverud IL, Gaarder M, Løberg EM, Bølling AK, Becher R, Paulsen RE (2013)
Prenatal exposure to bisphenol A interferes with the development of cerebellar granule neurons in mice and chicken
Int J Dev Neurosci, 31 (8), 762-9
DOI 10.1016/j.ijdevneu.2013.09.009, PubMed 24091367

Puchades M, Sogn CJ, Maehlen J, Bergersen LH, Gundersen V (2013)
Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease
J Parkinsons Dis, 3 (3), 371-85
DOI 10.3233/JPD-130190, PubMed 23963315

von Volkmann HL, Havre RF, Løberg EM, Haaland T, Immervoll H, Haukeland JW, Hausken T, Gilja OH (2013)
Quantitative measurement of ultrasound attenuation and Hepato-Renal Index in Non-Alcoholic Fatty Liver Disease
Med Ultrason, 15 (1), 16-22
DOI 10.11152/mu.2013.2066.151.hlv1qmu2, PubMed 23486619

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083

Publications 2012

Alfsen GC, Mæhlen J (2012)
The value of autopsies for determining the cause of death
Tidsskr Nor Laegeforen, 132 (2), 147-51
DOI 10.4045/tidsskr.11.0427, PubMed 22278269

Cero FT, Hillestad V, Løberg EM, Christensen G, Larsen KO, Skjønsberg OH (2012)
IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung
Exp Lung Res, 38 (8), 406-19
DOI 10.3109/01902148.2012.716903, PubMed 22908875

Dalen ML, Liu X, Elstad M, Løberg EM, Saugstad OD, Rootwelt T, Thoresen M (2012)
Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat
Pediatr Res, 71 (3), 247-52
DOI 10.1038/pr.2011.43, PubMed 22337259

Kumar NT, Liestøl K, Løberg EM, Reims HM, Brorson SH, Maehlen J (2012)
The apolipoprotein E polymorphism and cardiovascular diseases--an autopsy study
Cardiovasc Pathol, 21 (6), 461-9
DOI 10.1016/j.carpath.2012.02.005, PubMed 22440829

Lannerstedt H, Konopski Z, Sandvik L, Haaland T, Løberg EM, Haukeland JW (2012)
Combining transient elastography with FIB4 enhances sensitivity in detecting advanced fibrosis of the liver
Scand J Gastroenterol, 48 (1), 93-100
DOI 10.3109/00365521.2012.746389, PubMed 23205894

Suhrke P, Mæhlen J, Zahl PH (2012)
Hormone therapy use and breast cancer incidence by histological subtypes in Sweden and Norway
Breast J, 18 (6), 549-56
DOI 10.1111/tbj.12001, PubMed 23002918

Zahl PH, Mæhlen J (2012)
Overdiagnosis of breast cancer after 14 years of mammography screening
Tidsskr Nor Laegeforen, 132 (4), 414-7
DOI 10.4045/tidsskr.11.0195, PubMed 22353833

Publications 2011

Aden P, Paulsen RE, Mæhlen J, Løberg EM, Goverud IL, Liestøl K, Lømo J (2011)
Glucocorticoids dexamethasone and hydrocortisone inhibit proliferation and accelerate maturation of chicken cerebellar granule neurons
Brain Res, 1418, 32-41
DOI 10.1016/j.brainres.2011.08.053, PubMed 21925649

Brottveit M, Ráki M, Bergseng E, Fallang LE, Simonsen B, Løvik A, Larsen S, Løberg EM, Jahnsen FL, Sollid LM, Lundin KE (2011)
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548

de Lange C, Brabrand K, Emblem KE, Bjornerud A, Løberg EM, Saugstad OD, Munkeby BH (2011)
Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs
Invest Radiol, 46 (11), 686-96
DOI 10.1097/RLI.0b013e3182266431, PubMed 21730873

Gøtzsche PC, Jørgensen KJ, Zahl PH, Mæhlen J (2011)
Why mammography screening has not lived up to expectations from the randomised trials
Cancer Causes Control, 23 (1), 15-21
DOI 10.1007/s10552-011-9867-8, PubMed 22072221

Haukeland JW, Dahl TB, Yndestad A, Gladhaug IP, Løberg EM, Haaland T, Konopski Z, Wium C, Aasheim ET, Johansen OE, Aukrust P, Halvorsen B, Birkeland KI (2011)
Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
DOI 10.1530/EJE-11-0864, PubMed 22170794

Johnsen E, Kroken R, Løberg EM, Kjelby E, Jørgensen HA (2011)
Sexual dysfunction and hyperprolactinemia in male psychotic inpatients: a cross-sectional study
Adv Urol, 2011, 686924
DOI 10.1155/2011/686924, PubMed 22190916

Larsen KO, Yndestad A, Sjaastad I, Løberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjønsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626

Lassen B, Helseth E, Rønning P, Scheie D, Johannesen TB, Mæhlen J, Langmoen IA, Meling TR (2011)
Surgical mortality at 30 days and complications leading to recraniotomy in 2630 consecutive craniotomies for intracranial tumors
Neurosurgery, 68 (5), 1259-68; discussion 1268-9
DOI 10.1227/NEU.0b013e31820c0441, PubMed 21273920

Slettedal JK, Nilssen DOV, Magelssen M, Loberg EM, Maehlen J (2011)
RESPONSE
Neuropathology, 31 (3), 307-308
DOI 10.1111/j.1440-1789.2011.01208.x

Suhrke P, Mæhlen J, Schlichting E, Jørgensen KJ, Gøtzsche PC, Zahl PH (2011)
Effect of mammography screening on surgical treatment for breast cancer in Norway: comparative analysis of cancer registry data
BMJ, 343, d4692
DOI 10.1136/bmj.d4692, PubMed 21914765

Tveito K, Hetta AK, Askedal M, Brunborg C, Sandvik L, Løberg EM, Skar V (2011)
Follow-up of coeliac disease with the novel one-hour 13C-sorbitol breath test versus the H2-sorbitol breath test
Scand J Gastroenterol, 46 (7-8), 837-43
DOI 10.3109/00365521.2011.575175, PubMed 21504303

Zahl PH, Gøtzsche PC, Mæhlen J (2011)
Natural history of breast cancers detected in the Swedish mammography screening programme: a cohort study
Lancet Oncol, 12 (12), 1118-24
DOI 10.1016/S1470-2045(11)70250-9, PubMed 21996169

Publications 2010

Dahl TB, Haukeland JW, Yndestad A, Ranheim T, Gladhaug IP, Damås JK, Haaland T, Løberg EM, Arntsen B, Birkeland K, Bjøro K, Ulven SM, Konopski Z, Nebb HI, Aukrust P, Halvorsen B (2010)
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873

Dalen ML, Alme TN, Munkeby BH, Løberg EM, Pripp AH, Mollnes TE, Rootwelt T, Saugstad OD (2010)
Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation
J Perinat Med, 38 (5), 545-56
DOI 10.1515/JPM.2010.081, PubMed 20629493

Ellingsen CL, Maehlen J (2010)
[Better more than fewer autopsies]
Tidsskr Nor Laegeforen, 130 (11), 1121
DOI 10.4045/tidsskr.10.0469, PubMed 20531492

Server A, Josefsen R, Kulle B, Maehlen J, Schellhorn T, Gadmar Ø, Kumar T, Haakonsen M, Langberg CW, Nakstad PH (2010)
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors
Acta Radiol, 51 (3), 316-25
DOI 10.3109/02841850903482901, PubMed 20092374

Slettedal JK, Nilssen DO, Magelssen M, Løberg EM, Maehlen J (2010)
Brain pathology in fatal serotonin syndrome: presentation of two cases
Neuropathology, 31 (3), 265-70
DOI 10.1111/j.1440-1789.2010.01153.x, PubMed 20880320

Solberg R, Løberg EM, Andresen JH, Wright MS, Charrat E, Khrestchatisky M, Rivera S, Saugstad OD (2010)
Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF
PLoS One, 5 (12), e14261
DOI 10.1371/journal.pone.0014261, PubMed 21151608

Strøm BO, Aden P, Mathisen GH, Lømo J, Davanger S, Paulsen RE (2010)
Transfection of chicken cerebellar granule neurons used to study glucocorticoid receptor regulation by nuclear receptor 4A (NR4A)
J Neurosci Methods, 193 (1), 39-46
DOI 10.1016/j.jneumeth.2010.08.012, PubMed 20727911

Zahl PH, Maehlen J (2010)
[Breast cancer mortality versus breast cancer survival]
Tidsskr Nor Laegeforen, 130 (3), 261
DOI 10.4045/tidsskr.10.0033, PubMed 20160765

Publications 2009

Andresen JH, Løberg EM, Wright M, Goverud IL, Stray-Pedersen B, Saugstad OD (2009)
Nicotine affects the expression of brain-derived neurotrophic factor mRNA and protein in the hippocampus of hypoxic newborn piglets
J Perinat Med, 37 (5), 553-60
DOI 10.1515/JPM.2009.081, PubMed 19492919

Gøtzsche PC, Jørgensen KJ, Maehlen J, Zahl PH (2009)
Estimation of lead time and overdiagnosis in breast cancer screening
Br J Cancer, 100 (1), 219; author reply 220
DOI 10.1038/sj.bjc.6604762, PubMed 19127274

Haukeland JW, Konopski Z, Eggesbø HB, von Volkmann HL, Raschpichler G, Bjøro K, Haaland T, Løberg EM, Birkeland K (2009)
Metformin in patients with non-alcoholic fatty liver disease: a randomized, controlled trial
Scand J Gastroenterol, 44 (7), 853-60
DOI 10.1080/00365520902845268, PubMed 19811343

Honda M, Eriksson KS, Zhang S, Tanaka S, Lin L, Salehi A, Hesla PE, Maehlen J, Gaus SE, Yanagisawa M, Sakurai T, Taheri S, Tsuchiya K, Honda Y, Mignot E (2009)
IGFBP3 colocalizes with and regulates hypocretin (orexin)
PLoS One, 4 (1), e4254
DOI 10.1371/journal.pone.0004254, PubMed 19158946

Hugdahl K, Løberg EM, Nygård M (2009)
Left temporal lobe structural and functional abnormality underlying auditory hallucinations in schizophrenia
Front Neurosci, 3 (1), 34-45
DOI 10.3389/neuro.01.001.2009, PubMed 19753095

Liestøl K, Tretli S, Tverdal A, Maehlen J (2009)
Tuberculin status, socioeconomic differences and differences in all-cause mortality: experience from Norwegian cohorts born 1910-49
Int J Epidemiol, 38 (2), 427-34
DOI 10.1093/ije/dyn347, PubMed 19339259

Negaard A, Loberg EM, Naess PA, Eriksen M, Klow NE (2009)
Feasibility of MRI in experimentally induced inflammatory small bowel disease: a pilot study in a porcine model
Dig Dis Sci, 55 (1), 14-20
DOI 10.1007/s10620-008-0707-y, PubMed 19301126

Pedersen ED, Løberg EM, Vege E, Daha MR, Maehlen J, Mollnes TE (2009)
In situ deposition of complement in human acute brain ischaemia
Scand J Immunol, 69 (6), 555-62
DOI 10.1111/j.1365-3083.2009.02253.x, PubMed 19439017

Server A, Kulle B, Maehlen J, Josefsen R, Schellhorn T, Kumar T, Langberg CW, Nakstad PH (2009)
Quantitative apparent diffusion coefficients in the characterization of brain tumors and associated peritumoral edema
Acta Radiol, 50 (6), 682-9
DOI 10.1080/02841850902933123, PubMed 19449234

Suhrke P, Zahl PH, Maehlen J (2009)
Declining breast cancer incidence and decreased HRT use
Lancet, 373 (9662), 460-1; author reply 461
DOI 10.1016/S0140-6736(09)60166-5, PubMed 19200913

Tveito K, Hetta AK, Askedal M, Brunborg C, Sandvik L, Løberg EM, Skar V (2009)
A novel one-hour 13C-sorbitol breath test versus the H2-sorbitol breath test for assessment of coeliac disease
Scand J Gastroenterol, 44 (7), 813-9
DOI 10.1080/00365520902846233, PubMed 19333820

Yndestad A, Haukeland JW, Dahl TB, Bjøro K, Gladhaug IP, Berge C, Damås JK, Haaland T, Løberg EM, Linnestad P, Birkeland K, Konopski Z, Halvorsen B, Berge RK, Aukrust P (2009)
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130

Zahl PH, Maehlen J, Welch HG (2009)
Breast Cancer Overdiagnosis With Screening Mammography Reply
Arch. Intern. Med., 169 (10), 1000-1001
DOI 10.1001/archinternmed.2009.96

Publications 2008

Aden P, Goverud I, Liestøl K, Løberg EM, Paulsen RE, Maehlen J, Lømo J (2008)
Low-potency glucocorticoid hydrocortisone has similar neurotoxic effects as high-potency glucocorticoid dexamethasone on neurons in the immature chicken cerebellum
Brain Res, 1236, 39-48
DOI 10.1016/j.brainres.2008.07.095, PubMed 18706896

Berry DA, Baines CJ, Baum M, Dickersin K, Fletcher SW, Gøtzsche PC, Jørgensen KJ, Junod B, Maehlen J, Schwartz LM, Welch HG, Woloshin S, Thornton H, Zahl PH (2008)
Flawed inferences about screening mammography's benefit based on observational data
J Clin Oncol, 27 (4), 639-40; author reply 641-2
DOI 10.1200/JCO.2008.17.9341, PubMed 19075270

Tveito K, Brunborg C, Sandvik L, Løberg EM, Skar V (2008)
13C-xylose and 14C-xylose breath tests for the diagnosis of coeliac disease
Scand J Gastroenterol, 43 (2), 166-73
DOI 10.1080/00365520701659118, PubMed 17891683

Urdal P, Sandstad O, Løberg EM, Haug KB (2008)
[Useful genetic test for lactase deficiency]
Tidsskr Nor Laegeforen, 128 (5), 593
PubMed 18311211

Zahl PH, Jørgensen KJ, Maehlen J, Gøtzsche PC (2008)
Biases in estimates of overdetection due to mammography screening
Lancet Oncol, 9 (3), 199-201; author reply 201-2
DOI 10.1016/S1470-2045(08)70049-4, PubMed 18308246

Zahl PH, Maehlen J, Welch HG (2008)
The natural history of invasive breast cancers detected by screening mammography
Arch Intern Med, 168 (21), 2311-6
DOI 10.1001/archinte.168.21.2311, PubMed 19029493