Ramakrishna Prabhu Gopalakrishnan

  • Researcher; PhD
 

Publications 2026

Gopalakrishnan RP, Ward JM, Greiff V, Braathen R, Hu X, Bajelan L, Quý KL, Munthe L, Huszthy PC, Bogen B (2026)
Idiotype-specific CD4+ T cells chronically stimulate autoreactive B cells to develop into B lymphomas in mice
Nat Commun, 17 (1)
DOI 10.1038/s41467-026-69916-w, PubMed 41741475

Publications 2024

Gopalakrishnan RP, Østrøm MS, Skjeldal FM, Bakke O, Bogen B, Huszthy PC (2024)
B Cells With Complementary B Cell Receptors Can Kill Each Other
Eur J Immunol, 55 (1), e202350890
DOI 10.1002/eji.202350890, PubMed 39520365

Publications 2023

Westhrin M, Blazevski J, Textor A, Abdollahi P, Gopalakrishnan RP, Ngo LT, Hofgaard PO, Heinzelbecker J, Bobic S, Fossum E, Spång HCL, Braathen R, Bogen B (2023)
Id-neoantigen vaccine induces therapeutic CD8+ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769

Publications 2022

Hinke DM, Andersen TK, Gopalakrishnan RP, Skullerud LM, Werninghaus IC, Grødeland G, Fossum E, Braathen R, Bogen B (2022)
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
Cell Rep, 39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357

Publications 2019

Andersen TCB, Kristiansen PE, Huszenicza Z, Johansson MU, Gopalakrishnan RP, Kjelstrup H, Boyken S, Sundvold-Gjerstad V, Granum S, Sørli M, Backe PH, Fulton DB, Karlsson BG, Andreotti AH, Spurkland A (2019)
The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein
J Biol Chem, 294 (42), 15480-15494
DOI 10.1074/jbc.RA119.008318, PubMed 31484725

Andersen TK, Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Fauskanger M, Tveita AA, Grødeland G, Bogen B (2019)
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000

Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Haabeth OAW, Løset GÅ, Braathen R, Schenck K, Tveita AA, Munthe LA, Bogen B (2019)
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587

Publications 2015

Moussa P, Abrahamsen G, Fodil N, Gopalakrishnan RP, Mancini M, Dissen E, Sæther PC, Wiltshire SA, Boivin GA, Caignard G, Spurkland A, Vidal SM (2015)
Reduced MCMV Δm157 viral clearance in the absence of TSAd
Sci Rep, 5, 9219
DOI 10.1038/srep09219, PubMed 25783199

Publications 2014

Granum S, Sundvold-Gjerstad V, Gopalakrishnan RP, Berge T, Koll L, Abrahamsen G, Sørlie M, Spurkland A (2014)
The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192
Sci Signal, 7 (355), ra118
DOI 10.1126/scisignal.2005384, PubMed 25492967