Publications 2022

Kennedy L, Glesaaen ER, Palibrk V, Pannone M, Wang W, Al-Jabri A, Suganthan R, Meyer N, Austbø ML, Lin X, Bergersen LH, Bjørås M, Rinholm JE (2022)
Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
Elife, 11
DOI 10.7554/eLife.76451, PubMed 35942676

Publications 2021

Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, Syrstad MD, Slupphaug G, Eide L, Klungland A, Sætrom P, Luna L, Ye J, Scheffler K, Bjørås M (2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
Commun Biol, 4 (1), 1354
DOI 10.1038/s42003-021-02864-x, PubMed 34857879

Kong XY, Huse C, Yang K, Øgaard J, Berges N, Vik ES, Nawaz MS, Quiles-Jiménez A, Abbas A, Gregersen I, Holm S, Bjerkli V, Rashidi A, Fladeby C, Suganthan R, Sagen EL, Skjelland M, Lång A, Bøe SO, Bjørås M, Aukrust P, Alseth I, Halvorsen B, Dahl TB (2021)
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J Am Heart Assoc, 10 (14), e020656
DOI 10.1161/JAHA.120.020656, PubMed 34259011

Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552

Publications 2020

Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667

Połeć A, Rowe AD, Blicher P, Suganthan R, Bjørås M, Bøe SO (2020)
PML Regulates the Epidermal Differentiation Complex and Skin Morphogenesis during Mouse Embryogenesis
Genes (Basel), 11 (10)
DOI 10.3390/genes11101130, PubMed 32992884

Rodriguez-Vargas JM, Martin-Hernandez K, Wang W, Kunath N, Suganthan R, Amé JC, Oliver FJ, Ye J, Bjørås M, Dantzer F (2020)
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
Cell Death Dis, 11 (11), 954
DOI 10.1038/s41419-020-03167-5, PubMed 33159039

Scheffler K, Jalland CMO, Benestad SL, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis MA (2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Free Radic Biol Med, 152, 348-354
DOI 10.1016/j.freeradbiomed.2020.03.030, PubMed 32259578

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

Publications 2019

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

Zhang Z, Manaf A, Li Y, Perez SP, Suganthan R, Dahl JA, Bjørås M, Klungland A (2019)
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
Mol Neurobiol, 57 (2), 997-1008
DOI 10.1007/s12035-019-01777-5, PubMed 31654318

Publications 2018

Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, Perez SP, Suganthan R, He C, Bjørås M, Klungland A (2018)
Ythdf2-mediated m⁶A mRNA clearance modulates neural development in mice
Genome Biol, 19 (1), 69
DOI 10.1186/s13059-018-1436-y, PubMed 29855337

Rognlien AGW, Wollen EJ, Atneosen-Åsegg M, Suganthan R, Bjørås M, Saugstad OD (2018)
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
J Perinat Med, 47 (1), 114-124
DOI 10.1515/jpm-2018-0172, PubMed 30020889

Publications 2017

Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M (2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Sci Rep, 7 (1), 4384
DOI 10.1038/s41598-017-04472-4, PubMed 28663564

Publications 2016

Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A (2016)
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Nature, 537 (7621), 548-552
DOI 10.1038/nature19360, PubMed 27626377

Jalland CM, Scheffler K, Benestad SL, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis MA (2016)
Neil3 induced neurogenesis protects against prion disease during the clinical phase
Sci Rep, 6, 37844
DOI 10.1038/srep37844, PubMed 27886261

Palibrk V, Suganthan R, Scheffler K, Wang W, Bjørås M, Bøe SO (2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic-ischemic encephalopathy model
Cell Death Dis, 7 (7), e2320
DOI 10.1038/cddis.2016.223, PubMed 27468695

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A et al. (2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939

Publications 2015

Bjørge MD, Hildrestrand GA, Scheffler K, Suganthan R, Rolseth V, Kuśnierczyk A, Rowe AD, Vågbø CB, Vetlesen S, Eide L, Slupphaug G, Nakabeppu Y, Bredy TW, Klungland A, Bjørås M (2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
Cell Rep, 13 (12), 2671-8
DOI 10.1016/j.celrep.2015.12.001, PubMed 26711335

Publications 2014

Bliksøen M, Baysa A, Eide L, Bjørås M, Suganthan R, Vaage J, Stensløkken KO, Valen G (2014)
Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart
J Mol Cell Cardiol, 78, 9-22
DOI 10.1016/j.yjmcc.2014.11.010, PubMed 25446179

Booth JA, Suganthan R, Gaustad P, Bjørås M (2014)
Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic
Int J Antimicrob Agents, 45 (2), 196-7
DOI 10.1016/j.ijantimicag.2014.10.005, PubMed 25465525

Publications 2013

Jalland CM, Benestad SL, Ersdal C, Scheffler K, Suganthan R, Nakabeppu Y, Eide L, Bjørås M, Tranulis MA (2013)
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage
Free Radic Biol Med, 68, 1-7
DOI 10.1016/j.freeradbiomed.2013.11.013, PubMed 24296244

Rolseth V, Krokeide SZ, Kunke D, Neurauter CG, Suganthan R, Sejersted Y, Hildrestrand GA, Bjørås M, Luna L (2013)
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress
Biochim Biophys Acta, 1833 (5), 1157-64
DOI 10.1016/j.bbamcr.2012.12.024, PubMed 23305905

Publications 2012

Regnell CE, Hildrestrand GA, Sejersted Y, Medin T, Moldestad O, Rolseth V, Krokeide SZ, Suganthan R, Luna L, Bjørås M, Bergersen LH (2012)
Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells
Cell Rep, 2 (3), 503-10
DOI 10.1016/j.celrep.2012.08.008, PubMed 22959434

Publications 2011

Halsne R, Esbensen Y, Wang W, Scheffler K, Suganthan R, Bjørås M, Eide L (2011)
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis
DNA Repair (Amst), 11 (3), 278-85
DOI 10.1016/j.dnarep.2011.12.001, PubMed 22209780

Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M (2011)
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
DOI 10.1073/pnas.1106880108, PubMed 22065741

Wang W, Esbensen Y, Kunke D, Suganthan R, Rachek L, Bjørås M, Eide L (2011)
Mitochondrial DNA damage level determines neural stem cell differentiation fate
J Neurosci, 31 (26), 9746-51
DOI 10.1523/JNEUROSCI.0852-11.2011, PubMed 21715639