TTA - Turning the Tide of Antimicrobial resistance

Antimicrobial resistance (AMR) is emerging as a local and global threat to health care practice.

The main goal of the TTA network is to combat AMR by securing optimal diagnostics and drugs in order to address clinical signs and symptoms, transmission, treatment and optimized contact tracing. Our molecular profiling capacity provides unique methodologies to identify the genes that contribute to the AMR phenotype, defining the strong potential to generate core knowledge in pathogenesis and identify new diagnostics, vaccines and drug targets.

To insure the translation of this work into global health policy, we will examine the normative guidance, stakeholder involvement, and policy interventions needed to make novel diagnostics and novel antimicrobial therapy globally accessible, particularly in low- and middle-income countries.

TTA will embark on AMR as a complex and ethical challenge in global health. The consortium, with experts from both clinical medicine, natural sciences, humanities and social sciences, offers a unique opportunity for addressing AMR in a comprehensive manner.

The TTA consortium is formed by strong research groups in OUS divisions with complementary expertise teamed up with national and international collaborators.


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National Consortium for Microbial Genomics on December 7th 2017


The Norwegian Consortium for Microbial Genomics (NCMG) was established in 2016 to stimulate the development of Next Generation Sequencing (NGS) for microbiology in a One Health perspective in Norway.

 The aim of the consortium is to provide a platform: 

  • to establish culture-independent diagnostics for infectious diseases based on NGS
  • to implement NGS as an epidemiological tool in Norway in order to detect virulence and antibiotic resistance changes in human and zoonotic pathogens
  • to develop health registries of NGS data to support public health decisions
  • to establish a network for bioinformaticians to deal with NGS data for microbiology and to support research using NGS within the field of microbiology

The first meeting of the consortium in May 2016 assembled about 70 participants and the programme included invited speakers from the UK and Sweden in addition to national experts. We hope to renew last year’s success and hereby invite you to this one-day seminar on December 7 at Folkehelseinstituttet. 

More information here



NewsSuccessful ABS/TTA workshop Nov. 23 2017

Research and innovation opportunities in Antimicrobial stewardship programs

Celine Pulcini (Université de Lorraine)
Jenny Dahl-Knudsen (Hvidovre, DK)
Dag Berild (OUS)
Jon Birger Haug (SØF)
Silje Jørgensen (Ahus)
Lars Småbrekke (UNN)
Jannicke Slettli Watne (KAS)
Arne Søraas (OUS)
Full program

The day was initiated by inspiring talks to facilitate a good discussion in the workshop session. The participants were to define specific recommendations for improving antibiotic stewardship at OUS. By identifying the gap/need, benefit/effect and solution and selecting one/two recommendations, they eagerly presented who, how and why this was to be prioritized. The input will be presented in a report that will be handed to the project owner of the OUS antimicrobial stewardship program at OUS.

Picture film




In the mediaTTA member Pål Rongved presenting his research in TU


NewsTTA at Oslo Innovation Week & the Norwegian Cancer Society "Antibiotic resistance and cancer" 27 Sep. 2017

TTA members Tone Tønjum and Dag Berild presented at the Norwegian Cancer Society's (Kreftforeningen) seminar on Antibiotic resistance and cancer - Current status, and how to prevent a potential apocalyptic scenario #OIW2017 at the new "Vitensenter" in Kongens gate 6.

Live stream:


NewsTTA at Oslo Science Expo (Forskningstorget)

TTA was present with a stand at "Forskningstorget" in Oslo Sep. 22-23.

Oslo Science Expo (Forskningstorget) is part of the National Science Week in Norway (Forskningsdagene), a nationwide event held every year to make science and research available to the public.

This years theme was "values" and TTA emphasized the importance of reducing the use of antibiotic and good hygiene to combat the development of antimicrobial resistance.



TTA contributes to "Ekspertsykehusets blogg"

Members of TTA have contributed with several articles for OUS «Ekspertsykehusets blogg» in a series

dedicated to antimicrobial resistance this April and May 2017. The contributions are linked below.

Vi står overfor den største utfordringen på det medisinske feltet i vår tid!1. JuniFredrik Müller
Resistent tuberkulose på vei inn i landet31. MaiTone Tønjum
Hjartebarna og dei resistente bakteriane 30. MaiHeine Århus
Unngå unødvendig antibiotika til ”minsten”24. MaiPer Kristian Knudsen
Bakterier stoppes ikke i passkontrollen22. MaiSilje Bakken Jørgensen og Anita Blomfeldt
5 alternativer til antibiotika19. MaiTone Tønjum, Jessica Lönnn-Stensrud, Ute Krengel og Julie E. Heggelund
Et KUPP til fastlegene i Oslo15. MaiAleksander Wesnes
9 råd til russen10. MaiTone Tønjum
Gonoré: Sex og lure bakterier5. MaiTone Tønjum, Miriam Sare Ledaal, Linn Merete Brendefur Corwin, Anne O. Olsen, Patricia Merckoll, Fredrik Müller
Riktig dose til riktig pasient – måling av antibiotikanivå i blod2. MaiKari Kjeldstadli
En varslet katastrofe28. AprilAnne Helene Kveim Lie
Brilliante bakterier24. AprilJessica Lönn-Stensrud
Kan man bli smittet av antibiotikaresistente bakterier når man bader?21. AprilSilje Bakken Jørgensen
Leger uten våpen18. AprilDag Berild

TTA allmøte 15.06.17 kl 12 DM4

The various projects will be presented by the WP leaders: Tone Tønjum, Dag Berild, Jørgen Vildershøy Bjørnholt and Pål Rongved from TTA, as well as Truls Leegaard (AHUS) and Dagfinn Skaare (SiV) from the HSØ Regional Network for AMR.

Wraps will be served from 12.00 and the meeting begins at. 12.30 and lasts until 13.45.

Register at:
The deadline for registration is Tuesday 13.06 10 pm.

Location: Gaustad in the Domus Medica Extension (DM4) seminar room LU-035 (plan 0).


TTA goes Nordic 2 April 27-28 2017

 April 27-28 2017 at The Rotunda and Mezzanine at the University of Oslo, Gaustad

"Turning the tide of antimicrobial resistance - the 2nd  Nordic TTA Conference".

The main goal for this meeting is to highlight news on AMR and promote Nordic interactions and collaboration on AMR-related topics.

 Register for the conference here 

Download program (PDF-format)

 Nordic meeting November 28 at The Norwegian Academy for Science and Letters  
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