Publications

Publications 2022

Ali O, Farooq A, Yang M, Jin VX, Bjørås M, Wang J (2022)
abc4pwm: affinity based clustering for position weight matrices in applications of DNA sequence analysis
BMC Bioinformatics, 23 (1), 83
DOI 10.1186/s12859-022-04615-z, PubMed 35240993

Anda EE, Braaten T, Borch KB, Nøst TH, Chen SLF, Lukic M, Lund E, Forland F, Leon DA, Winje BA, Kran AB, Kalager M, Johansen FL, Sandanger TM (2022)
Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21
Euro Surveill, 27 (13)
DOI 10.2807/1560-7917.ES.2022.27.13.2100376, PubMed 35362405

Andersen T, Ueland T, Aukrust P, Nilsen DW, Grundt H, Staines H, Kontny F (2022)
Podocan and Adverse Clinical Outcome in Patients Admitted With Suspected Acute Coronary Syndromes
Front Cardiovasc Med, 9, 867944
DOI 10.3389/fcvm.2022.867944, PubMed 35669474

Asaduzzaman M, Rodland EK, Mekonnen Z, Gradmann C, Winkler AS (2022)
Understanding transmission pathways and integrated digital surveillance potential of antimicrobial resistance in Ethiopia in a One Health approach: a mixed-method study protocol
BMJ Open, 12 (6), e051022
DOI 10.1136/bmjopen-2021-051022, PubMed 35680276

Aukrust CG, Parikh K, Smart LR, Mdala I, Fjeld HE, Lubuulwa J, Makene AM, Härtl R, Winkler AS (2022)
Pediatric Hydrocephalus in Northwest Tanzania: A Descriptive Cross-Sectional Study of Clinical Characteristics and Early Surgical Outcomes from the Bugando Medical Centre
World Neurosurg, 161, e339-e346
DOI 10.1016/j.wneu.2022.02.003, PubMed 35134579

Aune SK, Bonnevie-Svendsen M, Nyborg C, Trøseid M, Seljeflot I, Hisdal J, Helseth R (2022)
Gut Leakage and Cardiac Biomarkers after Prolonged Strenuous Exercise
Med Sci Sports Exerc, 54 (9), 1476-1482
DOI 10.1249/MSS.0000000000002948, PubMed 35482788

Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, Zhou H, Bajaj JS, Hylemon PB, Ting J, Popov YV, Hov JR, Francis HL, Sartor RB (2022)
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
Gut (in press)
DOI 10.1136/gutjnl-2021-326500, PubMed 35705368

Bady P, Marosi C, Weller M, Grønberg BH, Schultz H, Taphoorn MJB, Gijtenbeek JMM, van den Bent MJ, von Deimling A, Stupp R, Malmström A, Hegi ME (2022)
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients
Acta Neuropathol Commun, 10 (1), 39
DOI 10.1186/s40478-022-01344-5, PubMed 35331339

Begley C, Wagner RG, Abraham A, Beghi E, Newton C, Kwon CS, Labiner D, Winkler AS (2022)
The global cost of epilepsy: A systematic review and extrapolation
Epilepsia, 63 (4), 892-903
DOI 10.1111/epi.17165, PubMed 35195894

Berg J, Halvorsen AR, Bengtson MB, Lindberg M, Halvorsen B, Aukrust P, Helland Å, Ueland T (2022)
Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
Front Immunol, 13, 875152
DOI 10.3389/fimmu.2022.875152, PubMed 35911763

Birhanu AG, Gómez-Muñoz M, Kalayou S, Riaz T, Lutter T, Yimer SA, Abebe M, Tønjum T (2022)
Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress
ACS Omega, 7 (4), 3470-3482
DOI 10.1021/acsomega.1c05923, PubMed 35128256

Brautaset Englund KV, Østby CM, Broch K, Ueland T, Aukrust P, Gude E, Andreassen AK, Gullestad L (2022)
Iron homeostasis in heart transplant recipients randomized to ferric derisomaltose or placebo
Clin Transplant, 36 (7), e14695
DOI 10.1111/ctr.14695, PubMed 35532871

Bril'kov MS, Dobrovolska O, Ødegård-Fougner Ø, Turcu DC, Strømland Ø, Underhaug J, Aasland R, Halskau Ø (2022)
Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix
Front Mol Biosci, 9, 763750
DOI 10.3389/fmolb.2022.763750, PubMed 35495628

Braadland PR, Schneider KM, Bergquist A, Molinaro A, Lövgren-Sandblom A, Henricsson M, Karlsen TH, Vesterhus M, Trautwein C, Hov JR, Marschall HU (2022)
Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis
JHEP Rep, 4 (11), 100561
DOI 10.1016/j.jhepr.2022.100561, PubMed 36176935

Bublitz SK, Mie E, Wasner M, Hapfelmeier A, Geiseler J, Lorenzl S, Winkler AS (2022)
Thick Mucus in ALS: A Mixed-Method Study on Associated Factors and Its Impact on Quality of Life of Patients and Caregivers
Brain Sci, 12 (2)
DOI 10.3390/brainsci12020252, PubMed 35204016

Busek M, Aizenshtadt A, Amirola-Martinez M, Delon L, Krauss S (2022)
Academic User View: Organ-on-a-Chip Technology
Biosensors (Basel), 12 (2)
DOI 10.3390/bios12020126, PubMed 35200386

Bøås H, Bekkevold T, Havdal LB, Kran AB, Rojahn AE, Størdal K, Debes S, Døllner H, Nordbø SA, Barstad B, Haarr E, Vázquez Fernández L, Nakstad B, Leegaard TM, Hungnes O, Flem E, Norwegian Enhanced Pediatric Immunisation Surveillance (NorEPIS) Network (2022)
The burden of hospital-attended influenza in Norwegian children
Front Pediatr, 10, 963274
DOI 10.3389/fped.2022.963274, PubMed 36160779

Castelpietra G, Knudsen AKS, Agardh EE, Armocida B, Beghi M, Iburg KM, Logroscino G, Ma R, Starace F, Steel N, Addolorato G, Andrei CL, Andrei T, Ayuso-Mateos JL, Banach M, Bärnighausen TW, Barone-Adesi F, Bhagavathula AS, Carvalho F, Carvalho M, Chandan JS, Chattu VK, Couto RAS, Cruz-Martins N, Dargan PI et al. (2022)
The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019
Lancet Reg Health Eur, 16, 100341
DOI 10.1016/j.lanepe.2022.100341, PubMed 35392452

Chewapreecha C, Pensar J, Chattagul S, Pesonen M, Sangphukieo A, Boonklang P, Potisap C, Koosakulnirand S, Feil EJ, Dunachie S, Chantratita N, Limmathurotsakul D, Peacock SJ, Day NPJ, Parkhill J, Thomson NR, Sermswan RW, Corander J (2022)
Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment
Mol Biol Evol, 39 (1)
DOI 10.1093/molbev/msab306, PubMed 34662416

Christensen EE, Binde C, Leegaard M, Tonby K, Dyrhol-Riise AM, Kvale D, Amundsen EK, Holten AR (2022)
Diagnostic accuracy and added value of infection biomarkers in patients with possible sepsis in the Emergency Department
Shock (in press)
DOI 10.1097/SHK.0000000000001981, PubMed 36130401

Christensen I, Berild D, Jelsness-Jørgensen LP, Bjørnholt JV, Haug JB (2022)
Tailored interventions result in better antimicrobial management in Norwegian hospitals
Tidsskr Nor Laegeforen, 142 (5)
DOI 10.4045/tidsskr.22.0094, PubMed 35324115

Christensen I, Haug JB, Berild D, Bjørnholt JV, Skodvin B, Jelsness-Jørgensen LP (2022)
Factors Affecting Antibiotic Prescription among Hospital Physicians in a Low-Antimicrobial-Resistance Country: A Qualitative Study
Antibiotics (Basel), 11 (1)
DOI 10.3390/antibiotics11010098, PubMed 35052975

Chung BK, Øgaard J, Reims HM, Karlsen TH, Melum E (2022)
Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
Hepatol Commun, 6 (9), 2538-2550
DOI 10.1002/hep4.2001, PubMed 35726350

Clarsen B, Nylenna M, Klitkou ST, Vollset SE, Baravelli CM, Bølling AK, Aasvang GM, Sulo G, Naghavi M, Pasovic M, Asaduzzaman M, Bjørge T, Eggen AE, Eikemo TA, Ellingsen CL, Haaland ØA, Hailu A, Hassan S, Hay SI, Juliusson PB, Kisa A, Kisa S, Månsson J, Mekonnen T, Murray CJL et al. (2022)
Changes in life expectancy and disease burden in Norway, 1990-2019: an analysis of the Global Burden of Disease Study 2019
Lancet Public Health, 7 (7), e593-e605
DOI 10.1016/S2468-2667(22)00092-5, PubMed 35779543

Coggan KA, Higgs MG, Brutinel ED, Marden JN, Intile PJ, Winther-Larsen HC, Koomey M, Yahr TL, Wolfgang MC (2022)
Global Regulatory Pathways Converge To Control Expression of Pseudomonas aeruginosa Type IV Pili
mBio, e0369621 (in press)
DOI 10.1128/mbio.03696-21, PubMed 35073734

Corander J, Hanage WP, Pensar J (2022)
Causal discovery for the microbiome
Lancet Microbe (in press)
DOI 10.1016/S2666-5247(22)00186-0, PubMed 36152674

Crivelli L, Palmer K, Calandri I, Guekht A, Beghi E, Carroll W, Frontera J, García-Azorín D, Westenberg E, Winkler AS, Mangialasche F, Allegri RF, Kivipelto M (2022)
Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis
Alzheimers Dement, 18 (5), 1047-1066
DOI 10.1002/alz.12644, PubMed 35297561

Cruz R, Almeida SD, Heredia ML, Quintela I, Ceballos FC, Pita G, Lorenzo-Salazar JM, González-Montelongo R, Gago-Domínguez M, Porras MS, Castaño JAT, Nevado J, Aguado JM, Aguilar C, Aguilera-Albesa S, Almadana V, Almoguera B, Alvarez N, Andreu-Bernabeu Á, Arana-Arri E, Arango C, Arranz MJ, Artiga MJ, Baptista-Rosas RC, Barreda-Sánchez M et al. (2022)
Novel genes and sex differences in COVID-19 severity
Hum Mol Genet (in press)
DOI 10.1093/hmg/ddac132, PubMed 35708486

Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Ortiz AB, Salazar A, Chercoles AG, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A et al. (2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet (in press)
DOI 10.1093/hmg/ddac158, PubMed 35848942

Demleitner AF, Wolff AW, Erber J, Gebhardt F, Westenberg E, Winkler AS, Kolbe-Busch S, Chaberny IF, Lingor P (2022)
Best practice approaches to outpatient management of people living with Parkinson's disease during the COVID-19 pandemic
J Neural Transm (Vienna) (in press)
DOI 10.1007/s00702-022-02484-7, PubMed 35244753

Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169

Enserink JM (2022)
The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
Bioessays, 44 (7), e2200065
DOI 10.1002/bies.202200065, PubMed 35655365

Enserink JM, Chymkowitch P (2022)
Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
Int J Mol Sci, 23 (3)
DOI 10.3390/ijms23031293, PubMed 35163213

Fraz MSA, Michelsen AE, Moe N, Aaløkken TM, Macpherson ME, Nordøy I, Aukrust P, Taraldsrud E, Holm AM, Ueland T, Jørgensen SF, Fevang B (2022)
Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency
J Clin Immunol (in press)
DOI 10.1007/s10875-022-01318-1, PubMed 35789314

Frischmuth T, Hindberg K, Aukrust P, Ueland T, Braekkan SK, Hansen JB, Morelli VM (2022)
Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
J Thromb Haemost, 20 (7), 1618-1626
DOI 10.1111/jth.15701, PubMed 35289062

Frontera JA, Tamborska AA, Doheim MF, Garcia-Azorin D, Gezegen H, Guekht A, Yusof Khan AHK, Santacatterina M, Sejvar J, Thakur KT, Westenberg E, Winkler AS, Beghi E, contributors from the Global COVID-19 Neuro Research Coalition (2022)
Neurological Events Reported after COVID-19 Vaccines: An Analysis of VAERS
Ann Neurol (in press)
DOI 10.1002/ana.26339, PubMed 35233819

Garcia-Azorin D, Baykan B, Beghi E, Doheim MF, Fernandez-de-Las-Penas C, Gezegen H, Guekht A, Hoo FK, Santacatterina M, Sejvar J, Tamborska AA, Thakur KT, Westenberg E, Winkler AS, Frontera JA, Contributors from the Global COVID-19 Neuro Research Coalition (2022)
Timing of headache after COVID-19 vaccines and its association with cerebrovascular events: An analysis of 41,700 VAERS reports
Cephalalgia, 42 (11-12), 1207-1217
DOI 10.1177/03331024221099231, PubMed 35514199

Gelpi M, Vestad B, Raju SC, Hansen SH, Høgh J, Midttun Ø, Ueland PM, Ueland T, Benfield T, Kofoed KF, Hov JR, Trøseid M, Nielsen SD (2022)
Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
J Infect Dis, 225 (11), 1948-1954
DOI 10.1093/infdis/jiac018, PubMed 35089326

Global Burden of Disease 2019 Cancer Collaboration, Kocarnik JM, Compton K, Dean FE, Fu W, Gaw BL, Harvey JD, Henrikson HJ, Lu D, Pennini A, Xu R, Ababneh E, Abbasi-Kangevari M, Abbastabar H, Abd-Elsalam SM, Abdoli A, Abedi A, Abidi H, Abolhassani H, Adedeji IA, Adnani QES, Advani SM, Afzal MS, Aghaali M, Ahinkorah BO et al. (2022)
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019
JAMA Oncol, 8 (3), 420-444
DOI 10.1001/jamaoncol.2021.6987, PubMed 34967848

Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M et al. (2022)
LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
BMC Public Health, 22 (1), 1385
DOI 10.1186/s12889-022-13724-6, PubMed 35854275

Hadjineophytou C, Anonsen JH, Svingerud T, Mortimer TD, Grad YH, Scott NE, Koomey M (2022)
Sculpting the Bacterial O-Glycoproteome: Functional Analyses of Orthologous Oligosaccharyltransferases with Diverse Targeting Specificities
mBio, 13 (3), e0379721
DOI 10.1128/mbio.03797-21, PubMed 35471082

Havdal LB, Bøås H, Bekkevold T, Bakken Kran AM, Rojahn AE, Størdal K, Debes S, Døllner H, Nordbø SA, Barstad B, Haarr E, Fernández LV, Nakstad B, Inchley C, Flem E (2022)
Risk factors associated with severe disease in respiratory syncytial virus infected children under 5 years of age
Front Pediatr, 10, 1004739
DOI 10.3389/fped.2022.1004739, PubMed 36110112

Heldal TF, Åsberg A, Ueland T, Reisaeter AV, Pischke SE, Mollnes TE, Aukrust P, Hartmann A, Heldal K, Jenssen T (2022)
Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
Am J Transplant, 22 (8), 2016-2027
DOI 10.1111/ajt.17047, PubMed 35352462

Hole MJ, Kaasen Jørgensen K, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2022)
A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
Hepatology (in press)
DOI 10.1002/hep.32773, PubMed 36056902

Holst C, Stelzle D, Diep LM, Sukums F, Ngowi B, Noll J, Winkler AS (2022)
Improving Health Knowledge Through Provision of Free Digital Health Education to Rural Communities in Iringa, Tanzania: Nonrandomized Intervention Study
J Med Internet Res, 24 (7), e37666
DOI 10.2196/37666, PubMed 35900820

Huse C, Anstensrud AK, Michelsen AE, Ueland T, Broch K, Woxholt S, Yang K, Sharma K, Tøllefsen IM, Bendz B, Amundsen BH, Damås JK, Berg ES, Bjørkelund E, Quiles-Jiménez A, Bjerkeli V, Bendz C, Kleveland O, Stensaeth KH, Opdahl A, Kløw NE, Andersen GØ, Wiseth R, Halvorsen B, Gullestad L et al. (2022)
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178

Ianevski A, Simonsen RM, Myhre V, Tenson T, Oksenych V, Bjørås M, Kainov DE (2022)
DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac348, PubMed 35610052

Ianevski A, Yao R, Simonsen RM, Myhre V, Ravlo E, Kaynova GD, Zusinaite E, White JM, Polyak SJ, Oksenych V, Windisch MP, Pan Q, Lastauskienė E, Vitkauskienė A, Matukevičius A, Tenson T, Bjørås M, Kainov DE (2022)
Mono- and combinational drug therapies for global viral pandemic preparedness
iScience, 25 (4), 104112
DOI 10.1016/j.isci.2022.104112, PubMed 35402870

Ianevski A, Zusinaite E, Tenson T, Oksenych V, Wang W, Afset JE, Bjørås M, Kainov DE (2022)
Novel Synergistic Anti-Enteroviral Drug Combinations
Viruses, 14 (9)
DOI 10.3390/v14091866, PubMed 36146673

Karlsen TH (2022)
Understanding COVID-19 through genome-wide association studies
Nat Genet, 54 (4), 368-369
DOI 10.1038/s41588-021-00985-x, PubMed 35410380

Karlsen TR, Olsen MB, Kong XY, Yang K, Quiles-Jiménez A, Kroustallaki P, Holm S, Lines GT, Aukrust P, Skarpengland T, Bjørås M, Dahl TB, Nilsen H, Gregersen I, Halvorsen B (2022)
NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length
Biochem Biophys Rep, 29, 101211
DOI 10.1016/j.bbrep.2022.101211, PubMed 35079641

Keleş Atıcı R, Doğan ŞD, Gündüz MG, Krishna VS, Chebaiki M, Homberset H, Lherbet C, Mourey L, Tønjum T (2022)
Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities
Drug Dev Res, 83 (6), 1292-1304
DOI 10.1002/ddr.21958, PubMed 35769019

Keller L, Stelzle D, Schmidt V, Carabin H, Reinhold AK, Keller C, Welte TM, Richter V, Amos A, Boeckman L, Harrison W, Winkler AS (2022)
Community-level prevalence of epilepsy and of neurocysticercosis among people with epilepsy in the Balaka district of Malawi: A cross-sectional study
PLoS Negl Trop Dis, 16 (9), e0010675
DOI 10.1371/journal.pntd.0010675, PubMed 36108075

Kennedy L, Glesaaen ER, Palibrk V, Pannone M, Wang W, Al-Jabri A, Suganthan R, Meyer N, Austbø ML, Lin X, Bergersen LH, Bjørås M, Rinholm JE (2022)
Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
Elife, 11
DOI 10.7554/eLife.76451, PubMed 35942676

Knudsen AD, Bouazzi R, Afzal S, Gelpi M, Benfield T, Høgh J, Thomsen MT, Trøseid M, Nordestgaard BG, Nielsen SD (2022)
Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls
BMC Infect Dis, 22 (1), 451
DOI 10.1186/s12879-022-07450-y, PubMed 35546661

Krag A, Karlsen TH (2022)
Er leversygdomme et overset problem i Europa?
Ugeskr Laeger, 184 (8)
PubMed 35244013

Langa I, Padama F, Nhancupe N, Pondja A, Hlashwayo D, Gouveia L, Stelzle D, da Costa CP, Schmidt V, Winkler AS, Noormahomed EV (2022)
The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique
PLoS Negl Trop Dis, 16 (7), e0010606
DOI 10.1371/journal.pntd.0010606, PubMed 35834558

Lawrence G, Midtervoll I, Samuelsen SO, Kristoffersen AK, Enersen M, Håheim LL (2022)
The blood microbiome and its association to cardiovascular disease mortality: case-cohort study
BMC Cardiovasc Disord, 22 (1), 344
DOI 10.1186/s12872-022-02791-7, PubMed 35909117

Lee-Ødegård S, Ueland T, Thorsby PM, Aukrust P, Michelsen AE, Halvorsen B, Drevon CA, Birkeland KI (2022)
Fetuin-A mediates the difference in adipose tissue insulin resistance between young adult pakistani and norwegian patients with type 2 diabetes
BMC Endocr Disord, 22 (1), 208
DOI 10.1186/s12902-022-01127-y, PubMed 35978354

Lees JA, Tonkin-Hill G, Yang Z, Corander J (2022)
Mandrake: visualizing microbial population structure by embedding millions of genomes into a low-dimensional representation
Philos Trans R Soc Lond B Biol Sci, 377 (1861), 20210237
DOI 10.1098/rstb.2021.0237, PubMed 35989601

Lei L, Bruneau A, El Mourabit H, Guégan J, Folseraas T, Lemoinne S, Karlsen TH, Hoareau B, Morichon R, Gonzalez-Sanchez E, Goumard C, Ratziu V, Charbord P, Gautheron J, Tacke F, Jaffredo T, Cadoret A, Housset C (2022)
Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
Hepatology (in press)
DOI 10.1002/hep.32456, PubMed 35278227

Lekva T, Ueland T, Halvorsen B, Murphy SL, Dyrhol-Riise AM, Tveita A, Finbråten AK, Mathiessen A, Müller KE, Aaløkken TM, Skjønsberg OH, Lerum TV, Aukrust P, Dahl TB (2022)
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
Infect Dis (Lond), 1-6 (in press)
DOI 10.1080/23744235.2022.2113135, PubMed 35984738

Mallawaarachchi S, Tonkin-Hill G, Croucher NJ, Turner P, Speed D, Corander J, Balding D (2022)
Genome-wide association, prediction and heritability in bacteria with application to Streptococcus pneumoniae
NAR Genom Bioinform, 4 (1), lqac011
DOI 10.1093/nargab/lqac011, PubMed 35211669

Mazumder R, Lagoro DK, Nariai H, Danieli A, Eliashiv D, Engel J, Dalla Bernardina B, Kegele J, Lerche H, Sejvar J, Matuja W, Schmutzhard E, Bonanni P, De Polo G, Wagner T, Winkler AS (2022)
Ictal Electroencephalographic Characteristics of Nodding Syndrome: A Comparative Case-Series from South Sudan, Tanzania, and Uganda
Ann Neurol, 92 (1), 75-80
DOI 10.1002/ana.26377, PubMed 35438201

Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130

Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437

Michael BD, Walton D, Westenberg E, García-Azorín D, Singh B, Tamborska AA, Netravathi M, Chomba M, Wood GK, Easton A, Siddiqi OK, Jackson TA, Pollak TA, Nicholson TR, Nair S, Breen G, Prasad K, Thakur KT, Chou SH, Schmutzhard E, Frontera JA, Helbok R, Padovani A, Menon DK, Solomon T et al. (2022)
Consensus Clinical Guidance for Diagnosis and Management of Adult COVID-19 Encephalopathy Patients
J Neuropsychiatry Clin Neurosci, appineuropsych22010002 (in press)
DOI 10.1176/appi.neuropsych.22010002, PubMed 35872617

Mlowe F, Karimuribo E, Mkupasi E, Churi A, Nyerere AD, Schmidt V, Ngowi H, Winkler AS, Mlangwa J (2022)
Challenges in the Diagnosis of Taenia solium Cysticercosis and Taeniosis in Medical and Veterinary Settings in Selected Regions of Tanzania: A Cross-Sectional Study
Vet Med Int, 2022, 7472051
DOI 10.1155/2022/7472051, PubMed 35815231

Muhoozi GKM, Li K, Atukunda P, Skaare AB, Willumsen T, Enersen M, Westerberg AC, Morris A, Vieira AR, Iversen PO, Methé BA (2022)
Child saliva microbiota and caries: a randomized controlled maternal education trial in rural Uganda
Sci Rep, 12 (1), 7857
DOI 10.1038/s41598-022-11979-y, PubMed 35552492

Murphy SL, Halvorsen B, Barratt-Due A, Dyrhol-Riise AM, Aukrust P, Trøseid M, Dahl TB (2022)
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect (in press)
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611

Natterson-Horowitz B, Desmarchelier M, Winkler AS, Carabin H (2022)
Beyond Zoonoses in One Health: Non-communicable Diseases Across the Animal Kingdom
Front Public Health, 9, 807186
DOI 10.3389/fpubh.2021.807186, PubMed 35178374

Nissen-Meyer LSH, Hervig T, Fevang B, Norheim G, Kran AB, Vaage JT, Flesland Ø (2022)
COVID-19 convalescent plasma from Norwegian blood donors
Tidsskr Nor Laegeforen, 142 (9)
DOI 10.4045/tidsskr.22.0057, PubMed 35699539

Nyangi C, Stelzle D, Mkupasi EM, Ngowi HA, Churi AJ, Schmidt V, Mahonge C, Winkler AS (2022)
Knowledge, attitudes and practices related to Taenia solium cysticercosis and taeniasis in Tanzania
BMC Infect Dis, 22 (1), 534
DOI 10.1186/s12879-022-07408-0, PubMed 35692033

Olsen MB, Sannes AC, Yang K, Nielsen MB, Einarsen SV, Christensen JO, Pallesen S, Bjørås M, Gjerstad J (2022)
Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions
iScience, 25 (9), 104953
DOI 10.1016/j.isci.2022.104953, PubMed 36060062

Onken A, Haanshuus CG, Miraji MK, Marijani M, Kibwana KO, Abeid KA, Mørch K, Reimers M, Langeland N, Müller F, Jenum PA, Blomberg B (2022)
Malaria prevalence and performance of diagnostic tests among patients hospitalized with acute undifferentiated fever in Zanzibar
Malar J, 21 (1), 54
DOI 10.1186/s12936-022-04067-z, PubMed 35183188

Oppen K, Ueland T, Michelsen AE, Aukrust P, Steinsvik T, Skadberg Ø, Brede C, Siljan WW, Husebye E, Holter JC, Heggelund L (2022)
Hepcidin predicts 5-year mortality after community-acquired pneumonia
Infect Dis (Lond), 54 (6), 403-409
DOI 10.1080/23744235.2021.2022194, PubMed 35057702

Pereira AP, Antunes P, Willems R, Corander J, Coque TM, Peixe L, Freitas AR, Novais C (2022)
Evolution of Chlorhexidine Susceptibility and of the EfrEF Operon among Enterococcus faecalis from Diverse Environments, Clones, and Time Spans
Microbiol Spectr, 10 (4), e0117622
DOI 10.1128/spectrum.01176-22, PubMed 35862993

Prodjinotho UF, Gres V, Henkel F, Lacorcia M, Dandl R, Haslbeck M, Schmidt V, Winkler AS, Sikasunge C, Jakobsson PJ, Henneke P, Esser-von Bieren J, Prazeres da Costa C (2022)
Helminthic dehydrogenase drives PGE₂ and IL-10 production in monocytes to potentiate Treg induction
EMBO Rep, 23 (5), e54096
DOI 10.15252/embr.202154096, PubMed 35357743

Quiles-Jiménez A, Dahl TB, Bjørås M, Alseth I, Halvorsen B, Gregersen I (2022)
Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies
Stroke, 53 (6), 2114-2122
DOI 10.1161/STROKEAHA.121.037581, PubMed 35240858

Ramos-Alonso L, Garcia I, Enserink JM, Chymkowitch P (2022)
Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
STAR Protoc, 3 (1), 101210
DOI 10.1016/j.xpro.2022.101210, PubMed 35265859

Seidel S, Cruz-Bournazou MN, Groß S, Schollmeyer JK, Kurreck A, Krauss S, Neubauer P (2022)
A Comprehensive IT Infrastructure for an Enzymatic Product Development in a Digitalized Biotechnological Laboratory
Adv Biochem Eng Biotechnol, 182, 61-82
DOI 10.1007/10_2022_207, PubMed 35861884

Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530

Simeone P, Tripaldi R, Michelsen A, Ueland T, Liani R, Ciotti S, Birkeland KI, Gulseth HL, Di Castelnuovo A, Cipollone F, Aukrust P, Consoli A, Halvorsen B, Santilli F (2022)
Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss
Cardiovasc Diabetol, 21 (1), 36
DOI 10.1186/s12933-022-01469-w, PubMed 35277168

Simonsen HE, Berkman R, Skorpen PK, Hallstensen RF, Aukrust P (2022)
A man in his fifties with recurrent urticaria, fever and joint pain
Tidsskr Nor Laegeforen, 142 (4)
DOI 10.4045/tidsskr.21.0028, PubMed 35239264

Singh B, Lant S, Cividini S, Cattrall JWS, Goodwin LC, Benjamin L, Michael BD, Khawaja A, Matos AMB, Alkeridy W, Pilotto A, Lahiri D, Rawlinson R, Mhlanga S, Lopez EC, Sargent BF, Somasundaran A, Tamborska A, Webb G, Younas K, Al Sami Y, Babu H, Banks T, Cavallieri F, Cohen M et al. (2022)
Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis
PLoS One, 17 (6), e0263595
DOI 10.1371/journal.pone.0263595, PubMed 35653330

Sitali MC, Schmidt V, Mwenda R, Sikasunge CS, Mwape KE, Simuunza MC, da Costa CP, Winkler AS, Phiri IK (2022)
Experimental animal models and their use in understanding cysticercosis: A systematic review
PLoS One, 17 (7), e0271232
DOI 10.1371/journal.pone.0271232, PubMed 35853079

Stelzle D, Kaducu J, Schmidt V, Welte TM, Ngowi BJ, Matuja W, Escheu G, Hauke P, Richter V, Ovuga E, Pfausler B, Schmutzhard E, Amos A, Harrison W, Keller L, Winkler AS (2022)
Characteristics of people with epilepsy in three Eastern African countries - a pooled analysis
BMC Neurol, 22 (1), 321
DOI 10.1186/s12883-022-02813-z, PubMed 36028820

Storm-Larsen C, Hande LN, Kummen M, Thunhaug H, Vestad B, Hansen SH, Hovland A, Trøseid M, Lappegård KT, Hov JR (2022)
Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
Scand J Clin Lab Invest, 82 (5), 363-370
DOI 10.1080/00365513.2022.2102540, PubMed 35913798

Størdal K, Ruiz PL, Greve-Isdahl M, Surén P, Knudsen PK, Gulseth HL, Tapia G (2022)
Risk factors for SARS-CoV-2 infection and hospitalisation in children and adolescents in Norway: a nationwide population-based study
BMJ Open, 12 (3), e056549
DOI 10.1136/bmjopen-2021-056549, PubMed 35277409

Suarez-Zdunek MA, Høgh J, Kirkegaard-Klitbo DM, Jensen AMR, Rupert A, Trøseid M, Gerstoft J, Nielsen SD, Knudsen AD (2022)
High incidence of subclinical peripheral artery disease in people with HIV
AIDS, 36 (10), 1355-1362
DOI 10.1097/QAD.0000000000003252, PubMed 35608109

Søraas A, Grødeland G, Granerud BK, Ueland T, Lind A, Fevang B, Murphy SL, Huse C, Nygaard AB, Steffensen AK, Al-Baldawi H, Holberg-Petersen M, Andresen LL, Ågnes C, Ranheim T, Schanke Y, Istre M, Dahl JA, Chopra A, Dudman S, Kaarbø M, Andersen JT, Vaage EB, Tran TT, Vaage JT et al. (2022)
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859

Søvik S, Barrat-Due A, Kåsine T, Olasveengen T, Strand MW, Tveita AA, Berdal JE, Lehre MA, Lorentsen T, Heggelund L, Stenstad T, Ringstad J, Müller F, Aukrust P, Holter JC, Nordøy I (2022)
Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation
J Infect, 85 (1), 57-63
DOI 10.1016/j.jinf.2022.05.015, PubMed 35605805

Tan YR, Agrawal A, Matsoso MP, Katz R, Davis SLM, Winkler AS, Huber A, Joshi A, El-Mohandes A, Mellado B, Mubaira CA, Canlas FC, Asiki G, Khosa H, Lazarus JV, Choisy M, Recamonde-Mendoza M, Keiser O, Okwen P, English R, Stinckwich S, Kiwuwa-Muyingo S, Kutadza T, Sethi T, Mathaha T et al. (2022)
A call for citizen science in pandemic preparedness and response: beyond data collection
BMJ Glob Health, 7 (6)
DOI 10.1136/bmjgh-2022-009389, PubMed 35760438

Tennøe AH, Murbræch K, Didriksen H, Ueland T, Palchevskiy V, Weigt SS, Fretheim H, Midtvedt Ø, Garen T, Brunborg C, Aukrust P, Molberg Ø, Belperio JA, Hoffmann-Vold AM (2022)
Serum markers of cardiac complications in a systemic sclerosis cohort
Sci Rep, 12 (1), 4661
DOI 10.1038/s41598-022-08815-8, PubMed 35304587

Thaulow CM, Berild D, Blix HS, Brigtsen AK, Myklebust TÅ, Eriksen BH (2022)
Corrigendum: Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital
Front Pediatr, 10, 862484
DOI 10.3389/fped.2022.862484, PubMed 35359886

Thaulow CM, Blix HS, Nilsen RM, Eriksen BH, Wathne JS, Berild D, Harthug S (2022)
Antibiotic use in children before, during and after hospitalisation
Pharmacoepidemiol Drug Saf, 31 (7), 749-757
DOI 10.1002/pds.5438, PubMed 35384111

Thaulow CM, Harthug S, Nilsen RM, Eriksen BH, Wathne JS, Berild D, Blix HS (2022)
Are infants exposed to antimicrobials during the first 3 months of life at increased risk of recurrent use? An explorative data-linkage study
J Antimicrob Chemother, 77 (5), 1468-1475
DOI 10.1093/jac/dkac024, PubMed 35137117

Trøseid M, Dahl TB, Holter JC, Kildal AB, Murphy SL, Yang K, Quiles-Jiménez A, Heggelund L, Müller KE, Tveita A, Michelsen AE, Bøe S, Holten AR, Hoel H, Mathiessen A, Aaløkken TM, Fevang B, Granerud BK, Tonby K, Henriksen KN, Lerum TV, Müller F, Skjønsberg OH, Barratt-Due A, Dyrhol-Riise AM et al. (2022)
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med (in press)
DOI 10.1111/joim.13549, PubMed 35982589

Trøseid M, Diallo A, Hites M, Røttingen JA, Yazdanpanah Y (2022)
Accelerating clinical trial implementation in the context of the COVID-19 pandemic: author's response
Clin Microbiol Infect, 28 (5), 743-744
DOI 10.1016/j.cmi.2021.12.014, PubMed 35031489

Trøseid M, Hentzien M, Ader F, Cardoso SW, Arribas JR, Molina JM, Mueller N, Hites M, Bonnet F, Manuel O, Costagliola D, Grinsztejn B, Olsen IC, Yazdapanah Y, Calmy A, EU RESPONSE, COMBINE (2022)
Immunocompromised patients have been neglected in COVID-19 trials: a call for action
Clin Microbiol Infect, 28 (9), 1182-1183
DOI 10.1016/j.cmi.2022.05.005, PubMed 35623577

Tunheim G, Rø GØI, Chopra A, Aase A, Kran AB, Vaage JT, Lund-Johansen F, Hungnes O (2022)
Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021
Influenza Other Respir Viruses, 16 (6), 1004-1013
DOI 10.1111/irv.13024, PubMed 35770841

Tveita A, Murphy SL, Holter JC, Kildal AB, Michelsen AE, Lerum TV, Kaarbø M, Heggelund L, Holten AR, Finbråten AK, Müller KE, Mathiessen A, Bøe S, Fevang B, Granerud BK, Tonby K, Lind A, Dudman SG, Henriksen KN, Müller F, Skjønsberg OH, Trøseid M, Barratt-Due A, Dyrhol-Riise AM, Aukrust P et al. (2022)
High circulating levels of the homeostatic chemokines CCL19 and CCL21 predict mortality and disease severity in Covid-19
J Infect Dis (in press)
DOI 10.1093/infdis/jiac313, PubMed 35876699

Ueland T, Hausberg I, Mørtberg TV, Dahl TB, Lerum TV, Michelsen A, Ranheim T, Nezvalova Henriksen K, Dyrhol-Riise AM, Holme PA, Aaløkken TM, Skjønsberg OH, Barratt-Due A, Ahlén MT, Aukrust P, Halvorsen B (2022)
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150

Uellendahl-Werth F, Maj C, Borisov O, Juzenas S, Wacker EM, Jørgensen IF, Steiert TA, Bej S, Krawitz P, Hoffmann P, Schramm C, Wolkenhauer O, Banasik K, Brunak S, Schreiber S, Karlsen TH, Degenhardt F, Nöthen M, Franke A, Folseraas T, Ellinghaus D (2022)
Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease
Commun Biol, 5 (1), 80
DOI 10.1038/s42003-022-03031-6, PubMed 35058554

Valestrand L, Zheng F, Hansen SH, Øgaard J, Hov JR, Björkström NK, Karlsen TH, Jiang X, Melum E (2022)
Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens
Am J Pathol, 192 (4), 629-641
DOI 10.1016/j.ajpath.2021.12.008, PubMed 35063408

van Hal SJ, Willems RJL, Gouliouris T, Ballard SA, Coque TM, Hammerum AM, Hegstad K, Pinholt M, Howden BP, Malhotra-Kumar S, Werner G, Yanagihara K, Earl AM, Raven KE, Corander J, Bowden R, Enterococcal Study Group (2022)
The interplay between community and hospital Enterococcus faecium clones within health-care settings: a genomic analysis
Lancet Microbe, 3 (2), e133-e141
DOI 10.1016/S2666-5247(21)00236-6, PubMed 35146465

Vazquez P, Hirayama-Shoji K, Novik S, Krauss S, Rayner S (2022)
Globally Accessible Distributed Data Sharing (GADDS): a decentralized FAIR platform to facilitate data sharing in the life sciences
Bioinformatics (in press)
DOI 10.1093/bioinformatics/btac362, PubMed 35639939

Vergaro G, Gentile F, Aimo A, Januzzi JL, Richards AM, Lam CSP, de Boer RA, Meems LMG, Latini R, Staszewsky L, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, Yoshihisa A, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K et al. (2022)
Circulating levels and prognostic cut-offs of sST2, hs-cTnT, and NT-proBNP in women vs. men with chronic heart failure
ESC Heart Fail, 9 (4), 2084-2095
DOI 10.1002/ehf2.13883, PubMed 35510529

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Vesterhus M, Jørgensen KK, Frigstad SO, Haukeland JW, Karlsen TH (2022)
We need a new strategy for liver disease
Tidsskr Nor Laegeforen, 142 (3)
DOI 10.4045/tidsskr.21.0892, PubMed 35170917

Werner MCF, Wirgenes KV, Shadrin A, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268

Werner MCF, Wirgenes KV, Shadrin AA, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598

Wiebers DO, Feigin VL, Winkler AS (2022)
All Life Protection and Our Collective Future
Neuroepidemiology, 56 (3), 147-150
DOI 10.1159/000525021, PubMed 35576913

Wæhre T, Tunheim G, Bodin JE, Laake I, Kvale D, Kran AB, Brekke H, Løken R, Oftung F, Mjaaland S, Dyrhol-Riise AM (2022)
Clinical characteristics and outcomes in hospitalized adult influenza patients: an observational study from Norway 2014-2018
Infect Dis (Lond), 54 (5), 367-377
DOI 10.1080/23744235.2021.2022196, PubMed 34983302

Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417

Publications 2021

Abraham A, Bustos JA, Carabin H, de Meijere R, Sahu PS, Rajshekhar V, Singh G, White AC, Chiodini PL, Gabriël S, Homeida M, Nash T, Ngowi B, Zhou XN, Coyle C, Garcia HH, Winkler AS (2021)
The effectiveness of anti-inflammatory and anti-seizure medication for individuals with single enhancing lesion neurocysticercosis: A meta-analysis and expert group-based consensus recommendations
PLoS Negl Trop Dis, 15 (3), e0009193
DOI 10.1371/journal.pntd.0009193, PubMed 33788843

Ahmadi A, Till K, Backe PH, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Rowe AD, Dalhus B (2021)
Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex
Commun Biol, 4 (1), 876
DOI 10.1038/s42003-021-02400-x, PubMed 34267321

Al Rubaye MTS, Janice J, Bjørnholt JV, Jakovljev A, Hultström ME, Sundsfjord A, Hegstad K (2021)
Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
PLoS One, 16 (7), e0255187
DOI 10.1371/journal.pone.0255187, PubMed 34297779

Amundsen EK, Binde C, Christensen EE, Klingenberg O, Kvale D, Holten AR (2021)
Prognostic Value of Nucleated RBCs for Patients With Suspected Sepsis in the Emergency Department: A Single-Center Prospective Cohort Study
Crit Care Explor, 3 (7), e0490
DOI 10.1097/CCE.0000000000000490, PubMed 34291222

Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I (2021)
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 1-10 (in press)
DOI 10.1017/S0033291721003056, PubMed 35387700

Aprigliano R, Aksu ME, Bradamante S, Mihaljevic B, Wang W, Rian K, Montaldo NP, Grooms KM, Fordyce Martin SL, Bordin DL, Bosshard M, Peng Y, Alexov E, Skinner C, Liabakk NB, Sullivan GJ, Bjørås M, Schwartz CE, van Loon B (2021)
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities
Cell Rep Med, 2 (4), 100240
DOI 10.1016/j.xcrm.2021.100240, PubMed 33948573

Arenas J, Szabo Z, van der Wal J, Maas C, Riaz T, Tønjum T, Tommassen J (2021)
Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin
Virulence, 12 (1), 2902-2917
DOI 10.1080/21505594.2021.2003115, PubMed 34903146

Arredondo-Alonso S, Pöntinen AK, Cléon F, Gladstone RA, Schürch AC, Johnsen PJ, Samuelsen Ø, Corander J (2021)
A high-throughput multiplexing and selection strategy to complete bacterial genomes
Gigascience, 10 (12)
DOI 10.1093/gigascience/giab079, PubMed 34891160

Arredondo-Alonso S, Top J, Corander J, Willems RJL, Schürch AC (2021)
Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals
Genome Med, 13 (1), 9
DOI 10.1186/s13073-020-00825-3, PubMed 33472670

Aukrust P, Kleveland O, Gullestad L (2021)
Targeting IL-6 Trans-Signaling: Amplifying the Benefits of IL-6 Inhibition in Myocardial Infarction
JACC Basic Transl Sci, 6 (5), 444-446
DOI 10.1016/j.jacbts.2021.01.007, PubMed 34102669

Aune SK, Byrkjeland R, Solheim S, Arnesen H, Trøseid M, Awoyemi A, Seljeflot I, Helseth R (2021)
Gut related inflammation and cardiorespiratory fitness in patients with CAD and type 2 diabetes: a sub-study of a randomized controlled trial on exercise training
Diabetol Metab Syndr, 13 (1), 36
DOI 10.1186/s13098-021-00655-2, PubMed 33794977

Aune SK, Cwikiel J, Flaa A, Arnesen H, Solheim S, Awoyemi A, Trøseid M, Seljeflot I, Helseth R (2021)
Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease
Cells, 10 (9)
DOI 10.3390/cells10092193, PubMed 34571843

Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Batisti Biffignandi G, Gibbon MJ, Corbella M, Thorpe HA, Merla C, Castelli M, Kallonen T, Pegrum K, Brisse S, Corander J, Marone P, Feil EJ, Sassera D (2021)
Genome of Superficieibacter maynardsmithii, a novel, antibiotic susceptible representative of Enterobacteriaceae
G3 (Bethesda), 11 (2)
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J Am Soc Echocardiogr, 35 (2), 243-244
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Thakur KT, Tamborska A, Wood GK, McNeill E, Roh D, Akpan IJ, Miller EC, Bautista A, Claassen J, Kim CY, Guekht A, Pardo CA, Williams O, García-Azorín D, Prasad K, Schmutzhard E, Michael BD, Chou SH, Winkler AS, Solomon T, Elkind MS (2021)
Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions
J Neurol Sci, 427, 117532
DOI 10.1016/j.jns.2021.117532, PubMed 34134058

Thaulow CM, Lindemann PC, Klingenberg C, Berild D, Salvesen Blix H, Myklebust TÅ, Harthug S (2021)
Epidemiology and Antimicrobial Susceptibility of Invasive Bacterial Infections in Children-A Population-Based Study From Norway
Pediatr Infect Dis J, 40 (5), 403-410
DOI 10.1097/INF.0000000000003013, PubMed 33298760

Thorsen IS, Gøransson LG, Ueland T, Aukrust P, Manhenke CA, Skadberg Ø, Jonsson G, Ørn S (2021)
The relationship between Fibroblast Growth Factor 23 (FGF23) and cardiac MRI findings following primary PCI in patients with acute first time STEMI
Int J Cardiol Heart Vasc, 33, 100727
DOI 10.1016/j.ijcha.2021.100727, PubMed 33665349

Thudium RF, Knudsen AD, Von Stemann JH, Hove-Skovsgaard M, Hoel H, Mocroft A, Reekie J, Ronit A, Gerstoft J, Vestbo J, Trøseid M, Borges ÁH, Ostrowski SR, Nielsen SD (2021)
Independent Association of Interleukin 6 With Low Dynamic Lung Function and Airflow Limitation in Well-Treated People With Human Immunodeficiency Virus
J Infect Dis, 223 (10), 1690-1698
DOI 10.1093/infdis/jiaa600, PubMed 33141877

Thudium RF, Ringheim H, Ronit A, Hoel H, Benfield T, Mocroft A, Gerstoft J, Trøseid M, Borges ÁH, Ostrowski SR, Vestbo J, Nielsen SD (2021)
Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV
Front Immunol, 12, 668113
DOI 10.3389/fimmu.2021.668113, PubMed 33936110

Trevisan C, Damme IV, Ngowi B, Schmidt V, Stelzle D, Møller KS, Kabululu M, Makasi CE, Magnussen P, Bottieau E, Abatih E, Johansen MV, Ngowi H, Ndawi B, Mwape KE, Zulu G, Dorny P, Winkler AS, Gabriël S, On Behalf Of The Solid Consortium (2021)
Trial Design of a Prospective Multicenter Diagnostic Accuracy Study of a Point-of-Care Test for the Detection of Taenia solium Taeniosis and Neurocysticercosis in Hospital-Based Settings in Tanzania
Diagnostics (Basel), 11 (9)
DOI 10.3390/diagnostics11091528, PubMed 34573870

Triki CC, Leonardi M, Mallouli SZ, Cacciatore M, Karlshoej KC, Magnani FG, Newton CR, Pilotto A, Saylor D, Westenberg E, Walsh D, Winkler AS, Thakur KT, Okubadejo NU, Garcia-Azorin D (2021)
Global survey on disruption and mitigation of neurological services during COVID-19: the perspective of global international neurological patients and scientific associations
J Neurol, 269 (1), 26-38
DOI 10.1007/s00415-021-10641-3, PubMed 34117527

Trøseid M, Hites M, Barratt-Due A, Ader F, Yazdanpanah Y (2021)
Assessing the evidence on remdesivir
Lancet Infect Dis, 21 (12), 1630-1631
DOI 10.1016/S1473-3099(21)00695-2, PubMed 34838222

Tunheim G, Rø GØI, Tran T, Kran AB, Andersen JT, Vaage EB, Kolderup A, Vaage JT, Lund-Johansen F, Hungnes O (2021)
Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic
Influenza Other Respir Viruses, 16 (2), 204-212
DOI 10.1111/irv.12932, PubMed 34751488

Ueland T, Abraityte A, Norum H, Varathalingam S, Gullestad L, Aukrust P, Andreassen AK (2021)
Circulating regulators of the wingless pathway in precapillary pulmonary hypertension
Respirology, 26 (6), 574-581
DOI 10.1111/resp.14048, PubMed 33830565

Ueland T, Astrup E, Otterdal K, Lekva T, Janardhanan J, Prakash JAJ, Thomas K, Michelsen AE, Aukrust P, Varghese GM, Damås JK (2021)
Secreted Wnt antagonists in scrub typhus
PLoS Negl Trop Dis, 15 (4), e0009185
DOI 10.1371/journal.pntd.0009185, PubMed 33914733

Ueland T, Dyrhol-Riise AM, Woll BM, Holten AR, Petteresen F, Lind A, Dudman SG, Heggelund L, Holter JC, Aukrust P (2021)
Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients
J Infect, 82 (5), 186-230
DOI 10.1016/j.jinf.2021.01.017, PubMed 33516748

Ueland T, Gullestad L, Kou L, Young JB, Pfeffer MA, van Veldhuisen DJ, Swedberg K, Mcmurray JJV, Desai AS, Anand IS, Aukrust P (2021)
Growth differentiation factor 15 predicts poor prognosis in patients with heart failure and reduced ejection fraction and anemia: results from RED-HF
Clin Res Cardiol, 111 (4), 440-450
DOI 10.1007/s00392-021-01944-6, PubMed 34611778

Ulvik IM, Sæthre T, Bunæs DF, Lie SA, Enersen M, Leknes KN (2021)
A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy
BMC Oral Health, 21 (1), 38
DOI 10.1186/s12903-021-01397-3, PubMed 33478480

Van Damme I, Trevisan C, Mwape KE, Schmidt V, Magnussen P, Zulu G, Mubanga C, Stelzle D, Bottieau E, Abatih E, Phiri IK, Johansen MV, Chabala C, Winkler AS, Dorny P, Gabriël S, On Behalf Of The Solid Consortium (2021)
Trial Design for a Diagnostic Accuracy Study of a Point-of-Care Test for the Detection of Taenia solium Taeniosis and (Neuro)Cysticercosis in Community Settings of Highly Endemic, Resource-Poor Areas in Zambia: Challenges and Rationale
Diagnostics (Basel), 11 (7)
DOI 10.3390/diagnostics11071138, PubMed 34206654

van Hal SJ, Willems RJL, Gouliouris T, Ballard SA, Coque TM, Hammerum AM, Hegstad K, Westh HT, Howden BP, Malhotra-Kumar S, Werner G, Yanagihara K, Earl AM, Raven KE, Corander J, Bowden R, Enterococcal Group (2021)
The global dissemination of hospital clones of Enterococcus faecium
Genome Med, 13 (1), 52
DOI 10.1186/s13073-021-00868-0, PubMed 33785076

Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693

Vergaro G, Gentile F, Meems LMG, Aimo A, Januzzi JL, Richards AM, Lam CSP, Latini R, Staszewsky L, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, Yoshihisa A, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Gamble GD et al. (2021)
NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories
JACC Heart Fail, 9 (9), 653-663
DOI 10.1016/j.jchf.2021.05.014, PubMed 34246607

Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007

Wagner M, Lorenz G, Volk AE, Brunet T, Edbauer D, Berutti R, Zhao C, Anderl-Straub S, Bertram L, Danek A, Deschauer M, Dill V, Fassbender K, Fliessbach K, Götze KS, Jahn H, Kornhuber J, Landwehrmeyer B, Lauer M, Obrig H, Prudlo J, Schneider A, Schroeter ML, Uttner I, Vukovich R et al. (2021)
Clinico-genetic findings in 509 frontotemporal dementia patients
Mol Psychiatry, 26 (10), 5824-5832
DOI 10.1038/s41380-021-01271-2, PubMed 34561610

Wang N, Anonsen JH, Hadjineophytou C, Reinar WB, Børud B, Vik Å, Koomey M (2021)
Allelic polymorphisms in a glycosyltransferase gene shape glycan repertoire in the O-linked protein glycosylation system of Neisseria
Glycobiology, 31 (4), 477-491
DOI 10.1093/glycob/cwaa073, PubMed 32776107

Watila MM, Balarabe SA, Komolafe MA, Igwe SC, Fawale MB, Otte WM, van Diessen E, Okunoye O, Mshelia AA, Abdullahi I, Musa J, Hedima EW, Nyandaiti YW, Singh G, Winkler AS, Sander JW (2021)
Epidemiology of Epilepsy in Nigeria: A Community-Based Study From 3 Sites
Neurology, 97 (7), e728-e738
DOI 10.1212/WNL.0000000000012416, PubMed 34253632

Wee BA, Alves J, Lindsay DSJ, Klatt AB, Sargison FA, Cameron RL, Pickering A, Gorzynski J, Corander J, Marttinen P, Opitz B, Smith AJ, Fitzgerald JR (2021)
Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing
Nat Commun, 12 (1), 7165
DOI 10.1038/s41467-021-27478-z, PubMed 34887398

Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Agdestein A, Tessema GT, Tønjum T, Yimer SA (2021)
Correction: Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
PLoS One, 16 (10), e0258457
DOI 10.1371/journal.pone.0258457, PubMed 34614019

Welekidan LN, Yimer SA, Skjerve E, Dejene TA, Homberset H, Tønjum T, Brynildsrud O (2021)
Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, Ethiopia
Front Microbiol, 12, 743198
DOI 10.3389/fmicb.2021.743198, PubMed 34938276

Wiebers DO, Feigin VL, Winkler AS (2021)
Brain Health, One Health, and COVID-19
Neuroepidemiology, 55 (6), 425-426
DOI 10.1159/000519372, PubMed 34634783

Winkler AS, Leonardi M, Michael BD, Abd-Allah F, Carroll W, Guekht A, Global COVID-19 Neuro Research Coalition (2021)
A WHO resolution on epilepsy and other neurological disorders
Lancet Neurol, 20 (3), 171-172
DOI 10.1016/S1474-4422(21)00026-0, PubMed 33609470

Wollen KL, Hagen L, Vågbø CB, Rabe R, Iveland TS, Aas PA, Sharma A, Sporsheim B, Erlandsen HO, Palibrk V, Bjørås M, Fonseca DM, Mosammaparast N, Slupphaug G (2021)
ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA
J Transl Med, 19 (1), 287
DOI 10.1186/s12967-021-02948-6, PubMed 34217309

Xu KQ, Chatzitakis A, Backe PH, Ruan QS, Tang JW, Rise F, Bjoras M, Norby T (2021)
In situ cofactor regeneration enables selective CO2 reduction in a stable and efficient enzymatic photoelectrochemical cell
Appl. Catal. B-Environ., 296, 120349
DOI 10.1016/j.apcatb.2021.120349

Xu KQ, Chatzitakis A, Risbakk S, Yang MY, Backe PH, Grandcolas M, Bjoras M, Norby T (2021)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catal. Today, 361, 57-62
DOI 10.1016/j.cattod.2019.12.031

Zhang Y, Shen L, Dreißigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW (2021)
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease
Blood, 137 (17), 2403-2416
DOI 10.1182/blood.2020008720, PubMed 33529322

Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, Brunak S, Buch S, Clausnitzer H, Datz C, DBDS Consortium, Degenhardt F, Doniec M, Erikstrup C, Esko T, Forster M et al. (2021)
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease
Gut, 70 (8), 1538-1549
DOI 10.1136/gutjnl-2020-323868, PubMed 33888516

Zimmer CL, von Seth E, Buggert M, Strauss O, Hertwig L, Nguyen S, Wong AYW, Zotter C, Berglin L, Michaëlsson J, Hansson MR, Arnelo U, Sparrelid E, Ellis ECS, Söderholm JD, Keita ÅV, Holm K, Özenci V, Hov JR, Mold JE, Cornillet M, Ponzetta A, Bergquist A, Björkström NK (2021)
A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells
Sci Transl Med, 13 (599)
DOI 10.1126/scitranslmed.abb3107, PubMed 34162753

Aamodt AH, Høgestøl EA, Popperud TH, Holter JC, Dyrhol-Riise AM, Tonby K, Stiksrud B, Quist-Paulsen E, Berge T, Barratt-Due A, Aukrust P, Heggelund L, Blennow K, Zetterberg H, Harbo HF (2021)
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol, 268 (10), 3574-3583
DOI 10.1007/s00415-021-10517-6, PubMed 33743046

Aarsetøy R, Ueland T, Aukrust P, Michelsen AE, de la Fuente RL, Pönitz V, Brügger-Andersen T, Grundt H, Staines H, Nilsen DWT (2021)
Angiopoietin-2 and angiopoietin-like 4 protein provide prognostic information in patients with suspected acute coronary syndrome
J Intern Med, 290 (4), 894-909
DOI 10.1111/joim.13339, PubMed 34237166

Aarsetøy R, Ueland T, Aukrust P, Michelsen AE, Leon de la Fuente R, Grundt H, Staines H, Nygaard O, Nilsen DWT (2021)
Complement component 7 is associated with total- and cardiac death in chest-pain patients with suspected acute coronary syndrome
BMC Cardiovasc Disord, 21 (1), 496
DOI 10.1186/s12872-021-02306-w, PubMed 34649504

Publications 2020

Abadpour S, Aizenshtadt A, Olsen PA, Shoji K, Wilson SR, Krauss S, Scholz H (2020)
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261

Abraham A, Schmidt V, Kaminski M, Stelzle D, De Meijere R, Bustos J, Sahu PS, Garcia HH, Bobić B, Cretu C, Chiodini P, Deksne G, Dermauw V, Devleesschauwer B, Dorny P, Fonseca A, Gabriël S, Gómez-Morales MA, Kucsera I, Laranjo-González M, Trevisan C, Vilhena M, Walker NF, Zammarchi L, Winkler AS (2020)
Epidemiology and surveillance of human (neuro)cysticercosis in Europe: is enhanced surveillance required?
Trop Med Int Health, 25 (5), 566-578
DOI 10.1111/tmi.13384, PubMed 32083787

Aimo A, Januzzi JL, Vergaro G, Richards AM, Lam CSP, Latini R, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, de Boer RA, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Gamble GD, Ling LH, Leong KTG, Yeo PSD et al. (2020)
Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T
Eur J Heart Fail, 22 (11), 2078-2088
DOI 10.1002/ejhf.1701, PubMed 31919929

Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548

Alfsnes K, Eldholm V, Olsen AO, Brynildsrud OB, Bohlin J, Steinbakk M, Caugant DA (2020)
Genomic epidemiology and population structure of Neisseria gonorrhoeae in Norway, 2016-2017
Microb Genom, 6 (4)
DOI 10.1099/mgen.0.000359, PubMed 32213251

Amuasi JH, Lucas T, Horton R, Winkler AS (2020)
Reconnecting for our future: The Lancet One Health Commission
Lancet, 395 (10235), 1469-1471
DOI 10.1016/S0140-6736(20)31027-8, PubMed 32386579

Amuasi JH, Walzer C, Heymann D, Carabin H, Huong LT, Haines A, Winkler AS (2020)
Calling for a COVID-19 One Health Research Coalition
Lancet, 395 (10236), 1543-1544
DOI 10.1016/S0140-6736(20)31028-X, PubMed 32386563

Amuasi JH, Winkler AS (2020)
One Health or Planetary Health for pandemic prevention? - Authors' reply
Lancet, 396 (10266), 1882-1883
DOI 10.1016/S0140-6736(20)32392-8, PubMed 33308466

Amundsen EK, Moholt TK, Meyer M, Haug JB, Berild D (2020)
Antibiotic stewardship with the aid of procalcitonin
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0056, PubMed 32815338

Andersen PI, Ianevski A, Lysvand H, Vitkauskiene A, Oksenych V, Bjørås M, Telling K, Lutsar I, Dumpis U, Irie Y, Tenson T, Kantele A, Kainov DE (2020)
Discovery and development of safe-in-man broad-spectrum antiviral agents
Int J Infect Dis, 93, 268-276
DOI 10.1016/j.ijid.2020.02.018, PubMed 32081774

Andersson DI, Balaban NQ, Baquero F, Courvalin P, Glaser P, Gophna U, Kishony R, Molin S, Tønjum T (2020)
Antibiotic resistance: turning evolutionary principles into clinical reality
FEMS Microbiol Rev, 44 (2), 171-188
DOI 10.1093/femsre/fuaa001, PubMed 31981358

Arain F, Abraityte A, Bogdanova M, Solberg OG, Michelsen AE, Lekva T, Aakhus S, Holm S, Halvorsen B, Finsen AV, Vinge LE, Nymo S, Espeland T, Ranheim T, Aukrust P, Vaage IJ, Auensen A, Gullestad L, Ueland T (2020)
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417

Arnold B, Sohail M, Wadsworth C, Corander J, Hanage WP, Sunyaev S, Grad YH (2020)
Fine-Scale Haplotype Structure Reveals Strong Signatures of Positive Selection in a Recombining Bacterial Pathogen
Mol Biol Evol, 37 (2), 417-428
DOI 10.1093/molbev/msz225, PubMed 31589312

Arredondo-Alonso S, Bootsma M, Hein Y, Rogers MRC, Corander J, Willems RJL, Schürch AC (2020)
gplas: a comprehensive tool for plasmid analysis using short-read graphs
Bioinformatics, 36 (12), 3874-3876
DOI 10.1093/bioinformatics/btaa233, PubMed 32271863

Aulokken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Muller F, Schubert M, Jorgensen A, Blomberg SM, Bjornerheim R, Klow NE, Hopp E (2020)
Imaging of patients with COVID-19
Tidsskr. Nor. Laegeforen., 140 (8), 756-760

Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WP (2020)
Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae
PLoS Biol, 18 (10), e3000878
DOI 10.1371/journal.pbio.3000878, PubMed 33091022

Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390

Berg A, Patel S, Tellevik MG, Haanshuus CG, Dalen I, Otterdal K, Ueland T, Moyo SJ, Aukrust P, Langeland N (2020)
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Infection, 48 (3), 367-373
DOI 10.1007/s15010-020-01399-3, PubMed 32077073

Berild D (2020)
Poor antimicrobial therapy, commendable candour
Tidsskr Nor Laegeforen, 140 (14)
DOI 10.4045/tidsskr.20.0711, PubMed 33070592

Berild D (2020)
Correction: Poor antimicrobial therapy, commendable candour
Tidsskr Nor Laegeforen, 140 (15)
DOI 10.4045/tidsskr.20.0810, PubMed 33118764

Binder K, Krauss S, Wiesner P (2020)
A New Visualization for Probabilistic Situations Containing Two Binary Events: The Frequency Net
Front Psychol, 11, 750
DOI 10.3389/fpsyg.2020.00750, PubMed 32528335

Bjoras M (2020)
Nobel Prize for discovering how cells adapt to changing oxygen levels
Tidsskr. Nor. Laegeforen., 140 (1), 8

Booth JA, Špírek M, Lobie TA, Skarstad K, Krejci L, Bjørås M (2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Sci Rep, 10 (1), 19422
DOI 10.1038/s41598-020-76426-2, PubMed 33173044

Christensen I, Haug JB, Berild D, Bjørnholt JV, Jelsness-Jørgensen LP (2020)
Hospital physicians' experiences with procalcitonin - implications for antimicrobial stewardship; a qualitative study
BMC Infect Dis, 20 (1), 515
DOI 10.1186/s12879-020-05246-6, PubMed 32677903

Colijn C, Corander J, Croucher NJ (2020)
Designing ecologically optimized pneumococcal vaccines using population genomics
Nat Microbiol, 5 (3), 473-485
DOI 10.1038/s41564-019-0651-y, PubMed 32015499

Deeb M, Karlsen TH, Hirschfield GM (2020)
The 6 C's of primary sclerosing cholangitis
J Hepatol, 73 (5), 1255-1256
DOI 10.1016/j.jhep.2020.06.033, PubMed 32649970

Derer S, Brethack AK, Pietsch C, Jendrek ST, Nitzsche T, Bokemeyer A, Hov JR, Schäffler H, Bettenworth D, Grassl GA, Sina C (2020)
Inflammatory Bowel Disease-associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria
Inflamm Bowel Dis, 26 (12), 1856-1868
DOI 10.1093/ibd/izaa069, PubMed 32304568

Dobrovolska O, Brilkov M, Madeleine N, Ødegård-Fougner Ø, Strømland Ø, Martin SR, De Marco V, Christodoulou E, Teigen K, Isaksson J, Underhaug J, Reuter N, Aalen RB, Aasland R, Halskau Ø (2020)
The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection
FEBS J, 287 (20), 4458-4480
DOI 10.1111/febs.15256, PubMed 32083791

Dorst J, Schuster J, Dreyhaupt J, Witzel S, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grehl T, Hermann A, Jordan B, Grosskreutz J, Zeller D, Boentert M, Schrank B, Prudlo J, Winkler AS, Gorbulev S, Roselli F, Dupuis L, Otto M, Ludolph AC (2020)
Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis
J Neurol Neurosurg Psychiatry, 91 (9), 1007-1009
DOI 10.1136/jnnp-2020-323372, PubMed 32788256

Farooq A, Grønmyr S, Ali O, Rognes T, Scheffler K, Bjørås M, Wang J (2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data
Comput Struct Biotechnol J, 18, 2877-2889
DOI 10.1016/j.csbj.2020.09.038, PubMed 33163148

Fitak RR, Mohandesan E, Corander J, Yadamsuren A, Chuluunbat B, Abdelhadi O, Raziq A, Nagy P, Walzer C, Faye B, Burger PA (2020)
Genomic signatures of domestication in Old World camels
Commun Biol, 3 (1), 316
DOI 10.1038/s42003-020-1039-5, PubMed 32561887

Floeystad HK, Berild JD, Brandsaeter BJ, Vestrheim DF, Berild D, Holm AM (2020)
Gastrointestinal symptoms in invasive pneumococcal disease: a cohort study
BMC Infect Dis, 20 (1), 479
DOI 10.1186/s12879-020-05211-3, PubMed 32631331

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
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Otterdal K, Berg A, Michelsen AE, Patel S, Gregersen I, Sagen EL, Halvorsen B, Yndestad A, Ueland T, Langeland N, Aukrust P (2020)
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363

Pensar J, Xu YY, Puranen S, Pesonen M, Kabashima Y, Corander J (2020)
High-dimensional structure learning of binary pairwise Markov networks: A comparative numerical study
Comput. Stat. Data Anal., 141, 62-76
DOI 10.1016/j.csda.2019.06.012

Perdreau-Dahl H, Progida C, Barfeld SJ, Guldsten H, Thiede B, Arntzen M, Bakke O, Mills IG, Krauss S, Morth JP (2020)
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109

Pihlstrøm HK, Ueland T, Michelsen AE, Aukrust P, Gatti F, Hammarström C, Kasprzycka M, Wang J, Haraldsen G, Mjøen G, Dahle DO, Midtvedt K, Eide IA, Hartmann A, Holdaas H (2020)
Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients
PLoS One, 15 (12), e0243759
DOI 10.1371/journal.pone.0243759, PubMed 33326471

Połeć A, Rowe AD, Blicher P, Suganthan R, Bjørås M, Bøe SO (2020)
PML Regulates the Epidermal Differentiation Complex and Skin Morphogenesis during Mouse Embryogenesis
Genes (Basel), 11 (10)
DOI 10.3390/genes11101130, PubMed 32992884

Prodjinotho UF, Lema J, Lacorcia M, Schmidt V, Vejzagic N, Sikasunge C, Ngowi B, Winkler AS, Prazeres da Costa C (2020)
Host immune responses during Taenia solium Neurocysticercosis infection and treatment
PLoS Negl Trop Dis, 14 (4), e0008005
DOI 10.1371/journal.pntd.0008005, PubMed 32298263

Quiles-Jiménez A, Gregersen I, Mittelstedt Leal de Sousa M, Abbas A, Kong XY, Alseth I, Holm S, Dahl TB, Skagen K, Skjelland M, Aukrust P, Bjørås M, Halvorsen B (2020)
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177

Radovanovic D, Hoist C, Belur SB, Srivastava R, Houngbonon GV, Le Quentrec E, Miliza J, Winkler AS, Noll J (2020)
Digital Literacy Key Performance Indicators for Sustainable Development
Soc. Incl., 8 (2), 151-167
DOI 10.17645/si.v8i2.2587

Rajar P, Saugstad OD, Berild D, Dutta A, Greisen G, Lausten-Thomsen U, Mande SS, Nangia S, Petersen FC, Dahle UR, Haaland K (2020)
Antibiotic Stewardship in Premature Infants: A Systematic Review
Neonatology, 117 (6), 673-686
DOI 10.1159/000511710, PubMed 33271554

Ramstad SN, Taxt AM, Naseer U, Wasteson Y, Bjørnholt JV, Brandal LT (2020)
Effects of antimicrobials on Shiga toxin production in high-virulent Shiga toxin-producing Escherichia coli
Microb Pathog, 152, 104636
DOI 10.1016/j.micpath.2020.104636, PubMed 33242644

Reikvam DH, Meyer-Myklestad MH, Trøseid M, Stiksrud B (2020)
Probiotics to manage inflammation in HIV infection
Curr Opin Infect Dis, 33 (1), 34-43
DOI 10.1097/QCO.0000000000000612, PubMed 31789692

Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T (2020)
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070

Rodriguez-Vargas JM, Martin-Hernandez K, Wang W, Kunath N, Suganthan R, Amé JC, Oliver FJ, Ye J, Bjørås M, Dantzer F (2020)
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
Cell Death Dis, 11 (11), 954
DOI 10.1038/s41419-020-03167-5, PubMed 33159039

Rojahn AE, Gammelsrud KW, Brunvand LI, Hanche-Olsen TP, Schistad O, Sæter CB, Haaland K (2020)
Multiorgan inflammatory syndrome associated with SARS-CoV-2 in a child
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0485, PubMed 32815352

Rojahn AE, Gammelsrud KW, Brunvand LI, Hanche-Olsen TP, Schistad O, Sæter CB, Haaland K (2020)
Rettelse: Multiorgan inflammatorisk syndrom assosiert med sars-CoV-2 hos et barn
Tidsskr Nor Laegeforen, 140
DOI 10.4045/tidsskr.20.0576, PubMed 32815359

Sahaf Naeini A, Farooq A, Bjørås M, Wang J (2020)
IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity
Comput Struct Biotechnol J, 18, 1270-1286
DOI 10.1016/j.csbj.2020.05.024, PubMed 32612751

Scheffler K, Jalland CMO, Benestad SL, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis MA (2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Free Radic Biol Med, 152, 348-354
DOI 10.1016/j.freeradbiomed.2020.03.030, PubMed 32259578

Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
N Engl J Med, 383 (16), 1522-1534
DOI 10.1056/NEJMoa2020283, PubMed 32558485

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482

Stelzle D, Tanaka LF, Lee KK, Ibrahim Khalil A, Baussano I, Shah ASV, McAllister DA, Gottlieb SL, Klug SJ, Winkler AS, Bray F, Baggaley R, Clifford GM, Broutet N, Dalal S (2020)
Estimates of the global burden of cervical cancer associated with HIV
Lancet Glob Health, 9 (2), e161-e169
DOI 10.1016/S2214-109X(20)30459-9, PubMed 33212031

Strand J, Gul KA, Erichsen HC, Lundman E, Berge MC, Trømborg AK, Sørgjerd LK, Ytre-Arne M, Hogner S, Halsne R, Gaup HJ, Osnes LT, Kro GAB, Sorte HS, Mørkrid L, Rowe AD, Tangeraas T, Jørgensen JV, Alme C, Bjørndalen TEH, Rønnestad AE, Lang AM, Rootwelt T, Buechner J, Øverland T et al. (2020)
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152

Szabo A, Akkouh IA, Ueland T, Lagerberg TV, Dieset I, Bjella T, Aukrust P, Le Hellard S, Stavrum AK, Melle I, Andreassen OA, Djurovic S (2020)
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224

Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem, 296, 100179
DOI 10.1074/jbc.RA120.015285, PubMed 33303632

Taxt AM, Grødeland G, Lind A, Müller F (2020)
Status of COVID-19 vaccine development
Tidsskr Nor Laegeforen, 140 (13)
DOI 10.4045/tidsskr.20.0676, PubMed 32998488

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Nature, 583 (7814), 90-95
DOI 10.1038/s41586-020-2265-1, PubMed 32499645

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Nature, 584 (7819), E2
DOI 10.1038/s41586-020-2556-6, PubMed 32678341

Tholin B, Hauge MT, Aukrust P, Fehrle L, Tvedt TH (2020)
Hemophagocytic lymphohistiocytosis in a patient with COVID-19 treated with tocilizumab: a case report
J Med Case Rep, 14 (1), 187
DOI 10.1186/s13256-020-02503-9, PubMed 33054818

Tollånes MC, Bakken Kran AM, Abildsnes E, Jenum PA, Breivik AC, Sandberg S (2020)
Evaluation of eleven rapid tests for detection of antibodies against SARS-CoV-2
Clin Chem Lab Med, 58 (9), 1595-1600
DOI 10.1515/cclm-2020-0628, PubMed 32598303

Tonkin-Hill G, MacAlasdair N, Ruis C, Weimann A, Horesh G, Lees JA, Gladstone RA, Lo S, Beaudoin C, Floto RA, Frost SDW, Corander J, Bentley SD, Parkhill J (2020)
Producing polished prokaryotic pangenomes with the Panaroo pipeline
Genome Biol, 21 (1), 180
DOI 10.1186/s13059-020-02090-4, PubMed 32698896

Top J, Arredondo-Alonso S, Schürch AC, Puranen S, Pesonen M, Pensar J, Willems RJL, Corander J (2020)
Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen, Enterococcus faecium
Microb Genom, 6 (12)
DOI 10.1099/mgen.0.000488, PubMed 33253085

Trøseid M (2020)
When COVID-19 meets the African health service
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0283, PubMed 32378852

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Trøseid M, Lutro O, Ormaasen V (2020)
Experimental treatment for COVID-19 should be undertaken in randomised studies
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0282, PubMed 32378863

Tveiten H, Aukrust P, Lehne G, Rodriguez JR, Skjønsberg OH (2020)
Haemophagocytic lymphohistiocytosis in COVID-19 cases?
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.20.0240, PubMed 32321221

Tveiten H, Lehne G, Aukrust P, Rodriguez JR, Skjønsberg OH (2020)
A man in his forties with increasing shortness of breath
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.19.0692, PubMed 32321231

Ueland T, Estensen ME, Grindheim G, Bollerslev J, Henriksen T, Aukrust P, Aakhus S, Gullestad L, Lekva T (2020)
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Ueland T, Holter JC, Holten AR, Müller KE, Lind A, Bekken GK, Dudman S, Aukrust P, Dyrhol-Riise AM, Heggelund L (2020)
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675

Ueland T, Roland MCP, Michelsen AE, Godang K, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2020)
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383

Ulvestad E, Kommedal Ø, Simonsen GS, Müller F, Leegaard TM, Löhr IH, Nordbø SA (2020)
Norway’s microbiological preparedness under threat
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0451, PubMed 32815358

Valestrand L, Berntsen NL, Zheng F, Schrumpf E, Hansen SH, Karlsen TH, Blumberg RS, Hov JR, Jiang X, Melum E (2020)
Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
Clin Exp Immunol, 203 (2), 304-314
DOI 10.1111/cei.13541, PubMed 33089489

Vesterhus M, Karlsen TH (2020)
Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
J Gastroenterol, 55 (6), 588-614
DOI 10.1007/s00535-020-01681-z, PubMed 32222826

Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2020)
Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
JHEP Rep, 3 (1), 100178
DOI 10.1016/j.jhepr.2020.100178, PubMed 33225252

Wang H, Kuusela S, Rinnankoski-Tuikka R, Dumont V, Bouslama R, Ramadan UA, Waaler J, Linden AM, Chi NW, Krauss S, Pirinen E, Lehtonen S (2020)
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Int J Obes (Lond), 44 (8), 1691-1702
DOI 10.1038/s41366-020-0573-z, PubMed 32317752

Watila MM, Balarabe SA, Komolafe M, Igwe SC, Bimbo Fawale M, van Diessen E, Nyandaiti YW, Singh G, Winkler AS, Sander JW (2020)
Translation and validation of an epilepsy-screening questionnaire in three Nigerian languages
Epilepsy Behav, 114 (Pt A), 107604
DOI 10.1016/j.yebeh.2020.107604, PubMed 33268016

Wedervang-Resell K, Ueland T, Aukrust P, Friis S, Holven KB, H Johannessen C, Lekva T, Lonning V, Smelror RE, Szabo A, Andreassen OA, Myhre AM, Agartz I (2020)
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840

Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Agdestein A, Tessema GT, Tønjum T, Yimer SA (2020)
Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
PLoS One, 15 (8), e0236362
DOI 10.1371/journal.pone.0236362, PubMed 32797053

Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Tønjum T, Yimer SA (2020)
Frequency and patterns of first- and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in a cross-sectional study in Tigray Region, Ethiopia
J Glob Antimicrob Resist, 24, 6-13
DOI 10.1016/j.jgar.2020.11.017, PubMed 33279682

WHO Solidarity Trial Consortium, Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Abdool Karim Q, Alejandria MM, Hernández García C, Kieny MP, Malekzadeh R, Murthy S, Reddy KS, Roses Periago M, Abi Hanna P, Ader F, Al-Bader AM, Alhasawi A, Allum E, Alotaibi A, Alvarez-Moreno CA, Appadoo S, Asiri A, Aukrust P, Barratt-Due A et al. (2020)
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556

Winkler AS, Knauss S, Schmutzhard E, Leonardi M, Padovani A, Abd-Allah F, Charway-Felli A, Emmrich JV, Umapathi T, Satishchandra P, Hoo FK, Dalmau J, Oreja-Guevara C, Ferreira MLB, Pfausler B, Michael BD, Tagliavini F, Höglinger G, Endres M, Klein C, Hemmer B, Carroll W, Sejvar J, Solomon T (2020)
A call for a global COVID-19 Neuro Research Coalition
Lancet Neurol, 19 (6), 482-484
DOI 10.1016/S1474-4422(20)30150-2, PubMed 32470416

Waaler J, Leenders RGG, Sowa ST, Alam Brinch S, Lycke M, Nieczypor P, Aertssen S, Murthy S, Galera-Prat A, Damen E, Wegert A, Nazaré M, Lehtiö L, Krauss S (2020)
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
J Med Chem, 63 (13), 6834-6846
DOI 10.1021/acs.jmedchem.0c00208, PubMed 32511917

Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

Yaqub S, Rana MU, Aukrust P (2020)
Ramadan under covid-19-pandemien
Tidsskr Nor Laegeforen, 140
DOI 10.4045/tidsskr.20.0390, PubMed 32378869

Yimer SA, Kalayou S, Homberset H, Birhanu AG, Riaz T, Zegeye ED, Lutter T, Abebe M, Holm-Hansen C, Aseffa A, Tønjum T (2020)
Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
Front Microbiol, 11, 550760
DOI 10.3389/fmicb.2020.550760, PubMed 33072011

Aalto-Araneda M, Pöntinen A, Pesonen M, Corander J, Markkula A, Tasara T, Stephan R, Korkeala H (2020)
Strain Variability of Listeria monocytogenes under NaCl Stress Elucidated by a High-Throughput Microbial Growth Data Assembly and Analysis Protocol
Appl Environ Microbiol, 86 (6)
DOI 10.1128/AEM.02378-19, PubMed 31900307

Aaløkken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Müller F, Schubert M, Jørgensen A, Blomberg SM, Bjørnerheim R, Kløw NE, Hopp E (2020)
Diagnostic imaging of COVID-19 patients
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0332, PubMed 32463192

Aamodt AH, Flinstad Harbo H, Eldøen G, Barratt-Due A, Aukrust P (2020)
How does COVID-19 affect the brain?
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0444, PubMed 32602331

Publications 2019

Abrahamsen TG (2019)
Helping on call paediatricians to identify acute primary immunodeficiency diseases
Acta Paediatr, 108 (12), 2127-2128
DOI 10.1111/apa.15000, PubMed 31621102

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2019)
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 10 (1), 1991
DOI 10.1038/s41467-019-10070-x, PubMed 31024006

Ahmadi A, Till K, Hafting Y, Schüttpelz M, Bjørås M, Glette K, Tørresen J, Rowe AD, Dalhus B (2019)
Additive manufacturing of laminar flow cells for single-molecule experiments
Sci Rep, 9 (1), 16784
DOI 10.1038/s41598-019-53151-z, PubMed 31727950

Andersen PI, Krpina K, Ianevski A, Shtaida N, Jo E, Yang J, Koit S, Tenson T, Hukkanen V, Anthonsen MW, Bjoras M, Evander M, Windisch MP, Zusinaite E, Kainov DE (2019)
Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine
Viruses, 11 (10)
DOI 10.3390/v11100964, PubMed 31635418

Andersen T, Ueland T, Ghukasyan Lakic T, Åkerblom A, Bertilsson M, Aukrust P, Michelsen AE, James SK, Becker RC, Storey RF, Wallentin L, Siegbahn A, Kontny F (2019)
C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (11), 2402-2410
DOI 10.1161/ATVBAHA.119.312633, PubMed 31554419

Anstensrud AK, Woxholt S, Sharma K, Broch K, Bendz B, Aakhus S, Ueland T, Amundsen BH, Damås JK, Hopp E, Kleveland O, Stensæth KH, Opdahl A, Kløw NE, Seljeflot I, Andersen GØ, Wiseth R, Aukrust P, Gullestad L (2019)
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391

Arredondo-Alonso S, Rogers MRC, Braat JC, Verschuuren TD, Top J, Corander J, Willems RJL, Schürch AC (2019)
Corrigendum: mlplasmids: a user-friendly tool to predict plasmid- and chromosome-derived sequences for single species
Microb Genom, 5 (1)
DOI 10.1099/mgen.0.000249, PubMed 30714567

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2019)
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620

Berdal JE, Follin-Arbelet B, Bjørnholt JV (2019)
Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter
BMC Infect Dis, 19 (1), 630
DOI 10.1186/s12879-019-4271-1, PubMed 31315581

Berges N, Nawaz MS, Børresdatter Dahl T, Hagen L, Bjørås M, Laerdahl JK, Alseth I (2019)
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
PLoS One, 14 (11), e0225081
DOI 10.1371/journal.pone.0225081, PubMed 31703097

Berry JL, Gurung I, Anonsen JH, Spielman I, Harper E, Hall AMJ, Goosens VJ, Raynaud C, Koomey M, Biais N, Matthews S, Pelicic V (2019)
Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis
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Narverud I, Bogsrud MP, Øyri LKL, Ulven SM, Retterstøl K, Ueland T, Mulder M, Roeters van Lennep J, Halvorsen B, Aukrust P, Veierød MB, Holven KB (2019)
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370

Narverud I, Christensen JJ, Bakke SS, Ulven SM, Rundblad A, Aukrust P, Espevik T, Bogsrud MP, Retterstøl K, Ueland T, Halvorsen B, Holven KB (2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426

Ngowi HA, Winkler AS, Braae UC, Mdegela RH, Mkupasi EM, Kabululu ML, Lekule FP, Johansen MV (2019)
Taenia solium taeniosis and cysticercosis literature in Tanzania provides research evidence justification for control: A systematic scoping review
PLoS One, 14 (6), e0217420
DOI 10.1371/journal.pone.0217420, PubMed 31166983

Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
J Biol Chem, 294 (49), 18784-18795
DOI 10.1074/jbc.RA119.009721, PubMed 31676685

Nome ME, Euceda LR, Jabeen S, Debik J, Bathen TF, Giskeødegård GF, Taskén KA, Maelandsmo GM, Halvorsen B, Yndestad A, Borgen E, Garred Ø, Aukrust P, Ueland T, Engebraaten O, Kristensen VN, Tekpli X (2019)
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972

Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T (2019)
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol, 197 (1), 74-82
DOI 10.1111/cei.13283, PubMed 30821848

Nymoen Aasbrenn M, Skeie I, Berild D (2019)
Compliance to antibiotic guidelines leads to more appropriate use of antibiotics in skin and soft tissue infections in injecting drug users
Infect Dis (Lond), 51 (8), 570-577
DOI 10.1080/23744235.2019.1617435, PubMed 31144548

Paraskevis D, Beloukas A, Stasinos K, Pantazis N, de Mendoza C, Bannert N, Meyer L, Zangerle R, Gill J, Prins M, d'Arminio Montforte A, Kran AB, Porter K, Touloumi G, CASCADE collaboration of EuroCoord (2019)
HIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors
BMC Med, 17 (1), 4
DOI 10.1186/s12916-018-1241-1, PubMed 30616632

Pensar J, Puranen S, Arnold B, MacAlasdair N, Kuronen J, Tonkin-Hill G, Pesonen M, Xu Y, Sipola A, Sánchez-Busó L, Lees JA, Chewapreecha C, Bentley SD, Harris SR, Parkhill J, Croucher NJ, Corander J (2019)
Genome-wide epistasis and co-selection study using mutual information
Nucleic Acids Res, 47 (18), e112
DOI 10.1093/nar/gkz656, PubMed 31361894

Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131

Quist-Paulsen E, Kran AB, Lindland ES, Ellefsen K, Sandvik L, Dunlop O, Ormaasen V (2019)
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985

Quist-Paulsen E, Ormaasen V, Kran AB, Dunlop O, Ueland PM, Ueland T, Eikeland R, Aukrust P, Nordenmark TH (2019)
Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning
Sci Rep, 9 (1), 16158
DOI 10.1038/s41598-019-52570-2, PubMed 31695095

Roaldsnes E, Eikeland R, Berild D (2019)
Lyme borreliosis and antibiotic therapy
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0222, PubMed 30969057

Roaldsnes E, Eikeland R, Berild D (2019)
Lyme disease and antibiotic treatment
Tidsskr. Nor. Laegeforen., 139 (7), 586

Rusthen S, Kristoffersen AK, Young A, Galtung HK, Petrovski BÉ, Palm Ø, Enersen M, Jensen JL (2019)
Dysbiotic salivary microbiota in dry mouth and primary Sjögren's syndrome patients
PLoS One, 14 (6), e0218319
DOI 10.1371/journal.pone.0218319, PubMed 31211815

Rühlemann MC, Solovjeva MEL, Zenouzi R, Liwinski T, Kummen M, Lieb W, Hov JR, Schramm C, Franke A, Bang C (2019)
Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
Gut, 69 (10), 1890-1892
DOI 10.1136/gutjnl-2019-320008, PubMed 31653787

Rørslett Hardersen L, Enersen M, Kristoffersen AK, Ørstavik D, Sunde PT (2019)
Maintenance of the aseptic working field during endodontic treatment
Acta Odontol Scand, 77 (7), 502-507
DOI 10.1080/00016357.2019.1606935, PubMed 31094270

Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
Eur J Clin Invest, 49 (5), e13088
DOI 10.1111/eci.13088, PubMed 30762236

Sánchez-Busó L, Golparian D, Corander J, Grad YH, Ohnishi M, Flemming R, Parkhill J, Bentley SD, Unemo M, Harris SR (2019)
The impact of antimicrobials on gonococcal evolution
Nat Microbiol, 4 (11), 1941-1950
DOI 10.1038/s41564-019-0501-y, PubMed 31358980

Schaufler K, Semmler T, Wieler LH, Trott DJ, Pitout J, Peirano G, Bonnedahl J, Dolejska M, Literak I, Fuchs S, Ahmed N, Grobbel M, Torres C, McNally A, Pickard D, Ewers C, Croucher NJ, Corander J, Guenther S (2019)
Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.00243-19, PubMed 30885899

Scheffler K, Bjørås KØ, Bjørås M (2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain
DNA Repair (Amst), 81, 102665
DOI 10.1016/j.dnarep.2019.102665, PubMed 31327582

Schmidt V, O'Hara MC, Ngowi B, Herbinger KH, Noh J, Wilkins PP, Richter V, Kositz C, Matuja W, Winkler AS (2019)
Taenia solium cysticercosis and taeniasis in urban settings: Epidemiological evidence from a health-center based study among people with epilepsy in Dar es Salaam, Tanzania
PLoS Negl Trop Dis, 13 (12), e0007751
DOI 10.1371/journal.pntd.0007751, PubMed 31809501

Schneditz G, Elias JE, Pagano E, Zaeem Cader M, Saveljeva S, Long K, Mukhopadhyay S, Arasteh M, Lawley TD, Dougan G, Bassett A, Karlsen TH, Kaser A, Kaneider NC (2019)
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
Sci Signal, 12 (562)
DOI 10.1126/scisignal.aau9048, PubMed 30600262

Shahini N, Ueland T, Auensen A, Michelsen AE, Ludviksen JK, Hussain AI, Pettersen KI, Aakhus S, Espeland T, Lunde IG, Kirschfink M, Nilsson PH, Mollnes TE, Gullestad L, Aukrust P, Yndestad A, Louwe MC (2019)
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744

Shi W, Cui P, Niu H, Zhang S, Tønjum T, Zhu B, Zhang Y (2019)
Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.02681-18, PubMed 30858213

Siljan WW, Holter JC, Michelsen AE, Nymo SH, Lauritzen T, Oppen K, Husebye E, Ueland T, Mollnes TE, Aukrust P, Heggelund L (2019)
Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study
ERJ Open Res, 5 (1)
DOI 10.1183/23120541.00014-2019, PubMed 30863773

Smet A, Yahara K, Rossi M, Tay A, Backert S, Ensser A, Fox JG, Flahou B, Ducatelle R, Haesebrouck F, Corander J (2019)
Correction: Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence
ISME J, 13 (7), 1890
DOI 10.1038/s41396-019-0380-5, PubMed 30820036

Sokolova M, Ranheim T, Louwe MC, Halvorsen B, Yndestad A, Aukrust P (2019)
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530

Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang L, Haugstad SB, Bendiksen BA, Øgaard J, Bliksøen M, Lien E, Berge RK, Aukrust P, Ranheim T, Yndestad A (2019)
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
Front Immunol, 10, 1621
DOI 10.3389/fimmu.2019.01621, PubMed 31379826

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Solberg OG, Stavem K, Ragnarsson A, Beitnes JO, Skårdal R, Seljeflot I, Ueland T, Aukrust P, Gullestad L, Aaberge L (2019)
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv, 94 (5), 660-668
DOI 10.1002/ccd.28157, PubMed 30790446

Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356

Storm-Larsen C, Myhr KM, Farbu E, Midgard R, Nyquist K, Broch L, Berg-Hansen P, Buness A, Holm K, Ueland T, Fallang LE, Burum-Auensen E, Hov JR, Holmøy T (2019)
Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
DOI 10.1177/2055217319888767, PubMed 31798939

Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315

Thaulow CM, Berild D, Blix HS, Brigtsen AK, Myklebust TÅ, Eriksen BH (2019)
Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital
Front Pediatr, 7, 440
DOI 10.3389/fped.2019.00440, PubMed 31709209

Thaulow CM, Berild D, Eriksen BH, Myklebust TÅ, Blix HS (2019)
Potential for More Rational Use of Antibiotics in Hospitalized Children in a Country With Low Resistance: Data From eight Point Prevalence Surveys
Pediatr Infect Dis J, 38 (4), 384-389
DOI 10.1097/INF.0000000000002106, PubMed 30882728

Thaulow CM, Blix HS, Eriksen BH, Ask I, Myklebust TÅ, Berild D (2019)
Using a period incidence survey to compare antibiotic use in children between a university hospital and a district hospital in a country with low antimicrobial resistance: a prospective observational study
BMJ Open, 9 (5), e027836
DOI 10.1136/bmjopen-2018-027836, PubMed 31138583

Thingholm LB, Rühlemann MC, Koch M, Fuqua B, Laucke G, Boehm R, Bang C, Franzosa EA, Hübenthal M, Rahnavard A, Frost F, Lloyd-Price J, Schirmer M, Lusis AJ, Vulpe CD, Lerch MM, Homuth G, Kacprowski T, Schmidt CO, Nöthlings U, Karlsen TH, Lieb W, Laudes M, Franke A, Huttenhower C (2019)
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
Cell Host Microbe, 26 (2), 252-264.e10
DOI 10.1016/j.chom.2019.07.004, PubMed 31399369

Thurn T, Borasio GD, Chiò A, Galvin M, McDermott CJ, Mora G, Sermeus W, Winkler AS, Anneser J (2019)
Physicians' attitudes toward end-of-life decisions in amyotrophic lateral sclerosis
Amyotroph Lateral Scler Frontotemporal Degener, 20 (1-2), 74-81
DOI 10.1080/21678421.2018.1536154, PubMed 30789031

Todorovic M, Gutmann MU, Corander J, Rinke P (2019)
Bayesian inference of atomistic structure in functional materials
npj Comput. Mater., 5, 35
DOI 10.1038/s41524-019-0175-2

Tonby K, Mortensen R, Ruhwald M, Dyrhol-Riise AM, Jenum S (2019)
KLRG1-Expressing CD4 T Cells Are Reduced in Tuberculosis Patients Compared to Healthy Mycobacterium tuberculosis-Infected Subjects, but Increase With Treatment
J Infect Dis, 220 (1), 174-176
DOI 10.1093/infdis/jiz056, PubMed 30888024

Tonkin-Hill G, Lees JA, Bentley SD, Frost SDW, Corander J (2019)
Fast hierarchical Bayesian analysis of population structure
Nucleic Acids Res, 47 (11), 5539-5549
DOI 10.1093/nar/gkz361, PubMed 31076776

Torp MK, Yang K, Ranheim T, Husø Lauritzen K, Alfsnes K, Vinge LE, Aukrust P, Stensløkken KO, Yndestad A, Sandanger Ø (2019)
Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts
Front Immunol, 10, 1285
DOI 10.3389/fimmu.2019.01285, PubMed 31244838

Trevisan C, Sotiraki S, Laranjo-González M, Dermauw V, Wang Z, Kärssin A, Cvetkovikj A, Winkler AS, Abraham A, Bobić B, Lassen B, Cretu CM, Vasile C, Arvanitis D, Deksne G, Boro I, Kucsera I, Karamon J, Stefanovska J, Koudela B, Pavlova MJ, Varady M, Pavlak M, Šarkūnas M, Kaminski M et al. (2019)
Correction to: Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe
Parasit Vectors, 12 (1), 84
DOI 10.1186/s13071-019-3328-8, PubMed 30777134

Troseid M (2019)
Bone Marrow Transplantation - a cure for HIV?
Tidsskr. Nor. Laegeforen., 139 (7), 580

Trøseid M (2019)
Bone marrow transplantation – a cure for HIV?
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0199, PubMed 30969050

Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965

Tschirhart N, Straiton M, Ottersen T, Winkler AS (2019)
"Living like I am in Thailand": stress and coping strategies among Thai migrant masseuses in Oslo, Norway
BMC Womens Health, 19 (1), 139
DOI 10.1186/s12905-019-0836-9, PubMed 31729987

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, Aukrust P, Christensen G, Skjønsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936

Ueland T, Aukrust P, Caidahl K (2019)
CCL21 and prognosis in acute coronary syndrome
Aging (Albany NY), 11 (21), 9225-9226
DOI 10.18632/aging.102443, PubMed 31694981

Ueland T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2019)
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Budaj A, Cornel JH, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L, PLATO Investigators (2019)
ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial
Atherosclerosis, 293, 35-41
DOI 10.1016/j.atherosclerosis.2019.11.031, PubMed 31835039

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L, PLATO Investigators (2019)
Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (2), 294-302
DOI 10.1161/ATVBAHA.118.311042, PubMed 30580572

van der Vorst EPC, Daissormont I, Aslani M, Seijkens T, Wijnands E, Lutgens E, Duchene J, Santovito D, Döring Y, Halvorsen B, Aukrust P, Weber C, Höpken UE, Biessen EAL (2019)
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development
Thromb Haemost, 120 (2), 344-347
DOI 10.1055/s-0039-3400746, PubMed 31837653

Vorkapic D, Mitterer F, Pressler K, Leitner DR, Anonsen JH, Liesinger L, Mauerhofer LM, Kuehnast T, Toeglhofer M, Schulze A, Zingl FG, Feldman MF, Reidl J, Birner-Gruenberger R, Koomey M, Schild S (2019)
A Broad Spectrum Protein Glycosylation System Influences Type II Protein Secretion and Associated Phenotypes in Vibrio cholerae
Front Microbiol, 10, 2780
DOI 10.3389/fmicb.2019.02780, PubMed 31849912

Wailan AM, Coll F, Heinz E, Tonkin-Hill G, Corander J, Feasey NA, Thomson NR (2019)
rPinecone: Define sub-lineages of a clonal expansion via a phylogenetic tree
Microb Genom, 5 (4)
DOI 10.1099/mgen.0.000264, PubMed 30920366

Watila MM, Xiao F, Keezer MR, Miserocchi A, Winkler AS, McEvoy AW, Sander JW (2019)
Epilepsy surgery in low- and middle-income countries: A scoping review
Epilepsy Behav, 92, 311-326
DOI 10.1016/j.yebeh.2019.01.001, PubMed 30738248

Wedervang-Resell K, Friis S, Lonning V, Smelror RE, Johannessen C, Reponen EJ, Lyngstad SH, Lekva T, Aukrust P, Ueland T, Andreassen OA, Agartz I, Myhre AM (2019)
Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
DOI 10.1016/j.psyneuen.2019.104513, PubMed 31761332

Weinert LA, Chaudhuri RR, Wang J, Peters SE, Corander J, Jombart T, Baig A, Howell KJ, Vehkala M, Välimäki N, Harris D, Chieu TTB, Van Vinh Chau N, Campbell J, Schultsz C, Parkhill J, Bentley SD, Langford PR, Rycroft AN, Wren BW, Farrar J, Baker S, Hoa NT, Holden MTG, Tucker AW et al. (2019)
Publisher Correction: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis
Nat Commun, 10 (1), 5326
DOI 10.1038/s41467-019-13138-w, PubMed 31757940

Winkler AS (2019)
The growing burden of neurological disorders in low-income and middle-income countries: priorities for policy making
Lancet Neurol, 19 (3), 200-202
DOI 10.1016/S1474-4422(19)30476-4, PubMed 31813849

Xu K, Chatzitakis A, Risbakk S, Yang M, Backe PH, Grandcolas M, Bjørås M, Norby T (2019)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catalysis Today, 0, 1-6 (in press)
DOI 10.1016/j.cattod.2019.12.031, PublikaID 337

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD⁺ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

Zandi H, Petronijevic N, Mdala I, Kristoffersen AK, Enersen M, Rôças IN, Siqueira JF, Ørstavik D (2019)
Outcome of Endodontic Retreatment Using 2 Root Canal Irrigants and Influence of Infection on Healing as Determined by a Molecular Method: A Randomized Clinical Trial
J Endod, 45 (9), 1089-1098.e5
DOI 10.1016/j.joen.2019.05.021, PubMed 31300248

Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, 104 (5), e229
DOI 10.3324/haematol.2019.220533, PubMed 31040234

Zhang Z, Manaf A, Li Y, Perez SP, Suganthan R, Dahl JA, Bjørås M, Klungland A (2019)
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
Mol Neurobiol, 57 (2), 997-1008
DOI 10.1007/s12035-019-01777-5, PubMed 31654318

Zöllner R, Cronenberg T, Kouzel N, Welker A, Koomey M, Maier B (2019)
Type IV Pilin Post-Translational Modifications Modulate Material Properties of Bacterial Colonies
Biophys J, 116 (5), 938-947
DOI 10.1016/j.bpj.2019.01.020, PubMed 30739725

Publications 2018

Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H (2018)
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151

Abraityte A, Aukrust P, Kou L, Anand IS, Young J, Mcmurray JJV, van Veldhuisen DJ, Gullestad L, Ueland T (2018)
T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF
Clin Res Cardiol, 108 (2), 133-141
DOI 10.1007/s00392-018-1331-2, PubMed 30051179

Abudahab K, Prada JM, Yang Z, Bentley SD, Croucher NJ, Corander J, Aanensen DM (2018)
PANINI: Pangenome Neighbour Identification for Bacterial Populations
Microb Genom, 5 (4)
DOI 10.1099/mgen.0.000220, PubMed 30465642

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2018)
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 9 (1), 5381
DOI 10.1038/s41467-018-07797-4, PubMed 30568191

Alexeeva M, Guragain P, Tesfahun AN, Tomkuvienė M, Arshad A, Gerasimaitė R, Rukšėnaitė A, Urbanavičiūtė G, Bjørås M, Laerdahl JK, Klungland A, Klimašauskas S, Bjelland S (2018)
Excision of the doubly methylated base N⁴,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Philos Trans R Soc Lond B Biol Sci, 373 (1748)
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DOI 10.3390/jof4010029, PubMed 29466284

Nordøy I, Lutro O, Longva JÅ, Bekken GK, Simonsen HE (2018)
Outdated guidelines on antibiotic use
Tidsskr Nor Laegeforen, 138 (18)
DOI 10.4045/tidsskr.18.0817, PubMed 30421740

Norum HM, Michelsen AE, Lekva T, Arora S, Otterdal K, Olsen MB, Kong XY, Gude E, Andreassen AK, Solbu D, Karason K, Dellgren G, Gullestad L, Aukrust P, Ueland T (2018)
Circulating delta-like Notch ligand 1 is correlated with cardiac allograft vasculopathy and suppressed in heart transplant recipients on everolimus-based immunosuppression
Am J Transplant, 19 (4), 1050-1060
DOI 10.1111/ajt.15141, PubMed 30312541

Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982

Nouri H, Monnier AF, Fossum-Raunehaug S, Maciag-Dorszynska M, Cabin-Flaman A, Képès F, Wegrzyn G, Szalewska-Palasz A, Norris V, Skarstad K, Janniere L (2018)
Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
DNA Res, 25 (6), 641-653
DOI 10.1093/dnares/dsy031, PubMed 30256918

Nymo SH, Hartford M, Ueland T, Yndestad A, Lorentzen E, Truvé K, Karlsson T, Ravn-Fischer A, Aukrust P, Caidahl K (2018)
Serum neutrophil gelatinase-associated lipocalin (NGAL) concentration is independently associated with mortality in patients with acute coronary syndrome
Int J Cardiol, 262, 79-84
DOI 10.1016/j.ijcard.2018.03.028, PubMed 29622507

Olsen AO (2018)
Human papillomavirus and immunosuppressive drugs in dermatology - a 'neoplastic' combination?
J Eur Acad Dermatol Venereol, 32 (2), 192
DOI 10.1111/jdv.14833, PubMed 29465832

Olson A, Bannert N, Sönnerborg A, de Mendoza C, Price M, Zangerle R, Chaix ML, Prins M, Kran AB, Gill J, Paraskevis D, Porter K, for CASCADE Collaboration in EuroCoord (2018)
Temporal trends of transmitted HIV drug resistance in a multinational seroconversion cohort
AIDS, 32 (2), 161-169
DOI 10.1097/QAD.0000000000001689, PubMed 29112061

Oma I, Olstad OK, Andersen JK, Lyberg T, Molberg Ø, Fostad I, Wang Fagerland M, Almdahl SM, Rynning SE, Yndestad A, Aukrust P, Whist JE, Hollan I (2018)
Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
PLoS One, 13 (8), e0202346
DOI 10.1371/journal.pone.0202346, PubMed 30138371

Orlien SMS, Ismael NY, Ahmed TA, Berhe N, Lauritzen T, Roald B, Goldin RD, Stene-Johansen K, Dyrhol-Riise AM, Gundersen SG, Morgan MY, Johannessen A (2018)
Unexplained chronic liver disease in Ethiopia: a cross-sectional study
BMC Gastroenterol, 18 (1), 27
DOI 10.1186/s12876-018-0755-5, PubMed 29439653

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279

Otterdal K, Berg A, Michelsen AE, Patel S, Tellevik MG, Haanshuus CG, Fevang B, Aukrust P, Langeland N, Ueland T (2018)
Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria
BMC Infect Dis, 18 (1), 670
DOI 10.1186/s12879-018-3593-8, PubMed 30563486

Pessia A, Corander J (2018)
Kpax3: Bayesian bi-clustering of large sequence datasets
Bioinformatics, 34 (12), 2132-2133
DOI 10.1093/bioinformatics/bty056, PubMed 29425273

Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
J Hepatol, 69 (2), 368-377
DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678

Puranen S, Pesonen M, Pensar J, Xu YY, Lees JA, Bentley SD, Croucher NJ, Corander J (2018)
SuperDCA for genome-wide epistasis analysis
Microb Genom, 4 (6)
DOI 10.1099/mgen.0.000184, PubMed 29813016

Quist-Paulsen E, Aukrust P, Kran AB, Dunlop O, Ormaasen V, Stiksrud B, Midttun Ø, Ueland T, Ueland PM, Mollnes TE, Dyrhol-Riise AM (2018)
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234

Reiseter S, Gunnarsson R, Mogens Aaløkken T, Lund MB, Mynarek G, Corander J, Haydon J, Molberg Ø (2018)
Progression and mortality of interstitial lung disease in mixed connective tissue disease: a long-term observational nationwide cohort study
Rheumatology (Oxford), 57 (2), 255-262
DOI 10.1093/rheumatology/kex077, PubMed 28379478

Reiten MR, Malachin G, Kommisrud E, Østby GC, Waterhouse KE, Krogenæs AK, Kusnierczyk A, Bjørås M, Jalland CMO, Nekså LH, Røed SS, Stenseth EB, Myromslien FD, Zeremichael TT, Bakkebø MK, Espenes A, Tranulis MA (2018)
Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein
Front Mol Biosci, 5, 1
DOI 10.3389/fmolb.2018.00001, PubMed 29417049

Richardson EJ, Bacigalupe R, Harrison EM, Weinert LA, Lycett S, Vrieling M, Robb K, Hoskisson PA, Holden MTG, Feil EJ, Paterson GK, Tong SYC, Shittu A, van Wamel W, Aanensen DM, Parkhill J, Peacock SJ, Corander J, Holmes M, Fitzgerald JR (2018)
Gene exchange drives the ecological success of a multi-host bacterial pathogen
Nat Ecol Evol, 2 (9), 1468-1478
DOI 10.1038/s41559-018-0617-0, PubMed 30038246

Rognlien AGW, Wollen EJ, Atneosen-Åsegg M, Suganthan R, Bjørås M, Saugstad OD (2018)
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
J Perinat Med, 47 (1), 114-124
DOI 10.1515/jpm-2018-0172, PubMed 30020889

Sane Schepisi M, Navarra A, Altet Gomez MN, Dudnyk A, Dyrhol-Riise AM, Esteban J, Giorgetti PF, Gualano G, Guglielmetti L, Heyckendorf J, Kaluzhenina A, Lange B, Lange C, Manika K, Miah J, Nanovic Z, Pontali E, Prego MR, Solovic I, Tiberi S, Palmieri F, Girardi E (2018)
Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study
Open Forum Infect Dis, 6 (1), ofy337
DOI 10.1093/ofid/ofy337, PubMed 30697572

Schein YL, Madebo T, Andersen HE, Arnesen TM, Dyrhol-Riise AM, Tveiten H, White RA, Winje BA (2018)
Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study
BMC Infect Dis, 18 (1), 587
DOI 10.1186/s12879-018-3468-z, PubMed 30453946

Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
J Intern Med, 284 (1), 78-91
DOI 10.1111/joim.12750, PubMed 29498764

Shekhar S, Khan R, Ferreira DM, Mitsi E, German E, Rørvik GH, Berild D, Schenck K, Kwon K, Petersen F (2018)
Antibodies Reactive to Commensal Streptococcus mitis Show Cross-Reactivity With Virulent Streptococcus pneumoniae Serotypes
Front Immunol, 9, 747
DOI 10.3389/fimmu.2018.00747, PubMed 29713324

Sikkeland LIB, Borander AK, Voie ØA, Aass HCD, Øvstebø R, Aukrust P, Longva K, Alexis NE, Kongerud J, Ueland T (2018)
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L (2018)
Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
Open Forum Infect Dis, 5 (2), ofy002
DOI 10.1093/ofid/ofy002, PubMed 29410975

Sipola A, Marttinen P, Corander J (2018)
Bacmeta: simulator for genomic evolution in bacterial metapopulations
Bioinformatics, 34 (13), 2308-2310
DOI 10.1093/bioinformatics/bty093, PubMed 29474733

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sørensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB (2018)
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254

Smet A, Yahara K, Rossi M, Tay A, Backert S, Armin E, Fox JG, Flahou B, Ducatelle R, Haesebrouck F, Corander J (2018)
Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence
ISME J, 12 (10), 2518-2531
DOI 10.1038/s41396-018-0199-5, PubMed 29942073

Sokolova M, Sahraoui A, Høyem M, Øgaard J, Lien E, Aukrust P, Yndestad A, Ranheim T, Scholz H (2018)
NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction
Am J Physiol Endocrinol Metab, 315 (5), E912-E923
DOI 10.1152/ajpendo.00461.2017, PubMed 30016155

Steineger J, Ueland T, Aukrust P, Michelsen A, Osnes T, Heimdal K, Dheyauldeen S (2018)
Pentraxin 3 level is elevated in hereditary hemorrhagic telangiectasia and reflects the severity of disease-associated epistaxis
Laryngoscope, 129 (1), E44-E49
DOI 10.1002/lary.27548, PubMed 30329172

Sørbye IK, Andersen HB, Melin E, Nordøy I (2018)
[A pregnant woman with headache and fever]
Tidsskr Nor Laegeforen, 138 (4)
DOI 10.4045/tidsskr.17.0383, PubMed 29460598

Tonkin-Hill G, Lees JA, Bentley SD, Frost SDW, Corander J (2018)
RhierBAPS: An R implementation of the population clustering algorithm hierBAPS
Wellcome Open Res, 3, 93
DOI 10.12688/wellcomeopenres.14694.1, PubMed 30345380

Top J, Sinnige JC, Brouwer EC, Werner G, Corander J, Severin JA, Jansen R, Bathoorn E, Bonten MJM, Rossen JWA, Willems RJL (2018)
Identification of a Novel Genomic Island Associated with vanD-Type Vancomycin Resistance in Six Dutch Vancomycin-Resistant Enterococcus faecium Isolates
Antimicrob Agents Chemother, 62 (3)
DOI 10.1128/AAC.01793-17, PubMed 29311068

Trevisan C, Sotiraki S, Laranjo-González M, Dermauw V, Wang Z, Kärssin A, Cvetkovikj A, Winkler AS, Abraham A, Bobić B, Lassen B, Cretu CM, Vasile C, Arvanitis D, Deksne G, Boro I, Kucsera I, Karamon J, Stefanovska J, Koudela B, Pavlova MJ, Varady M, Pavlak M, Šarkūnas M, Kaminski M et al. (2018)
Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe
Parasit Vectors, 11 (1), 569
DOI 10.1186/s13071-018-3153-5, PubMed 30376899

Tronstad RR, Polushina T, Brattbakk HR, Stansberg C, von Volkmann HL, Hanevik K, Ellinghaus E, Jørgensen SF, Ersland KM, Pham KD, Gilja OH, Hovdenak N, Hausken T, Vatn MH, Franke A, Knappskog PM, Le Hellard S, Karlsen TH, Fiskerstrand T (2018)
Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea
Scand J Gastroenterol, 53 (10-11), 1264-1273
DOI 10.1080/00365521.2018.1521867, PubMed 30353760

Troseid M, Nordoy I, Fevang B, Aukrust P (2018)
Tenders for HIV medicines are not academically justified
Tidsskr. Nor. Laegeforen., 138 (20), 1912-1913

Trøseid M, Nordøy I, Fevang B, Aukrust P (2018)
Tendering for HIV drugs is not clinically justified
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0808, PubMed 30539614

Traaen GM, Aakerøy L, Hunt TE, Øverland B, Lyseggen E, Aukrust P, Ueland T, Helle-Valle T, Steinshamn S, Edvardsen T, Khiabani Zaré H, Aakhus S, Akre H, Anfinsen OG, Loennechen JP, Gullestad L (2018)
Treatment of sleep apnea in patients with paroxysmal atrial fibrillation: design and rationale of a randomized controlled trial
Scand Cardiovasc J, 52 (6), 372-377
DOI 10.1080/14017431.2019.1567933, PubMed 30638392

Ueland T, Gullestad L, Kou L, Aukrust P, Anand IS, Broughton MN, McMurray JJ, van Veldhuisen DJ, Warren DJ, Bolstad N (2018)
Pro-gastrin-releasing peptide and outcome in patients with heart failure and anaemia: results from the RED-HF study
ESC Heart Fail, 5 (6), 1052-1059
DOI 10.1002/ehf2.12312, PubMed 30145817

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Aukrust P, Gullestad L, Halvorsen B, Yndestad A (2018)
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Open Heart, 5 (2), e000765
DOI 10.1136/openhrt-2017-000765, PubMed 30258647

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Holven KB, Aukrust P, Gullestad L, Yndestad A, Halvorsen B (2018)
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Int J Cardiol, 274, 348-350
DOI 10.1016/j.ijcard.2018.06.093, PubMed 29961573

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Aukrust P, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Wallentin L, PLATO (Platelet Inhibition and Patient Outcomes) Trial Investigators (2018)
Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.007009, PubMed 29330256

Vinkeles Melchers NVS, Mollenkopf S, Colebunders R, Edlinger M, Coffeng LE, Irani J, Zola T, Siewe JN, de Vlas SJ, Winkler AS, Stolk WA (2018)
Burden of onchocerciasis-associated epilepsy: first estimates and research priorities
Infect Dis Poverty, 7 (1), 101
DOI 10.1186/s40249-018-0481-9, PubMed 30253788

Wang N, Anonsen JH, Viburiene R, Lam JS, Vik Å, Koomey M (2018)
Disrupted Synthesis of a Di-N-acetylated Sugar Perturbs Mature Glycoform Structure and Microheterogeneity in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica
J Bacteriol, 201 (1)
DOI 10.1128/JB.00522-18, PubMed 30322851

Winje BA, White R, Syre H, Skutlaberg DH, Oftung F, Mengshoel AT, Blix HS, Brantsæter AB, Holter EK, Handal N, Simonsen GS, Afset JE, Bakken Kran AM (2018)
Stratification by interferon-γ release assay level predicts risk of incident TB
Thorax, 73 (7), 652-661
DOI 10.1136/thoraxjnl-2017-211147, PubMed 29622693

Winkler AS, Klohe K, Schmidt V, Haavardsson I, Abraham A, Prodjinotho UF, Ngowi B, Sikasunge C, Noormahomed E, Amuasi J, Kaducu J, Ngowi H, Abele-Ridder B, Harrison WE, Prazeres da Costa C (2018)
Neglected tropical diseases - the present and the future
Tidsskr Nor Laegeforen, 138 (3)
DOI 10.4045/tidsskr.17.0678, PubMed 29411594

Xu Y, Puranen S, Corander J, Kabashima Y (2018)
Inverse finite-size scaling for high-dimensional significance analysis
Phys Rev E, 97 (6-1), 062112
DOI 10.1103/PhysRevE.97.062112, PubMed 30011500

Zandi H, Kristoffersen AK, Ørstavik D, Rôças IN, Siqueira JF, Enersen M (2018)
Microbial Analysis of Endodontic Infections in Root-filled Teeth with Apical Periodontitis before and after Irrigation Using Pyrosequencing
J Endod, 44 (3), 372-378
DOI 10.1016/j.joen.2017.11.019, PubMed 29306533

Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, Online ahead of print (in press) (Retracted)
DOI 10.3324/haematol.2018.189399, PubMed 29748445

Zusinaite E, Ianevski A, Niukkanen D, Poranen MM, Bjørås M, Afset JE, Tenson T, Velagapudi V, Merits A, Kainov DE (2018)
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents
Viruses, 10 (8)
DOI 10.3390/v10080423, PubMed 30103549

Åberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Østensen A, Karlsen TH, Nordin A (2018)
Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
Liver Transpl, 24 (9), 1252-1259
DOI 10.1002/lt.25305, PubMed 30120902

Aas M, Dieset I, Mørch R, Steen NE, Hope S, Reponen EJ, Laskemoen JF, Ueland T, Aukrust P, Melle I, Agartz I, Andreassen OA (2018)
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813

Publications 2017

Abraityte A, Lunde IG, Askevold ET, Michelsen AE, Christensen G, Aukrust P, Yndestad A, Fiane A, Andreassen A, Aakhus S, Dahl CP, Gullestad L, Broch K, Ueland T (2017)
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
Gut, 67 (8), 1517-1524
DOI 10.1136/gutjnl-2016-313598, PubMed 28779025

Andam CP, Mitchell PK, Callendrello A, Chang Q, Corander J, Chaguza C, McGee L, Beall BW, Hanage WP (2017)
Genomic Epidemiology of Penicillin-Nonsusceptible Pneumococci with Nonvaccine Serotypes Causing Invasive Disease in the United States
J Clin Microbiol, 55 (4), 1104-1115
DOI 10.1128/JCM.02453-16, PubMed 28100596

Anonsen JH, Børud B, Vik Å, Viburiene R, Koomey M (2017)
Structural and genetic analyses of glycan O-acetylation in a bacterial protein glycosylation system: evidence for differential effects on glycan chain length
Glycobiology, 27 (9), 888-899
DOI 10.1093/glycob/cwx032, PubMed 28460017

Anumala UR, Waaler J, Nkizinkiko Y, Ignatev A, Lazarow K, Lindemann P, Olsen PA, Murthy S, Obaji E, Majouga AG, Leonov S, von Kries JP, Lehtiö L, Krauss S, Nazaré M (2017)
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568

Auensen A, Hussain AI, Falk RS, Walle-Hansen MM, Bye J, Pettersen KI, Aukrust P, Ueland T, Gullestad LL (2017)
Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis
PLoS One, 12 (6), e0179304
DOI 10.1371/journal.pone.0179304, PubMed 28604834

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T (2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312

Bakke V, Sporsem H, Von der Lippe E, Nordøy I, Lao Y, Nyrerød HC, Sandvik L, Hårvig KR, Bugge JF, Helset E (2017)
Vancomycin levels are frequently subtherapeutic in critically ill patients: a prospective observational study
Acta Anaesthesiol Scand, 61 (6), 627-635
DOI 10.1111/aas.12897, PubMed 28444760

Batmanov K, Wang W, Bjørås M, Delabie J, Wang J (2017)
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma
Sci Rep, 7 (1), 7040
DOI 10.1038/s41598-017-07226-4, PubMed 28765546

Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL (2017)
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371

Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
DOI 10.1152/ajpgi.00124.2017, PubMed 29212771

Beyene GT, Kalayou S, Riaz T, Tonjum T (2017)
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
BMC Microbiol, 17 (1), 96
DOI 10.1186/s12866-017-1004-8, PubMed 28431522

Birhanu AG, Yimer SA, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2017)
N_ε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated
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