Publications

Publications 2021

Arredondo-Alonso S, Top J, Corander J, Willems RJL, Schürch AC (2021)
Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals
Genome Med, 13 (1), 9
DOI 10.1186/s13073-020-00825-3, PubMed 33472670

Batisti Biffignandi G, Gibbon MJ, Corbella M, Thorpe HA, Merla C, Castelli M, Kallonen T, Pegrum K, Brisse S, Corander J, Marone P, Feil EJ, Sassera D (2021)
Genome of Superficieibacter maynardsmithii, a novel, antibiotic susceptible representative of Enterobacteriaceae
G3 (Bethesda), 11 (2)
DOI 10.1093/g3journal/jkab019, PubMed 33615377

Berg AK, Diseth TH, Abrahamsen TG, Halvorsen K, Reinfjell T, Erichsen HC (2021)
Primary antibody deficiency: The impact on the quality of life and mental health of affected children and their parents
Acta Paediatr
DOI 10.1111/apa.15752, PubMed 33420742

Binder K, Krauss S, Schmidmaier R, Braun LT (2021)
Natural frequency trees improve diagnostic efficiency in Bayesian reasoning
Adv Health Sci Educ Theory Pract (in press)
DOI 10.1007/s10459-020-10025-8, PubMed 33599875

Bjørkto MH, Barratt-Due A, Nordøy I, Dörje C, Galteland E, Lind A, Hilli A, Aukrust P, Mjøen G (2021)
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010

Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G et al. (2021)
Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations
Hum Mol Genet (in press)
DOI 10.1093/hmg/ddab017, PubMed 33555323

Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol
DOI 10.1080/00365521.2021.1880627, PubMed 33583308

Edvardsen MS, Hindberg K, Hansen ES, Morelli VM, Ueland T, Aukrust P, Brækkan SK, Evensen LH, Hansen JB (2021)
Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
Blood Adv, 5 (1), 224-232
DOI 10.1182/bloodadvances.2020003135, PubMed 33570640

Fraz MSA, Moe N, Revheim ME, Stavrinou ML, Durheim MT, Nordøy I, Macpherson ME, Aukrust P, Jørgensen SF, Aaløkken TM, Fevang B (2021)
Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency-Features of CT and ¹⁸F-FDG Positron Emission Tomography/CT in Clinically Progressive Disease
Front Immunol, 11, 617985
DOI 10.3389/fimmu.2020.617985, PubMed 33584710

Gibbon MJ, Couto N, David S, Barden R, Standerwick R, Jagadeesan K, Birkwood H, Dulyayangkul P, Avison MB, Kannan A, Kibbey D, Craft T, Habib S, Thorpe HA, Corander J, Kasprzyk-Hordern B, Feil EJ (2021)
A high prevalence of bla_OXA-48 in Klebsiella (Raoultella) ornithinolytica and related species in hospital wastewater in South West England
Microb Genom (in press)
DOI 10.1099/mgen.0.000509, PubMed 33416467

Harrow GL, Lees JA, Hanage WP, Lipsitch M, Corander J, Colijn C, Croucher NJ (2021)
Negative frequency-dependent selection and asymmetrical transformation stabilise multi-strain bacterial population structures
ISME J
DOI 10.1038/s41396-020-00867-w, PubMed 33408365

Helgesen E, Sætre F, Skarstad K (2021)
Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli
Sci Rep, 11 (1), 474
DOI 10.1038/s41598-020-80043-4, PubMed 33436807

Horesh G, Blackwell GA, Tonkin-Hill G, Corander J, Heinz E, Thomson NR (2021)
A comprehensive and high-quality collection of Escherichia coli genomes and their genes
Microb Genom (in press)
DOI 10.1099/mgen.0.000499, PubMed 33417534

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Ladner JT, Henson SN, Boyle AS, Engelbrektson AL, Fink ZW, Rahee F, D'ambrozio J, Schaecher KE, Stone M, Dong W, Dadwal S, Yu J, Caligiuri MA, Cieplak P, Bjørås M, Fenstad MH, Nordbø SA, Kainov DE, Muranaka N, Chee MS, Shiryaev SA, Altin JA (2021)
Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses
Cell Rep Med, 2 (1), 100189
DOI 10.1016/j.xcrm.2020.100189, PubMed 33495758

Mageiros L, Méric G, Bayliss SC, Pensar J, Pascoe B, Mourkas E, Calland JK, Yahara K, Murray S, Wilkinson TS, Williams LK, Hitchings MD, Porter J, Kemmett K, Feil EJ, Jolley KA, Williams NJ, Corander J, Sheppard SK (2021)
Genome evolution and the emergence of pathogenicity in avian Escherichia coli
Nat Commun, 12 (1), 765
DOI 10.1038/s41467-021-20988-w, PubMed 33536414

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B (2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
Nucleic Acids Res, 49 (3), 1470-1484
DOI 10.1093/nar/gkaa1289, PubMed 33444446

Skottvoll FS, Hansen FA, Harrison S, Boger IS, Mrsa A, Restan MS, Stein M, Lundanes E, Pedersen-Bjergaard S, Aizenshtadt A, Krauss S, Sullivan G, Bogen IL, Wilson SR (2021)
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551

Stelzle D, Storz C, Baxmann A, Liang LA, Burtscher C, Matuja W, Schmutzhard E, Winkler AS (2021)
Febrile seizures in an urban Tanzanian population: lessons learned from a community-based random cluster survey
Trop Med Int Health (in press)
DOI 10.1111/tmi.13548, PubMed 33415795

Ulvik IM, Sæthre T, Bunæs DF, Lie SA, Enersen M, Leknes KN (2021)
A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy
BMC Oral Health, 21 (1), 38
DOI 10.1186/s12903-021-01397-3, PubMed 33478480

Winkler AS, Leonardi M, Michael BD, Abd-Allah F, Carroll W, Guekht A, Global COVID-19 Neuro Research Coalition (2021)
A WHO resolution on epilepsy and other neurological disorders
Lancet Neurol, 20 (3), 171-172
DOI 10.1016/S1474-4422(21)00026-0, PubMed 33609470

Xu KQ, Chatzitakis A, Risbakk S, Yang MY, Backe PH, Grandcolas M, Bjoras M, Norby T (2021)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catal. Today, 361, 57-62

Zhang Y, Shen L, Dreissigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW (2021)
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease
Blood (in press)
DOI 10.1182/blood.2020008720, PubMed 33529322

Publications 2020

Aaløkken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Müller F, Schubert M, Jørgensen A, Blomberg SM, Bjørnerheim R, Kløw NE, Hopp E (2020)
Diagnostic imaging of COVID-19 patients
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0332, PubMed 32463192

Aalto-Araneda M, Pöntinen A, Pesonen M, Corander J, Markkula A, Tasara T, Stephan R, Korkeala H (2020)
Strain Variability of Listeria monocytogenes under NaCl Stress Elucidated by a High-Throughput Microbial Growth Data Assembly and Analysis Protocol
Appl Environ Microbiol, 86 (6)
DOI 10.1128/AEM.02378-19, PubMed 31900307

Aamodt AH, Flinstad Harbo H, Eldøen G, Barratt-Due A, Aukrust P (2020)
How does COVID-19 affect the brain?
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0444, PubMed 32602331

Abadpour S, Aizenshtadt A, Olsen PA, Shoji K, Wilson SR, Krauss S, Scholz H (2020)
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261

Abraham A, Schmidt V, Kaminski M, Stelzle D, De Meijere R, Bustos J, Sahu PS, Garcia HH, Bobić B, Cretu C, Chiodini P, Deksne G, Dermauw V, Devleesschauwer B, Dorny P, Fonseca A, Gabriël S, Gómez-Morales MA, Kucsera I, Laranjo-González M, Trevisan C, Vilhena M, Walker NF, Zammarchi L, Winkler AS (2020)
Epidemiology and surveillance of human (neuro)cysticercosis in Europe: is enhanced surveillance required?
Trop Med Int Health, 25 (5), 566-578
DOI 10.1111/tmi.13384, PubMed 32083787

Aimo A, Januzzi JL, Vergaro G, Richards AM, Lam CSP, Latini R, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, de Boer RA, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Gamble GD, Ling LH, Leong KTG, Yeo PSD et al. (2020)
Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T
Eur J Heart Fail, 22 (11), 2078-2088
DOI 10.1002/ejhf.1701, PubMed 31919929

Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548

Alfsnes K, Eldholm V, Olsen AO, Brynildsrud OB, Bohlin J, Steinbakk M, Caugant DA (2020)
Genomic epidemiology and population structure of Neisseria gonorrhoeae in Norway, 2016-2017
Microb Genom, 6 (4)
DOI 10.1099/mgen.0.000359, PubMed 32213251

Amuasi JH, Lucas T, Horton R, Winkler AS (2020)
Reconnecting for our future: The Lancet One Health Commission
Lancet, 395 (10235), 1469-1471
DOI 10.1016/S0140-6736(20)31027-8, PubMed 32386579

Amuasi JH, Walzer C, Heymann D, Carabin H, Huong LT, Haines A, Winkler AS (2020)
Calling for a COVID-19 One Health Research Coalition
Lancet, 395 (10236), 1543-1544
DOI 10.1016/S0140-6736(20)31028-X, PubMed 32386563

Amuasi JH, Winkler AS (2020)
One Health or Planetary Health for pandemic prevention? - Authors' reply
Lancet, 396 (10266), 1882-1883
DOI 10.1016/S0140-6736(20)32392-8, PubMed 33308466

Amundsen EK, Moholt TK, Meyer M, Haug JB, Berild D (2020)
Antibiotikastyring ved hjelp av prokalsitonin
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0056, PubMed 32815338

Andersen PI, Ianevski A, Lysvand H, Vitkauskiene A, Oksenych V, Bjørås M, Telling K, Lutsar I, Dumpis U, Irie Y, Tenson T, Kantele A, Kainov DE (2020)
Discovery and development of safe-in-man broad-spectrum antiviral agents
Int J Infect Dis, 93, 268-276
DOI 10.1016/j.ijid.2020.02.018, PubMed 32081774

Andersson DI, Balaban NQ, Baquero F, Courvalin P, Glaser P, Gophna U, Kishony R, Molin S, Tønjum T (2020)
Antibiotic resistance: turning evolutionary principles into clinical reality
FEMS Microbiol Rev, 44 (2), 171-188
DOI 10.1093/femsre/fuaa001, PubMed 31981358

Arain F, Abraityte A, Bogdanova M, Solberg OG, Michelsen AE, Lekva T, Aakhus S, Holm S, Halvorsen B, Finsen AV, Vinge LE, Nymo S, Espeland T, Ranheim T, Aukrust P, Vaage IJ, Auensen A, Gullestad L, Ueland T (2020)
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417

Arnold B, Sohail M, Wadsworth C, Corander J, Hanage WP, Sunyaev S, Grad YH (2020)
Fine-Scale Haplotype Structure Reveals Strong Signatures of Positive Selection in a Recombining Bacterial Pathogen
Mol Biol Evol, 37 (2), 417-428
DOI 10.1093/molbev/msz225, PubMed 31589312

Arredondo-Alonso S, Bootsma M, Hein Y, Rogers MRC, Corander J, Willems RJL, Schürch AC (2020)
gplas: a comprehensive tool for plasmid analysis using short-read graphs
Bioinformatics, 36 (12), 3874-3876
DOI 10.1093/bioinformatics/btaa233, PubMed 32271863

Aulokken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Muller F, Schubert M, Jorgensen A, Blomberg SM, Bjornerheim R, Klow NE, Hopp E (2020)
Imaging of patients with COVID-19
Tidsskr. Nor. Laegeforen., 140 (8), 756-760

Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WP (2020)
Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae
PLoS Biol, 18 (10), e3000878
DOI 10.1371/journal.pbio.3000878, PubMed 33091022

Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390

Berg A, Patel S, Tellevik MG, Haanshuus CG, Dalen I, Otterdal K, Ueland T, Moyo SJ, Aukrust P, Langeland N (2020)
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Infection, 48 (3), 367-373
DOI 10.1007/s15010-020-01399-3, PubMed 32077073

Berild D (2020)
Rettelse: Dårlig antibiotikabehandling, prisverdig åpenhet
Tidsskr Nor Laegeforen, 140 (15)
DOI 10.4045/tidsskr.20.0810, PubMed 33118764

Berild D (2020)
Poor antimicrobial therapy, commendable candour
Tidsskr Nor Laegeforen, 140 (14)
DOI 10.4045/tidsskr.20.0711, PubMed 33070592

Binder K, Krauss S, Wiesner P (2020)
A New Visualization for Probabilistic Situations Containing Two Binary Events: The Frequency Net
Front Psychol, 11, 750
DOI 10.3389/fpsyg.2020.00750, PubMed 32528335

Bjoras M (2020)
Nobel Prize for discovering how cells adapt to changing oxygen levels
Tidsskr. Nor. Laegeforen., 140 (1), 8

Booth JA, Špírek M, Lobie TA, Skarstad K, Krejci L, Bjørås M (2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Sci Rep, 10 (1), 19422
DOI 10.1038/s41598-020-76426-2, PubMed 33173044

Bruun T, Salamanca BV, Bekkevold T, Døllner H, Gibory M, Gilje AM, Haarr E, Kran AB, Leegaard TM, Nakstad B, Nordbø SA, Rojahn A, Størdal K, Flem E, Norwegian Enhanced Pediatric Immunisation Surveillance (NorEPIS) Network (2020)
Impact of the Rotavirus Vaccination Program in Norway After Four Years With High Coverage
Pediatr Infect Dis J, Publish Ahead of Print (in press)
DOI 10.1097/INF.0000000000003020, PubMed 33399430

Christensen I, Haug JB, Berild D, Bjørnholt JV, Jelsness-Jørgensen LP (2020)
Hospital physicians' experiences with procalcitonin - implications for antimicrobial stewardship; a qualitative study
BMC Infect Dis, 20 (1), 515
DOI 10.1186/s12879-020-05246-6, PubMed 32677903

Colijn C, Corander J, Croucher NJ (2020)
Designing ecologically optimized pneumococcal vaccines using population genomics
Nat Microbiol, 5 (3), 473-485
DOI 10.1038/s41564-019-0651-y, PubMed 32015499

Deeb M, Karlsen TH, Hirschfield GM (2020)
The 6 C's of primary sclerosing cholangitis
J Hepatol, 73 (5), 1255-1256
DOI 10.1016/j.jhep.2020.06.033, PubMed 32649970

Derer S, Brethack AK, Pietsch C, Jendrek ST, Nitzsche T, Bokemeyer A, Hov JR, Schäffler H, Bettenworth D, Grassl GA, Sina C (2020)
Inflammatory Bowel Disease-associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria
Inflamm Bowel Dis, 26 (12), 1856-1868
DOI 10.1093/ibd/izaa069, PubMed 32304568

Dobrovolska O, Brilkov M, Madeleine N, Ødegård-Fougner Ø, Strømland Ø, Martin SR, De Marco V, Christodoulou E, Teigen K, Isaksson J, Underhaug J, Reuter N, Aalen RB, Aasland R, Halskau Ø (2020)
The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection
FEBS J, 287 (20), 4458-4480
DOI 10.1111/febs.15256, PubMed 32083791

Dorst J, Schuster J, Dreyhaupt J, Witzel S, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grehl T, Hermann A, Jordan B, Grosskreutz J, Zeller D, Boentert M, Schrank B, Prudlo J, Winkler AS, Gorbulev S, Roselli F, Dupuis L, Otto M, Ludolph AC (2020)
Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis
J Neurol Neurosurg Psychiatry, 91 (9), 1007-1009
DOI 10.1136/jnnp-2020-323372, PubMed 32788256

Farooq A, Grønmyr S, Ali O, Rognes T, Scheffler K, Bjørås M, Wang J (2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data
Comput Struct Biotechnol J, 18, 2877-2889
DOI 10.1016/j.csbj.2020.09.038, PubMed 33163148

Fitak RR, Mohandesan E, Corander J, Yadamsuren A, Chuluunbat B, Abdelhadi O, Raziq A, Nagy P, Walzer C, Faye B, Burger PA (2020)
Genomic signatures of domestication in Old World camels
Commun Biol, 3 (1), 316
DOI 10.1038/s42003-020-1039-5, PubMed 32561887

Floeystad HK, Berild JD, Brandsaeter BJ, Vestrheim DF, Berild D, Holm AM (2020)
Gastrointestinal symptoms in invasive pneumococcal disease: a cohort study
BMC Infect Dis, 20 (1), 479
DOI 10.1186/s12879-020-05211-3, PubMed 32631331

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Gelpi M, Ueland PM, Trøseid M, Mocroft A, Lebech AM, Ullum H, Midttun Ø, Lundgren J, Nielsen SD (2020)
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus
J Infect Dis, 221 (3), 419-427
DOI 10.1093/infdis/jiz465, PubMed 31538186

Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
Clin Infect Dis, 71 (8), e359-e367
DOI 10.1093/cid/ciz1235, PubMed 31894240

George MJ, Kleveland O, Garcia-Hernandez J, Palmen J, Lovering R, Wiseth R, Aukrust P, Engmann J, Damås JK, Hingorani AD, Gullestad L, Casas JP, Ueland T (2020)
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform
J Am Heart Assoc, 9 (12), e015628
DOI 10.1161/JAHA.119.015628, PubMed 32515246

Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities
Hepatology, 72 (4), 1253-1266
DOI 10.1002/hep.31110, PubMed 31925805

Gregersen I, Michelsen AE, Lunde NN, Åkerblom A, Lakic TG, Skjelland M, Ryeng Skagen K, Becker RC, Lindbäck J, Himmelmann A, Solberg R, Johansen HT, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Ueland T, Wallentin L, Halvorsen B (2020)
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 9 (17), e016360
DOI 10.1161/JAHA.120.016360, PubMed 32809893

Grinde D, Øverland T, Lima K, Schjalm C, Mollnes TE, Abrahamsen TG (2020)
Complement Activation in 22q11.2 Deletion Syndrome
J Clin Immunol, 40 (3), 515-523
DOI 10.1007/s10875-020-00766-x, PubMed 32152940

Gruetzmacher K, Karesh WB, Amuasi JH, Arshad A, Farlow A, Gabrysch S, Jetzkowitz J, Lieberman S, Palmer C, Winkler AS, Walzer C (2020)
The Berlin principles on one health - Bridging global health and conservation
Sci Total Environ, 764, 142919
DOI 10.1016/j.scitotenv.2020.142919, PubMed 33097250

Gul KA, Strand J, Pettersen RD, Brun H, Abrahamsen TG (2020)
T-cell Receptor Excision Circles in Newborns with Heart Defects
Pediatr Cardiol, 41 (4), 809-815
DOI 10.1007/s00246-020-02317-y, PubMed 32166410

Haagsma JA, James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, Lucchesi LR, Roberts NLS, Sylte DO, Adebayo OM, Ahmadi A, Ahmed MB, Aichour MTE, Alahdab F, Alghnam SA, Aljunid SM, Al-Raddadi RM, Alsharif U, Altirkawi K, Anjomshoa M, Antonio CAT, Appiah SCY, Aremu O, Arora A et al. (2020)
Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017
Inj Prev, 26 (Supp 1), i12-i26
DOI 10.1136/injuryprev-2019-043296, PubMed 31915273

Hamamoto Filho PT, Singh G, Winkler AS, Carpio A, Fleury A (2020)
Could Differences in Infection Pressure Be Involved in Cysticercosis Heterogeneity?
Trends Parasitol, 36 (10), 826-834
DOI 10.1016/j.pt.2020.07.003, PubMed 32819826

Hansen ES, Hindberg K, Latysheva N, Aukrust P, Ueland T, Hansen JB, Brækkan SK, Morelli VM, INVENT Consortium (2020)
Plasma levels of growth differentiation factor 15 are associated with future risk of venous thromboembolism
Blood, 136 (16), 1863-1870
DOI 10.1182/blood.2019004572, PubMed 32645137

Helset E, Nordøy I, Sporsem H, Bakke VD, Bugge JF, Gammelsrud KW, Zucknick M, von der Lippe E (2020)
Factors increasing the risk of inappropriate vancomycin therapy in ICU patients: A prospective observational study
Acta Anaesthesiol Scand, 64 (9), 1295-1304
DOI 10.1111/aas.13658, PubMed 32578201

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Front Psychiatry, 11, 672
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Rodriguez-Vargas JM, Martin-Hernandez K, Wang W, Kunath N, Suganthan R, Amé JC, Oliver FJ, Ye J, Bjørås M, Dantzer F (2020)
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
Cell Death Dis, 11 (11), 954
DOI 10.1038/s41419-020-03167-5, PubMed 33159039

Rojahn AE, Gammelsrud KW, Brunvand LI, Hanche-Olsen TP, Schistad O, Sæter CB, Haaland K (2020)
Rettelse: Multiorgan inflammatorisk syndrom assosiert med sars-CoV-2 hos et barn
Tidsskr Nor Laegeforen, 140
DOI 10.4045/tidsskr.20.0576, PubMed 32815359

Rojahn AE, Gammelsrud KW, Brunvand LI, Hanche-Olsen TP, Schistad O, Sæter CB, Haaland K (2020)
Multiorgan inflammatory syndrome associated with SARS-CoV-2 in a child
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0485, PubMed 32815352

Sahaf Naeini A, Farooq A, Bjørås M, Wang J (2020)
IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity
Comput Struct Biotechnol J, 18, 1270-1286
DOI 10.1016/j.csbj.2020.05.024, PubMed 32612751

Scheffler K, Jalland CMO, Benestad SL, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis MA (2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Free Radic Biol Med, 152, 348-354
DOI 10.1016/j.freeradbiomed.2020.03.030, PubMed 32259578

Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
N Engl J Med, 383 (16), 1522-1534
DOI 10.1056/NEJMoa2020283, PubMed 32558485

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Sikkeland LI, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2020)
Lung CD4+ T cells in patients with lung fibrosis produce pro-fibrotic IL-13 together with IFNγ
Eur Respir J (in press)
DOI 10.1183/13993003.00983-2020, PubMed 33154027

Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482

Stelzle D, Tanaka LF, Lee KK, Ibrahim Khalil A, Baussano I, Shah ASV, McAllister DA, Gottlieb SL, Klug SJ, Winkler AS, Bray F, Baggaley R, Clifford GM, Broutet N, Dalal S (2020)
Estimates of the global burden of cervical cancer associated with HIV
Lancet Glob Health, 9 (2), e161-e169
DOI 10.1016/S2214-109X(20)30459-9, PubMed 33212031

Strand J, Gul KA, Erichsen HC, Lundman E, Berge MC, Trømborg AK, Sørgjerd LK, Ytre-Arne M, Hogner S, Halsne R, Gaup HJ, Osnes LT, Kro GAB, Sorte HS, Mørkrid L, Rowe AD, Tangeraas T, Jørgensen JV, Alme C, Bjørndalen TEH, Rønnestad AE, Lang AM, Rootwelt T, Buechner J, Øverland T et al. (2020)
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152

Szabo A, Akkouh IA, Ueland T, Lagerberg TV, Dieset I, Bjella T, Aukrust P, Le Hellard S, Stavrum AK, Melle I, Andreassen OA, Djurovic S (2020)
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224

Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnova M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Floisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem (in press)
DOI 10.1074/jbc.RA120.015285, PubMed 33303632

Taxt AM, Grødeland G, Lind A, Müller F (2020)
Status of COVID-19 vaccine development
Tidsskr Nor Laegeforen, 140 (13)
DOI 10.4045/tidsskr.20.0676, PubMed 32998488

Thaulow CM, Lindemann PC, Klingenberg C, Berild D, Salvesen Blix H, Myklebust TÅ, Harthug S (2020)
Epidemiology and Antimicrobial Susceptibility of Invasive Bacterial Infections in Children-A Population-Based Study From Norway
Pediatr Infect Dis J, Publish Ahead of Print (in press)
DOI 10.1097/INF.0000000000003013, PubMed 33298760

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Nature, 583 (7814), 90-95
DOI 10.1038/s41586-020-2265-1, PubMed 32499645

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Nature, 584 (7819), E2
DOI 10.1038/s41586-020-2556-6, PubMed 32678341

Tholin B, Hauge MT, Aukrust P, Fehrle L, Tvedt TH (2020)
Hemophagocytic lymphohistiocytosis in a patient with COVID-19 treated with tocilizumab: a case report
J Med Case Rep, 14 (1), 187
DOI 10.1186/s13256-020-02503-9, PubMed 33054818

Thudium RF, Knudsen AD, Stemann JHV, Hove-Skovsgaard M, Hoel H, Mocroft A, Reekie J, Ronit A, Gerstoft J, Vestbo J, Trøseid M, Borges ÁH, Ostrowski SR, Nielsen SD (2020)
Independent Association of Interleukin 6 With Low Dynamic Lung Function and Airflow Limitation in Well-Treated People With Human Immunodeficiency Virus
J Infect Dis (in press)
DOI 10.1093/infdis/jiaa600, PubMed 33141877

Tollånes MC, Bakken Kran AM, Abildsnes E, Jenum PA, Breivik AC, Sandberg S (2020)
Evaluation of eleven rapid tests for detection of antibodies against SARS-CoV-2
Clin Chem Lab Med, 58 (9), 1595-1600
DOI 10.1515/cclm-2020-0628, PubMed 32598303

Tonkin-Hill G, MacAlasdair N, Ruis C, Weimann A, Horesh G, Lees JA, Gladstone RA, Lo S, Beaudoin C, Floto RA, Frost SDW, Corander J, Bentley SD, Parkhill J (2020)
Producing polished prokaryotic pangenomes with the Panaroo pipeline
Genome Biol, 21 (1), 180
DOI 10.1186/s13059-020-02090-4, PubMed 32698896

Top J, Arredondo-Alonso S, Schürch AC, Puranen S, Pesonen M, Pensar J, Willems RJL, Corander J (2020)
Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen, Enterococcus faecium
Microb Genom, 6 (12)
DOI 10.1099/mgen.0.000488, PubMed 33253085

Trøseid M (2020)
When COVID-19 meets the African health service
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0283, PubMed 32378852

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Trøseid M, Lutro O, Ormaasen V (2020)
Experimental treatment for COVID-19 should be undertaken in randomised studies
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0282, PubMed 32378863

Tveiten H, Aukrust P, Lehne G, Rodriguez JR, Skjønsberg OH (2020)
Haemophagocytic lymphohistiocytosis in COVID-19 cases?
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.20.0240, PubMed 32321221

Tveiten H, Lehne G, Aukrust P, Rodriguez JR, Skjønsberg OH (2020)
A man in his forties with increasing shortness of breath
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.19.0692, PubMed 32321231

Ueland T, Estensen ME, Grindheim G, Bollerslev J, Henriksen T, Aukrust P, Aakhus S, Gullestad L, Lekva T (2020)
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Ueland T, Holter JC, Holten AR, Müller KE, Lind A, Bekken GK, Dudman S, Aukrust P, Dyrhol-Riise AM, Heggelund L (2020)
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675

Ueland T, Roland MCP, Michelsen AE, Godang K, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2020)
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383

Ulvestad E, Kommedal Ø, Simonsen GS, Müller F, Leegaard TM, Löhr IH, Nordbø SA (2020)
Norges mikrobiologiske utbruddsberedskap er truet
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0451, PubMed 32815358

Valestrand L, Berntsen NL, Zheng F, Schrumpf E, Hansen SH, Karlsen TH, Blumberg RS, Hov JR, Jiang X, Melum E (2020)
Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
Clin Exp Immunol, 203 (2), 304-314
DOI 10.1111/cei.13541, PubMed 33089489

Vesterhus M, Karlsen TH (2020)
Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
J Gastroenterol, 55 (6), 588-614
DOI 10.1007/s00535-020-01681-z, PubMed 32222826

Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2020)
Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
JHEP Rep, 3 (1), 100178
DOI 10.1016/j.jhepr.2020.100178, PubMed 33225252

Waaler J, Leenders RGG, Sowa ST, Alam Brinch S, Lycke M, Nieczypor P, Aertssen S, Murthy S, Galera-Prat A, Damen E, Wegert A, Nazaré M, Lehtiö L, Krauss S (2020)
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
J Med Chem, 63 (13), 6834-6846
DOI 10.1021/acs.jmedchem.0c00208, PubMed 32511917

Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858

Wang H, Kuusela S, Rinnankoski-Tuikka R, Dumont V, Bouslama R, Ramadan UA, Waaler J, Linden AM, Chi NW, Krauss S, Pirinen E, Lehtonen S (2020)
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Int J Obes (Lond), 44 (8), 1691-1702
DOI 10.1038/s41366-020-0573-z, PubMed 32317752

Wang N, Anonsen JH, Hadjineophytou C, Reinar WB, Børud B, Vik Å, Koomey M (2020)
Allelic polymorphisms in a glycosyltransferase gene shape glycan repertoire in the O-linked protein glycosylation system of Neisseria
Glycobiology (in press)
DOI 10.1093/glycob/cwaa073, PubMed 32776107

Watila MM, Balarabe SA, Komolafe M, Igwe SC, Bimbo Fawale M, van Diessen E, Nyandaiti YW, Singh G, Winkler AS, Sander JW (2020)
Translation and validation of an epilepsy-screening questionnaire in three Nigerian languages
Epilepsy Behav, 114 (Pt A), 107604
DOI 10.1016/j.yebeh.2020.107604, PubMed 33268016

Wedervang-Resell K, Ueland T, Aukrust P, Friis S, Holven KB, H Johannessen C, Lekva T, Lonning V, Smelror RE, Szabo A, Andreassen OA, Myhre AM, Agartz I (2020)
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840

Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Agdestein A, Tessema GT, Tønjum T, Yimer SA (2020)
Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
PLoS One, 15 (8), e0236362
DOI 10.1371/journal.pone.0236362, PubMed 32797053

Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Tønjum T, Yimer SA (2020)
Frequency and patterns of first- and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in a cross-sectional study in Tigray Region, Ethiopia
J Glob Antimicrob Resist, 24, 6-13 (in press)
DOI 10.1016/j.jgar.2020.11.017, PubMed 33279682

WHO Solidarity Trial Consortium, Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Abdool Karim Q, Alejandria MM, Hernández García C, Kieny MP, Malekzadeh R, Murthy S, Reddy KS, Roses Periago M, Abi Hanna P, Ader F, Al-Bader AM, Alhasawi A, Allum E, Alotaibi A, Alvarez-Moreno CA, Appadoo S, Asiri A, Aukrust P, Barratt-Due A et al. (2020)
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556

Winkler AS, Knauss S, Schmutzhard E, Leonardi M, Padovani A, Abd-Allah F, Charway-Felli A, Emmrich JV, Umapathi T, Satishchandra P, Hoo FK, Dalmau J, Oreja-Guevara C, Ferreira MLB, Pfausler B, Michael BD, Tagliavini F, Höglinger G, Endres M, Klein C, Hemmer B, Carroll W, Sejvar J, Solomon T (2020)
A call for a global COVID-19 Neuro Research Coalition
Lancet Neurol, 19 (6), 482-484
DOI 10.1016/S1474-4422(20)30150-2, PubMed 32470416

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

Yaqub S, Rana MU, Aukrust P (2020)
Ramadan under covid-19-pandemien
Tidsskr Nor Laegeforen, 140
DOI 10.4045/tidsskr.20.0390, PubMed 32378869

Yimer SA, Kalayou S, Homberset H, Birhanu AG, Riaz T, Zegeye ED, Lutter T, Abebe M, Holm-Hansen C, Aseffa A, Tønjum T (2020)
Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
Front Microbiol, 11, 550760
DOI 10.3389/fmicb.2020.550760, PubMed 33072011

Publications 2019

Abrahamsen TG (2019)
Helping on call paediatricians to identify acute primary immunodeficiency diseases
Acta Paediatr, 108 (12), 2127-2128
DOI 10.1111/apa.15000, PubMed 31621102

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2019)
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 10 (1), 1991
DOI 10.1038/s41467-019-10070-x, PubMed 31024006

Ahmadi A, Till K, Hafting Y, Schüttpelz M, Bjørås M, Glette K, Tørresen J, Rowe AD, Dalhus B (2019)
Additive manufacturing of laminar flow cells for single-molecule experiments
Sci Rep, 9 (1), 16784
DOI 10.1038/s41598-019-53151-z, PubMed 31727950

Andersen PI, Krpina K, Ianevski A, Shtaida N, Jo E, Yang J, Koit S, Tenson T, Hukkanen V, Anthonsen MW, Bjoras M, Evander M, Windisch MP, Zusinaite E, Kainov DE (2019)
Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine
Viruses, 11 (10)
DOI 10.3390/v11100964, PubMed 31635418

Andersen T, Ueland T, Ghukasyan Lakic T, Åkerblom A, Bertilsson M, Aukrust P, Michelsen AE, James SK, Becker RC, Storey RF, Wallentin L, Siegbahn A, Kontny F (2019)
C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (11), 2402-2410
DOI 10.1161/ATVBAHA.119.312633, PubMed 31554419

Anstensrud AK, Woxholt S, Sharma K, Broch K, Bendz B, Aakhus S, Ueland T, Amundsen BH, Damås JK, Hopp E, Kleveland O, Stensæth KH, Opdahl A, Kløw NE, Seljeflot I, Andersen GØ, Wiseth R, Aukrust P, Gullestad L (2019)
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391

Arredondo-Alonso S, Rogers MRC, Braat JC, Verschuuren TD, Top J, Corander J, Willems RJL, Schürch AC (2019)
Corrigendum: mlplasmids: a user-friendly tool to predict plasmid- and chromosome-derived sequences for single species
Microb Genom, 5 (1)
DOI 10.1099/mgen.0.000249, PubMed 30714567

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2019)
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620

Berdal JE, Follin-Arbelet B, Bjørnholt JV (2019)
Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter
BMC Infect Dis, 19 (1), 630
DOI 10.1186/s12879-019-4271-1, PubMed 31315581

Berges N, Nawaz MS, Børresdatter Dahl T, Hagen L, Bjørås M, Laerdahl JK, Alseth I (2019)
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
PLoS One, 14 (11), e0225081
DOI 10.1371/journal.pone.0225081, PubMed 31703097

Berry JL, Gurung I, Anonsen JH, Spielman I, Harper E, Hall AMJ, Goosens VJ, Raynaud C, Koomey M, Biais N, Matthews S, Pelicic V (2019)
Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis
J Biol Chem, 294 (17), 6796-6808
DOI 10.1074/jbc.RA118.006917, PubMed 30837269

Birhanu AG, Yimer SA, Kalayou S, Riaz T, Zegeye ED, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2019)
Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Sci Rep, 9 (1), 2927
DOI 10.1038/s41598-019-39654-9, PubMed 30814666

Bjørås M (2019)
Nobel Prize for discovery of how cells adapt to changing oxygen level
Tidsskr Nor Laegeforen, 139 (1)
DOI 10.4045/tidsskr.19.0764, PubMed 31948215

Bösl K, Ianevski A, Than TT, Andersen PI, Kuivanen S, Teppor M, Zusinaite E, Dumpis U, Vitkauskiene A, Cox RJ, Kallio-Kokko H, Bergqvist A, Tenson T, Merits A, Oksenych V, Bjørås M, Anthonsen MW, Shum D, Kaarbø M, Vapalahti O, Windisch MP, Superti-Furga G, Snijder B, Kainov D, Kandasamy RK (2019)
Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis
Front Immunol, 10, 2186
DOI 10.3389/fimmu.2019.02186, PubMed 31636628

Bottieau E, Mukendi D, Kalo JL, Lutumba P, Barbé B, Ramadan K, Van Esbroeck M, Jacobs J, Yansouni CP, Chappuis F, Boelaert M, Winkler AS, Verdonck K (2019)
Potential usefulness of C-reactive protein and procalcitonin determination in patients admitted for neurological disorders in rural Democratic Republic of Congo
Sci Rep, 9 (1), 15505
DOI 10.1038/s41598-019-51925-z, PubMed 31664120

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481

Bruckmaier G, Binder K, Krauss S, Kufner HM (2019)
An Eye-Tracking Study of Statistical Reasoning With Tree Diagrams and 2 × 2 Tables
Front Psychol, 10, 632
DOI 10.3389/fpsyg.2019.00632, PubMed 31156488

Brumpton BM, Fritsche LG, Zheng J, Nielsen JB, Mannila M, Surakka I, Rasheed H, Vie GÅ, Graham SE, Gabrielsen ME, Laugsand LE, Aukrust P, Vatten LJ, Damås JK, Ueland T, Janszky I, Zwart JA, Van't Hooft FM, Seidah NG, Hveem K, Willer C, Smith GD, Åsvold BO, INVENT Consortium (2019)
Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition
Circ Genom Precis Med, 12 (1), e002335
DOI 10.1161/CIRCGEN.118.002335, PubMed 30645169

Caidahl K, Hartford M, Ravn-Fischer A, Lorentzen E, Yndestad A, Karlsson T, Aukrust P, Ueland T (2019)
Homeostatic Chemokines and Prognosis in Patients With Acute Coronary Syndromes
J Am Coll Cardiol, 74 (6), 774-782
DOI 10.1016/j.jacc.2019.06.030, PubMed 31395128

Carpino G, Cardinale V, Folseraas T, Overi D, Grzyb K, Costantini D, Berloco PB, Di Matteo S, Karlsen TH, Alvaro D, Gaudio E (2019)
Neoplastic Transformation of the Peribiliary Stem Cell Niche in Cholangiocarcinoma Arisen in Primary Sclerosing Cholangitis
Hepatology, 69 (2), 622-638
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Quist-Paulsen E, Kran AB, Lindland ES, Ellefsen K, Sandvik L, Dunlop O, Ormaasen V (2019)
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985

Quist-Paulsen E, Ormaasen V, Kran AB, Dunlop O, Ueland PM, Ueland T, Eikeland R, Aukrust P, Nordenmark TH (2019)
Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning
Sci Rep, 9 (1), 16158
DOI 10.1038/s41598-019-52570-2, PubMed 31695095

Roaldsnes E, Eikeland R, Berild D (2019)
Lyme borreliosis and antibiotic therapy
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0222, PubMed 30969057

Roaldsnes E, Eikeland R, Berild D (2019)
Lyme disease and antibiotic treatment
Tidsskr. Nor. Laegeforen., 139 (7), 586

Rørslett Hardersen L, Enersen M, Kristoffersen AK, Ørstavik D, Sunde PT (2019)
Maintenance of the aseptic working field during endodontic treatment
Acta Odontol Scand, 77 (7), 502-507
DOI 10.1080/00016357.2019.1606935, PubMed 31094270

Rühlemann MC, Solovjeva MEL, Zenouzi R, Liwinski T, Kummen M, Lieb W, Hov JR, Schramm C, Franke A, Bang C (2019)
Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
Gut, 69 (10), 1890-1892
DOI 10.1136/gutjnl-2019-320008, PubMed 31653787

Rusthen S, Kristoffersen AK, Young A, Galtung HK, Petrovski BÉ, Palm Ø, Enersen M, Jensen JL (2019)
Dysbiotic salivary microbiota in dry mouth and primary Sjögren's syndrome patients
PLoS One, 14 (6), e0218319
DOI 10.1371/journal.pone.0218319, PubMed 31211815

Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
Eur J Clin Invest, 49 (5), e13088
DOI 10.1111/eci.13088, PubMed 30762236

Sánchez-Busó L, Golparian D, Corander J, Grad YH, Ohnishi M, Flemming R, Parkhill J, Bentley SD, Unemo M, Harris SR (2019)
The impact of antimicrobials on gonococcal evolution
Nat Microbiol, 4 (11), 1941-1950
DOI 10.1038/s41564-019-0501-y, PubMed 31358980

Schaufler K, Semmler T, Wieler LH, Trott DJ, Pitout J, Peirano G, Bonnedahl J, Dolejska M, Literak I, Fuchs S, Ahmed N, Grobbel M, Torres C, McNally A, Pickard D, Ewers C, Croucher NJ, Corander J, Guenther S (2019)
Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.00243-19, PubMed 30885899

Scheffler K, Bjørås KØ, Bjørås M (2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain
DNA Repair (Amst), 81, 102665
DOI 10.1016/j.dnarep.2019.102665, PubMed 31327582

Schmidt V, O'Hara MC, Ngowi B, Herbinger KH, Noh J, Wilkins PP, Richter V, Kositz C, Matuja W, Winkler AS (2019)
Taenia solium cysticercosis and taeniasis in urban settings: Epidemiological evidence from a health-center based study among people with epilepsy in Dar es Salaam, Tanzania
PLoS Negl Trop Dis, 13 (12), e0007751
DOI 10.1371/journal.pntd.0007751, PubMed 31809501

Schneditz G, Elias JE, Pagano E, Zaeem Cader M, Saveljeva S, Long K, Mukhopadhyay S, Arasteh M, Lawley TD, Dougan G, Bassett A, Karlsen TH, Kaser A, Kaneider NC (2019)
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
Sci Signal, 12 (562)
DOI 10.1126/scisignal.aau9048, PubMed 30600262

Shahini N, Ueland T, Auensen A, Michelsen AE, Ludviksen JK, Hussain AI, Pettersen KI, Aakhus S, Espeland T, Lunde IG, Kirschfink M, Nilsson PH, Mollnes TE, Gullestad L, Aukrust P, Yndestad A, Louwe MC (2019)
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744

Shi W, Cui P, Niu H, Zhang S, Tønjum T, Zhu B, Zhang Y (2019)
Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.02681-18, PubMed 30858213

Siljan WW, Holter JC, Michelsen AE, Nymo SH, Lauritzen T, Oppen K, Husebye E, Ueland T, Mollnes TE, Aukrust P, Heggelund L (2019)
Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study
ERJ Open Res, 5 (1)
DOI 10.1183/23120541.00014-2019, PubMed 30863773

Smet A, Yahara K, Rossi M, Tay A, Backert S, Ensser A, Fox JG, Flahou B, Ducatelle R, Haesebrouck F, Corander J (2019)
Correction: Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence
ISME J, 13 (7), 1890
DOI 10.1038/s41396-019-0380-5, PubMed 30820036

Sokolova M, Ranheim T, Louwe MC, Halvorsen B, Yndestad A, Aukrust P (2019)
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530

Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang L, Haugstad SB, Bendiksen BA, Øgaard J, Bliksøen M, Lien E, Berge RK, Aukrust P, Ranheim T, Yndestad A (2019)
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
Front Immunol, 10, 1621
DOI 10.3389/fimmu.2019.01621, PubMed 31379826

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Solberg OG, Stavem K, Ragnarsson A, Beitnes JO, Skårdal R, Seljeflot I, Ueland T, Aukrust P, Gullestad L, Aaberge L (2019)
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv, 94 (5), 660-668
DOI 10.1002/ccd.28157, PubMed 30790446

Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356

Storm-Larsen C, Myhr KM, Farbu E, Midgard R, Nyquist K, Broch L, Berg-Hansen P, Buness A, Holm K, Ueland T, Fallang LE, Burum-Auensen E, Hov JR, Holmøy T (2019)
Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
DOI 10.1177/2055217319888767, PubMed 31798939

Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315

Thaulow CM, Berild D, Blix HS, Brigtsen AK, Myklebust TÅ, Eriksen BH (2019)
Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital
Front Pediatr, 7, 440
DOI 10.3389/fped.2019.00440, PubMed 31709209

Thaulow CM, Berild D, Eriksen BH, Myklebust TÅ, Blix HS (2019)
Potential for More Rational Use of Antibiotics in Hospitalized Children in a Country With Low Resistance: Data From eight Point Prevalence Surveys
Pediatr Infect Dis J, 38 (4), 384-389
DOI 10.1097/INF.0000000000002106, PubMed 30882728

Thaulow CM, Blix HS, Eriksen BH, Ask I, Myklebust TÅ, Berild D (2019)
Using a period incidence survey to compare antibiotic use in children between a university hospital and a district hospital in a country with low antimicrobial resistance: a prospective observational study
BMJ Open, 9 (5), e027836
DOI 10.1136/bmjopen-2018-027836, PubMed 31138583

Thingholm LB, Rühlemann MC, Koch M, Fuqua B, Laucke G, Boehm R, Bang C, Franzosa EA, Hübenthal M, Rahnavard A, Frost F, Lloyd-Price J, Schirmer M, Lusis AJ, Vulpe CD, Lerch MM, Homuth G, Kacprowski T, Schmidt CO, Nöthlings U, Karlsen TH, Lieb W, Laudes M, Franke A, Huttenhower C (2019)
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
Cell Host Microbe, 26 (2), 252-264.e10
DOI 10.1016/j.chom.2019.07.004, PubMed 31399369

Thurn T, Borasio GD, Chiò A, Galvin M, McDermott CJ, Mora G, Sermeus W, Winkler AS, Anneser J (2019)
Physicians' attitudes toward end-of-life decisions in amyotrophic lateral sclerosis
Amyotroph Lateral Scler Frontotemporal Degener, 20 (1-2), 74-81
DOI 10.1080/21678421.2018.1536154, PubMed 30789031

Todorovic M, Gutmann MU, Corander J, Rinke P (2019)
Bayesian inference of atomistic structure in functional materials
npj Comput. Mater., 5, 35

Tonby K, Mortensen R, Ruhwald M, Dyrhol-Riise AM, Jenum S (2019)
KLRG1-Expressing CD4 T Cells Are Reduced in Tuberculosis Patients Compared to Healthy Mycobacterium tuberculosis-Infected Subjects, but Increase With Treatment
J Infect Dis, 220 (1), 174-176
DOI 10.1093/infdis/jiz056, PubMed 30888024

Tonkin-Hill G, Lees JA, Bentley SD, Frost SDW, Corander J (2019)
Fast hierarchical Bayesian analysis of population structure
Nucleic Acids Res, 47 (11), 5539-5549
DOI 10.1093/nar/gkz361, PubMed 31076776

Torp MK, Yang K, Ranheim T, Husø Lauritzen K, Alfsnes K, Vinge LE, Aukrust P, Stensløkken KO, Yndestad A, Sandanger Ø (2019)
Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts
Front Immunol, 10, 1285
DOI 10.3389/fimmu.2019.01285, PubMed 31244838

Trevisan C, Sotiraki S, Laranjo-González M, Dermauw V, Wang Z, Kärssin A, Cvetkovikj A, Winkler AS, Abraham A, Bobić B, Lassen B, Cretu CM, Vasile C, Arvanitis D, Deksne G, Boro I, Kucsera I, Karamon J, Stefanovska J, Koudela B, Pavlova MJ, Varady M, Pavlak M, Šarkūnas M, Kaminski M et al. (2019)
Correction to: Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe
Parasit Vectors, 12 (1), 84
DOI 10.1186/s13071-019-3328-8, PubMed 30777134

Troseid M (2019)
Bone Marrow Transplantation - a cure for HIV?
Tidsskr. Nor. Laegeforen., 139 (7), 580

Trøseid M (2019)
Bone marrow transplantation – a cure for HIV?
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0199, PubMed 30969050

Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965

Tschirhart N, Straiton M, Ottersen T, Winkler AS (2019)
"Living like I am in Thailand": stress and coping strategies among Thai migrant masseuses in Oslo, Norway
BMC Womens Health, 19 (1), 139
DOI 10.1186/s12905-019-0836-9, PubMed 31729987

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, Aukrust P, Christensen G, Skjønsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Budaj A, Cornel JH, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L, PLATO Investigators (2019)
ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial
Atherosclerosis, 293, 35-41
DOI 10.1016/j.atherosclerosis.2019.11.031, PubMed 31835039

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L, PLATO Investigators (2019)
Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, 39 (2), 294-302
DOI 10.1161/ATVBAHA.118.311042, PubMed 30580572

Ueland T, Aukrust P, Caidahl K (2019)
CCL21 and prognosis in acute coronary syndrome
Aging (Albany NY), 11 (21), 9225-9226
DOI 10.18632/aging.102443, PubMed 31694981

Ueland T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2019)
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982

van der Vorst EPC, Daissormont I, Aslani M, Seijkens T, Wijnands E, Lutgens E, Duchene J, Santovito D, Döring Y, Halvorsen B, Aukrust P, Weber C, Höpken UE, Biessen EAL (2019)
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development
Thromb Haemost, 120 (2), 344-347
DOI 10.1055/s-0039-3400746, PubMed 31837653

Vorkapic D, Mitterer F, Pressler K, Leitner DR, Anonsen JH, Liesinger L, Mauerhofer LM, Kuehnast T, Toeglhofer M, Schulze A, Zingl FG, Feldman MF, Reidl J, Birner-Gruenberger R, Koomey M, Schild S (2019)
A Broad Spectrum Protein Glycosylation System Influences Type II Protein Secretion and Associated Phenotypes in Vibrio cholerae
Front Microbiol, 10, 2780
DOI 10.3389/fmicb.2019.02780, PubMed 31849912

Wailan AM, Coll F, Heinz E, Tonkin-Hill G, Corander J, Feasey NA, Thomson NR (2019)
rPinecone: Define sub-lineages of a clonal expansion via a phylogenetic tree
Microb Genom, 5 (4)
DOI 10.1099/mgen.0.000264, PubMed 30920366

Watila MM, Xiao F, Keezer MR, Miserocchi A, Winkler AS, McEvoy AW, Sander JW (2019)
Epilepsy surgery in low- and middle-income countries: A scoping review
Epilepsy Behav, 92, 311-326
DOI 10.1016/j.yebeh.2019.01.001, PubMed 30738248

Wedervang-Resell K, Friis S, Lonning V, Smelror RE, Johannessen C, Reponen EJ, Lyngstad SH, Lekva T, Aukrust P, Ueland T, Andreassen OA, Agartz I, Myhre AM (2019)
Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
DOI 10.1016/j.psyneuen.2019.104513, PubMed 31761332

Weinert LA, Chaudhuri RR, Wang J, Peters SE, Corander J, Jombart T, Baig A, Howell KJ, Vehkala M, Välimäki N, Harris D, Chieu TTB, Van Vinh Chau N, Campbell J, Schultsz C, Parkhill J, Bentley SD, Langford PR, Rycroft AN, Wren BW, Farrar J, Baker S, Hoa NT, Holden MTG, Tucker AW et al. (2019)
Publisher Correction: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis
Nat Commun, 10 (1), 5326
DOI 10.1038/s41467-019-13138-w, PubMed 31757940

Winkler AS (2019)
The growing burden of neurological disorders in low-income and middle-income countries: priorities for policy making
Lancet Neurol, 19 (3), 200-202
DOI 10.1016/S1474-4422(19)30476-4, PubMed 31813849

Xu K, Chatzitakis A, Risbakk S, Yang M, Backe PH, Grandcolas M, Bjørås M, Norby T (2019)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catalysis Today, 0, 1-6 (in press)
DOI 10.1016/j.cattod.2019.12.031, PublikaID 337

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD⁺ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

Zandi H, Petronijevic N, Mdala I, Kristoffersen AK, Enersen M, Rôças IN, Siqueira JF, Ørstavik D (2019)
Outcome of Endodontic Retreatment Using 2 Root Canal Irrigants and Influence of Infection on Healing as Determined by a Molecular Method: A Randomized Clinical Trial
J Endod, 45 (9), 1089-1098.e5
DOI 10.1016/j.joen.2019.05.021, PubMed 31300248

Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, 104 (5), e229
DOI 10.3324/haematol.2019.220533, PubMed 31040234

Zhang Z, Manaf A, Li Y, Perez SP, Suganthan R, Dahl JA, Bjørås M, Klungland A (2019)
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
Mol Neurobiol, 57 (2), 997-1008
DOI 10.1007/s12035-019-01777-5, PubMed 31654318

Zöllner R, Cronenberg T, Kouzel N, Welker A, Koomey M, Maier B (2019)
Type IV Pilin Post-Translational Modifications Modulate Material Properties of Bacterial Colonies
Biophys J, 116 (5), 938-947
DOI 10.1016/j.bpj.2019.01.020, PubMed 30739725

Publications 2018

Aas M, Dieset I, Mørch R, Steen NE, Hope S, Reponen EJ, Laskemoen JF, Ueland T, Aukrust P, Melle I, Agartz I, Andreassen OA (2018)
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813

Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H (2018)
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151

Åberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Østensen A, Karlsen TH, Nordin A (2018)
Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
Liver Transpl, 24 (9), 1252-1259
DOI 10.1002/lt.25305, PubMed 30120902

Abraityte A, Aukrust P, Kou L, Anand IS, Young J, Mcmurray JJV, van Veldhuisen DJ, Gullestad L, Ueland T (2018)
T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF
Clin Res Cardiol, 108 (2), 133-141
DOI 10.1007/s00392-018-1331-2, PubMed 30051179

Abudahab K, Prada JM, Yang Z, Bentley SD, Croucher NJ, Corander J, Aanensen DM (2018)
PANINI: Pangenome Neighbour Identification for Bacterial Populations
Microb Genom, 5 (4)
DOI 10.1099/mgen.0.000220, PubMed 30465642

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2018)
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 9 (1), 5381
DOI 10.1038/s41467-018-07797-4, PubMed 30568191

Alexeeva M, Guragain P, Tesfahun AN, Tomkuvienė M, Arshad A, Gerasimaitė R, Rukšėnaitė A, Urbanavičiūtė G, Bjørås M, Laerdahl JK, Klungland A, Klimašauskas S, Bjelland S (2018)
Excision of the doubly methylated base N⁴,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Philos Trans R Soc Lond B Biol Sci, 373 (1748)
DOI 10.1098/rstb.2017.0337, PubMed 29685966

Alfsnes K, Frye SA, Eriksson J, Eldholm V, Brynildsrud OB, Bohlin J, Harrison OB, Hood DW, Maiden MCJ, Tønjum T, Ambur OH (2018)
A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis
Microb Genom, 4 (11)
DOI 10.1099/mgen.0.000222, PubMed 30251949

Aresvik DM, Øverland T, Lima K, Pettersen RD, Abrahamsen TG (2018)
Lymphocyte Apoptosis and FAS Expression in Patients with 22q11.2 Deletion Syndrome
J Clin Immunol, 39 (1), 65-74
DOI 10.1007/s10875-018-0579-7, PubMed 30569262

Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
J Acquir Immune Defic Syndr, 78 (4), 450-457
DOI 10.1097/QAI.0000000000001693, PubMed 29874201

Arnold BJ, Gutmann MU, Grad YH, Sheppard SK, Corander J, Lipsitch M, Hanage WP (2018)
Weak Epistasis May Drive Adaptation in Recombining Bacteria
Genetics, 208 (3), 1247-1260
DOI 10.1534/genetics.117.300662, PubMed 29330348

Arora S, Andreassen AK, Karason K, Gustafsson F, Eiskjær H, Bøtker HE, Rådegran G, Gude E, Ioanes D, Solbu D, Dellgren G, Ueland T, Aukrust P, Gullestad L, SCHEDULE (Scandinavian Heart Transplant Everolimus De Novo Study With Early Calcineurin Inhibitors Avoidance) Investigators (2018)
Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Heart Transplant Recipients
Circ Heart Fail, 11 (9), e004050
DOI 10.1161/CIRCHEARTFAILURE.117.004050, PubMed 30354362

Arredondo-Alonso S, Rogers MRC, Braat JC, Verschuuren TD, Top J, Corander J, Willems RJL, Schürch AC (2018)
mlplasmids: a user-friendly tool to predict plasmid- and chromosome-derived sequences for single species
Microb Genom, 4 (11)
DOI 10.1099/mgen.0.000224, PubMed 30383524

Askeland G, Dosoudilova Z, Rodinova M, Klempir J, Liskova I, Kuśnierczyk A, Bjørås M, Nesse G, Klungland A, Hansikova H, Eide L (2018)
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
Sci Rep, 8 (1), 9817
DOI 10.1038/s41598-018-27985-y, PubMed 29959348

Askeland G, Rodinova M, Štufková H, Dosoudilova Z, Baxa M, Smatlikova P, Bohuslavova B, Klempir J, Nguyen TD, Kuśnierczyk A, Bjørås M, Klungland A, Hansikova H, Ellederova Z, Eide L (2018)
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
Dis Model Mech, 11 (10)
DOI 10.1242/dmm.035949, PubMed 30254085

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2018)
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BMC Gastroenterol, 18 (1), 27
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Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279

Otterdal K, Berg A, Michelsen AE, Patel S, Tellevik MG, Haanshuus CG, Fevang B, Aukrust P, Langeland N, Ueland T (2018)
Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria
BMC Infect Dis, 18 (1), 670
DOI 10.1186/s12879-018-3593-8, PubMed 30563486

Pessia A, Corander J (2018)
Kpax3: Bayesian bi-clustering of large sequence datasets
Bioinformatics, 34 (12), 2132-2133
DOI 10.1093/bioinformatics/bty056, PubMed 29425273

Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
J Hepatol, 69 (2), 368-377
DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678

Puranen S, Pesonen M, Pensar J, Xu YY, Lees JA, Bentley SD, Croucher NJ, Corander J (2018)
SuperDCA for genome-wide epistasis analysis
Microb Genom, 4 (6)
DOI 10.1099/mgen.0.000184, PubMed 29813016

Quist-Paulsen E, Aukrust P, Kran AB, Dunlop O, Ormaasen V, Stiksrud B, Midttun Ø, Ueland T, Ueland PM, Mollnes TE, Dyrhol-Riise AM (2018)
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234

Reiseter S, Gunnarsson R, Mogens Aaløkken T, Lund MB, Mynarek G, Corander J, Haydon J, Molberg Ø (2018)
Progression and mortality of interstitial lung disease in mixed connective tissue disease: a long-term observational nationwide cohort study
Rheumatology (Oxford), 57 (2), 255-262
DOI 10.1093/rheumatology/kex077, PubMed 28379478

Reiten MR, Malachin G, Kommisrud E, Østby GC, Waterhouse KE, Krogenæs AK, Kusnierczyk A, Bjørås M, Jalland CMO, Nekså LH, Røed SS, Stenseth EB, Myromslien FD, Zeremichael TT, Bakkebø MK, Espenes A, Tranulis MA (2018)
Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein
Front Mol Biosci, 5, 1
DOI 10.3389/fmolb.2018.00001, PubMed 29417049

Richardson EJ, Bacigalupe R, Harrison EM, Weinert LA, Lycett S, Vrieling M, Robb K, Hoskisson PA, Holden MTG, Feil EJ, Paterson GK, Tong SYC, Shittu A, van Wamel W, Aanensen DM, Parkhill J, Peacock SJ, Corander J, Holmes M, Fitzgerald JR (2018)
Gene exchange drives the ecological success of a multi-host bacterial pathogen
Nat Ecol Evol, 2 (9), 1468-1478
DOI 10.1038/s41559-018-0617-0, PubMed 30038246

Rognlien AGW, Wollen EJ, Atneosen-Åsegg M, Suganthan R, Bjørås M, Saugstad OD (2018)
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
J Perinat Med, 47 (1), 114-124
DOI 10.1515/jpm-2018-0172, PubMed 30020889

Sane Schepisi M, Navarra A, Altet Gomez MN, Dudnyk A, Dyrhol-Riise AM, Esteban J, Giorgetti PF, Gualano G, Guglielmetti L, Heyckendorf J, Kaluzhenina A, Lange B, Lange C, Manika K, Miah J, Nanovic Z, Pontali E, Prego MR, Solovic I, Tiberi S, Palmieri F, Girardi E (2018)
Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study
Open Forum Infect Dis, 6 (1), ofy337
DOI 10.1093/ofid/ofy337, PubMed 30697572

Schein YL, Madebo T, Andersen HE, Arnesen TM, Dyrhol-Riise AM, Tveiten H, White RA, Winje BA (2018)
Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study
BMC Infect Dis, 18 (1), 587
DOI 10.1186/s12879-018-3468-z, PubMed 30453946

Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
J Intern Med, 284 (1), 78-91
DOI 10.1111/joim.12750, PubMed 29498764

Shekhar S, Khan R, Ferreira DM, Mitsi E, German E, Rørvik GH, Berild D, Schenck K, Kwon K, Petersen F (2018)
Antibodies Reactive to Commensal Streptococcus mitis Show Cross-Reactivity With Virulent Streptococcus pneumoniae Serotypes
Front Immunol, 9, 747
DOI 10.3389/fimmu.2018.00747, PubMed 29713324

Sikkeland LIB, Borander AK, Voie ØA, Aass HCD, Øvstebø R, Aukrust P, Longva K, Alexis NE, Kongerud J, Ueland T (2018)
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L (2018)
Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
Open Forum Infect Dis, 5 (2), ofy002
DOI 10.1093/ofid/ofy002, PubMed 29410975

Sipola A, Marttinen P, Corander J (2018)
Bacmeta: simulator for genomic evolution in bacterial metapopulations
Bioinformatics, 34 (13), 2308-2310
DOI 10.1093/bioinformatics/bty093, PubMed 29474733

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sørensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB (2018)
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254

Smet A, Yahara K, Rossi M, Tay A, Backert S, Armin E, Fox JG, Flahou B, Ducatelle R, Haesebrouck F, Corander J (2018)
Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence
ISME J, 12 (10), 2518-2531
DOI 10.1038/s41396-018-0199-5, PubMed 29942073

Sokolova M, Sahraoui A, Høyem M, Øgaard J, Lien E, Aukrust P, Yndestad A, Ranheim T, Scholz H (2018)
NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction
Am J Physiol Endocrinol Metab, 315 (5), E912-E923
DOI 10.1152/ajpendo.00461.2017, PubMed 30016155

Sørbye IK, Andersen HB, Melin E, Nordøy I (2018)
[A pregnant woman with headache and fever]
Tidsskr Nor Laegeforen, 138 (4)
DOI 10.4045/tidsskr.17.0383, PubMed 29460598

Steineger J, Ueland T, Aukrust P, Michelsen A, Osnes T, Heimdal K, Dheyauldeen S (2018)
Pentraxin 3 level is elevated in hereditary hemorrhagic telangiectasia and reflects the severity of disease-associated epistaxis
Laryngoscope, 129 (1), E44-E49
DOI 10.1002/lary.27548, PubMed 30329172

Tonkin-Hill G, Lees JA, Bentley SD, Frost SDW, Corander J (2018)
RhierBAPS: An R implementation of the population clustering algorithm hierBAPS
Wellcome Open Res, 3, 93
DOI 10.12688/wellcomeopenres.14694.1, PubMed 30345380

Top J, Sinnige JC, Brouwer EC, Werner G, Corander J, Severin JA, Jansen R, Bathoorn E, Bonten MJM, Rossen JWA, Willems RJL (2018)
Identification of a Novel Genomic Island Associated with vanD-Type Vancomycin Resistance in Six Dutch Vancomycin-Resistant Enterococcus faecium Isolates
Antimicrob Agents Chemother, 62 (3)
DOI 10.1128/AAC.01793-17, PubMed 29311068

Traaen GM, Aakerøy L, Hunt TE, Øverland B, Lyseggen E, Aukrust P, Ueland T, Helle-Valle T, Steinshamn S, Edvardsen T, Khiabani Zaré H, Aakhus S, Akre H, Anfinsen OG, Loennechen JP, Gullestad L (2018)
Treatment of sleep apnea in patients with paroxysmal atrial fibrillation: design and rationale of a randomized controlled trial
Scand Cardiovasc J, 52 (6), 372-377
DOI 10.1080/14017431.2019.1567933, PubMed 30638392

Trevisan C, Sotiraki S, Laranjo-González M, Dermauw V, Wang Z, Kärssin A, Cvetkovikj A, Winkler AS, Abraham A, Bobić B, Lassen B, Cretu CM, Vasile C, Arvanitis D, Deksne G, Boro I, Kucsera I, Karamon J, Stefanovska J, Koudela B, Pavlova MJ, Varady M, Pavlak M, Šarkūnas M, Kaminski M et al. (2018)
Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe
Parasit Vectors, 11 (1), 569
DOI 10.1186/s13071-018-3153-5, PubMed 30376899

Tronstad RR, Polushina T, Brattbakk HR, Stansberg C, von Volkmann HL, Hanevik K, Ellinghaus E, Jørgensen SF, Ersland KM, Pham KD, Gilja OH, Hovdenak N, Hausken T, Vatn MH, Franke A, Knappskog PM, Le Hellard S, Karlsen TH, Fiskerstrand T (2018)
Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea
Scand J Gastroenterol, 53 (10-11), 1264-1273
DOI 10.1080/00365521.2018.1521867, PubMed 30353760

Troseid M, Nordoy I, Fevang B, Aukrust P (2018)
Tenders for HIV medicines are not academically justified
Tidsskr. Nor. Laegeforen., 138 (20), 1912-1913

Trøseid M, Nordøy I, Fevang B, Aukrust P (2018)
Tendering for HIV drugs is not clinically justified
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0808, PubMed 30539614

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Aukrust P, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Wallentin L, PLATO (Platelet Inhibition and Patient Outcomes) Trial Investigators (2018)
Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.007009, PubMed 29330256

Ueland T, Gullestad L, Kou L, Aukrust P, Anand IS, Broughton MN, McMurray JJ, van Veldhuisen DJ, Warren DJ, Bolstad N (2018)
Pro-gastrin-releasing peptide and outcome in patients with heart failure and anaemia: results from the RED-HF study
ESC Heart Fail, 5 (6), 1052-1059
DOI 10.1002/ehf2.12312, PubMed 30145817

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Aukrust P, Gullestad L, Halvorsen B, Yndestad A (2018)
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Open Heart, 5 (2), e000765
DOI 10.1136/openhrt-2017-000765, PubMed 30258647

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Holven KB, Aukrust P, Gullestad L, Yndestad A, Halvorsen B (2018)
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Int J Cardiol, 274, 348-350
DOI 10.1016/j.ijcard.2018.06.093, PubMed 29961573

Vinkeles Melchers NVS, Mollenkopf S, Colebunders R, Edlinger M, Coffeng LE, Irani J, Zola T, Siewe JN, de Vlas SJ, Winkler AS, Stolk WA (2018)
Burden of onchocerciasis-associated epilepsy: first estimates and research priorities
Infect Dis Poverty, 7 (1), 101
DOI 10.1186/s40249-018-0481-9, PubMed 30253788

Wang N, Anonsen JH, Viburiene R, Lam JS, Vik Å, Koomey M (2018)
Disrupted Synthesis of a Di-N-acetylated Sugar Perturbs Mature Glycoform Structure and Microheterogeneity in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica
J Bacteriol, 201 (1)
DOI 10.1128/JB.00522-18, PubMed 30322851

Winje BA, White R, Syre H, Skutlaberg DH, Oftung F, Mengshoel AT, Blix HS, Brantsæter AB, Holter EK, Handal N, Simonsen GS, Afset JE, Bakken Kran AM (2018)
Stratification by interferon-γ release assay level predicts risk of incident TB
Thorax, 73 (7), 652-661
DOI 10.1136/thoraxjnl-2017-211147, PubMed 29622693

Winkler AS, Klohe K, Schmidt V, Haavardsson I, Abraham A, Prodjinotho UF, Ngowi B, Sikasunge C, Noormahomed E, Amuasi J, Kaducu J, Ngowi H, Abele-Ridder B, Harrison WE, Prazeres da Costa C (2018)
Neglected tropical diseases - the present and the future
Tidsskr Nor Laegeforen, 138 (3)
DOI 10.4045/tidsskr.17.0678, PubMed 29411594

Xu Y, Puranen S, Corander J, Kabashima Y (2018)
Inverse finite-size scaling for high-dimensional significance analysis
Phys Rev E, 97 (6-1), 062112
DOI 10.1103/PhysRevE.97.062112, PubMed 30011500

Zandi H, Kristoffersen AK, Ørstavik D, Rôças IN, Siqueira JF, Enersen M (2018)
Microbial Analysis of Endodontic Infections in Root-filled Teeth with Apical Periodontitis before and after Irrigation Using Pyrosequencing
J Endod, 44 (3), 372-378
DOI 10.1016/j.joen.2017.11.019, PubMed 29306533

Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, Online ahead of print (in press) (Retracted)
DOI 10.3324/haematol.2018.189399, PubMed 29748445

Zusinaite E, Ianevski A, Niukkanen D, Poranen MM, Bjørås M, Afset JE, Tenson T, Velagapudi V, Merits A, Kainov DE (2018)
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents
Viruses, 10 (8)
DOI 10.3390/v10080423, PubMed 30103549

Publications 2017

Aabakken L, Karlsen TH, Albert J, Arvanitakis M, Chazouilleres O, Dumonceau JM, Färkkilä M, Fickert P, Hirschfield GM, Laghi A, Marzioni M, Fernandez M, Pereira SP, Pohl J, Poley JW, Ponsioen CY, Schramm C, Swahn F, Tringali A, Hassan C (2017)
Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline
Endoscopy, 49 (6), 588-608
DOI 10.1055/s-0043-107029, PubMed 28420030

Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I (2017)
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247

Abraityte A, Lunde IG, Askevold ET, Michelsen AE, Christensen G, Aukrust P, Yndestad A, Fiane A, Andreassen A, Aakhus S, Dahl CP, Gullestad L, Broch K, Ueland T (2017)
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
Gut, 67 (8), 1517-1524
DOI 10.1136/gutjnl-2016-313598, PubMed 28779025

Andam CP, Mitchell PK, Callendrello A, Chang Q, Corander J, Chaguza C, McGee L, Beall BW, Hanage WP (2017)
Genomic Epidemiology of Penicillin-Nonsusceptible Pneumococci with Nonvaccine Serotypes Causing Invasive Disease in the United States
J Clin Microbiol, 55 (4), 1104-1115
DOI 10.1128/JCM.02453-16, PubMed 28100596

Anonsen JH, Børud B, Vik Å, Viburiene R, Koomey M (2017)
Structural and genetic analyses of glycan O-acetylation in a bacterial protein glycosylation system: evidence for differential effects on glycan chain length
Glycobiology, 27 (9), 888-899
DOI 10.1093/glycob/cwx032, PubMed 28460017

Anumala UR, Waaler J, Nkizinkiko Y, Ignatev A, Lazarow K, Lindemann P, Olsen PA, Murthy S, Obaji E, Majouga AG, Leonov S, von Kries JP, Lehtiö L, Krauss S, Nazaré M (2017)
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568

Auensen A, Hussain AI, Falk RS, Walle-Hansen MM, Bye J, Pettersen KI, Aukrust P, Ueland T, Gullestad LL (2017)
Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis
PLoS One, 12 (6), e0179304
DOI 10.1371/journal.pone.0179304, PubMed 28604834

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T (2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312

Bakke V, Sporsem H, Von der Lippe E, Nordøy I, Lao Y, Nyrerød HC, Sandvik L, Hårvig KR, Bugge JF, Helset E (2017)
Vancomycin levels are frequently subtherapeutic in critically ill patients: a prospective observational study
Acta Anaesthesiol Scand, 61 (6), 627-635
DOI 10.1111/aas.12897, PubMed 28444760

Batmanov K, Wang W, Bjørås M, Delabie J, Wang J (2017)
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma
Sci Rep, 7 (1), 7040
DOI 10.1038/s41598-017-07226-4, PubMed 28765546

Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL (2017)
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371

Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
DOI 10.1152/ajpgi.00124.2017, PubMed 29212771

Beyene GT, Kalayou S, Riaz T, Tonjum T (2017)
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
BMC Microbiol, 17 (1), 96
DOI 10.1186/s12866-017-1004-8, PubMed 28431522

Birhanu AG, Yimer SA, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2017)
N_ε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated
J Proteome Res, 16 (11), 4045-4059
DOI 10.1021/acs.jproteome.7b00429, PubMed 28920697

Bj Rås KØ, Sousa MML, Sharma A, Fonseca DM, S Gaard CK, Bj Rås M, Otterlei M (2017)
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication
Nucleic Acids Res, 45 (14), 8291-8301
DOI 10.1093/nar/gkx476, PubMed 28575236

Bjerva M, Berild D, Jacobsen D (2017)
[A well-trained man with mechanical aortic valve and leg pain]
Tidsskr Nor Laegeforen, 137 (2), 113-116
DOI 10.4045/tidsskr.15.1337, PubMed 28127075

Bosshard M, Aprigliano R, Gattiker C, Palibrk V, Markkanen E, Backe PH, Pellegrino S, Raymond FL, Froyen G, Altmeyer M, Bjørås M, Dianov GL, van Loon B (2017)
Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability
Sci Rep, 7 (1), 15050
DOI 10.1038/s41598-017-15380-y, PubMed 29118367

Brekke K, Sommerfelt M, Ökvist M, Dyrhol-Riise AM, Kvale D (2017)
The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study
BMC Infect Dis, 17 (1), 228
DOI 10.1186/s12879-017-2316-x, PubMed 28340570

Carabin H, Winkler AS, Dorny P (2017)
Taenia solium cysticercosis and taeniosis: Achievements from the past 10 years and the way forward
PLoS Negl Trop Dis, 11 (4), e0005478
DOI 10.1371/journal.pntd.0005478, PubMed 28426664

Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E (2017)
Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis
Am J Pathol, 188 (3), 627-639
DOI 10.1016/j.ajpath.2017.11.010, PubMed 29248458

Castañeda-García A, Prieto AI, Rodríguez-Beltrán J, Alonso N, Cantillon D, Costas C, Pérez-Lago L, Zegeye ED, Herranz M, Plociński P, Tonjum T, García de Viedma D, Paget M, Waddell SJ, Rojas AM, Doherty AJ, Blázquez J (2017)
A non-canonical mismatch repair pathway in prokaryotes
Nat Commun, 8, 14246
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Chewapreecha C, Holden MT, Vehkala M, Välimäki N, Yang Z, Harris SR, Mather AE, Tuanyok A, De Smet B, Le Hello S, Bizet C, Mayo M, Wuthiekanun V, Limmathurotsakul D, Phetsouvanh R, Spratt BG, Corander J, Keim P, Dougan G, Dance DA, Currie BJ, Parkhill J, Peacock SJ (2017)
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Nordin A, Åberg F, Pukkala E, Pedersen CR, Storm HH, Rasmussen A, Bennet W, Olausson M, Wilczek H, Ericzon BG, Tretli S, Line PD, Karlsen TH, Boberg KM, Isoniemi H (2017)
Decreasing incidence of cancer after liver transplantation-A Nordic population-based study over 3 decades
Am J Transplant, 18 (4), 952-963
DOI 10.1111/ajt.14507, PubMed 28925583

Norheim G, Seterelv S, Arnesen TM, Mengshoel AT, Tønjum T, Rønning JO, Eldholm V (2017)
Tuberculosis Outbreak in an Educational Institution in Norway
J Clin Microbiol, 55 (5), 1327-1333
DOI 10.1128/JCM.01152-16, PubMed 28202795

Norum HM, Broch K, Michelsen AE, Lunde IG, Lekva T, Abraityte A, Dahl CP, Fiane AE, Andreassen AK, Christensen G, Aakhus S, Aukrust P, Gullestad L, Ueland T (2017)
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304

Nymo SH, Aukrust P, Kjekshus J, McMurray JJ, Cleland JG, Wikstrand J, Muntendam P, Wienhues-Thelen U, Latini R, Askevold ET, Gravning J, Dahl CP, Broch K, Yndestad A, Gullestad L, Ueland T, CORONA Study Group (2017)
Limited Added Value of Circulating Inflammatory Biomarkers in Chronic Heart Failure
JACC Heart Fail, 5 (4), 256-264
DOI 10.1016/j.jchf.2017.01.008, PubMed 28359413

O'Hara SP, Karlsen TH, LaRusso NF (2017)
Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?
Gut, 66 (11), 1873-1877
DOI 10.1136/gutjnl-2017-314249, PubMed 28733279

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262

Ottesen AH, Carlson CR, Louch WE, Dahl MB, Sandbu RA, Johansen RF, Jarstadmarken H, Bjørås M, Høiseth AD, Brynildsen J, Sjaastad I, Stridsberg M, Omland T, Christensen G, Røsjø H (2017)
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ Heart Fail, 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675, PubMed 28209766

Pawar T, Bjørås M, Klungland A, Eide L (2017)
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
Mitochondrion, 40, 16-28
DOI 10.1016/j.mito.2017.09.002, PubMed 28893634

Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Nucleic Acids Res, 45 (11), 6471-6485
DOI 10.1093/nar/gkx263, PubMed 28407100

Pensar J, Nyman H, Corander J (2017)
Structure Learning of Contextual Markov Networks using Marginal Pseudo-likelihood
Scand. J. Stat., 44 (2), 455-479

Pensar J, Nyman H, Niiranen J, Corander J (2017)
Marginal Pseudo-Likelihood Learning of Discrete Markov Network Structures
Bayesian Anal., 12 (4), 1195-1215

Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K (2017)
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
Oncotarget, 8 (14), 22606-22615
DOI 10.18632/oncotarget.15146, PubMed 28186983

Prebensen C, Trøseid M, Ueland T, Dahm A, Sandset PM, Aaberge I, Waalen K, Dyrhol-Riise AM, Taskén K, Kvale D (2017)
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
PLoS One, 12 (5), e0176527
DOI 10.1371/journal.pone.0176527, PubMed 28464042

Rasmussen BK, Hansen S, Laursen RJ, Kosteljanetz M, Schultz H, Nørgård BM, Guldberg R, Gradel KO (2017)
Epidemiology of glioma: clinical characteristics, symptoms, and predictors of glioma patients grade I-IV in the the Danish Neuro-Oncology Registry
J Neurooncol, 135 (3), 571-579
DOI 10.1007/s11060-017-2607-5, PubMed 28861666

Reiseter S, Gunnarsson R, Corander J, Haydon J, Lund MB, Aaløkken TM, Taraldsrud E, Hetlevik SO, Molberg Ø (2017)
Disease evolution in mixed connective tissue disease: results from a long-term nationwide prospective cohort study
Arthritis Res Ther, 19 (1), 284
DOI 10.1186/s13075-017-1494-7, PubMed 29268795

Retterstøl K, Narverud I, Selmer R, Berge KE, Osnes IV, Ulven SM, Halvorsen B, Aukrust P, Holven KB, Iversen PO (2017)
Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics
Lipids Health Dis, 16 (1), 115
DOI 10.1186/s12944-017-0511-9, PubMed 28606150

Roaldsnes E, Eikeland R, Berild D (2017)
Lyme neuroborreliosis in cases of non-specific neurological symptoms
Tidsskr Nor Laegeforen, 137 (2), 101-104
DOI 10.4045/tidsskr.15.1115, PubMed 28127071

Rodrigues RCV, Zandi H, Kristoffersen AK, Enersen M, Mdala I, Ørstavik D, Rôças IN, Siqueira JF (2017)
Influence of the Apical Preparation Size and the Irrigant Type on Bacterial Reduction in Root Canal-treated Teeth with Apical Periodontitis
J Endod, 43 (7), 1058-1063
DOI 10.1016/j.joen.2017.02.004, PubMed 28483164

Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M (2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Sci Rep, 7 (1), 4384
DOI 10.1038/s41598-017-04472-4, PubMed 28663564

Rosati E, Dowds CM, Liaskou E, Henriksen EKK, Karlsen TH, Franke A (2017)
Overview of methodologies for T-cell receptor repertoire analysis
BMC Biotechnol, 17 (1), 61
DOI 10.1186/s12896-017-0379-9, PubMed 28693542

Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A (2017)
Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci
Gut Microbes, 9 (1), 68-75
DOI 10.1080/19490976.2017.1356979, PubMed 28816579

Rydning SL, Backe PH, Sousa MML, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK (2017)
Novel UCHL1 mutations reveal new insights into ubiquitin processing
Hum Mol Genet, 26 (6), 1031-1040
DOI 10.1093/hmg/ddw391, PubMed 28007905

Rydning SL, Backe PH, Sousa MML, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK (2017)
Novel UCHL1 mutations reveal new insights into ubiquitin processing
Hum Mol Genet, 26 (6), 1217-1218
DOI 10.1093/hmg/ddx072, PubMed 28334853

Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W et al. (2017)
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
Nat Med, 23 (8), 954-963
DOI 10.1038/nm.4360, PubMed 28671689

Samuelsen Ø, Overballe-Petersen S, Bjørnholt JV, Brisse S, Doumith M, Woodford N, Hopkins KL, Aasnæs B, Haldorsen B, Sundsfjord A, Norwegian Study Group on CPE (2017)
Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014
PLoS One, 12 (11), e0187832
DOI 10.1371/journal.pone.0187832, PubMed 29141051

Scheffler K, Rachek L, You P, Rowe AD, Wang W, Kuśnierczyk A, Kittelsen L, Bjørås M, Eide L (2017)
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis
DNA Repair (Amst), 61, 56-62
DOI 10.1016/j.dnarep.2017.11.008, PubMed 29207315

Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang SC, Allan DS, Davidson-Moncada JK, Dickinson RE, Holmes TD, Hsu AP, Townsley D, Winkler T, Wang W, Aukrust P, Nordøy I, Calvo KR, Holland SM, Collin M, Dunbar CE, Bryceson YT (2017)
Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells
Blood, 129 (14), 1927-1939
DOI 10.1182/blood-2016-08-734236, PubMed 28209719

Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
Physiol Rep, 5 (4)
DOI 10.14814/phy2.13117, PubMed 28219981

Seecharran T, Kalin-Manttari L, Koskela K, Nikkari S, Dickins B, Corander J, Skurnik M, McNally A (2017)
Phylogeographic separation and formation of sexually discrete lineages in a global population of Yersinia pseudotuberculosis
Microb Genom, 3 (10), e000133
DOI 10.1099/mgen.0.000133, PubMed 29177091

Shahini N, Michelsen AE, Nilsson PH, Ekholt K, Gullestad L, Broch K, Dahl CP, Aukrust P, Ueland T, Mollnes TE, Yndestad A, Louwe MC (2017)
The alternative complement pathway is dysregulated in patients with chronic heart failure
Sci Rep, 7, 42532
DOI 10.1038/srep42532, PubMed 28195242

Shetelig C, Limalanathan S, Eritsland J, Hoffmann P, Seljeflot I, Gran JM, Aukrust P, Ueland T, Andersen GØ (2017)
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034, PubMed 28253327

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2017)
Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia
Eur J Clin Invest, 48 (1)
DOI 10.1111/eci.12865, PubMed 29171871

Skwark MJ, Croucher NJ, Puranen S, Chewapreecha C, Pesonen M, Xu YY, Turner P, Harris SR, Beres SB, Musser JM, Parkhill J, Bentley SD, Aurell E, Corander J (2017)
Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
PLoS Genet, 13 (2), e1006508
DOI 10.1371/journal.pgen.1006508, PubMed 28207813

Smeland TE, Müller F, Blomfeldt A, Stavem K, Aamot HV (2017)
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections
APMIS, 125 (10), 927-932
DOI 10.1111/apm.12734, PubMed 28736863

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S (2017)
TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer
Mol Cancer Res, 16 (3), 543-553
DOI 10.1158/1541-7786.MCR-17-0362, PubMed 29222171

Spencer PS, Schmutzhard E, Winkler AS (2017)
Nodding Syndrome in the Spotlight - Placing Recent Findings in Perspective
Trends Parasitol, 33 (7), 490-492
DOI 10.1016/j.pt.2017.05.001, PubMed 28596064

Stav-Noraas TE, Edelmann RJ, Poulsen LC, Sundnes O, Phung D, Küchler AM, Müller F, Kamen AA, Haraldsen G, Kaarbø M, Hol J (2017)
Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery
J Immunol, 198 (8), 3318-3325
DOI 10.4049/jimmunol.1600054, PubMed 28258201

Stensvold HJ, Lang AM, Strommen K, Abrahamsen TG, Ogland B, Pripp AH, Ronnestad AE (2017)
Strictly controlled glucose infusion rates are associated with a reduced risk of hyperglycaemia in extremely low birth weight preterm infants
Acta Paediatr, 107 (3), 442-449
DOI 10.1111/apa.14164, PubMed 29172239

Tadei A, Pensar J, Corander J, Finnilä K, Santtila P, Antfolk J (2017)
A Bayesian Decision-Support Tool for Child Sexual Abuse Assessment and Investigation
Sex Abuse, 31 (4), 374-396
DOI 10.1177/1079063217732791, PubMed 28933247

Taraldsrud E, Fevang B, Jørgensen SF, Moltu K, Hilden V, Taskén K, Aukrust P, Myklebust JH, Olweus J (2017)
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
J Autoimmun, 81, 110-119
DOI 10.1016/j.jaut.2017.04.004, PubMed 28476239

Tronstad RR, Kummen M, Holm K, von Volkmann HL, Anmarkrud JA, Høivik ML, Moum B, Gilja OH, Hausken T, Baines J, Karlsen TH, Fiskerstrand T, Hov JR (2017)
Guanylate Cyclase C Activation Shapes the Intestinal Microbiota in Patients with Familial Diarrhea and Increased Susceptibility for Crohn's Disease
Inflamm Bowel Dis, 23 (10), 1752-1761
DOI 10.1097/MIB.0000000000001264, PubMed 28902124

Trøseid M (2017)
Gut microbiota and acute coronary syndromes: ready for use in the emergency room?
Eur Heart J, 38 (11), 825-827
DOI 10.1093/eurheartj/ehx005, PubMed 28159962

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO (2017)
Extracellular matrix markers and risk of myocardial infarction: The HUNT Study in Norway
Eur J Prev Cardiol, 24 (11), 1161-1167
DOI 10.1177/2047487317703826, PubMed 28429960

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO (2017)
Monocyte/macrophage and T cell activation markers are not independently associated with MI risk in healthy individuals - results from the HUNT Study
Int J Cardiol, 243, 502-504
DOI 10.1016/j.ijcard.2017.05.106, PubMed 28615143

Unemo M, Salado-Rasmussen K, Hansen M, Olsen AO, Falk M, Golparian D, Aasterød M, Ringlander J, Nilsson CS, Sundqvist M, Schønning K, Moi H, Westh H, Jensen JS (2017)
Clinical and analytical evaluation of the new Aptima Mycoplasma genitalium assay, with data on M. genitalium prevalence and antimicrobial resistance in M. genitalium in Denmark, Norway and Sweden in 2016
Clin Microbiol Infect, 24 (5), 533-539
DOI 10.1016/j.cmi.2017.09.006, PubMed 28923377

Vehus T, Waaler J, Krauss S, Lundanes E, Wilson SR (2017)
Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery
LC GC Eur., 30 (5), 232-239

Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472

Vikum D, Nordøy I, Torp Andersen C, Fevang B, Line PD, Kolrud FK, Aukrust P, Buanes T (2017)
A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy
Case Rep Infect Dis, 2017, 4173246
DOI 10.1155/2017/4173246, PubMed 29435377

Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J (2017)
Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
BMJ Open Gastroenterol, 4 (1), e000134
DOI 10.1136/bmjgast-2017-000134, PubMed 28761687

Watila MM, Keezer MR, Angwafor SA, Winkler AS, Sander JW (2017)
Health service provision for people with epilepsy in sub-Saharan Africa: A situational review
Epilepsy Behav, 70 (Pt A), 24-32
DOI 10.1016/j.yebeh.2017.03.014, PubMed 28410462

Wei L, Pitaval RA, Corander J, Tirkkonen O (2017)
From Random Matrix Theory to Coding Theory: Volume of a Metric Ball in Unitary Group
IEEE Trans. Inf. Theory, 63 (5), 2814-2821

Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E et al. (2017)
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
Gastroenterology, 152 (8), 1975-1984.e8
DOI 10.1053/j.gastro.2017.02.038, PubMed 28274849

Welsh P, Kou L, Yu C, Anand I, van Veldhuisen DJ, Maggioni AP, Desai AS, Solomon SD, Pfeffer MA, Cheng S, Gullestad L, Aukrust P, Ueland T, Swedberg K, Young JB, Kattan MW, Sattar N, McMurray JJV (2017)
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study
Eur J Heart Fail, 20 (2), 268-277
DOI 10.1002/ejhf.988, PubMed 28960777

Winkler AS, Olsen IT, Gradmann C (2017)
Global health and its changing landscape
Tidsskr Nor Laegeforen, 137 (12-13), 853
DOI 10.4045/tidsskr.17.0489, PubMed 28655223

Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T et al. (2017)
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827

Xing M, Bjørås M, Daniel JA, Alt FW, Oksenych V (2017)
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70
DNA Repair (Amst), 57, 133-138
DOI 10.1016/j.dnarep.2017.07.008, PubMed 28759779

Yardley M, Ueland T, Aukrust P, Michelsen A, Bjørkelund E, Gullestad L, Nytrøen K (2017)
Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients
Open Heart, 4 (2), e000635
DOI 10.1136/openhrt-2017-000635, PubMed 29225901

Yimer SA, Birhanu AG, Kalayou S, Riaz T, Zegeye ED, Beyene GT, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2017)
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
Front Microbiol, 8, 795
DOI 10.3389/fmicb.2017.00795, PubMed 28536560

Zheng Z, Wei L, Speicher R, Muller RR, Hamalainen J, Corander J (2017)
Asymptotic Analysis of Rayleigh Product Channels: A Free Probability Approach
IEEE Trans. Inf. Theory, 63 (3), 1731-1745

Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
G3 (Bethesda), 7 (6), 1753-1766
DOI 10.1534/g3.117.042317, PubMed 28428242

Zimmermann C, Santos A, Gable K, Epstein S, Gururaj C, Chymkowitch P, Pultz D, Rødkær SV, Clay L, Bjørås M, Barral Y, Chang A, Færgeman NJ, Dunn TM, Riezman H, Enserink JM (2017)
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy
Cell Rep, 18 (8), 2073-2074
DOI 10.1016/j.celrep.2017.02.020, PubMed 28228270

Publications 2016

Aanensen DM, Feil EJ, Holden MT, Dordel J, Yeats CA, Fedosejev A, Goater R, Castillo-Ramírez S, Corander J, Colijn C, Chlebowicz MA, Schouls L, Heck M, Pluister G, Ruimy R, Kahlmeter G, Åhman J, Matuschek E, Friedrich AW, Parkhill J, Bentley SD, Spratt BG, Grundmann H, European SRL Working Group (2016)
Whole-Genome Sequencing for Routine Pathogen Surveillance in Public Health: a Population Snapshot of Invasive Staphylococcus aureus in Europe
mBio, 7 (3)
DOI 10.1128/mBio.00444-16, PubMed 27150362

Ahmed A, Hollan I, Curran SA, Kitson SM, Riggio MP, Mikkelsen K, Almdahl SM, Aukrust P, McInnes IB, Goodyear CS (2016)
Brief Report: Proatherogenic Cytokine Microenvironment in the Aortic Adventitia of Patients With Rheumatoid Arthritis
Arthritis Rheumatol, 68 (6), 1361-6
DOI 10.1002/art.39574, PubMed 26749303

Andersen KM, Kristoffersen AK, Ingebretsen A, Vikholt KJ, Örtengren UT, Olsen I, Enersen M, Gaustad P (2016)
Diversity and antifungal susceptibility of Norwegian Candida glabrata clinical isolates
J Oral Microbiol, 8, 29849
DOI 10.3402/jom.v8.29849, PubMed 26861194

Arain F, Gullestad L, Nymo S, Kjekshus J, Cleland JG, Michelsen A, McMurray JJ, Wikstrand J, Aukrust P, Ueland T (2016)
Low YKL-40 in chronic heart failure may predict beneficial effects of statins: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA)
Biomarkers, 22 (3-4), 261-267
DOI 10.1080/1354750X.2016.1204003, PubMed 27325138

Aresvik DM, Lima K, Øverland T, Mollnes TE, Abrahamsen TG (2016)
Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
Scand J Immunol, 83 (3), 188-94
DOI 10.1111/sji.12406, PubMed 26708691

Åsberg A, Humar A, Rollag H, Jardine AG, Kumar D, Aukrust P, Ueland T, Bignamini AA, Hartmann A (2016)
Lessons Learned From a Randomized Study of Oral Valganciclovir Versus Parenteral Ganciclovir Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: The VICTOR Trial
Clin Infect Dis, 62 (9), 1154-60
DOI 10.1093/cid/ciw084, PubMed 26908810

Barbé B, Verdonck K, Mukendi D, Lejon V, Lilo Kalo JR, Alirol E, Gillet P, Horié N, Ravinetto R, Bottieau E, Yansouni C, Winkler AS, van Loen H, Boelaert M, Lutumba P, Jacobs J (2016)
The Art of Writing and Implementing Standard Operating Procedures (SOPs) for Laboratories in Low-Resource Settings: Review of Guidelines and Best Practices
PLoS Negl Trop Dis, 10 (11), e0005053
DOI 10.1371/journal.pntd.0005053, PubMed 27812100

Benterud T, Ystgaard MB, Manueldas S, Pankratov L, Alfaro-Cervello C, Florholmen G, Ahmed MS, Sandvik L, Norgren S, Bjørås M, Baumbusch LO, Solberg R, Saugstad OD (2016)
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia
Neonatology, 111 (1), 12-21
DOI 10.1159/000447255, PubMed 27497671

Beres SB, Kachroo P, Nasser W, Olsen RJ, Zhu L, Flores AR, de la Riva I, Paez-Mayorga J, Jimenez FE, Cantu C, Vuopio J, Jalava J, Kristinsson KG, Gottfredsson M, Corander J, Fittipaldi N, Di Luca MC, Petrelli D, Vitali LA, Raiford A, Jenkins L, Musser JM (2016)
Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes
mBio, 7 (3)
DOI 10.1128/mBio.00403-16, PubMed 27247229

Berild D (2016)
An unexpected death?
Tidsskr Nor Laegeforen, 136 (14-15), 1182
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Beyene GT, Balasingham SV, Frye SA, Namouchi A, Homberset H, Kalayou S, Riaz T, Tønjum T (2016)
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Molin SB, De Blasio BF, Olsen AO (2016)
Is the risk for sexually transmissible infections (STI) lower among women with exclusively female sexual partners compared with women with male partners? A retrospective study based on attendees at a Norwegian STI clinic from 2004 to 2014
Sex Health, 13 (3), 257-64
DOI 10.1071/SH15193, PubMed 27050292

Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2016)
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849

Namouchi A, Gómez-Muñoz M, Frye SA, Moen LV, Rognes T, Tønjum T, Balasingham SV (2016)
The Mycobacterium tuberculosis transcriptional landscape under genotoxic stress
BMC Genomics, 17 (1), 791
DOI 10.1186/s12864-016-3132-1, PubMed 27724857

Nawaz MS, Vik ES, Berges N, Fladeby C, Bjørås M, Dalhus B, Alseth I (2016)
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
J Biol Chem, 291 (41), 21786-21801
DOI 10.1074/jbc.M116.730911, PubMed 27573237

Nawaz MS, Vik ES, Ronander ME, Solvoll AM, Blicher P, Bjørås M, Alseth I, Dalhus B (2016)
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease
Sci Rep, 6, 24979
DOI 10.1038/srep24979, PubMed 27108838

Nilsen E, Aasterød M, Hustad PS, Olsen AO (2016)
Mecillinam against genital Chlamydia trachomatis infection: a small-scale proof-of-concept study shows a low cure rate
J Antimicrob Chemother, 71 (8), 2270-2
DOI 10.1093/jac/dkw134, PubMed 27165786

Niyonzima N, Halvorsen B, Sporsheim B, Garred P, Aukrust P, Mollnes TE, Espevik T (2016)
Complement activation by cholesterol crystals triggers a subsequent cytokine response
Mol Immunol, 84, 43-50
DOI 10.1016/j.molimm.2016.09.019, PubMed 27692470

Norum HM, Kolberg ES, Solhaug V, Nordal K, Aukrust P (2016)
Rhabdomyolysis and capillary leak syndrome in a patient treated with topical imiquimod
Int J Dermatol, 55 (9), 1030-2
DOI 10.1111/ijd.13255, PubMed 27061736

Numminen E, Chewapreecha C, Turner C, Goldblatt D, Nosten F, Bentley SD, Turner P, Corander J (2016)
Corrigendum: Climate induces seasonality in pneumococcal transmission
Sci Rep, 6, 23307
DOI 10.1038/srep23307, PubMed 27022945

Numminen E, Gutmann M, Shubin M, Marttinen P, Méric G, van Schaik W, Coque TM, Baquero F, Willems RJ, Sheppard SK, Feil EJ, Hanage WP, Corander J (2016)
The impact of host metapopulation structure on the population genetics of colonizing bacteria
J Theor Biol, 396, 53-62
DOI 10.1016/j.jtbi.2016.02.019, PubMed 26916623

Otterdal K, Portillo A, Astrup E, Ludviksen J, Davì G, Holm S, Santilli F, Vitale G, Raoult D, Olano JP, Schjalm C, Halvorsen B, Oteo JA, Mollnes TE, Aukrust P, Nilsson PH (2016)
High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
Cytokine, 83, 269-274
DOI 10.1016/j.cyto.2016.05.006, PubMed 27180202

Otterdal K, Portillo A, Astrup E, Ludviksen JK, Schjalm C, Raoult D, Olano JP, Halvorsen B, Oteo JA, Aukrust P, Mollnes TE, Nilsson PH (2016)
Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
Clin Microbiol Infect, 22 (8), 734.e1-6
DOI 10.1016/j.cmi.2016.05.010, PubMed 27217049

Palibrk V, Suganthan R, Scheffler K, Wang W, Bjørås M, Bøe SO (2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic-ischemic encephalopathy model
Cell Death Dis, 7 (7), e2320
DOI 10.1038/cddis.2016.223, PubMed 27468695

Palm Ø, Ueland T, Garen T, Michelsen AE, Reiseter S, Aukrust P, Aaløkken TM, Molberg Ø (2016)
Endostatin is higher and associated with pulmonary involvement in primary Sjögren's syndrome
Clin Exp Rheumatol, 34 (4), 690-3
PubMed 27214260

Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A (2016)
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962

Petrova L, Gran C, Bjoras M, Doetsch PW (2016)
Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells
PLoS One, 11 (6), e0158581
DOI 10.1371/journal.pone.0158581, PubMed 27362559

Pilely K, Rosbjerg A, Genster N, Gal P, Pál G, Halvorsen B, Holm S, Aukrust P, Bakke SS, Sporsheim B, Nervik I, Niyonzima N, Bartels ED, Stahl GL, Mollnes TE, Espevik T, Garred P (2016)
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
J Immunol, 196 (12), 5064-74
DOI 10.4049/jimmunol.1502595, PubMed 27183610

Pitaval RA, Wei L, Tirkkonen O, Corander J (2016)
Volume of Metric Balls in High-Dimensional Complex Grassmann Manifolds
IEEE Trans. Inf. Theory, 62 (9), 5105-5116

Prebensen C, Lind A, Dyrhol-Riise AM, Kvale D (2016)
Regulation of Gag- and Env-Specific CD8+ T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy
PLoS One, 11 (4), e0153849
DOI 10.1371/journal.pone.0153849, PubMed 27128502

Roberg-Larsen H, Lund K, Seterdal KE, Solheim S, Vehus T, Solberg N, Krauss S, Lundanes E, Wilson SR (2016)
Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes
J Steroid Biochem Mol Biol, 169, 22-28
DOI 10.1016/j.jsbmb.2016.02.006, PubMed 26877254

Rosenstierne MW, Karlberg H, Bragstad K, Lindegren G, Stoltz ML, Salata C, Kran AM, Dudman SG, Mirazimi A, Fomsgaard A (2016)
Rapid Bedside Inactivation of Ebola Virus for Safe Nucleic Acid Tests
J Clin Microbiol, 54 (10), 2521-9
DOI 10.1128/JCM.00346-16, PubMed 27466385

Saadati HR, Wittig M, Helbig I, Häsler R, Anderson CA, Mathew CG, Kupcinskas L, Parkes M, Karlsen TH, Rosenstiel P, Schreiber S, Franke A (2016)
Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
BMC Med Genet, 17, 26
DOI 10.1186/s12881-016-0289-z, PubMed 27037036

Sankar A, Malone B, Bayliss SC, Pascoe B, Méric G, Hitchings MD, Sheppard SK, Feil EJ, Corander J, Honkela A (2016)
Bayesian identification of bacterial strains from sequencing data
Microb Genom, 2 (8), e000075
DOI 10.1099/mgen.0.000075, PubMed 28348870

Santilli F, Liani R, Di Fulvio P, Formoso G, Simeone P, Tripaldi R, Ueland T, Aukrust P, Davì G (2016)
Increased circulating resistin is associated with insulin resistance, oxidative stress and platelet activation in type 2 diabetes mellitus
Thromb Haemost, 116 (6), 1089-1099
DOI 10.1160/TH16-06-0471, PubMed 27709225

Schmidt V, Kositz C, Herbinger KH, Carabin H, Ngowi B, Naman E, Wilkins PP, Noh J, Matuja W, Winkler AS (2016)
Association between Taenia solium infection and HIV/AIDS in northern Tanzania: a matched cross sectional-study
Infect Dis Poverty, 5 (1), 111
DOI 10.1186/s40249-016-0209-7, PubMed 27903304

Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2016)
The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
J Hepatol, 66 (2), 382-389
DOI 10.1016/j.jhep.2016.09.020, PubMed 27720803

Schuermann D, Scheidegger SP, Weber AR, Bjørås M, Leumann CJ, Schär P (2016)
3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair
Nucleic Acids Res, 44 (5), 2187-98
DOI 10.1093/nar/gkv1520, PubMed 26733580

Shubin M, Schaufler K, Tedin K, Vehkala M, Corander J (2016)
Identifying Multiple Potential Metabolic Cycles in Time-Series from Biolog Experiments
PLoS One, 11 (9), e0162276
DOI 10.1371/journal.pone.0162276, PubMed 27676629

Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Neto EC et al. (2016)
Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Nat Commun, 7, 13205
DOI 10.1038/ncomms13205, PubMed 27721464

Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Neto EC et al. (2016)
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Nat Commun, 7, 12460
DOI 10.1038/ncomms12460, PubMed 27549343

Siljan WW, Holter JC, Nymo SH, Schjalm C, Müller F, Jenum PA, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2016)
Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome
J Infect, 73 (4), 383-6
DOI 10.1016/j.jinf.2016.07.011, PubMed 27452197

Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510

Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B (2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A et al. (2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939

Sokolova M, Vinge LE, Alfsnes K, Olsen MB, Eide L, Kaasbøll OJ, Attramadal H, Torp MK, Fosshaug LE, Rashidi A, Lien E, Finsen AV, Sandanger Ø, Aukrust P, Ranheim T, Yndestad A (2016)
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Biochim Biophys Acta Mol Cell Biol Lipids, 1862 (2), 234-245
DOI 10.1016/j.bbalip.2016.11.003, PubMed 27845246

Sorte HS, Osnes LT, Fevang B, Aukrust P, Erichsen HC, Backe PH, Abrahamsen TG, Kittang OB, Øverland T, Jhangiani SN, Muzny DM, Vigeland MD, Samarakoon P, Gambin T, Akdemir ZH, Gibbs RA, Rødningen OK, Lyle R, Lupski JR, Stray-Pedersen A (2016)
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283

Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
J Acquir Immune Defic Syndr, 73 (2), 138-48
DOI 10.1097/QAI.0000000000001080, PubMed 27632144

Storz C, Schutz C, Tluway A, Matuja W, Schmutzhard E, Winkler AS (2016)
Clinical findings and management of patients with meningitis with an emphasis on Haemophilus influenzae meningitis in rural Tanzania
J Neurol Sci, 366, 52-58
DOI 10.1016/j.jns.2016.04.044, PubMed 27288776

Stray-Pedersen A, Sorte HS, Samarakoon P, Gambin T, Chinn IK, Coban Akdemir ZH, Erichsen HC, Forbes LR, Gu S, Yuan B, Jhangiani SN, Muzny DM, Rødningen OK, Sheng Y, Nicholas SK, Noroski LM, Seeborg FO, Davis CM, Canter DL, Mace EM, Vece TJ, Allen CE, Abhyankar HA, Boone PM, Beck CR et al. (2016)
Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders
J Allergy Clin Immunol, 139 (1), 232-245
DOI 10.1016/j.jaci.2016.05.042, PubMed 27577878

Stylianou E, Ueland T, Borchsenius F, Michelsen AE, Øvstebø R, Mollnes TE, Skjønsberg OH, Aukrust P (2016)
Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
Scand J Clin Lab Invest, 76 (2), 118-27
DOI 10.3109/00365513.2015.1110856, PubMed 26878875

Szilvay AM, Sarria SV, Mannelqvist M, Aasland R, Furnes C (2016)
Proteolytic activity assayed by subcellular localization switching of a substrate
Biochem Biophys Rep, 8, 23-28
DOI 10.1016/j.bbrep.2016.07.011, PubMed 28955937

Taraldsrud E, Aukrust P, Jørgensen S, Lingjærde OC, Olweus J, Myklebust JH, Fevang B (2016)
Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
Clin Immunol, 175, 69-74
DOI 10.1016/j.clim.2016.11.014, PubMed 27919819

Taxt AM, Diaz Y, Aasland R, Clements JD, Nataro JP, Sommerfelt H, Puntervoll P (2016)
Towards Rational Design of a Toxoid Vaccine against the Heat-Stable Toxin of Escherichia coli
Infect Immun, 84 (4), 1239-1249
DOI 10.1128/IAI.01225-15, PubMed 26883587

Tonby K, Wergeland I, Lieske NV, Kvale D, Tasken K, Dyrhol-Riise AM (2016)
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
BMC Infect Dis, 16 (1), 599
DOI 10.1186/s12879-016-1938-8, PubMed 27776487

Trevisan C, Devleesschauwer B, Schmidt V, Winkler AS, Harrison W, Johansen MV (2016)
The societal cost of Taenia solium cysticercosis in Tanzania
Acta Trop, 165, 141-154
DOI 10.1016/j.actatropica.2015.12.021, PubMed 26756713

Trøseid M, Hov JR, Nestvold TK, Thoresen H, Berge RK, Svardal A, Lappegård KT (2016)
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
Metab Syndr Relat Disord, 14 (4), 197-201
DOI 10.1089/met.2015.0120, PubMed 27081744

Vehus T, Roberg-Larsen H, Waaler J, Aslaksen S, Krauss S, Wilson SR, Lundanes E (2016)
Versatile, sensitive liquid chromatography mass spectrometry - Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins
Sci Rep, 6, 37507
DOI 10.1038/srep37507, PubMed 27897190

Vehus T, Seterdal KE, Krauss S, Lundanes E, Wilson SR (2016)
Comparison of commercial nanoliquid chromatography columns for fast, targeted mass spectrometry-based proteomics
Future Sci OA, 2 (2), FSO119
DOI 10.4155/fsoa-2016-0014, PubMed 28031966

Waagsbø B, Svardal A, Ueland T, Landrø L, Øktedalen O, Berge RK, Flo TH, Aukrust P, Damås JK (2016)
Low levels of short- and medium-chain acylcarnitines in HIV-infected patients
Eur J Clin Invest, 46 (5), 408-17
DOI 10.1111/eci.12609, PubMed 26913383

Wang J, Thingholm LB, Skiecevičienė J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P et al. (2016)
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Nat Genet, 48 (11), 1396-1406
DOI 10.1038/ng.3695, PubMed 27723756

Wergeland I, Assmus J, Dyrhol-Riise AM (2016)
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
PLoS One, 11 (9), e0163848
DOI 10.1371/journal.pone.0163848, PubMed 27685462

Yang ZR, Corander J, Oja E (2016)
Low-Rank Doubly Stochastic Matrix Decomposition for Cluster Analysis
J. Mach. Learn. Res., 17, 187

Yimer SA, Namouchi A, Zegeye ED, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2016)
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
BMC Evol Biol, 16 (1), 146
DOI 10.1186/s12862-016-0715-z, PubMed 27363525

Yndestad A, Sandanger Ø, Jong WMC, Aukrust P, Zuurbier CJ (2016)
Response to letter from Toldo et al. on "NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective"
Biochem Biophys Res Commun, 474 (2), 328-329
DOI 10.1016/j.bbrc.2016.04.096, PubMed 27109473

Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH et al. (2016)
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
JAMA Neurol, 73 (6), 691-7
DOI 10.1001/jamaneurol.2016.0150, PubMed 27088644

Zandi H, Rodrigues RC, Kristoffersen AK, Enersen M, Mdala I, Ørstavik D, Rôças IN, Siqueira JF (2016)
Antibacterial Effectiveness of 2 Root Canal Irrigants in Root-filled Teeth with Infection: A Randomized Clinical Trial
J Endod, 42 (9), 1307-13
DOI 10.1016/j.joen.2016.06.006, PubMed 27452293

Zegeye N, Asrat D, Woldeamanuel Y, Habte A, Gedlu E, Tønjum T, Aseffa A (2016)
Throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease
BMC Infect Dis, 16 (1), 510
DOI 10.1186/s12879-016-1841-3, PubMed 27663649

Zenouzi R, Weismüller TJ, Jørgensen KK, Bubenheim M, Lenzen H, Hübener P, Schulze K, Weiler-Normann C, Sebode M, Ehlken H, Pannicke N, Hartl J, Peiseler M, Hübener S, Karlsen TH, Boberg KM, Manns MP, Lohse AW, Schramm C (2016)
No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
Clin Gastroenterol Hepatol, 14 (12), 1806-1812
DOI 10.1016/j.cgh.2016.07.032, PubMed 27521513

Zweers SJ, Shiryaev A, Komuta M, Vesterhus M, Hov JR, Perugorria MJ, de Waart DR, Chang JC, Tol S, Te Velde AA, de Jonge WJ, Banales JM, Roskams T, Beuers U, Karlsen TH, Jansen PL, Schaap FG (2016)
Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis
Liver Int, 36 (9), 1370-7
DOI 10.1111/liv.13092, PubMed 26866350

Publications 2015

Abbas A, Gregersen I, Holm S, Daissormont I, Bjerkeli V, Krohg-Sørensen K, Skagen KR, Dahl TB, Russell D, Almås T, Bundgaard D, Alteheld LH, Rashidi A, Dahl CP, Michelsen AE, Biessen EA, Aukrust P, Halvorsen B, Skjelland M (2015)
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806

Åberg F, Gissler M, Karlsen TH, Ericzon BG, Foss A, Rasmussen A, Bennet W, Olausson M, Line PD, Nordin A, Bergquist A, Boberg KM, Castedal M, Pedersen CR, Isoniemi H (2015)
Differences in long-term survival among liver transplant recipients and the general population: a population-based Nordic study
Hepatology, 61 (2), 668-77
DOI 10.1002/hep.27538, PubMed 25266201

Andersen IM, Fosby B, Boberg KM, Clausen OP, Jebsen P, Melum E, Line PD, Foss A, Schrumpf E, Karlsen TH (2015)
Indications and Outcomes in Liver Transplantation in Patients With Primary Sclerosing Cholangitis in Norway
Transplant Direct, 1 (9), e39
DOI 10.1097/TXD.0000000000000548, PubMed 27500239

Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331

Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426

Anonsen JH, Vik Å, Børud B, Viburiene R, Aas FE, Kidd SW, Aspholm M, Koomey M (2015)
Characterization of a Unique Tetrasaccharide and Distinct Glycoproteome in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica
J Bacteriol, 198 (2), 256-67
DOI 10.1128/JB.00620-15, PubMed 26483525

Arora S, Andreassen AK, Andersson B, Gustafsson F, Eiskjaer H, Bøtker HE, Rådegran G, Gude E, Ioanes D, Solbu D, Sigurdardottir V, Dellgren G, Erikstad I, Solberg OG, Ueland T, Aukrust P, Gullestad L, SCHEDULE (SCandinavian HEart transplant everolimus De novo stUdy with earLy calcineurin inhibitors avoidancE) Investigators (2015)
The Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Recipients: One-Year Results of a Scandinavian Randomized Trial
Am J Transplant, 15 (7), 1967-75
DOI 10.1111/ajt.13214, PubMed 25783974

Askevold ET, Gullestad L, Nymo S, Kjekshus J, Yndestad A, Latini R, Cleland JG, McMurray JJ, Aukrust P, Ueland T (2015)
Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
PLoS One, 10 (8), e0133970
DOI 10.1371/journal.pone.0133970, PubMed 26288364

Baig A, McNally A, Dunn S, Paszkiewicz KH, Corander J, Manning G (2015)
Genetic import and phenotype specific alleles associated with hyper-invasion in Campylobacter jejuni
BMC Genomics, 16, 852
DOI 10.1186/s12864-015-2087-y, PubMed 26497129

Berg A, Otterdal K, Patel S, Gonca M, David C, Dalen I, Nymo S, Nilsson M, Nordling S, Magnusson PU, Ueland T, Prato M, Giribaldi G, Mollnes TE, Aukrust P, Langeland N, Nilsson PH (2015)
Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria
J Infect Dis, 212 (11), 1835-40
DOI 10.1093/infdis/jiv283, PubMed 25980034

Berild D (2015)
[An unusual cause of back pain]
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