Rafael Romero-Becerra

  • Postdoc researcher; PhD

Interested in drug combination therapies and biomarker identification. Experienced in in vivo data analysis, statistical modeling, and bioinformatics. Expertise in mixed-effects modeling, R package and Shiny app development, and omics data analysis (phospho/proteomics, transcriptomics, scRNA-Seq). Background in biochemistry, molecular biomedicine, and biostatistics.

Profile and publications from Google Scholar

 

Publications 2025

Cicuéndez B, Mora A, López JA, Curtabbi A, Pérez-García J, Porteiro B, Jimenez-Blasco D, Latorre-Muro P, Vo P, Jerome M, Gómez-Santos B, Romero-Becerra R, Leiva M, Rodríguez E, León M, Leiva-Vega L, Gómez-Lado N, Torres JL, Hernández-Cosido L, Aguiar P, Marcos M, Jastroch M, Daiber A, Aspichueta P, Bolaños JP et al. (2025)
Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis
Nat Commun, 16 (1), 229
DOI 10.1038/s41467-024-54353-4, PubMed 39805849

Publications 2024

Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G (2024)
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis
EMBO Rep, 25 (6), 2635-2661
DOI 10.1038/s44319-024-00149-y, PubMed 38730210

Publications 2023

Romero-Becerra R, Cruz FM, Mora A, Lopez JA, Ponce-Balbuena D, Allan A, Ramos-Mondragón R, González-Terán B, León M, Rodríguez ME, Leiva-Vega L, Guerrero-Serna G, Jimenez-Vazquez EN, Filgueiras-Rama D, Vázquez J, Jalife J, Sabio G (2023)
p38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmia
Nat Cardiovasc Res, 2 (12), 1204-1220
DOI 10.1038/s44161-023-00368-x, PubMed 39196141

Publications 2022

Loza-Valdes A, El-Merahbi R, Kassouf T, Demczuk A, Reuter S, Viera JT, Karwen T, Noh M, Löffler MC, Romero-Becerra R, Torres JL, Marcos M, Sabio G, Wojda U, Sumara G (2022)
Targeting ERK3/MK5 complex for treatment of obesity and diabetes
Biochem Biophys Res Commun, 612, 119-125
DOI 10.1016/j.bbrc.2022.04.070, PubMed 35523049

Romero-Becerra R, Mora A, Manieri E, Nikolic I, Santamans AM, Montalvo-Romeral V, Cruz FM, Rodríguez E, León M, Leiva-Vega L, Sanz L, Bondía V, Filgueiras-Rama D, Jiménez-Borreguero LJ, Jalife J, Gonzalez-Teran B, Sabio G (2022)
MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation
Elife, 11
DOI 10.7554/eLife.75250, PubMed 35971771

Publications 2020

Romero-Becerra R, Santamans AM, Folgueira C, Sabio G (2020)
p38 MAPK Pathway in the Heart: New Insights in Health and Disease
Int J Mol Sci, 21 (19)
DOI 10.3390/ijms21197412, PubMed 33049962

Publications 2019

Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J et al. (2019)
p38γ is essential for cell cycle progression and liver tumorigenesis
Nature, 568 (7753), 557-560
DOI 10.1038/s41586-019-1112-8, PubMed 30971822

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