Publications Flatmark Group

Publications published since 1999 from OUS - Translational Cancer Therapy

283 publications found

Publications 2019

  1. Abrahamsson H, Porojnicu AC, Lindstrøm JC, Dueland S, Flatmark K, Hole KH, Seierstad T, Moan J, Redalen KR, Meltzer S, Ree AH (2019)
    High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
    BMC Cancer, 19 (1), 488
    DOI 10.1186/s12885-019-5724-z, PubMed 31122213
  2. Aghayan DL, Fretland ÅA, Kazaryan AM, Sahakyan MA, Dagenborg VJ, Bjørnbeth BA, Flatmark K, Kristiansen R, Edwin B (2019)
    Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
    HPB (Oxford), 21 (11), 1485-1490
    DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136
  3. Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland ÅA, Røsok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjørnbeth BA, Vauthey JN (2019)
    RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
    Ann Surg, 269 (1), 120-126
    DOI 10.1097/SLA.0000000000002319, PubMed 28549012
  4. Calvete J, Larrinaga G, Errarte P, Martín AM, Dotor A, Esquinas C, Nunes-Xavier CE, Pulido R, López JI, Angulo JC (2019)
    The coexpression of fibroblast activation protein (FAP) and basal-type markers (CK 5/6 and CD44) predicts prognosis in high-grade invasive urothelial carcinoma of the bladder
    Hum Pathol, 91, 61-68
    DOI 10.1016/j.humpath.2019.07.002, PubMed 31279874
  5. Flem-Karlsen K, Fodstad Y, Nunes-Xavier CE (2019)
    B7-H3 immune checkpoint protein in human cancer
    Curr Med Chem (in press)
    DOI 10.2174/0929867326666190517115515, PubMed 31099317
  6. Flem-Karlsen K, Tekle C, Øyjord T, Flørenes VA, Mælandsmo GM, Fodstad Ø, Nunes-Xavier CE (2019)
    p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
    Sci Rep, 9 (1), 5839
    DOI 10.1038/s41598-019-42303-w, PubMed 30967582
  7. Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
    A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
    Transl Oncol, 12 (7), 951-958
    DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111
  8. Fretland ÅA, Dagenborg VJ, Waaler Bjørnelv GM, Aghayan DL, Kazaryan AM, Barkhatov L, Kristiansen R, Fagerland MW, Edwin B, Andersen MH (2019)
    Quality of life from a randomized trial of laparoscopic or open liver resection for colorectal liver metastases
    Br J Surg, 106 (10), 1372-1380
    DOI 10.1002/bjs.11227, PubMed 31322735
  9. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2019)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gkz885, PubMed 31598695
  10. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2019)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gkz1016, PubMed 31642479
  11. Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2019)
    ImmunoPeCa trial: Long-term outcome following intraperitoneal MOC31PE immunotoxin treatment in colorectal peritoneal metastasis
    Eur J Surg Oncol (in press)
    DOI 10.1016/j.ejso.2019.04.014, PubMed 31036394
  12. Hansen EP, Fromm B, Andersen SD, Marcilla A, Andersen KL, Borup A, Williams AR, Jex AR, Gasser RB, Young ND, Hall RS, Stensballe A, Ovchinnikov V, Yan Y, Fredholm M, Thamsborg SM, Nejsum P (2019)
    Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk
    J Extracell Vesicles, 8 (1), 1578116
    DOI 10.1080/20013078.2019.1578116, PubMed 30815237
  13. Hausken J, Fretland ÅA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW, Kristiansen R, Røysland K, Kvarstein G, Tønnessen TI (2019)
    Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
    Ann Surg, 270 (2), 193-199
    DOI 10.1097/SLA.0000000000003209, PubMed 30676382
  14. Johansen R, Andersson Y (2019)
    Generic substitution of drugs in hospitals
    Tidsskr Nor Laegeforen, 139 (1)
    DOI 10.4045/tidsskr.17.0722, PubMed 30644679
  15. Lode HE, Gjølberg TT, Foss S, Sivertsen MS, Brustugun J, Andersson Y, Jørstad ØK, Moe MC, Andersen JT (2019)
    A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
    Sci Rep, 9 (1), 18021
    DOI 10.1038/s41598-019-54226-7, PubMed 31792234
  16. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
    Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
    Cold Spring Harb Mol Case Stud, 5 (2)
    DOI 10.1101/mcs.a003566, PubMed 30862609
  17. Meltzer S, Bjørnetrø T, Lyckander LG, Flatmark K, Dueland S, Samiappan R, Johansen C, Kalanxhi E, Ree AH, Redalen KR (2019)
    Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
    Transl Oncol, 12 (8), 1038-1044
    DOI 10.1016/j.tranon.2019.04.014, PubMed 31146167
  18. Mingo J, Luna S, Gaafar A, Nunes-Xavier CE, Torices L, Mosteiro L, Ruiz R, Guerra I, Llarena R, Angulo JC, López JI, Pulido R (2019)
    Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology
    NPJ Precis Oncol, 3, 11
    DOI 10.1038/s41698-019-0083-4, PubMed 30993208
  19. Nunes-Xavier CE, Angulo JC, Pulido R, López JI (2019)
    A Critical Insight into the Clinical Translation of PD-1/PD-L1 Blockade Therapy in Clear Cell Renal Cell Carcinoma
    Curr Urol Rep, 20 (1), 1
    DOI 10.1007/s11934-019-0866-8, PubMed 30645700
  20. Nunes-Xavier CE, Zaldumbide L, Aurtenetxe O, López-Almaraz R, López JI, Pulido R (2019)
    Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
    Int J Mol Sci, 20 (5)
    DOI 10.3390/ijms20051170, PubMed 30866462
  21. Pulido R, Mingo J, Gaafar A, Nunes-Xavier CE, Luna S, Torices L, Angulo JC, López JI (2019)
    Precise Immunodetection of PTEN Protein in Human Neoplasia
    Cold Spring Harb Perspect Med, 9 (12)
    DOI 10.1101/cshperspect.a036293, PubMed 31501265
  22. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
  23. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2019)
    Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
    Clin Exp Metastasis, 36 (6), 511-518
    DOI 10.1007/s10585-019-09991-0, PubMed 31541325

Publications 2018

  1. Aurtenetxe O, Zaldumbide L, Erramuzpe A, López R, López JI, Cortés JM, Pulido R, Nunes-Xavier CE (2018)
    DUSP5 expression associates with poor prognosis in human neuroblastoma
    Exp Mol Pathol, 105 (3), 272-278
    DOI 10.1016/j.yexmp.2018.08.008, PubMed 30171833
  2. Bousquet PA, Meltzer S, Sønstevold L, Esbensen Y, Dueland S, Flatmark K, Sitter B, Bathen TF, Seierstad T, Redalen KR, Eide L, Ree AH (2018)
    Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
    Transl Oncol, 12 (1), 76-83
    DOI 10.1016/j.tranon.2018.09.010, PubMed 30273860
  3. Bråte J, Neumann RS, Fromm B, Haraldsen AAB, Tarver JE, Suga H, Donoghue PCJ, Peterson KJ, Ruiz-Trillo I, Grini PE, Shalchian-Tabrizi K (2018)
    Unicellular Origin of the Animal MicroRNA Machinery
    Curr Biol, 28 (20), 3288-3295.e5
    DOI 10.1016/j.cub.2018.08.018, PubMed 30318349
  4. Flem-Karlsen K, Fodstad Ø, Tan M, Nunes-Xavier CE (2018)
    B7-H3 in Cancer - Beyond Immune Regulation
    Trends Cancer, 4 (6), 401-404
    DOI 10.1016/j.trecan.2018.03.010, PubMed 29860983
  5. Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
    Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
    Ann Surg, 267 (2), 199-207
    DOI 10.1097/SLA.0000000000002353, PubMed 28657937
  6. Fromm B, Kang W, Rovira C, Cayota A, Witwer K, Friedländer MR, Tosar JP (2018)
    Plant microRNAs in human sera are likely contaminants
    J Nutr Biochem, 65, 139-140
    DOI 10.1016/j.jnutbio.2018.07.019, PubMed 30266285
  7. Fromm B, Tosar JP, Lu Y, Halushka MK, Witwer KW (2018)
    Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk
    J Nutr, 148 (9), 1506-1507
    DOI 10.1093/jn/nxy144, PubMed 30184228
  8. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  9. Halushka MK, Fromm B, Peterson KJ, McCall MN (2018)
    Big Strides in Cellular MicroRNA Expression
    Trends Genet, 34 (3), 165-167
    DOI 10.1016/j.tig.2017.12.015, PubMed 29361313
  10. Kalanxhi E, Meltzer S, Schou JV, Larsen FO, Dueland S, Flatmark K, Jensen BV, Hole KH, Seierstad T, Redalen KR, Nielsen DL, Ree AH (2018)
    Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
    Br J Cancer, 118 (10), 1322-1328
    DOI 10.1038/s41416-018-0085-y, PubMed 29695770
  11. Mariathasan AB, Boye K, Giercksky KE, Brennhovd B, Gullestad HP, Emblemsvåg HL, Grøholt KK, Dueland S, Flatmark K, Larsen SG (2018)
    Beyond total mesorectal excision in locally advanced rectal cancer with organ or pelvic side-wall involvement
    Eur J Surg Oncol, 44 (8), 1226-1232
    DOI 10.1016/j.ejso.2018.03.029, PubMed 29691115
  12. Mikalsen SG, Mikalsen LTG, Sandvik JA, Aarnes EK, Fenne S, Flatmark K, Lyng H, Edin NFJ, Pettersen EO (2018)
    Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model
    Acta Oncol, 57 (9), 1216-1224
    DOI 10.1080/0284186X.2018.1457223, PubMed 29630428
  13. Nunes-Xavier CE, Mingo J, López JI, Pulido R (2018)
    The role of protein tyrosine phosphatases in prostate cancer biology
    Biochim Biophys Acta Mol Cell Res, 1866 (1), 102-113
    DOI 10.1016/j.bbamcr.2018.06.016, PubMed 30401533
  14. Saeednejad Zanjani L, Madjd Z, Abolhasani M, Rasti A, Shariftabrizi A, Mehrazma M, Fodstad Ø, Asgari M (2018)
    Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma
    Pathology, 51 (1), 21-31
    DOI 10.1016/j.pathol.2018.08.019, PubMed 30466948
  15. Spasojevic M, Mariathasan AB, Goscinski M, Thorgersen EB, Solbakken AM, Gullestad HP, Ryder T, Flatmark K, Larsen SG (2018)
    Vertical Rectus Abdominis Musculocutaneous Flap Repair Improves Perineal Wound Healing after Abdominoperineal Resection for Irradiated Locally Advanced Rectal Cancer
    Ann Surg Oncol, 25 (5), 1357-1365
    DOI 10.1245/s10434-018-6363-3, PubMed 29497909
  16. Tarver JE, Taylor RS, Puttick MN, Lloyd GT, Pett W, Fromm B, Schirrmeister BE, Pisani D, Peterson KJ, Donoghue PCJ (2018)
    Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss
    Genome Biol Evol, 10 (6), 1457-1470
    DOI 10.1093/gbe/evy096, PubMed 29788279

Publications 2017

  1. Andersson Y, Haavardtun SI, Davidson B, Dørum A, Fleten KG, Fodstad Ø, Flatmark K (2017)
    MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
    Oncotarget, 8 (37), 61800-61809
    DOI 10.18632/oncotarget.18694, PubMed 28977905
  2. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
    Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
    BMC Cancer, 17 (1), 406
    DOI 10.1186/s12885-017-3365-7, PubMed 28592327
  3. Bakke KM, Hole KH, Dueland S, Grøholt KK, Flatmark K, Ree AH, Seierstad T, Redalen KR (2017)
    Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival
    Acta Oncol, 56 (6), 813-818
    DOI 10.1080/0284186X.2017.1287951, PubMed 28464745
  4. Egger B, Bachmann L, Fromm B (2017)
    Atp8 is in the ground pattern of flatworm mitochondrial genomes
    BMC Genomics, 18 (1), 414
    DOI 10.1186/s12864-017-3807-2, PubMed 28549457
  5. Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
    The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
    Pathol Oncol Res, 25 (1), 255-262
    DOI 10.1007/s12253-017-0355-7, PubMed 29098521
  6. Flem-Karlsen K, Tekle C, Andersson Y, Flatmark K, Fodstad Ø, Nunes-Xavier CE (2017)
    Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
    Pigment Cell Melanoma Res, 30 (5), 467-476
    DOI 10.1111/pcmr.12599, PubMed 28513992
  7. Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2017)
    Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
    Ann Surg Oncol, 24 (7), 1916-1922
    DOI 10.1245/s10434-017-5814-6, PubMed 28224367
  8. Graudenzi A, Cava C, Bertoli G, Fromm B, Flatmark K, Mauri G, Castiglioni I (2017)
    Pathway-based classification of breast cancer subtypes
    Front Biosci (Landmark Ed), 22, 1697-1712
    DOI 10.2741/4566, PubMed 28410140
  9. Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M (2017)
    Interplay between Immune Checkpoint Proteins and Cellular Metabolism
    Cancer Res, 77 (6), 1245-1249
    DOI 10.1158/0008-5472.CAN-16-1647, PubMed 28246276
  10. Ovchinnikov VY, Mordvinov VA, Fromm B (2017)
    Extreme conservation of miRNA complements in opisthorchiids
    Parasitol Int, 66 (6), 773-776
    DOI 10.1016/j.parint.2017.09.006, PubMed 28916307
  11. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  12. Saeednejad Zanjani L, Madjd Z, Abolhasani M, Andersson Y, Rasti A, Shariftabrizi A, Asgari M (2017)
    Cytoplasmic expression of CD133 stemness marker is associated with tumor aggressiveness in clear cell renal cell carcinoma
    Exp Mol Pathol, 103 (2), 218-228
    DOI 10.1016/j.yexmp.2017.10.001, PubMed 29050853
  13. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
    Gigascience, 6 (7), 1-12
    DOI 10.1093/gigascience/gix032, PubMed 28459977
  14. Umu SU, Langseth H, Bucher-Johannessen C, Fromm B, Keller A, Meese E, Lauritzen M, Leithaug M, Lyle R, Rounge TB (2017)
    A comprehensive profile of circulating RNAs in human serum
    RNA Biol, 15 (2), 242-250
    DOI 10.1080/15476286.2017.1403003, PubMed 29219730
  15. Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø (2017)
    A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
    Exp Cell Res, 352 (2), 218-224
    DOI 10.1016/j.yexcr.2017.02.005, PubMed 28189639
  16. Zanjani LS, Madjd Z, Abolhasani M, Rasti A, Fodstad O, Andersson Y, Asgari M (2017)
    Increased expression of CD44 is associated with more aggressive behavior in clear cell renal cell carcinoma
    Biomark Med, 12 (1), 45-61
    DOI 10.2217/bmm-2017-0142, PubMed 29243496
  17. Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K (2017)
    Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
    Oncotarget, 8 (44), 76290-76304
    DOI 10.18632/oncotarget.19350, PubMed 29100312
  18. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Alonso A, Nunes-Xavier CE, Bayón Y, Pulido R (2016)
    The Extended Family of Protein Tyrosine Phosphatases
    Methods Mol Biol, 1447, 1-23
    DOI 10.1007/978-1-4939-3746-2_1, PubMed 27514797
  2. Bachmann L, Fromm B, Patella de Azambuja L, Boeger WA (2016)
    The mitochondrial genome of the egg-laying flatworm Aglaiogyrodactylus forficulatus (Platyhelminthes: Monogenoidea)
    Parasit Vectors, 9 (1), 285
    DOI 10.1186/s13071-016-1586-2, PubMed 27188228
  3. Boye K, Jacob H, Frikstad KA, Nesland JM, Maelandsmo GM, Dahl O, Nesbakken A, Flatmark K (2016)
    Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
    Cancer Med, 5 (8), 1840-9
    DOI 10.1002/cam4.766, PubMed 27273130
  4. Dueland S, Ree AH, Grøholt KK, Saelen MG, Folkvord S, Hole KH, Seierstad T, Larsen SG, Giercksky KE, Wiig JN, Boye K, Flatmark K (2016)
    Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome
    Clin Oncol (R Coll Radiol), 28 (8), 532-9
    DOI 10.1016/j.clon.2016.01.014, PubMed 26888115
  5. Egeland EV, Flatmark K, Nesland JM, Flørenes VA, Mælandsmo GM, Boye K (2016)
    Expression and clinical significance of Wee1 in colorectal cancer
    Tumour Biol, 37 (9), 12133-12140
    DOI 10.1007/s13277-016-5081-3, PubMed 27220319
  6. Errarte P, Guarch R, Pulido R, Blanco L, Nunes-Xavier CE, Beitia M, Gil J, Angulo JC, López JI, Larrinaga G (2016)
    The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases
    PLoS One, 11 (12), e0169105
    DOI 10.1371/journal.pone.0169105, PubMed 28033421
  7. Flatmark K, Høye E, Fromm B (2016)
    microRNAs as cancer biomarkers
    Scand J Clin Lab Invest Suppl, 245, S80-3
    DOI 10.1080/00365513.2016.1210330, PubMed 27542003
  8. Flatmark K, Saelen MG, Hole KH, Abrahamsen TW, Fleten KG, Hektoen HH, Redalen KR, Seierstad T, Dueland S, Ree AH (2016)
    Individual tumor volume responses to short-course oxaliplatin-containing induction chemotherapy in locally advanced rectal cancer - Targeting the tumor for radiation sensitivity?
    Radiother Oncol, 119 (3), 505-11
    DOI 10.1016/j.radonc.2016.02.020, PubMed 26968754
  9. Fleten KG, Bakke KM, Mælandsmo GM, Abildgaard A, Redalen KR, Flatmark K (2016)
    Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases
    Clin Exp Metastasis, 34 (1), 51-62
    DOI 10.1007/s10585-016-9829-3, PubMed 27812769
  10. Fleten KG, Flørenes VA, Prasmickaite L, Hill O, Sykora J, Mælandsmo GM, Engesæter B (2016)
    hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma
    Cell Death Discov, 2, 16081
    DOI 10.1038/cddiscovery.2016.81, PubMed 28028438
  11. Frøysnes IS, Larsen SG, Spasojevic M, Dueland S, Flatmark K (2016)
    Complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis in Norway: Prognostic factors and oncologic outcome in a national patient cohort
    J Surg Oncol, 114 (2), 222-7
    DOI 10.1002/jso.24290, PubMed 27173150
  12. Hompland I, Bruland ØS, Ubhayasekhera K, Bergquist J, Boye K (2016)
    Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour
    Clin Sarcoma Res, 6, 21
    DOI 10.1186/s13569-016-0062-2, PubMed 27999655
  13. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  14. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
    Br J Cancer, 115 (8), 929-939
    DOI 10.1038/bjc.2016.278, PubMed 27599042
  15. Kalanxhi E, Hektoen HH, Meltzer S, Dueland S, Flatmark K, Ree AH (2016)
    Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
    BMC Cancer, 16, 536
    DOI 10.1186/s12885-016-2601-x, PubMed 27461255
  16. Kalanxhi E, Risberg K, Barua IS, Dueland S, Waagene S, Andersen SN, Pettersen SJ, Lindvall JM, Redalen KR, Flatmark K, Ree AH (2016)
    Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
    Cancer Res Treat, 49 (2), 374-386
    DOI 10.4143/crt.2016.080, PubMed 27488871
  17. Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M (2016)
    Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
    Cancer Res, 76 (8), 2231-42
    DOI 10.1158/0008-5472.CAN-15-1538, PubMed 27197253
  18. Meltzer S, Kalanxhi E, Hektoen HH, Dueland S, Flatmark K, Redalen KR, Ree AH (2016)
    Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
    Oncotarget, 7 (23), 34907-17
    DOI 10.18632/oncotarget.8995, PubMed 27145458
  19. Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, Øyjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad Ø (2016)
    Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
    Oncotarget, 7 (6), 6891-901
    DOI 10.18632/oncotarget.6902, PubMed 26771843
  20. Nunes-Xavier CE, Pulido R (2016)
    Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome
    Methods Mol Biol, 1447, 25-37
    DOI 10.1007/978-1-4939-3746-2_2, PubMed 27514798
  21. Ramalho-Carvalho J, Fromm B, Henrique R, Jerónimo C (2016)
    Deciphering the function of non-coding RNAs in prostate cancer
    Cancer Metastasis Rev, 35 (2), 235-62
    DOI 10.1007/s10555-016-9628-y, PubMed 27221068
  22. Rud AK, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
    Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
    Diagn Pathol, 11 (1), 50
    DOI 10.1186/s13000-016-0504-4, PubMed 27316334
  23. Seip K, Fleten KG, Barkovskaya A, Nygaard V, Haugen MH, Engesæter BØ, Mælandsmo GM, Prasmickaite L (2016)
    Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors
    Oncotarget, 7 (15), 19997-20015
    DOI 10.18632/oncotarget.7671, PubMed 26918352
  24. Thorgersen EB, Goscinski MA, Spasojevic M, Solbakken AM, Mariathasan AB, Boye K, Larsen SG, Flatmark K (2016)
    Deep Pelvic Surgical Site Infection After Radiotherapy and Surgery for Locally Advanced Rectal Cancer
    Ann Surg Oncol, 24 (3), 721-728
    DOI 10.1245/s10434-016-5621-5, PubMed 27766561
  25. Ylla G, Fromm B, Piulachs MD, Belles X (2016)
    The microRNA toolkit of insects
    Sci Rep, 6, 37736
    DOI 10.1038/srep37736, PubMed 27883064

Publications 2015

  1. Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S (2015)
    Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
    Br J Cancer, 113 (11), 1548-55
    DOI 10.1038/bjc.2015.380, PubMed 26554649
  2. Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
    Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
    Clin Exp Metastasis, 32 (8), 755-67
    DOI 10.1007/s10585-015-9742-1, PubMed 26349943
  3. Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
    Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
    Acta Ophthalmol, 93 (1), 59-66
    DOI 10.1111/aos.12462, PubMed 25613126
  4. Eide N, Garred Ø, Beiske K, Fodstad Ø (2015)
    Bilateral uveal melanomas with different gene expression detected with 7 years interval
    Acta Ophthalmol, 94 (1), 99-102
    DOI 10.1111/aos.12857, PubMed 26496992
  5. Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
    Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
    Trials, 16, 73
    DOI 10.1186/s13063-015-0577-5, PubMed 25872027
  6. Fromm B, Trelis M, Hackenberg M, Cantalapiedra F, Bernal D, Marcilla A (2015)
    The revised microRNA complement of Fasciola hepatica reveals a plethora of overlooked microRNAs and evidence for enrichment of immuno-regulatory microRNAs in extracellular vesicles
    Int J Parasitol, 45 (11), 697-702
    DOI 10.1016/j.ijpara.2015.06.002, PubMed 26183562
  7. Hektoen HH, Flatmark K, Andersson Y, Dueland S, Redalen KR, Ree AH (2015)
    Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
    BMC Cancer, 15, 543
    DOI 10.1186/s12885-015-1557-6, PubMed 26205955
  8. Hektoen HH, Ree AH, Redalen KR, Flatmark K (2015)
    Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells
    J Enzyme Inhib Med Chem, 31 (5), 779-86
    DOI 10.3109/14756366.2015.1069286, PubMed 26244271
  9. Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
    Tumour exosome integrins determine organotropic metastasis
    Nature, 527 (7578), 329-35
    DOI 10.1038/nature15756, PubMed 26524530
  10. Prasmickaite L, Berge G, Bettum IJ, Aamdal S, Hansson J, Bastholt L, Øijordsbakken M, Boye K, Mælandsmo GM (2015)
    Evaluation of serum osteopontin level and gene polymorphism as biomarkers: analyses from the Nordic Adjuvant Interferon alpha Melanoma trial
    Cancer Immunol Immunother, 64 (6), 769-76
    DOI 10.1007/s00262-015-1686-4, PubMed 25832001
  11. Redalen KR, Sitter B, Bathen TF, Grøholt KK, Hole KH, Dueland S, Flatmark K, Ree AH, Seierstad T (2015)
    High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer
    Radiother Oncol, 118 (2), 393-8
    DOI 10.1016/j.radonc.2015.11.031, PubMed 26705680
  12. Ree AH, Flatmark K, Saelen MG, Folkvord S, Dueland S, Geisler J, Redalen KR (2015)
    Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: opportunities for signaling-adapted therapies
    Crit Rev Oncol Hematol, 95 (1), 114-24
    DOI 10.1016/j.critrevonc.2015.01.003, PubMed 25624177
  13. Repetto-Llamazares AH, Larsen RH, Patzke S, Fleten KG, Didierlaurent D, Pichard A, Pouget JP, Dahle J (2015)
    Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma
    PLoS One, 10 (6), e0128816
    DOI 10.1371/journal.pone.0128816, PubMed 26066655
  14. Seierstad T, Hole KH, Grøholt KK, Dueland S, Ree AH, Flatmark K, Redalen KR (2015)
    MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer
    Br J Radiol, 88 (1051), 20150097
    DOI 10.1259/bjr.20150097, PubMed 25899892
  15. Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh AP, Carter JE, Scammell JG, Fodstad Ø, Singh S (2015)
    Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
    Br J Cancer, 112 (11), 1772-81
    DOI 10.1038/bjc.2015.154, PubMed 25942396
  16. Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
    The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
    Exp Cell Res, 340 (2), 220-6
    DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184

Publications 2014

  1. Haugen MH, Boye K, Nesland JM, Pettersen SJ, Egeland EV, Tamhane T, Brix K, Maelandsmo GM, Flatmark K (2014)
    High expression of the cysteine proteinase legumain in colorectal cancer - implications for therapeutic targeting
    Eur J Cancer, 51 (1), 9-17
    DOI 10.1016/j.ejca.2014.10.020, PubMed 25466510
  2. Ingebrigtsen VA, Boye K, Nesland JM, Nesbakken A, Flatmark K, Fodstad Ø (2014)
    B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome
    BMC Cancer, 14, 602
    DOI 10.1186/1471-2407-14-602, PubMed 25139714
  3. Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
    Br J Cancer, 110 (8), 2072-80
    DOI 10.1038/bjc.2014.113, PubMed 24577056
  4. Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, Landazuri MO, Görlach A, Flamm H, Kieninger J, Urban G, Weltin A, Singleton DC, Haider S, Buffa FM, Harris AL et al. (2014)
    Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
    J Enzyme Inhib Med Chem, 30 (5), 689-721
    DOI 10.3109/14756366.2014.966704, PubMed 25347767
  5. Ree AH, Saelen MG, Kalanxhi E, Østensen IH, Schee K, Røe K, Abrahamsen TW, Dueland S, Flatmark K (2014)
    Biomarkers of histone deacetylase inhibitor activity in a phase 1 combined-modality study with radiotherapy
    PLoS One, 9 (2), e89750
    DOI 10.1371/journal.pone.0089750, PubMed 24587009
  6. Wiiger MT, Bideli H, Fodstad O, Flatmark K, Andersson Y (2014)
    The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells
    J Ovarian Res, 7, 23
    DOI 10.1186/1757-2215-7-23, PubMed 24528603

Publications 2013

  1. Bruheim S, Sandvold ML, Mælandsmo GM, Fodstad O (2013)
    Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts
    Anticancer Res, 33 (9), 3615-21
    PubMed 24023287
  2. Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M (2013)
    Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)
    J Biol Chem, 288 (13), 9165-76
    DOI 10.1074/jbc.M112.422071, PubMed 23386620
  3. Flatmark K, Guldvik IJ, Svensson H, Fleten KG, Flørenes VA, Reed W, Giercksky KE, Fodstad Ø, Andersson Y (2013)
    Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies
    Int J Cancer, 133 (6), 1497-506
    DOI 10.1002/ijc.28158, PubMed 23494569
  4. Friedman R, Boye K, Flatmark K (2013)
    Molecular modelling and simulations in cancer research
    Biochim Biophys Acta, 1836 (1), 1-14
    DOI 10.1016/j.bbcan.2013.02.001, PubMed 23416097
  5. Haugen MH, Johansen HT, Pettersen SJ, Solberg R, Brix K, Flatmark K, Maelandsmo GM (2013)
    Nuclear legumain activity in colorectal cancer
    PLoS One, 8 (1), e52980
    DOI 10.1371/journal.pone.0052980, PubMed 23326369
  6. Ragnum HB, Røe K, Holm R, Vlatkovic L, Nesland JM, Aarnes EK, Ree AH, Flatmark K, Seierstad T, Lilleby W, Lyng H (2013)
    Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer
    Int J Radiat Oncol Biol Phys, 87 (4), 753-60
    DOI 10.1016/j.ijrobp.2013.07.023, PubMed 24035332
  7. Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    DOI 10.1038/bjc.2013.450, PubMed 23942067
  8. Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
    Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
    PLoS One, 8 (6), e66165
    DOI 10.1371/journal.pone.0066165, PubMed 23824282
  9. Sørensen O, Andersen AM, Kristian A, Giercksky KE, Flatmark K (2013)
    Impact of hyperthermia on pharmacokinetics of intraperitoneal mitomycin C in rats investigated by microdialysis
    J Surg Oncol, 109 (6), 521-6
    DOI 10.1002/jso.23527, PubMed 24347444
  10. Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
    In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
    Exp Hematol Oncol, 2 (1), 16
    DOI 10.1186/2162-3619-2-16, PubMed 23738757
  11. Zhai H, Fesler A, Schee K, Fodstad O, Flatmark K, Ju J (2013)
    Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer
    Clin Colorectal Cancer, 12 (4), 261-6
    DOI 10.1016/j.clcc.2013.06.003, PubMed 24012455

Publications 2012

  1. Boye K, Nesland JM, Sandstad B, Haugland Haugen M, Mælandsmo GM, Flatmark K (2012)
    EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer
    Br J Cancer, 107 (4), 667-74
    DOI 10.1038/bjc.2012.293, PubMed 22782346
  2. Brusegard K, Stavnes HT, Nymoen DA, Flatmark K, Trope CG, Davidson B (2012)
    Rab25 is overexpressed in Müllerian serous carcinoma compared to malignant mesothelioma
    Virchows Arch, 460 (2), 193-202
    DOI 10.1007/s00428-011-1191-x, PubMed 22249560
  3. Cejudo-Marín R, Tárrega C, Nunes-Xavier CE, Pulido R (2012)
    Caspase-3 cleavage of DUSP6/MKP3 at the interdomain region generates active MKP3 fragments that regulate ERK1/2 subcellular localization and function
    J Mol Biol, 420 (1-2), 128-38
    DOI 10.1016/j.jmb.2012.04.004, PubMed 22504224
  4. Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M (2012)
    Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism
    Nat Commun, 3, 1271
    DOI 10.1038/ncomms2236, PubMed 23232401
  5. Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad Ø (2012)
    Disseminated tumour cells in bone marrow of patients with uveal melanoma
    Acta Ophthalmol, 91 (4), 343-8
    DOI 10.1111/j.1755-3768.2012.02449.x, PubMed 22632270
  6. Ingebrigtsen VA, Boye K, Tekle C, Nesland JM, Flatmark K, Fodstad O (2012)
    B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer
    Int J Cancer, 131 (11), 2528-36
    DOI 10.1002/ijc.27566, PubMed 22473715
  7. Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M (2012)
    miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance
    J Biol Chem, 288 (6), 4334-45
    DOI 10.1074/jbc.M112.419168, PubMed 23255607
  8. Ree AH, Kristensen AT, Saelen MG, de Wijn R, Edvardsen H, Jovanovic J, Abrahamsen TW, Dueland S, Flatmark K (2012)
    Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer
    PLoS One, 7 (11), e50806
    DOI 10.1371/journal.pone.0050806, PubMed 23226389
  9. Saelen MG, Ree AH, Kristian A, Fleten KG, Furre T, Hektoen HH, Flatmark K (2012)
    Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma
    Radiat Oncol, 7, 165
    DOI 10.1186/1748-717X-7-165, PubMed 23017053
  10. Schee K, Boye K, Abrahamsen TW, Fodstad Ø, Flatmark K (2012)
    Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
    BMC Cancer, 12, 505
    DOI 10.1186/1471-2407-12-505, PubMed 23121918
  11. Schee K, Flatmark K, Holm R, Boye K, Paus E (2012)
    Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients (vol 33, pg 73, 2012)
    Tumor Biol., 33 (4), 1263-1264
  12. Sørensen O, Flatmark K, Reed W, Wiig JN, Dueland S, Giercksky KE, Larsen SG (2012)
    Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei
    Eur J Surg Oncol, 38 (10), 969-76
    DOI 10.1016/j.ejso.2012.06.552, PubMed 22763244
  13. Vincent AJ, Ren S, Harris LG, Devine DJ, Samant RS, Fodstad O, Shevde LA (2012)
    Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance
    FEBS Lett, 586 (19), 3429-34
    DOI 10.1016/j.febslet.2012.07.063, PubMed 22858377

Publications 2011

  1. Bratland A, Dueland S, Hollywood D, Flatmark K, Ree AH (2011)
    Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy
    Radiat Oncol, 6, 33
    DOI 10.1186/1748-717X-6-33, PubMed 21473790
  2. Bruheim S, Kristian A, Uenaka T, Suo Z, Tsuruoka A, Nesland JM, Fodstad Ø (2011)
    Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts
    Int J Cancer, 129 (3), 742-50
    DOI 10.1002/ijc.25922, PubMed 21225632
  3. Flatmark K, Borgen E, Nesland JM, Rasmussen H, Johannessen HO, Bukholm I, Rosales R, Hårklau L, Jacobsen HJ, Sandstad B, Boye K, Fodstad Ø (2011)
    Disseminated tumour cells as a prognostic biomarker in colorectal cancer
    Br J Cancer, 104 (9), 1434-9
    DOI 10.1038/bjc.2011.97, PubMed 21448171
  4. Hjortland GO, Meza-Zepeda LA, Beiske K, Ree AH, Tveito S, Hoifodt H, Bohler PJ, Hole KH, Myklebost O, Fodstad O, Smeland S, Hovig E (2011)
    Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
    BMC Cancer, 11, 455
    DOI 10.1186/1471-2407-11-455, PubMed 22014070
  5. Liu H, Tekle C, Chen YW, Kristian A, Zhao Y, Zhou M, Liu Z, Ding Y, Wang B, Mælandsmo GM, Nesland JM, Fodstad O, Tan M (2011)
    B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation
    Mol Cancer Ther, 10 (6), 960-71
    DOI 10.1158/1535-7163.MCT-11-0072, PubMed 21518725
  6. Nygren MK, Tekle C, Ingebrigtsen VA, Fodstad O (2011)
    B7-H3 and its relevance in cancer; immunological and non-immunological perspectives
    Front Biosci (Elite Ed), 3, 989-93
    DOI 10.2741/e304, PubMed 21622107
  7. Risberg K, Fodstad Ø, Andersson Y (2011)
    Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma
    PLoS One, 6 (9), e24012
    DOI 10.1371/journal.pone.0024012, PubMed 21915275
  8. Risberg K, Guldvik IJ, Palchaudhuri R, Xi Y, Ju J, Fodstad O, Hergenrother PJ, Andersson Y (2011)
    Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins
    J Immunother, 34 (5), 438-47
    DOI 10.1097/CJI.0b013e31821e00ae, PubMed 21577141
  9. Saelen MG, Flatmark K, Folkvord S, de Wijn R, Rasmussen H, Fodstad Ø, Ree AH (2011)
    Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination
    Angiogenesis, 14 (4), 481-9
    DOI 10.1007/s10456-011-9231-3, PubMed 21833622
  10. Schee K, Flatmark K, Holm R, Boye K, Paus E (2011)
    Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients
    Tumour Biol, 33 (1), 73-83
    DOI 10.1007/s13277-011-0247-5, PubMed 22006279
  11. Tekle C, Nygren MK, Chen YW, Dybsjord I, Nesland JM, Maelandsmo GM, Fodstad O (2011)
    B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
    Int J Cancer, 130 (10), 2282-90
    DOI 10.1002/ijc.26238, PubMed 21671471
  12. Tveito S, Andersen K, Kåresen R, Fodstad Ø (2011)
    Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles
    Breast Cancer Res, 13 (4), R75
    DOI 10.1186/bcr2922, PubMed 21816090
  13. Wang B, Howel P, Bruheim S, Ju J, Owen LB, Fodstad O, Xi Y (2011)
    Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array
    PLoS One, 6 (2), e17167
    DOI 10.1371/journal.pone.0017167, PubMed 21347261
  14. Wiig JN, Larsen SG, Dueland S, Flatmark K, Giercksky KE (2011)
    Salvage surgery for locally recurrent rectal cancer: total mesorectal excision during the primary operation does not influence the outcome
    Colorectal Dis, 13 (5), 506-11
    DOI 10.1111/j.1463-1318.2010.02256.x, PubMed 20236148
  15. Zhao Y, Liu H, Liu Z, Ding Y, Ledoux SP, Wilson GL, Voellmy R, Lin Y, Lin W, Nahta R, Liu B, Fodstad O, Chen J, Wu Y, Price JE, Tan M (2011)
    Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism
    Cancer Res, 71 (13), 4585-97
    DOI 10.1158/0008-5472.CAN-11-0127, PubMed 21498634
  16. Zhao Y, Liu H, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M (2011)
    Emerging metabolic targets in cancer therapy
    Front Biosci (Landmark Ed), 16, 1844-60
    DOI 10.2741/3826, PubMed 21196269

Publications 2010

  1. Berge G, Costea DE, Berg M, Rasmussen H, Grotterød I, Lothe RA, Mælandsmo GM, Flatmark K (2010)
    Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
    Amino Acids, 41 (4), 875-84
    DOI 10.1007/s00726-010-0514-6, PubMed 20191297
  2. Bergman AM, Adema AD, Balzarini J, Bruheim S, Fichtner I, Noordhuis P, Fodstad O, Myhren F, Sandvold ML, Hendriks HR, Peters GJ (2010)
    Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models
    Invest New Drugs, 29 (3), 456-66
    DOI 10.1007/s10637-009-9377-7, PubMed 20066470
  3. Boye K, Nesland JM, Sandstad B, Mælandsmo GM, Flatmark K (2010)
    Nuclear S100A4 is a novel prognostic marker in colorectal cancer
    Eur J Cancer, 46 (16), 2919-25
    DOI 10.1016/j.ejca.2010.07.013, PubMed 20719498
  4. Briggs JJ, Haugen MH, Johansen HT, Riker AI, Abrahamson M, Fodstad Ø, Maelandsmo GM, Solberg R (2010)
    Cystatin E/M suppresses legumain activity and invasion of human melanoma
    BMC Cancer, 10, 17
    DOI 10.1186/1471-2407-10-17, PubMed 20074384
  5. Flatmark K, Davidson B, Kristian A, Stavnes HT, Førsund M, Reed W (2010)
    Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models
    Hum Pathol, 41 (8), 1109-19
    DOI 10.1016/j.humpath.2009.12.013, PubMed 20338618
  6. Flatmark K, Ree AH (2010)
    Radiosensitizing drugs: lessons to be learned from the oxaliplatin story
    J Clin Oncol, 28 (29), e577-8; author reply e581-3
    DOI 10.1200/JCO.2010.30.0921, PubMed 20733124
  7. Folkvord S, Flatmark K, Dueland S, de Wijn R, Grøholt KK, Hole KH, Nesland JM, Ruijtenbeek R, Boender PJ, Johansen M, Giercksky KE, Ree AH (2010)
    Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling
    Int J Radiat Oncol Biol Phys, 78 (2), 555-62
    DOI 10.1016/j.ijrobp.2010.04.036, PubMed 20675069
  8. Mercapide J, Rappa G, Anzanello F, King J, Fodstad O, Lorico A (2010)
    Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma
    Int J Cancer, 126 (5), 1206-15
    DOI 10.1002/ijc.24809, PubMed 19653275
  9. Olberg DE, Cuthbertson A, Solbakken M, Arukwe JM, Qu H, Kristian A, Bruheim S, Hjelstuen OK (2010)
    Radiosynthesis and biodistribution of a prosthetic group (¹⁸F-FENMA) conjugated to cyclic RGD peptides
    Bioconjug Chem, 21 (12), 2297-304
    DOI 10.1021/bc1003229, PubMed 21070000
  10. Paus E, Haugen MH, Olsen KH, Flatmark K, Maelandsmo GM, Nilsson O, Röijer E, Lundin M, Fermér C, Samsonova M, Lebedin Y, Stigbrand T (2010)
    TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins
    Tumour Biol, 32 (1), 1-12
    DOI 10.1007/s13277-010-0073-1, PubMed 20652782
  11. Prasmickaite L, Skrbo N, Høifødt HK, Suo Z, Engebråten O, Gullestad HP, Aamdal S, Fodstad Ø, Maelandsmo GM (2010)
    Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
    Pigment Cell Melanoma Res, 23 (3), 449-51
    DOI 10.1111/j.1755-148X.2010.00690.x, PubMed 20236249
  12. Ree AH, Dueland S, Folkvord S, Hole KH, Seierstad T, Johansen M, Abrahamsen TW, Flatmark K (2010)
    Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study
    Lancet Oncol, 11 (5), 459-64
    DOI 10.1016/S1470-2045(10)70058-9, PubMed 20378407
  13. Risberg K, Fodstad O, Andersson Y (2010)
    Immunotoxins: a promising treatment modality for metastatic melanoma?
    Ochsner J, 10 (3), 193-9
    PubMed 21603377
  14. Risberg K, Fodstad O, Andersson Y (2010)
    Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells
    J Immunother, 33 (3), 272-8
    DOI 10.1097/CJI.0b013e3181c54991, PubMed 20445347
  15. Schee K, Fodstad Ø, Flatmark K (2010)
    MicroRNAs as biomarkers in colorectal cancer
    Am J Pathol, 177 (4), 1592-9
    DOI 10.2353/ajpath.2010.100024, PubMed 20829435
  16. Sørensen O, Andersen A, Olsen H, Alexandr K, Ekstrøm PO, Giercksky KE, Flatmark K (2010)
    Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study
    BMC Cancer, 10, 469
    DOI 10.1186/1471-2407-10-469, PubMed 20809961
  17. Tárrega C, Nunes-Xavier C, Cejudo-Marín R, Martín-Pérez J, Pulido R (2010)
    Studying the regulation of MAP Kinase by MAP Kinase phosphatases in vitro and in cell systems
    Methods Mol Biol, 661, 305-21
    DOI 10.1007/978-1-60761-795-2_18, PubMed 20811991
  18. Wiiger MT, Gehrken HB, Fodstad Ø, Maelandsmo GM, Andersson Y (2010)
    A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth
    Cancer Immunol Immunother, 59 (11), 1665-74
    DOI 10.1007/s00262-010-0892-3, PubMed 20635083
  19. Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M (2010)
    MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    J Biol Chem, 285 (28), 21496-507
    DOI 10.1074/jbc.M109.083337, PubMed 20460378
  20. Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M (2010)
    Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol
    Mol Cancer, 9, 33
    DOI 10.1186/1476-4598-9-33, PubMed 20144215

Publications 2009

  1. Andersson Y, Engebraaten O, Fodstad Ø (2009)
    Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo
    Br J Cancer, 101 (8), 1307-15
    DOI 10.1038/sj.bjc.6605312, PubMed 19773757
  2. Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
    Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
    Mol Oncol, 3 (5-6), 469-82
    DOI 10.1016/j.molonc.2009.07.003, PubMed 19713161
  3. Bratland A, Boender PJ, Høifødt HK, Østensen IH, Ruijtenbeek R, Wang MY, Berg JP, Lilleby W, Fodstad Ø, Ree AH (2009)
    Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling
    Clin Exp Metastasis, 26 (5), 485-96
    DOI 10.1007/s10585-009-9248-9, PubMed 19294521
  4. Bruheim S, Xi Y, Ju J, Fodstad O (2009)
    Gene expression profiles classify human osteosarcoma xenografts according to sensitivity to doxorubicin, cisplatin, and ifosfamide
    Clin Cancer Res, 15 (23), 7161-9
    DOI 10.1158/1078-0432.CCR-08-2816, PubMed 19920113
  5. Chowdhury UR, Samant RS, Fodstad O, Shevde LA (2009)
    Emerging role of nuclear protein 1 (NUPR1) in cancer biology
    Cancer Metastasis Rev, 28 (1-2), 225-32
    DOI 10.1007/s10555-009-9183-x, PubMed 19153668
  6. Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, Fodstad Ø (2009)
    Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
    Acta Ophthalmol, 87 (8), 830-6
    DOI 10.1111/j.1755-3768.2008.01378.x, PubMed 19055657
  7. Engebraaten O, Trikha M, Juell S, Garman-Vik S, Fodstad Ø (2009)
    Inhibition of in vivo tumour growth by the blocking of host alpha(v)beta3 and alphaII(b)beta3 integrins
    Anticancer Res, 29 (1), 131-7
    PubMed 19331142
  8. Folkvord S, Ree AH, Furre T, Halvorsen T, Flatmark K (2009)
    Radiosensitization by SAHA in experimental colorectal carcinoma models-in vivo effects and relevance of histone acetylation status
    Int J Radiat Oncol Biol Phys, 74 (2), 546-52
    DOI 10.1016/j.ijrobp.2009.01.068, PubMed 19427556
  9. Hoyem S, Bruheim S, Maelandsmo G, Standal M, Olberg DE, Brudeli B, Asberg A, Klaveness J, Rongved P (2009)
    Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats (vol 44, pg 3874, 2009)
    Eur. J. Med. Chem., 44 (11), 4786
  10. Høyem S, Bruheim S, Maelandsmo G, Olberg DE, Brudeli B, Asberg A, Klaveness J, Rongved P (2009)
    Didanosine ester prodrugs: synthesis, albumin binding properties and pharmacokinetic studies in rats
    Eur J Med Chem, 44 (10), 3874-9
    DOI 10.1016/j.ejmech.2009.04.008, PubMed 19433342
  11. Liu S, Howell P, Ren S, Fodstad O, Riker AI (2009)
    The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma
    BMC Cancer, 9, 162
    DOI 10.1186/1471-2407-9-162, PubMed 19473536
  12. Liu S, Howell P, Ren S, Fodstad O, Zhang G, Samant R, Shevde L, Xi Y, Pannell LK, Riker AI (2009)
    Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma
    Clin Exp Metastasis, 26 (7), 739-49
    DOI 10.1007/s10585-009-9273-8, PubMed 19488830
  13. Maelandsmo GM, Flørenes VA, Nguyen MT, Flatmark K, Davidson B (2009)
    Different expression and clinical role of S100A4 in serous ovarian carcinoma at different anatomic sites
    Tumour Biol, 30 (1), 15-25
    DOI 10.1159/000199447, PubMed 19194111
  14. Ren S, Liu S, Howell PM, Zhang G, Pannell L, Samant R, Shevde-Samant L, Tucker JA, Fodstad O, Riker AI (2009)
    Functional characterization of the progestagen-associated endometrial protein gene in human melanoma
    J Cell Mol Med, 14 (6B), 1432-42
    DOI 10.1111/j.1582-4934.2009.00922.x, PubMed 19799645
  15. Risberg K, Fodstad Ø, Andersson Y (2009)
    The melanoma specific 9.2.27PE immunotoxin efficiently kills melanoma cells in vitro
    Int J Cancer, 125 (1), 23-33
    DOI 10.1002/ijc.24317, PubMed 19350633
  16. Seierstad T, Hole KH, Saelen E, Ree AH, Flatmark K, Malinen E (2009)
    MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy
    Radiother Oncol, 93 (2), 279-84
    DOI 10.1016/j.radonc.2009.08.046, PubMed 19800704
  17. Song B, Wang Y, Xi Y, Kudo K, Bruheim S, Botchkina GI, Gavin E, Wan Y, Formentini A, Kornmann M, Fodstad O, Ju J (2009)
    Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
    Oncogene, 28 (46), 4065-74
    DOI 10.1038/onc.2009.274, PubMed 19734943
  18. Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M (2009)
    Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
    Oncogene, 28 (42), 3689-701
    DOI 10.1038/onc.2009.229, PubMed 19668225

Publications 2008

  1. Brunsvig PF, Flatmark K, Aamdal S, Høifødt H, Le H, Jakobsen E, Sandstad B, Fodstad O (2008)
    Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
    Lung Cancer, 61 (2), 170-6
    DOI 10.1016/j.lungcan.2007.12.018, PubMed 18261824
  2. Faye RS, Paus E, Maelandsmo GM, Berner A, Høifødt HK, Fodstad Ø, Aamdal S (2008)
    S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
    Melanoma Res, 18 (2), 134-40
    DOI 10.1097/CMR.0b013e3282f623d9, PubMed 18337650
  3. Haugen MH, Flatmark K, Mikalsen SO, Malandsmo GM (2008)
    The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
    BMC Cancer, 8, 172
    DOI 10.1186/1471-2407-8-172, PubMed 18554396
  4. Kristensen AT, Wiig JN, Larsen SG, Giercksky KE, Ekstrøm PO (2008)
    Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer?
    BMC Cancer, 8, 213
    DOI 10.1186/1471-2407-8-213, PubMed 18655729
  5. Ree AH, Folkvord S, Flatmark K (2008)
    HDAC2 deficiency and histone acetylation
    Nat Genet, 40 (7), 812-3; author reply 813
    DOI 10.1038/ng0708-812, PubMed 18583969
  6. Seierstad T, Røe K, Sitter B, Halgunset J, Flatmark K, Ree AH, Olsen DR, Gribbestad IS, Bathen TF (2008)
    Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy
    Mol Cancer, 7, 33
    DOI 10.1186/1476-4598-7-33, PubMed 18439252

Publications 2007

  1. Bauer NN, Chen YW, Samant RS, Shevde LA, Fodstad O (2007)
    Rac1 activity regulates proliferation of aggressive metastatic melanoma
    Exp Cell Res, 313 (18), 3832-9
    DOI 10.1016/j.yexcr.2007.08.017, PubMed 17904119
  2. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
    Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
    BMC Genomics, 8, 273
    DOI 10.1186/1471-2164-8-273, PubMed 17692132
  3. Flatmark K, Reed W, Halvorsen T, Sørensen O, Wiig JN, Larsen SG, Fodstad Ø, Giercksky KE (2007)
    Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype
    BMC Cancer, 7, 116
    DOI 10.1186/1471-2407-7-116, PubMed 17603904
  4. Fodstad Ø (2007)
    [The 75th anniversary of the Radium Hospital]
    Tidsskr Nor Laegeforen, 127 (13), 1800-1
    PubMed 17599133
  5. Folkvord S, Flatmark K, Seierstad T, Røe K, Rasmussen H, Ree AH (2007)
    Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity?
    Radiother Oncol, 86 (3), 428-34
    DOI 10.1016/j.radonc.2007.10.012, PubMed 18006097
  6. Lillehammer T, Engesaeter BO, Prasmickaite L, Maelandsmo GM, Fodstad O, Engebraaten O (2007)
    Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines
    J Gene Med, 9 (6), 440-51
    DOI 10.1002/jgm.1036, PubMed 17410615
  7. Seierstad T, Folkvord S, Røe K, Flatmark K, Skretting A, Olsen DR (2007)
    Early changes in apparent diffusion coefficient predict the quantitative antitumoral activity of capecitabine, oxaliplatin, and irradiation in HT29 xenografts in athymic nude mice
    Neoplasia, 9 (5), 392-400
    DOI 10.1593/neo.07154, PubMed 17534444
  8. Thies A, Mauer S, Fodstad O, Schumacher U (2007)
    Clinically proven markers of metastasis predict metastatic spread of human melanoma cells engrafted in scid mice
    Br J Cancer, 96 (4), 609-16
    DOI 10.1038/sj.bjc.6603594, PubMed 17262079
  9. Tveito S, Maelandsmo GM, Hoifodt HK, Rasmussen H, Fodstad O (2007)
    Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value
    Clin Exp Metastasis, 24 (5), 317-27
    DOI 10.1007/s10585-006-9052-8, PubMed 17530423

Publications 2006

  1. Andersson Y, Le H, Juell S, Fodstad Ø (2006)
    AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death
    Mol Cancer Ther, 5 (4), 1050-9
    DOI 10.1158/1535-7163.MCT-05-0318, PubMed 16648577
  2. Boye K, Andersen K, Tveito S, Øyjord T, Maelandsmo GM (2006)
    Interferon-gamma-induced suppression of S100A4 transcription is mediated by the class II transactivator
    Tumour Biol, 28 (1), 27-35
    DOI 10.1159/000097700, PubMed 17143014
  3. Engesaeter BØ, Tveito S, Bonsted A, Engebraaten O, Berg K, Maelandsmo GM (2006)
    Photochemical treatment with endosomally localized photosensitizers enhances the number of adenoviruses in the nucleus
    J Gene Med, 8 (6), 707-18
    DOI 10.1002/jgm.902, PubMed 16518880
  4. Flatmark K, Nome RV, Folkvord S, Bratland A, Rasmussen H, Ellefsen MS, Fodstad Ø, Ree AH (2006)
    Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
    Radiat Oncol, 1, 25
    DOI 10.1186/1748-717X-1-25, PubMed 16887021
  5. Jiang WG, Davies G, Kynaston H, Mason MD, Fodstad O (2006)
    Does the PGC-1/PPARgamma pathway play a role in Com-1/p8 mediated cell growth inhibition in prostate cancer?
    Int J Mol Med, 18 (6), 1169-75
    PubMed 17089023
  6. Jiang WG, Davies G, Martin TA, Kynaston H, Mason MD, Fodstad O (2006)
    Com-1/p8 acts as a putative tumour suppressor in prostate cancer
    Int J Mol Med, 18 (5), 981-6
    PubMed 17016631
  7. Mbeunkui F, Fodstad O, Pannell LK (2006)
    Secretory protein enrichment and analysis: an optimized approach applied on cancer cell lines using 2D LC-MS/MS
    J Proteome Res, 5 (4), 899-906
    DOI 10.1021/pr050375p, PubMed 16602697
  8. Ree AH, Stokke T, Bratland A, Patzke S, Nome RV, Folkvord S, Meza-Zepeda LA, Flatmark K, Fodstad O, Andersson Y (2006)
    DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
    Anticancer Res, 26 (3A), 1909-16
    PubMed 16827124

Publications 2005

  1. Bjørnland K, Flatmark K, Pettersen S, Aaasen AO, Fodstad O, Maelandsmo GM (2005)
    Matrix metalloproteinases participate in osteosarcoma invasion
    J Surg Res, 127 (2), 151-6
    DOI 10.1016/j.jss.2004.12.016, PubMed 16083752
  2. Bruland OS, Høifødt H, Saeter G, Smeland S, Fodstad O (2005)
    Hematogenous micrometastases in osteosarcoma patients
    Clin Cancer Res, 11 (13), 4666-73
    DOI 10.1158/1078-0432.CCR-05-0165, PubMed 16000559
  3. Engesaeter BØ, Bonsted A, Berg K, Høgset A, Engebråten O, Fodstad Ø, Curiel DT, Maelandsmo GM (2005)
    PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles
    Cancer Gene Ther, 12 (5), 439-48
    DOI 10.1038/sj.cgt.7700808, PubMed 15678152
  4. Hinselwood DC, Abrahamsen TW, Ekstrøm PO (2005)
    BRAF mutation detection and identification by cycling temperature capillary electrophoresis
    Electrophoresis, 26 (13), 2553-61
    DOI 10.1002/elps.200410427, PubMed 15948220
  5. Holthe MR, Andersson Y, Lyberg T (2005)
    Lack of proinflammatory effects of free fatty acids on human umbilical cord vein endothelial cells and leukocytes
    Acta Obstet Gynecol Scand, 84 (7), 672-8
    DOI 10.1111/j.0001-6349.2005.00799.x, PubMed 15954878
  6. Jiang WG, Davies G, Fodstad O (2005)
    Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection
    Biochem Biophys Res Commun, 330 (1), 253-62
    DOI 10.1016/j.bbrc.2005.02.157, PubMed 15781258
  7. Jiang WG, Watkins G, Douglas-Jones A, Mokbel K, Mansel RE, Fodstad O (2005)
    Expression of Com-1/P8 in human breast cancer and its relevance to clinical outcome and ER status
    Int J Cancer, 117 (5), 730-7
    DOI 10.1002/ijc.21221, PubMed 15957166
  8. Lillehammer T, Tveito S, Engesaeter BO, Fodstad O, Maelandsmo GM, Engebraaten O (2005)
    Melanoma-specific expression in first-generation adenoviral vectors in vitro and in vivo -- use of the human tyrosinase promoter with human enhancers
    Cancer Gene Ther, 12 (11), 864-72
    DOI 10.1038/sj.cgt.7700852, PubMed 15891771
  9. Lorico A, Bratbak D, Meyer J, Kunke D, Krauss S, Plott WE, Solodushko V, Baum C, Fodstad O, Rappa G (2005)
    Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells
    Hum Gene Ther, 16 (6), 711-24
    DOI 10.1089/hum.2005.16.711, PubMed 15960602
  10. Lund T, Stokke T, Olsen ØE, Fodstad Ø (2005)
    Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein BimEL and induces apoptosis
    Br J Cancer, 92 (9), 1773-81
    DOI 10.1038/sj.bjc.6602537, PubMed 15827557
  11. Matsumoto T, Bohman S, Dixelius J, Berge T, Dimberg A, Magnusson P, Wang L, Wikner C, Qi JH, Wernstedt C, Wu J, Bruheim S, Mugishima H, Mukhopadhyay D, Spurkland A, Claesson-Welsh L (2005)
    VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis
    EMBO J, 24 (13), 2342-53
    DOI 10.1038/sj.emboj.7600709, PubMed 15962004
  12. Nome RV, Bratland A, Harman G, Fodstad O, Andersson Y, Ree AH (2005)
    Cell cycle checkpoint signaling involved in histone deacetylase inhibition and radiation-induced cell death
    Mol Cancer Ther, 4 (8), 1231-8
    DOI 10.1158/1535-7163.MCT-04-0304, PubMed 16093439

Publications 2004

  1. Andersen K, Nesland JM, Holm R, Flørenes VA, Fodstad Ø, Maelandsmo GM (2004)
    Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma
    Mod Pathol, 17 (8), 990-7
    DOI 10.1038/modpathol.3800151, PubMed 15133476
  2. Andersson Y, Juell S, Fodstad Ø (2004)
    Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin
    Int J Cancer, 112 (3), 475-83
    DOI 10.1002/ijc.20371, PubMed 15382075
  3. Bergman AM, Kuiper CM, Noordhuis P, Smid K, Voorn DA, Comijn EM, Myhren F, Sandvold ML, Hendriks HR, Fodstad O, Breistøl K, Peters GJ (2004)
    Antiproliferative activity and mechanism of action of fatty acid derivatives of gemcitabine in leukemia and solid tumor cell lines and in human xenografts
    Nucleosides Nucleotides Nucleic Acids, 23 (8-9), 1329-33
    DOI 10.1081/NCN-200027579, PubMed 15571253
  4. Bruheim S, Bruland OS, Breistol K, Maelandsmo GM, Fodstad O (2004)
    Human osteosarcoma xenografts and their sensitivity to chemotherapy
    Pathol Oncol Res, 10 (3), 133-41
    DOI 10.1007/bf03033741, PubMed 15448748
  5. Choesmel V, Anract P, Høifødt H, Thiery JP, Blin N (2004)
    A relevant immunomagnetic assay to detect and characterize epithelial cell adhesion molecule-positive cells in bone marrow from patients with breast carcinoma: immunomagnetic purification of micrometastases
    Cancer, 101 (4), 693-703
    DOI 10.1002/cncr.20391, PubMed 15305398
  6. Fagerlund A, Ween O, Lund T, Hardy SP, Granum PE (2004)
    Genetic and functional analysis of the cytK family of genes in Bacillus cereus
    Microbiology, 150 (Pt 8), 2689-97
    DOI 10.1099/mic.0.26975-0, PubMed 15289565
  7. Faye RS, Aamdal S, Høifødt HK, Jacobsen E, Holstad L, Skovlund E, Fodstad Ø (2004)
    Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
    Clin Cancer Res, 10 (12 Pt 1), 4134-9
    DOI 10.1158/1078-0432.CCR-03-0408, PubMed 15217950
  8. Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H, Fodstad Ø (2004)
    Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
    Eur J Cancer, 40 (10), 1593-8
    DOI 10.1016/j.ejca.2004.02.023, PubMed 15196545
  9. Flatmark K, Maelandsmo GM, Mikalsen SO, Nustad K, Varaas T, Rasmussen H, Meling GI, Fodstad Ø, Paus E (2004)
    Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum
    Tumour Biol, 25 (1-2), 31-40
    DOI 10.1159/000077721, PubMed 15192310
  10. Hjortland GO, Garman-Vik SS, Juell S, Olsen OE, Hirschberg H, Fodstad O, Engebraaten O (2004)
    Immunotoxin treatment targeted to the high-molecular-weight melanoma-associated antigen prolonging the survival of immunodeficient rats with invasive intracranial human glioblastoma multiforme
    J Neurosurg, 100 (2), 320-7
    DOI 10.3171/jns.2004.100.2.0320, PubMed 15086240
  11. Hjortland GO, Lillehammer T, Somme S, Wang J, Halvorsen T, Juell S, Hirschberg H, Fodstad Ø, Engebraaten O (2004)
    Plasminogen activator inhibitor-1 increases the expression of VEGF in human glioma cells
    Exp Cell Res, 294 (1), 130-9
    DOI 10.1016/j.yexcr.2003.10.013, PubMed 14980508
  12. Jiang WG, Watkins G, Fodstad O, Douglas-Jones A, Mokbel K, Mansel RE (2004)
    Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer
    Endocr Relat Cancer, 11 (4), 781-91
    DOI 10.1677/erc.1.00825, PubMed 15613452
  13. King JA, Ofori-Acquah SF, Stevens T, Al-Mehdi AB, Fodstad O, Jiang WG (2004)
    Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator
    Breast Cancer Res, 6 (5), R478-87
    DOI 10.1186/bcr815, PubMed 15318930
  14. Pedersen KB, Andersen K, Fodstad Ø, Maelandsmo GM (2004)
    Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4
    BMC Cancer, 4, 52
    DOI 10.1186/1471-2407-4-52, PubMed 15318945
  15. Rappa G, Kunke D, Holter J, Diep DB, Meyer J, Baum C, Fodstad O, Krauss S, Lorico A (2004)
    Efficient expansion and gene transduction of mouse neural stem/progenitor cells on recombinant fibronectin
    Neuroscience, 124 (4), 823-30
    DOI 10.1016/j.neuroscience.2003.11.030, PubMed 15026123
  16. Ree AH, Bratland A, Nome RV, Stokke T, Fodstad O, Andersson Y (2004)
    Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?
    Radiother Oncol, 72 (3), 305-10
    DOI 10.1016/j.radonc.2004.07.002, PubMed 15450729
  17. Ree AH, Bratland A, Solberg Landsverk K, Fodstad O (2004)
    Ionizing radiation inhibits the PLK cell cycle gene in a G2 checkpoint-dependent manner
    Anticancer Res, 24 (2B), 555-62
    PubMed 15160994
  18. Wang X, Wang M, Amarzguioui M, Liu F, Fodstad Ø, Prydz H (2004)
    Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Int J Cancer, 112 (6), 994-1002
    DOI 10.1002/ijc.20527, PubMed 15386437

Publications 2003

  1. Andersen K, Smith-Sørensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad Ø, Maelandsmo GM (2003)
    Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
    Br J Cancer, 88 (12), 1995-2001
    DOI 10.1038/sj.bjc.6600998, PubMed 12799648
  2. Bjørheim J, Abrahamsen TW, Kristensen AT, Gaudernack G, Ekstrøm PO (2003)
    Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis
    Mutat Res, 526 (1-2), 75-83
    DOI 10.1016/s0027-5107(03)00033-2, PubMed 12714185
  3. Bjørnland K, Flatmark K, Mala T, Mathisen O, Bakka A, Aasen AO, Bergan A, Søreide O, Fodstad O (2003)
    Detection of disseminated tumour cells in bone marrow of patients with isolated liver metastases from colorectal cancer
    J Surg Oncol, 82 (4), 224-7
    DOI 10.1002/jso.10223, PubMed 12672004
  4. Bratland A, Ragnhildstveit E, Bjørnland K, Andersen K, Maelandsmo GM, Fodstad O, Saatcioglu F, Ree AH (2003)
    The metalloproteinase inhibitor TIMP-2 is down-regulated by androgens in LNCaP prostate carcinoma cells
    Clin Exp Metastasis, 20 (6), 541-7
    DOI 10.1023/a:1025860214891, PubMed 14598888
  5. Dale O, Bergum H, Lund T, Nilsen T, Aadahl P, Stenseth R (2003)
    A validated method for rapid analysis of ethane in breath and its application in kinetic studies in human volunteers
    Free Radic Res, 37 (8), 815-21
    DOI 10.1080/1071576031000107353, PubMed 14567440
  6. Flatmark K, Pedersen KB, Nesland JM, Rasmussen H, Aamodt G, Mikalsen SO, Bjørnland K, Fodstad Ø, Maelandsmo GM (2003)
    Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer
    J Pathol, 200 (5), 589-95
    DOI 10.1002/path.1381, PubMed 12898594
  7. Guren TK, Ødegård J, Abrahamsen H, Thoresen GH, Susa M, Andersson Y, Østby E, Christoffersen T (2003)
    EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes
    J Cell Physiol, 196 (1), 113-23
    DOI 10.1002/jcp.10282, PubMed 12767047
  8. Hjortland GO, Bjørnland K, Pettersen S, Garman-Vik SS, Emilsen E, Nesland JM, Fodstad O, Engebraaten O (2003)
    Modulation of glioma cell invasion and motility by adenoviral gene transfer of PAI-1
    Clin Exp Metastasis, 20 (4), 301-9
    DOI 10.1023/a:1024040718238, PubMed 12856717
  9. Kristensen AT, Bjørheim J, Wiig J, Giercksky KE, Ekstrøm PO (2003)
    DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study
    Int J Colorectal Dis, 19 (1), 49-54
    DOI 10.1007/s00384-003-0519-7, PubMed 12827413
  10. Maelandsmo GM, Holm R, Nesland JM, Fodstad Ø, Flørenes VA (2003)
    Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma
    Clin Cancer Res, 9 (9), 3383-8
    PubMed 12960126
  11. Mathisen B, Lindstad RI, Hansen J, El-Gewely SA, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (2003)
    S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells
    Clin Exp Metastasis, 20 (8), 701-11
    DOI 10.1023/b:clin.0000006819.21361.03, PubMed 14713104
  12. Nygaard V, Løland A, Holden M, Langaas M, Rue H, Liu F, Myklebost O, Fodstad Ø, Hovig E, Smith-Sørensen B (2003)
    Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    BMC Genomics, 4 (1), 11
    DOI 10.1186/1471-2164-4-11, PubMed 12659661
  13. Rappa G, Gamcsik MP, Mitina RL, Baum C, Fodstad O, Lorico A (2003)
    Retroviral transfer of MRP1 and gamma-glutamyl cysteine synthetase modulates cell sensitivity to L-buthionine-S,R-sulphoximine (BSO): new rationale for the use of BSO in cancer therapy
    Eur J Cancer, 39 (1), 120-8
    DOI 10.1016/s0959-8049(02)00447-1, PubMed 12504668
  14. Ree AH, Bratland A, Nome RV, Stokke T, Fodstad Ø (2003)
    Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1
    Oncogene, 22 (55), 8952-5
    DOI 10.1038/sj.onc.1207000, PubMed 14654792

Publications 2002

  1. Engebraaten O, Hjortland GO, Juell S, Hirschberg H, Fodstad O (2002)
    Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals
    Int J Cancer, 97 (6), 846-52
    DOI 10.1002/ijc.10137, PubMed 11857366
  2. Flatmark K, Bjørnland K, Johannessen HO, Hegstad E, Rosales R, Hårklau L, Solhaug JH, Faye RS, Søreide O, Fodstad Ø, Study Group for Micrometastases in BM in Colorectal Cancer (2002)
    Immunomagnetic detection of micrometastatic cells in bone marrow of colorectal cancer patients
    Clin Cancer Res, 8 (2), 444-9
    PubMed 11839662
  3. Henriksen G, Breistøl K, Bruland ØS, Fodstad Ø, Larsen RH (2002)
    Significant antitumor effect from bone-seeking, alpha-particle-emitting (223)Ra demonstrated in an experimental skeletal metastases model
    Cancer Res, 62 (11), 3120-5
    PubMed 12036923
  4. Høgset A, Engesaeter BO, Prasmickaite L, Berg K, Fodstad O, Maelandsmo GM (2002)
    Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy
    Cancer Gene Ther, 9 (4), 365-71
    DOI 10.1038/sj.cgt.7700447, PubMed 11960287
  5. Lorico A, Bertola A, Baum C, Fodstad O, Rappa G (2002)
    Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice
    Biochem Biophys Res Commun, 291 (3), 617-22
    DOI 10.1006/bbrc.2002.6489, PubMed 11855834
  6. Lorico A, Nesland J, Emilsen E, Fodstad O, Rappa G (2002)
    Role of the multidrug resistance protein 1 gene in the carcinogenicity of aflatoxin B1: investigations using mrp1-null mice
    Toxicology, 171 (2-3), 201-5
    DOI 10.1016/s0300-483x(01)00584-4, PubMed 11836025
  7. Marth C, Kisic J, Kaern J, Tropé C, Fodstad Ø (2002)
    Circulating tumor cells in the peripheral blood and bone marrow of patients with ovarian carcinoma do not predict prognosis
    Cancer, 94 (3), 707-12
    DOI 10.1002/cncr.10250, PubMed 11857303
  8. Pedersen KB, Nesland JM, Fodstad Ø, Maelandsmo GM (2002)
    Expression of S100A4, E-cadherin, alpha- and beta-catenin in breast cancer biopsies
    Br J Cancer, 87 (11), 1281-6
    DOI 10.1038/sj.bjc.6600624, PubMed 12439718
  9. Ree AH, Bratland A, Kroes RA, Aasheim HC, Flørenes VA, Moskal JR, Fodstad O, Bruland OS, Maelandsmo GM (2002)
    Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases
    Anticancer Res, 22 (4), 1949-57
    PubMed 12174869
  10. Ree AH, Engebraaten O, Hovig E, Fodstad Ø (2002)
    Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells
    Int J Cancer, 97 (1), 28-33
    DOI 10.1002/ijc.1564, PubMed 11774240
  11. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
    Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    Oncogene, 21 (57), 8878-84
    DOI 10.1038/sj.onc.1205978, PubMed 12483540

Publications 2001

  1. Bjørnland K, Bratland A, Rugnes E, Pettersen S, Johansen HT, Aasen AO, Fodstad Ø, Ree AH, Maelandsmo GM (2001)
    Expression of matrix metalloproteinases and the metastasis-associated gene S100A4 in human neuroblastoma and primitive neuroectodermal tumor cells
    J Pediatr Surg, 36 (7), 1040-4
    DOI 10.1053/jpsu.2001.24735, PubMed 11431772
  2. Fodstad O, Faye R, Høifødt HK, Skovlund E, Aamdal S (2001)
    Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
    Recent Results Cancer Res, 158, 40-50
    DOI 10.1007/978-3-642-59537-0_5, PubMed 11092032
  3. Forus A, D'Angelo A, Henriksen J, Merla G, Maelandsmo GM, Flørenes VA, Olivieri S, Bjerkehagen B, Meza-Zepeda LA, del Vecchio Blanco F, Müller C, Sanvito F, Kononen J, Nesland JM, Fodstad Ø, Reymond A, Kallioniemi OP, Arrigoni G, Ballabio A, Myklebost O, Zollo M (2001)
    Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity
    Oncogene, 20 (47), 6881-90
    DOI 10.1038/sj.onc.1204874, PubMed 11687967
  4. Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J (2001)
    Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
    Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
    DOI 10.1089/108729001750171272, PubMed 11334142
  5. Ivanov VN, Fodstad O, Ronai Z (2001)
    Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities
    Oncogene, 20 (18), 2243-53
    DOI 10.1038/sj.onc.1204314, PubMed 11402319
  6. Rappa G, Lorico A, Hildinger M, Fodstad Ø, Baum C (2001)
    Novel bicistronic retroviral vector expressing gamma-glutamylcysteine synthetase and the multidrug resistance protein 1 (MRP1) protects cells from MRP1-effluxed drugs and alkylating agents
    Hum Gene Ther, 12 (14), 1785-96
    DOI 10.1089/104303401750476276, PubMed 11560771
  7. Siewert C, Herber M, Hunzelmann N, Fodstad O, Miltenyi S, Assenmacher M, Schmitz J (2001)
    Rapid enrichment and detection of melanoma cells from peripheral blood mononuclear cells by a new assay combining immunomagnetic cell sorting and immunocytochemical staining
    Recent Results Cancer Res, 158, 51-60
    DOI 10.1007/978-3-642-59537-0_6, PubMed 11092033

Publications 2000

  1. Bratland A, Risberg K, Maelandsmo GM, Gützkow KB, Olsen OE, Moghaddam A, Wang MY, Hansen CM, Blomhoff HK, Berg JP, Fodstad O, Ree AH (2000)
    Expression of a novel factor, com1, is regulated by 1,25-dihydroxyvitamin D3 in breast cancer cells
    Cancer Res, 60 (19), 5578-83
    PubMed 11034106
  2. Engebraaten O, Sivam G, Juell S, Fodstad O (2000)
    Systemic immunotoxin treatment inhibits formation of human breast cancer metastasis and tumor growth in nude rats
    Int J Cancer, 88 (6), 970-6
    DOI 10.1002/1097-0215(20001215)88:6<970::aid-ijc21>3.0.co;2-q, PubMed 11093823
  3. Rappa G, Shyam K, Lorico A, Fodstad O, Sartorelli AC (2000)
    Structure-activity studies of novobiocin analogs as modulators of the cytotoxicity of etoposide (VP-16)
    Oncol Res, 12 (3), 113-9
    DOI 10.3727/096504001108747585, PubMed 11216669
  4. Ree AH, Pacheco MM, Tvermyr M, Fodstad O, Brentani MM (2000)
    Expression of a novel factor, com1, in early tumor progression of breast cancer
    Clin Cancer Res, 6 (5), 1778-83
    PubMed 10815897
  5. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
    Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
    Int J Cancer, 87 (6), 853-9
    DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397

Publications 1999

  1. Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
    Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
    Cancer Res, 59 (6), 1180-3
    PubMed 10096543
  2. Bjørnland K, Winberg JO, Odegaard OT, Hovig E, Loennechen T, Aasen AO, Fodstad O, Maelandsmo GM (1999)
    S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
    Cancer Res, 59 (18), 4702-8
    PubMed 10493528
  3. Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad O, Diel I, Solomayer EF, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau JP, Garcia J, Pantel K (1999)
    Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
    Cytotherapy, 1 (5), 377-88
    DOI 10.1080/0032472031000141283, PubMed 20426539
  4. Breistøl K, Balzarini J, Sandvold ML, Myhren F, Martinsen M, De Clercq E, Fodstad O (1999)
    Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in metastatic and s.c. human tumor xenograft models
    Cancer Res, 59 (12), 2944-9
    PubMed 10383159
  5. Breistøl K, Hendriks HR, Fodstad O (1999)
    Superior therapeutic efficacy of N-L-leucyl-doxorubicin versus doxorubicin in human melanoma xenografts correlates with higher tumour concentrations of free drug
    Eur J Cancer, 35 (7), 1143-9
    DOI 10.1016/s0959-8049(99)00074-x, PubMed 10533461
  6. Engebraaten O, Fodstad O (1999)
    Site-specific experimental metastasis patterns of two human breast cancer cell lines in nude rats
    Int J Cancer, 82 (2), 219-25
    DOI 10.1002/(sici)1097-0215(19990719)82:2<219::aid-ijc12>3.0.co;2-#, PubMed 10389756
  7. Engebraaten O, Hjortland GO, Hirschberg H, Fodstad O (1999)
    Growth of precultured human glioma specimens in nude rat brain
    J Neurosurg, 90 (1), 125-32
    DOI 10.3171/jns.1999.90.1.0125, PubMed 10413165
  8. Forus A, Høifødt HK, Overli GE, Myklebost O, Fodstad O (1999)
    Sensitive fluorescent in situ hybridisation method for the characterisation of breast cancer cells in bone marrow aspirates
    Mol Pathol, 52 (2), 68-74
    DOI 10.1136/mp.52.2.68, PubMed 10474684
  9. Pantel K, Cote RJ, Fodstad O (1999)
    Detection and clinical importance of micrometastatic disease
    J Natl Cancer Inst, 91 (13), 1113-24
    DOI 10.1093/jnci/91.13.1113, PubMed 10393719
  10. Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
    Expression of a novel factor in human breast cancer cells with metastatic potential
    Cancer Res, 59 (18), 4675-80
    PubMed 10493524
  11. Ruud P, Fodstad O, Hovig E (1999)
    Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
    Int J Cancer, 80 (1), 119-25
    DOI 10.1002/(sici)1097-0215(19990105)80:1<119::aid-ijc22>3.0.co;2-x, PubMed 9935241
 
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