Publications

Publications by Jan E. Brinchmann

93 publications found

Publications 2019

  1. Al-Modawi RN, Brinchmann JE, Karlsen TA (2019)
    Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis
    Mol Ther Nucleic Acids, 17, 776-790
    DOI 10.1016/j.omtn.2019.07.011, PubMed 31446120
  2. Karlsen TA, Sundaram AYM, Brinchmann JE (2019)
    Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets
    Cartilage, 1947603519847746 (in press)
    DOI 10.1177/1947603519847746, PubMed 31072202
  3. Kosik-Koziol A, Costantini M, Mroz A, Idaszek J, Heljak M, Jaroszewicz J, Kijenska E, Szoke K, Frerker N, Barbetta A, Brinchmann JE, Swieszkowski W (2019)
    3D bioprinted hydrogel model incorporating beta-tricalcium phosphate for calcified cartilage tissue engineering
    Biofabrication, 11 (3), UNSP 035016
  4. Kosik-Kozioł A, Costantini M, Mróz A, Idaszek J, Heljak M, Jaroszewicz J, Kijeńska E, Szöke K, Frerker N, Barbetta A, Brinchmann JE, Święszkowski W (2019)
    3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering
    Biofabrication, 11 (3), 035016
    DOI 10.1088/1758-5090/ab15cb, PubMed 30943457

Publications 2018

  1. Brinchmann BC, Skuland T, Rambøl MH, Szoke K, Brinchmann JE, Gutleb AC, Moschini E, Kubátová A, Kukowski K, Le Ferrec E, Lagadic-Gossmann D, Schwarze PE, Låg M, Refsnes M, Øvrevik J, Holme JA (2018)
    Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)
    Part Fibre Toxicol, 15 (1), 21
    DOI 10.1186/s12989-018-0257-1, PubMed 29751765
  2. Karlsen TA, Brinchmann JE (2018)
    Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulations
    Exp Cell Res, 374 (1), 122-127
    DOI 10.1016/j.yexcr.2018.11.014, PubMed 30496759
  3. Rambøl MH, Hisdal J, Sundhagen JO, Brinchmann JE, Rosales A (2018)
    Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation
    EBioMedicine, 32, 215-222
    DOI 10.1016/j.ebiom.2018.05.012, PubMed 29779699

Publications 2017

  1. Kosik-Kozioł A, Costantini M, Bolek T, Szoke K, Barbetta A, Brinchmann JE, Święszkowski W (2017)
    PLA short sub-micron fibers reinforcement of 3D bioprinted alginate constructs for cartilage regeneration
    Biofabrication, 9 (4), 044105
    DOI 10.1088/1758-5090/aa90d7, PubMed 28975895
  2. Szoke K, Dankova J, Buzgo M, Amler E, Brinchmann JE, Ostrup E (2017)
    The effect of medium composition on deposition of collagen type 1 and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow
    Process Biochem., 59, 321-328
  3. Wollert KC, Meyer GP, Müller-Ehmsen J, Tschöpe C, Bonarjee V, Larsen AI, May AE, Empen K, Chorianopoulos E, Tebbe U, Waltenberger J, Mahrholdt H, Ritter B, Pirr J, Fischer D, Korf-Klingebiel M, Arseniev L, Heuft HG, Brinchmann JE, Messinger D, Hertenstein B, Ganser A, Katus HA, Felix SB, Gawaz MP et al. (2017)
    Intracoronary autologous bone marrow cell transfer after myocardial infarction: the BOOST-2 randomised placebo-controlled clinical trial
    Eur Heart J, 38 (39), 2936-2943
    DOI 10.1093/eurheartj/ehx188, PubMed 28431003

Publications 2016

  1. Behnan J, Stangeland B, Hosainey SA, Joel M, Olsen TK, Micci F, Glover JC, Isakson P, Brinchmann JE (2016)
    Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
    Oncogene, 36 (4), 570-584
    DOI 10.1038/onc.2016.230, PubMed 27345406
  2. Behnan J, Stangeland B, Langella T, Finocchiaro G, Murrell W, Brinchmann JE (2016)
    Ultrasonic Surgical Aspirate is a Reliable Source For Culturing Glioblastoma Stem Cells
    Sci Rep, 6, 32788
    DOI 10.1038/srep32788, PubMed 27605047
  3. Costantini M, Idaszek J, Szöke K, Jaroszewicz J, Dentini M, Barbetta A, Brinchmann JE, Święszkowski W (2016)
    3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation
    Biofabrication, 8 (3), 035002
    DOI 10.1088/1758-5090/8/3/035002, PubMed 27431574
  4. Foldager CB, Bendtsen M, Berg LC, Brinchmann JE, Brittberg M, Bunger C, Canseco J, Chen L, Christensen BB, Colombier P, Deleuran BW, Edwards J, Elmengaard B, Farr J, Gatenholm B, Gomoll AH, Hui JH, Jakobsen RB, Joergensen NL, Kassem M, Koch T, Kold S, Krogsgaard MR, Lauridsen H, Le D et al. (2016)
    Aarhus Regenerative Orthopaedics Symposium (AROS)
    Acta Orthop, 87 (sup363), 1-5
    DOI 10.1080/17453674.2017.1297918, PubMed 28271925
  5. Karlsen TA, de Souza GA, Ødegaard B, Engebretsen L, Brinchmann JE (2016)
    microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis
    Mol Ther Nucleic Acids, 5 (10), e373
    DOI 10.1038/mtna.2016.64, PubMed 27727249

Publications 2015

  1. Hart ML, Izeta A, Herrera-Imbroda B, Amend B, Brinchmann JE (2015)
    Cell Therapy for Stress Urinary Incontinence
    Tissue Eng Part B Rev, 21 (4), 365-76
    DOI 10.1089/ten.TEB.2014.0627, PubMed 25789845
  2. Pullisaar H, Verket A, Szoke K, Tiainen H, Haugen HJ, Brinchmann JE, Reseland JE, Østrup E (2015)
    Alginate hydrogel enriched with enamel matrix derivative to target osteogenic cell differentiation in TiO2 scaffolds
    J Tissue Eng, 6, 2041731415575870
    DOI 10.1177/2041731415575870, PubMed 26090086
  3. Szöke K, Reinisch A, Østrup E, Reinholt FP, Brinchmann JE (2015)
    Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue
    Cytotherapy, 18 (2), 242-52
    DOI 10.1016/j.jcyt.2015.10.009, PubMed 26669908

Publications 2014

  1. Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE (2014)
    Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells
    Stem Cells, 32 (6), 1629-35
    DOI 10.1002/stem.1642, PubMed 24449344
  2. Jakobsen RB, Shahdadfar A, Reinholt FP, Brinchmann JE (2014)
    Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue (vol 18, pg 1407, 2010)
    Knee Surg. Sports Traumatol. Arthrosc., 22 (7), 1711-1714
  3. Jakobsen RB, Østrup E, Zhang X, Mikkelsen TS, Brinchmann JE (2014)
    Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling
    PLoS One, 9 (5), e96615
    DOI 10.1371/journal.pone.0096615, PubMed 24816923
  4. Klein G, Hart ML, Brinchmann JE, Rolauffs B, Stenzl A, Sievert KD, Aicher WK (2014)
    Mesenchymal stromal cells for sphincter regeneration
    Adv Drug Deliv Rev, 82-83, 123-36
    DOI 10.1016/j.addr.2014.10.026, PubMed 25451135
  5. Olderøy MØ, Lilledahl MB, Beckwith MS, Melvik JE, Reinholt F, Sikorski P, Brinchmann JE (2014)
    Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels
    PLoS One, 9 (3), e91662
    DOI 10.1371/journal.pone.0091662, PubMed 24626259
  6. Pullisaar H, Reseland JE, Haugen HJ, Brinchmann JE, Ostrup E (2014)
    Simvastatin coating of TiO₂ scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells
    Biochem Biophys Res Commun, 447 (1), 139-44
    DOI 10.1016/j.bbrc.2014.03.133, PubMed 24704451

Publications 2013

  1. Fernandes AM, Herlofsen SR, Karlsen TA, Küchler AM, Fløisand Y, Brinchmann JE (2013)
    Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage
    PLoS One, 8 (5), e62994
    DOI 10.1371/journal.pone.0062994, PubMed 23671648
  2. Herlofsen SR, Bryne JC, Høiby T, Wang L, Issner R, Zhang X, Coyne MJ, Boyle P, Gu H, Meza-Zepeda LA, Collas P, Mikkelsen TS, Brinchmann JE (2013)
    Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells
    BMC Genomics, 14, 105
    DOI 10.1186/1471-2164-14-105, PubMed 23414147
  3. Karlsen TA, Brinchmann JE (2013)
    Liposome delivery of microRNA-145 to mesenchymal stem cells leads to immunological off-target effects mediated by RIG-I
    Mol Ther, 21 (6), 1169-81
    DOI 10.1038/mt.2013.55, PubMed 23568258
  4. Karlsen TA, Jakobsen RB, Mikkelsen TS, Brinchmann JE (2013)
    microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN
    Stem Cells Dev, 23 (3), 290-304
    DOI 10.1089/scd.2013.0209, PubMed 24063364
  5. Rohban R, Reinisch A, Etchart N, Schallmoser K, Hofmann NA, Szoke K, Brinchmann JE, Bonyadi Rad E, Rohde E, Strunk D (2013)
    Identification of an effective early signaling signature during neo-vasculogenesis in vivo by ex vivo proteomic profiling
    PLoS One, 8 (6), e66909
    DOI 10.1371/journal.pone.0066909, PubMed 23826172
  6. Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
    Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Cancer Immunol Immunother, 62 (9), 1499-509
    DOI 10.1007/s00262-013-1453-3, PubMed 23817721

Publications 2012

  1. Otto Beitnes J, Oie E, Shahdadfar A, Karlsen T, Müller RM, Aakhus S, Reinholt FP, Brinchmann JE (2012)
    Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular function
    Cell Transplant, 21 (8), 1697-709
    DOI 10.3727/096368911X627462, PubMed 22410280
  2. Szöke K, Beckstrøm KJ, Brinchmann JE (2012)
    Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming
    Stem Cell Res, 9 (2), 135-42
    DOI 10.1016/j.scr.2012.05.006, PubMed 22721648
  3. Szöke K, Brinchmann JE (2012)
    Concise review: therapeutic potential of adipose tissue-derived angiogenic cells
    Stem Cells Transl Med, 1 (9), 658-67
    DOI 10.5966/sctm.2012-0069, PubMed 23197872

Publications 2011

  1. Beitnes JO, Lunde K, Brinchmann JE, Aakhus S (2011)
    Stem cells for cardiac repair in acute myocardial infarction
    Expert Rev Cardiovasc Ther, 9 (8), 1015-25
    DOI 10.1586/erc.11.108, PubMed 21878046
  2. Duggal S, Brinchmann JE (2011)
    Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells
    J Cell Physiol, 226 (11), 2908-15
    DOI 10.1002/jcp.22637, PubMed 21302288
  3. Herlofsen SR, Küchler AM, Melvik JE, Brinchmann JE (2011)
    Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in self-gelling alginate discs reveals novel chondrogenic signature gene clusters
    Tissue Eng Part A, 17 (7-8), 1003-13
    DOI 10.1089/ten.TEA.2010.0499, PubMed 21087199
  4. Karlsen TA, Mirtaheri P, Shahdadfar A, Fløisand Y, Brinchmann JE (2011)
    Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells
    J Cell Biochem, 112 (2), 684-93
    DOI 10.1002/jcb.22978, PubMed 21268090
  5. Szöke K, Beckstrøm KJ, Brinchmann JE (2011)
    Human adipose tissue as a source of cells with angiogenic potential
    Cell Transplant, 21 (1), 235-50
    DOI 10.3727/096368911X580518, PubMed 21669039

Publications 2010

  1. Karlsen TA, Shahdadfar A, Brinchmann JE (2010)
    Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype
    Tissue Eng Part C Methods, 17 (2), 219-27
    DOI 10.1089/ten.TEC.2010.0200, PubMed 20799885

Publications 2009

  1. Beitnes JO, Hopp E, Lunde K, Solheim S, Arnesen H, Brinchmann JE, Forfang K, Aakhus S (2009)
    Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
    Heart, 95 (24), 1983-9
    DOI 10.1136/hrt.2009.178913, PubMed 19833610
  2. Duggal S, Frønsdal KB, Szöke K, Shahdadfar A, Melvik JE, Brinchmann JE (2009)
    Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds
    Tissue Eng Part A, 15 (7), 1763-73
    DOI 10.1089/ten.tea.2008.0306, PubMed 19115828
  3. Hildrestrand GA, Duggal S, Bjørås M, Luna L, Brinchmann JE (2009)
    Modulation of DNA glycosylase activities in mesenchymal stem cells
    Exp Cell Res, 315 (15), 2558-67
    DOI 10.1016/j.yexcr.2009.05.017, PubMed 19477173
  4. Jakobsen RB, Shahdadfar A, Reinholt FP, Brinchmann JE (2009)
    Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue
    Knee Surg Sports Traumatol Arthrosc, 18 (10), 1407-16
    DOI 10.1007/s00167-009-1017-4, PubMed 20020100
  5. Koga H, Engebretsen L, Brinchmann JE, Muneta T, Sekiya I (2009)
    Mesenchymal stem cell-based therapy for cartilage repair: a review
    Knee Surg Sports Traumatol Arthrosc, 17 (11), 1289-97
    DOI 10.1007/s00167-009-0782-4, PubMed 19333576

Publications 2008

  1. Dahl JA, Duggal S, Coulston N, Millar D, Melki J, Shahdadfar A, Brinchmann JE, Collas P (2008)
    Genetic and epigenetic instability of human bone marrow mesenchymal stem cells expanded in autologous serum or fetal bovine serum
    Int J Dev Biol, 52 (8), 1033-42
    DOI 10.1387/ijdb.082663jd, PubMed 18956336
  2. Løken S, Jakobsen RB, Arøen A, Heir S, Shahdadfar A, Brinchmann JE, Engebretsen L, Reinholt FP (2008)
    Bone marrow mesenchymal stem cells in a hyaluronan scaffold for treatment of an osteochondral defect in a rabbit model
    Knee Surg Sports Traumatol Arthrosc, 16 (10), 896-903
    DOI 10.1007/s00167-008-0566-2, PubMed 18592218
  3. Shahdadfar A, Løken S, Dahl JA, Tunheim SH, Collas P, Reinholt FP, Engebretsen L, Brinchmann JE (2008)
    Persistence of collagen type II synthesis and secretion in rapidly proliferating human articular chondrocytes in vitro
    Tissue Eng Part A, 14 (12), 1999-2007
    DOI 10.1089/ten.tea.2007.0344, PubMed 18636947
  4. Wester T, Jørgensen JJ, Stranden E, Sandbaek G, Tjønnfjord G, Bay D, Kollerøs D, Kroese AJ, Brinchmann JE (2008)
    Treatment with autologous bone marrow mononuclear cells in patients with critical lower limb ischaemia. A pilot study
    Scand J Surg, 97 (1), 56-62
    DOI 10.1177/145749690809700108, PubMed 18450207

Publications 2007

  1. Brinchmann JE (2007)
    Expanding autologous multipotent mesenchymal bone marrow stromal cells
    J Neurol Sci, 265 (1-2), 127-30
    DOI 10.1016/j.jns.2007.05.006, PubMed 17560612
  2. Egeland T, Brinchmann JE (2007)
    The REPAIR-AMI and ASTAMI trials: cell isolation procedures
    Eur Heart J, 28 (17), 2174-5; author reply 2175
    DOI 10.1093/eurheartj/ehm240, PubMed 17673446
  3. Egeland T, Brinchmann JE (2007)
    Cell quality in the ASTAMI study
    Eur Heart J, 28 (17), 2172; author reply 2173-4
    DOI 10.1093/eurheartj/ehm125, PubMed 17675309

Publications 2006

  1. Boquest AC, Shahdadfar A, Brinchmann JE, Collas P (2006)
    Isolation of stromal stem cells from human adipose tissue
    Methods Mol Biol, 325, 35-46
    DOI 10.1385/1-59745-005-7:35, PubMed 16761717
  2. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T, Endresen K, Ilebekk A, Mangschau A, Fjeld JG, Smith HJ, Taraldsrud E, Grøgaard HK, Bjørnerheim R, Brekke M, Müller C, Hopp E, Ragnarsson A, Brinchmann JE, Forfang K (2006)
    Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
    N Engl J Med, 355 (12), 1199-209
    DOI 10.1056/NEJMoa055706, PubMed 16990383

Publications 2005

  1. Boquest AC, Shahdadfar A, Frønsdal K, Sigurjonsson O, Tunheim SH, Collas P, Brinchmann JE (2005)
    Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture
    Mol Biol Cell, 16 (3), 1131-41
    DOI 10.1091/mbc.e04-10-0949, PubMed 15635089
  2. Dalgaard J, Beckstrøm KJ, Jahnsen FL, Brinchmann JE (2005)
    Differential capability for phagocytosis of apoptotic and necrotic leukemia cells by human peripheral blood dendritic cell subsets
    J Leukoc Biol, 77 (5), 689-98
    DOI 10.1189/jlb.1204711, PubMed 15728242
  3. Hedfors IA, Beckstrøm KJ, Benati C, Bonini C, Brinchmann JE (2005)
    Retrovirus mediated gene transduction of human T-cell subsets
    Cancer Immunol Immunother, 54 (8), 759-68
    DOI 10.1007/s00262-004-0647-0, PubMed 15655695
  4. Kvale EØ, Dalgaard J, Lund-Johansen F, Rollag H, Farkas L, Midtvedt K, Jahnsen FL, Brinchmann JE, Olweus J (2005)
    CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection
    Blood, 107 (5), 2022-9
    DOI 10.1182/blood-2005-05-2016, PubMed 16269620
  5. Shahdadfar A, Frønsdal K, Haug T, Reinholt FP, Brinchmann JE (2005)
    In vitro expansion of human mesenchymal stem cells: choice of serum is a determinant of cell proliferation, differentiation, gene expression, and transcriptome stability
    Stem Cells, 23 (9), 1357-66
    DOI 10.1634/stemcells.2005-0094, PubMed 16081661

Publications 2003

  1. Dalgaard J, Beckstrøm KJ, Brinchmann JE (2003)
    Uptake of Apoptotic K562 Leukaemia Cells by Immature Dendritic Cells is Greatly Facilitated by Serum
    Scand J Immunol, 58 (5), 541-9
    DOI 10.1046/j.1365-3083.2003.01332.x, PubMed 14629626
  2. Hedfors IA, Brinchmann JE (2003)
    Polyclonal T-cell activation protocol stimulates preferential expansion of EBV-specific T-cell clones in vitro
    Cancer Immunol Immunother, 53 (5), 439-44
    DOI 10.1007/s00262-003-0462-z, PubMed 14624314
  3. Hedfors IA, Brinchmann JE (2003)
    Long-term proliferation and survival of in vitro-activated T cells is dependent on Interleukin-2 receptor signalling but not on the high-affinity IL-2R
    Scand J Immunol, 58 (5), 522-32
    DOI 10.1046/j.1365-3083.2003.01338.x, PubMed 14629624

Publications 2000

  1. Brinchmann JE (2000)
    Differential responses of T cell subsets: possible role in the immunopathogenesis of AIDS
    AIDS, 14 (12), 1689-700
    DOI 10.1097/00002030-200008180-00002, PubMed 10985304

Publications 1999

  1. Mugnaini EN, Egeland T, Spurkland A, Brinchmann JE (1999)
    The T cell receptor repertoire of CD8+CD28- T lymphocytes is dominated by expanded clones that persist over time
    Clin Exp Immunol, 117 (2), 298-303
    DOI 10.1046/j.1365-2249.1999.00980.x, PubMed 10444261
  2. Mugnaini EN, Egeland T, Syversen AM, Spurkland A, Brinchmann JE (1999)
    Molecular analysis of the complementarity determining region 3 of the human T cell receptor beta chain. Establishment of a reference panel of CDR3 lengths from phytohaemagglutinin activated lymphocytes
    J Immunol Methods, 223 (2), 207-16
    DOI 10.1016/s0022-1759(99)00004-6, PubMed 10089099
  3. Mugnaini EN, Haaheim LL, Sannes M, Brinchmann JE (1999)
    In vivo expansion coincident with excessive in vitro cell death within the memory subset of CD8+ T cells in HIV type 1 infection
    AIDS Res Hum Retroviruses, 15 (3), 265-72
    DOI 10.1089/088922299311448, PubMed 10052757
  4. Mugnaini EN, Syversen AM, Sannes M, Freng A, Brinchmann JE (1999)
    Normal CD4 T-cell receptor repertoire in tonsillar tissue despite perturbed repertoire in peripheral blood in HIV-1 infected individuals
    AIDS, 13 (18), 2507-13
    DOI 10.1097/00002030-199912240-00003, PubMed 10630519

Publications 1998

  1. Brinchmann JE, Røsok BI, Spurkland A (1998)
    Activation and proliferation of CD8+ T cells in lymphoid tissues of HIV-1-infected individuals in the absence of the high-affinity IL-2 receptor
    J Acquir Immune Defic Syndr Hum Retrovirol, 19 (4), 332-8
    DOI 10.1097/00042560-199812010-00003, PubMed 9833741
  2. Mugnaini EN, Spurkland A, Egeland T, Sannes M, Brinchmann JE (1998)
    Demonstration of identical expanded clones within both CD8+CD28+ and CD8+CD28- T cell subsets in HIV type 1-infected individuals
    Eur J Immunol, 28 (5), 1738-42
    DOI 10.1002/(SICI)1521-4141(199806)28:06<1745::AID-IMMU1745>3.0.CO;2-5, PubMed 9603481
  3. Reisaeter AV, Thorsby E, Brinchmann JE (1998)
    Allospecific helper T-lymphocyte repertoire in monozygotic twins
    Scand J Immunol, 47 (4), 381-7
    DOI 10.1046/j.1365-3083.1998.00308.x, PubMed 9600321
  4. Røsok BI, Brinchmann JE, Stent G, Bjerknes R, Voltersvik P, Olofsson J, Asjö B (1998)
    Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection
    AIDS Res Hum Retroviruses, 14 (18), 1635-43
    DOI 10.1089/aid.1998.14.1635, PubMed 9870316
  5. Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (1998)
    Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites
    J Biol Chem, 273 (8), 4539-46
    DOI 10.1074/jbc.273.8.4539, PubMed 9468509

Publications 1997

  1. Rosok B, Brinchmann JE, Voltersvik P, Olofsson J, Bostad L, Asjö B (1997)
    Correlates of latent and productive HIV type-1 infection in tonsillar CD4(+) T cells
    Proc Natl Acad Sci U S A, 94 (17), 9332-6
    DOI 10.1073/pnas.94.17.9332, PubMed 9256482
  2. Røsok B, Voltersvik P, Larsson BM, Albert J, Brinchmann JE, Asjö B (1997)
    CD8+ T cells from HIV type 1-seronegative individuals suppress virus replication in acutely infected cells
    AIDS Res Hum Retroviruses, 13 (1), 79-85
    DOI 10.1089/aid.1997.13.79, PubMed 8989430

Publications 1996

  1. Brinchmann JE, Janson CH, Klem LB, Haaheim LL, Spurkland A (1996)
    Strict adherence to a common rank order of T-cell receptor V beta usage in human leucocyte antigen disparate individuals
    Scand J Immunol, 44 (2), 179-84
    DOI 10.1046/j.1365-3083.1996.d01-294.x, PubMed 8711432
  2. Reisaeter AV, Brinchmann JE, Lundin KE, Thorsby E (1996)
    Monozygotic twins display differences in their allospecific cytotoxic T-cell repertoire
    Scand J Immunol, 44 (6), 638-42
    DOI 10.1046/j.1365-3083.1996.d01-357.x, PubMed 8972747
  3. Reisaeter AV, Thorsby E, Brinchmann JE (1996)
    Analysis of alloreactive helper T lymphocyte precursor frequencies. Influence of interleukin-2 produced by the stimulating cells
    J Immunol Methods, 189 (1), 65-72
    DOI 10.1016/0022-1759(95)00230-8, PubMed 8576581
  4. Røsok BI, Bostad L, Voltersvik P, Bjerknes R, Olofsson J, Asjö B, Brinchmann JE (1996)
    Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection
    AIDS, 10 (10), F35-8
    PubMed 8874620

Publications 1994

  1. Brinchmann JE, Dobloug JH, Heger BH, Haaheim LL, Sannes M, Egeland T (1994)
    Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations
    J Infect Dis, 169 (4), 730-8
    DOI 10.1093/infdis/169.4.730, PubMed 7907640
  2. Lundin KE, Brinchmann JE, Hansen T (1994)
    Interactions between staphylococcal superantigens and human T-cell clones are predominantly but not exclusively governed by their T-cell receptor V beta usage
    Scand J Immunol, 39 (4), 387-94
    DOI 10.1111/j.1365-3083.1994.tb03390.x, PubMed 8146598

Publications 1992

  1. Brinchmann JE (1992)
    [Factors influencing the development of the HIV pandemic]
    Tidsskr Nor Laegeforen, 112 (17), 2231-4
    PubMed 1523666
  2. Brinchmann JE (1992)
    [HIV pandemic--history, present, future]
    Tidsskr Nor Laegeforen, 112 (17), 2268-71
    PubMed 1523672
  3. Brinchmann JE, Gaudernack G, Thorsby E, Vartdal F (1992)
    Staphylococcal exotoxin superantigens induce human immunodeficiency virus type 1 expression in naturally infected CD4+ T cells
    J Virol, 66 (10), 5924-8
    PubMed 1356159

Publications 1991

  1. Brinchmann JE, Albert J, Vartdal F (1991)
    Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection
    J Virol, 65 (4), 2019-23
    PubMed 1672165
  2. Brinchmann JE, Gaudernack G, Vartdal F (1991)
    In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alpha
    J Acquir Immune Defic Syndr, 4 (5), 480-8
    PubMed 1673156
  3. Brinchmann JE, Vartdal F, Thorsby E, Bucher A, Frøland SS, Kittelsen P, Kristoffersen J, Baklien K (1991)
    [Quantification of T-lymphocyte subpopulations. Immunological marker in human immunodeficiency virus infections]
    Tidsskr Nor Laegeforen, 111 (4), 440-3
    PubMed 2006482

Publications 1990

  1. Brinchmann JE, Gaudernack G, Vartdal F (1990)
    CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitor
    J Immunol, 144 (8), 2961-6
    PubMed 1969879

Publications 1989

  1. Brinchmann JE, Gaudernack G, Thorsby E, Jonassen TO, Vartdal F (1989)
    Reliable isolation of human immunodeficiency virus from cultures of naturally infected CD4+ T cells
    J Virol Methods, 25 (3), 293-300
    DOI 10.1016/0166-0934(89)90056-6, PubMed 2573612
  2. Brinchmann JE, Leivestad T, Vartdal F (1989)
    Quantification of lymphocyte subsets based on positive immunomagnetic selection of cells directly from blood
    J Immunogenet, 16 (2), 177-83
    PubMed 2687388
  3. Brinchmann JE, Vartdal F, Thorsby E (1989)
    T lymphocyte subset changes in human immunodeficiency virus infection
    J Acquir Immune Defic Syndr, 2 (4), 398-403
    PubMed 2526872

Publications 1988

  1. Brinchmann JE, Vartdal F, Forset KL, Thorsby E (1988)
    Immunologic monitoring of rabbit antithymocyte globulin-treated transplant recipients: a comparison of serial E-RFC and immunomagnetic quantitation of CD2+ cells
    Transplant Proc, 20 (3), 390-1
    PubMed 3289168
  2. Brinchmann JE, Vartdal F, Forset KL, Thorsby E (1988)
    A comparison of serial E-RFC monitoring and immunomagnetic quantitation of CD2+ cells in RATG-treated transplant recipients
    Transplantation, 45 (4), 804-5
    PubMed 2895968
  3. Brinchmann JE, Vartdal F, Gaudernack G, Markussen G, Funderud S, Ugelstad J, Thorsby E (1988)
    Direct immunomagnetic quantification of lymphocyte subsets in blood
    Clin Exp Immunol, 71 (1), 182-6
    PubMed 3349645

Publications 1983

  1. Brinchmann JE, Haukås G (1983)
    [Unusual manifestations of syphilis]
    Tidsskr Nor Laegeforen, 103 (13), 1058-60
    PubMed 6879544
 
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