Publications published since 2010 from OUS - Bioinformatics Core Facility and Elixir Oslo node

88 publications found

Publications 2025

1. Ølnes ÅS, Teigen M, Laerdahl JK, Leren TP, Strøm TB, Bjune K (2025)
   Correction: Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
   PLoS One, 20 (9), e0332400
   DOI 10.1371/journal.pone.0332400, PubMed 40938802

Publications 2023

1. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
   Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
   Mol Oncol, 17 (11), 2432-2450
   DOI 10.1002/1878-0261.13514, PubMed 37622176
2. Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N (2023)
   Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
   iScience, 26 (4), 106448
   DOI 10.1016/j.isci.2023.106448, PubMed 37020951
3. Verleih M, Visnovska T, Nguinkal JA, Rebl A, Goldammer T, Andreassen R (2023)
   The Discovery and Characterization of Conserved and Novel miRNAs in the Different Developmental Stages and Organs of Pikeperch (Sander lucioperca)
   Int J Mol Sci, 25 (1)
   DOI 10.3390/ijms25010189, PubMed 38203361

Publications 2022

1. Chakraborty S, Woldemariam NT, Visnovska T, Rise ML, Boyce D, Santander J, Andreassen R (2022)
   Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
   Biology (Basel), 11 (1)
   DOI 10.3390/biology11010130, PubMed 35053128
2. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
   MirGeneDB 2.1: toward a complete sampling of all major animal phyla
   Nucleic Acids Res, 50 (D1), D204-D210
   DOI 10.1093/nar/gkab1101, PubMed 34850127
3. Przybyła W, Gjersvoll Paulsen KM, Mishra CK, Nygård S, Engebretsen S, Ruud E, Trøen G, Beiske K, Baumbusch LO (2022)
   Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
   PLoS One, 17 (8), e0273280
   DOI 10.1371/journal.pone.0273280, PubMed 36037157
4. Shwe A, Krasnov A, Visnovska T, Ramberg S, Østbye TK, Andreassen R (2022)
   Expression Analysis in Atlantic Salmon Liver Reveals miRNAs Associated with Smoltification and Seawater Adaptation
   Biology (Basel), 11 (5)
   DOI 10.3390/biology11050688, PubMed 35625416
5. Shwe A, Krasnov A, Visnovska T, Ramberg S, Østbye TK, Andreassen R (2022)
   Differential Expression of miRNAs and Their Predicted Target Genes Indicates That Gene Expression in Atlantic Salmon Gill Is Post-Transcriptionally Regulated by miRNAs in the Parr-Smolt Transformation and Adaptation to Sea Water
   Int J Mol Sci, 23 (15)
   DOI 10.3390/ijms23158831, PubMed 35955964
6. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
   Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
   Cancers (Basel), 14 (22)
   DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

1. Ferreira FA, Helmersen K, Visnovska T, Jørgensen SB, Aamot HV (2021)
   Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
   Microb Genom, 7 (4)
   DOI 10.1099/mgen.0.000557, PubMed 33885360
2. Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
   Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
   iScience, 24 (7), 102807
   DOI 10.1016/j.isci.2021.102807, PubMed 34337362
3. Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
   DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
   Atherosclerosis, 324, 123-132
   DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
4. Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
   Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
   Carcinogenesis, 42 (5), 685-693
   DOI 10.1093/carcin/bgab015, PubMed 33609362

Publications 2020

1. Ferrante L, Opdal SH, Nygård S, Vege Å, Rognum TO (2020)
   Gene expression profile in cases of infectious death in infancy
   Pediatr Res, 89 (3), 483-487
   DOI 10.1038/s41390-020-0896-4, PubMed 32299088
2. Ferrante L, Opdal SH, Nygaard V (2020)
   No association to sudden infant death syndrome detected by targeted amplicon sequencing of 24 genes
   Acta Paediatr, 109 (12), 2636-2640
   DOI 10.1111/apa.15295, PubMed 32271962
3. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
   Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
   Acta Oncol, 59 (7), 733-740
   DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
4. Woldemariam NT, Agafonov O, Sindre H, Høyheim B, Houston RD, Robledo D, Bron JE, Andreassen R (2020)
   miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
   Front Immunol, 11, 2113
   DOI 10.3389/fimmu.2020.02113, PubMed 33013890

Publications 2019

1. Brynildsen J, Petäjä L, Myhre PL, Lyngbakken MN, Nygård S, Stridsberg M, Christensen G, Ottesen AH, Pettilä V, Omland T, Røsjø H (2019)
   Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
   Crit Care Med, 47 (5), e412-e419
   DOI 10.1097/CCM.0000000000003670, PubMed 30730440
2. Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
   A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
   Transl Oncol, 12 (7), 951-958
   DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111
3. Forthun RB, Hovland R, Schuster C, Puntervoll H, Brodal HP, Namløs HM, Aasheim LB, Meza-Zepeda LA, Gjertsen BT, Knappskog S, Straume O (2019)
   ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab
   Sci Rep, 9 (1), 17471
   DOI 10.1038/s41598-019-53917-5, PubMed 31767937
4. Hagberg G, Fure B, Thommessen B, Ihle-Hansen H, Øksengård AR, Nygård S, Pendlebury ST, Beyer MK, Wyller TB, Ihle-Hansen H (2019)
   Predictors for Favorable Cognitive Outcome Post-Stroke: A-Seven-Year Follow-Up Study
   Dement Geriatr Cogn Disord, 48 (1-2), 45-55
   DOI 10.1159/000501850, PubMed 31461703
5. Ihle-Hansen H, Vigen T, Berge T, Hagberg G, Engedal K, Rønning OM, Thommessen B, Lyngbakken MN, Nygård S, Røsjø H, Tveit A, Ihle-Hansen H (2019)
   Carotid Atherosclerosis and Cognitive Function in a General Population Aged 63-65 Years: Data from the Akershus Cardiac Examination (ACE) 1950 Study
   J Alzheimers Dis, 70 (4), 1041-1049
   DOI 10.3233/JAD-190327, PubMed 31306128
6. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
   Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
   Cold Spring Harb Mol Case Stud, 5 (2)
   DOI 10.1101/mcs.a003566, PubMed 30862609
7. Malt EA, Juhasz K, Frengen A, Wangensteen T, Emilsen NM, Hansen B, Agafonov O, Nilsen HL (2019)
   Neuropsychiatric phenotype in relation to gene variants in the hemizygous allele in 3q29 deletion carriers: A case series
   Mol Genet Genomic Med, 7 (9), e889
   DOI 10.1002/mgg3.889, PubMed 31347308
8. Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T (2019)
   The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
   Sci Rep, 9 (1), 9206
   DOI 10.1038/s41598-019-45651-9, PubMed 31235849
9. Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
   PathTracer: High-sensitivity detection of differential pathway activity in tumours
   Sci Rep, 9 (1), 16332
   DOI 10.1038/s41598-019-52529-3, PubMed 31704995
10. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
11. Visnovska T, Biggs PJ, Schmeier S, Frizelle FA, Purcell RV (2019)
    Metagenomics and transcriptomics data from human colorectal cancer
    Sci Data, 6 (1), 116
    DOI 10.1038/s41597-019-0117-3, PubMed 31278253
12. Woldemariam NT, Agafonov O, Høyheim B, Houston RD, Taggart JB, Andreassen R (2019)
    Expanding the miRNA Repertoire in Atlantic Salmon; Discovery of IsomiRs and miRNAs Highly Expressed in Different Tissues and Developmental Stages
    Cells, 8 (1)
    DOI 10.3390/cells8010042, PubMed 30641951

Publications 2018

1. Aqrawi LA, Jensen JL, Øijordsbakken G, Ruus AK, Nygård S, Holden M, Jonsson R, Galtung HK, Skarstein K (2018)
   Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development
   Autoimmunity, 51 (3), 135-146
   DOI 10.1080/08916934.2018.1446525, PubMed 29504848
2. Brynildsen J, Petäjä L, Pettilä V, Nygård S, Vaara ST, Linko R, Okkonen M, Hagve TA, Soininen L, Suojaranta-Ylinen R, Lyngbakken MN, Omland T, Røsjø H (2018)
   The predictive value of NT-proBNP and hs-TnT for risk of death in cardiac surgical patients
   Clin Biochem, 53, 65-71
   DOI 10.1016/j.clinbiochem.2018.01.012, PubMed 29371002
3. Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2018)
   Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
   Br J Cancer, 118 (6), e11
   DOI 10.1038/bjc.2017.470, PubMed 29462127
4. Ihle-Hansen H, Vigen T, Ihle-Hansen H, Rønning OM, Berge T, Thommessen B, Lyngbakken MN, Orstad EB, Enger S, Nygård S, Røsjø H, Tveit A (2018)
   Prevalence of Carotid Plaque in a 63- to 65-Year-Old Norwegian Cohort From the General Population: The ACE (Akershus Cardiac Examination) 1950 Study
   J Am Heart Assoc, 7 (10)
   DOI 10.1161/JAHA.118.008562, PubMed 29739796
5. Tunsjø HS, Kalyanasundaram S, Charnock C, Leegaard TM, Moen AEF (2018)
   Challenges in the identification of methicillin-resistant Staphylococcus argenteus by routine diagnostics
   APMIS, 126 (6), 533-537
   DOI 10.1111/apm.12843, PubMed 29924450
6. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
   Sample-Index Misassignment Impacts Tumour Exome Sequencing
   Sci Rep, 8 (1), 5307
   DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

1. Andreassen R, Woldemariam NT, Egeland IØ, Agafonov O, Sindre H, Høyheim B (2017)
   Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
   BMC Genomics, 18 (1), 349
   DOI 10.1186/s12864-017-3741-3, PubMed 28472924
2. Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2017)
   Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
   Br J Cancer, 117 (11), 1656-1664
   DOI 10.1038/bjc.2017.346, PubMed 28972967
3. de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
   Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
   Liver Int, 37 (10), 1554-1561
   DOI 10.1111/liv.13402, PubMed 28267887
4. Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
   HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
   PLoS One, 12 (1), e0169074
   DOI 10.1371/journal.pone.0169074, PubMed 28045981
5. Myhre PL, Stridsberg M, Linko R, Okkonen M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Study Group (2017)
   Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
   Biomarkers, 22 (8), 775-781
   DOI 10.1080/1354750X.2016.1269200, PubMed 28049363
6. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
   Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
   ESMO Open, 2 (2), e000158
   DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
7. Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
   Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
   J Hepatol, 66 (6), 1214-1222
   DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472
8. Volchenkov R, Nygaard V, Sener Z, Skålhegg BS (2017)
   Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
   Front Immunol, 8, 698
   DOI 10.3389/fimmu.2017.00698, PubMed 28674533
9. Winther JA, Brynildsen J, Høiseth AD, Strand H, Følling I, Christensen G, Nygård S, Røsjø H, Omland T (2017)
   Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
   Respir Res, 18 (1), 184
   DOI 10.1186/s12931-017-0665-z, PubMed 29100503

Publications 2016

1. Andreassen R, Rangnes F, Sivertsen M, Chiang M, Tran M, Worren MM (2016)
   Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod (Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
   PLoS One, 11 (4), e0153324
   DOI 10.1371/journal.pone.0153324, PubMed 27128807
2. Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA (2016)
   NAD⁺ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
   Cell Metab, 24 (4), 566-581
   DOI 10.1016/j.cmet.2016.09.004, PubMed 27732836
3. Ferrante L, Rognum TO, Vege Å, Nygård S, Opdal SH (2016)
   Altered gene expression and possible immunodeficiency in cases of sudden infant death syndrome
   Pediatr Res, 80 (1), 77-84
   DOI 10.1038/pr.2016.45, PubMed 26959483
4. Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
   The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
   Gut, 66 (4), 611-619
   DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
5. Lyngbakken MN, Røsjø H, Holmen OL, Nygård S, Dalen H, Hveem K, Omland T (2016)
   Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study)
   Am J Cardiol, 118 (6), 816-821
   DOI 10.1016/j.amjcard.2016.06.043, PubMed 27453509
6. Lyngbakken MN, Skranes JB, de Lemos JA, Nygård S, Dalen H, Hveem K, Røsjø H, Omland T (2016)
   Impact of Smoking on Circulating Cardiac Troponin I Concentrations and Cardiovascular Events in the General Population: The HUNT Study (Nord-Trøndelag Health Study)
   Circulation, 134 (24), 1962-1972
   DOI 10.1161/CIRCULATIONAHA.116.023726, PubMed 27815376
7. Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ (2016)
   Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
   EBioMedicine, 8, 103-116
   DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423
8. Myhre PL, Ottesen AH, Okkonen M, Linko R, Stridsberg M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Laboratory Study Group (2016)
   Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
   Clin Chem, 62 (10), 1380-9
   DOI 10.1373/clinchem.2016.258764, PubMed 27540029
9. Røsjø H, Stridsberg M, Ottesen AH, Nygård S, Christensen G, Pettilä V, Linko R, Karlsson S, Varpula T, Ruokonen E, Omland T, FINNSEPSIS and FINNALI Study Groups (2016)
   Prognostic Value of Secretoneurin in Critically Ill Patients With Infections
   Crit Care Med, 44 (10), 1882-90
   DOI 10.1097/CCM.0000000000001832, PubMed 27414477
10. Tunsjø HS, Kalyanasundaram S, Worren MM, Leegaard TM, Moen AEF (2016)
    High frequency of occupied attB regions in Norwegian Staphylococcus aureus isolates supports a two-step MRSA screening algorithm
    Eur J Clin Microbiol Infect Dis, 36 (1), 65-74
    DOI 10.1007/s10096-016-2771-0, PubMed 27638009

Publications 2015

1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
   A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
   Nat Commun, 6, 10001
   DOI 10.1038/ncomms10001, PubMed 26647970
2. Landin MA, Nygård S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H (2015)
   Mapping the global mRNA transcriptome during development of the murine first molar
   Front Genet, 6, 47
   DOI 10.3389/fgene.2015.00047, PubMed 25852735
3. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
   CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
   PLoS One, 10 (2), e0117261
   DOI 10.1371/journal.pone.0117261, PubMed 25706641
4. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
   Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
   Genom Data, 5, 176-83
   DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
5. Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ (2015)
   The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
   Oncotarget, 6 (33), 34358-74
   DOI 10.18632/oncotarget.6024, PubMed 26452038
6. Omland T, de Lemos JA, Holmen OL, Dalen H, Benth JŠ, Nygård S, Hveem K, Røsjø H (2015)
   Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: the HUNT study
   Clin Chem, 61 (4), 646-56
   DOI 10.1373/clinchem.2014.234369, PubMed 25695851
7. Ricanek P, Lunde LK, Frye SA, Støen M, Nygård S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T (2015)
   Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
   Clin Exp Gastroenterol, 8, 49-67
   DOI 10.2147/CEG.S70119, PubMed 25624769
8. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
   BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
   Blood Cancer J, 5 (3), e299
   DOI 10.1038/bcj.2015.24, PubMed 25794135
9. Sevilla LM, Latorre V, Carceller E, Boix J, Vodák D, Mills IG, Pérez P (2015)
   Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes
   Mol Cell Endocrinol, 412, 281-9
   DOI 10.1016/j.mce.2015.05.015, PubMed 26001834
10. Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA (2015)
    Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells
    Oncotarget, 6 (28), 26192-215
    DOI 10.18632/oncotarget.4613, PubMed 26295306
11. Strøm TB, Laerdahl JK, Leren TP (2015)
    Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR
    Hum Mol Genet, 24 (20), 5836-44
    DOI 10.1093/hmg/ddv304, PubMed 26220972
12. Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
    Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
    Hepatology, 62 (1), 188-97
    DOI 10.1002/hep.27825, PubMed 25833813

Publications 2014

1. Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
   Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
   Immunogenetics, 67 (2), 73-84
   DOI 10.1007/s00251-014-0819-9, PubMed 25502872
2. Hillestad V, Espe EK, Cero F, Larsen KO, Sjaastad I, Nygård S, Skjønsberg OH, Christensen G (2014)
   IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
   Acta Physiol (Oxf), 213 (2), 492-504
   DOI 10.1111/apha.12376, PubMed 25182570
3. Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
   Identifying pathogenic processes by integrating microarray data with prior knowledge
   BMC Bioinformatics, 15, 115
   DOI 10.1186/1471-2105-15-115, PubMed 24758699
4. Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, Nygård S, Saugstad OD, Pietrzyk JJ (2014)
   Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
   Invest Ophthalmol Vis Sci, 55 (3), 1393-401
   DOI 10.1167/iovs.13-13159, PubMed 24458145
5. Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygård S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G (2014)
   Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart
   Life Sci, 97 (2), 145-54
   DOI 10.1016/j.lfs.2013.12.030, PubMed 24398041

Publications 2013

1. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
   Predicting physical interactions between protein complexes
   Mol Cell Proteomics, 12 (6), 1723-34
   DOI 10.1074/mcp.O112.019828, PubMed 23438732
2. Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
   The Genomic HyperBrowser: an analysis web server for genome-scale data
   Nucleic Acids Res, 41 (Web Server issue), W133-41
   DOI 10.1093/nar/gkt342, PubMed 23632163
3. Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
   Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
   PLoS One, 8 (6), e66165
   DOI 10.1371/journal.pone.0066165, PubMed 23824282
4. Vistnes M, Høiseth AD, Røsjø H, Nygård S, Pettersen E, Søyseth V, Hurlen P, Christensen G, Omland T (2013)
   Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
   Cytokine, 61 (3), 962-9
   DOI 10.1016/j.cyto.2013.01.006, PubMed 23415671
5. Wollen EJ, Sejersted Y, Wright MS, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Nygård S, Kwinta P, Pietrzyk JJ, Saugstad OD (2013)
   Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
   Pediatr Res, 74 (5), 536-44
   DOI 10.1038/pr.2013.140, PubMed 23999071
6. Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
   Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
   Pediatr Res, 75 (4), 517-26
   DOI 10.1038/pr.2013.249, PubMed 24375083

Publications 2012

1. Røsjø H, Nygård S, Kaukonen KM, Karlsson S, Stridsberg M, Ruokonen E, Pettilä V, Omland T, FINNSEPSIS Study Group (2012)
   Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study
   Intensive Care Med, 38 (5), 820-9
   DOI 10.1007/s00134-012-2546-8, PubMed 22491939
2. Røsjø H, Tamm NN, Kravdal G, Seferian KR, Høiseth AD, Nygård S, Badr P, Røysland R, Omland T (2012)
   Diagnostic utility of a single-epitope sandwich B-type natriuretic peptide assay in stable coronary artery disease: data from the Akershus Cardiac Examination (ACE) 1 Study
   Clin Biochem, 45 (16-17), 1269-75
   DOI 10.1016/j.clinbiochem.2012.05.010, PubMed 22609895
3. Røysland R, Kravdal G, Høiseth AD, Nygård S, Badr P, Hagve TA, Omland T, Røsjø H (2012)
   Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study
   Clin Sci (Lond), 122 (12), 599-606
   DOI 10.1042/CS20110557, PubMed 22239123
4. Skrbic B, Bjørnstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygård S, Bjørnstad S, Christensen G, Tønnessen T (2012)
   Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
   Matrix Biol, 32 (2), 133-42
   DOI 10.1016/j.matbio.2012.11.011, PubMed 23220517
5. Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
   Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
   J Appl Physiol (1985), 112 (8), 1372-82
   DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433

Publications 2011

1. Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
   Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
   PLoS One, 6 (12), e28302
   DOI 10.1371/journal.pone.0028302, PubMed 22164265
2. Sandve GK, Ferkingstad E, Nygård S (2011)
   Sequential Monte Carlo multiple testing
   Bioinformatics, 27 (23), 3235-41
   DOI 10.1093/bioinformatics/btr568, PubMed 21998154
3. Star B, Nederbragt AJ, Jentoft S, Grimholt U, Malmstrøm M, Gregers TF, Rounge TB, Paulsen J, Solbakken MH, Sharma A, Wetten OF, Lanzén A, Winer R, Knight J, Vogel JH, Aken B, Andersen O, Lagesen K, Tooming-Klunderud A, Edvardsen RB, Tina KG, Espelund M, Nepal C, Previti C, Karlsen BO et al. (2011)
   The genome sequence of Atlantic cod reveals a unique immune system
   Nature, 477 (7363), 207-10
   DOI 10.1038/nature10342, PubMed 21832995
4. Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
   Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
   PLoS One, 6 (4), e18668
   DOI 10.1371/journal.pone.0018668, PubMed 21533157

Publications 2010

1. Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
   Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
   Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
   DOI 10.1152/ajpheart.01155.2009, PubMed 20802136