Mona-Elisabeth Revheim's research group:

Functional and Molecular Imaging

 
Mona-Elisabeth Revheim<br>Group leader
Mona-Elisabeth Revheim
Group leader

The research group was founded in August 2012 to integrate expertise in functional, structural and molecular imaging research.

Research aims

Expanded knowledge of the pathogenesis behind diseases has led to the development of novel targeted therapies. Functional and molecular imaging modalities are promising for non-invasive diagnosis and evaluation of treatment response at an earlier time point than morphological imaging. The goals are to individualize diagnostic work-up and treatment, in order to optimize treatment outcome and minimize toxicity. The group focuses on:

  • clinical- and translational studies
  • how to optimize image quality and to improve accuracy of disease detection
  • in vivo tissue characterization and depiction of disease process
  • treatment response assessment
  • multimodality imaging
  • theranostic medicine

Current projects

  • Multimodal imaging in the characterization of tumors to assess tumor aggressiveness, diagnostic work-up and treatment response evaluation in prostate cancer, cervical cancer, breast cancer, sarcomas, spinal metastases, neuroendocrine tumors, GISTs, colorectal cancers, liver malignancies and lymphoma
  • Characterization of vascular inflammation inclusive vulnerability in atherosclerosis, treatment selection and treatment response evaluation using PET, MRI and US
  • Detection of early inflammatory response after cerebral/peripheral organ hypoxia and resuscitation with different levels of oxygen and to assess the inflammatory response after different neuroprotective treatment strategies using a new 18F-TSPO PET tracer
  • Radio-immunotherapy for treatment of relapsed CD37+ non-Hodgkin lymphoma (the Betalutin study) and Selective Internal Radiation Therapy (SIRT) with SIR-Spheres
     

Contact information, group leader

Mona-Elisabeth Revheim, MD, Associate professor
Dept. of Radiology and Nuclear Medicine,
Oslo University Hospital and University of Oslo
PO Box 4950 Nydalen,
NO-0424 Oslo, Norway,
Tel: +47 23070840, Fax: +47 23073837,
E-mail: monar@ous-hf.no