Torhild Garen

  • Coordinateur, NOSVAR
  • +47 23 07 39 01
Research topics ; clinical epidemiology
 

Publications 2023

Haukeland H, Moe SR, Brunborg C, Botea A, Damjanic N, Wivestad GÅ, Øvreås HK, Bøe TB, Orre A, Garen T, Molberg Ø, Lerang K (2023)
Declining Incidence of Systemic Lupus Erythematosus in Norway 1999-2017: Data From a Population Cohort Identified by International Classification of Diseases, 10th Revision Code and Verified by Classification
Arthritis Rheumatol (in press)
DOI 10.1002/art.42775, PubMed 38108106

Moe SR, Haukeland H, Brunborg C, Botea A, Damjanic N, Wivestad GÅ, Øvreås H, Bøe T, Orre A, Garen T, Lilleby V, Provan SA, Molberg Ø, Lerang K (2023)
Persisting mortality gap in systemic lupus erythematosus; a population-based study on juvenile- and adult-onset SLE in Norway 1999-2022
Rheumatology (Oxford) (in press)
DOI 10.1093/rheumatology/kead519, PubMed 37769251

Vikse J, Midtvedt Ø, Fevang BS, Garen T, Palm Ø, Wallenius M, Bakland G, Norheim KB, Molberg Ø, Hoffmann-Vold AM (2023)
Differential sensitivity of the 2020 revised comprehensive diagnostic criteria and the 2019 ACR/EULAR classification criteria across IgG4-related disease phenotypes: results from a Norwegian cohort
Arthritis Res Ther, 25 (1), 163
DOI 10.1186/s13075-023-03155-y, PubMed 37670401

Publications 2022

Didriksen H, Molberg Ø, Mehta A, Jordan S, Palchevskiy V, Fretheim H, Gude E, Ueland T, Brunborg C, Garen T, Midtvedt Ø, Andreassen AK, Lund-Johansen F, Distler O, Belperio J, Hoffmann-Vold AM (2022)
Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension
Front Immunol, 13, 991743
DOI 10.3389/fimmu.2022.991743, PubMed 36211384

Tennøe AH, Murbræch K, Didriksen H, Ueland T, Palchevskiy V, Weigt SS, Fretheim H, Midtvedt Ø, Garen T, Brunborg C, Aukrust P, Molberg Ø, Belperio JA, Hoffmann-Vold AM (2022)
Serum markers of cardiac complications in a systemic sclerosis cohort
Sci Rep, 12 (1), 4661
DOI 10.1038/s41598-022-08815-8, PubMed 35304587

van Leeuwen NM, Boonstra M, Fretheim H, Brunborg C, Midtvedt Ø, Garen T, Molberg Ø, Huizinga TWJ, de Vries-Bouwstra JK, Hoffman-Vold AM (2022)
Gastrointestinal symptom severity and progression in systemic sclerosis
Rheumatology (Oxford), 61 (10), 4024-4034
DOI 10.1093/rheumatology/keac118, PubMed 35238377

Publications 2021

Didriksen H, Molberg Ø, Fretheim H, Gude E, Jordan S, Brunborg C, Palchevskiy V, Garen T, Midtvedt Ø, Andreassen AK, Distler O, Belperio J, Hoffmann-Vold AM (2021)
Association of Lymphangiogenic Factors With Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 73 (7), 1277-1287
DOI 10.1002/art.41665, PubMed 33497027

Publications 2020

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Molberg Ø, Hoffmann-Vold AM (2020)
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Rheumatology (Oxford), 59 (10), 2920-2929
DOI 10.1093/rheumatology/keaa026, PubMed 32097470

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

Publications 2019

Elhai M, Hoffmann-Vold AM, Avouac J, Pezet S, Cauvet A, Leblond A, Fretheim H, Garen T, Kuwana M, Molberg Ø, Allanore Y (2019)
Performance of Candidate Serum Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease
Arthritis Rheumatol, 71 (6), 972-982
DOI 10.1002/art.40815, PubMed 30624031

Garen T, Lerang K, Hoffmann-Vold AM, Andersson H, Midtvedt Ø, Brunborg C, Kilian K, Gudbrandsson B, Gunnarsson R, Norby G, Chaudhary A, Thoen J, Forseth KØ, Fresjar K, Førre Ø, Haugen M, Haga HJ, Gran JT, Gilboe IM, Molberg Ø, Palm Ø (2019)
Mortality and causes of death across the systemic connective tissue diseases and the primary systemic vasculitides
Rheumatology (Oxford), 58 (2), 313-320
DOI 10.1093/rheumatology/key285, PubMed 30281089

Hoffmann-Vold AM, Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Lund MB, Aaløkken TM, Molberg Ø (2019)
Tracking Impact of Interstitial Lung Disease in Systemic Sclerosis in a Complete Nationwide Cohort
Am J Respir Crit Care Med, 200 (10), 1258-1266
DOI 10.1164/rccm.201903-0486OC, PubMed 31310156

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Midtvedt Ø, Garen T, Dalen H, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2019)
Systolic Dysfunction in Systemic Sclerosis: Prevalence and Prognostic Implications
ACR Open Rheumatol, 1 (4), 258-266
DOI 10.1002/acr2.1037, PubMed 31777802

Publications 2018

Hoffmann-Vold AM, Fretheim H, Midtvedt Ø, Kilian K, Angelshaug M, Chaudhary A, Gunnarsson R, Brunborg C, Garen T, Andreassen AK, Gude E, Molberg Ø (2018)
Frequencies of borderline pulmonary hypertension before and after the DETECT algorithm: results from a prospective systemic sclerosis cohort
Rheumatology (Oxford), 57 (3), 480-487
DOI 10.1093/rheumatology/kex435, PubMed 29237073

Hoffmann-Vold AM, Hesselstrand R, Fretheim H, Ueland T, Andreassen AK, Brunborg C, Palchevskiy V, Midtvedt Ø, Garen T, Aukrust P, Belperio JA, Molberg Ø (2018)
CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 70 (10), 1644-1653
DOI 10.1002/art.40534, PubMed 29687634

Hoffmann-Vold AM, Weigt SS, Palchevskiy V, Volkmann E, Saggar R, Li N, Midtvedt Ø, Lund MB, Garen T, Fishbein MC, Ardehali A, Ross DJ, Ueland T, Aukrust P, Lynch JP, Elashoff RM, Molberg Ø, Belperio JA (2018)
Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis
PLoS One, 13 (11), e0206545
DOI 10.1371/journal.pone.0206545, PubMed 30457999

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Garen T, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2018)
Left Ventricular Diastolic Dysfunction Predicts Mortality in Patients With Systemic Sclerosis
J Am Coll Cardiol, 72 (15), 1804-1813
DOI 10.1016/j.jacc.2018.07.068, PubMed 30286924

Publications 2017

Andersson H, Kirkhus E, Garen T, Walle-Hansen R, Merckoll E, Molberg Ø (2017)
Comparative analyses of muscle MRI and muscular function in anti-synthetase syndrome patients and matched controls: a cross-sectional study
Arthritis Res Ther, 19 (1), 17
DOI 10.1186/s13075-017-1219-y, PubMed 28122635

Gudbrandsson B, Wallenius M, Garen T, Henriksen T, Molberg Ø, Palm Ø (2017)
Takayasu Arteritis and Pregnancy: A Population-Based Study on Outcomes and Mother/Child-Related Concerns
Arthritis Care Res (Hoboken), 69 (9), 1384-1390
DOI 10.1002/acr.23146, PubMed 27813289

Hoffmann-Vold AM, Midtvedt Ø, Tennøe AH, Garen T, Lund MB, Aaløkken TM, Andreassen AK, Elhage F, Brunborg C, Taraldsrud E, Molberg Ø (2017)
Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort
J Rheumatol, 44 (4), 459-465
DOI 10.3899/jrheum.160867, PubMed 28089974

Publications 2016

Andersson H, Aaløkken TM, Günther A, Mynarek GK, Garen T, Lund MB, Molberg Ø (2016)
Pulmonary Involvement in the Antisynthetase Syndrome: A Comparative Cross-sectional Study
J Rheumatol, 43 (6), 1107-13
DOI 10.3899/jrheum.151067, PubMed 27036381

Gudbrandsson B, Molberg Ø, Garen T, Palm Ø (2016)
Prevalence, Incidence, and Disease Characteristics of Takayasu Arteritis by Ethnic Background: Data From a Large, Population-Based Cohort Resident in Southern Norway
Arthritis Care Res (Hoboken), 69 (2), 278-285
DOI 10.1002/acr.22931, PubMed 27159262

Hoffmann-Vold AM, Tennøe AH, Garen T, Midtvedt Ø, Abraityte A, Aaløkken TM, Lund MB, Brunborg C, Aukrust P, Ueland T, Molberg Ø (2016)
High Level of Chemokine CCL18 Is Associated With Pulmonary Function Deterioration, Lung Fibrosis Progression, and Reduced Survival in Systemic Sclerosis
Chest, 150 (2), 299-306
DOI 10.1016/j.chest.2016.03.004, PubMed 26997242

Palm Ø, Ueland T, Garen T, Michelsen AE, Reiseter S, Aukrust P, Aaløkken TM, Molberg Ø (2016)
Endostatin is higher and associated with pulmonary involvement in primary Sjögren's syndrome
Clin Exp Rheumatol, 34 (4), 690-3
PubMed 27214260

Publications 2015

Andersson H, Sem M, Lund MB, Aaløkken TM, Günther A, Walle-Hansen R, Garen T, Molberg Ø (2015)
Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease
Rheumatology (Oxford), 54 (8), 1420-8
DOI 10.1093/rheumatology/kev004, PubMed 25740830

Dobloug GC, Garen T, Brunborg C, Gran JT, Molberg Ø (2015)
Survival and cancer risk in an unselected and complete Norwegian idiopathic inflammatory myopathy cohort
Semin Arthritis Rheum, 45 (3), 301-8
DOI 10.1016/j.semarthrit.2015.06.005, PubMed 26190563

Gunnarsson R, El-Hage F, Aaløkken TM, Reiseter S, Lund MB, Garen T, Norwegian MCTD study group, Molberg Ø (2015)
Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease
Rheumatology (Oxford), 55 (1), 103-8
DOI 10.1093/rheumatology/kev300, PubMed 26320136

Hoffmann-Vold AM, Aaløkken TM, Lund MB, Garen T, Midtvedt Ø, Brunborg C, Gran JT, Molberg Ø (2015)
Predictive value of serial high-resolution computed tomography analyses and concurrent lung function tests in systemic sclerosis
Arthritis Rheumatol, 67 (8), 2205-12
DOI 10.1002/art.39166, PubMed 25916462

Reiseter S, Molberg Ø, Gunnarsson R, Lund MB, Aalokken TM, Aukrust P, Ueland T, Garen T, Brunborg C, Michelsen A, Abraityte A, Hoffmann-Vold AM (2015)
Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
Arthritis Res Ther, 17 (1), 231
DOI 10.1186/s13075-015-0756-5, PubMed 26315510

Publications 2014

Dobloug C, Garen T, Bitter H, Stjärne J, Stenseth G, Grøvle L, Sem M, Gran JT, Molberg Ø (2014)
Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort
Ann Rheum Dis, 74 (8), 1551-6
DOI 10.1136/annrheumdis-2013-205127, PubMed 24695011

Dobloug GC, Antal EA, Sveberg L, Garen T, Bitter H, Stjärne J, Grøvle L, Gran JT, Molberg Ø (2014)
High prevalence of inclusion body myositis in Norway; a population-based clinical epidemiology study
Eur J Neurol, 22 (4), 672-e41
DOI 10.1111/ene.12627, PubMed 25530508

Flåm ST, Gunnarsson R, Garen T, Norwegian MCTD Study Group, Lie BA, Molberg Ø (2014)
The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases
Rheumatology (Oxford), 54 (3), 528-35
DOI 10.1093/rheumatology/keu310, PubMed 25187641

Haugeberg G, Helgetveit KB, Førre Ø, Garen T, Sommerseth H, Prøven A (2014)
Generalized bone loss in early rheumatoid arthritis patients followed for ten years in the biologic treatment era
BMC Musculoskelet Disord, 15, 289
DOI 10.1186/1471-2474-15-289, PubMed 25182527

Hoffmann-Vold AM, Gunnarsson R, Garen T, Midtvedt Ø, Molberg Ø (2014)
Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in large, well-defined cohorts of SSc and mixed connective tissue disease
J Rheumatol, 42 (1), 60-3
DOI 10.3899/jrheum.140047, PubMed 25274890

Publications 2013

Gunnarsson R, Andreassen AK, Molberg Ø, Lexberg ÅS, Time K, Dhainaut AS, Bertelsen LT, Palm Ø, Irgens K, Becker-Merok A, Nordeide JL, Johnsen V, Pedersen S, Prøven A, Garabet LS, Garen T, Aaløkken TM, Gilboe IM, Gran JT (2013)
Prevalence of pulmonary hypertension in an unselected, mixed connective tissue disease cohort: results of a nationwide, Norwegian cross-sectional multicentre study and review of current literature
Rheumatology (Oxford), 52 (7), 1208-13
DOI 10.1093/rheumatology/kes430, PubMed 23407386

Hoffmann-Vold AM, Molberg Ø, Midtvedt Ø, Garen T, Gran JT (2013)
Survival and causes of death in an unselected and complete cohort of Norwegian patients with systemic sclerosis
J Rheumatol, 40 (7), 1127-33
DOI 10.3899/jrheum.121390, PubMed 23637316

Publications 2012

Hoffmann-Vold AM, Midtvedt Ø, Molberg Ø, Garen T, Gran JT (2012)
Prevalence of systemic sclerosis in south-east Norway
Rheumatology (Oxford), 51 (9), 1600-5
DOI 10.1093/rheumatology/kes076, PubMed 22539477

Lerang K, Gilboe I, Garen T, Thelle DS, Gran JT (2012)
High incidence and prevalence of systemic lupus erythematosus in Norway
Lupus, 21 (12), 1362-9
DOI 10.1177/0961203312458168, PubMed 22914817

Palm O, Garen T, Berge Enger T, Jensen JL, Lund MB, Aaløkken TM, Gran JT (2012)
Clinical pulmonary involvement in primary Sjogren's syndrome: prevalence, quality of life and mortality--a retrospective study based on registry data
Rheumatology (Oxford), 52 (1), 173-9
DOI 10.1093/rheumatology/kes311, PubMed 23192906

Publications 2011

Enger TB, Palm Ø, Garen T, Sandvik L, Jensen JL (2011)
Oral distress in primary Sjögren's syndrome: implications for health-related quality of life
Eur J Oral Sci, 119 (6), 474-80
DOI 10.1111/j.1600-0722.2011.00891.x, PubMed 22112034

Staalesen Strumse YA, Nordvåg BY, Stanghelle JK, Røisland M, Winther A, Pajunen PA, Garen T, Flatø B (2011)
Efficacy of rehabilitation for patients with ankylosing spondylitis: comparison of a four-week rehabilitation programme in a Mediterranean and a Norwegian setting
J Rehabil Med, 43 (6), 534-42
DOI 10.2340/16501977-0804, PubMed 21491073

Publications 2009

Staalesen Strumse YA, Nordvag BY, Stanghelle JK, Røsland M, Winther A, Pajunen PA, Garen T, Flatø B (2009)
The efficacy of rehabilitation for patients with rheumatoid arthritis: comparison between a 4-week rehabilitation programme in a warm and cold climate
Scand J Rheumatol, 38 (1), 28-37
DOI 10.1080/03009740802304549, PubMed 18728936

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