PubMed registered articles Intracellular Transport group

Publications published since 1976 from OUS - Intracellular transport (Sandvig)

367 publications found

Publications 2021

  1. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  2. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  3. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  4. Kosanović M, Llorente A, Glamočlija S, Valdivielso JM, Bozic M (2021)
    Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
    Int J Mol Sci, 22 (8)
    DOI 10.3390/ijms22083887, PubMed 33918699
  5. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
    DOI 10.3390/nano11051140, PubMed 33924869
  6. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035

Publications 2020

  1. Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
    Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
    Cell Mol Life Sci, 78 (3), 985-1009
    DOI 10.1007/s00018-020-03551-6, PubMed 32447426
  2. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B, 8 (31), 6710-6738
    DOI 10.1039/d0tb00861c, PubMed 32627783
  3. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  4. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  5. Skotland T, Kavaliauskiene S, Sandvig K (2020)
    The role of lipid species in membranes and cancer-related changes
    Cancer Metastasis Rev, 39 (2), 343-360
    DOI 10.1007/s10555-020-09872-z, PubMed 32314087
  6. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev, 159, 308-321
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  7. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  8. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  9. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  10. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975
  11. Tsjokajev A, Røberg-Larsen H, Wilson SR, Dyve Lingelem AB, Skotland T, Sandvig K, Lundanes E (2020)
    Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
    J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
    DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370
  12. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033
  13. Welsh JA, van der Pol E, Bettin BA, Carter DRF, Hendrix A, Lenassi M, Langlois MA, Llorente A, van de Nes AS, Nieuwland R, Tang V, Wang L, Witwer KW, Jones JC (2020)
    Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
    J Extracell Vesicles, 9 (1), 1816641
    DOI 10.1080/20013078.2020.1816641, PubMed 33062218

Publications 2019

  1. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  2. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
    The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
    J Pharmacol Exp Ther, 370 (3), 581-592
    DOI 10.1124/jpet.119.258012, PubMed 30940695
  3. Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
    Int J Nanomedicine, 14, 6269-6285
    DOI 10.2147/IJN.S208938, PubMed 31496685
  4. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963
  5. Skotland T, Sandvig K (2019)
    The role of PS 18:0/18:1 in membrane function
    Nat Commun, 10 (1), 2752
    DOI 10.1038/s41467-019-10711-1, PubMed 31227693
  6. Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
    Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Toxins (Basel), 11 (6)
    DOI 10.3390/toxins11060350, PubMed 31216687
  7. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074

Publications 2018

  1. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  2. Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
    Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Cell Commun Signal, 16 (1), 17
    DOI 10.1186/s12964-018-0229-y, PubMed 29690889
  3. Sandvig K, Kavaliauskiene S, Skotland T (2018)
    Clathrin-independent endocytosis: an increasing degree of complexity
    Histochem Cell Biol, 150 (2), 107-118
    DOI 10.1007/s00418-018-1678-5, PubMed 29774430
  4. Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
    Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
    J Lipid Res, 60 (1), 9-18
    DOI 10.1194/jlr.R084343, PubMed 30076207
  5. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
    J Extracell Vesicles, 7 (1), 1535750
    DOI 10.1080/20013078.2018.1535750, PubMed 30637094

Publications 2017

  1. Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
    Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
    Traffic, 18 (3), 176-191
    DOI 10.1111/tra.12468, PubMed 28067430
  2. Boye E, Skotland T, Østerud B, Nissen-Meyer J (2017)
    Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
    EMBO Rep, 18 (3), 351-354
    DOI 10.15252/embr.201643540, PubMed 28167676
  3. Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
    Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
    Sci Total Environ, 610-611, 972-982
    DOI 10.1016/j.scitotenv.2017.08.115, PubMed 28838034
  4. Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    BMC Cancer, 17 (1), 730
    DOI 10.1186/s12885-017-3737-z, PubMed 29121858
  5. Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
    Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
    ChemMedChem, 12 (8), 613-620
    DOI 10.1002/cmdc.201700108, PubMed 28334511
  6. Hessvik NP, Llorente A (2017)
    Current knowledge on exosome biogenesis and release
    Cell Mol Life Sci, 75 (2), 193-208
    DOI 10.1007/s00018-017-2595-9, PubMed 28733901
  7. Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
    PtdIns3P controls mTORC1 signaling through lysosomal positioning
    J Cell Biol, 216 (12), 4217-4233
    DOI 10.1083/jcb.201611073, PubMed 29030394
  8. Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
    Protection against Shiga Toxins
    Toxins (Basel), 9 (2)
    DOI 10.3390/toxins9020044, PubMed 28165371
  9. Labieniec-Watala M, Szwed M, Hertel J, Wisnik E (2017)
    Low Concentrations of Cationic PAMAM Dendrimers Affect Lymphocyte Respiration in In vitro Studies
    Curr Pharm Biotechnol, 18 (2), 150-157
    DOI 10.2174/1389201017666161229153018, PubMed 28034293
  10. Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
    Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
    PLoS One, 12 (1), e0170716
    DOI 10.1371/journal.pone.0170716, PubMed 28114329
  11. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358
  12. Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
    A novel community driven software for functional enrichment analysis of extracellular vesicles data
    J Extracell Vesicles, 6 (1), 1321455
    DOI 10.1080/20013078.2017.1321455, PubMed 28717418
  13. Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
    A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
    Biochem Biophys Res Commun, 495 (2), 1930-1935
    DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
  14. Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
    Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
    Exp Cell Res, 357 (1), 67-78
    DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044
  15. Skotland T (2017)
    Injection of nanoparticles into cloven-hoof animals: Asking for trouble
    Theranostics, 7 (19), 4877-4878
    DOI 10.7150/thno.22420, PubMed 29187910
  16. Skotland T, Sandvig K, Llorente A (2017)
    Lipids in exosomes: Current knowledge and the way forward
    Prog Lipid Res, 66, 30-41
    DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
  17. Sulheim E, Iversen TG, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, Hatletveit AR, Wågbø AM, Sundan A, Skotland T, Sandvig K, Mørch Ý (2017)
    Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
    Int J Mol Sci, 18 (11)
    DOI 10.3390/ijms18112454, PubMed 29156588
  18. Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
    A vital sugar code for ricin toxicity
    Cell Res, 27 (11), 1351-1364
    DOI 10.1038/cr.2017.116, PubMed 28925387
  19. Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
    Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
    J Extracell Vesicles, 6 (1), 1344087
    DOI 10.1080/20013078.2017.1344087, PubMed 28804597

Publications 2016

  1. Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
    Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
    Sci Rep, 6, 30336
    DOI 10.1038/srep30336, PubMed 27458147
  2. Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
    Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
    Oncotarget, 7 (18), 25443-60
    DOI 10.18632/oncotarget.8327, PubMed 27029001
  3. Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
    Mol Cancer, 15 (1), 41
    DOI 10.1186/s12943-016-0523-5, PubMed 27189160
  4. Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
    Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
    ACS Nano, 10 (4), 3886-99
    DOI 10.1021/acsnano.5b08015, PubMed 26978483
  5. Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
    A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
    PLoS One, 11 (6), e0156893
    DOI 10.1371/journal.pone.0156893, PubMed 27300140
  6. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  7. Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
    Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
    Oncotarget, 7 (48), 79885-79900
    DOI 10.18632/oncotarget.13089, PubMed 27829218
  8. Li Y, Hessvik NP, Danbolt NC, Holen T (2016)
    A large-scale quantitative EM study on activation of olfactory glands shows no effect of cholinergic agents
    Microscopy (Oxf), 65 (5), 438-443
    DOI 10.1093/jmicro/dfw028, PubMed 27460022
  9. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
    Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
    Data Brief, 7, 1171-1174
    DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
  10. Skotland T (2016)
    How organizers of scientific meetings and journal editors could facilitate transfer of nanomedicine into the clinic
    Eur. J. Nanomed., 8 (1), 61-63
  11. Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
    Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
    Eur J Cancer, 70, 122-132
    DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
  12. Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
    Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
    J Mol Biol, 428 (24 Pt A), 4856-4866
    DOI 10.1016/j.jmb.2016.06.013, PubMed 27363608
  13. Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
    The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
    Oncotarget, 7 (52), 86871-86888
    DOI 10.18632/oncotarget.13508, PubMed 27894086
  14. Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
    Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
    Eur J Pharm Sci, 98, 80-85
    DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330
  15. Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
    Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
    Sci Rep, 6, 22721
    DOI 10.1038/srep22721, PubMed 26949061

Publications 2015

  1. Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
    Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
    PLoS One, 10 (5), e0129214
    DOI 10.1371/journal.pone.0129214, PubMed 26017782
  2. Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
    Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
    Autophagy, 11 (3), 460-71
    DOI 10.1080/15548627.2015.1009797, PubMed 25749095
  3. Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
    Novel Furin Inhibitors with Potent Anti-infectious Activity
    ChemMedChem, 10 (7), 1218-31
    DOI 10.1002/cmdc.201500103, PubMed 25974265
  4. Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
    Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
    Biochem J, 470 (1), 23-37
    DOI 10.1042/BJ20141562, PubMed 26251444
  5. Klokk TI, Kavaliauskiene S, Sandvig K (2015)
    Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
    Cell Mol Life Sci, 73 (6), 1301-16
    DOI 10.1007/s00018-015-2049-1, PubMed 26407609
  6. Kymre L, Simm R, Skotland T, Sandvig K (2015)
    Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
    Pathog Dis, 73 (9), ftv083
    DOI 10.1093/femspd/ftv083, PubMed 26443836
  7. Le Guyon S, Simm R, Rehn M, Römling U (2015)
    Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium
    Environ Microbiol, 17 (4), 1310-20
    DOI 10.1111/1462-2920.12580, PubMed 25059628
  8. Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
    Identification of prostate cancer biomarkers in urinary exosomes
    Oncotarget, 6 (30), 30357-76
    DOI 10.18632/oncotarget.4851, PubMed 26196085
  9. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
    Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
    Biochim Biophys Acta, 1858 (2), 281-8
    DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
  10. Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
    Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
    Molecules, 20 (7), 13313-23
    DOI 10.3390/molecules200713313, PubMed 26205056
  11. Słomińska-Wojewódzka M, Sandvig K (2015)
    The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
    Molecules, 20 (6), 9816-46
    DOI 10.3390/molecules20069816, PubMed 26023941
  12. Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
    Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
    BMC Cell Biol, 16, 1
    DOI 10.1186/s12860-015-0047-7, PubMed 25655076
  13. Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
    Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
    Exp Cell Res, 333 (1), 21-38
    DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
  14. Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
    Biological properties of extracellular vesicles and their physiological functions
    J Extracell Vesicles, 4, 27066
    DOI 10.3402/jev.v4.27066, PubMed 25979354

Publications 2014

  1. Asp N, Pust S, Sandvig K (2014)
    Flotillin depletion affects ErbB protein levels in different human breast cancer cells
    Biochim Biophys Acta, 1843 (9), 1987-96
    DOI 10.1016/j.bbamcr.2014.04.013, PubMed 24747692
  2. Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
    The ether lipid precursor hexadecylglycerol protects against Shiga toxins
    Cell Mol Life Sci, 71 (21), 4285-300
    DOI 10.1007/s00018-014-1624-1, PubMed 24740796
  3. Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
    The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
    Biochem Biophys Res Commun, 447 (4), 586-9
    DOI 10.1016/j.bbrc.2014.04.043, PubMed 24747075
  4. Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
    LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
    Traffic, 15 (12), 1390-405
    DOI 10.1111/tra.12227, PubMed 25216107
  5. Kvalvaag AS, Pust S, Sandvig K (2014)
    Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
    Commun Integr Biol, 7 (1), e28129
    DOI 10.4161/cib.28129, PubMed 24778763
  6. Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
    Regulation of exosome release by glycosphingolipids and flotillins
    FEBS J, 281 (9), 2214-27
    DOI 10.1111/febs.12775, PubMed 24605801
  7. Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
    The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
    J Biol Chem, 290 (7), 4225-37
    DOI 10.1074/jbc.M114.593962, PubMed 25519911
  8. Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
    Lipid requirements for entry of protein toxins into cells
    Prog Lipid Res, 54, 1-13
    DOI 10.1016/j.plipres.2014.01.001, PubMed 24462587
  9. Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
    Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
    Future Microbiol, 9 (11), 1261-82
    DOI 10.2217/fmb.14.88, PubMed 25437188
  10. Skotland T, Iversen TG, Sandvig K (2014)
    Development of nanoparticles for clinical use
    Nanomedicine (Lond), 9 (9), 1295-9
    DOI 10.2217/nnm.14.81, PubMed 25204821
  11. Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K (2014)
    The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
    Biochem J, 457 (3), 485-96
    DOI 10.1042/BJ20130155, PubMed 24200403
  12. Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
    Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
    Toxicology, 326, 119-29
    DOI 10.1016/j.tox.2014.10.009, PubMed 25456271
  13. Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
    Antibody-mediated inhibition of ricin toxin retrograde transport
    mBio, 5 (2), e00995
    DOI 10.1128/mBio.00995-13, PubMed 24713323

Publications 2013

  1. Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
    The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
    PLoS One, 8 (9), e75904
    DOI 10.1371/journal.pone.0075904, PubMed 24098742
  2. Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
    BiP negatively affects ricin transport
    Toxins (Basel), 5 (5), 969-82
    DOI 10.3390/toxins5050969, PubMed 23666197
  3. Hessvik NP, Sandvig K, Llorente A (2013)
    Exosomal miRNAs as Biomarkers for Prostate Cancer
    Front Genet, 4, 36
    DOI 10.3389/fgene.2013.00036, PubMed 23519132
  4. Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
    Cell density-induced changes in lipid composition and intracellular trafficking
    Cell Mol Life Sci, 71 (6), 1097-116
    DOI 10.1007/s00018-013-1441-y, PubMed 23921715
  5. Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
    The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
    Traffic, 14 (7), 839-52
    DOI 10.1111/tra.12077, PubMed 23593995
  6. Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
    Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
    Biochim Biophys Acta, 1831 (7), 1302-9
    DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871
  7. Sandvig K, Skotland T, van Deurs B, Klokk TI (2013)
    Retrograde transport of protein toxins through the Golgi apparatus
    Histochem Cell Biol, 140 (3), 317-26
    DOI 10.1007/s00418-013-1111-z, PubMed 23765164
  8. Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
    Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
    Microbiology (Reading), 159 (Pt 11), 2283-2293
    DOI 10.1099/mic.0.069674-0, PubMed 24002748

Publications 2012

  1. Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T (2012)
    Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
    J Biol Chem, 287 (26), 21992-2003
    DOI 10.1074/jbc.M111.332643, PubMed 22539349
  2. Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
    Shiga toxins
    Toxicon, 60 (6), 1085-107
    DOI 10.1016/j.toxicon.2012.07.016, PubMed 22960449
  3. Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
    Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
    Biochim Biophys Acta, 1819 (11-12), 1154-63
    DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
  4. Ilina P, Hyvonen Z, Saura M, Sandvig K, Yliperttula M, Ruponen M (2012)
    Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
    J Control Release, 163 (3), 385-95
    DOI 10.1016/j.jconrel.2012.09.016, PubMed 23041276
  5. Iversen TG, Frerker N, Sandvig K (2012)
    Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
    J Nanobiotechnology, 10, 33
    DOI 10.1186/1477-3155-10-33, PubMed 22849338
  6. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK et al. (2012)
    Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
    PLoS Biol, 10 (12), e1001450
    DOI 10.1371/journal.pbio.1001450, PubMed 23271954
  7. Østerud B, Skotland T (2012)
    Doping analyses are not on safe ground
    Tidsskr Nor Laegeforen, 132 (8), 929-30
    DOI 10.4045/tidsskr.12.0252, PubMed 22562317
  8. Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
    Flotillins as regulators of ErbB2 levels in breast cancer
    Oncogene, 32 (29), 3443-51
    DOI 10.1038/onc.2012.357, PubMed 22869152
  9. Sandvig K, Llorente A (2012)
    Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
    Mol Cell Proteomics, 11 (7), M111.012914
    DOI 10.1074/mcp.M111.012914, PubMed 22457534
  10. Stratford EW, Castro R, Daffinrud J, Skårn M, Lauvrak S, Munthe E, Myklebost O (2012)
    Characterization of liposarcoma cell lines for preclinical and biological studies
    Sarcoma, 2012, 148614
    DOI 10.1155/2012/148614, PubMed 22911243
  11. Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
    Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
    PLoS One, 7 (7), e40429
    DOI 10.1371/journal.pone.0040429, PubMed 22792315

Publications 2011

  1. Cordara G, Egge-Jacobsen W, Johansen HT, Winter HC, Goldstein IJ, Sandvig K, Krengel U (2011)
    Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
    Biochem Biophys Res Commun, 408 (3), 405-10
    DOI 10.1016/j.bbrc.2011.04.031, PubMed 21513701
  2. Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H (2011)
    Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
    Traffic, 12 (10), 1417-31
    DOI 10.1111/j.1600-0854.2011.01243.x, PubMed 21722281
  3. Dyve Lingelem AB, Bergan J, Sandvig K (2011)
    Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
    Traffic, 13 (3), 443-54
    DOI 10.1111/j.1600-0854.2011.01319.x, PubMed 22132807
  4. Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
    Shiga toxin and its use in targeted cancer therapy and imaging
    Microb Biotechnol, 4 (1), 32-46
    DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370
  5. Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
    Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
    PLoS One, 6 (7), e21708
    DOI 10.1371/journal.pone.0021708, PubMed 21779335
  6. Iversen TG (2011)
    Nanoparticles hinder intracellular transport
    Trac-Trends Anal. Chem., 30 (10), VII-VIII
  7. Iversen TG, Skotland T, Sandvig K (2011)
    Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
    Nano Today, 6 (2), 176-185
  8. Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
    Role of phospholipase A(2) in retrograde transport of ricin
    Toxins (Basel), 3 (9), 1203-19
    DOI 10.3390/toxins3091203, PubMed 22069763
  9. Sandvig K, Pust S, Skotland T, van Deurs B (2011)
    Clathrin-independent endocytosis: mechanisms and function
    Curr Opin Cell Biol, 23 (4), 413-20
    DOI 10.1016/, PubMed 21466956
  10. Skotland T, Iversen TG, Sandvig K (2011)
    Comment on "short ligands affect modes of QD uptake and elimination in human cells"
    ACS Nano, 5 (10), 7690; author reply 7691-2
    DOI 10.1021/nn2021953, PubMed 22023400
  11. Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M (2011)
    A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
    Biochem J, 436 (2), 371-85
    DOI 10.1042/BJ20101493, PubMed 21388347
  12. Stratford EW, Castro R, Wennerstrom A, Holm R, Munthe E, Lauvrak S, Bjerkehagen B, Myklebost O (2011)
    Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
    Clin Sarcoma Res, 1 (1), 8
    DOI 10.1186/2045-3329-1-8, PubMed 22612877
  13. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
    Protein C mutation (A267T) results in ER retention and unfolded protein response activation
    PLoS One, 6 (8), e24009
    DOI 10.1371/journal.pone.0024009, PubMed 21901152

Publications 2010

  1. Landsverk OJ, Barois N, Gregers TF, Bakke O (2010)
    Invariant chain increases the half-life of MHC II by delaying endosomal maturation
    Immunol Cell Biol, 89 (5), 619-29
    DOI 10.1038/icb.2010.143, PubMed 21116285
  2. Pust S, Barth H, Sandvig K (2010)
    Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
    Cell Microbiol, 12 (12), 1809-20
    DOI 10.1111/j.1462-5822.2010.01512.x, PubMed 20690924
  3. Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
    Interplay between toxin transport and flotillin localization
    PLoS One, 5 (1), e8844
    DOI 10.1371/journal.pone.0008844, PubMed 20107503
  4. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
    Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    FEBS Lett, 584 (12), 2626-34
    DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
  5. Skotland T, Iversen TG, Sandvig K (2010)
    New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
    Nanomedicine, 6 (6), 730-7
    DOI 10.1016/j.nano.2010.05.002, PubMed 20570639
  6. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
    Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
    BMC Cell Biol, 11, 67
    DOI 10.1186/1471-2121-11-67, PubMed 20815936
  7. Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
    The Intracellular Journey of Shiga Toxins
    The Open Toxinology Journal, 3, 3-12
    PublikaID 24
  8. Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
    Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
    FEMS Immunol Med Microbiol, 61 (1), 63-75
    DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580
  9. Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K (2010)
    Shiga toxin increases formation of clathrin-coated pits through Syk kinase
    PLoS One, 5 (7), e10944
    DOI 10.1371/journal.pone.0010944, PubMed 20668539

Publications 2009

  1. Døving KB, Sandvig K, Kasumyan A (2009)
    Ligand-specific induction of endocytosis in taste receptor cells
    J Exp Biol, 212 (Pt 1), 42-9
    DOI 10.1242/jeb.025700, PubMed 19088209
  2. Dyve AB, Bergan J, Utskarpen A, Sandvig K (2009)
    Sorting nexin 8 regulates endosome-to-Golgi transport
    Biochem Biophys Res Commun, 390 (1), 109-14
    DOI 10.1016/j.bbrc.2009.09.076, PubMed 19782049
  3. Iversen TG, Frerker N, Sandvig K (2009)
    Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
    San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
    PublikaID 29
  4. Kaiser E, Pust S, Kroll C, Barth H (2009)
    Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
    Cell Microbiol, 11 (5), 780-95
    DOI 10.1111/j.1462-5822.2009.01291.x, PubMed 19159389
  5. Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K (2009)
    Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
    Traffic, 10 (7), 868-82
    DOI 10.1111/j.1600-0854.2009.00919.x, PubMed 19453975
  6. Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
    Endocytosis and retrograde transport of Shiga toxin
    Toxicon, 56 (7), 1181-5
    DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
  7. Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
    SNX4 in complex with clathrin and dynein: implications for endosome movement
    PLoS One, 4 (6), e5935
    DOI 10.1371/journal.pone.0005935, PubMed 19529763
  8. Skånland SS, Wälchli S, Sandvig K (2009)
    β-arrestins attenuate p38-mediated endosome to Golgi transport
    Cell Microbiol, 11 (5), 796-807
    DOI 10.1111/j.1462-5822.2009.01292.x, PubMed 19159388
  9. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168

Publications 2008

  1. Heine K, Pust S, Enzenmüller S, Barth H (2008)
    ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
    Infect Immun, 76 (10), 4600-8
    DOI 10.1128/IAI.00651-08, PubMed 18710868
  2. Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
    Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
    Histochem Cell Biol, 129 (3), 267-76
    DOI 10.1007/s00418-007-0376-5, PubMed 18193449
  3. Sandvig K, van Deurs B (2008)
    Cell biology: Viruses in camouflage
    Nature, 453 (7194), 466-7
    DOI 10.1038/453466a, PubMed 18497813
  4. Tekle C, Deurs Bv, Sandvig K, Iversen TG (2008)
    Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
    Nano Lett, 8 (7), 1858-65
    DOI 10.1021/nl0803848, PubMed 18570482

Publications 2007

  1. Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
    The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
    Exp Cell Res, 313 (8), 1696-709
    DOI 10.1016/j.yexcr.2007.02.017, PubMed 17382318
  2. Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
    Structural requirements for furin-induced cleavage and activation of Shiga toxin
    Biochem Biophys Res Commun, 357 (1), 144-9
    DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
  3. Llorente A, van Deurs B, Sandvig K (2007)
    Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
    Eur J Cell Biol, 86 (7), 405-15
    DOI 10.1016/j.ejcb.2007.05.001, PubMed 17601634
  4. Martín-Acebes MA, González-Magaldi M, Sandvig K, Sobrino F, Armas-Portela R (2007)
    Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
    Virology, 369 (1), 105-18
    DOI 10.1016/j.virol.2007.07.021, PubMed 17714753
  5. Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
    Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
    Traffic, 8 (3), 297-309
    DOI 10.1111/j.1600-0854.2006.00527.x, PubMed 17319803
  6. Spilsberg B, Llorente A, Sandvig K (2007)
    Polyunsaturated fatty acids regulate Shiga toxin transport
    Biochem Biophys Res Commun, 364 (2), 283-8
    DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073
  7. Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
    Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
    J Biol Chem, 282 (22), 16317-28
    DOI 10.1074/jbc.M610886200, PubMed 17403690
  8. Utskarpen A, Slagsvold HH, Dyve AB, Skånland SS, Sandvig K (2007)
    SNX1 and SNX2 mediate retrograde transport of Shiga toxin
    Biochem Biophys Res Commun, 358 (2), 566-70
    DOI 10.1016/j.bbrc.2007.04.159, PubMed 17498660

Publications 2006

  1. Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
    The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
    Mol Biol Cell, 17 (6), 2513-23
    DOI 10.1091/mbc.e05-10-0915, PubMed 16554368
  2. Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
    Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
    Traffic, 7 (9), 1243-53
    DOI 10.1111/j.1600-0854.2006.00456.x, PubMed 16919154
  3. Hollås H, Aukrust I, Grimmer S, Strand E, Flatmark T, Vedeler A (2006)
    Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
    Biochim Biophys Acta, 1763 (11), 1325-34
    DOI 10.1016/j.bbamcr.2006.08.043, PubMed 17045350
  4. Huynh T, Wälchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem Biophys Res Commun, 350 (4), 854-9
    DOI 10.1016/j.bbrc.2006.09.127, PubMed 17034763
  5. Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I (2006)
    A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
    Eur J Immunol, 36 (1), 129-38
    DOI 10.1002/eji.200535178, PubMed 16323243
  6. Slominska-Wojewodzka M, Gregers TF, Wälchli S, Sandvig K (2006)
    EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
    Mol Biol Cell, 17 (4), 1664-75
    DOI 10.1091/mbc.e05-10-0961, PubMed 16452630
  7. Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
    Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
    Traffic, 7 (6), 663-72
    DOI 10.1111/j.1600-0854.2006.00418.x, PubMed 16683916

Publications 2005

  1. Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
    Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
    Traffic, 6 (2), 144-56
    DOI 10.1111/j.1600-0854.2005.00258.x, PubMed 15634214
  2. Guerra L, Teter K, Lilley BN, Stenerlöw B, Holmes RK, Ploegh HL, Sandvig K, Thelestam M, Frisan T (2005)
    Cellular internalization of cytolethal distending toxin: a new end to a known pathway
    Cell Microbiol, 7 (7), 921-34
    DOI 10.1111/j.1462-5822.2005.00520.x, PubMed 15953025
  3. Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C (2005)
    The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
    J Neurosci, 25 (11), 2793-802
    DOI 10.1523/JNEUROSCI.4090-04.2005, PubMed 15772339
  4. Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
    Caveolae: stable membrane domains with a potential for internalization
    Traffic, 6 (9), 720-4
    DOI 10.1111/j.1600-0854.2005.00314.x, PubMed 16101676
  5. Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
    Shiga toxin regulates its entry in a Syk-dependent manner
    Mol Biol Cell, 17 (3), 1096-109
    DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
  6. Sandvig K, van Deurs B (2005)
    Delivery into cells: lessons learned from plant and bacterial toxins
    Gene Ther, 12 (11), 865-72
    DOI 10.1038/, PubMed 15815697
  7. Sioud M, Wälchli S (2005)
    Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
    Methods Mol Biol, 309, 83-91
    DOI 10.1385/1-59259-935-4:083, PubMed 15990399
  8. Spilsberg B, Hanada K, Sandvig K (2005)
    Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
    Biochem Biophys Res Commun, 329 (2), 465-73
    DOI 10.1016/j.bbrc.2005.02.005, PubMed 15737610
  9. Spilsberg B, Sandvig K, Wälchli S (2005)
    Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
    Toxicon, 46 (8), 900-6
    DOI 10.1016/j.toxicon.2005.08.015, PubMed 16260019
  10. Torgersen ML, Lauvrak SU, Sandvig K (2005)
    The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
    FEBS J, 272 (16), 4103-13
    DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193

Publications 2004

  1. Engelhardt M, Pfadenhauer K, Zentner J, Grimmer S, Wachenfeld-Wahl C, Heidenreich P, Loeprecht H, Wölfle KD (2004)
    [Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
    Zentralbl Chir, 129 (3), 178-82
    DOI 10.1055/s-2004-822798, PubMed 15237321
  2. Jacobs CM, Boldingh KA, Slagsvold HH, Thoresen GH, Paulsen RE (2004)
    ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
    J Biol Chem, 279 (48), 50097-101
    DOI 10.1074/jbc.M409145200, PubMed 15448159
  3. Lauvrak SU, Torgersen ML, Sandvig K (2004)
    Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
    J Cell Sci, 117 (Pt 11), 2321-31
    DOI 10.1242/jcs.01081, PubMed 15126632
  4. Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
    Pathways followed by protein toxins into cells
    Int J Med Microbiol, 293 (7-8), 483-90
    DOI 10.1078/1438-4221-00294, PubMed 15149022

Publications 2003

  1. Bråthe A, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2003)
    Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
    Bioorg Med Chem Lett, 13 (5), 877-80
    DOI 10.1016/s0960-894x(03)00011-8, PubMed 12617912
  2. Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
    Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
    Proc Natl Acad Sci U S A, 100 (9), 5175-80
    DOI 10.1073/pnas.0534231100, PubMed 12682302
  3. Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
    Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
    J Biol Chem, 278 (37), 35850-5
    DOI 10.1074/jbc.M303425200, PubMed 12847103
  4. Sandvig K, van Deurs B (2003)
    Cholera toxin internalization and intoxication - Reply
    J. Cell Sci., 116 (3), 432-433
  5. Spilsberg B, Van Meer G, Sandvig K (2003)
    Role of lipids in the retrograde pathway of ricin intoxication
    Traffic, 4 (8), 544-52
    DOI 10.1034/j.1600-0854.2003.00111.x, PubMed 12839497
  6. van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
    Caveolae: anchored, multifunctional platforms in the lipid ocean
    Trends Cell Biol, 13 (2), 92-100
    DOI 10.1016/s0962-8924(02)00039-9, PubMed 12559760
  7. Ying M, Grimmer S, Iversen TG, Van Deurs B, Sandvig K (2003)
    Cholesterol loading induces a block in the exit of VSVG from the TGN
    Traffic, 4 (11), 772-84
    DOI 10.1034/j.1600-0854.2003.00134.x, PubMed 14617359

Publications 2002

  1. Andresen G, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2002)
    Cytotoxic and antibacterial activity of 2-oxopurine derivatives
    Bioorg Med Chem Lett, 12 (4), 567-9
    DOI 10.1016/s0960-894x(01)00803-4, PubMed 11844673
  2. Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
    Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
    J Biol Chem, 278 (3), 1991-7
    DOI 10.1074/jbc.M209982200, PubMed 12419802
  3. Grimmer S, van Deurs B, Sandvig K (2002)
    Membrane ruffling and macropinocytosis in A431 cells require cholesterol
    J Cell Sci, 115 (Pt 14), 2953-62
    PubMed 12082155
  4. Gundersen LL, Nissen-Meyer J, Spilsberg B (2002)
    Synthesis and antimycobacterial activity of 6-arylpurines: the requirements for the N-9 substituent in active antimycobacterial purines
    J Med Chem, 45 (6), 1383-6
    DOI 10.1021/jm0110284, PubMed 11882008
  5. Lagaudrière-Gesbert C, Newmyer SL, Gregers TF, Bakke O, Ploegh HL (2002)
    Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments
    Proc Natl Acad Sci U S A, 99 (3), 1515-20
    DOI 10.1073/pnas.042688099, PubMed 11818572
  6. Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
    Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
    J Cell Sci, 115 (Pt 17), 3449-56
    PubMed 12154075
  7. Nordeng TW, Gregers TF, Kongsvik TL, Méresse S, Gorvel JP, Jourdan F, Motta A, Bakke O (2002)
    The cytoplasmic tail of invariant chain regulates endosome fusion and morphology
    Mol Biol Cell, 13 (6), 1846-56
    DOI 10.1091/mbc.01-10-0478, PubMed 12058053
  8. Roepstorff K, Thomsen P, Sandvig K, van Deurs B (2002)
    Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
    J Biol Chem, 277 (21), 18954-60
    DOI 10.1074/jbc.M201422200, PubMed 11886870
  9. Sandvig K, van Deurs B (2002)
    Membrane traffic exploited by protein toxins
    Annu Rev Cell Dev Biol, 18, 1-24
    DOI 10.1146/annurev.cellbio.18.011502.142107, PubMed 12142266
  10. Sandvig K, van Deurs B (2002)
    Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
    FEBS Lett, 529 (1), 49-53
    DOI 10.1016/s0014-5793(02)03182-4, PubMed 12354612
  11. Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S (2002)
    Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
    J Biol Chem, 278 (5), 3331-8
    DOI 10.1074/jbc.M207966200, PubMed 12424246

Publications 2001

  1. Garred Ø, Rodal SK, van Deurs B, Sandvig K (2001)
    Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
    Traffic, 2 (1), 26-36
    DOI 10.1034/j.1600-0854.2001.020105.x, PubMed 11208166
  2. Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
    Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
    Mol Biol Cell, 12 (7), 2099-107
    DOI 10.1091/mbc.12.7.2099, PubMed 11452006
  3. Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
    Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
    J Cell Sci, 114 (Pt 2), 335-43
    PubMed 11148135
  4. Lunde E, Rasmussen IB, Eidem JK, Gregers TF, Western KH, Bogen B, Sandlie I (2001)
    'Troy-bodies': antibodies as vector proteins for T cell epitopes
    Biomol Eng, 18 (3), 109-16
    DOI 10.1016/s1389-0344(01)00091-0, PubMed 11566602
  5. Sandvig K (2001)
    Shiga toxins
    Toxicon, 39 (11), 1629-35
    DOI 10.1016/s0041-0101(01)00150-7, PubMed 11595626
  6. Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
    Pathways followed by ricin and Shiga toxin into cells
    Histochem Cell Biol, 117 (2), 131-41
    DOI 10.1007/s00418-001-0346-2, PubMed 11935289
  7. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
    In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
    Int J Cancer, 92 (5), 761-6
    DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>;2-4, PubMed 11340584
  8. Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
    Internalization of cholera toxin by different endocytic mechanisms
    J Cell Sci, 114 (Pt 20), 3737-47
    PubMed 11707525

Publications 2000

  1. Dahl C, Haug LS, Spilsberg B, Johansen J, Ostvold AC, Diemer NH (2000)
    Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
    Neurochem Int, 36 (4-5), 379-88
    DOI 10.1016/s0197-0186(99)00129-1, PubMed 10733005
  2. Eidem JK, Rasmussen IB, Lunde E, Gregers TF, Rees AR, Bogen B, Sandlie I (2000)
    Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
    J Immunol Methods, 245 (1-2), 119-31
    DOI 10.1016/s0022-1759(00)00274-x, PubMed 11042289
  3. Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
    Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
    J Biol Chem, 275 (6), 4363-8
    DOI 10.1074/jbc.275.6.4363, PubMed 10660606
  4. Falnes PO, Sandvig K (2000)
    Penetration of protein toxins into cells
    Curr Opin Cell Biol, 12 (4), 407-13
    DOI 10.1016/s0955-0674(00)00109-5, PubMed 10873820
  5. Grimmer S, Iversen TG, van Deurs B, Sandvig K (2000)
    Endosome to Golgi transport of ricin is regulated by cholesterol
    Mol Biol Cell, 11 (12), 4205-16
    DOI 10.1091/mbc.11.12.4205, PubMed 11102518
  6. Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
    Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
    J Cell Sci, 113 ( Pt 7), 1213-21
    PubMed 10704372
  7. Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
    Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
    Mol Biol Cell, 11 (2), 481-95
    DOI 10.1091/mbc.11.2.481, PubMed 10679008
  8. Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
    Ricin transport into cells: studies of endocytosis and intracellular transport
    Int J Med Microbiol, 290 (4-5), 415-20
    DOI 10.1016/S1438-4221(00)80055-7, PubMed 11111920
  9. Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
    Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
    Eur J Cell Biol, 79 (7), 447-57
    DOI 10.1078/0171-9335-00071, PubMed 10961444
  10. Sandvig K, van Deurs B (2000)
    Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
    EMBO J, 19 (22), 5943-50
    DOI 10.1093/emboj/19.22.5943, PubMed 11080141
  11. Selbo PK, Sandvig K, Kirveliene V, Berg K (2000)
    Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
    Biochim Biophys Acta, 1475 (3), 307-13
    DOI 10.1016/s0304-4165(00)00082-9, PubMed 10913830
  12. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
    Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
    Int J Cancer, 87 (6), 853-9
    DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>;2-0, PubMed 10956397
  13. Stahlhut M, Sandvig K, van Deurs B (2000)
    Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
    Exp Cell Res, 261 (1), 111-8
    DOI 10.1006/excr.2000.4960, PubMed 11082281

Publications 1999

  1. Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
    Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
    Cancer Res, 59 (6), 1180-3
    PubMed 10096543
  2. Hjertner O, Torgersen ML, Seidel C, Hjorth-Hansen H, Waage A, Børset M, Sundan A (1999)
    Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
    Blood, 94 (11), 3883-8
    PubMed 10572104
  3. Rodal SK, Skretting G, Garred O, Vilhardt F, van Deurs B, Sandvig K (1999)
    Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
    Mol Biol Cell, 10 (4), 961-74
    DOI 10.1091/mbc.10.4.961, PubMed 10198050
  4. Sandvig K, van Deurs B (1999)
    Endocytosis and intracellular transport of ricin: recent discoveries
    FEBS Lett, 452 (1-2), 67-70
    DOI 10.1016/s0014-5793(99)00529-3, PubMed 10376680
  5. Skretting G, Torgersen ML, van Deurs B, Sandvig K (1999)
    Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
    J Cell Sci, 112 ( Pt 22), 3899-909
    PubMed 10547351
  6. Vilhardt F, Nielsen M, Sandvig K, van Deurs B (1999)
    Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
    Mol Biol Cell, 10 (1), 179-95
    DOI 10.1091/mbc.10.1.179, PubMed 9880335

Publications 1998

  1. Drolsum L, Haaskjold E, Sandvig K (1998)
    Phacoemulsification in eyes with pseudoexfoliation
    J Cataract Refract Surg, 24 (6), 787-92
    DOI 10.1016/s0886-3350(98)80132-6, PubMed 9642589
  2. Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
    Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
    J Cell Biol, 140 (3), 553-63
    DOI 10.1083/jcb.140.3.553, PubMed 9456316
  3. Llorente A, van Deurs B, Sandvig K (1998)
    Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
    FEBS Lett, 431 (2), 200-4
    DOI 10.1016/s0014-5793(98)00754-6, PubMed 9708902
  4. Vogel U, Sandvig K, van Deurs B (1998)
    Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
    J Cell Sci, 111 ( Pt 6), 825-32
    PubMed 9472010

Publications 1997

  1. Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
    Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
    J Biol Chem, 272 (17), 11414-9
    DOI 10.1074/jbc.272.17.11414, PubMed 9111051
  2. Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
    [Self-inhibiting N-glycosidase activity of shigella toxin]
    Mol Biol (Mosk), 31 (3), 528-35
    PubMed 9297098
  3. Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
    Self-inhibition of N-glycosidase activity of shiga toxin
    Mol. Biol., 31 (3), 441-447
  4. Sandvig K, Garred O, van Deurs B (1997)
    Intracellular transport and processing of protein toxins produced by enteric bacteria
    Adv Exp Med Biol, 412, 225-32
    DOI 10.1007/978-1-4899-1828-4_34, PubMed 9192018

Publications 1996

  1. Allen ED, Burton RL, Webber SK, Haaskjold E, Sandvig K, Jyrkkiö H, Leite E, Nyström A, Wollensak J (1996)
    Comparison of a diffractive bifocal and a monofocal intraocular lens
    J Cataract Refract Surg, 22 (4), 446-51
    DOI 10.1016/s0886-3350(96)80040-x, PubMed 8733848
  2. Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
    Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
    Exp Cell Res, 227 (2), 298-308
    DOI 10.1006/excr.1996.0279, PubMed 8831568
  3. Sandvig K, Garred O, van Deurs B (1996)
    Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
    Proc Natl Acad Sci U S A, 93 (22), 12339-43
    DOI 10.1073/pnas.93.22.12339, PubMed 8901582
  4. Sandvig K, Garred O, van Helvoort A, van Meer G, van Deurs B (1996)
    Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
    Mol Biol Cell, 7 (9), 1391-404
    DOI 10.1091/mbc.7.9.1391, PubMed 8885234
  5. Sandvig K, van Deurs B (1996)
    Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
    Physiol Rev, 76 (4), 949-66
    DOI 10.1152/physrev.1996.76.4.949, PubMed 8874490
  6. van Deurs B, Holm PK, Sandvig K (1996)
    Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
    Eur J Cell Biol, 69 (4), 343-50
    PubMed 8741216
  7. van Deurs B, von Bũlow F, Vilhardt F, Holm PK, Sandvig K (1996)
    Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
    J Cell Sci, 109 ( Pt 7), 1655-65
    PubMed 8832388

Publications 1995

    Trends Microbiol., 3 (5), 167-168
  2. Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
    Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
    Exp Cell Res, 218 (1), 39-49
    DOI 10.1006/excr.1995.1128, PubMed 7737376
  3. Garred O, van Deurs B, Sandvig K (1995)
    Furin-induced cleavage and activation of Shiga toxin
    J Biol Chem, 270 (18), 10817-21
    DOI 10.1074/jbc.270.18.10817, PubMed 7738018
  4. Holm PK, Eker P, Sandvig K, van Deurs B (1995)
    Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
    Exp Cell Res, 217 (1), 157-68
    DOI 10.1006/excr.1995.1075, PubMed 7867714
  5. Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
    Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
    Biochem J, 310 ( Pt 1), 285-9
    DOI 10.1042/bj3100285, PubMed 7646457
  6. van Deurs B, Holm PK, Kayser L, Sandvig K (1995)
    Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
    Eur J Cell Biol, 66 (4), 309-23
    PubMed 7544728

Publications 1994

  1. Eker P, Holm PK, van Deurs B, Sandvig K (1994)
    Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
    J Biol Chem, 269 (28), 18607-15
    PubMed 8034609
  2. Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
    Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
    EMBO J, 13 (19), 4433-9
    DOI 10.1002/j.1460-2075.1994.tb06765.x, PubMed 7523112
  3. Madshus IH, Wiedlocha A, Sandvig K (1994)
    Intermediates in translocation of diphtheria toxin across the plasma membrane
    J Biol Chem, 269 (6), 4648-52
    PubMed 7508447
    INT CONGR SER, 1072, 139-146
  5. Sandvig K, Ryd M, Garred O, Schweda E, Holm PK, van Deurs B (1994)
    Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
    J Cell Biol, 126 (1), 53-64
    DOI 10.1083/jcb.126.1.53, PubMed 8027186
  6. Sandvig K, van Deurs B (1994)
    Endocytosis without clathrin
    Trends Cell Biol, 4 (8), 275-7
    DOI 10.1016/0962-8924(94)90211-9, PubMed 14731589
  7. Sandvig K, van Deurs B (1994)
    Endocytosis and intracellular sorting of ricin and Shiga toxin
    FEBS Lett, 346 (1), 99-102
    DOI 10.1016/0014-5793(94)00281-9, PubMed 8206167
    ZBL BAKT S, 24, 365-374
  9. Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
    Dual mode of signal transduction by externally added acidic fibroblast growth factor
    Cell, 76 (6), 1039-51
    DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061

Publications 1993

  1. Hansen SH, Sandvig K, van Deurs B (1993)
    Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
    J Cell Biol, 123 (1), 89-97
    DOI 10.1083/jcb.123.1.89, PubMed 8408209
  2. Hansen SH, Sandvig K, van Deurs B (1993)
    Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
    J Cell Biol, 121 (1), 61-72
    DOI 10.1083/jcb.121.1.61, PubMed 8458873
  3. Holm PK, Hansen SH, Sandvig K, van Deurs B (1993)
    Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
    Eur J Cell Biol, 62 (2), 362-71
    PubMed 7925492
  4. Ludt J, Sandvig K, Olsnes S (1993)
    Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
    J Membr Biol, 134 (2), 143-53
    DOI 10.1007/BF00232750, PubMed 8411117
  5. Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
    Entry of protein toxins in polarized epithelial cells
    Cancer Res, 53 (8), 1755-60
    PubMed 8467493
  6. Olsnes S, van Deurs B, Sandvig K (1993)
    Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
    Med Microbiol Immunol, 182 (2), 51-61
    DOI 10.1007/BF00189373, PubMed 8392658
  7. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, Van Deurs B (1993)
    Entry of Shiga toxin into cells
    Zentralbl Bakteriol, 278 (2-3), 296-305
    DOI 10.1016/s0934-8840(11)80846-7, PubMed 8347933
  8. Sandvig K, Garred O, Holm PK, van Deurs B (1993)
    Endocytosis and intracellular transport of protein toxins
    Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
    DOI 10.1042/bst0210707, PubMed 8224494
  9. van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993)
    Multivesicular bodies in HEp-2 cells are maturing endosomes
    Eur J Cell Biol, 61 (2), 208-24
    PubMed 8223712
  10. van Deurs B, Holm PK, Sandvig K, Hansen SH (1993)
    Are caveolae involved in clathrin-independent endocytosis?
    Trends Cell Biol, 3 (8), 249-51
    DOI 10.1016/0962-8924(93)90045-3, PubMed 14731741

Publications 1992

  1. Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
    Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
    J Biol Chem, 267 (17), 12284-90
    PubMed 1376320
  2. Hansen SH, Sandvig K, van Deurs B (1992)
    Internalization efficiency of the transferrin receptor
    Exp Cell Res, 199 (1), 19-28
    DOI 10.1016/0014-4827(92)90457-j, PubMed 1735458
  3. O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
    Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
    Curr Top Microbiol Immunol, 180, 65-94
    DOI 10.1007/978-3-642-77238-2_4, PubMed 1324134
  4. Prydz K, Hansen SH, Sandvig K, van Deurs B (1992)
    Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
    J Cell Biol, 119 (2), 259-72
    DOI 10.1083/jcb.119.2.259, PubMed 1400572
  5. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Protein toxins: mode of action and cell entry
    Biochem Soc Trans, 20 (4), 724-7
    DOI 10.1042/bst0200724, PubMed 1487049
  6. Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
    Nature, 358 (6386), 510-2
    DOI 10.1038/358510a0, PubMed 1641040
  7. Sandvig K, van Deurs B (1992)
    Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
    Exp Cell Res, 200 (2), 253-62
    DOI 10.1016/0014-4827(92)90171-4, PubMed 1572394

Publications 1991

  1. Hansen SH, Sandvig K, van Deurs B (1991)
    The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
    J Cell Biol, 113 (4), 731-41
    DOI 10.1083/jcb.113.4.731, PubMed 1673969
  2. Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
    Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
    J Membr Biol, 119 (2), 179-86
    DOI 10.1007/BF01871417, PubMed 2046087
  3. Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
    Entry of diphtheria toxin-protein A chimeras into cells
    J Biol Chem, 266 (26), 17446-53
    PubMed 1894632
  4. Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
    Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
    J Cell Biochem, 47 (3), 251-60
    DOI 10.1002/jcb.240470311, PubMed 1791187
  5. Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
    Bacterial protein toxins acting on intracellular targets
    Semin Cell Biol, 2 (1), 7-14
    PubMed 1954345
  6. Sandvig K, Prydz K, Hansen SH, van Deurs B (1991)
    Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
    J Cell Biol, 115 (4), 971-81
    DOI 10.1083/jcb.115.4.971, PubMed 1955466
  7. Sandvig K, Prydz K, Ryd M, van Deurs B (1991)
    Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
    J Cell Biol, 113 (3), 553-62
    DOI 10.1083/jcb.113.3.553, PubMed 1901867
  8. Sandvig K, van Deurs B (1991)
    Endocytosis without clathrin (a minireview)
    Cell Biol Int Rep, 15 (1), 3-8
    DOI 10.1016/0309-1651(91)90077-v, PubMed 1900741
  9. Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
    Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
    J Cell Biol, 113 (5), 1025-32
    DOI 10.1083/jcb.113.5.1025, PubMed 2040642
  10. Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
    Internalization and action of an immunotoxin containing mistletoe lectin A-chain
    Cancer Res, 51 (3), 916-20
    PubMed 1988131

Publications 1990

  1. Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
    Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
    J Physiol (Paris), 84 (3), 191-6
    PubMed 1705980
  2. Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
    Protein toxins with intracellular targets
    Microb Pathog, 8 (3), 163-8
    DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341
  3. Sandvig K, van Deurs B (1990)
    Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
    J Biol Chem, 265 (11), 6382-8
    PubMed 1969411
  4. Tønnessen TI, Sandvig K, Olsnes S (1990)
    Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
    Am J Physiol, 258 (6 Pt 1), C1117-26
    DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200
  5. van Deurs B, Hansen SH, Petersen OW, Melby EL, Sandvig K (1990)
    Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
    Eur J Cell Biol, 51 (1), 96-109
    PubMed 2328741

Publications 1989

  1. Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
    Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
    Exp Cell Res, 185 (2), 373-86
    DOI 10.1016/0014-4827(89)90307-8, PubMed 2689197
  2. McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
    Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
    EMBO J, 8 (10), 2843-8
    DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631
  3. Moskaug JO, Sandvig K, Olsnes S (1989)
    Role of anions in low pH-induced translocation of diphtheria toxin
    J Biol Chem, 264 (19), 11367-72
    PubMed 2500440
  4. Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
    Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
    J Biol Chem, 264 (26), 15709-13
    PubMed 2768283
  5. Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
    Immunotoxins--entry into cells and mechanisms of action
    Immunol Today, 10 (9), 291-5
    PubMed 2686677
    J. Biol. Chem., 264 (22), 12749-12751
  7. Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
    Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
    J Biol Chem, 264 (22), 12747-51
    PubMed 2753882
  8. Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
    Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
    J Cell Biol, 108 (4), 1331-43
    DOI 10.1083/jcb.108.4.1331, PubMed 2564398
  9. Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
    Control of coated-pit function by cytoplasmic pH
    Methods Cell Biol, 32, 365-82
    DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206
  10. Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
    Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
    EMBO J, 8 (10), 2849-53
    DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538
  11. Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
    Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
    Biochem Pharmacol, 38 (20), 3583-91
    DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647
  12. Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
    Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
    J Pharmacol Exp Ther, 248 (3), 1197-206
    PubMed 2703970
  13. van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
    The ways of endocytosis
    Int Rev Cytol, 117, 131-77
    DOI 10.1016/s0074-7696(08)61336-4, PubMed 2573583
  14. van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
    [Endocytosis, intracellular transport and sorting of proteins]
    Nord Med, 104 (1), 9-11
    PubMed 2911460

Publications 1988

  1. Holtskog R, Sandvig K, Olsnes S (1988)
    Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
    Oncology, 45 (3), 172-9
    DOI 10.1159/000226557, PubMed 3368193
  2. Moskaug JO, Sandvig K, Olsnes S (1988)
    Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
    J Biol Chem, 263 (5), 2518-25
    PubMed 3339019
  3. Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
    Diphtheria toxin entry: protein translocation in the reverse direction
    Trends Biochem Sci, 13 (9), 348-51
    DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713
  4. Olsnes S, Sandvig K (1988)
    How protein toxins enter and kill cells
    Cancer Treat Res, 37, 39-73
    DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634
  5. Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
    Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
    J Biol Chem, 263 (23), 11117-25
    PubMed 3403517
  6. Sandvig K, Olsnes S (1988)
    Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
    J Biol Chem, 263 (25), 12352-9
    PubMed 2457582
  7. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
    Inhibition of endocytosis from coated pits by acidification of the cytosol
    J Cell Biochem, 36 (1), 73-81
    DOI 10.1002/jcb.240360108, PubMed 2893802
  8. Stenmark H, Olsnes S, Sandvig K (1988)
    Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
    J Biol Chem, 263 (26), 13449-55
    PubMed 3417666
  9. van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
    Estimation of the amount of internalized ricin that reaches the trans-Golgi network
    J Cell Biol, 106 (2), 253-67
    DOI 10.1083/jcb.106.2.253, PubMed 2892843

Publications 1987

  1. Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
    Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
    Exp Cell Res, 170 (2), 483-90
    DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553
  2. Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
    Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
    J Cell Physiol, 131 (1), 14-22
    DOI 10.1002/jcp.1041310104, PubMed 3032992
  3. Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
    Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
    J Cell Physiol, 131 (1), 6-13
    DOI 10.1002/jcp.1041310103, PubMed 3571337
  4. Moskaug JO, Sandvig K, Olsnes S (1987)
    Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
    J Biol Chem, 262 (21), 10339-45
    PubMed 3112141
  5. Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
    Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
    J Cell Physiol, 132 (2), 192-202
    DOI 10.1002/jcp.1041320203, PubMed 3624315
  6. Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
    Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
    Biochemistry, 26 (10), 2778-85
    DOI 10.1021/bi00384a019, PubMed 3606992
  7. Sandvig K, Brown JE (1987)
    Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
    Infect Immun, 55 (2), 298-303
    DOI 10.1128/IAI.55.2.298-303.1987, PubMed 3542829
  8. Sandvig K, Moskaug JO (1987)
    Pseudomonas toxin binds triton X-114 at low pH
    Biochem J, 245 (3), 899-901
    DOI 10.1042/bj2450899, PubMed 3117052
  9. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
    Acidification of the cytosol inhibits endocytosis from coated pits
    J Cell Biol, 105 (2), 679-89
    DOI 10.1083/jcb.105.2.679, PubMed 2887575
  10. Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
    Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
    J Cell Physiol, 132 (2), 183-91
    DOI 10.1002/jcp.1041320202, PubMed 3624314
  11. van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
    Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
    Exp Cell Res, 171 (1), 137-52
    DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628

Publications 1986

  1. Olsnes S, Carvajal E, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
    J Biol Chem, 261 (4), 1562-9
    PubMed 3632976
  2. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
    J Biol Chem, 261 (4), 1542-52
    PubMed 3944100
  3. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
    J Biol Chem, 261 (4), 1553-61
    PubMed 3944101
  4. Olsnes S, Tønnessen TI, Sandvig K (1986)
    pH-regulated anion antiport in nucleated mammalian cells
    J Cell Biol, 102 (3), 967-71
    DOI 10.1083/jcb.102.3.967, PubMed 3949885
  5. Sandvig K, Olsnes S (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
    J Biol Chem, 261 (4), 1570-5
    PubMed 2418015
  6. Sandvig K, Tønnessen TI, Olsnes S (1986)
    Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
    Cancer Res, 46 (12 Pt 1), 6418-22
    PubMed 3096563
    J. Biol. Chem., 261 (25), 1639-1644
  8. Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
    Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
    J Biol Chem, 261 (25), 11639-44
    PubMed 3745160
  9. van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
    Routing of internalized ricin and ricin conjugates to the Golgi complex
    J Cell Biol, 102 (1), 37-47
    DOI 10.1083/jcb.102.1.37, PubMed 3001103

Publications 1985

  1. Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
    Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
    J Cell Physiol, 122 (2), 193-9
    DOI 10.1002/jcp.1041220205, PubMed 3844014
  2. Madshus IH, Sandvig K, Olsnes S (1985)
    Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
    Exp Cell Res, 160 (1), 240-4
    DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095
  3. Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
    Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
    Biochim Biophys Acta, 846 (3), 334-41
    DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483
  4. Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
    Entry mechanisms of protein toxins and picornaviruses
    Biochem Soc Symp, 50, 171-91
    PubMed 3915869
    Biochem. Soc. Symp. (50), 171-191
  6. Sandvig K, Olsnes S (1985)
    Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
    Biochem J, 228 (2), 521-3
    DOI 10.1042/bj2280521, PubMed 2990449
  7. Sandvig K, Sundan A, Olsnes S (1985)
    Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
    J Cell Physiol, 124 (1), 54-60
    DOI 10.1002/jcp.1041240110, PubMed 3930519
  8. Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
    Properties of volkensin, a toxic lectin from Adenia volkensii
    J Biol Chem, 260 (27), 14589-95
    PubMed 3932357
    J. Biol. Chem., 260 (27), 4589-4595
  10. van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
    Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
    Exp Cell Res, 159 (2), 287-304
    DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159

Publications 1984

  1. Madshus IH, Olsnes S, Sandvig K (1984)
    Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
    J Cell Biol, 98 (4), 1194-200
    DOI 10.1083/jcb.98.4.1194, PubMed 6325467
  2. Madshus IH, Olsnes S, Sandvig K (1984)
    Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
    Virology, 139 (2), 346-57
    DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029
  3. Madshus IH, Olsnes S, Sandvig K (1984)
    Requirements for entry of poliovirus RNA into cells at low pH
    EMBO J, 3 (9), 1945-50
    DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049
  4. Sandvig K, Madshus IH, Olsnes S (1984)
    Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
    Biochem J, 219 (3), 935-40
    DOI 10.1042/bj2190935, PubMed 6331401
  5. Sandvig K, Olsnes S (1984)
    Receptor-mediated entry of protein toxins into cells
    Acta Histochem Suppl, 29, 79-94
    PubMed 6144140
  6. Sandvig K, Olsnes S (1984)
    Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
    J Cell Physiol, 119 (1), 7-14
    DOI 10.1002/jcp.1041190103, PubMed 6707104
  7. Sandvig K, Sundan A, Olsnes S (1984)
    Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
    J Cell Biol, 98 (3), 963-70
    DOI 10.1083/jcb.98.3.963, PubMed 6699094
  8. Sundan A, Sandvig K, Olsnes S (1984)
    Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
    Cancer Res, 44 (11), 4919-23
    PubMed 6435858
  9. Sundan A, Sandvig K, Olsnes S (1984)
    Calmodulin antagonists sensitize cells to pseudomonas toxin
    J Cell Physiol, 119 (1), 15-22
    DOI 10.1002/jcp.1041190104, PubMed 6707099

Publications 1983

  1. Sundan A, Sandvig K, Olsnes S (1983)
    Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
    Biochem Biophys Res Commun, 117 (2), 562-7
    DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
  2. Sundan A, Sandvig K, Olsnes S (1983)
    Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
    Biochim Biophys Acta, 761 (3), 296-302
    DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Publications 1982

  1. Olsnes S, Haylett T, Sandvig K (1982)
    The toxic lectin modeccin
    Methods Enzymol, 83, 357-62
    DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935
  2. Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
    Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
    J Biol Chem, 257 (22), 13263-70
    PubMed 7142144
  3. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
    J Biol Chem, 257 (13), 7495-503
    PubMed 6806276
  4. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
    J Biol Chem, 257 (13), 7504-13
    PubMed 7085634
  5. Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
    Action of viscumin, a toxic lectin from mistletoe, on cells in culture
    J Biol Chem, 257 (22), 13271-7
    PubMed 7142145
  6. Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
    Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
    J Biol Chem, 257 (16), 9733-9
    PubMed 7107588

Publications 1981

  1. Sandvig K, Olsnes S (1981)
    Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
    J Biol Chem, 256 (17), 9068-76
    PubMed 7263699
  2. Sandvig K, Olsnes S (1981)
    Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
    Biochem J, 194 (3), 821-7
    DOI 10.1042/bj1940821, PubMed 7306026

Publications 1980

  1. Sandvig K (1980)
    [Intracellular mediators for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (15), 1021-23
    PubMed 6250248
  2. Sandvig K (1980)
    [Receptors for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
    PubMed 6250247
  3. Sandvig K, Olsnes S (1980)
    Diphtheria toxin entry into cells is facilitated by low pH
    J Cell Biol, 87 (3 Pt 1), 828-32
    DOI 10.1083/jcb.87.3.828, PubMed 7462324

Publications 1979

  1. Sandvig K, Olsnes S (1979)
    Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
    Exp Cell Res, 121 (1), 15-25
    DOI 10.1016/0014-4827(79)90439-7, PubMed 446525
  2. Sandvig K, Olsnes S, Pihl A (1979)
    Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
    Biochem Biophys Res Commun, 90 (2), 648-55
    DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Publications 1978

  1. Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
    Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
    J Supramol Struct, 9 (1), 15-25
    DOI 10.1002/jss.400090103, PubMed 732310
  2. Sandvig K (1978)
    Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
    FEBS Lett, 89 (2), 233-6
    DOI 10.1016/0014-5793(78)80225-7, PubMed 658411
  3. Sandvig K, Olsnes S, Pihl A (1978)
    Chemical modifications of the toxic lectins abrin and ricin
    Eur J Biochem, 84 (2), 323-31
    DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792
  4. Sandvig K, Olsnes S, Pihl A (1978)
    Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
    Eur J Biochem, 82 (1), 13-23
    DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666
  5. Sandvig K, Olsnes S, Pihl A (1978)
    Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
    Eur J Biochem, 88 (1), 307-13
    DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847

Publications 1977

  1. Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
    Modeccin--a plant toxin inhibiting protein synthesis
    Biochem Biophys Res Commun, 79 (4), 1176-83
    DOI 10.1016/0006-291x(77)91130-5, PubMed 603653

Publications 1976

  1. Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
    Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
    J Biol Chem, 251 (13), 3985-92
    PubMed 932017
  2. Sandvig K, Olsnes S, Pihl A (1976)
    Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
    J Biol Chem, 251 (13), 3977-84
    PubMed 6468
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