Adam Brian Robertson

  • Group Leader; PhD
  • +47 23 07 40 65
Oslo University Hospital

Department of Molecular Microbiology

Building B, 3rd floor, Room B2.3069

Sognsvannsveien 20

Publications 2019

Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131

Publications 2016

Klungland A, Robertson AB (2016)
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Free Radic Biol Med, 107, 62-68
DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639

Vander Zanden CM, Rowe RK, Broad AJ, Robertson AB, Ho PS (2016)
Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions
Biochemistry, 55 (41), 5781-5789
DOI 10.1021/acs.biochem.6b00801, PubMed 27653243

Weber AR, Krawczyk C, Robertson AB, Kuśnierczyk A, Vågbø CB, Schuermann D, Klungland A, Schär P (2016)
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
Nat Commun, 7, 10806
DOI 10.1038/ncomms10806, PubMed 26932196

Publications 2014

Robertson AB, Dahl JA, Klungland A (2014)
DNA metabolism: bases of DNA repair and regulation
Nat Chem Biol, 10 (7), 487-8
DOI 10.1038/nchembio.1553, PubMed 24937064

Robertson AB, Robertson J, Fusser M, Klungland A (2014)
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Nucleic Acids Res, 42 (21), 13280-93
DOI 10.1093/nar/gku1032, PubMed 25355512

Publications 2013

Solberg A, Robertson AB, Aronsen JM, Rognmo Ø, Sjaastad I, Wisløff U, Klungland A (2013)
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141

Publications 2012

Robertson AB, Dahl JA, Ougland R, Klungland A (2012)
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads
Nat Protoc, 7 (2), 340-50
DOI 10.1038/nprot.2011.443, PubMed 22281869

Robertson AB, Matson SW (2012)
Reconstitution of the very short patch repair pathway from Escherichia coli
J Biol Chem, 287 (39), 32953-66
DOI 10.1074/jbc.M112.384321, PubMed 22846989

Publications 2011

Robertson AB, Dahl JA, Vågbø CB, Tripathi P, Krokan HE, Klungland A (2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Res, 39 (8), e55
DOI 10.1093/nar/gkr051, PubMed 21300643

Robertson J, Robertson AB, Klungland A (2011)
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
Biochem Biophys Res Commun, 411 (1), 40-3
DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242

Publications 2009

Robertson AB, Klungland A, Rognes T, Leiros I (2009)
DNA repair in mammalian cells: Base excision repair: the long and short of it
Cell Mol Life Sci, 66 (6), 981-93
DOI 10.1007/s00018-009-8736-z, PubMed 19153658

Publications 2006

Matson SW, Robertson AB (2006)
The UvrD helicase and its modulation by the mismatch repair protein MutL
Nucleic Acids Res, 34 (15), 4089-97
DOI 10.1093/nar/gkl450, PubMed 16935885

Robertson A, Pattishall SR, Matson SW (2006)
The DNA binding activity of MutL is required for methyl-directed mismatch repair in Escherichia coli
J Biol Chem, 281 (13), 8399-408
DOI 10.1074/jbc.M509184200, PubMed 16446358

Robertson AB, Pattishall SR, Gibbons EA, Matson SW (2006)
MutL-catalyzed ATP hydrolysis is required at a post-UvrD loading step in methyl-directed mismatch repair
J Biol Chem, 281 (29), 19949-59
DOI 10.1074/jbc.M601604200, PubMed 16690604

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