Borghild Roald's research group: Fetal and Pregnancy related Pathology Research
Perinatal problems like fetal growth restriction and intrauterine fetal death are mainly related to placental insufficiency. Challenges are to understand the various placental pathology processes leading to insufficiency and their clinical implications to treatment and follow up.
Another perinatal problem is that premature born babies can experience hypoxia due to developmental immaturity in the fetal lungs, with serious complications in the fetal brain. Cochrane reviews have asked for research to explore the cellular and molecular mechanisms in corticosteroid treatment, clinically used to enhance lung maturation by threatening premature birth, - and to search for alternative treatment options. We aim to answer the questions raised by in ovo pharmacologic manipulation in a chicken experimental model.