Kaare M. Gautvik

  • Prof. emeritus

Publications 2020

Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S (2020)
Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
J Bone Miner Res, 35 (6), 1065-1076
DOI 10.1002/jbmr.3974, PubMed 32017184

Olstad OK, Gautvik VT, LeBlanc M, Kvernevik KJ, Utheim TP, Runningen A, Wiig H, Kirkegaard C, Raastad T, Reppe S, Gautvik KM (2020)
Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
Ther Adv Musculoskelet Dis, 12, 1759720X20929443
DOI 10.1177/1759720X20929443, PubMed 32536985

Publications 2019

Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD et al. (2019)
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures
J Bone Miner Res, 34 (10), 1824-1836
DOI 10.1002/jbmr.3803, PubMed 31170332

Publications 2017

Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J et al. (2017)
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density
Ann Rheum Dis, 77 (3), 378-385
DOI 10.1136/annrheumdis-2017-212469, PubMed 29170203

Karabegović I, Maas S, Medina-Gomez C, Zrimšek M, Reppe S, Gautvik KM, Uitterlinden AG, Rivadeneira F, Ghanbari M (2017)
Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD)
Int J Mol Sci, 18 (12)
DOI 10.3390/ijms18122529, PubMed 29186852

Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, Demissie S, Duque G, Maurano MT, Kiel DP, Hsu YH, C J van der Eerden B, Ackert-Bicknell C, Reppe S, Gautvik KM, Raastad T et al. (2017)
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
Nat Commun, 8 (1), 121
DOI 10.1038/s41467-017-00108-3, PubMed 28743860

Reppe S, Datta HK, Gautvik KM (2017)
Omics analysis of human bone to identify genes and molecular networks regulating skeletal remodeling in health and disease
Bone, 101, 88-95
DOI 10.1016/j.bone.2017.04.012, PubMed 28450214

Reppe S, Lien TG, Hsu YH, Gautvik VT, Olstad OK, Yu R, Bakke HG, Lyle R, Kringen MK, Glad IK, Gautvik KM (2017)
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
Epigenetics, 12 (8), 674-687
DOI 10.1080/15592294.2017.1345832, PubMed 28650214

Publications 2016

Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L et al. (2016)
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
J Bone Miner Res, 31 (12), 2085-2097
DOI 10.1002/jbmr.2913, PubMed 27476799

Publications 2015

LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS et al. (2015)
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741

Reppe S, Datta H, Gautvik KM (2015)
The Influence of DNA Methylation on Bone Cells
Curr Genomics, 16 (6), 384-92
DOI 10.2174/1389202916666150817202913, PubMed 27019613

Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM (2015)
Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women
J Bone Miner Res, 30 (2), 249-56
DOI 10.1002/jbmr.2342, PubMed 25155887

Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA, GEFOS Consortium (2015)
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
PLoS One, 10 (12), e0144531
DOI 10.1371/journal.pone.0144531, PubMed 26695485

Publications 2014

Capulli M, Olstad OK, Onnerfjord P, Tillgren V, Muraca M, Gautvik KM, Heinegård D, Rucci N, Teti A (2014)
The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss
J Bone Miner Res, 29 (8), 1833-46
DOI 10.1002/jbmr.2206, PubMed 24616121

Heier MS, Gautvik KM (2014)
What happens in the brain in narcolepsy over time?
Sleep Med, 15 (11), 1427
DOI 10.1016/j.sleep.2014.07.003, PubMed 25194584

Heier MS, Skinningsrud A, Paus E, Gautvik KM (2014)
Increased cerebrospinal fluid levels of nerve cell biomarkers in narcolepsy with cataplexy
Sleep Med, 15 (6), 614-8
DOI 10.1016/j.sleep.2014.02.005, PubMed 24784789

Rucci N, Capulli M, Olstad OK, Önnerfjord P, Tillgren V, Gautvik KM, Heinegård D, Teti A (2014)
The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study
Cancer Lett, 358 (1), 67-75
DOI 10.1016/j.canlet.2014.12.032, PubMed 25529009

Vilming Elgaaen B, Olstad OK, Haug KB, Brusletto B, Sandvik L, Staff AC, Gautvik KM, Davidson B (2014)
Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker
BMC Cancer, 14, 80
DOI 10.1186/1471-2407-14-80, PubMed 24512620

Publications 2013

Heier MS, Gautvik KM, Wannag E, Bronder KH, Midtlyng E, Kamaleri Y, Storsaeter J (2013)
Incidence of narcolepsy in Norwegian children and adolescents after vaccination against H1N1 influenza A
Sleep Med, 14 (9), 867-71
DOI 10.1016/j.sleep.2013.03.020, PubMed 23773727

Jensen K, Brusletto BS, Aass HC, Olstad OK, Kierulf P, Gautvik KM (2013)
Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations
PLoS One, 8 (7), e70721
DOI 10.1371/journal.pone.0070721, PubMed 23936243

Jensen K, Rother MB, Brusletto BS, Olstad OK, Dalsbotten Aass HC, van Zelm MC, Kierulf P, Gautvik KM (2013)
Increased ID2 levels in adult precursor B cells as compared with children is associated with impaired Ig locus contraction and decreased bone marrow output
J Immunol, 191 (3), 1210-9
DOI 10.4049/jimmunol.1203462, PubMed 23825313

Publications 2012

Elgaaen BV, Olstad OK, Sandvik L, Odegaard E, Sauer T, Staff AC, Gautvik KM (2012)
ZNF385B and VEGFA are strongly differentially expressed in serous ovarian carcinomas and correlate with survival
PLoS One, 7 (9), e46317
DOI 10.1371/journal.pone.0046317, PubMed 23029477

Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ et al. (2012)
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Nat Genet, 44 (5), 491-501
DOI 10.1038/ng.2249, PubMed 22504420

Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R et al. (2012)
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
PLoS Genet, 8 (7), e1002718
DOI 10.1371/journal.pgen.1002718, PubMed 22792070

Reppe S, Sachse D, Olstad OK, Gautvik VT, Sanderson P, Datta HK, Berg JP, Gautvik KM (2012)
Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix
Bone, 53 (1), 69-78
DOI 10.1016/j.bone.2012.11.015, PubMed 23195995

Publications 2011

Heier MS, Jansson TS, Gautvik KM (2011)
Cerebrospinal fluid hypocretin 1 deficiency, overweight, and metabolic dysregulation in patients with narcolepsy
J Clin Sleep Med, 7 (6), 653-8
DOI 10.5664/jcsm.1474, PubMed 22171205

Jemtland R, Holden M, Reppe S, Olstad OK, Reinholt FP, Gautvik VT, Refvem H, Frigessi A, Houston B, Gautvik KM (2011)
Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype
J Bone Miner Res, 26 (8), 1793-801
DOI 10.1002/jbmr.396, PubMed 21452281

Publications 2010

Elgaaen BV, Haug KB, Wang J, Olstad OK, Fortunati D, Onsrud M, Staff AC, Sauer T, Gautvik KM (2010)
POLD2 and KSP37 (FGFBP2) correlate strongly with histology, stage and outcome in ovarian carcinomas
PLoS One, 5 (11), e13837
DOI 10.1371/journal.pone.0013837, PubMed 21079801

Fortunati D, Reppe S, Fjeldheim AK, Nielsen M, Gautvik VT, Gautvik KM (2010)
Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone
Matrix Biol, 29 (7), 594-601
DOI 10.1016/j.matbio.2010.07.001, PubMed 20654714

Jensen K, Schaffer L, Olstad OK, Bechensteen AG, Hellebostad M, Tjønnfjord GE, Kierulf P, Gautvik KM, Osnes LT (2010)
Striking decrease in the total precursor B-cell compartment during early childhood as evidenced by flow cytometry and gene expression changes
Pediatr Hematol Oncol, 27 (1), 31-45
DOI 10.3109/08880010903420687, PubMed 20121553

Kalogeropoulos M, Varanasi SS, Olstad OK, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Birch MA, Datta HK (2010)
Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes
FASEB J, 24 (8), 2893-903
DOI 10.1096/fj.09-148908, PubMed 20354137

Varanasi SS, Olstad OK, Swan DC, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Datta HK (2010)
Skeletal site-related variation in human trabecular bone transcriptome and signaling
PLoS One, 5 (5), e10692
DOI 10.1371/journal.pone.0010692, PubMed 20502692

Publications 2009

Reppe S, Refvem H, Gautvik VT, Olstad OK, Høvring PI, Reinholt FP, Holden M, Frigessi A, Jemtland R, Gautvik KM (2009)
Eight genes are highly associated with BMD variation in postmenopausal Caucasian women
Bone, 46 (3), 604-12
DOI 10.1016/j.bone.2009.11.007, PubMed 19922823

Publications 2008

Pedersen ME, Fortunati D, Nielsen M, Brorson SH, Lekva T, Nissen-Meyer LS, Gautvik VT, Shahdadfar A, Gautvik KM, Jemtland R (2008)
Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro
Bone, 43 (4), 700-7
DOI 10.1016/j.bone.2008.06.006, PubMed 18620088

Publications 2007

Nissen-Meyer LS, Jemtland R, Gautvik VT, Pedersen ME, Paro R, Fortunati D, Pierroz DD, Stadelmann VA, Reppe S, Reinholt FP, Del Fattore A, Rucci N, Teti A, Ferrari S, Gautvik KM (2007)
Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice
J Cell Sci, 120 (Pt 16), 2785-95
DOI 10.1242/jcs.003855, PubMed 17652162

Reppe S, Stilgren L, Abrahamsen B, Olstad OK, Cero F, Brixen K, Nissen-Meyer LS, Gautvik KM (2007)
Abnormal muscle and hematopoietic gene expression may be important for clinical morbidity in primary hyperparathyroidism
Am J Physiol Endocrinol Metab, 292 (5), E1465-73
DOI 10.1152/ajpendo.00487.2006, PubMed 17227961

Publications 2006

Reppe S, Stilgren L, Olstad OK, Brixen K, Nissen-Meyer LS, Gautvik KM, Abrahamsen B (2006)
Gene expression profiles give insight into the molecular pathology of bone in primary hyperparathyroidism
Bone, 39 (1), 189-98
DOI 10.1016/j.bone.2005.12.020, PubMed 16516570

Reseland JE, Reppe S, Larsen AM, Berner HS, Reinholt FP, Gautvik KM, Slaby I, Lyngstadaas SP (2006)
The effect of enamel matrix derivative on gene expression in osteoblasts
Eur J Oral Sci, 114 Suppl 1, 205-11; discussion 254-6, 381-2
DOI 10.1111/j.1600-0722.2006.00333.x, PubMed 16674687

Publications 2005

Fjeldheim AK, Høvring PI, Løseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM (2005)
Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats
Eur J Endocrinol, 152 (5), 791-803
DOI 10.1530/eje.1.01902, PubMed 15879366

Publications 2004

Reppe S, Olstad OK, Rian E, Gautvik VT, Gautvik KM, Jemtland R (2004)
Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
Biochem Biophys Res Commun, 324 (1), 218-23
DOI 10.1016/j.bbrc.2004.09.030, PubMed 15465005

Publications 2003

Matre V, Høvring PI, Fjeldheim AK, Helgeland L, Orvain C, Andersson KB, Gautvik KM, Gabrielsen OS (2003)
The human neuroendocrine thyrotropin-releasing hormone receptor promoter is activated by the haematopoietic transcription factor c-Myb
Biochem J, 372 (Pt 3), 851-9
DOI 10.1042/BJ20030057, PubMed 12628004

Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM (2003)
Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
Anticancer Res, 23 (3B), 2201-16
PubMed 12894494

Publications 2001

Johansen PW, Paulssen RH, Bjøro T, Gautvik KM, Gordeladze JO (2001)
Distinct guanine nucleotide binding protein alpha-subunit receptor coupling in GH cell lines: effects of bromocriptine and hormones on effector enzyme modulation
Cell Physiol Biochem, 11 (6), 339-52
DOI 10.1159/000047820, PubMed 11832659

Johansen PW, Paulssen RH, Bjøro T, Gautvik KM, Gordeladze JO (2001)
Distinct guanine nucleotide binding protein alpha-subunitreceptor coupling in GH cell lines: effects of bromocriptineand hormones on effector enzyme modulation
In Cellular physiology and biochemistry, Karger, Basel, 11(2001)nr 6, s.339-352
BIBSYS 022056629

Publications 2000

Løseth OP, de Lecea L, Calbet M, Danielson PE, Gautvik V, Høvring PI, Walaas SI, Gautvik KM (2000)
Developmental regulation of two isoforms of Ca(2+)/calmodulin-dependent protein kinase I beta in rat brain
Brain Res, 869 (1-2), 137-45
DOI 10.1016/s0006-8993(00)02359-3, PubMed 10865068

Reppe S, Rian E, Jemtland R, Olstad OK, Gautvik VT, Gautvik KM (2000)
Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
J Bone Miner Res, 15 (12), 2402-12
DOI 10.1359/jbmr.2000.15.12.2402, PubMed 11127205

Publications 1999

Høvring PI, Matre V, Fjeldheim AK, Loseth OP, Gautvik KM (1999)
Transcription of the human thyrotropin-releasing hormone receptor gene-analysis of basal promoter elements and glucocorticoid response elements
Biochem Biophys Res Commun, 257 (3), 829-34
DOI 10.1006/bbrc.1999.0545, PubMed 10208868

Jemtland R, Rian E, Olstad OK, Haug E, Bruland OS, Bucht E, Gautvik KM (1999)
Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein
J Bone Miner Res, 14 (6), 904-14
DOI 10.1359/jbmr.1999.14.6.904, PubMed 10352098

Matre V, Høvring PI, Orstavik S, Frengen E, Rian E, Velickovic Z, Murray-McIntosh RP, Gautvik KM (1999)
Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptor
J Neurochem, 72 (1), 40-50
DOI 10.1046/j.1471-4159.1999.0720040.x, PubMed 9886052

Publications 1998

de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG (1998)
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
Proc Natl Acad Sci U S A, 95 (1), 322-7
DOI 10.1073/pnas.95.1.322, PubMed 9419374

Røttingen JA, Thorsby P, Seem C, Gautvik KM (1998)
[Medical research at Norwegian universities]
Tidsskr Nor Laegeforen, 118 (15), 2339-43
PubMed 9691802

Publications 1997

Olstad OK, Reppe S, Loseth OP, Jemtland R, Gautvik KM (1997)
Binding and cyclic AMP stimulation by N-terminally deleted human PTHs (3-84 and 4-84) in a homologous ligand receptor system
J Bone Miner Res, 12 (9), 1348-57
DOI 10.1359/jbmr.1997.12.9.1348, PubMed 9286750

Publications 1996

de Lecea L, Criado JR, Prospero-Garcia O, Gautvik KM, Schweitzer P, Danielson PE, Dunlop CL, Siggins GR, Henriksen SJ, Sutcliffe JG (1996)
A cortical neuropeptide with neuronal depressant and sleep-modulating properties
Nature, 381 (6579), 242-5
DOI 10.1038/381242a0, PubMed 8622767

Gautvik KM, de Lecea L, Gautvik VT, Danielson PE, Tranque P, Dopazo A, Bloom FE, Sutcliffe JG (1996)
Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction
Proc Natl Acad Sci U S A, 93 (16), 8733-8
DOI 10.1073/pnas.93.16.8733, PubMed 8710940

Publications 1995

Mathavan S, Gautvik VT, Rokkones E, Olstad OK, Kareem BN, Maeda S, Gautvik KM (1995)
High-level production of human parathyroid hormone in Bombyx mori larvae and BmN cells using recombinant baculovirus
Gene, 167 (1-2), 33-9
DOI 10.1016/0378-1119(95)00599-4, PubMed 8566802

Olstad OK, Jemtland R, Loseth OP, Bringhurst FR, Gautvik KM (1995)
Expression and characterization of a recombinant human parathyroid hormone partial agonist with antagonistic properties: Gly-hPTH(-1-->+84)
Peptides, 16 (6), 1031-7
DOI 10.1016/0196-9781(95)00069-v, PubMed 8532584

Paulssen RH, Paulssen EJ, Gautvik KM (1995)
Electroporation of rat pituitary cells
Methods Mol Biol, 48, 123-31
DOI 10.1385/0-89603-304-X:123, PubMed 8528385

Rokkones E, Fromm SH, Kareem BN, Klungland H, Olstad OK, Hogset A, Iversen J, Bjoro K, Gautvik KM (1995)
Human parathyroid hormone as a secretory peptide in milk of transgenic mice
J Cell Biochem, 59 (2), 168-76
DOI 10.1002/jcb.240590206, PubMed 8904311

Publications 1994

Gordeladze JO, Johansen PW, Paulssen RH, Paulssen EJ, Gautvik KM (1994)
G-proteins: implications for pathophysiology and disease
Eur J Endocrinol, 131 (6), 557-74
DOI 10.1530/eje.0.1310557, PubMed 7804437

Kareem BN, Rokkones E, Høgset A, Holmgren E, Gautvik KM (1994)
Translocation and processing of various human parathyroid hormone peptides in Escherichia coli are differentially affected by protein-A-signal-sequence mutations
Eur J Biochem, 220 (3), 893-900
DOI 10.1111/j.1432-1033.1994.tb18692.x, PubMed 8143743

Olstad OK, Morrison NE, Jemtland R, Jüppner H, Segre GV, Gautvik KM (1994)
Differences in binding affinities of human PTH(1-84) do not alter biological potency: a comparison between chemically synthesized hormone, natural and mutant forms
Peptides, 15 (7), 1261-5
DOI 10.1016/0196-9781(94)90151-1, PubMed 7854979

Paulssen RH, Johansen PW, Gordeladze JO, Nymoen O, Paulssen EJ, Gautvik KM (1994)
Cell-specific expression and function of adenylyl cyclases in rat pituitary tumour cell lines
Eur J Biochem, 222 (1), 97-103
DOI 10.1111/j.1432-1033.1994.tb18846.x, PubMed 8200359

Rian E, Jemtland R, Olstad OK, Endresen MJ, Grasser WA, Thiede MA, Henriksen T, Bucht E, Gautvik KM (1994)
Parathyroid hormone-related protein is produced by cultured endothelial cells: a possible role in angiogenesis
Biochem Biophys Res Commun, 198 (2), 740-7
DOI 10.1006/bbrc.1994.1107, PubMed 7507670

Rokkones E, Kareem BN, Olstad OK, Høgset A, Schenstrøm K, Hansson L, Gautvik KM (1994)
Expression of human parathyroid hormone in mammalian cells, Escherichia coli and Saccharomyces cerevisiae
J Biotechnol, 33 (3), 293-306
DOI 10.1016/0168-1656(94)90077-9, PubMed 7764740

Steineger HH, Sørensen HN, Tugwood JD, Skrede S, Spydevold O, Gautvik KM (1994)
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells. Hormonal modulation of fatty-acid-induced transcription
Eur J Biochem, 225 (3), 967-74
DOI 10.1111/j.1432-1033.1994.0967b.x, PubMed 7957233

Publications 1993

Jablonski G, Klem KH, Attramadal A, Dahl E, Rønningen H, Gautvik KM, Haug E, Gordeladze JO (1993)
Surgically induced uremia in rats. I: Effect on bone strength and metabolism
Biosci Rep, 13 (5), 275-87
DOI 10.1007/BF01137964, PubMed 8142613

Jablonski G, Nordahl K, Halse J, Dahl E, Aksnes L, Gautvik KM, Gordeladze JO (1993)
PTH-stimulated adenylate cyclase activity and bone histomorphometry in iliac crest biopsies in the evaluation of uremic patients: a pilot study with the use of artificial intelligence
Miner Electrolyte Metab, 19 (6), 351-61
PubMed 8164616

Matre V, Karlsen HE, Wright MS, Lundell I, Fjeldheim AK, Gabrielsen OS, Larhammar D, Gautvik KM (1993)
Molecular cloning of a functional human thyrotropin-releasing hormone receptor
Biochem Biophys Res Commun, 195 (1), 179-85
DOI 10.1006/bbrc.1993.2027, PubMed 8395824

Mortensen B, Gordeladze JO, Haug E, Schjerven L, Gautvik KM (1993)
Relationship between circulating vitamin D3 metabolites and prolactin or growth hormone levels in rat
Pharmacol Toxicol, 72 (3), 188-93
DOI 10.1111/j.1600-0773.1993.tb00314.x, PubMed 8516267

Mortensen BM, Aarseth HP, Ganss R, Haug E, Gautvik KM, Gordeladze JO (1993)
24,25-dihydroxy vitamin D3 treatment inhibits parathyroid-stimulated adenylate cyclase in iliac crest biopsies from uremic patients
Bone, 14 (2), 125-31
DOI 10.1016/8756-3282(93)90238-6, PubMed 8334029

Mortensen BM, Gautvik KM, Gordeladze JO (1993)
Bone turnover in rats treated with 1,25-dihydroxyvitamin D3, 25-hydroxyvitamin D3 or 24,25-dihydroxyvitamin D3
Biosci Rep, 13 (1), 27-39
DOI 10.1007/BF01138176, PubMed 8392394

Mortensen BM, Gordeladze JO, Lyngdal PT, Aarseth HP, Gautvik KM (1993)
Alterations in serum and urine parameters reflecting bone turnover in uremic patients during treatment with 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3
Miner Electrolyte Metab, 19 (2), 78-85
PubMed 8377728

Rian E, Jemtland R, Olstad OK, Gordeladze JO, Gautvik KM (1993)
Synthesis of human parathyroid-hormone-related protein(1-141) in Saccharomyces cerevisiae. A correct amino-terminal processing vital for the hormone's biological activity is obtained by an ubiquitin fusion protein approach
Eur J Biochem, 213 (1), 641-8
DOI 10.1111/j.1432-1033.1993.tb17803.x, PubMed 8386631

Skibeli V, Rokkones E, Gautvik KM (1993)
[Growth hormone and prolactin receptors belong to a new receptor family. Biological and medical aspects]
Tidsskr Nor Laegeforen, 113 (6), 725-30
PubMed 8465339

Sørensen HN, Hvattum E, Paulssen EJ, Gautvik KM, Bremer J, Spydevold O (1993)
Induction of peroxisomal acyl-CoA oxidase by 3-thia fatty acid, in hepatoma cells and hepatocytes in culture is modified by dexamethasone and insulin
Biochim Biophys Acta, 1171 (3), 263-71
DOI 10.1016/0167-4781(93)90064-k, PubMed 8424950

Publications 1992

Kareem BN, Rokkones E, Høgset A, Holmgren E, Gautvik KM (1992)
A method for the evaluation of the efficiency of signal sequences for secretion and correct N-terminal processing of human parathyroid hormone produced in Escherichia coli
Anal Biochem, 204 (1), 26-33
DOI 10.1016/0003-2697(92)90134-s, PubMed 1514692

Olstad OK, Reppe S, Gabrielsen OS, Hartmanis M, Blingsmo OR, Gautvik VT, Haflan AK, Christensen TB, Oyen TB, Gautvik KM (1992)
Isolation and characterization of two biologically active O-glycosylated forms of human parathyroid hormone produced in Saccharomyces cerevisiae. Identification of a new motif for O-glycosylation
Eur J Biochem, 205 (1), 311-9
DOI 10.1111/j.1432-1033.1992.tb16782.x, PubMed 1555591

Paulssen EJ, Paulssen RH, Gautvik KM, Gordeladze JO (1992)
Hypothalamic hormones modulate G protein levels and second messenger responsiveness in GH3 rat pituitary tumour cells
Biochem Pharmacol, 44 (3), 471-7
DOI 10.1016/0006-2952(92)90438-o, PubMed 1354962

Paulssen EJ, Paulssen RH, Gautvik KM, Gordeladze JO (1992)
'Cross-talk' between phospholipase C and adenylyl cyclase involves regulation of G-protein levels in GH3 rat pituitary cells
Cell Signal, 4 (6), 747-55
DOI 10.1016/0898-6568(92)90056-e, PubMed 1489664

Paulssen RH, Paulssen EJ, Gautvik KM, Gordeladze JO (1992)
The thyroliberin receptor interacts directly with a stimulatory guanine-nucleotide-binding protein in the activation of adenylyl cyclase in GH3 rat pituitary tumour cells. Evidence obtained by the use of antisense RNA inhibition and immunoblocking of the stimulatory guanine-nucleotide-binding protein
Eur J Biochem, 204 (1), 413-8
DOI 10.1111/j.1432-1033.1992.tb16651.x, PubMed 1310943

Paulssen RH, Paulssen EJ, Gautvik KM, Gordeladze JO (1992)
Modulation of G proteins and second messenger responsiveness by steroid hormones in GH3 rat pituitary tumour cells
Acta Physiol Scand, 146 (4), 511-8
DOI 10.1111/j.1748-1716.1992.tb09453.x, PubMed 1362854

Wright MS, Gautvik VT, Gautvik KM (1992)
Cloning strategies for peptide hormone receptors
Acta Endocrinol (Copenh), 126 (2), 97-104
DOI 10.1530/acta.0.1260097, PubMed 1311895

Publications 1991

Birkeland KI, Falch JA, Gautvik KM, Gjestvang FT, Holst N, Haug E (1991)
[Determination of intact parathyroid hormone in patients with calcium metabolism disorders]
Tidsskr Nor Laegeforen, 111 (15), 1840-4
PubMed 1853314

Forsberg G, Brobjer M, Holmgren E, Bergdahl K, Persson P, Gautvik KM, Hartmanis M (1991)
Thrombin and H64A subtilisin cleavage of fusion proteins for preparation of human recombinant parathyroid hormone
J Protein Chem, 10 (5), 517-26
DOI 10.1007/BF01025480, PubMed 1799410

Gautvik KM (1991)
Medullary carcinoma of the thyroid. An update of diagnostic and prognostic factors
Scand J Clin Lab Invest Suppl, 206, 85-92
PubMed 1947764

Jemtland R, Rian E, Gautvik KM (1991)
[Malignant humoral hypercalcemia and the parathyroid hormone related protein]
Tidsskr Nor Laegeforen, 111 (14), 1738-42
PubMed 2063384

Parrow VC, Gordeladze JO, Paulssen EJ, Aleström P, Gautvik KM (1991)
Signal transduction alterations in GH(1)2C1 rat pituitary tumour cells following treatment with 5-azacytidine
J Mol Endocrinol, 6 (3), 257-68
DOI 10.1677/jme.0.0060257, PubMed 1715709

Paulssen EJ, Paulssen RH, Haugen TB, Gautvik KM, Gordeladze JO (1991)
Regulation of G protein mRNA levels by thyroliberin, vasoactive intestinal peptide and somatostatin in prolactin-producing rat pituitary adenoma cells
Acta Physiol Scand, 143 (2), 195-201
DOI 10.1111/j.1748-1716.1991.tb09221.x, PubMed 1683738

Paulssen EJ, Paulssen RH, Haugen TB, Gautvik KM, Gordeladze JO (1991)
Cell specific distribution of guanine nucleotide-binding regulatory proteins in rat pituitary tumour cell lines
Mol Cell Endocrinol, 76 (1-3), 45-53
DOI 10.1016/0303-7207(91)90258-t, PubMed 1820976

Publications 1990

Bjøro T, Sand O, Ostberg BC, Gordeladze JO, Torjesen P, Gautvik KM, Haug E (1990)
The mechanisms by which vasoactive intestinal peptide (VIP) and thyrotropin releasing hormone (TRH) stimulate prolactin release from pituitary cells
Biosci Rep, 10 (2), 189-99
DOI 10.1007/BF01116578, PubMed 2162702

Falch JA, Gautvik KM (1990)
[News on treatment of osteoporosis with fluoride]
Tidsskr Nor Laegeforen, 110 (28), 3641
PubMed 2260067

Gautvik KM, Wright M, Karlsen HE, Sand O (1990)
Hormone receptors and cellular signal transduction
Scand J Clin Lab Invest Suppl, 202, 123-6
PubMed 1706109

Høgset A, Blingsmo OR, Gautvik VT, Saether O, Jacobsen PB, Gordeladze JO, Alestrøm P, Gautvik KM (1990)
Expression of human parathyroid hormone in Escherichia coli
Biochem Biophys Res Commun, 166 (1), 50-60
DOI 10.1016/0006-291x(90)91910-k, PubMed 2405851

Klem KH, Jablonski G, Saether O, Jarosz G, Gautvik KM, Gordeladze JO (1990)
1,25-dihydroxyvitamin D-3 and 24,25-dihydroxyvitamin D-3 affect parathormone (PTH) -sensitive adenylate cyclase activity and alkaline phosphatase secretion of osteoblastic cells through different mechanisms of action
Biochim Biophys Acta, 1054 (3), 304-10
DOI 10.1016/0167-4889(90)90101-i, PubMed 2169895

Mortensen B, Gordeladze JO, Aksnes L, Gautvik KM (1990)
Long-term administration of vitamin D3 metabolites alters PTH-responsive osteoblastic adenylate cyclase in rats
Calcif Tissue Int, 46 (5), 339-45
DOI 10.1007/BF02563826, PubMed 2159835

Paulssen RH, Paulssen EJ, Aleström P, Gautvik KM (1990)
Electroporation of rat pituitary (GH) cell lines: optimal parameters and effects on endogenous hormone production
Biochem Biophys Res Commun, 171 (3), 1029-36
DOI 10.1016/0006-291x(90)90787-n, PubMed 2222425

Paulssen RH, Paulssen EJ, Aleström P, Gordeladze JO, Gautvik KM (1990)
Specific antisense RNA inhibition of growth hormone production in differentiated rat pituitary tumour cells
Biochem Biophys Res Commun, 171 (1), 293-300
DOI 10.1016/0006-291x(90)91391-5, PubMed 1697459

Skibeli V, Andersen O, Gautvik KM (1990)
Purification and characterization of Atlantic salmon growth hormone and evidence for charge heterogeneity
Gen Comp Endocrinol, 80 (3), 333-44
DOI 10.1016/0016-6480(90)90181-k, PubMed 2289675

Sørensen HN, Norrheim L, Spydevold O, Gautvik KM (1990)
Uptake and receptor binding of dexamethasone in cultured 7800 C1 hepatoma cells in relation to regulation of cell growth and peroxisomal beta-oxidation
Int J Biochem, 22 (10), 1171-7
DOI 10.1016/0020-711x(90)90117-l, PubMed 2289623

Spydevold O, Sørensen H, Clausen OP, Gautvik KM (1990)
Dexamethasone inhibition of rat hepatoma cell growth and cell cycle traverse is reversed by insulin
Biochim Biophys Acta, 1052 (1), 221-8
DOI 10.1016/0167-4889(90)90080-w, PubMed 2182131

Wright MS, Karlsen HE, Paulssen EJ, Meyerhof W, Høgset A, Gautvik KM (1990)
Different-sized mRNAs from GH4C1 cells induce a TRH-dependent electrical response in Xenopus laevis oocytes
Acta Physiol Scand, 140 (1), 129-34
DOI 10.1111/j.1748-1716.1990.tb08983.x, PubMed 2177312

Publications 1989

Andersen O, Skibeli V, Gautvik KM (1989)
Purification and characterization of Atlantic salmon prolactin
Gen Comp Endocrinol, 73 (3), 354-60
DOI 10.1016/0016-6480(89)90191-3, PubMed 2925076

Gautvik KM, Talle K, Hager B, Jørgensen OG, Aas M (1989)
Early liver metastases in patients with medullary carcinoma of the thyroid gland
Cancer, 63 (1), 175-80
DOI 10.1002/1097-0142(19890101)63:1<175::aid-cncr2820630128>3.0.co;2-9, PubMed 2910415

Gordeladze JO, Björo T, Torjesen PA, Ostberg BC, Haug E, Gautvik KM (1989)
Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi
Eur J Biochem, 183 (2), 397-406
DOI 10.1111/j.1432-1033.1989.tb14941.x, PubMed 2569396

Naess O, Grünfeld TB, Beraki K, Gjøen K, Flikke M, Orstavik I, Paulssen EJ, Gautvik KM (1989)
[Hybridization in situ. A new technic for the demonstration of viruses and gene products in histologic and cytologic specimens]
Tidsskr Nor Laegeforen, 109 (2), 183-5
PubMed 2916194

Parrow VC, Aleström P, Gautvik KM (1989)
5-azacytidine-induced alterations in the GH12C1 cells: effects on cellular morphology, chromosome structure, DNA and protein synthesis
J Cell Sci, 93 ( Pt 3), 533-43
PubMed 2481682

Rokkones E, Alestrøm P, Skjervold H, Gautvik KM (1989)
Microinjection and expression of a mouse metallothionein human growth hormone fusion gene in fertilized salmonid eggs
J Comp Physiol B, 158 (6), 751-8
DOI 10.1007/BF00693013, PubMed 2715458

Skyrud T, Andersen O, Alestrøm P, Gautvik KM (1989)
Effects of recombinant human growth hormone and insulin-like growth factor 1 on body growth and blood metabolites in brook trout (Salvelinus fontinalis)
Gen Comp Endocrinol, 75 (2), 247-55
DOI 10.1016/0016-6480(89)90077-4, PubMed 2680753

Publications 1988

Bjørneboe GE, Bjørneboe A, Johnsen J, Skylv N, Oftebro H, Gautvik KM, Høiseth A, Mørland J, Drevon CA (1988)
Calcium status and calcium-regulating hormones in alcoholics
Alcohol Clin Exp Res, 12 (2), 229-32
DOI 10.1111/j.1530-0277.1988.tb00185.x, PubMed 2837104

Bjøro T, Ostberg BC, Sand O, Torjesen PA, Penman E, Gordeladze JO, Iversen JG, Gautvik KM, Haug E (1988)
Somatostatin inhibits prolactin secretion by multiple mechanisms involving a site of action distal to increased cyclic adenosine 3',5'-monophosphate and elevated cytosolic Ca2+ in rat lactotrophs
Acta Physiol Scand, 133 (3), 271-82
DOI 10.1111/j.1748-1716.1988.tb08408.x, PubMed 2906508

Falch JA, Gautvik KM (1988)
A longitudinal study of pre- and postmenopausal changes in calcium metabolism
Bone, 9 (1), 15-9
DOI 10.1016/8756-3282(88)90022-1, PubMed 3377918

Gordeladze JO, Bjøro T, Ostberg BC, Sand O, Torjesen P, Haug E, Gautvik KM (1988)
Phorbol esters and thyroliberin have distinct actions regarding stimulation of prolactin secretion and activation of adenylate cyclase in rat pituitary tumour cells (GH4C1 cells)
Biochem Pharmacol, 37 (16), 3133-8
DOI 10.1016/0006-2952(88)90311-5, PubMed 2900008

Gordeladze JO, Rur H, Attramadal A, Tveter K, Gautvik KM, Purvis K (1988)
Distribution of Thyroliberin (TRH)- and 12-O-tetradecanoylphorbol 13-acetate (TPA)-activated adenylyl cyclase in normal and neoplastic tissue with special reference to the prostate
Mol Cell Endocrinol, 58 (2-3), 287-90
DOI 10.1016/0303-7207(88)90167-0, PubMed 3145232

Gordeladze JO, Sletholt K, Thorn NA, Gautvik KM (1988)
Hormone-sensitive adenylate cyclase of prolactin-producing rat pituitary adenoma (GH4C1) cells: molecular organization
Eur J Biochem, 177 (3), 665-72
DOI 10.1111/j.1432-1033.1988.tb14421.x, PubMed 2904368

Wright M, Høgset A, Alestrøm P, Gautvik KM (1988)
A 64 kDa protein is a candidate for a thyrotropin-releasing hormone receptor in prolactin-producing rat pituitary tumor cells (GH4C1 cells)
Biochem Biophys Res Commun, 157 (3), 875-82
DOI 10.1016/s0006-291x(88)80956-2, PubMed 2849944

Publications 1987

Bjøro T, Ostberg BC, Sand O, Gordeladze J, Iversen JG, Torjesen PA, Gautvik KM, Haug E (1987)
Vasoactive intestinal peptide and peptide with N-terminal histidine and C-terminal isoleucine increase prolactin secretion in cultured rat pituitary cells (GH4C1) via a cAMP-dependent mechanism which involves transient elevation of intracellular Ca2+
Mol Cell Endocrinol, 49 (2-3), 119-28
DOI 10.1016/0303-7207(87)90205-x, PubMed 2435588

Bjøro T, Torjesen PA, Ostberg BC, Sand O, Iversen JG, Gautvik KM, Haug E (1987)
Bombesin stimulates prolactin secretion from cultured rat pituitary tumour cells (GH4C1) via activation of phospholipase C
Regul Pept, 19 (3-4), 169-82
DOI 10.1016/0167-0115(87)90274-6, PubMed 2829290

Bjøro T, Wiik P, Opstad PK, Gautvik KM, Haug E (1987)
Binding and degradation of vasoactive intestinal peptide in prolactin-producing cultured rat pituitary tumour cells (GH4C1)
Acta Physiol Scand, 130 (4), 609-18
DOI 10.1111/j.1748-1716.1987.tb08183.x, PubMed 2820199

Furu K, Kilvik K, Gautvik KM, Haug E (1987)
The mechanism of [3H]dexamethasone uptake into prolactin producing rat pituitary cells (GH3 cells) in culture
J Steroid Biochem, 28 (6), 587-91
DOI 10.1016/0022-4731(87)90384-0, PubMed 3695511

Gordeladze JO, Mortensen B, Nordal K, Halse J, Dahl E, Aksnes L, Gautvik KM (1987)
The effect of parathyroid hormone (PTH) and 24,25-dihydroxy-vitamin D3 on adenylyl cyclase of iliac crest biopsies: diagnostic and prognostic tool for evaluation and treatment of uremic patients
Scand J Clin Lab Invest Suppl, 186, 13-20
PubMed 3496656

Haug E, Bjøro T, Gautvik KM (1987)
A permissive role for extracellular Ca2+ in regulation of prolactin production by 1,25-dihydroxyvitamin D3 in GH3 pituitary cells
J Steroid Biochem, 28 (4), 385-91
DOI 10.1016/0022-4731(87)91055-7, PubMed 2889849

Sletholt K, Gordeladze J, Haug E, Gautvik KM (1987)
Effects of trifluoperazine on prolactin release and cyclic AMP formation and degradation in GH4C1 pituitary cells
Acta Endocrinol (Copenh), 116 (1), 27-35
DOI 10.1530/acta.0.1160027, PubMed 2821717

Sletholt K, Haug E, Gautvik KM (1987)
On the involvement of cyclic AMP and extracellular Ca2+ in the regulation of hormone release from rat pituitary tumour (GH3) cells in culture
Biosci Rep, 7 (2), 93-105
DOI 10.1007/BF01121872, PubMed 2443198

Sletholt K, Haug E, Gordeladze J, Sand O, Gautvik KM (1987)
Effects of calmodulin antagonists on hormone release and cyclic AMP levels in GH3 pituitary cells
Acta Physiol Scand, 130 (2), 333-43
DOI 10.1111/j.1748-1716.1987.tb08145.x, PubMed 3037857

Sletholt K, Magnusson C, Haug E, Gautvik KM (1987)
Effects of metabolic inhibitors on hormone release, cyclic AMP levels, and oxygen consumption in rat pituitary cells in culture
Acta Endocrinol (Copenh), 115 (1), 96-104
DOI 10.1530/acta.0.1150096, PubMed 3035854

Publications 1986

Gordeladze JO, Gautvik KM (1986)
Hydroxycholecalciferols modulate parathyroid hormone and calcitonin sensitive adenylyl cyclase in bone and kidney of rats. A possible physiological role for 24,25-dihydroxy vitamin D3
Biochem Pharmacol, 35 (6), 899-902
DOI 10.1016/0006-2952(86)90074-2, PubMed 3485429

Gürkan L, Ekeland A, Gautvik KM, Langeland N, Rønningen H, Solheim LF (1986)
Bone changes after castration in rats. A model for osteoporosis
Acta Orthop Scand, 57 (1), 67-70
DOI 10.3109/17453678608993219, PubMed 3962636

Halvorsen JF, Gautvik VT, Gautvik KM (1986)
Improved diagnosis of primary hyperparathyroidism by defining the inverse relationship between serum immunoreactive parathyroid hormone and calcium
Scand J Clin Lab Invest, 46 (5), 435-42
DOI 10.3109/00365518609083695, PubMed 3749790

Iversen JG, Sletholt K, Haug E, Gautvik KM (1986)
On the functional relationship between 45Ca2+ release and prolactin secretion in cultured rat pituitary tumour (GH3) cells
Acta Physiol Scand, 127 (2), 249-55
DOI 10.1111/j.1748-1716.1986.tb07900.x, PubMed 2873712

Johansen PW, Sand O, Iversen JG, Haug E, Gautvik KM (1986)
Effects of bromocriptine on prolactin release, electrical membrane properties and transmembrane Ca2+ fluxes in cultured rat pituitary adenoma cells
Acta Endocrinol (Copenh), 111 (2), 185-92
DOI 10.1530/acta.0.1110185, PubMed 3082096

Paulssen EJ, Aleström P, Johansen BT, Kriz M, Philipson L, Gautvik KM (1986)
Novel prolactin related mRNAs in rat pituitary cells
Biochem Biophys Res Commun, 138 (3), 1015-22
DOI 10.1016/s0006-291x(86)80383-7, PubMed 3753484

Sand O, Jonsson L, Nielsen M, Holm R, Gautvik KM (1986)
Electrophysiological properties of calcitonin-secreting cells derived from human medullary thyroid carcinoma
Acta Physiol Scand, 126 (2), 173-9
DOI 10.1111/j.1748-1716.1986.tb07803.x, PubMed 3705981

Publications 1985

Fauchald P, Gautvik VT, Gautvik KM (1985)
Immunoreactive parathyroid hormone and calcitonin in plasma and ultrafiltrate before and after haemodialysis
Scand J Clin Lab Invest, 45 (3), 229-35
DOI 10.3109/00365518509161000, PubMed 4001828

Haug E, Gautvik KM (1985)
Demonstration and characterization of a 1 alpha,25-(OH)2D3 receptor-like macromolecule in cultured rat pituitary cells
J Steroid Biochem, 23 (5A), 625-35
DOI 10.1016/0022-4731(85)90014-7, PubMed 3001410

Johansen PW, Clausen OP, Haug E, Fossum S, Gautvik KM (1985)
Effects of bromocriptine on cell cycle distribution and cell morphology in cultured rat pituitary adenoma cells
Acta Endocrinol (Copenh), 110 (3), 319-28
DOI 10.1530/acta.0.1100319, PubMed 4072574

Johansen PW, Haug E, Gautvik KM (1985)
Effects of bromocriptine on hormone production and cell growth in cultured rat pituitary cells
Acta Endocrinol (Copenh), 110 (2), 200-6
DOI 10.1530/acta.0.1100200, PubMed 4060970

Kilvik K, Furu K, Haug E, Gautvik KM (1985)
The mechanism of 17 beta-estradiol uptake into prolactin-producing rat pituitary cells (GH3 cells) in culture
Endocrinology, 117 (3), 967-75
DOI 10.1210/endo-117-3-967, PubMed 3926472

Laerum E, Borchgrevink CF, Gautvik KM, Aune S (1985)
The diagnosis, occurrence and clinical aspects of primary hyperparathyroidism in patients with recurrent urolithiasis as registered in general practice
Scand J Prim Health Care, 3 (4), 207-13
DOI 10.3109/02813438509013951, PubMed 4081402

Publications 1984

Bjøro T, Haug E, Sand O, Gautvik KM (1984)
Vasoactive intestinal peptide causes a calcium-dependent stimulation of prolactin secretion in GH4C1 cells
Mol Cell Endocrinol, 37 (1), 41-50
DOI 10.1016/0303-7207(84)90126-6, PubMed 6432604

Gautvik KM, Gordeladze JO, Moxheim E, Gautvik VT (1984)
Peripheral metabolism of parathyroid hormone in patients with primary hyperparathyroidism as judged by immunological and biological studies
Eur Surg Res, 16 Suppl 2, 41-54
DOI 10.1159/000128621, PubMed 6723731

Rui H, Gordeladze JO, Gautvik KM, Purvis K (1984)
Prolactin desensitizes the prostaglandin E1-dependent adenylyl cyclase in the rat prostate gland
Mol Cell Endocrinol, 38 (1), 53-60
DOI 10.1016/0303-7207(84)90144-8, PubMed 6542888

Publications 1983

Ekeland A, Gautvik KM, Underdal T (1983)
Calcitonin producing tumour. Effects on fracture repair and normal bone in rats
Acta Orthop Scand, 54 (5), 760-7
DOI 10.3109/17453678308996626, PubMed 6670496

Gautvik KM, Gautvik VT, Halvorsen JF (1983)
Characterization of the molecular forms of immunoreactive parathyroid hormone in primary hyperparathyroidism and in hyperparathyroidism due to renal failure
Scand J Clin Lab Invest, 43 (7), 553-64
PubMed 6658372

Gautvik KM, Gordeladze JO, Jahnsen T, Haug E, Hansson V, Lystad E (1983)
Thyroliberin receptor binding and adenylyl cyclase activation in cultured prolactin-producing rat pituitary tumor cells (GH cells)
J Biol Chem, 258 (17), 10304-11
PubMed 6309800

Publications 1982

Gautvik KM, Kriz M, Jahnsen T, Haug E, Hansson V (1982)
Relationship between stimulated prolactin release from GH cells and cyclic AMP degradation and formation
Mol Cell Endocrinol, 26 (3), 295-308
DOI 10.1016/0303-7207(82)90118-6, PubMed 6281098

Gautvik KM, Svindahl K, Skretting A, Stenberg B, Myhre L, Ekeland A, Johannesen JV (1982)
Uptake and localization of 131I-labeled anti-calcitonin immunoglobulins in rat medullary thyroid carcinoma tissue
Cancer, 50 (6), 1107-14
DOI 10.1002/1097-0142(19820915)50:6<1107::aid-cncr2820500614>3.0.co;2-j, PubMed 7104951

Haug E, Aakvaag A, Sunde A, Gautvik KM, Eik-Nes KB (1982)
Androgen metabolism and mechanism of action in prolactin secreting rat pituitary cells in culture
J Steroid Biochem, 16 (1), 51-9
DOI 10.1016/0022-4731(82)90143-1, PubMed 6977681

Haug E, Pedersen JI, Gautvik KM (1982)
Effects of vitamin D3 metabolites on production of prolactin and growth hormone in rat pituitary cells
Mol Cell Endocrinol, 28 (1), 65-79
DOI 10.1016/0303-7207(82)90041-7, PubMed 6290291

Myhre L, Ekeland A, Gautvik KM (1982)
Immunochemical and biological characterization of calcitonin originating from transplanted medullary thyroid carcinoma in rats
Acta Endocrinol (Copenh), 99 (3), 397-403
DOI 10.1530/acta.0.0990397, PubMed 7072448

Naess O, Haug E, Attramadal A, Gautvik KM (1982)
Progestin receptors in prolactin and growth hormone producing tumours in rats
Acta Endocrinol (Copenh), 100 (1), 25-30
DOI 10.1530/acta.0.1000025, PubMed 7113584

Sand O, Sletholt K, Gautvik KM, Haug E (1982)
Trifluoperazine blocks calcium-dependent action potentials and inhibits hormone release from rat pituitary tumour cells
Eur J Pharmacol, 86 (2), 177-84
DOI 10.1016/0014-2999(82)90315-6, PubMed 6819156

Publications 1981

Ekeland A, Gautvik KM, Myhre L (1981)
Increase in plasma calcitonin following femoral fracture in rats
Acta Orthop Scand, 52 (5), 513-8
DOI 10.3109/17453678108992140, PubMed 7331786

Gautvik KM, Lystad E (1981)
Demonstration of a heterogenous population of binding sites for thyroliberin in prolactin-producing tumour cells and their possible functional significance
Eur J Biochem, 116 (2), 235-42
DOI 10.1111/j.1432-1033.1981.tb05324.x, PubMed 6265214

Hongslo CF, Myhre L, Flaten O, Johannessen JW, Gautvik KM, Ekeland A (1981)
Effect of dietary calcium on secretion of calcitonin and gastrin in rats with medullary thyroid carcinoma
Acta Endocrinol (Copenh), 97 (3), 376-83
DOI 10.1530/acta.0.0970376, PubMed 7257702

Myhre L, Hongslo CF, Gautvik KM, Ekeland A (1981)
Effect of different calcium intakes on bone mineral composition in rats with a calcitonin secreting tumour
Acta Endocrinol (Copenh), 97 (3), 384-90
DOI 10.1530/acta.0.0970384, PubMed 7257703

Sand O, Ozawa S, Gautvik KM (1981)
Sodium and calcium action potentials in cells derived from a rat medullary thyroid carcinoma
Acta Physiol Scand, 112 (3), 287-91
DOI 10.1111/j.1748-1716.1981.tb06818.x, PubMed 7293797

Publications 1980

Gautvik KM, Iversen JG, Sand O (1980)
On the role of extracellular Ca2+ for prolactin release and adenosine 3':5'-monophosphate formation induced by thyroliberin in cultured rat pituitary cells
Life Sci, 26 (12), 995-1005
DOI 10.1016/0024-3205(80)90122-8, PubMed 6248699

Gautvik KM, Johansen L, Svindahl K, Nustad K, Orstavik TB (1980)
Isolation of rat submandibula kallikreins by using immunoadsorption chromatography
Biochem J, 189 (1), 153-9
DOI 10.1042/bj1890153, PubMed 7006596

Orstavik TB, Gautvik KM, Nustad K (1980)
Intraglandular transport of 125I-glandular kallikrein in the rat submandibular salivary gland
Acta Physiol Scand, 109 (3), 315-23
DOI 10.1111/j.1748-1716.1980.tb06602.x, PubMed 6905637

Sand O, Haug E, Gautvik KM (1980)
Effects of thyroliberin and 4-aminopyridine on action potentials and prolactin release and synthesis in rat pituitary cells in culture
Acta Physiol Scand, 108 (3), 247-52
DOI 10.1111/j.1748-1716.1980.tb06530.x, PubMed 6769299

Tollman RL, Gautvik KM (1980)
Plasma levels of immunoreactive parathyroid hormone in relation to starvation hypocalcaemia in dairy cows
Acta Vet Scand, 21 (4), 457-68
PubMed 7223573

Valnes K, Flaten O, Hanssen LE, Foss OP, Gautvik KM (1980)
Plasma concentration of secretin and gastric secretion following intraduodenal calcium infusion in man
Scand J Gastroenterol, 15 (7), 881-5
DOI 10.3109/00365528009181546, PubMed 7209397

Publications 1979

Gautvik KM, Teig V, Halvorsen JF, Arnesen E, Myhre L, Heimann P, Tollman R (1979)
Development of sequence specific radioimmunoassay of human parathyroid hormone and its use in the diagnosis of hyperparathyroidism
Scand J Clin Lab Invest, 39 (5), 469-78
DOI 10.3109/00365517909106133, PubMed 574982

Jørgensen OG, Ekeland A, Gautvik KM (1979)
Serum tissue concentrations of immunoreactive calcitonin in patients with breast tumours
Acta Endocrinol (Copenh), 92 (3), 522-31
DOI 10.1530/acta.0.0920522, PubMed 517052

Myhre L, Gautvik KM (1979)
The use of region specific radioimmunoassays for characterization of circulating calcitonin in patients with medullary carcinoma of the thyroid gland
Acta Endocrinol (Copenh), 91 (3), 449-61
DOI 10.1530/acta.0.0910449, PubMed 474037

Orstavik TB, Nustad K, Gautvik KM (1979)
Localization of glandular kallikreins and secretion of kallikrein from the major salivary glands of the rat
Adv Exp Med Biol, 120A, 439-50
DOI 10.1007/978-1-4757-0926-1_40, PubMed 386736

Publications 1978

Clausen OP, Gautvik KM, Haug E (1978)
Effects of cortisol, 17beta-estradiol and thyroliberin on prolactin and growth hormone production, cell growth and cell cycle distribution in cultured rat pituitary tumour cells
J Cell Physiol, 94 (2), 205-14
DOI 10.1002/jcp.1040940210, PubMed 413837

Gautvik KM, Haug E, Kriz M (1978)
Formation of guanosine 3',5'-cyclic monophosphate by thyroliberin in cultured rat pituitary cells. A possible role in stimulation of prolactin synthesis
Biochim Biophys Acta, 538 (2), 354-63
DOI 10.1016/0304-4165(78)90363-x, PubMed 202336

Haug E, Gautvik KM (1978)
Effects of sex steroids on growth hormone production in cultured rat pituitary cells
Acta Endocrinol (Copenh), 87 (1), 40-54
DOI 10.1530/acta.0.0870040, PubMed 579534

Haug E, Naess O, Gautvik KM (1978)
Receptors for 17beta-estradiol in prolactin-secreting rat pituitary cells
Mol Cell Endocrinol, 12 (1), 81-95
DOI 10.1016/0303-7207(78)90103-x, PubMed 569089

Nustad K, Orstavik TB, Gautvik KM, Pierce JV (1978)
Glandular kallikreins
Gen Pharmacol, 9 (1), 1-9
DOI 10.1016/0306-3623(78)90049-6, PubMed 346434

Roch-Norlund AE, Horn RS, Gautvik KM, Walaas E, Walaas O (1978)
Effect of epinephrine and insulin on adenosine 3'5'-cyclic monophosphate--dependent protein kinase in human skeletal muscle in vivo
Horm Metab Res, 10 (3), 208-13
DOI 10.1055/s-0028-1093436, PubMed 208940

Wiberg T, Vaage J, Bjertnaes L, Hauge A, Gautvik KM (1978)
Prostaglandin content in blood and lung tissue during alveolar hypoxia
Acta Physiol Scand, 102 (2), 181-90
DOI 10.1111/j.1748-1716.1978.tb06061.x, PubMed 343502

Publications 1977

Bang S, Gautvik KM (1977)
Inhibition of prolactin secretion and synthesis by dopamine, noradrenaline and pilocarpine in cultured rat pituitary tumour cells
Acta Pharmacol Toxicol (Copenh), 41 (4), 317-27
DOI 10.1111/j.1600-0773.1977.tb02671.x, PubMed 411328

Clausen OP, Gautvik KM, Lindmo T (1977)
Cell cycle distributions, growth characteristics, and variation in prolactin and growth hormone production in cultured rat pituitary cells
Virchows Arch B Cell Pathol, 23 (3), 195-207
DOI 10.1007/BF02889131, PubMed 403669

Fossum S, Gautvik KM (1977)
Stereological and biochemical analysis of prolactin and growth hormone secreting rat pituitary cells in culture. Stereology combined with non-parametrical statistics
Cell Tissue Res, 184 (2), 169-78
DOI 10.1007/BF00223066, PubMed 411574

Gautvik KM, Haug E, Fossum S, Kriz M, Bang S, Rapley J (1977)
Tidsskr Nor Laegeforen, 97 (16), 839-43
PubMed 195364

Gautvik KM, Walaas E, Walaas O (1977)
Effect of thyroliberin on the concentration of adenosine 3':5'-phosphate and on the activity of adenosine 3':5'-phosphate-dependent protein kinase in prolactin-producing cells in culture
Biochem J, 162 (2), 379-86
DOI 10.1042/bj1620379, PubMed 192221

Haug E, Tjernshaugen H, Gautvik KM (1977)
Variations in prolactin and growth hormone production during cellular growth in clonal strains of rat pituitary cells
J Cell Physiol, 91 (1), 15-29
DOI 10.1002/jcp.1040910103, PubMed 404302

Normann T, Gautvik KM (1977)
Medullary carcinoma of the thyroid gland in Norway. Serum calcitonin in 300 relatives of 43 patients
Ann Chir Gynaecol, 66 (4), 187-94
PubMed 907311

Normann T, Normann E, Schrumpf E, Gautvik KM (1977)
Secretion of calcitonin and gastrin in rats with transplanted medullary thyroid carcinoma
Acta Pathol Microbiol Scand A, 85A (1), 63-72
DOI 10.1111/j.1699-0463.1977.tb03869.x, PubMed 835355

Orstavik TB, Gautvik KM (1977)
Regulation of salivary kallikrein secretion in submandibular gland
Acta Physiol Scand, 100 (1), 33-44
DOI 10.1111/j.1748-1716.1977.tb05919.x, PubMed 899827

Proud D, Bailey GS, Nustad K, Gautvik KM (1977)
The immunological similarity of rat glandular kallikreins
Biochem J, 167 (3), 835-8
DOI 10.1042/bj1670835, PubMed 414745

Publications 1976

Brandtzaeg P, Gautvik KM, Nustad K, Pierce JV (1976)
Rat submandibular gland kallikreins: purification and cellular localization
Br J Pharmacol, 56 (2), 155-67
DOI 10.1111/j.1476-5381.1976.tb07438.x, PubMed 1252668

Dannies PS, Gautvik KM, Tashjian AH (1976)
A possible role of cyclic AMP in mediating the effects of thyrotropin-releasing hormone on prolactin release and on prolactin and growth hormone synthesis in pituitary cells in culture
Endocrinology, 98 (5), 1147-59
DOI 10.1210/endo-98-5-1147, PubMed 177274

Gautvik KM, Fossum S (1976)
Basal and thyroliberin-stimulated prolactin synthesis in single-cell cultures and in populations of rat pituitary cells
Biochem J, 158 (1), 119-25
DOI 10.1042/bj1580119, PubMed 822844

Gautvik KM, Kriz M (1976)
Stimulation of prolactin synthesis and of adenosine 3':5'-cyclic phosphate formation by prostaglandins and thyroliberin in cultured rat pituitary cells
Biochem J, 156 (1), 111-7
DOI 10.1042/bj1560111, PubMed 182137

Gautvik KM, Kriz M (1976)
Measurements of prolactin and growth hormone synthesis and secretion by rat pituitary cells in culture
Endocrinology, 98 (2), 344-51
DOI 10.1210/endo-98-2-344, PubMed 942913

Gautvik KM, Kriz M (1976)
Effects of prostaglandins on prolactin and growth hormone synthesis and secretion in cultured rat pituitary cells
Endocrinology, 98 (2), 352-8
DOI 10.1210/endo-98-2-352, PubMed 813992

Gautvik KM, Kriz M, Fossum S (1976)
A micro-analytical method for measurement of prolactin synthesis in individually cultured rat pituitary cells
Anal Biochem, 74 (1), 52-61
DOI 10.1016/0003-2697(76)90309-2, PubMed 962083

Gautvik KM, Normann T, Teig V, Wille SO, Brennhovd IO, Christensen I (1976)
Radioimmunoassay of human calcitonin in serum and tissue from healthy individuals and patients with medullary carcinoma of the thyroid gland
Scand J Clin Lab Invest, 36 (4), 323-9
PubMed 959750

Haug E, Gautvik KM (1976)
Effects of sex steroids on prolactin secreting rat pituitary cells in culture
Endocrinology, 99 (6), 1482-9
DOI 10.1210/endo-99-6-1482, PubMed 826392

Haug E, Gautvik KM (1976)
Radioimmunoassay of rat prolactin and its use in measuring prolactin production by cultured pituitary cells
Acta Endocrinol (Copenh), 82 (2), 282-97
DOI 10.1530/acta.0.0820282, PubMed 818861

Normann T, Gautvik KM, Johannessen JV, Brennhovd IO (1976)
Medullary carcinoma of the thyroid in Norway. Clinical course and endocrinological aspects
Acta Endocrinol (Copenh), 83 (1), 71-85
DOI 10.1530/acta.0.0830071, PubMed 989224

Normann T, Johannessen JV, Gautvik KM, Olsen BR, Brennhovd IO (1976)
Medullary carcinoma of the thyroid. Diagnostic problems
Cancer, 38 (1), 366-77
DOI 10.1002/1097-0142(197607)38:1<366::aid-cncr2820380153>3.0.co;2-r, PubMed 947528

Tjernshaugen H, Gautvik KM (1976)
Nucleotidase activity in regenerating liver and in clonal strains of hepatoma and pituitary cells in culture
J Cell Physiol, 88 (1), 13-22
DOI 10.1002/jcp.1040880103, PubMed 177432

Publications 1974

Gautvik KM, Kriz M (1974)
Release of kallikrein from isolated cellular organelles of the rat submandibular salivary gland
Acta Physiol Scand, 92 (1), 95-102
DOI 10.1111/j.1748-1716.1974.tb05725.x, PubMed 4370331

Gautvik KM, Tashjian AH (1974)
Human medullary thyroid carcinoma: control of calcitonin secretion in vivo and in tissue culture
Horm Metab Res, 6 (1), 70-3
DOI 10.1055/s-0028-1093887, PubMed 4362123

Gautvik KM, Tashjian AH, Kourides IA, Weintraub BD, Graeber CT, Maloof F, Suzuki K, Zuckerman JE (1974)
Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling
N Engl J Med, 290 (21), 1162-5
DOI 10.1056/NEJM197405232902103, PubMed 4207375

Publications 1973

Gautvik KM (1973)
[Calcitonin and its significance for the diagnosis of medullary carcinoma of the thyroid]
Tidsskr Nor Laegeforen, 93 (15), 1143-8
PubMed 4584540

Gautvik KM, Hoyt RF, Tashjian AH (1973)
Effects of colchicine and 2-Br-alpha-ergocryptine-methane-sulfonate (CB 154) on the release of prolactin and growth hormone by functional pituitary tumor cells in culture
J Cell Physiol, 82 (3), 401-9
DOI 10.1002/jcp.1040820310, PubMed 4204326

Gautvik KM, Tashjian AH (1973)
Effects of Ca ++ and Mg ++ on secretion and synthesis of growth hormone and prolactin by clonal strains of pituitary cell in culture
Endocrinology, 92 (2), 573-83
DOI 10.1210/endo-92-2-573, PubMed 4682868

Gautvik KM, Tashjian AH (1973)
Effects of cations and colchicine on the release of prolactin and growth hormone by functional pituitary tumor cells in culture
Endocrinology, 93 (4), 793-9
DOI 10.1210/endo-93-4-793, PubMed 4199493

Gautvik KM, Weintraub BD, Graeber CT, Maloof F, Zuckerman JE, Tashjian AH (1973)
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women
J Clin Endocrinol Metab, 37 (1), 135-9
DOI 10.1210/jcem-37-1-135, PubMed 4715289

Publications 1972

Gautvik KM, Kriz M, Lund-Larsen K (1972)
Plasma-kinins and adrenergic vasodilatation in the submandibular salivary gland of the cat
Acta Physiol Scand, 86 (3), 419-26
DOI 10.1111/j.1748-1716.1972.tb05347.x, PubMed 4638704

Gautvik KM, Kriz M, Lund-Larsen K (1972)
Effects of alterations in calcium concentrations on secretion and protein synthesis in cat submandibular salivary gland
Acta Physiol Scand, 85 (3), 418-27
DOI 10.1111/j.1748-1716.1971.tb05281.x, PubMed 4627350

Gautvik KM, Nustad K, Vystyd J (1972)
Kininogenase activity in the stimulated submandibular salivary gland in cats
Acta Physiol Scand, 85 (4), 438-45
DOI 10.1111/j.1748-1716.1972.tb05277.x, PubMed 5074159

Publications 1971

Gautvik KM (1971)
[Regulation of gastric blood flow]
Tidsskr Nor Laegeforen, 91 (24), 1739-44
PubMed 4939090

Gautvik KM (1971)
[Building up of plasmakinin in pathologic conditions]
Nord Med, 85 (13), 389-95
PubMed 5313821

Publications 1970

Gautvik KM, Hilton SM, Torres SH (1970)
Consumption of kininogen in the submandibular salivary gland when activated by chorda stimulation
J Physiol, 211 (1), 49-61
DOI 10.1113/jphysiol.1970.sp009265, PubMed 5500998

Publications 1969

Gautvik KM, Nustad K, Vystyd J (1969)
Kininogenase activity in the stimulated submandibular salivary gland in cat
Scand J Clin Lab Invest Suppl, 107, 101-2
PubMed 5375718

Publications 1968

Gautvik KM, Hilton SM, Torres SH (1968)
Consumption of the plasma substrate for glandular kallikrein on activation of the submandibular salivary gland
J Physiol, 197 (1), 22P-23P
PubMed 5675049

Publications 1967

Gautvik KM, Rugstad HE (1967)
Kinin formation and kininogen depletion in rats after intravenous injection of ellagic acid
Br J Pharmacol Chemother, 31 (3), 390-400
DOI 10.1111/j.1476-5381.1967.tb00406.x, PubMed 4966318

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