Jostein Dahle from Trond Stokke's group at the Department of Radiation Biology has become a partner in the new four-year European integrated project NOTE (Non-targeted effects of ionising radiation), which was launced by a kick-off meeting held in Espoo in Finland September 11-14. The project aims to expand the current understanding of health effects caused by low-level doses of ionising radiation.
The NOTE project brings together 19 major European and Canadian groups involved in investigaion of non-targeted effects in cellular, tissue and animal models.
The role of Jostein Dahle and co-workers is to investigate non-targeted effects of alpha particle radiation on cells in culture, approaching the subject from two angles: experiments and mathematical modeling.
Grindedal EM, Zucknick M, Stormorken A, Rønne E, Tandstad NM, Isaacs WB, Axcrona K, Mæhle L(2024) Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome Prostate(in press) DOI 10.1002/pros.24711, PubMed 38629217
Meriranta L, Sorri S, Huse K, Liu X, Spasevska I, Zafar S, Chowdhury I, Dufva O, Sahlberg E, Tandaric L, Karjalainen-Lindsberg ML, Hyytiainen M, Varjosalo M, Myklebust JH, Leppa S(2024) Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-cell Lymphoma Blood Cancer Discov(in press) DOI 10.1158/2643-3230.BCD-23-0182, PubMed 38630892
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman MW, Eder T, Abdallah DI, Maurer B, Wagner C, Schönefeldt S, Spirk K, Pichler A, Pemovska T, Schweicker C, Pölöske D, Hubanic E, Jungherz D, Müller TA, Aung MMK, Orlova A, Pham HTT, Zimmel K, Krausgruber T, Bock Cet al.(2024) Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia J Clin Invest, 134(8) DOI 10.1172/JCI168536, PubMed 38618957