Gunnveig Grødeland
- Senior researcher and Group leader; PhD
- +47 23 07 42 23
Publications 2024
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Nat Commun, 15 (1), 850
DOI 10.1038/s41467-024-44889-w, PubMed 38346952
T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study
EBioMedicine, 108, 105317 (in press)
DOI 10.1016/j.ebiom.2024.105317, PubMed 39260039
Incidence and outcome of COVID-19 following vaccine and hybrid immunity in patients on immunosuppressive therapy: identification of protective post-immunisation anti-RBD antibody levels in a prospective cohort study
RMD Open, 10 (2)
DOI 10.1136/rmdopen-2023-003545, PubMed 38599653
Publications 2023
Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
EBioMedicine, 97, 104833
DOI 10.1016/j.ebiom.2023.104833, PubMed 37844534
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
J Virol, 97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241
Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
DOI 10.1038/s41541-023-00600-6, PubMed 36697432
Publications 2022
Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study
Lancet Rheumatol, 5 (1), e36-e46
DOI 10.1016/S2665-9913(22)00330-7, PubMed 36415604
The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
Cancer Res Commun, 2 (4), 233-245
DOI 10.1158/2767-9764.CRC-22-0027, PubMed 36873622
The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls-a prospective cohort study
BMC Med, 20 (1), 378
DOI 10.1186/s12916-022-02587-8, PubMed 36199139
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
Cell Rep, 39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357
The Highly Productive Thermothelomyces heterothallica C1 Expression System as a Host for Rapid Development of Influenza Vaccines
Vaccines (Basel), 10 (2)
DOI 10.3390/vaccines10020148, PubMed 35214607
[Menstrual abnormalities after COVID-19 vaccination]
Tidsskr Nor Laegeforen, 142 (9)
DOI 10.4045/tidsskr.22.0217, PubMed 35699538
Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy
RMD Open, 8 (2)
DOI 10.1136/rmdopen-2022-002417, PubMed 36328399
Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy
Arthritis Rheumatol, 74 (8), 1321-1332
DOI 10.1002/art.42153, PubMed 35507355
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405
[Efficacy of three doses of COVID-19 vaccine]
Tidsskr Nor Laegeforen, 142 (5)
DOI 10.4045/tidsskr.22.0096, PubMed 35324133
Publications 2021
Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief
Front Immunol, 12, 747032
DOI 10.3389/fimmu.2021.747032, PubMed 34691056
[The vaccines can keep up with the SARS-CoV-2 mutations]
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.21.0080, PubMed 33624975
Nafamostat-Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2
Viruses, 13 (9)
DOI 10.3390/v13091768, PubMed 34578348
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections
Viruses, 13 (12)
DOI 10.3390/v13122489, PubMed 34960758
Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study
Lancet Rheumatol, 4 (3), e177-e187
DOI 10.1016/S2665-9913(21)00394-5, PubMed 34977602
SARS-CoV-2 neutralising antibody testing in Europe: towards harmonisation of neutralising antibody titres for better use of convalescent plasma and comparability of trial data
Euro Surveill, 26 (27)
DOI 10.2807/1560-7917.ES.2021.26.27.2100568, PubMed 34240697
[How effective is the COVID-19 vaccine for older persons?]
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0748, PubMed 34911279
Matrix M Adjuvanted H5N1 Vaccine Elicits Broadly Neutralizing Antibodies and Neuraminidase Inhibiting Antibodies in Humans That Correlate With In Vivo Protection
Front Immunol, 12, 747774
DOI 10.3389/fimmu.2021.747774, PubMed 34887855
Publications 2020
Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin
Front Immunol, 11, 431
DOI 10.3389/fimmu.2020.00431, PubMed 32269566
Status of COVID-19 vaccine development
Tidsskr Nor Laegeforen, 140 (13)
DOI 10.4045/tidsskr.20.0676, PubMed 32998488
Publications 2019
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine, 37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800
Publications 2018
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
J Immunol, 200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690
Publications 2017
A DNA Vaccine That Targets Hemagglutinin to Antigen-Presenting Cells Protects Mice against H7 Influenza
J Virol, 91 (23)
DOI 10.1128/JVI.01340-17, PubMed 28931687
Publications 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
J Immunol, 197 (9), 3575-3585
DOI 10.4049/jimmunol.1600893, PubMed 27671110
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
Front Immunol, 7, 321
DOI 10.3389/fimmu.2016.00321, PubMed 27602032
Publications 2015
Targeting of nucleoprotein to chemokine receptors by DNA vaccination results in increased CD8(+)-mediated cross protection against influenza
Vaccine, 33 (49), 6988-96
DOI 10.1016/j.vaccine.2015.08.094, PubMed 26387432
Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules
Expert Rev Vaccines, 14 (6), 805-14
DOI 10.1586/14760584.2015.1029919, PubMed 25818107
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
Front Immunol, 6, 367
DOI 10.3389/fimmu.2015.00367, PubMed 26257735
Publications 2014
Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus
Eur J Immunol, 45 (2), 624-35
DOI 10.1002/eji.201445080, PubMed 25410055
Publications 2013
DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza
J Immunol, 191 (6), 3221-31
DOI 10.4049/jimmunol.1300504, PubMed 23956431
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype
PLoS One, 8 (11), e80008
DOI 10.1371/journal.pone.0080008, PubMed 24244595
Publications 2010
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines
Vaccine, 29 (2), 191-9
DOI 10.1016/j.vaccine.2010.10.057, PubMed 21055498
Publications 2009
Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro
Chronobiol Int, 26 (2), 242-57
DOI 10.1080/07420520902766025, PubMed 19212839
Publications 2007
Induction of gene expression and clock-related proteins in serum shocked primary human mesenchymal stem cells in culture
[G. Grødeland], Bergen, VIII, 72 bl.
BIBSYS 071274251