Sebastian Patzke

  • Project leader, Senior scientist; PhD
  • +47 22 78 14 80 / 995 90 768
 

Publications 2019

Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255

Publications 2018

Hompland T, Hole KH, Ragnum HB, Aarnes EK, Vlatkovic L, Lie AK, Patzke S, Brennhovd B, Seierstad T, Lyng H (2018)
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958

Shearer RF, Frikstad KM, McKenna J, McCloy RA, Deng N, Burgess A, Stokke T, Patzke S, Saunders DN (2018)
The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia
Mol Biol Cell, 29 (13), 1542-1554
DOI 10.1091/mbc.E17-04-0248, PubMed 29742019

Publications 2017

Olsen CE, Sellevold S, Theodossiou T, Patzke S, Berg K (2017)
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin
Photodiagnosis Photodyn Ther, 20, 35-47
DOI 10.1016/j.pdpdt.2017.08.010, PubMed 28838761

Publications 2016

Hasvold G, Lund-Andersen C, Lando M, Patzke S, Hauge S, Suo Z, Lyng H, Syljuåsen RG (2016)
Hypoxia-induced alterations of G2 checkpoint regulators
Mol Oncol, 10 (5), 764-73
DOI 10.1016/j.molonc.2015.12.015, PubMed 26791779

Publications 2015

Berstad MB, Cheung LH, Berg K, Peng Q, Fremstedal AS, Patzke S, Rosenblum MG, Weyergang A (2015)
Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
Oncogene, 34 (44), 5582-92
DOI 10.1038/onc.2015.15, PubMed 25684137

Dale Rein I, Solberg Landsverk K, Micci F, Patzke S, Stokke T (2015)
Replication-induced DNA damage after PARP inhibition causes G2 delay, and cell line-dependent apoptosis, necrosis and multinucleation
Cell Cycle, 14 (20), 3248-60
DOI 10.1080/15384101.2015.1085137, PubMed 26312527

Dale Rein I, Stokke C, Jalal M, Myklebust JH, Patzke S, Stokke T (2015)
New distinct compartments in the G2 phase of the cell cycle defined by the levels of γH2AX
Cell Cycle, 14 (20), 3261-9
DOI 10.1080/15384101.2015.1087617, PubMed 26317799

Repetto-Llamazares AH, Larsen RH, Patzke S, Fleten KG, Didierlaurent D, Pichard A, Pouget JP, Dahle J (2015)
Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma
PLoS One, 10 (6), e0128816
DOI 10.1371/journal.pone.0128816, PubMed 26066655

Sternemalm J, Geimer S, Frikstad KA, Schink KO, Stokke T, Patzke S (2015)
CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
PLoS One, 10 (8), e0134789
DOI 10.1371/journal.pone.0134789, PubMed 26241740

Publications 2014

Lund-Andersen C, Patzke S, Nähse-Kumpf V, Syljuåsen RG (2014)
PLK1-inhibition can cause radiosensitization or radioresistance dependent on the treatment schedule
Radiother Oncol, 110 (2), 355-61
DOI 10.1016/j.radonc.2013.12.014, PubMed 24502970

Sternemalm J, Russnes HG, Zhao X, Risberg B, Nord S, Caldas C, Børresen-Dale AL, Stokke T, Patzke S (2014)
Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
Br J Cancer, 111 (2), 326-38
DOI 10.1038/bjc.2014.297, PubMed 24901235

Publications 2012

Beck H, Nähse-Kumpf V, Larsen MS, O'Hanlon KA, Patzke S, Holmberg C, Mejlvang J, Groth A, Nielsen O, Syljuåsen RG, Sørensen CS (2012)
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Mol Cell Biol, 32 (20), 4226-36
DOI 10.1128/MCB.00412-12, PubMed 22907750

Publications 2011

Landsverk KS, Patzke S, Rein ID, Stokke C, Lyng H, De Angelis PM, Stokke T (2011)
Three independent mechanisms for arrest in G2 after ionizing radiation
Cell Cycle, 10 (5), 819-29
DOI 10.4161/cc.10.5.14968, PubMed 21325885

Publications 2010

Patzke S, Redick S, Warsame A, Murga-Zamalloa CA, Khanna H, Doxsey S, Stokke T (2010)
CSPP is a ciliary protein interacting with Nephrocystin 8 and required for cilia formation
Mol Biol Cell, 21 (15), 2555-67
DOI 10.1091/mbc.e09-06-0503, PubMed 20519441

Publications 2007

Hauge H, Patzke S, Aasheim HC (2007)
Characterization of the FAM110 gene family
Genomics, 90 (1), 14-27
DOI 10.1016/j.ygeno.2007.03.002, PubMed 17499476

Publications 2006

Patzke S, Stokke T, Aasheim HC (2006)
CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization
J Cell Physiol, 209 (1), 199-210
DOI 10.1002/jcp.20725, PubMed 16826565

Ree AH, Stokke T, Bratland A, Patzke S, Nome RV, Folkvord S, Meza-Zepeda LA, Flatmark K, Fodstad O, Andersson Y (2006)
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
Anticancer Res, 26 (3A), 1909-16
PubMed 16827124

Sivertsen EA, Galteland E, Mu D, Holte H, Meza-Zepeda L, Myklebost O, Patzke S, Smeland EB, Stokke T (2006)
Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas
Leukemia, 20 (3), 539-42
DOI 10.1038/sj.leu.2404094, PubMed 16437153

Publications 2005

Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Aasheim HC (2005)
Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
Oncogene, 24 (7), 1159-73
DOI 10.1038/sj.onc.1208267, PubMed 15580290

Aasheim HC, Patzke S, Hjorthaug HS, Finne EF (2005)
Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis
Biochim Biophys Acta, 1723 (1-3), 1-7
DOI 10.1016/j.bbagen.2005.01.011, PubMed 15777695

Publications 2004

Hauge H, Patzke S, Delabie J, Aasheim HC (2004)
Characterization of a novel immunoglobulin-like domain containing receptor
Biochem Biophys Res Commun, 323 (3), 970-8
DOI 10.1016/j.bbrc.2004.08.188, PubMed 15381095

Publications 2002

Patzke S, Lindeskog M, Munthe E, Aasheim HC (2002)
Characterization of a novel human endogenous retrovirus, HERV-H/F, expressed in human leukemia cell lines
Virology, 303 (1), 164-73
DOI 10.1006/viro.2002.1615, PubMed 12482668

Schäfer MA, Tastan AO, Patzke S, Blaha G, Spahn CM, Wilson DN, Nierhaus KH (2002)
Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit
J Biol Chem, 277 (21), 19095-105
DOI 10.1074/jbc.M108902200, PubMed 11867615

Publications 2000

Polacek N, Patzke S, Nierhaus KH, Barta A (2000)
Periodic conformational changes in rRNA: monitoring the dynamics of translating ribosomes
Mol Cell, 6 (1), 159-71
PubMed 10949037

Publications 1998

Dabrowski M, Spahn CM, Schäfer MA, Patzke S, Nierhaus KH (1998)
Protection patterns of tRNAs do not change during ribosomal translocation
J Biol Chem, 273 (49), 32793-800
DOI 10.1074/jbc.273.49.32793, PubMed 9830024

Apr 26, 2004 Page visits: 12917