Publications 2024

Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K et al. (2024)
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
Am J Hum Genet, 111 (3), 594-613
DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010

Radulovic M, Stenmark H (2024)
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545

Wenzel EM, Pedersen NM, Elfmark LA, Wang L, Kjos I, Stang E, Malerød L, Brech A, Stenmark H, Raiborg C (2024)
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434

Zhen Y, Stenmark H (2024)
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880

Publications 2023

Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
J Immunol, 211 (9), 1348-1358
DOI 10.4049/jimmunol.2300406, PubMed 37737664

Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
Protrudin-mediated ER-endosome contact sites promote phagocytosis
Cell Mol Life Sci, 80 (8), 216
DOI 10.1007/s00018-023-04862-0, PubMed 37468729

Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525

Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
Removal of hypersignaling endosomes by simaphagy
Autophagy, 1-23 (in press)
DOI 10.1080/15548627.2023.2267958, PubMed 37840274

Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481

Nähse V, Schink KO, Stenmark H (2023)
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386

Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
Cell Mol Life Sci, 80 (8), 235
DOI 10.1007/s00018-023-04864-y, PubMed 37523003

Zhen Y, Stenmark H (2023)
Autophagosome Biogenesis
Cells, 12 (4)
DOI 10.3390/cells12040668, PubMed 36831335

Zhen Y, Stenmark H (2023)
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066

Publications 2022

Migliano SM, Stenmark H (2022)
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056

Migliano SM, Wenzel EM, Stenmark H (2022)
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
Curr Opin Cell Biol, 75, 102062
DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976

Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828

Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553

Wenzel EM, Elfmark LA, Stenmark H, Raiborg C (2022)
ER as master regulator of membrane trafficking and organelle function
J Cell Biol, 221 (10)
DOI 10.1083/jcb.202205135, PubMed 36108241

Publications 2021

Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217

Janssen M, Stenmark H, Carlson A (2021)
Divalent ligand-monovalent molecule binding
Soft Matter, 17 (21), 5375-5383
DOI 10.1039/d1sm00070e, PubMed 33961000

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
DOI 10.1242/jcs.250670, PubMed 33468622

Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942

Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 17 (4), 1046-1048
DOI 10.1080/15548627.2021.1887548, PubMed 33629888

Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
J Cell Sci, 134 (14)
DOI 10.1242/jcs.258495, PubMed 34109410

Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
Proc Natl Acad Sci U S A, 118 (28)
DOI 10.1073/pnas.2024596118, PubMed 34244439

Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904

Publications 2020

Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
Proc Natl Acad Sci U S A, 117 (46), 28614-28624
DOI 10.1073/pnas.2014228117, PubMed 33139578

Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
J Cell Sci, 133 (13)
DOI 10.1242/jcs.244467, PubMed 32546530

Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
J Cell Biol, 219 (8)
DOI 10.1083/jcb.202003063, PubMed 32479595

Radulovic M, Stenmark H (2020)
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793

Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372

Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (8), 868-879
DOI 10.1038/s41590-020-0730-5, PubMed 32690950

Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
Author Correction: STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (11), 1468-1469
DOI 10.1038/s41590-020-0803-5, PubMed 32929276

Publications 2019

Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279

Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533

Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
Elife, 8
DOI 10.7554/eLife.51063, PubMed 31868590

Scorrano L, De Matteis MA, Emr S, Giordano F, Hajnóczky G, Kornmann B, Lackner LL, Levine TP, Pellegrini L, Reinisch K, Rizzuto R, Simmen T, Stenmark H, Ungermann C, Schuldiner M (2019)
Coming together to define membrane contact sites
Nat Commun, 10 (1), 1287
DOI 10.1038/s41467-019-09253-3, PubMed 30894536

Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
PLoS Pathog, 15 (3), e1007684
DOI 10.1371/journal.ppat.1007684, PubMed 30883606

Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
Nat Commun, 10 (1), 2850
DOI 10.1038/s41467-019-10794-w, PubMed 31253801

Sneeggen M, Schink KO, Stenmark H (2019)
Tumor suppression by control of matrix metalloproteinase recycling
Mol Cell Oncol, 6 (6), e1646606
DOI 10.1080/23723556.2019.1646606, PubMed 31692886

Vietri M, Radulovic M, Stenmark H (2019)
The many functions of ESCRTs
Nat Rev Mol Cell Biol, 21 (1), 25-42
DOI 10.1038/s41580-019-0177-4, PubMed 31705132

Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
ESCRT-mediated phagophore sealing during mitophagy
Autophagy, 16 (5), 826-841
DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

Malerød L, Le Borgne R, Lie-Jensen A, Eikenes ÅH, Brech A, Liestøl K, Stenmark H, Haglund K (2018)
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227

Mejlvang J, Olsvik H, Svenning S, Bruun JA, Abudu YP, Larsen KB, Brech A, Hansen TE, Brenne H, Hansen T, Stenmark H, Johansen T (2018)
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
J Cell Biol, 217 (10), 3640-3655
DOI 10.1083/jcb.201711002, PubMed 30018090

Olsvik HL, Svenning S, Abudu YP, Brech A, Stenmark H, Johansen T, Mejlvang J (2018)
Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
Autophagy, 15 (1), 182-183
DOI 10.1080/15548627.2018.1532265, PubMed 30295124

Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966

Radulovic M, Stenmark H (2018)
ESCRTs in membrane sealing
Biochem Soc Trans, 46 (4), 773-778
DOI 10.1042/BST20170435, PubMed 29903934

Vietri M, Stenmark H (2018)
Orchestrating Nuclear Envelope Sealing during Mitosis
Dev Cell, 47 (5), 541-542
DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298

Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nähse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat Commun, 9 (1), 2932
DOI 10.1038/s41467-018-05345-8, PubMed 30050131

Publications 2017

Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
DOI 10.1083/jcb.201611073, PubMed 29030394

Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876

O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol, 19 (12), 1412-1423
DOI 10.1038/ncb3631, PubMed 29084199

Raiborg C, Schink KO, Stenmark H (2017)
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
DOI 10.15252/embj.201797469, PubMed 28623241

Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
PLoS One, 12 (1), e0170508
DOI 10.1371/journal.pone.0170508, PubMed 28107521

Publications 2016

Campsteijn C, Vietri M, Stenmark H (2016)
Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol, 41, 1-8
DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044

Christ L, Raiborg C, Wenzel EM, Campsteijn C, Stenmark H (2016)
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649

Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H (2016)
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
DOI 10.1083/jcb.201507009, PubMed 26929449

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 12 (1), 1-222
DOI 10.1080/15548627.2015.1100356, PubMed 26799652

Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
Sci Signal, 9 (411), ra8
DOI 10.1126/scisignal.aad0848, PubMed 26787452

Nähse V, Christ L, Stenmark H, Campsteijn C (2016)
The Abscission Checkpoint: Making It to the Final Cut
Trends Cell Biol, 27 (1), 1-11
DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282

Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
PLoS One, 11 (8), e0160507
DOI 10.1371/journal.pone.0160507, PubMed 27482906

Raiborg C, Stenmark H (2016)
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
DOI 10.1083/jcb.201606006, PubMed 27325788

Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
Phosphoinositides in membrane contact sites
Biochem Soc Trans, 44 (2), 425-30
DOI 10.1042/BST20150190, PubMed 27068950

Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans, 44 (2), 441-6
DOI 10.1042/BST20150246, PubMed 27068952

Schink KO, Tan KW, Stenmark H (2016)
Phosphoinositides in Control of Membrane Dynamics
Annu Rev Cell Dev Biol, 32, 143-171
DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122

Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L (2016)
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
Cell Cycle, 15 (5), 628-43
DOI 10.1080/15384101.2016.1146834, PubMed 27104745

Vietri M, Stenmark H, Campsteijn C (2016)
Closing a gap in the nuclear envelope
Curr Opin Cell Biol, 40, 90-97
DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712

Publications 2015

Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
Autophagy, 11 (9), 1458-70
DOI 10.1080/15548627.2015.1067359, PubMed 26207339

Eikenes ÅH, Malerød L, Christensen AL, Steen CB, Mathieu J, Nezis IP, Liestøl K, Huynh JR, Stenmark H, Haglund K (2015)
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
PLoS Genet, 11 (1), e1004904
DOI 10.1371/journal.pgen.1004904, PubMed 25635693

Eikenes ÅH, Malerød L, Lie-Jensen A, Sem Wegner C, Brech A, Liestøl K, Stenmark H, Haglund K (2015)
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
Development, 142 (23), 4107-18
DOI 10.1242/dev.124370, PubMed 26628094

Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-8
DOI 10.1038/nature14359, PubMed 25855459

Raiborg C, Wenzel EM, Stenmark H (2015)
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
DOI 10.15252/embj.201591481, PubMed 26041457

Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443

Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H (2015)
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
DOI 10.1038/nature14408, PubMed 26040712

Zhen Y, Stenmark H (2015)
Cellular functions of Rab GTPases at a glance
J Cell Sci, 128 (17), 3171-6
DOI 10.1242/jcs.166074, PubMed 26272922

Publications 2014

Kostaras E, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2014)
SARA and RNF11 at the crossroads of EGFR signaling and trafficking
Methods Enzymol, 535, 225-47
DOI 10.1016/B978-0-12-397925-4.00014-6, PubMed 24377927

Morelli E, Ginefra P, Mastrodonato V, Beznoussenko GV, Rusten TE, Bilder D, Stenmark H, Mironov AA, Vaccari T (2014)
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila
Autophagy, 10 (12), 2251-68
DOI 10.4161/15548627.2014.981913, PubMed 25551675

Oeste CL, Pinar M, Schink KO, Martínez-Turrión J, Stenmark H, Peñalva MA, Pérez-Sala D (2014)
An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species
PLoS One, 9 (9), e107190
DOI 10.1371/journal.pone.0107190, PubMed 25207810

Raiborg C, Stenmark H (2014)
An ER clamp for endosome fission
EMBO J, 34 (2), 136-7
DOI 10.15252/embj.201490707, PubMed 25502456

Reidick C, El Magraoui F, Meyer HE, Stenmark H, Platta HW (2014)
Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
Cancers (Basel), 7 (1), 1-29
DOI 10.3390/cancers7010001, PubMed 25545884

Sagona AP, Nezis IP, Stenmark H (2014)
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
DOI 10.1155/2014/974393, PubMed 24741567

Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
DOI 10.1016/j.abb.2014.01.006, PubMed 24440309

Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
DOI 10.1038/ncb2959, PubMed 24814515

Wegner CS, Schink KO, Stenmark H, Brech A (2014)
Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
Methods Enzymol, 534, 3-23
DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945

Publications 2013

Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-26
DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040

Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247

Henne WM, Stenmark H, Emr SD (2013)
Molecular mechanisms of the membrane sculpting ESCRT pathway
Cold Spring Harb Perspect Biol, 5 (9)
DOI 10.1101/cshperspect.a016766, PubMed 24003212

Hämälistö S, Pouwels J, de Franceschi N, Saari M, Ivarsson Y, Zimmermann P, Brech A, Stenmark H, Ivaska J (2013)
A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin
PLoS One, 8 (8), e70696
DOI 10.1371/journal.pone.0070696, PubMed 23967087

Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Autophagy, 9 (12), 1955-64
DOI 10.4161/auto.26085, PubMed 24128730

Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
DOI 10.1083/jcb.201205129, PubMed 23878278

O Farrell F, Rusten TE, Stenmark H (2013)
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
FEBS J, 280 (24), 6322-37
DOI 10.1111/febs.12486, PubMed 23953235

Raiborg C, Schink KO, Stenmark H (2013)
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J, 280 (12), 2730-42
DOI 10.1111/febs.12116, PubMed 23289851

Schink KO, Raiborg C, Stenmark H (2013)
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
DOI 10.1002/bies.201300064, PubMed 23881848

Publications 2012

Abrahamsen H, Stenmark H, Platta HW (2012)
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
FEBS Lett, 586 (11), 1584-91
DOI 10.1016/j.febslet.2012.04.046, PubMed 22673570

Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
DOI 10.4161/auto.19496, PubMed 22966490

Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2012)
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking
Oncogene, 32 (44), 5220-32
DOI 10.1038/onc.2012.554, PubMed 23222715

Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
EMBO Rep, 14 (1), 10-1
DOI 10.1038/embor.2012.188, PubMed 23229585

Lobert VH, Stenmark H (2012)
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
DOI 10.1242/jcs.088310, PubMed 22266905

Nezis IP, Stenmark H (2012)
p62 at the interface of autophagy, oxidative stress signaling, and cancer
Antioxid Redox Signal, 17 (5), 786-93
DOI 10.1089/ars.2011.4394, PubMed 22074114

Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
DOI 10.1038/embor.2012.183, PubMed 23154468

Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767

Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
DOI 10.1042/BJ20111424, PubMed 21936852

Stenmark H (2012)
The Rabs: a family at the root of metazoan evolution
BMC Biol, 10, 68
DOI 10.1186/1741-7007-10-68, PubMed 22873178

Publications 2011

Abrahamsen H, Stenmark H (2011)
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
DOI 10.1126/science.1214355, PubMed 22053037

Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
DOI 10.4161/cib.4.1.13550, PubMed 21509167

Hurley JH, Stenmark H (2011)
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
DOI 10.1146/annurev-biophys-042910-155404, PubMed 21332354

Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
DOI 10.1038/onc.2011.109, PubMed 21499309

Lobert VH, Stenmark H (2011)
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
DOI 10.1152/physiol.00054.2010, PubMed 21670163

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451

Platta HW, Stenmark H (2011)
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
DOI 10.1016/j.ceb.2011.03.008, PubMed 21474295

Raiborg C, Stenmark H (2011)
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
DOI 10.1126/science.1204208, PubMed 21436431

Rusten TE, Vaccari T, Stenmark H (2011)
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
DOI 10.1038/ncb2381, PubMed 22193162

Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500

Schink KO, Stenmark H (2011)
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
DOI 10.1016/j.cub.2011.10.035, PubMed 22153165

Stenmark H (2011)
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
DOI 10.1083/jcb.1924pi, PubMed 21339328

Wegner CS, Rodahl LM, Stenmark H (2011)
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
DOI 10.1111/j.1600-0854.2011.01210.x, PubMed 21518165

Publications 2010

Abrahamsen H, Stenmark H (2010)
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
DOI 10.1016/j.cub.2010.03.011, PubMed 20462486

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
DOI 10.4161/auto.6.3.11226, PubMed 20168092

Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
DOI 10.1016/j.cub.2010.03.068, PubMed 20451383

Hansson EM, Lanner F, Das D, Mutvei A, Marklund U, Ericson J, Farnebo F, Stumm G, Stenmark H, Andersson ER, Lendahl U (2010)
Control of Notch-ligand endocytosis by ligand-receptor interaction
J Cell Sci, 123 (Pt 17), 2931-42
DOI 10.1242/jcs.073239, PubMed 20720151

Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442

Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
DOI 10.4161/auto.6.7.13033, PubMed 20724836

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357

Lobert VH, Stenmark H (2010)
Ubiquitination of α-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
DOI 10.4161/cib.3.6.13176, PubMed 21331246

Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
DOI 10.4161/auto.6.8.13694, PubMed 20935512

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-+
DOI 10.4161/auto.6.8.13694

Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
DOI 10.1083/jcb.201002035, PubMed 20713604

Roxrud I, Stenmark H, Malerød L (2010)
ESCRT & Co
Biol Cell, 102 (5), 293-318
DOI 10.1042/BC20090161, PubMed 20222872

Rusten TE, Stenmark H (2010)
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
DOI 10.1038/ncb0310-207, PubMed 20190829

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128
DOI 10.1016/j.febslet.2010.08.016

Stenmark H (2010)
The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
FEBS J, 277 (23), 4837-48
DOI 10.1111/j.1742-4658.2010.07900.x, PubMed 20977678

Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
DOI 10.1369/jhc.2010.955815, PubMed 20713985

Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123

Publications 2009

Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
DOI 10.1242/jcs.053801, PubMed 19808888

Malerød L, Stenmark H (2009)
ESCRTing membrane deformation
Cell, 136 (1), 15-7
DOI 10.1016/j.cell.2008.12.029, PubMed 19135881

Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
DOI 10.4161/auto.5.3.7454, PubMed 19066465

Raiborg C, Stenmark H (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
DOI 10.1038/nature07961, PubMed 19325624

Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
DOI 10.1371/journal.pone.0004354, PubMed 19194501

Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
DOI 10.1042/BST0370137, PubMed 19143618

Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
DOI 10.1016/j.yexcr.2009.07.012, PubMed 19619532

Rusten TE, Stenmark H (2009)
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
DOI 10.1242/jcs.050021, PubMed 19535733

Stenmark H (2009)
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
DOI 10.1038/nrm2728, PubMed 19603039

Stenmark H (2009)
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
DOI 10.1038/nrm2747, PubMed 19702012

Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536

Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
DOI 10.1242/jcs.046391, PubMed 19571114

Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
DOI 10.1007/s00418-009-0643-8, PubMed 19830447

Publications 2008

Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
DOI 10.1038/sj.embor.7401152, PubMed 18188183

Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287

Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
DOI 10.4161/auto.5829, PubMed 18326940

Miaczynska M, Stenmark H (2008)
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
DOI 10.1083/jcb.200711073, PubMed 18195098

Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
DOI 10.1091/mbc.e08-07-0716, PubMed 18685079

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
DOI 10.1083/jcb.200711108, PubMed 18347073

Raposo G, Stenmark H (2008)
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H (2008)
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
DOI 10.1083/jcb.200708115, PubMed 18362181

Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236
DOI 10.4161/auto.5396

Simonsen A, Stenmark H (2008)
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
DOI 10.1083/jcb.200807061, PubMed 18725534

Stuffers S, Brech A, Stenmark H (2008)
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
DOI 10.1016/j.yexcr.2008.10.013, PubMed 19013455

Umebayashi K, Stenmark H, Yoshimori T (2008)
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
DOI 10.1091/mbc.e07-10-0988, PubMed 18508924

Publications 2007

Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
DOI 10.1016/j.biochi.2006.12.012, PubMed 17335953

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
DOI 10.1083/jcb.200702115, PubMed 17984323

Haglund K, Rusten TE, Stenmark H (2007)
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217

Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y et al. (2007)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
DOI 10.4161/auto.5338, PubMed 18188003

Malerød L, Stenmark H (2007)
ESCRTs
Curr Biol, 17 (2), R42-3
DOI 10.1016/j.cub.2006.12.009, PubMed 17240322

Malerød L, Stuffers S, Brech A, Stenmark H (2007)
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
DOI 10.1111/j.1600-0854.2007.00630.x, PubMed 17714434

Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
DOI 10.1242/jcs.017301, PubMed 17959629

Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739

Rusten TE, Stenmark H (2007)
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
DOI 10.1038/445497a, PubMed 17268460

Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
DOI 10.1016/j.cub.2007.09.032, PubMed 17935992

Simonsen A, Stenmark H (2007)
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
DOI 10.1038/nchembio0607-304, PubMed 17510644

Publications 2006

Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
DOI 10.1091/mbc.e05-10-0915, PubMed 16554368

Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
DOI 10.1016/j.gene.2005.11.009, PubMed 16448788

Haglund K, Stenmark H (2006)
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
DOI 10.1038/ncb1106-1218, PubMed 17077855

Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
DOI 10.1038/nsmb1051, PubMed 16462748

Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
DOI 10.1038/nsmb1163, PubMed 17057714

Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
DOI 10.1038/ncb1354, PubMed 16429130

Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
DOI 10.1038/sj.emboj.7600991, PubMed 16467847

Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212

Lindmo K, Stenmark H (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
DOI 10.1242/jcs.02855, PubMed 16467569

Lindmo K, Stenmark H (2006)
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
DOI 10.4161/auto.3091, PubMed 16874068

Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
DOI 10.1016/j.yexcr.2006.06.004, PubMed 16859684

Raiborg C, Slagsvold T, Stenmark H (2006)
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703

Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
DOI 10.1242/jcs.02978, PubMed 16720641

Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
DOI 10.1091/mbc.e06-03-0239, PubMed 16837550

Rusten TE, Stenmark H (2006)
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
DOI 10.1038/nmeth867, PubMed 16554828

Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
DOI 10.1242/jcs.03153, PubMed 16954148

Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
DOI 10.1038/sj.emboj.7601267, PubMed 16888620

Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591

Publications 2005

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
DOI 10.1083/jcb.200507002, PubMed 16286508

Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
DOI 10.1242/jcs.02382, PubMed 15914539

Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
DOI 10.1016/j.cell.2005.02.017, PubMed 15882625

Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330

Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
DOI 10.1074/jbc.M501510200, PubMed 15755741

Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
DOI 10.1016/j.ejcb.2004.12.029, PubMed 16032929

Publications 2004

Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
DOI 10.1091/mbc.e04-03-0250, PubMed 15240819

Bache KG, Slagsvold T, Stenmark H (2004)
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
DOI 10.1038/sj.emboj.7600292, PubMed 15229652

Birkeland HC, Stenmark H (2004)
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215

Gruenberg J, Stenmark H (2004)
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
DOI 10.1038/nrm1360, PubMed 15071556

Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715

Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
DOI 10.1083/jcb.200312018, PubMed 15007060

Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
DOI 10.1242/jcs.01287, PubMed 15292400

Slagsvold T, Stenmark H (2004)
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831

Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
DOI 10.1091/mbc.e04-01-0041, PubMed 15194809

Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
DOI 10.1128/MCB.24.10.4593-4604.2004, PubMed 15121875

Publications 2003

Bache KG, Brech A, Mehlum A, Stenmark H (2003)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
DOI 10.1083/jcb.200302131, PubMed 12900395

Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
DOI 10.1074/jbc.M210843200, PubMed 12551915

Gillooly DJ, Raiborg C, Stenmark H (2003)
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
DOI 10.1007/s00418-003-0591-7, PubMed 14618335

González-Gaitán M, Stenmark H (2003)
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
DOI 10.1016/s0092-8674(03)00932-2, PubMed 14651844

Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
DOI 10.1016/s1534-5807(03)00321-6, PubMed 14602072

Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
DOI 10.1074/jbc.M309653200, PubMed 14604990

Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
DOI 10.1083/jcb.200303018, PubMed 12975344

Raiborg C, Rusten TE, Stenmark H (2003)
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785

Publications 2002

Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964

Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
DOI 10.1242/jcs.115.5.899, PubMed 11870209

Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
DOI 10.1034/j.1600-0854.2002.30605.x, PubMed 12010460

Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
DOI 10.1074/jbc.M107983200, PubMed 11877415

Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
DOI 10.1038/ncb791, PubMed 11988743

Raiborg C, Stenmark H (2002)
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
DOI 10.1247/csf.27.403, PubMed 12576633

Stenmark H, Aasland R, Driscoll PC (2002)
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
DOI 10.1016/s0014-5793(01)03308-7, PubMed 11911884

Publications 2001

Gillooly DJ, Simonsen A, Stenmark H (2001)
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
DOI 10.1042/0264-6021:3550249, PubMed 11284710

Gillooly DJ, Simonsen A, Stenmark H (2001)
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
DOI 10.1083/jcb.200109001, PubMed 11581282

Gillooly DJ, Stenmark H (2001)
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
DOI 10.1126/science.291.5506.993, PubMed 11232585

Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
DOI 10.1105/tpc.13.2.287, PubMed 11226186

Pattni K, Jepson M, Stenmark H, Banting G (2001)
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
DOI 10.1016/s0960-9822(01)00486-9, PubMed 11676927

Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
DOI 10.1093/emboj/20.17.5008, PubMed 11532964

Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
DOI 10.1042/bst0290472, PubMed 11498011

Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
DOI 10.1242/jcs.114.12.2255, PubMed 11493665

Simonsen A, Stenmark H (2001)
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
DOI 10.1038/35087112, PubMed 11483972

Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456

Stenmark H (2001)
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
DOI 10.1006/scdb.2000.0230, PubMed 11292379

Stenmark H, Gillooly DJ (2001)
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
DOI 10.1006/scdb.2000.0236, PubMed 11292385

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
DOI 10.1186/gb-2001-2-5-reviews3007, PubMed 11387043

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol., 2 (5), 3007.1

Publications 2000

Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
DOI 10.1242/jcs.113.19.3531, PubMed 10984443

Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
DOI 10.1074/jbc.M906554199, PubMed 10807926

Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
DOI 10.1093/emboj/19.17.4577, PubMed 10970851

Stenmark H (2000)
Cycling lipids
Curr Biol, 10 (2), R57-9
DOI 10.1016/s0960-9822(00)00279-7, PubMed 10662657

Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
DOI 10.1128/MCB.20.20.7685-7692.2000, PubMed 11003664

Publications 1999

Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999)
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
DOI 10.1046/j.1432-1327.1999.00743.x, PubMed 10491193

Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2) (Pt 2), 539-43
DOI 10.1042/0264-6021:3380539, PubMed 10024533

Corvera S, D'Arrigo A, Stenmark H (1999)
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
DOI 10.1016/S0955-0674(99)80066-0, PubMed 10449332

Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
DOI 10.1042/bst0270666, PubMed 10917663

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
DOI 10.1016/s0009-3084(99)00021-3, PubMed 10358931

Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
DOI 10.1074/jbc.274.41.28857, PubMed 10506127

Stenmark H, Aasland R (1999)
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
DOI 10.1242/jcs.112.23.4175, PubMed 10564636

Publications 1998

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
DOI 10.1038/28767, PubMed 9697764

Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1998)
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
DOI 10.1093/emboj/17.7.1930, PubMed 9524116

Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1) (Pt 1), 213-22
DOI 10.1042/bj3360213, PubMed 9806903

Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053

Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
DOI 10.1038/28879, PubMed 9697774

Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1998)
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
DOI 10.1093/emboj/17.7.1941, PubMed 9524117

Waite RL, Sentry JW, Stenmark H, Toh BH (1998)
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
DOI 10.1006/clin.1997.4455, PubMed 9434799

Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1998)
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
DOI 10.1083/jcb.140.5.1039, PubMed 9490718

Publications 1997

D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016

Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
DOI 10.1016/s0092-8674(00)80380-3, PubMed 9323142

Olkkonen VM, Stenmark H (1997)
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
DOI 10.1016/s0074-7696(08)61608-3, PubMed 9394917

Publications 1996

Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
DOI 10.1074/jbc.271.39.24048, PubMed 8798641

Publications 1995

Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
DOI 10.1074/jbc.270.22.13503, PubMed 7768953

Singer-Krüger B, Stenmark H, Zerial M (1995)
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
DOI 10.1242/jcs.108.11.3509, PubMed 8586662

Stenmark H, Bucci C, Zerial M (1995)
Expression of Rab GTPases using recombinant vaccinia viruses
Methods Enzymol, 257, 155-64
DOI 10.1016/s0076-6879(95)57021-7, PubMed 8583918

Stenmark H, Vitale G, Ullrich O, Zerial M (1995)
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
DOI 10.1016/0092-8674(95)90120-5, PubMed 8521472

Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
DOI 10.1101/sqb.1995.060.01.024, PubMed 8824393

Publications 1994

de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
DOI 10.1016/0896-6273(94)90456-1, PubMed 8043272

Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
DOI 10.1083/jcb.125.2.283, PubMed 8163546

Stenmark H, Parton RG, Steele-Mortimer O, Lütcke A, Gruenberg J, Zerial M (1994)
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
EMBO J, 13 (6), 1287-96
DOI 10.1002/j.1460-2075.1994.tb06381.x, PubMed 8137813

Stenmark H, Valencia A, Martinez O, Ullrich O, Goud B, Zerial M (1994)
Distinct structural elements of rab5 define its functional specificity
EMBO J, 13 (3), 575-83
DOI 10.1002/j.1460-2075.1994.tb06295.x, PubMed 8313902

Publications 1993

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
DOI 10.1021/bi00052a012, PubMed 8418864

Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690

Zerial M, Stenmark H (1993)
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
DOI 10.1016/0955-0674(93)90130-i, PubMed 8257602

Publications 1992

Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
DOI 10.1128/iai.60.8.3296-3302.1992, PubMed 1639497

Madshus IH, Stenmark H (1992)
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
DOI 10.1007/978-3-642-76966-5_1, PubMed 1378368

Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3) (Pt 3), 619-25
DOI 10.1042/bj2810619, PubMed 1536643

Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382

Publications 1991

Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632

Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012

Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
DOI 10.1083/jcb.113.5.1025, PubMed 2040642

Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374

Publications 1990

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980

Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341

Publications 1989

McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631

Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882

OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751

Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538

Publications 1988

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713

Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666

Publications 1985

Kleven A, Stenmark H (1985)
Inneholder urin fra astmatikere histaninfrisettende substanser?: Utvikling av biologisk testmetode og testing av peptidlignende materiale fra testurin
A. Kleven & H. Stenmark, Oslo, 126 s.
BIBSYS 961241098