Jon-Vidar Gaustad
Position: Post doc, Ph.D.
Phone: +47 22 78 12 22
Email:
Education: Dr. philos.
Research interests/projects: Intravital microscopy; Non-invasive detection of tumor hypoxia by DCE-MRI
 

Author network for Jon-Vidar Gaustad by COREMINE medical


Publications 2017

Andersen LMK, Wegner CS, Simonsen TG, Huang R, Gaustad JV, Hauge A, Galappathi K, Rofstad EK (2017)
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget, 8 (29), 48060-48074
PubMed 28624797

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK (2017)
The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Transl Oncol, 10 (2), 158-167
PubMed 28167241

Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2017)
Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BMC Cancer, 17 (1), 411
PubMed 28606060

Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2017)
Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
J Transl Med, 15 (1), 241
PubMed 29183378

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2017)
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
J Transl Med, 15 (1), 225
PubMed 29100521

Wegner CS, Hauge A, Gaustad JV, Andersen LMK, Simonsen TG, Galappathi K, Rofstad EK (2017)
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts
Acta Oncol, 56 (12), 1754-1762
PubMed 28661213

Publications 2016

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK (2016)
Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression
Oncotarget, 7 (47), 76806-76815
PubMed 27756886

Rofstad EK, Huang R, Galappathi K, Andersen LM, Wegner CS, Hauge A, Gaustad JV, Simonsen TG (2016)
Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis
Oncotarget, 7 (35), 56986-56997
PubMed 27486768

Rofstad EK, Simonsen TG, Huang R, Andersen LM, Galappathi K, Ellingsen C, Wegner CS, Hauge A, Gaustad JV (2016)
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix
Cancer Lett, 373 (2), 147-55
PubMed 26828134

Simonsen TG, Gaustad JV, Rofstad EK (2016)
Intracranial Tumor Cell Migration and the Development of Multiple Brain Metastases in Malignant Melanoma
Transl Oncol, 9 (3), 211-8
PubMed 27267839

Wegner CS, Gaustad JV, Andersen LM, Simonsen TG, Rofstad EK (2016)
Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content
J Transl Med, 14 (1), 161
PubMed 27268062

Publications 2015

Gaustad JV, Simonsen TG, Smistad R, Wegner CS, Andersen LM, Rofstad EK (2015)
Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging
BMC Cancer, 15, 900
PubMed 26573613

Simonsen TG, Gaustad JV, Rofstad EK (2015)
Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases
J Exp Clin Cancer Res, 34, 150
PubMed 26667022

Publications 2014

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK (2014)
Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts
Microvasc Res, 98, 159-65
PubMed 24555949

Publications 2013

Gaustad JV, Pozdniakova V, Hompland T, Simonsen TG, Rofstad EK (2013)
Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts
J Exp Clin Cancer Res, 32, 93
PubMed 24245934

Publications 2012

Gaustad JV, Simonsen TG, Leinaas MN, Rofstad EK (2012)
Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts
BMC Cancer, 12, 388
PubMed 22947392

Gaustad JV, Simonsen TG, Leinaas MN, Rofstad EK (2012)
A novel application of dorsal window chambers: repetitive imaging of tumor-associated lymphatics
Microvasc Res, 83 (3), 360-5
PubMed 22342351

Gaustad JV, Simonsen TG, Roa AM, Rofstad EK (2012)
Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply
Microvasc Res, 85, 10-5
PubMed 23154277

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK (2012)
High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts
PLoS One, 7 (6), e40006
PubMed 22768196

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK (2012)
Vascular abnormalities associated with acute hypoxia in human melanoma xenografts
Radiother Oncol, 105 (1), 72-8
PubMed 23022175

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK (2012)
Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts
Microvasc Res, 85, 16-23
PubMed 23149341

Publications 2011

Egeland TA, Gulliksrud K, Gaustad JV, Mathiesen B, Rofstad EK (2011)
Dynamic contrast-enhanced-MRI of tumor hypoxia
Magn Reson Med, 67 (2), 519-30
PubMed 21661044

Publications 2010

Egeland TA, Gaustad JV, Galappathi K, Rofstad EK (2010)
Magnetic resonance imaging of tumor necrosis
Acta Oncol, 50 (3), 427-34
PubMed 20950229

Gulliksrud K, Egeland TAM, Gaustad JV, Rofstad EK (2010)
Interstitial fluid pressure of tumors as a function of parameters derived by dynamic contrast-enhanced magnetic resonance imaging: Response to letter by Farace and Boschi
Radiother. Oncol., 94 (3), 385-386

Rofstad EK, Gaustad JV, Egeland TA, Mathiesen B, Galappathi K (2010)
Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination
Int J Cancer, 127 (7), 1535-46
PubMed 20091868

Simonsen TG, Gaustad JV, Rofstad EK (2010)
Development of hypoxia in a preclinical model of tumor micrometastases
Int J Radiat Oncol Biol Phys, 76 (3), 879-88
PubMed 20159362

Publications 2009

Egeland TA, Simonsen TG, Gaustad JV, Gulliksrud K, Ellingsen C, Rofstad EK (2009)
Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images
Radiat Res, 172 (3), 339-47
PubMed 19708783

Ellingsen C, Egeland TA, Gulliksrud K, Gaustad JV, Mathiesen B, Rofstad EK (2009)
Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 73 (3), 838-45
PubMed 19215820

Ellingsen C, Natvig I, Gaustad JV, Gulliksrud K, Egeland TA, Rofstad EK (2009)
Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors
J Cancer Res Clin Oncol, 135 (9), 1177-84
PubMed 19214568

Gaustad JV, Simonsen TG, Brurberg KG, Huuse EM, Rofstad EK (2009)
Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries
Neoplasia, 11 (3), 277-85
PubMed 19242609

Rofstad EK, Gaustad JV, Brurberg KG, Mathiesen B, Galappathi K, Simonsen TG (2009)
Radiocurability is associated with interstitial fluid pressure in human tumor xenografts
Neoplasia, 11 (11), 1243-51
PubMed 19881960

Publications 2008

Brurberg KG, Gaustad JV, Mollatt CS, Rofstad EK (2008)
Temporal heterogeneity in blood supply in human tumor xenografts
Neoplasia, 10 (7), 727-35
PubMed 18592011

Egeland TA, Gaustad JV, Benjaminsen IC, Hedalen K, Mathiesen B, Rofstad EK (2008)
Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI
Radiat Res, 169 (6), 689-99
PubMed 18494552

Gaustad JV, Brurberg KG, Simonsen TG, Mollatt CS, Rofstad EK (2008)
Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging
Neoplasia, 10 (4), 354-62
PubMed 18392132

Norum OJ, Gaustad JV, Angell-Petersen E, Rofstad EK, Peng Q, Giercksky KE, Berg K (2008)
Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
Photochem Photobiol, 85 (3), 740-9
PubMed 19076314

Publications 2007

Gaustad JV, Benjaminsen IC, Ruud EB, Rofstad EK (2007)
Dynamic contrast-enhanced magnetic resonance imaging of human melanoma xenografts with necrotic regions
J Magn Reson Imaging, 26 (1), 133-43
PubMed 17659570

Vestvik IK, Egeland TA, Gaustad JV, Mathiesen B, Rofstad EK (2007)
Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI
J Magn Reson Imaging, 26 (4), 1033-42
PubMed 17896373

Øye KS, Gulati G, Graff BA, Gaustad JV, Brurberg KG, Rofstad EK (2007)
A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber
Microvasc Res, 75 (2), 179-87
PubMed 17688890

Publications 2006

Egeland TA, Gaustad JV, Vestvik IK, Benjaminsen IC, Mathiesen B, Rofstad EK (2006)
Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI
Magn Reson Med, 55 (4), 874-82
PubMed 16506163

Publications 2005

Gaustad JV, Benjaminsen IC, Graff BA, Brurberg KG, Ruud EB, Rofstad EK (2005)
Intratumor heterogeneity in blood perfusion in orthotopic human melanoma xenografts assessed by dynamic contrast-enhanced magnetic resonance imaging
J Magn Reson Imaging, 21 (6), 792-800
PubMed 15906326