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Publications (original articles or review articles) published in 2017 from OUS - Institute for Cancer Research

185 publications found

Abravan A, Knudtsen IS, Eide HA, Løndalen AM, Helland Å, van Luijk P, Malinen E (2017)
A new method to assess pulmonary changes using (18)F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy
Acta Oncol, 56 (11), 1597-1603
PubMed 28849707

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
PubMed 28067430

Alves CP, Dey-Guha I, Kabraji S, Yeh AC, Talele NP, Solé X, Chowdhury J, Mino-Kenudson M, Loda M, Sgroi D, Borresen-Dale AL, Russnes HG, Ross KN, Ramaswamy S (2017)
AKT1low quiescent cancer cells promote solid tumor growth
Mol Cancer Ther (in press)
PubMed 29054988

Anda S, Zach R, Grallert B (2017)
Activation of Gcn2 in response to different stresses
PLoS One, 12 (8), e0182143
PubMed 28771613

Andersen LMK, Wegner CS, Simonsen TG, Huang R, Gaustad JV, Hauge A, Galappathi K, Rofstad EK (2017)
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget, 8 (29), 48060-48074
PubMed 28624797

Andersson Y, Haavardtun SI, Davidson B, Dørum A, Fleten KG, Fodstad Ø, Flatmark K (2017)
MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
Oncotarget, 8 (37), 61800-61809
PubMed 28977905

Andreassen R, Woldemariam NT, Egeland IØ, Agafonov O, Sindre H, Høyheim B (2017)
Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
BMC Genomics, 18 (1), 349
PubMed 28472924

Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
BMC Cancer, 17 (1), 406
PubMed 28592327

Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
Breast Cancer Res, 19 (1), 44
PubMed 28356166

Azizi M, Ghourchian H, Yazdian F, Bagherifam S, Bekhradnia S, Nyström B (2017)
Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
Sci Rep, 7 (1), 5178
PubMed 28701707

Bakke KM, Hole KH, Dueland S, Grøholt KK, Flatmark K, Ree AH, Seierstad T, Redalen KR (2017)
Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival
Acta Oncol, 56 (6), 813-818
PubMed 28464745

Balasiddaiah A, Davanian H, Aleman S, Pasetto A, Frelin L, Sällberg M, Lohmann V, Koh S, Bertoletti A, Chen M (2017)
Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties
J Virol, 91 (9)
PubMed 28228595

Barfeld SJ, Urbanucci A, Itkonen HM, Fazli L, Hicks JL, Thiede B, Rennie PS, Yegnasubramanian S, DeMarzo AM, Mills IG (2017)
c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks
EBioMedicine, 18, 83-93
PubMed 28412251

Behjati S, Tarpey PS, Haase K, Ye H, Young MD, Alexandrov LB, Farndon SJ, Collord G, Wedge DC, Martincorena I, Cooke SL, Davies H, Mifsud W, Lidgren M, Martin S, Latimer C, Maddison M, Butler AP, Teague JW, Pillay N, Shlien A, McDermott U, Futreal PA, Baumhoer D, Zaikova O et al. (2017)
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
Nat Commun, 8, 15936
PubMed 28643781

Berg KCG, Eide PW, Eilertsen IA, Johannessen B, Bruun J, Danielsen SA, Bjørnslett M, Meza-Zepeda LA, Eknæs M, Lind GE, Myklebost O, Skotheim RI, Sveen A, Lothe RA (2017)
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
Mol Cancer, 16 (1), 116
PubMed 28683746

Bilir B, Sharma NV, Lee J, Hammarstrom B, Svindland A, Kucuk O, Moreno CS (2017)
Effects of genistein supplementation on genome‑wide DNA methylation and gene expression in patients with localized prostate cancer
Int J Oncol, 51 (1), 223-234
PubMed 28560383

Bjørklund SS, Panda A, Kumar S, Seiler M, Robinson D, Gheeya J, Yao M, Alnæs GIG, Toppmeyer D, Riis M, Naume B, Børresen-Dale AL, Kristensen VN, Ganesan S, Bhanot G (2017)
Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma
Sci Rep, 7 (1), 5568
PubMed 28717182

Bollum LK, Huse K, Oksvold MP, Bai B, Hilden VI, Forfang L, Yoon SO, Wälchli S, Smeland EB, Myklebust JH (2017)
BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
PLoS One, 12 (5), e0177188
PubMed 28489883

Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland ÅA, Røsok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjørnbeth BA, Vauthey JN (2017)
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann Surg (in press)
PubMed 28549012

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2017)
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer (in press)
PubMed 28972967

Bus MP, Szafranski A, Sellevold S, Goryn T, Jutte PC, Bramer JA, Fiocco M, Streitbürger A, Kotrych D, van de Sande MA, Dijkstra PD (2017)
LUMiC(®) Endoprosthetic Reconstruction After Periacetabular Tumor Resection: Short-term Results
Clin Orthop Relat Res, 475 (3), 686-695
PubMed 27020434

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
Interrogating open issues in cancer precision medicine with patient-derived xenografts
Nat Rev Cancer, 17 (4), 254-268
PubMed 28104906

Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
Sci Total Environ, 610-611, 972-982
PubMed 28838034

Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Loo PV (2017)
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
Nat Commun, 8 (1), 1221
PubMed 29089486

Christie C, Pomeroy A, Nair R, Berg K, Hirschberg H (2017)
Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy
Photodiagnosis Photodyn Ther, 18, 140-148
PubMed 28257943

Chymkowitch P, Enserink JM (2017)
Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
Biochim Biophys Acta (in press)
PubMed 29127063

Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
PubMed 28096404

Chymkowitch P, P AN, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM (2017)
Corrigendum: Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 27 (2), 334
PubMed 28148563

Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
Bioinformatics approaches to profile the tumor microenvironment for immunotherapeutic discovery
Curr Pharm Des (in press)
PubMed 28699527

Cui XY, Skretting G, Tinholt M, Stavik B, Dahm AEA, Sahlberg KK, Kanse S, Iversen N, Sandset PM (2017)
A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in the breast cancer cell line MCF-7
Thromb Res, 157, 111-116
PubMed 28734156

Dannenfelser R, Nome M, Tahiri A, Ursini-Siegel J, Vollan HKM, Haakensen VD, Helland Å, Naume B, Caldas C, Børresen-Dale AL, Kristensen VN, Troyanskaya OG (2017)
Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
Oncotarget, 8 (34), 57121-57133
PubMed 28915659

Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, Ramakrishna M, Martin S, Boyault S, Sieuwerts AM, Simpson PT, King TA, Raine K, Eyfjord JE, Kong G, Borg Å, Birney E, Stunnenberg HG, van de Vijver MJ, Børresen-Dale AL, Martens JW, Span PN, Lakhani SR, Vincent-Salomon A, Sotiriou C et al. (2017)
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
Nat Med, 23 (4), 517-525
PubMed 28288110

Davies H, Morganella S, Purdie CA, Jang SJ, Borgen E, Russnes H, Glodzik D, Zou X, Viari A, Richardson AL, Børresen-Dale AL, Thompson A, Eyfjord JE, Kong G, Stratton MR, Nik-Zainal S (2017)
Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency
Cancer Res, 77 (18), 4755-4762
PubMed 28904067

Dienstmann R, Mason MJ, Sinicrope FA, Phipps AI, Tejpar S, Nesbakken A, Danielsen SA, Sveen A, Buchanan DD, Clendenning M, Rosty C, Bot B, Alberts SR, Milburn Jessup J, Lothe RA, Delorenzi M, Newcomb PA, Sargent D, Guinney J (2017)
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
Ann Oncol, 28 (5), 1023-1031
PubMed 28453697

Domanska D, Vodák D, Lund-Andersen C, Salvatore S, Hovig E, Sandve GK (2017)
The rainfall plot: its motivation, characteristics and pitfalls
BMC Bioinformatics, 18 (1), 264
PubMed 28521741

Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2017)
Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
Fam Cancer (in press)
PubMed 28608266

Dukic AR, Haugen LH, Pidoux G, Leithe E, Bakke O, Taskén K (2017)
A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells
Cell Signal, 32, 1-11
PubMed 28077322

Dumeaux V, Fjukstad B, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Børresen-Dale AL, Bongo LA, Lund E, Hallett M (2017)
Interactions between the tumor and the blood systemic response of breast cancer patients
PLoS Comput Biol, 13 (9), e1005680
PubMed 28957325

Egeland EV, Boye K, Park D, Synnestvedt M, Sauer T, Oslo Breast Cancer Consortium (OSBREAC), Naume B, Borgen E, Mælandsmo GM (2017)
Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer
Breast Cancer Res Treat, 162 (1), 127-137
PubMed 28058579

Egger B, Bachmann L, Fromm B (2017)
Atp8 is in the ground pattern of flatworm mitochondrial genomes
BMC Genomics, 18 (1), 414
PubMed 28549457

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res (in press)
PubMed 29098521

Ellingjord-Dale M, Vos L, Hjerkind KV, Hjartåker A, Russnes HG, Tretli S, Hofvind S, Dos-Santos-Silva I, Ursin G (2017)
Alcohol, physical activity, smoking and breast cancer subtypes in a large nested case-control study from the Norwegian Breast Cancer Screening Program
Cancer Epidemiol Biomarkers Prev (in press)
PubMed 28877889

Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
BMC Cancer, 17 (1), 730
PubMed 29121858

Engkvist ME, Stratford EW, Lorenz S, Meza-Zepeda LA, Myklebost O, Munthe E (2017)
Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b
Sci Rep, 7 (1), 9655
PubMed 28848235

Enserink JM (2017)
Regulation of Cellular Processes by SUMO: Understudied Topics
Adv Exp Med Biol, 963, 89-97
PubMed 28197907

Euceda LR, Haukaas TH, Giskeodegard GF, Vettukattil R, Engel J, Silwal-Pandit L, Lundgren S, Borgen E, Garred O, Postma G, Buydens LMC, Borresen-Dale AL, Engebraaten O, Bathen TF (2017)
Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
Metabolomics, 13 (4), 37

Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN (2017)
DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
Oncotarget, 8 (1), 1074-1082
PubMed 27911866

Fleischer T, Tekpli X, Mathelier A, Wang S, Nebdal D, Dhakal HP, Sahlberg KK, Schlichting E, Oslo Breast Cancer Research Consortium (OSBREAC), Børresen-Dale AL, Borgen E, Naume B, Eskeland R, Frigessi A, Tost J, Hurtado A, Kristensen VN (2017)
DNA methylation at enhancers identifies distinct breast cancer lineages
Nat Commun, 8 (1), 1379
PubMed 29123100

Flem-Karlsen K, Tekle C, Andersson Y, Flatmark K, Fodstad Ø, Nunes-Xavier CE (2017)
Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
Pigment Cell Melanoma Res, 30 (5), 467-476
PubMed 28513992

Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
J Bacteriol, 199 (24)
PubMed 28947673

Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Biochim Biophys Acta, 1864 (12), 2241-2252
PubMed 28867611

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B, Oslo-CoMet study group (2017)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg (in press)
PubMed 28657937

Fromm B, Ovchinnikov V, Høye E, Bernal D, Hackenberg M, Marcilla A (2017)
On the presence and immunoregulatory functions of extracellular microRNAs in the trematode Fasciola hepatica
Parasite Immunol, 39 (2)
PubMed 27809346

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2017)
Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
Ann Surg Oncol, 24 (7), 1916-1922
PubMed 28224367

Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2017)
MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
BMC Cancer, 17 (1), 97
PubMed 28158999

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK (2017)
The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Transl Oncol, 10 (2), 158-167
PubMed 28167241

Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2017)
Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BMC Cancer, 17 (1), 411
PubMed 28606060

Gaware VS, Håkerud M, Juzeniene A, Høgset A, Berg K, Másson M (2017)
Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization
Biomacromolecules, 18 (4), 1108-1126
PubMed 28245649

Gederaas OA, Johnsson A, Berg K, Manandhar R, Shrestha C, Skåre D, Ekroll IK, Høgset A, Hjelde A (2017)
Photochemical internalization in bladder cancer - development of an orthotopic in vivo model
Photochem Photobiol Sci, 16 (11), 1664-1676
PubMed 28972608

Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K et al. (2017)
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition
Cancer Discov, 7 (10), 1098-1115
PubMed 28652380

Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Viari A et al. (2017)
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
Nat Genet, 49 (3), 341-348
PubMed 28112740

Graudenzi A, Cava C, Bertoli G, Fromm B, Flatmark K, Mauri G, Castiglioni I (2017)
Pathway-based classification of breast cancer subtypes
Front Biosci (Landmark Ed), 22, 1697-1712
PubMed 28410140

Graudenzi A, Cava C, Bertoli G, Fromm B, Flatmark K, Mauri G, Castiglioni I (2017)
Pathway-based classification of breast cancer subtypes
Front. Biosci., 22, 1697-1712

Guren TK, Thomsen M, Kure EH, Sorbye H, Glimelius B, Pfeiffer P, Österlund P, Sigurdsson F, Lothe IMB, Dalsgaard AM, Skovlund E, Christoffersen T, Tveit KM (2017)
Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study
Br J Cancer, 116 (10), 1271-1278
PubMed 28399112

Halldorsson S, Rohatgi N, Magnusdottir M, Choudhary KS, Gudjonsson T, Knutsen E, Barkovskaya A, Hilmarsdottir B, Perander M, Mælandsmo GM, Gudmundsson S, Rolfsson Ó (2017)
Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition
Cancer Lett, 396, 117-129
PubMed 28323032

Halvorsen AR, Kristensen G, Embleton A, Adusei C, Barretina-Ginesta MP, Beale P, Helland Å (2017)
Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients
Dis Markers, 2017, 3098542
PubMed 28293063

Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
ChemMedChem, 12 (8), 613-620
PubMed 28334511

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2017)
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
J Transl Med, 15 (1), 225
PubMed 29100521

Hauge S, Naucke C, Hasvold G, Joel M, Rødland GE, Juzenas P, Stokke T, Syljuåsen RG (2017)
Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading
Oncotarget, 8 (7), 10966-10979
PubMed 28030798

Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
Int J Cancer, 141 (1), 184-190
PubMed 28387924

Hessvik NP, Llorente A (2017)
Current knowledge on exosome biogenesis and release
Cell Mol Life Sci (in press)
PubMed 28733901

Hilmarsdottir B, Briem E, Halldorsson S, Kricker J, Ingthorsson S, Gustafsdottir S, Mælandsmo GM, Magnusson MK, Gudjonsson T (2017)
Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells
Cell Death Dis, 8 (5), e2769
PubMed 28492548

Holm KL, Syljuåsen RG, Hasvold G, Alsøe L, Nilsen H, Ivanauskiene K, Collas P, Shaposhnikov S, Collins A, Indrevær RL, Aukrust P, Fevang B, Blomhoff HK (2017)
TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency
PLoS One, 12 (10), e0185708
PubMed 28973009

Hompland I, Bruland ØS, Hølmebakk T, Poulsen JP, Stoldt S, Hall KS, Boye K (2017)
Prediction of long-term survival in patients with metastatic gastrointestinal stromal tumor: analysis of a large, single-institution cohort
Acta Oncol, 56 (10), 1317-1323
PubMed 28557540

Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol (in press)
PubMed 29030394

Huang R, Andersen LMK, Rofstad EK (2017)
Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
J Transl Med, 15 (1), 203
PubMed 29017512

Huang R, Rofstad EK (2017)
Cancer stem cells (CSCs), cervical CSCs and targeted therapies
Oncotarget, 8 (21), 35351-35367
PubMed 27343550

Inderberg EM, Wälchli S, Myhre MR, Trachsel S, Almåsbak H, Kvalheim G, Gaudernack G (2017)
T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
Oncoimmunology, 6 (4), e1302631
PubMed 28507809

Itkonen HM, Brown M, Urbanucci A, Tredwell G, Ho Lau C, Barfeld S, Hart C, Guldvik IJ, Takhar M, Heemers HV, Erho N, Bloch K, Davicioni E, Derua R, Waelkens E, Mohler JL, Clarke N, Swinnen JV, Keun HC, Rekvig OP, Mills IG (2017)
Lipid degradation promotes prostate cancer cell survival
Oncotarget, 8 (24), 38264-38275
PubMed 28415728

Jernström S, Hongisto V, Leivonen SK, Due EU, Tadele DS, Edgren H, Kallioniemi O, Perälä M, Mælandsmo GM, Sahlberg KK (2017)
Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response
Breast Cancer (Dove Med Press), 9, 185-198
PubMed 28356768

Jha SK, Rauniyar K, Karpanen T, Leppänen VM, Brouillard P, Vikkula M, Alitalo K, Jeltsch M (2017)
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
Sci Rep, 7 (1), 4916
PubMed 28687807

Ju YS, Martincorena I, Gerstung M, Petljak M, Alexandrov LB, Rahbari R, Wedge DC, Davies HR, Ramakrishna M, Fullam A, Martin S, Alder C, Patel N, Gamble S, O'Meara S, Giri DD, Sauer T, Pinder SE, Purdie CA, Borg Å, Stunnenberg H, van de Vijver M, Tan BK, Caldas C, Tutt A et al. (2017)
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
Nature, 543 (7647), 714-718
PubMed 28329761

Kanduri C, Domanska D, Hovig E, Sandve GK (2017)
Genome build information is an essential part of genomic track files
Genome Biol, 18 (1), 175
PubMed 28911336

Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S (2017)
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation
Circ Res, 120 (8), 1263-1275
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Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
PubMed 28077876

Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
Protection against Shiga Toxins
Toxins (Basel), 9 (2)
PubMed 28165371

Khan A, Mathelier A (2017)
Intervene: a tool for intersection and visualization of multiple gene or genomic region sets
BMC Bioinformatics, 18 (1), 287
PubMed 28569135

Kolberg M, Bruun J, Murumägi A, Mpindi JP, Bergsland CH, Høland M, Eilertsen IA, Danielsen SA, Kallioniemi O, Lothe RA (2017)
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
Mol Oncol, 11 (9), 1156-1171
PubMed 28556483

Kristian A, Holtedahl JE, Torheim T, Futsaether C, Hernes E, Engebraaten O, Mælandsmo GM, Malinen E (2017)
Dynamic 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Positron Emission Tomography for Chemotherapy Response Monitoring of Breast Cancer Xenografts
Mol Imaging Biol, 19 (2), 271-279
PubMed 27541026

Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
PLoS One, 12 (7), e0182030
PubMed 28759630

Leithe E, Mesnil M, Aasen T (2017)
The connexin 43 C-terminus: A tail of many tales
Biochim Biophys Acta (in press)
PubMed 28526583

Leroy B, Ballinger ML, Baran-Marszak F, Bond GL, Braithwaite A, Concin N, Donehower LA, El-Deiry WS, Fenaux P, Gaidano G, Langerød A, Hellstrom-Lindberg E, Iggo R, Lehmann-Che J, Mai PL, Malkin D, Moll UM, Myers JN, Nichols KE, Pospisilova S, Ashton-Prolla P, Rossi D, Savage SA, Strong LC, Tonin PN et al. (2017)
Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
Cancer Res, 77 (6), 1250-1260
PubMed 28254861

Li X, Grigalavicius M, Li Y, Li X, Zhong Y, Huang R, Yu D, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
Tumour Biol, 39 (8), 1010428317713671
PubMed 28789597

Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Sci Rep, 7 (1), 5081
PubMed 28698547

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 8 (4), 7208-7213
PubMed 28179591

Lilleby W, Gaudernack G, Brunsvig PF, Vlatkovic L, Schulz M, Mills K, Hole KH, Inderberg EM (2017)
Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer
Cancer Immunol Immunother, 66 (7), 891-901
PubMed 28391357

Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M (2017)
Interplay between Immune Checkpoint Proteins and Cellular Metabolism
Cancer Res, 77 (6), 1245-1249
PubMed 28246276

Lind GE, Guriby M, Ahlquist T, Hussain I, Jeanmougin M, Søreide K, Kørner H, Lothe RA, Nordgård O (2017)
Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
Clin Epigenetics, 9, 97
PubMed 28878843

Liu LL, Béziat V, Oei VYS, Pfefferle A, Schaffer M, Lehmann S, Hellström-Lindberg E, Söderhäll S, Heyman M, Grandér D, Malmberg KJ (2017)
Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells
Cancer Immunol Res, 5 (8), 654-665
PubMed 28637877

Lund KV, Simonsen TG, Kristensen GB, Rofstad EK (2017)
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Acta Oncol, 56 (5), 675-681
PubMed 28447564

Lunde NN, Haugen MH, Bodin Larsen KB, Damgaard I, Pettersen SJ, Kasem R, Rut W, Drag M, Poreba M, Johansen HT, Solberg R (2017)
Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions
Biochimie, 139, 27-37
PubMed 28528272

Lyng H, Malinen E (2017)
Hypoxia in cervical cancer: from biology to imaging
Clin Transl Imaging, 5 (4), 373-388
PubMed 28804704

Lågstad S, Zhao S, Hoff AM, Johannessen B, Lingjærde OC, Skotheim RI (2017)
chimeraviz: a tool for visualizing chimeric RNA
Bioinformatics, 33 (18), 2954-2956
PubMed 28525538

Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Nucleus, 8 (4), 404-420
PubMed 28402725

Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sørensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PØ (2017)
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)
Nucleic Acids Res, 45 (8), 4370-4389
PubMed 28108655

Malmberg KJ, Carlsten M, Björklund A, Sohlberg E, Bryceson YT, Ljunggren HG (2017)
Natural killer cell-mediated immunosurveillance of human cancer
Semin Immunol, 31, 20-29
PubMed 28888619

Malmberg KJ, Sohlberg E, Goodridge JP, Ljunggren HG (2017)
Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition
Immunogenetics, 69 (8-9), 547-556
PubMed 28699110

Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
PLoS One, 12 (1), e0170716
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McGowan M, Kleinberg L, Halvorsen AR, Helland Å, Brustugun OT (2017)
NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
Genes Cancer, 8 (3-4), 497-504
PubMed 28680534

Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
PLoS One, 12 (1), e0169074
PubMed 28045981

Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, Tabernero A, Yamasaki H, Yeh ES, Dagli MLZ, Naus CC (2017)
An update on minding the gap in cancer
Biochim Biophys Acta (in press)
PubMed 28655619

Mezheyeuski A, Strell C, Hrynchyk I, Guren TK, Dragomir A, Doroshenko T, Pashkova O, Gorgun J, Ruksha K, Pfeiffer P, Kure EH, Sorbye H, Edler D, Martling A, Glimelius B, Östman A, Portyanko A (2017)
Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer
Virchows Arch (in press)
PubMed 29134439

Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, French JD, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M et al. (2017)
Association analysis identifies 65 new breast cancer risk loci
Nature, 551 (7678), 92-94
PubMed 29059683

Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, Rostamianfar A, Finucane H, Bolla MK, McGuffog L, Wang Q, Aalfs CM, ABCTB Investigators, Adams M, Adlard J, Agata S, Ahmed S, Ahsan H, Aittomäki K, Al-Ejeh F et al. (2017)
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Nat Genet (in press)
PubMed 29058716

Munkley J, McClurg UL, Livermore KE, Ehrmann I, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Mills IG, Robson CN, Rajan P, Elliott DJ (2017)
The cancer-associated cell migration protein TSPAN1 is under control of androgens and its upregulation increases prostate cancer cell migration
Sci Rep, 7 (1), 5249
PubMed 28701765

Møller P, Hovig E (2017)
Our genes, our selves: hereditary breast cancer and biological citizenship in Norway
Med Health Care Philos (in press)
PubMed 28939999

Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
Gut (in press)
PubMed 28754778

Namløs HM, Zaikova O, Bjerkehagen B, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2017)
Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
BMC Cancer, 17 (1), 29
PubMed 28061772

Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
Oncoimmunology, 6 (8), e1338236
PubMed 28920000

Niemiec MJ, Grumaz C, Ermert D, Desel C, Shankar M, Lopes JP, Mills IG, Stevens P, Sohn K, Urban CF (2017)
Dual transcriptome of the immediate neutrophil and Candida albicans interplay
BMC Genomics, 18 (1), 696
PubMed 28874114

Norum OJ, Fremstedal ASV, Weyergang A, Golab J, Berg K (2017)
Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
J Control Release, 268, 120-127 (in press)
PubMed 29042319

O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol (in press)
PubMed 29084199

Ohnstad HO, Borgen E, Falk RS, Lien TG, Aaserud M, Sveli MAT, Kyte JA, Kristensen VN, Geitvik GA, Schlichting E, Wist EA, Sørlie T, Russnes HG, Naume B (2017)
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
Breast Cancer Res, 19 (1), 120
PubMed 29137653

Olsen CE, Sellevold S, Theodossiou T, Patzke S, Berg K (2017)
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin
Photodiagnosis Photodyn Ther (in press)
PubMed 28838761

Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
PubMed 28784290

Ovchinnikov VY, Mordvinov VA, Fromm B (2017)
Extreme conservation of miRNA complements in opisthorchiids
Parasitol Int, 66 (6), 773-776
PubMed 28916307

Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
A novel community driven software for functional enrichment analysis of extracellular vesicles data
J Extracell Vesicles, 6 (1), 1321455
PubMed 28717418

Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K (2017)
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
Oncotarget, 8 (14), 22606-22615
PubMed 28186983

Quigley DA, Tahiri A, Lüders T, Riis MH, Balmain A, Børresen-Dale AL, Bukholm I, Kristensen V (2017)
Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue
Oncoimmunology, 6 (11), e1356142
PubMed 29147603

Rahman MM, Franch-Marro X, Maestro JL, Martin D, Casali A (2017)
Local Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila
Sci Rep, 7 (1), 11677
PubMed 28916802

Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
ESMO Open, 2 (2), e000158
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Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
BMC Clin Pathol, 17, 6
PubMed 28405177

Rodríguez M, Bajo-Santos C, Hessvik NP, Lorenz S, Fromm B, Berge V, Sandvig K, Linē A, Llorente A (2017)
Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes
Mol Cancer, 16 (1), 156
PubMed 28982366

Rossi BM, Palmero EI, López-Kostner F, Sarroca C, Vaccaro CA, Spirandelli F, Ashton-Prolla P, Rodriguez Y, de Campos Reis Galvão H, Reis RM, Escremim de Paula A, Capochin Romagnolo LG, Alvarez K, Della Valle A, Neffa F, Kalfayan PG, Spirandelli E, Chialina S, Gutiérrez Angulo M, Castro-Mujica MDC, Sanchez de Monte J, Quispe R, da Silva SD, Rossi NT, Barletta-Carrillo C et al. (2017)
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
BMC Cancer, 17 (1), 623
PubMed 28874130

Rothe C, Rødland GE, Anda S, Stonyte V, Boye E, Lopez-Aviles S, Grallert B (2017)
A checkpoint-independent mechanism delays entry into mitosis after UV irradiation
J Cell Sci (in press)
PubMed 29046339

Russnes HG, Lingjærde OC, Børresen-Dale AL, Caldas C (2017)
Breast Cancer Molecular Stratification: From Intrinsic Subtypes to Integrative Clusters
Am J Pathol, 187 (10), 2152-2162
PubMed 28733194

Rustad EH, Coward E, Skytøen ER, Misund K, Holien T, Standal T, Børset M, Beisvag V, Myklebost O, Meza-Zepeda LA, Dai HY, Sundan A, Waage A (2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum
Haematologica, 102 (7), 1266-1272
PubMed 28385781

Saeednejad Zanjani L, Madjd Z, Abolhasani M, Andersson Y, Rasti A, Shariftabrizi A, Asgari M (2017)
Cytoplasmic expression of CD133 stemness marker is associated with tumor aggressiveness in clear cell renal cell carcinoma
Exp Mol Pathol, 103 (2), 218-228
PubMed 29050853

Saldova R, Haakensen VD, Rødland E, Walsh I, Stöckmann H, Engebraaten O, Børresen-Dale AL, Rudd PM (2017)
Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up
Mol Oncol, 11 (10), 1361-1379
PubMed 28657165

Samuel N, Id Said B, Guha T, Novokmet A, Li W, Silwal-Pandit L, Børrsen-Dale AL, Langerød A, Hudson TJ, Malkin D (2017)
Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk
Hum Mutat, 38 (3), 265-268
PubMed 27957778

Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
PubMed 28713640

Scott DW, Abrisqueta P, Wright GW, Slack GW, Mottok A, Villa D, Jares P, Rauert-Wunderlich H, Royo C, Clot G, Pinyol M, Boyle M, Chan FC, Braziel RM, Chan WC, Weisenburger DD, Cook JR, Greiner TC, Fu K, Ott G, Delabie J, Smeland EB, Holte H, Jaffe ES, Steidl C et al. (2017)
New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies
J Clin Oncol, 35 (15), 1668-1677
PubMed 28291392

Sellevold S, Peng Q, Fremstedal ASV, Berg K (2017)
Photochemical Internalization (PCI) of Bleomycin is Equally Effective in two Dissimilar Leiomyosarcoma Xenografts in Athymic Mice
Photodiagnosis Photodyn Ther (in press)
PubMed 28865875

Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
Hered Cancer Clin Pract, 15, 18
PubMed 29046738

Serguienko A, Hanes R, Grad I, Wang MY, Myklebost O, Munthe E (2017)
PP2A Regulatory Subunit B55γ is a Gatekeeper of Osteoblast Maturation and Lineage Maintenance
Stem Cells Dev, 26 (19), 1375-1383
PubMed 28805158

Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calléja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomäki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P et al. (2017)
BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
Cancer Res, 77 (11), 2789-2799
PubMed 28283652

Silwal-Pandit L, Langerød A, Børresen-Dale AL (2017)
TP53 Mutations in Breast and Ovarian Cancer
Cold Spring Harb Perspect Med, 7 (1)
PubMed 27815305

Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlitchting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen V, Langerød A, Lundgren S, Wist E, Naume B, Lingjærde OC, Børresen-Dale AL et al. (2017)
The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
Clin Cancer Res, 23 (16), 4662-4670
PubMed 28487444

Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
Exp Cell Res, 357 (1), 67-78
PubMed 28450044

Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
Gigascience, 6 (7), 1-12
PubMed 28459977

Skotland T, Sandvig K, Llorente A (2017)
Lipids in exosomes: Current knowledge and the way forward
Prog Lipid Res, 66, 30-41
PubMed 28342835

Smebye ML, Agostini A, Johannessen B, Thorsen J, Davidson B, Tropé CG, Heim S, Skotheim RI, Micci F (2017)
Involvement of DPP9 in gene fusions in serous ovarian carcinoma
BMC Cancer, 17 (1), 642
PubMed 28893231

Solheim O, Førsund M, Tropé CG, Kraggerud SM, Nesland JM, Davidson B (2017)
Epithelial-mesenchymal transition markers in malignant ovarian germ cell tumors
APMIS, 125 (9), 781-786
PubMed 28585395

Stacchiotti S, Mir O, Le Cesne A, Vincenzi B, Fedenko A, Maki RG, Somaiah N, Patel S, Brahmi M, Blay JY, Boye K, Sundby Hall K, Gelderblom H, Hindi N, Martin-Broto J, Kosela H, Rutkowski P, Italiano A, Duffaud F, Kobayashi E, Casali PG, Provenzano S, Kawai A (2017)
Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma
Oncologist (in press)
PubMed 28754721

Stuchlý J, Kanderová V, Vlková M, Heřmanová I, Slámová L, Pelák O, Taraldsrud E, Jílek D, Králíc Ková P, Fevang B, Trková M, Hrušák O, Froňková E, Šedivá A, Litzman J, Kalina T (2017)
Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia
Sci Rep, 7, 39710
PubMed 28054583

Stuchlý J, Kanderová V, Vlková M, Heřmanová I, Slámová L, Pelák O, Taraldsrud E, Jílek D, Králíčková P, Fevang B, Trková M, Hrušák O, Froňková E, Šedivá A, Litzman J, Kalina T (2017)
Erratum: Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia
Sci Rep, 7, 42569
PubMed 28240280

Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA (2017)
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Genome Med, 9 (1), 46
PubMed 28539123

Sveinbjørnsson B, Camilio KA, Haug BE, Rekdal Ø (2017)
LTX-315: a first-in-class oncolytic peptide that reprograms the tumor microenvironment
Future Med Chem, 9 (12), 1339-1344
PubMed 28490192

Taraldsrud E, Fevang B, Jørgensen SF, Moltu K, Hilden V, Taskén K, Aukrust P, Myklebust JH, Olweus J (2017)
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
J Autoimmun, 81, 110-119
PubMed 28476239

Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
A vital sugar code for ricin toxicity
Cell Res, 27 (11), 1351-1364
PubMed 28925387

Theodossiou TA, Olsen CE, Jonsson M, Kubin A, Hothersall JS, Berg K (2017)
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Redox Biol, 12, 191-197
PubMed 28254657

Thomsen M, Guren MG, Skovlund E, Glimelius B, Hjermstad MJ, Johansen JS, Kure E, Sorbye H, Pfeiffer P, Christoffersen T, Guren TK, Tveit KM (2017)
Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status
Eur J Cancer, 81, 26-35
PubMed 28595137

Thorvaldsen TE (2017)
Targeting Tankyrase to Fight WNT-dependent Tumours
Basic Clin Pharmacol Toxicol, 121 (2), 81-88
PubMed 28371398

Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
PLoS One, 12 (1), e0170508
PubMed 28107521

Torheim T, Malinen E, Hole KH, Lund KV, Indahl UG, Lyng H, Kvaal K, Futsaether CM (2017)
Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning
Acta Oncol, 56 (6), 806-812
PubMed 28464746

Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
J Cell Sci, 130 (17), 2867-2882
PubMed 28733455

Traxl A, Beikbaghban T, Wanek T, Kryeziu K, Pirker C, Mairinger S, Stanek J, Filip T, Sauberer M, Kuntner C, Berger W, Langer O (2017)
[(11)C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice
Nucl Med Biol, 52, 7-15
PubMed 28575795

Tusco R, Jacomin AC, Jain A, Penman BS, Larsen KB, Johansen T, Nezis IP (2017)
Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
Nat Commun, 8 (1), 1264
PubMed 29097655

Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E et al. (2017)
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
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PubMed 28591577

Urbanucci A, Mills IG (2017)
Bromodomain-containing proteins in prostate cancer
Mol Cell Endocrinol (in press)
PubMed 28624514

Vedeld HM, Merok M, Jeanmougin M, Danielsen SA, Honne H, Presthus GK, Svindland A, Sjo OH, Hektoen M, Eknaes M, Nesbakken A, Lothe RA, Lind GE (2017)
CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
Int J Cancer, 141 (5), 967-976
PubMed 28542846

Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
J Extracell Vesicles, 6 (1), 1344087
PubMed 28804597

Volchenkov R, Nygaard V, Sener Z, Skålhegg BS (2017)
Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
Front Immunol, 8, 698
PubMed 28674533

Wagner JA, Rosario M, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA (2017)
CD56bright NK cells exhibit potent antitumor responses following IL-15 priming
J Clin Invest, 127 (11), 4042-4058
PubMed 28972539

Walker SM, Knight LA, McCavigan AM, Logan GE, Berge V, Sherif A, Pandha H, Warren AY, Davidson C, Uprichard A, Blayney JK, Price B, Jellema GL, Steele CJ, Svindland A, McDade SS, Eden CG, Foster C, Mills IG, Neal DE, Mason MD, Kay EW, Waugh DJ, Harkin DP, Watson RW et al. (2017)
Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology
Eur Urol, 72 (4), 509-518
PubMed 28408174

Walseng E, Köksal H, Sektioglu IM, Fåne A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Wälchli S (2017)
A TCR-based Chimeric Antigen Receptor
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PubMed 28878363

Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø (2017)
A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
Exp Cell Res, 352 (2), 218-224
PubMed 28189639

Wegner CS, Hauge A, Gaustad JV, Andersen LMK, Simonsen TG, Galappathi K, Rofstad EK (2017)
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts
Acta Oncol, 1-9 (in press)
PubMed 28661213

Westrøm S, Generalov R, Bønsdorff TB, Larsen RH (2017)
Preparation of (212)Pb-labeled monoclonal antibody using a novel (224)Ra-based generator solution
Nucl Med Biol, 51, 1-9
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Wogsland CE, Greenplate AR, Kolstad A, Myklebust JH, Irish JM, Huse K (2017)
Mass Cytometry of Follicular Lymphoma Tumors Reveals Intrinsic Heterogeneity in Proteins Including HLA-DR and a Deficit in Nonmalignant Plasmablast and Germinal Center B-Cell Populations
Cytometry B Clin Cytom, 92 (1), 79-87
PubMed 27933753

Zhao S, Løvf M, Carm KT, Bakken AC, Hoff AM, Skotheim RI (2017)
Novel transcription-induced fusion RNAs in prostate cancer
Oncotarget, 8 (30), 49133-49143
PubMed 28467780

Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
G3 (Bethesda), 7 (6), 1753-1766
PubMed 28428242

Zuber V, Bettella F, Witoelar A, PRACTICAL Consortium, CRUK GWAS, BCAC Consortium, TRICL Consortium, Andreassen OA, Mills IG, Urbanucci A (2017)
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
BMC Genomics, 18 (1), 270
PubMed 28359301

Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Hansen Ree A, Edwin B, Nygaard V, Flatmark K (2017)
Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
Oncotarget, 8 (44), 76290-76304
PubMed 29100312

Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
Oncotarget, 8 (44), 76921-76934
PubMed 29100358