Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Division of Surgery, Inflammatory Medicine and Transplantation

55 publications found

Aimo A, Januzzi JL, Vergaro G, Richards AM, Lam CSP, Latini R, Anand IS, Cohn JN, Ueland T, Gullestad L, Aukrust P, Brunner-La Rocca HP, Bayes-Genis A, Lupón J, de Boer RA, Takeishi Y, Egstrup M, Gustafsson I, Gaggin HK, Eggers KM, Huber K, Gamble GD, Ling LH, Leong KTG, Yeo PSD et al. (2020)
Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T
Eur J Heart Fail
DOI 10.1002/ejhf.1701, PubMed 31919929

Al-Haidari G, Skovlund E, Undseth C, Rekstad BL, Larsen SG, Åsli LM, Dueland S, Malinen E, Guren MG (2020)
Re-irradiation for recurrent rectal cancer - a single-center experience
Acta Oncol, 1-7 (in press)
DOI 10.1080/0284186X.2020.1725111, PubMed 32056476

Alfonso JH, Afanou AK, Holm JØ, Stylianou E (2020)
Skin bioengineering in the diagnosis of occupational protein contact dermatitis
Occup Med (Lond) (in press)
DOI 10.1093/occmed/kqaa005, PubMed 32009172

Altunay IK, Özkur E, Dalgard FJ, Gieler U, Aragones LT, Lien L, Poot F, Jemec GB, Misery L, Szabó C, Linder D, Sampogna F, Evers AWM, Halvorsen JA, Balieva F, Szepietowski JC, Romanov DV, Marron SE, Finlay AY, Salek S, Kupfer J (2020)
Psychosocial Aspects of Adult Acne: Data from 13 European Countries
Acta Derm Venereol (in press)
DOI 10.2340/00015555-3409, PubMed 31993670

Amrutkar M, Larsen EK, Aasrum M, Finstadsveen AV, Andresen PA, Verbeke CS, Gladhaug IP (2020)
Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
Cells, 9 (1)
DOI 10.3390/cells9010227, PubMed 31963309

Asbun HJ, Moekotte AL, Vissers FL, Kunzler F, Cipriani F, Alseidi A, D'Angelica MI, Balduzzi A, Bassi C, Björnsson B, Boggi U, Callery MP, Del Chiaro M, Coimbra FJ, Conrad C, Cook A, Coppola A, Dervenis C, Dokmak S, Edil BH, Edwin B, Giulianotti PC, Han HS, Hansen PD, van der Heijde N et al. (2020)
The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection
Ann Surg, 271 (1), 1-14
DOI 10.1097/SLA.0000000000003590, PubMed 31567509

Beg S, Wronska E, Araujo I, Suárez BG, Ivanova E, Fedorov E, Aabakken L, Seitz U, Rey JF, Saurin JC, Tari R, Card T, Ragunath K (2020)
The use of rapid reading software to reduce capsule endoscopy reading times while maintaining accuracy
Gastrointest Endosc (in press)
DOI 10.1016/j.gie.2020.01.026, PubMed 31981645

Birketvedt K, Mikkelsen A, Klingen LL, Henriksen C, Helland IB, Emblem R (2020)
Nutritional Status in Adolescents with Esophageal Atresia
J Pediatr (in press)
DOI 10.1016/j.jpeds.2019.11.034, PubMed 31982089

Bjørnelv GMW, Edwin B, Fretland ÅA, Deb P, Aas E (2020)
Till death do us part: the effect of marital status on health care utilization and costs at end-of-life. A register study on all colorectal cancer decedents in Norway between 2009 and 2013
BMC Health Serv Res, 20 (1), 115
DOI 10.1186/s12913-019-4794-6, PubMed 32054492

Björnsson B, Hasselgren K, Røsok B, Larsen PN, Urdzik J, Schultz NA, Carling U, Fallentin E, Gilg S, Sandström P, Lindell G, Sparrelid E (2020)
Segment 4 occlusion in portal vein embolization increase future liver remnant hypertrophy - A Scandinavian cohort study
Int J Surg, 75, 60-65 (in press)
DOI 10.1016/j.ijsu.2020.01.129, PubMed 32001330

Bretthauer M, Kalager M (2020)
Disparities in Preventive Health Services: Targeting Minorities and Majorities
Ann Intern Med (in press)
DOI 10.7326/M19-3899, PubMed 31931529

Chahal-Kummen M, Salte OBK, Hewitt S, Blom-Høgestøl IK, Risstad H, Kristinsson J, Mala T (2020)
Health benefits and risks during 10 years after Roux-en-Y gastric bypass
Surg Endosc (in press)
DOI 10.1007/s00464-019-07328-2, PubMed 31993812

Chandra A, Midtvedt K, Åsberg A, Eide IA (2020)
The Authors' Reply
Transplantation (in press)
DOI 10.1097/TP.0000000000003120, PubMed 31972700

Dahl KG, Andersen MH, Urstad KH, Falk RS, Engebretsen E, Wahl AK (2020)
Identifying Core Variables Associated With Health Literacy in Kidney Transplant Recipients
Prog Transplant, 30 (1), 38-47
DOI 10.1177/1526924819893285, PubMed 31918615

Dahl AA, Brennhovd B, Fosså SD, Axcrona K (2020)
A cross-sectional study of current work ability after radical prostatectomy
BMC Urol, 20 (1), 9
DOI 10.1186/s12894-020-0579-9, PubMed 32005115

Dahle DO, Mjoen G (2020)
The salutary blood pressure of a solitary kidney
Am J Hypertens (in press)
DOI 10.1093/ajh/hpaa004, PubMed 31907513

Dueland S, Syversveen T, Solheim JM, Solberg S, Grut H, Bjørnbeth BA, Hagness M, Line PD (2020)
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg, 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404, PubMed 31188200

Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
MirGeneDB 2.0: the metazoan microRNA complement
Nucleic Acids Res, 48 (D1), D1172
DOI 10.1093/nar/gkz1016, PubMed 31642479

Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
MirGeneDB 2.0: the metazoan microRNA complement
Nucleic Acids Res, 48 (D1), D132-D141
DOI 10.1093/nar/gkz885, PubMed 31598695

Gelpi M, Ueland PM, Trøseid M, Mocroft A, Lebech AM, Ullum H, Midttun Ø, Lundgren J, Nielsen SD (2020)
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus
J Infect Dis, 221 (3), 419-427
DOI 10.1093/infdis/jiz465, PubMed 31538186

Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
Impact of Hiv-Related Gut Microbiota Alterations on Metabolic Comorbidities
Clin Infect Dis (in press)
DOI 10.1093/cid/ciz1235, PubMed 31894240

Gjerde A, Lillås BS, Marti HP, Reisæter AV, Vikse BE (2020)
Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life
Nephrol Dial Transplant (in press)
DOI 10.1093/ndt/gfaa001, PubMed 32040151

Gjersvik P, Landrø L, Roscher I (2020)
Bli ikke solbrent
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0795, PubMed 31948212

Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities
Hepatology (in press)
DOI 10.1002/hep.31110, PubMed 31925805

Golse N, Joly F, Nicolas Q, Vibert E, Line PD, Clementel IV (2020)
Partial orthotopic liver transplantation in combination with two-stage hepatectomy: A proof-of-concept explained by mathematical modeling
Clin Biomech (Bristol, Avon), 73, 195-200 (in press)
DOI 10.1016/j.clinbiomech.2020.01.020, PubMed 32035308

Grummet J, Gorin MA, Popert R, O'Brien T, Lamb AD, Hadaschik B, Radtke JP, Wagenlehner F, Baco E, Moore CM, Emberton M, George AK, Davis JW, Szabo RJ, Buckley R, Loblaw A, Allaway M, Kastner C, Briers E, Royce PL, Frydenberg M, Murphy DG, Woo HH (2020)
"TREXIT 2020": why the time to abandon transrectal prostate biopsy starts now
Prostate Cancer Prostatic Dis
DOI 10.1038/s41391-020-0204-8, PubMed 31932659

Haller MC, Wallisch C, Mjøen G, Holdaas H, Dunkler D, Heinze G, Oberbauer R (2020)
Predicting donor, recipient and graft survival in living donor kidney transplantation to inform pre-transplant counseling: the donor and recipient linked iPREDICTLIVING tool - a retrospective study
Transpl Int (in press)
DOI 10.1111/tri.13580, PubMed 31970822

Haugen AJ, Hallan S, Langberg NE, Dahle DO, Pihlstrøm H, Birkeland KI, Reisaeter A, Midtvedt K, Hartmann A, Holdaas H, Mjøen G (2020)
Increased long-term risk for hypertension in kidney donors - a retrospective cohort study
Transpl Int
DOI 10.1111/tri.13576, PubMed 31958170

Hoel H, Ueland T, Hove-Skovsgaard M, Hartling HJ, Gelpi M, Benfield T, Ullum H, Michelsen AE, Aukrust P, Nielsen SD, Trøseid M (2020)
Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
Open Forum Infect Dis, 7 (2), ofaa033
DOI 10.1093/ofid/ofaa033, PubMed 32055642

Hoel H, Ueland T, Knudsen A, Kjær A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Trøseid M (2020)
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280

Holmen H, Larsen MH, Sallinen MH, Thoresen L, Ahlsen B, Andersen MH, Borge CR, Eik H, Wahl AK, Mengshoel AM (2020)
Working with patients suffering from chronic diseases can be a balancing act for health care professionals - a meta-synthesis of qualitative studies
BMC Health Serv Res, 20 (1), 98
DOI 10.1186/s12913-019-4826-2, PubMed 32039723

Iordanova Schistad E, Kong XY, Furberg AS, Bäckryd E, Grimnes G, Emaus N, Rosseland LA, Gordh T, Stubhaug A, Engdahl B, Halvorsen B, Nielsen CS (2020)
A population-based study of inflammatory mechanisms and pain sensitivity
Pain, 161 (2), 338-350
DOI 10.1097/j.pain.0000000000001731, PubMed 31651577

Kalager M, Bretthauer M (2020)
Improving cancer screening programs
Science, 367 (6474), 143-144
DOI 10.1126/science.aay3156, PubMed 31919207

Klaasen RA, Bergan S, Bremer S, Hole K, Nordahl CB, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2020)
PHARMACODYNAMIC ASSESSMENT OF MYCOPHENOLIC ACID IN RESTING AND ACTIVATED TARGET CELL POPULATION DURING THE FIRST YEAR AFTER RENAL TRANSPLANTATION
Br J Clin Pharmacol (in press)
DOI 10.1111/bcp.14218, PubMed 31925806

Legøy TA, Vethe H, Abadpour S, Strand BL, Scholz H, Paulo JA, Ræder H, Ghila L, Chera S (2020)
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Sci Rep, 10 (1), 414
DOI 10.1038/s41598-019-57305-x, PubMed 31942009

Lie A, Gjerstad AC, Fossum V, Teigen C, Skari H, Aden P, Bjerre A (2020)
Lower urinary tract dysfunction in children - a practical approach
Tidsskr Nor Laegeforen, 140 (2)
DOI 10.4045/tidsskr.18.0565, PubMed 32026859

Lorentzen EM, Henriksen S, Kaur A, Kro GB, Hammarström C, Hirsch HH, Midtvedt K, Rinaldo CH (2020)
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Virol J, 17 (1), 5
DOI 10.1186/s12985-019-1275-9, PubMed 31924245

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12596, PubMed 31978943

Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L (2020)
Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study
Transplantation, 104 (1), 190-196
DOI 10.1097/TP.0000000000002777, PubMed 31365472

Nordheim E, Dahle DO, Halden T, Birkeland KI, Åsberg A, Hartmann A, Horneland R, Geir Jenssen T (2020)
Endothelial function after pancreas transplantation - a single center observational study
Clin Transplant, e13815 (in press)
DOI 10.1111/ctr.13815, PubMed 32027399

Olesen SS, Poulsen JL, Novovic S, Nojgaard C, Kalaitzakis E, Jensen NM, Engjom T, Tjora E, Waage A, Hauge T, Haas SL, Vujasinovic M, Barauskas G, Pukitis A, Ozola-Zalite I, Okhlobystin A, Parhiala M, Laukkarinen J, Drewes AM, Scandinavian Baltic Pancreatic Clu (2020)
Multiple risk factors for diabetes mellitus in patients with chronic pancreatitis: A multicentre study of 1117 cases
United European Gastroenterol. J., UNSP 2050640620901973

Ossum AM, Palm Ø, Cvancarova M, Bernklev T, Jahnsen J, Moum B, Høivik ML, IBSEN Study Group (2020)
The Impact of Spondyloarthritis and Joint Symptoms on Health-Related Quality of Life and Fatigue in IBD Patients. Results From a Population-Based Inception Cohort (20-Year Follow-up in the Ibsen Study)
Inflamm Bowel Dis, 26 (1), 114-124
DOI 10.1093/ibd/izz105, PubMed 31127829

Otterdal K, Berg A, Michelsen AE, Patel S, Gregersen I, Sagen EL, Halvorsen B, Yndestad A, Ueland T, Langeland N, Aukrust P (2020)
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363

Reikvam DH, Meyer-Myklestad MH, Trøseid M, Stiksrud B (2020)
Probiotics to manage inflammation in HIV infection
Curr Opin Infect Dis, 33 (1), 34-43
DOI 10.1097/QCO.0000000000000612, PubMed 31789692

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun (in press)
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Skrede OJ, De Raedt S, Kleppe A, Hveem TS, Liestøl K, Maddison J, Askautrud HA, Pradhan M, Nesheim JA, Albregtsen F, Farstad IN, Domingo E, Church DN, Nesbakken A, Shepherd NA, Tomlinson I, Kerr R, Novelli M, Kerr DJ, Danielsen HE (2020)
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
Lancet, 395 (10221), 350-360
DOI 10.1016/S0140-6736(19)32998-8, PubMed 32007170

Syversen SW, Goll GL, Jørgensen KK, Olsen IC, Sandanger Ø, Gehin JE, Warren DJ, Sexton J, Mørk C, Jahnsen J, Kvien TK, Bolstad N, Haavardsholm EA (2020)
Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (the NOR-DRUM study)
Trials, 21 (1), 13
DOI 10.1186/s13063-019-3734-4, PubMed 31907007

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20 (in press)
DOI 10.1159/000504529, PubMed 32028277

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

Thyssen JP, Berents T, Bradley M, Deleuran M, Grimstad Ø, Korhonen L, Langeland T, Särnhult T, Thomsen SF, Thune T, Wahlgren CF, Vestergaard C, Kobyletzki LB, Remitz A (2020)
Clinical Management of Atopic Dermatitis in Adults: Mapping of Expert Opinion in 4 Nordic Countries using a Modified Delphi Process
Acta Derm Venereol, 100 (1), adv00015
DOI 10.2340/00015555-3369, PubMed 31709450

Ting YT, Dahal-Koirala S, Kim HSK, Qiao SW, Neumann RS, Lundin KEA, Petersen J, Reid HH, Sollid LM, Rossjohn J (2020)
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305

Trimboli P, Castellana M, Virili C, Havre RF, Bini F, Marinozzi F, D'Ambrosio F, Giorgino F, Giovanella L, Prosch H, Grani G, Radzina M, Cantisani V (2020)
Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference
Radiol Med
DOI 10.1007/s11547-019-01129-2, PubMed 31970579

Ueland T, Estensen ME, Grindheim G, Bollerslev J, Henriksen T, Aukrust P, Aakhus S, Gullestad L, Lekva T (2020)
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens (in press)
DOI 10.1097/HJH.0000000000002362, PubMed 31990902

Wasmuth HH, Faerden AE, Myklebust TA, Pfeffer F, Norderval S, Riis R, Olsen OC, Lambrecht JR, Korner H, Larsen SG, Forsmo HM, Baekkelund O, Lavik S, Knapp JC, Sjo O, Rashid G, Norwegian TaTME Collaborative Grp Norwegian Colorectal Canc Grp (2020)
Transanal total mesorectal excision for rectal cancer has been suspended in Norway
Br. J. Surg., 107 (1), 121-130

Zhao J, Li X, Liu L, Cao J, Goscinski MA, Fan H, Li H, Suo Z (2020)
Oncogenic Role of Guanylate Binding Protein 1 in Human Prostate Cancer
Front Oncol, 9, 1494
DOI 10.3389/fonc.2019.01494, PubMed 31998647

 
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