Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Center for Clinical Heart Research

24 publications found

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2018)
Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study
Diabetol Metab Syndr, 10, 59
DOI 10.1186/s13098-018-0360-3, PubMed 30038669

Bethke A, Shanmuganathan L, Shetelig C, Swanson D, Andersen GØ, Eritsland J, Kløw NE, Hoffmann P (2018)
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI
PLoS One, 13 (11), e0206723
DOI 10.1371/journal.pone.0206723, PubMed 30412607

Cwikiel J, Seljeflot I, Berge E, Njerve IU, Ulsaker H, Arnesen H, Flaa A (2018)
Effect of strenuous exercise on mediators of inflammation in patients with coronary artery disease
Cytokine, 105, 17-22
DOI 10.1016/j.cyto.2018.02.006, PubMed 29433015

Danielsen SO, Moons P, Sandven I, Leegaard M, Solheim S, Tønnessen T, Lie I (2018)
Thirty-day readmissions in surgical and transcatheter aortic valve replacement: A systematic review and meta-analysis
Int J Cardiol, 268, 85-91
DOI 10.1016/j.ijcard.2018.05.026, PubMed 29779575

Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
Liver Int (in press)
DOI 10.1111/liv.13979, PubMed 30269440

Engeseth K, Prestgaard EE, Mariampillai JE, Grundvold I, Liestol K, Kjeldsen SE, Bodegard J, Erikssen JE, Gjesdal K, Skretteberg PT (2018)
Physical fitness is a modifiable predictor of early cardiovascular death: A 35-year follow-up study of 2014 healthy middle-aged men
Eur J Prev Cardiol, 25 (15), 1655-1663
DOI 10.1177/2047487318793459, PubMed 30103630

Hansen CH, Ritschel V, Andersen GØ, Halvorsen S, Eritsland J, Arnesen H, Seljeflot I (2018)
Markers of Thrombin Generation Are Associated With Long-Term Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction
Clin Appl Thromb Hemost, 24 (7), 1088-1094
DOI 10.1177/1076029618764847, PubMed 29695176

Heier M, Espeland CN, Brunborg C, Seljeflot I, Margeirsdottir HD, Hanssen KF, Fugelseth D, Dahl-Jørgensen K (2018)
Preserved endothelial function in young adults with type 1 diabetes
PLoS One, 13 (10), e0206523
DOI 10.1371/journal.pone.0206523, PubMed 30359432

Heier M, Stensæth KH, Brunborg C, Seljeflot I, Margeirsdottir HD, Hanssen KF, Dahl-Jørgensen K (2018)
Increased arterial stiffness in childhood onset diabetes: a cardiovascular magnetic resonance study
Eur Heart J Cardiovasc Imaging, 19 (6), 694-700
DOI 10.1093/ehjci/jex178, PubMed 28950341

Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976

Horjen AW, Ulimoen SR, Norseth J, Svendsen JH, Smith P, Arnesen H, Seljeflot I, Tveit A (2018)
High-sensitivity troponin I in persistent atrial fibrillation - relation to NT-proBNP and markers of inflammation and haemostasis
Scand J Clin Lab Invest, 78 (5), 386-392
DOI 10.1080/00365513.2018.1481224, PubMed 29933716

Langseth MS, Opstad TB, Bratseth V, Solheim S, Arnesen H, Pettersen AÅ, Seljeflot I, Helseth R (2018)
Markers of neutrophil extracellular traps are associated with adverse clinical outcome in stable coronary artery disease
Eur J Prev Cardiol, 25 (7), 762-769
DOI 10.1177/2047487318760618, PubMed 29473463

Mariampillai JE, Prestgaard EE, Kjeldsen SE, Liestøl K, Engeseth K, Erikssen J, Bodegard J, Berge E, Grundvold I, Skretteberg PT (2018)
SBP above 180 mmHg at moderate exercise workload increases coronary heart disease risk in healthy men during 28-year follow-up
J Hypertens (in press)
DOI 10.1097/HJH.0000000000001959, PubMed 30325341

Mayerhofer CCK, Awoyemi AO, Moscavitch SD, Lappegård KT, Hov JR, Aukrust P, Hovland A, Lorenzo A, Halvorsen S, Seljeflot I, Gullestad L, Trøseid M, Broch K (2018)
Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
ESC Heart Fail, 5 (5), 977-984
DOI 10.1002/ehf2.12332, PubMed 30088346

Munkhaugen J, Hjelmesæth J, Otterstad JE, Helseth R, Sollid ST, Gjertsen E, Gullestad L, Perk J, Moum T, Husebye E, Dammen T (2018)
Managing patients with prediabetes and type 2 diabetes after coronary events: individual tailoring needed - a cross-sectional study
BMC Cardiovasc Disord, 18 (1), 160
DOI 10.1186/s12872-018-0896-z, PubMed 30075751

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279

Rocca B, Fox KAA, Ajjan RA, Andreotti F, Baigent C, Collet JP, Grove EL, Halvorsen S, Huber K, Morais J, Patrono C, Rubboli A, Seljeflot I, Sibbing D, Siegbahn A, Ten Berg J, Vilahur G, Verheugt FWA, Wallentin L, Weiss TW, Wojta J, Storey RF (2018)
Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis
Eur Heart J, 39 (19), 1672-1686f
DOI 10.1093/eurheartj/ehy066, PubMed 29509886

Røe ÅT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Nordén ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Øystein Andersen G, Sjaastad I, Louch WE (2018)
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res (in press)
DOI 10.1093/cvr/cvy257, PubMed 30351410

Saetre E, Abdelnoor M (2018)
Incidence rate of sudden death in epilepsy: A systematic review and meta-analysis
Epilepsy Behav, 86, 193-199
DOI 10.1016/j.yebeh.2018.06.037, PubMed 30017838

Shetelig C, Limalanathan S, Hoffmann P, Seljeflot I, Gran JM, Eritsland J, Andersen GØ (2018)
Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI
J Am Coll Cardiol, 72 (2), 187-198
DOI 10.1016/j.jacc.2018.04.053, PubMed 29976293

Staer-Jensen H, Sunde K, Nakstad ER, Eritsland J, Andersen GØ (2018)
Comparison of three haemodynamic monitoring methods in comatose post cardiac arrest patients
Scand Cardiovasc J, 52 (3), 141-148
DOI 10.1080/14017431.2018.1450992, PubMed 29544369

Åkra S, Aksnes TA, Flaa A, Eggesbø HB, Opstad TB, Njerve IU, Seljeflot I (2018)
Interleukin-18 and the NLR family pyrin domain containing-3 inflammasome in adipose tissue are strongly associated with glucometabolic variables in a cohort of middle-aged men
Diab Vasc Dis Res, 15 (5), 458-464
DOI 10.1177/1479164118785307, PubMed 29972041

 
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