Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2014 from OUS - Photochemical Internalisation (PCI)

10 publications found

Bostad M, Kausberg M, Weyergang A, Olsen CE, Berg K, Høgset A, Selbo PK (2014)
Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
Mol Pharm, 11 (8), 2764-76
DOI 10.1021/mp500129t, PubMed 24960585

Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464

Håkerud M, Selbo PK, Waeckerle-Men Y, Contassot E, Dziunycz P, Kündig TM, Høgset A, Johansen P (2014)
Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells
J Control Release, 198, 10-7
DOI 10.1016/j.jconrel.2014.11.032, PubMed 25482339

Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727

Paleos CM, Sideratou Z, Theodossiou TA, Tsiourvas D (2014)
Carboxylated hydroxyethyl starch: a novel polysaccharide for the delivery of doxorubicin
Chem Biol Drug Des, 85 (5), 653-8
DOI 10.1111/cbdd.12447, PubMed 25303215

Repetto-Llamazares AH, Larsen RH, Giusti AM, Riccardi E, Bruland ØS, Selbo PK, Dahle J (2014)
177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice
PLoS One, 9 (7), e103070
DOI 10.1371/journal.pone.0103070, PubMed 25068508

Wang F, Zamora G, Sun CH, Trinidad A, Berg K, Madsen SJ, Kwon YJ, Hirschberg H (2014)
Photochemical internalization (PCI) enhanced nonviral transfection of tumor suppressor and pro-drug activating genes; a potential treatment modality for gliomas.
PROC SPIE, 8928, UNSP 89280B

Wang F, Zamora G, Sun CH, Trinidad A, Chun C, Kwon YJ, Berg K, Madsen SJ, Hirschberg H (2014)
Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene
J Neurooncol, 118 (1), 29-37
DOI 10.1007/s11060-014-1410-9, PubMed 24610460

Weyergang A, Cheung LH, Rosenblum MG, Mohamedali KA, Peng Q, Waltenberger J, Berg K (2014)
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010

Zamora G, Wang F, Sun CH, Trinidad A, Kwon YJ, Cho SK, Berg K, Madsen SJ, Hirschberg H (2014)
Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier
J Biomed Opt, 19 (10), 105009
DOI 10.1117/1.JBO.19.10.105009, PubMed 25341069

 
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