Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2014 from OUS - Department of Radiation Biology

31 publications found

Anda S, Boye E, Grallert B (2014)
Cell-cycle analyses using thymidine analogues in fission yeast
PLoS One, 9 (2), e88629
DOI 10.1371/journal.pone.0088629, PubMed 24551125

Bostad M, Kausberg M, Weyergang A, Olsen CE, Berg K, Høgset A, Selbo PK (2014)
Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
Mol Pharm, 11 (8), 2764-76
DOI 10.1021/mp500129t, PubMed 24960585

Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464

Coelho SC, Rocha S, Pereira MC, Juzenas P, Coelho MA (2014)
Enhancing proteasome-lnhibitor effect by functionalized gold nanoparticles
J Biomed Nanotechnol, 10 (4), 717-23
DOI 10.1166/jbn.2014.1743, PubMed 24734524

Edin NJ, Sandvik JA, Cheng C, Bergersen L, Pettersen EO (2014)
The roles of TGF-β3 and peroxynitrite in removal of hyper-radiosensitivity by priming irradiation
Int J Radiat Biol, 90 (7), 527-37
DOI 10.3109/09553002.2014.906767, PubMed 24650070

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK (2014)
Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts
Microvasc Res, 98, 159-65
DOI 10.1016/j.mvr.2014.02.005, PubMed 24555949

Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
Int J Cancer, 135 (9), 2085-95
DOI 10.1002/ijc.28862, PubMed 24658971

Hompland T, Ellingsen C, Galappathi K, Rofstad EK (2014)
DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts
BMC Cancer, 14, 92
DOI 10.1186/1471-2407-14-92, PubMed 24528854

Hompland T, Lund KV, Ellingsen C, Kristensen GB, Rofstad EK (2014)
Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
Radiother Oncol, 113 (1), 132-8
DOI 10.1016/j.radonc.2014.09.011, PubMed 25443501

Håkerud M, Selbo PK, Waeckerle-Men Y, Contassot E, Dziunycz P, Kündig TM, Høgset A, Johansen P (2014)
Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells
J Control Release, 198, 10-7
DOI 10.1016/j.jconrel.2014.11.032, PubMed 25482339

Juzeniene A, Baturaite Z, Moan J (2014)
Sun exposure and melanomas on sun-shielded and sun-exposed body areas
Adv Exp Med Biol, 810, 375-89
PubMed 25207377

Juzeniene A, Grigalavicius M, Baturaite Z, Moan J (2014)
Minimal and maximal incidence rates of skin cancer in Caucasians estimated by use of sigmoidal UV dose-incidence curves
Int J Hyg Environ Health, 217 (8), 839-44
DOI 10.1016/j.ijheh.2014.06.002, PubMed 25023193

Lund-Andersen C, Patzke S, Nähse-Kumpf V, Syljuåsen RG (2014)
PLK1-inhibition can cause radiosensitization or radioresistance dependent on the treatment schedule
Radiother Oncol, 110 (2), 355-61
DOI 10.1016/j.radonc.2013.12.014, PubMed 24502970

Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727

Moan J, Grigalavicius M, Baturaite Z, Dahlback A, Juzeniene A (2014)
The relationship between UV exposure and incidence of skin cancer
Photodermatol Photoimmunol Photomed, 31 (1), 26-35
DOI 10.1111/phpp.12139, PubMed 25213656

Moan J, Grigalavicius M, Dahlback A, Baturaite Z, Juzeniene A (2014)
Ultraviolet-radiation and health: optimal time for sun exposure
Adv Exp Med Biol, 810, 423-8
PubMed 25207380

Moan JE, Baturaite Z, Dahlback A, Porojnicu AC (2014)
Ultraviolet radiation and cutaneous malignant melanoma
Adv Exp Med Biol, 810, 359-74
PubMed 25207376

Nilsen LB, Fangberget A, Geier OM, Engebraaten O, Borgen E, Olsen DR, Seierstad T (2014)
Associations between tumor vascularization assessed by in vivo DCE-MRI and the presence of disseminated tumor cells in bone marrow in breast cancer patients at the time of diagnosis
J Magn Reson Imaging, 40 (6), 1382-91
DOI 10.1002/jmri.24502, PubMed 24470360

Paleos CM, Sideratou Z, Theodossiou TA, Tsiourvas D (2014)
Carboxylated hydroxyethyl starch: a novel polysaccharide for the delivery of doxorubicin
Chem Biol Drug Des, 85 (5), 653-8
DOI 10.1111/cbdd.12447, PubMed 25303215

Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, Landazuri MO, Görlach A, Flamm H, Kieninger J, Urban G, Weltin A, Singleton DC, Haider S, Buffa FM, Harris AL et al. (2014)
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
J Enzyme Inhib Med Chem, 30 (5), 689-721
DOI 10.3109/14756366.2014.966704, PubMed 25347767

Ragnum HB, Vlatkovic L, Lie AK, Axcrona K, Julin CH, Frikstad KM, Hole KH, Seierstad T, Lyng H (2014)
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
Br J Cancer, 112 (2), 382-90
DOI 10.1038/bjc.2014.604, PubMed 25461803

Repetto-Llamazares AH, Larsen RH, Giusti AM, Riccardi E, Bruland ØS, Selbo PK, Dahle J (2014)
177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice
PLoS One, 9 (7), e103070
DOI 10.1371/journal.pone.0103070, PubMed 25068508

Rofstad EK, Galappathi K, Mathiesen BS (2014)
Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis
Neoplasia, 16 (7), 586-94
DOI 10.1016/j.neo.2014.07.003, PubMed 25117980

Shulzhenko N, Lyng H, Sanson GF, Morgun A (2014)
Ménage à trois: an evolutionary interplay between human papillomavirus, a tumor, and a woman
Trends Microbiol, 22 (6), 345-53
DOI 10.1016/j.tim.2014.02.009, PubMed 24674660

Sternemalm J, Russnes HG, Zhao X, Risberg B, Nord S, Caldas C, Børresen-Dale AL, Stokke T, Patzke S (2014)
Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
Br J Cancer, 111 (2), 326-38
DOI 10.1038/bjc.2014.297, PubMed 24901235

Torheim T, Malinen E, Kvaal K, Lyng H, Indahl UG, Andersen EK, Futsaether CM (2014)
Classification of dynamic contrast enhanced MR images of cervical cancers using texture analysis and support vector machines
IEEE Trans Med Imaging, 33 (8), 1648-56
DOI 10.1109/TMI.2014.2321024, PubMed 24802069

Wang F, Zamora G, Sun CH, Trinidad A, Berg K, Madsen SJ, Kwon YJ, Hirschberg H (2014)
Photochemical internalization (PCI) enhanced nonviral transfection of tumor suppressor and pro-drug activating genes; a potential treatment modality for gliomas.
PROC SPIE, 8928, UNSP 89280B

Wang F, Zamora G, Sun CH, Trinidad A, Chun C, Kwon YJ, Berg K, Madsen SJ, Hirschberg H (2014)
Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene
J Neurooncol, 118 (1), 29-37
DOI 10.1007/s11060-014-1410-9, PubMed 24610460

Weyergang A, Cheung LH, Rosenblum MG, Mohamedali KA, Peng Q, Waltenberger J, Berg K (2014)
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010

Zamora G, Wang F, Sun CH, Trinidad A, Kwon YJ, Cho SK, Berg K, Madsen SJ, Hirschberg H (2014)
Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier
J Biomed Opt, 19 (10), 105009
DOI 10.1117/1.JBO.19.10.105009, PubMed 25341069

Zou X, Yao M, Ma L, Hossu M, Han X, Juzenas P, Chen W (2014)
X-ray-induced nanoparticle-based photodynamic therapy of cancer
Nanomedicine (Lond), 9 (15), 2339-51
DOI 10.2217/nnm.13.198, PubMed 24471504

 
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