Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Rheumatology, Dermatology and Infectious Diseases

28 publications found

Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun (in press)
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548

Alfonso JH, Afanou AK, Holm JØ, Stylianou E (2020)
Skin bioengineering in the diagnosis of occupational protein contact dermatitis
Occup Med (Lond) (in press)
DOI 10.1093/occmed/kqaa005, PubMed 32009172

Altunay IK, Özkur E, Dalgard FJ, Gieler U, Tomas Aragones L, Lien L, Poot F, Jemec GB, Misery L, Szabó C, Linder D, Sampogna F, Evers AWM, Halvorsen JA, Balieva F, Szepietowski JC, Romanov DV, Marron SE, Finlay AY, Salek S, Kupfer J (2020)
Psychosocial Aspects of Adult Acne: Data from 13 European Countries
Acta Derm Venereol, 100 (4), adv00051
DOI 10.2340/00015555-3409, PubMed 31993670

Berg A, Patel S, Tellevik MG, Haanshuus CG, Dalen I, Otterdal K, Ueland T, Moyo SJ, Aukrust P, Langeland N (2020)
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Infection
DOI 10.1007/s15010-020-01399-3, PubMed 32077073

Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Furu K, Juzeniene A, Roscher I, Larsen IK, Green AC, Veierød MB, Robsahm TE (2020)
Use of Antidepressants and Risk of Cutaneous Melanoma: A Prospective Registry-Based Case-Control Study
Clin Epidemiol, 12, 193-202
DOI 10.2147/CLEP.S241249, PubMed 32110111

de Jesus AA, Hou Y, Brooks S, Malle L, Biancotto A, Huang Y, Calvo KR, Marrero B, Moir S, Oler AJ, Deng Z, Montealegre Sanchez GA, Ahmed A, Allenspach E, Arabshahi B, Behrens E, Benseler S, Bezrodnik L, Bout-Tabaku S, Brescia AC, Brown D, Burnham JM, Caldirola MS, Carrasco R, Chan AY et al. (2020)
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
J Clin Invest (in press)
DOI 10.1172/JCI129301, PubMed 31874111

Distler O, Assassi S, Cottin V, Cutolo M, Danoff SK, Denton CP, Distler JHW, Hoffmann-Vold AM, Johnson SR, Müller Ladner U, Smith V, Volkmann ER, Maher TM (2020)
Predictors of progression in systemic sclerosis patients with interstitial lung disease
Eur Respir J (in press)
DOI 10.1183/13993003.02026-2019, PubMed 32079645

Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Molberg Ø, Hoffmann-Vold AM (2020)
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Rheumatology (Oxford) (in press)
DOI 10.1093/rheumatology/keaa026, PubMed 32097470

Gelpi M, Ueland PM, Trøseid M, Mocroft A, Lebech AM, Ullum H, Midttun Ø, Lundgren J, Nielsen SD (2020)
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus
J Infect Dis, 221 (3), 419-427
DOI 10.1093/infdis/jiz465, PubMed 31538186

Gjersvik P (2020)
Three weeks in the sun
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.20.0055, PubMed 32105025

Gjersvik P, Landrø L, Roscher I (2020)
Don’t get sunburnt
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0795, PubMed 31948212

Hoel H, Ueland T, Hove-Skovsgaard M, Hartling HJ, Gelpi M, Benfield T, Ullum H, Michelsen AE, Aukrust P, Nielsen SD, Trøseid M (2020)
Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
Open Forum Infect Dis, 7 (2), ofaa033
DOI 10.1093/ofid/ofaa033, PubMed 32055642

Hoel H, Ueland T, Knudsen A, Kjær A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Trøseid M (2020)
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280

Hunderi JOG, Rolfsjord LB, Carlsen KCL, Holst R, Bakkeheim E, Berents TL, Carlsen KH, Skjerven HO (2020)
Virus, allergic sensitisation and cortisol in infant bronchiolitis and risk of early asthma
ERJ Open Res, 6 (1)
DOI 10.1183/23120541.00268-2019, PubMed 32201686

Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkaa115, PubMed 32083667

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12596, PubMed 31978943

Ossum AM, Palm Ø, Cvancarova M, Bernklev T, Jahnsen J, Moum B, Høivik ML, IBSEN Study Group (2020)
The Impact of Spondyloarthritis and Joint Symptoms on Health-Related Quality of Life and Fatigue in IBD Patients. Results From a Population-Based Inception Cohort (20-Year Follow-up in the Ibsen Study)
Inflamm Bowel Dis, 26 (1), 114-124
DOI 10.1093/ibd/izz105, PubMed 31127829

Otterdal K, Berg A, Michelsen AE, Patel S, Gregersen I, Sagen EL, Halvorsen B, Yndestad A, Ueland T, Langeland N, Aukrust P (2020)
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363

Pereira MP, Hoffmann V, Weisshaar E, Wallengren J, Halvorsen JA, Garcovich S, Misery L, Brenaut E, Savk E, Potekaev N, Lvov A, Bobko S, Szepietowski JC, Reich A, Bozek A, Legat FJ, Metz M, Streit M, Serra-Baldrich E, Gonçalo M, Storck M, Greiwe I, Nau T, Steinke S, Dugas M et al. (2020)
Chronic Nodular Prurigo: Clinical Profile and Burden. A European Cross-sectional Study
J Eur Acad Dermatol Venereol (in press)
DOI 10.1111/jdv.16309, PubMed 32078192

Reikvam DH, Meyer-Myklestad MH, Trøseid M, Stiksrud B (2020)
Probiotics to manage inflammation in HIV infection
Curr Opin Infect Dis, 33 (1), 34-43
DOI 10.1097/QCO.0000000000000612, PubMed 31789692

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Skjerven HO, Rehbinder EM, Vettukattil R, LeBlanc M, Granum B, Haugen G, Hedlin G, Landrø L, Marsland BJ, Rudi K, Sjøborg KD, Söderhäll C, Staff AC, Carlsen KH, Asarnoj A, Bains KES, Carlsen OCL, Endre KMA, Granlund PA, Hermansen JU, Gudmundsdóttir HK, Hilde K, Håland G, Kreyberg I, Olsen IC et al. (2020)
Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial
Lancet, 395 (10228), 951-961
DOI 10.1016/S0140-6736(19)32983-6, PubMed 32087121

Syversen SW, Goll GL, Jørgensen KK, Olsen IC, Sandanger Ø, Gehin JE, Warren DJ, Sexton J, Mørk C, Jahnsen J, Kvien TK, Bolstad N, Haavardsholm EA (2020)
Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (the NOR-DRUM study)
Trials, 21 (1), 13
DOI 10.1186/s13063-019-3734-4, PubMed 31907007

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

Thyssen JP, Berents T, Bradley M, Deleuran M, Grimstad Ø, Korhonen L, Langeland T, Särnhult T, Thomsen SF, Thune T, Wahlgren CF, Vestergaard C, Kobyletzki LB, Remitz A (2020)
Clinical Management of Atopic Dermatitis in Adults: Mapping of Expert Opinion in 4 Nordic Countries using a Modified Delphi Process
Acta Derm Venereol, 100 (1), adv00015
DOI 10.2340/00015555-3369, PubMed 31709450

Ueland T, Roland MCP, Michelsen AE, Godang K, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2020)
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

 
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