Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Transplantation Medicine

38 publications found

Amini M, Niemi E, Hisdal J, Kalvøy H, Tronstad C, Scholz H, Rosales A, Martinsen OG (2020)
Monitoring the quality of frozen-thawed venous segments using bioimpedance spectroscopy
Physiol Meas (in press)
DOI 10.1088/1361-6579/ab85b7, PubMed 32235072

Barua I, Berset IP, Hære P, Wensaas KA, Bretthauer M (2020)
Nasjonalt screeningprogram for tarmkreft
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0658, PubMed 32105033

Beg S, Wronska E, Araujo I, Suárez BG, Ivanova E, Fedorov E, Aabakken L, Seitz U, Rey JF, Saurin JC, Tari R, Card T, Ragunath K (2020)
The use of rapid reading software to reduce capsule endoscopy reading times while maintaining accuracy
Gastrointest Endosc (in press)
DOI 10.1016/j.gie.2020.01.026, PubMed 31981645

Bjorlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his 50s with abdominal pain, itching and weight loss
Tidsskr. Nor. Laegeforen., 140 (3), 268-272

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his fifties with abdominal pain, itching and weight loss
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0390, PubMed 32105028

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
Rettelse: En mann i 50-årene med magesmerter, kløe og vekttap
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.20.0137, PubMed 32192268

Chandra A, Midtvedt K, Åsberg A, Eide IA (2020)
The Authors' Reply
Transplantation (in press)
DOI 10.1097/TP.0000000000003120, PubMed 31972700

Dahl KG, Andersen MH, Urstad KH, Falk RS, Engebretsen E, Wahl AK (2020)
Identifying Core Variables Associated With Health Literacy in Kidney Transplant Recipients
Prog Transplant, 30 (1), 38-47
DOI 10.1177/1526924819893285, PubMed 31918615

Dahle DO, Mjoen G (2020)
The Salutary Blood Pressure of a Solitary Kidney
Am J Hypertens, 33 (3), 218-219
DOI 10.1093/ajh/hpaa004, PubMed 31907513

Dueland S, Syversveen T, Solheim JM, Solberg S, Grut H, Bjørnbeth BA, Hagness M, Line PD (2020)
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg, 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404, PubMed 31188200

Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
Impact of Hiv-Related Gut Microbiota Alterations on Metabolic Comorbidities
Clin Infect Dis (in press)
DOI 10.1093/cid/ciz1235, PubMed 31894240

Gjerde A, Lillås BS, Marti HP, Reisæter AV, Vikse BE (2020)
Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life
Nephrol Dial Transplant (in press)
DOI 10.1093/ndt/gfaa001, PubMed 32040151

Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities
Hepatology (in press)
DOI 10.1002/hep.31110, PubMed 31925805

Golse N, Joly F, Nicolas Q, Vibert E, Line PD, Clementel IV (2020)
Partial orthotopic liver transplantation in combination with two-stage hepatectomy: A proof-of-concept explained by mathematical modeling
Clin Biomech (Bristol, Avon), 73, 195-200 (in press)
DOI 10.1016/j.clinbiomech.2020.01.020, PubMed 32035308

Haller MC, Wallisch C, Mjøen G, Holdaas H, Dunkler D, Heinze G, Oberbauer R (2020)
Predicting donor, recipient and graft survival in living donor kidney transplantation to inform pretransplant counselling: the donor and recipient linked iPREDICTLIVING tool - a retrospective study
Transpl Int
DOI 10.1111/tri.13580, PubMed 31970822

Hansen AMB, Wium C, Lee S, Tierney AC, McCarthy D, Roche HM, Drevon CA, Birkeland KI, Gulseth HL (2020)
Substantial inter-individual variations in insulin secretion and sensitivity across the glucometabolic spectrum
Scand J Clin Lab Invest
DOI 10.1080/00365513.2020.1730433, PubMed 32134347

Haugen AJ, Hallan S, Langberg NE, Dahle DO, Pihlstrøm H, Birkeland KI, Reisaeter A, Midtvedt K, Hartmann A, Holdaas H, Mjøen G (2020)
Increased long-term risk for hypertension in kidney donors - a retrospective cohort study
Transpl Int
DOI 10.1111/tri.13576, PubMed 31958170

Hibi T, Rela M, Eason J, Line PD, Fung J, Sakamoto S, Selzner N, Man NK, Ghobrial RM, Sapisochin G (2020)
Liver Transplantation for Colorectal and Neuroendocrine Liver Metastases and Hepatoblastoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference
Transplantation (in press)
DOI 10.1097/TP.0000000000003118, PubMed 32217939

Holmen H, Larsen MH, Sallinen MH, Thoresen L, Ahlsen B, Andersen MH, Borge CR, Eik H, Wahl AK, Mengshoel AM (2020)
Working with patients suffering from chronic diseases can be a balancing act for health care professionals - a meta-synthesis of qualitative studies
BMC Health Serv Res, 20 (1), 98
DOI 10.1186/s12913-019-4826-2, PubMed 32039723

Hugenschmidt H, Labori KJ, Brunborg C, Verbeke CS, Seeberg LT, Schirmer CB, Renolen A, Borgen EF, Naume B, Wiedswang G (2020)
Circulating Tumor Cells are an Independent Predictor of Shorter Survival in Patients Undergoing Resection for Pancreatic and Periampullary Adenocarcinoma
Ann Surg, 271 (3), 549-558
DOI 10.1097/SLA.0000000000003035, PubMed 30216219

Kalager M, Bretthauer M (2020)
Improving cancer screening programs
Science, 367 (6474), 143-144
DOI 10.1126/science.aay3156, PubMed 31919207

Klaasen RA, Bergan S, Bremer S, Hole K, Nordahl CB, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2020)
Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation
Br J Clin Pharmacol
DOI 10.1111/bcp.14218, PubMed 31925806

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Lapitz A, Arbelaiz A, O'Rourke CJ, Lavin JL, Casta A, Ibarra C, Jimeno JP, Santos-Laso A, Izquierdo-Sanchez L, Krawczyk M, Perugorria MJ, Jimenez-Aguero R, Sanchez-Campos A, Riaño I, Gónzalez E, Lammert F, Marzioni M, Macias RIR, Marin JJG, Karlsen TH, Bujanda L, Falcón-Pérez JM, Andersen JB, Aransay AM, Rodrigues PM et al. (2020)
Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
Cells, 9 (3)
DOI 10.3390/cells9030721, PubMed 32183400

Legøy TA, Ghila L, Vethe H, Abadpour S, Mathisen AF, Paulo JA, Scholz H, Raeder H, Chera S (2020)
In vivo hyperglycaemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress
Acta Physiol (Oxf), 228 (4), e13433
DOI 10.1111/apha.13433, PubMed 31872528

Legøy TA, Mathisen AF, Salim Z, Vethe H, Bjørlykke Y, Abadpour S, Paulo JA, Scholz H, Ræder H, Ghila L, Chera S (2020)
In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism
Front Cell Dev Biol, 8, 109
DOI 10.3389/fcell.2020.00109, PubMed 32161757

Legøy TA, Vethe H, Abadpour S, Strand BL, Scholz H, Paulo JA, Ræder H, Ghila L, Chera S (2020)
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Sci Rep, 10 (1), 414
DOI 10.1038/s41598-019-57305-x, PubMed 31942009

Lorentzen EM, Henriksen S, Kaur A, Kro GB, Hammarström C, Hirsch HH, Midtvedt K, Rinaldo CH (2020)
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Virol J, 17 (1), 5
DOI 10.1186/s12985-019-1275-9, PubMed 31924245

Lousdal ML, Lash TL, Flanders WD, Brookhart MA, Kristiansen IS, Kalager M, Støvring H (2020)
Negative controls to detect uncontrolled confounding in observational studies of mammographic screening comparing participants and non-participants
Int J Epidemiol (in press)
DOI 10.1093/ije/dyaa029, PubMed 32211885

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12596, PubMed 31978943

Mori Y, Kudo SE, East JE, Rastogi A, Bretthauer M, Misawa M, Sekiguchi M, Matsuda T, Saito Y, Ikematsu H, Hotta K, Ohtsuka K, Kudo T, Mori K (2020)
Cost savings in colonoscopy with artificial intelligence-aided polyp diagnosis: an add-on analysis of a clinical trial (with video)
Gastrointest Endosc (in press)
DOI 10.1016/j.gie.2020.03.3759, PubMed 32240683

Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L (2020)
Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study
Transplantation, 104 (1), 190-196
DOI 10.1097/TP.0000000000002777, PubMed 31365472

Nordheim E, Dahle DO, Halden T, Birkeland KI, Åsberg A, Hartmann A, Horneland R, Jenssen TG (2020)
Endothelial function after pancreas transplantation-A single-center observational study
Clin Transplant, 34 (3), e13815
DOI 10.1111/ctr.13815, PubMed 32027399

Pippias M, Jager KJ, Åsberg A, Berger SP, Finne P, Heaf JG, Kerschbaum J, Lempinen M, Magaz Á, Massy ZA, Stel VS (2020)
Young deceased donor kidneys show a survival benefit over older donor kidneys in transplant recipients aged 20-50 years: a study by the ERA-EDTA Registry
Nephrol Dial Transplant, 35 (3), 534-543
DOI 10.1093/ndt/gfy268, PubMed 30203080

Ting YT, Dahal-Koirala S, Kim HSK, Qiao SW, Neumann RS, Lundin KEA, Petersen J, Reid HH, Sollid LM, Rossjohn J (2020)
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305

Trimboli P, Castellana M, Virili C, Havre RF, Bini F, Marinozzi F, D'Ambrosio F, Giorgino F, Giovanella L, Prosch H, Grani G, Radzina M, Cantisani V (2020)
Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference
Radiol Med
DOI 10.1007/s11547-019-01129-2, PubMed 31970579

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Vesterhus M, Karlsen TH (2020)
Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
J Gastroenterol (in press)
DOI 10.1007/s00535-020-01681-z, PubMed 32222826

 
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