Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Cardiology (Div CPD)

36 publications found

Ajmone Marsan N, Michalski B, Cameli M, Podlesnikar T, Manka R, Sitges M, Dweck MR, Haugaa KH (2020)
EACVI survey on standardization of cardiac chambers quantification by transthoracic echocardiography
Eur Heart J Cardiovasc Imaging, 21 (2), 119-123
DOI 10.1093/ehjci/jez297, PubMed 31819943

Andersen ØS, Krogh MR, Boe E, Storsten P, Aalen JM, Larsen CK, Skulstad H, Odland HH, Smiseth OA, Remme EW (2020)
Left Bundle Branch Block Increases Left Ventricular Diastolic Pressure during Tachycardia due to Incomplete Relaxation
J Appl Physiol (1985) (in press)
DOI 10.1152/japplphysiol.01002.2018, PubMed 31999529

Bergh N, Gude E, Bartfay SE, K Andreassen A, Arora S, Dahlberg P, Dellgren G, Gullestad L, Gustafsson F, Karasson K, Rådegran G, Bollano E, Andersson B (2020)
Invasive haemodynamics in de novo everolimus vs. calcineurin inhibitor heart transplant recipients
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12608, PubMed 32059083

Duchenne J, Aalen JM, Cvijic M, Larsen CK, Galli E, Bézy S, Beela AS, Ünlü S, Pagourelias ED, Winter S, Hopp E, Kongsgård E, Donal E, Fehske W, Smiseth OA, Voigt JU (2020)
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa003, PubMed 32031587

Espinoza A, Kerans V, Bugge JF, Skulstad H, Halvorsen PS (2020)
Left Ventricular Function During Epinephrine Stimulation and Hypothermia: Effects at Spontaneous and Paced Heart Rates in a Porcine Model
Ther Hypothermia Temp Manag
DOI 10.1089/ther.2019.0035, PubMed 31916922

Gude E, Hoel TN, Sørensen G, Broch K, Meyer A, Fiane AE (2020)
Long-term continuous flow mechanical biventricular support: 9 years and counting
Interact Cardiovasc Thorac Surg, 30 (1), 81-84
DOI 10.1093/icvts/ivz231, PubMed 31580433

Gul KA, Strand J, Pettersen RD, Brun H, Abrahamsen TG (2020)
T-cell Receptor Excision Circles in Newborns with Heart Defects
Pediatr Cardiol (in press)
DOI 10.1007/s00246-020-02317-y, PubMed 32166410

Gustafsson F, Andreassen AK, Andersson B, Eiskjær H, Rådegran G, Gude E, Jansson K, Solbu D, Karason K, Arora S, Dellgren G, Gullestad L, SCHEDULE (Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance) Investigators* (2020)
Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Long-term Follow-up From the Randomized SCHEDULE Study
Transplantation, 104 (1), 154-164
DOI 10.1097/TP.0000000000002702, PubMed 30893292

Klaeboe LG, Brekke PH, Aaberge L, Haugaa K, Edvardsen T (2020)
Impact of transcatheter aortic valve implantation on mechanical dispersion
Open Heart, 7 (1), e001199
DOI 10.1136/openhrt-2019-001199, PubMed 32153792

Kleiven Ø, Bjørkavoll-Bergseth MF, Omland T, Aakre KM, Frøysa V, Erevik CB, Greve OJ, Melberg TH, Auestad B, Skadberg Ø, Edvardsen T, Ørn S (2020)
Endurance exercise training volume is not associated with progression of coronary artery calcification
Scand J Med Sci Sports (in press)
DOI 10.1111/sms.13643, PubMed 32100340

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ et al. (2020)
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Eur Heart J, 41 (3), 407-477
DOI 10.1093/eurheartj/ehz425, PubMed 31504439

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Langseth MS, Helseth R, Ritschel V, Hansen CH, Andersen GØ, Eritsland J, Halvorsen S, Fagerland MW, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2020)
Double-Stranded DNA and NETs Components in Relation to Clinical Outcome After ST-Elevation Myocardial Infarction
Sci Rep, 10 (1), 5007
DOI 10.1038/s41598-020-61971-7, PubMed 32193509

Larsen CK, Aalen JM, Stokke C, Fjeld JG, Kongsgaard E, Duchenne J, Degtiarova G, Gheysens O, Voigt JU, Smiseth OA, Hopp E (2020)
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231, PubMed 31599327

Lieve KVV, Dusi V, van der Werf C, Bos JM, Lane CM, Stokke MK, Roston TM, Djupsjöbacka A, Wada Y, Denjoy I, Bundgaard H, Noguer FRI, Semsarian C, Robyns T, Hofman N, Tanck MW, van den Berg MP, Kammeraad JAE, Krahn AD, Clur SB, Sacher F, Till J, Skinner JR, Tfelt-Hansen J, Probst V et al. (2020)
Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia
Circ Arrhythm Electrophysiol, 13 (3), e007471
DOI 10.1161/CIRCEP.119.007471, PubMed 32063070

Magne J, Bharucha T, Cikes M, Galderisi M, Price S, Sade LE, Popescu BA, Cosyns B, Edvardsen T (2020)
EuroEcho 2019: highlights
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa037, PubMed 32182333

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail (in press)
DOI 10.1002/ehf2.12596, PubMed 31978943

Michalski B, Dweck MR, Marsan NA, Cameli M, D'Andrea A, Carvalho RF, Holte E, Robert TP, Haugaa KH (2020)
The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: a survey by EACVI
Eur Heart J Cardiovasc Imaging, 21 (4), 357-362
DOI 10.1093/ehjci/jeaa009, PubMed 32196100

Muthiah A, Beitnes JO, Skulstad H (2020)
Patients with infective endocarditis referred to Division of Cardiovascular and Pulmonary Diseases at Oslo University Hospital between 2014 and 2017
Scand Cardiovasc J
DOI 10.1080/14017431.2020.1734232, PubMed 32157906

Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation (in press)
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258

Nelson LM, Andreassen AK, Arora S, Andersson B, Gude E, Eiskjaer H, Rådegran G, Dellgren G, Gullestad L, Gustafsson F (2020)
Mild acute cellular rejection and development of cardiac allograft vasculopathy assessed by intravascular ultrasound and coronary angiography in heart transplant recipients-a SCHEDULE trial substudy
Transpl Int
DOI 10.1111/tri.13577, PubMed 31958178

Norekvål TM, Allore HG, Bendz B, Bjorvatn C, Borregaard B, Brørs G, Deaton C, Fålun N, Hadjistavropoulos H, Hansen TB, Igland S, Larsen AI, Palm P, Pettersen TR, Rasmussen TB, Schjøtt J, Søgaard R, Valaker I, Zwisler AD, Rotevatn S, CONCARD Investigators (2020)
Rethinking rehabilitation after percutaneous coronary intervention: a protocol of a multicentre cohort study on continuity of care, health literacy, adherence and costs at all care levels (the CONCARDPCI)
BMJ Open, 10 (2), e031995
DOI 10.1136/bmjopen-2019-031995, PubMed 32054625

Peersen K, Otterstad JE, Sverre E, Perk J, Gullestad L, Moum T, Dammen T, Munkhaugen J (2020)
Medical and Psychosocial Factors Associated With Low Physical Activity and Increasing Exercise Level After a Coronary Event
J Cardiopulm Rehabil Prev, 40 (1), 35-40
DOI 10.1097/HCR.0000000000000399, PubMed 30720643

Pezel T, Coisne A, Mahmoud-Elsayed H, Mandoli GE, Elgamal SM, Podlesnikar T, Cameli M, Grapsa J, Lafitte S, Edvardsen T, Donal E, Dreyfus J (2020)
EACVI communication paper: first international young dedicated multimodal cardiovascular imaging simulation education event organized by the ESC
Eur Heart J Cardiovasc Imaging, 21 (2), 124-126
DOI 10.1093/ehjci/jez299, PubMed 31834376

Rodriguez-Palomares JF, Edvardsen T, Almeida AG, Petersen SE (2020)
EuroCMR 2019 highlights
Eur Heart J Cardiovasc Imaging, 21 (2), 127-131
DOI 10.1093/ehjci/jez307, PubMed 31821461

Ross S, Nestaas E, Kongsgaard E, Odland HH, Haland TF, Hopp E, Haugaa KH, Edvardsen T (2020)
Septal contraction predicts acute haemodynamic improvement and paced QRS width reduction in cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jez315, PubMed 31925420

Rutherford OW, Jonasson C, Ghanima W, Söderdahl F, Halvorsen S (2020)
Comparison of dabigatran, rivaroxaban, and apixaban for effectiveness and safety in atrial fibrillation: a nationwide cohort study
Eur Heart J Cardiovasc Pharmacother, 6 (2), 75-85
DOI 10.1093/ehjcvp/pvz086, PubMed 31942972

Schalit I, Espinoza A, Pettersen FJ, Snartland S, Ringdal ML, Hoel TN, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2020)
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J, 66 (1), 38-48
DOI 10.1097/MAT.0000000000000954, PubMed 30688692

Skattebo Ø, Bjerring AW, Auensen M, Sarvari SI, Cumming KT, Capelli C, Hallén J (2020)
Blood volume expansion does not explain the increase in peak oxygen uptake induced by 10 weeks of endurance training
Eur J Appl Physiol (in press)
DOI 10.1007/s00421-020-04336-2, PubMed 32172291

Skjølsvik ET, Hasselberg NE, Dejgaard LA, Lie ØH, Andersen K, Holm T, Edvardsen T, Haugaa KH (2020)
Exercise is Associated With Impaired Left Ventricular Systolic Function in Patients With Lamin A/C Genotype
J Am Heart Assoc, 9 (2), e012937
DOI 10.1161/JAHA.119.012937, PubMed 31957533

Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc Res, 116 (1), 78-90
DOI 10.1093/cvr/cvz087, PubMed 30949686

Smiseth OA, Inoue K (2020)
The left atrium: a mirror of ventricular systolic and diastolic function
Eur Heart J Cardiovasc Imaging, 21 (3), 270-272
DOI 10.1093/ehjci/jez305, PubMed 31840753

Smistad E, Bernard O, Grenne B, Lovstakken L, Ostvik A, Salte IM, Melichova D, Nguyen TM, Haugaa K, Brunvand H, Edvardsen T, Leclerc S (2020)
Real-time automatic ejection fraction and foreshortening detection using deep learning
IEEE Trans Ultrason Ferroelectr Freq Control (in press)
DOI 10.1109/TUFFC.2020.2981037, PubMed 32175861

Storsten P, Aalen JM, Boe E, Remme EW, Gjesdal O, Larsen CK, Andersen ØS, Eriksen M, Kongsgaard E, Duchenne J, Voigt JU, Smiseth OA, Skulstad H (2020)
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2019.11.016, PubMed 31954643

Sverre E, Peersen K, Weedon-Fekjær H, Perk J, Gjertsen E, Husebye E, Gullestad L, Dammen T, Otterstad JE, Munkhaugen J (2020)
Preventable clinical and psychosocial factors predicted two out of three recurrent cardiovascular events in a coronary population
BMC Cardiovasc Disord, 20 (1), 61
DOI 10.1186/s12872-020-01368-6, PubMed 32024471

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

 
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