Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Institute for Surgical Research ISR

32 publications found

Babić A, Odland HH, Lyseggen E, Holm T, Ross S, Hopp E, Haugaa KH, Kongsgård E, Edvardsen T, Gérard O, Samset E (2019)
An image fusion tool for echo-guided left ventricular lead placement in cardiac resynchronization therapy: Performance and workflow integration analysis
Echocardiography, 36 (10), 1834-1845
DOI 10.1111/echo.14483, PubMed 31628770

Bergström M, Müller M, Karlsson M, Scholz H, Vethe NT, Korsgren O (2019)
Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
Cell Transplant, UNSP 0963689719872488
DOI 10.1177/0963689719872488, PubMed 31512504

Boe E, Smiseth OA, Storsten P, Andersen OS, Aalen J, Eriksen M, Krogh MR, Kongsgaard E, Remme EW, Skulstad H (2019)
Left ventricular end-systolic volume is a more sensitive marker of acute response to cardiac resynchronization therapy than contractility indices: insights from an experimental study
Europace, 21 (2), 347-355
DOI 10.1093/europace/euy221, PubMed 30418572

Castrini AI, Lie ØH, Leren IS, Estensen ME, Stokke MK, Klæboe LG, Edvardsen T, Haugaa KH (2019)
Number of pregnancies and subsequent phenotype in a cross-sectional cohort of women with arrhythmogenic cardiomyopathy
Eur Heart J Cardiovasc Imaging, 20 (2), 192-198
DOI 10.1093/ehjci/jey061, PubMed 29659777

Galli E, Hubert A, Le Rolle V, Hernandez A, Smiseth OA, Mabo P, Leclercq C, Donal E (2019)
Myocardial constructive work and cardiac mortality in resynchronization therapy candidates
Am Heart J, 212, 53-63
DOI 10.1016/j.ahj.2019.02.008, PubMed 30951976

Haugaa KH, Leren IS (2019)
Prevalence, Clinical Presentation, and Management of Channelopathies and Cardiomyopathies, Long QT Syndrome, Brugada Syndrome, Arrhythmogenic Cardiomyopathy, and Hypertrophic Cardiomyopathy
Curr. Cardiovascu. Risk Rep., 13 (7), 16

Hjorthaug GA, Søreide E, Nordsletten L, Madsen JE, Reinholt FP, Niratisairak S, Dimmen S (2019)
Short-term perioperative parecoxib is not detrimental to shaft fracture healing in a rat model
Bone Joint Res, 8 (10), 472-480
DOI 10.1302/2046-3758.810.BJR-2018-0341.R1, PubMed 31728186

Hvinden IC, Berg HE, Sachse D, Skaga E, Skottvoll FS, Lundanes E, Sandberg CJ, Vik-Mo EO, Rise F, Wilson SR (2019)
Nuclear Magnetic Resonance Spectroscopy to Identify Metabolite Biomarkers of Nonresponsiveness to Targeted Therapy in Glioblastoma Tumor Stem Cells
J Proteome Res, 18 (5), 2012-2020
DOI 10.1021/acs.jproteome.8b00801, PubMed 30964684

Impieri D, Tønseth KA, Hide Ø, Feragen KJB, Høgevold HE, Filip C (2019)
Autologous fat transplantation to the velopharynx for treating mild velopharyngeal insufficiency: A 10-year experience
J Plast Reconstr Aesthet Surg, 72 (8), 1403-1410
DOI 10.1016/j.bjps.2019.03.040, PubMed 31103609

Jackson CJ, Myklebust Ernø IT, Ringstad H, Tønseth KA, Dartt DA, Utheim TP (2019)
Simple limbal epithelial transplantation: Current status and future perspectives: Concise review
Stem Cells Transl Med (in press)
DOI 10.1002/sctm.19-0203, PubMed 31802651

Karlsen S, Dahlslett T, Grenne B, Sjøli B, Smiseth O, Edvardsen T, Brunvand H (2019)
Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training
Cardiovasc Ultrasound, 17 (1), 18
DOI 10.1186/s12947-019-0168-9, PubMed 31477137

Kawakami H, Nerlekar N, Haugaa KH, Edvardsen T, Marwick TH (2019)
Prediction of Ventricular Arrhythmias With Left Ventricular Mechanical Dispersion: A Systematic Review and Meta-Analysis
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2019.03.025, PubMed 31202762

Kjeldsen SE, von Lueder TG, Smiseth OA, Wachtell K, Mistry N, Westheim AS, Hopper I, Julius S, Pitt B, Reid CM, Devereux RB, Zannad F (2019)
Medical Therapies for Heart Failure With Preserved Ejection Fraction
Hypertension, 75 (1), 23-32
DOI 10.1161/HYPERTENSIONAHA.119.14057, PubMed 31786973

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ et al. (2019)
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehz425, PubMed 31504439

Krogh MR, Halvorsen PS, Elle OJ, Bergsland J, Remme EW (2019)
Dynamic gravity compensation does not increase detection of myocardial ischemia in combined accelerometer and gyro sensor measurements
Sci Rep, 9 (1), 2671
DOI 10.1038/s41598-018-35630-x, PubMed 30804438

Kvale KF, Bersvendsen J, Remme EW, Salles S, Aalen JM, Brekke PH, Edvardsen T, Samset E (2019)
Detection of Regional Mechanical Activation of the Left Ventricular Myocardium Using High Frame Rate Ultrasound Imaging
IEEE Trans Med Imaging, 38 (11), 2665-2675
DOI 10.1109/TMI.2019.2909358, PubMed 30969919

Larsen CK, Aalen JM, Stokke C, Fjeld JG, Kongsgaard E, Duchenne J, Degtiarova G, Gheysens O, Voigt JU, Smiseth OA, Hopp E (2019)
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jez231, PubMed 31599327

Melau J, Bonnevie-Svendsen M, Mathiassen M, Mykland Hilde J, Oma L, Hisdal J (2019)
Late-Presenting Swimming-Induced Pulmonary Edema: A Case Report Series from the Norseman Xtreme Triathlon
Sports (Basel), 7 (6)
DOI 10.3390/sports7060137, PubMed 31163677

Nguyen TT, Espinoza AW, Hyler S, Remme EW, D'hooge J, Hoff L (2019)
Estimating Regional Myocardial Contraction Using Miniature Transducers on the Epicardium
Ultrasound Med Biol, 45 (11), 2958-2969
DOI 10.1016/j.ultrasmedbio.2019.07.416, PubMed 31447239

Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW (2019)
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004

Rodriguez-Palomares JF, Edvardsen T, Almeida AG, Petersen SE (2019)
EuroCMR 2019 highlights
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jez307, PubMed 31821461

Saraste A, Barbato E, Capodanno D, Edvardsen T, Prescott E, Achenbach S, Bax JJ, Wijns W, Knuuti J (2019)
Imaging in ESC clinical guidelines: chronic coronary syndromes
Eur Heart J Cardiovasc Imaging, 20 (11), 1187-1197
DOI 10.1093/ehjci/jez219, PubMed 31642920

Shi JH, Guo WZ, Jin Y, Zhang HP, Pang C, Li J, Line PD, Zhang SJ (2019)
Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence
Cancer Med, 8 (3), 1269-1278
DOI 10.1002/cam4.2006, PubMed 30714677

Skaga E, Kulesskiy E, Fayzullin A, Sandberg CJ, Potdar S, Kyttälä A, Langmoen IA, Laakso A, Gaál-Paavola E, Perola M, Wennerberg K, Vik-Mo EO (2019)
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naïve glioblastoma
BMC Cancer, 19 (1), 628
DOI 10.1186/s12885-019-5861-4, PubMed 31238897

Skaga E, Skaga IØ, Grieg Z, Sandberg CJ, Langmoen IA, Vik-Mo EO (2019)
The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy
J Cancer Res Clin Oncol, 145 (6), 1495-1507
DOI 10.1007/s00432-019-02920-4, PubMed 31028540

Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA (2019)
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
J Plast Surg Hand Surg, 53 (2), 119-124
DOI 10.1080/2000656X.2018.1562459, PubMed 30654667

Smiseth OA, Kjeldsen SE, Andersen OS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Heart Failure with normal ejection fraction
Tidsskr. Nor. Laegeforen., 139 (6), 522-527

Smiseth OA, Kjeldsen SE, Andersen ØS, Mistry N, Westheim AS, Skulstad H, Gude E (2019)
Heart failure with preserved ejection fraction
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0523, PubMed 30917641

Stensrud MJ, Aalen JM, Aalen OO, Valberg M (2019)
Limitations of hazard ratios in clinical trials
Eur Heart J, 40 (17), 1378-1383
DOI 10.1093/eurheartj/ehy770, PubMed 30500891

Weldingh E, Johnsen MB, Hagen KB, Østerås N, Risberg MA, Natvig B, Slatkowsky-Christensen B, Fenstad AM, Furnes O, Nordsletten L, Magnusson K (2019)
The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis
Arthritis Rheumatol, 71 (11), 1844-1848
DOI 10.1002/art.41023, PubMed 31237417

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Aalen JM, Remme EW, Larsen CK, Andersen OS, Krogh M, Duchenne J, Hopp E, Ross S, Beela AS, Kongsgaard E, Bergsland J, Odland HH, Skulstad H, Opdahl A, Voigt JU, Smiseth OA (2019)
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging, 12 (12), 2402-2413
DOI 10.1016/j.jcmg.2018.11.030, PubMed 30772230

 
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