Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Institute for Cancer Research

155 publications found

Abravan A, Eide HA, Løndalen AM, Helland Å, Malinen E (2018)
Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer
Mol Imaging Biol (in press)
DOI 10.1007/s11307-018-1226-7, PubMed 29916117

Andersen E, Chollet ME, Myklebust CF, Pinotti M, Bernardi F, Chuansumrit A, Skarpen E, Sandset PM, Skretting G (2018)
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
Thromb Haemost, 118 (4), 664-675
DOI 10.1055/s-0038-1637690, PubMed 29618153

Aqrawi LA, Jensen JL, Øijordsbakken G, Ruus AK, Nygård S, Holden M, Jonsson R, Galtung HK, Skarstein K (2018)
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development
Autoimmunity, 51 (3), 135-146
DOI 10.1080/08916934.2018.1446525, PubMed 29504848

Aurtenetxe O, Zaldumbide L, Erramuzpe A, López R, López JI, Cortés JM, Pulido R, Nunes-Xavier CE (2018)
DUSP5 expression associates with poor prognosis in human neuroblastoma
Exp Mol Pathol, 105 (3), 272-278 (in press)
DOI 10.1016/j.yexmp.2018.08.008, PubMed 30171833

Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å (2018)
Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
BMC Cancer, 18 (1), 739
DOI 10.1186/s12885-018-4659-0, PubMed 30005623

Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
Patterns of genomic evolution in advanced melanoma
Nat Commun, 9 (1), 2665
DOI 10.1038/s41467-018-05063-1, PubMed 29991680

Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ (2018)
Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
Clin Cancer Res, 24 (8), 1834-1844
DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931

Bousquet PA, Meltzer S, Sønstevold L, Esbensen Y, Dueland S, Flatmark K, Sitter B, Bathen TF, Seierstad T, Redalen KR, Eide L, Ree AH (2018)
Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
Transl Oncol, 12 (1), 76-83 (in press)
DOI 10.1016/j.tranon.2018.09.010, PubMed 30273860

Boye K, Berner JM, Hompland I, Bruland ØS, Stoldt S, Sundby Hall K, Bjerkehagen B, Hølmebakk T (2018)
Genotype and risk of tumour rupture in gastrointestinal stromal tumour
Br J Surg, 105 (2), e169-e175
DOI 10.1002/bjs.10743, PubMed 29341147

Briem E, Budkova Z, Sigurdardottir AK, Hilmarsdottir B, Kricker J, Timp W, Magnusson MK, Traustadottir GA, Gudjonsson T (2018)
MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin
Mech Dev (in press)
DOI 10.1016/j.mod.2018.11.002, PubMed 30508578

Bruun J, Sveen A, Barros R, Eide PW, Eilertsen I, Kolberg M, Pellinen T, David L, Svindland A, Kallioniemi O, Guren MG, Nesbakken A, Almeida R, Lothe RA (2018)
Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
Mol Oncol, 12 (9), 1639-1655
DOI 10.1002/1878-0261.12347, PubMed 29900672

Brynildsen J, Petäjä L, Pettilä V, Nygård S, Vaara ST, Linko R, Okkonen M, Hagve TA, Soininen L, Suojaranta-Ylinen R, Lyngbakken MN, Omland T, Røsjø H (2018)
The predictive value of NT-proBNP and hs-TnT for risk of death in cardiac surgical patients
Clin Biochem, 53, 65-71
DOI 10.1016/j.clinbiochem.2018.01.012, PubMed 29371002

Bråte J, Neumann RS, Fromm B, Haraldsen AAB, Tarver JE, Suga H, Donoghue PCJ, Peterson KJ, Ruiz-Trillo I, Grini PE, Shalchian-Tabrizi K (2018)
Unicellular Origin of the Animal MicroRNA Machinery
Curr Biol, 28 (20), 3288-3295.e5
DOI 10.1016/j.cub.2018.08.018, PubMed 30318349

Bøe CA, Håland TW, Boye E, Syljuåsen RG, Grallert B (2018)
A novel role for ATR/Rad3 in G1 phase
Sci Rep, 8 (1), 6880
DOI 10.1038/s41598-018-25238-6, PubMed 29720710

Celestino R, Nome T, Pestana A, Hoff AM, Gonçalves AP, Pereira L, Cavadas B, Eloy C, Bjøro T, Sobrinho-Simões M, Skotheim RI, Soares P (2018)
CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension
BMC Cancer, 18 (1), 68
DOI 10.1186/s12885-017-3948-3, PubMed 29321030

Chèneby J, Gheorghe M, Artufel M, Mathelier A, Ballester B (2018)
ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments
Nucleic Acids Res, 46 (D1), D267-D275
DOI 10.1093/nar/gkx1092, PubMed 29126285

Clayton A, Buschmann D, Byrd JB, Carter DRF, Cheng L, Compton C, Daaboul G, Devitt A, Falcon-Perez JM, Gardiner C, Gustafson D, Harrison P, Helmbrecht C, Hendrix A, Hill A, Hoffman A, Jones JC, Kalluri R, Kang JY, Kirchner B, Lasser C, Lawson C, Lenassi M, Levin C, Llorente A et al. (2018)
Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017
J. Extracell. Vesicles, 7 (1), 1473707

Danielsen HE, Hveem TS, Domingo E, Pradhan M, Kleppe A, Syvertsen RA, Kostolomov I, Nesheim JA, Askautrud HA, Nesbakken A, Lothe RA, Svindland A, Shepherd N, Novelli M, Johnstone E, Tomlinson I, Kerr R, Kerr DJ (2018)
Prognostic markers for colorectal cancer: estimating ploidy and stroma
Ann Oncol, 29 (3), 616-623
DOI 10.1093/annonc/mdx794, PubMed 29293881

De Santis F, Del Vecchio M, Castagnoli L, De Braud F, Di Cosimo S, Franceschini D, Fucà G, Hiscott J, Malmberg KJ, McGranahan N, Pietrantonio F, Rivoltini L, Sangaletti S, Tagliabue E, Tripodo C, Vernieri C, Zitvogel L, Pupa SM, Di Nicola M (2018)
Innovative therapy, monoclonal antibodies, and beyond: Highlights from the eighth annual meeting
Cytokine Growth Factor Rev (in press)
DOI 10.1016/j.cytogfr.2018.10.005, PubMed 30393044

Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
Hered Cancer Clin Pract, 16, 4
DOI 10.1186/s13053-018-0086-0, PubMed 29371908

Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
Identification of genetic variants for clinical management of familial colorectal tumors
BMC Med Genet, 19 (1), 26
DOI 10.1186/s12881-018-0533-9, PubMed 29458332

Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
Fam Cancer, 17 (1), 141-153
DOI 10.1007/s10689-017-0011-0, PubMed 28608266

Ebenesersdóttir SS, Sandoval-Velasco M, Gunnarsdóttir ED, Jagadeesan A, Guðmundsdóttir VB, Thordardóttir EL, Einarsdóttir MS, Moore KHS, Sigurðsson Á, Magnúsdóttir DN, Jónsson H, Snorradóttir S, Hovig E, Møller P, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Cavalleri GL, Gilbert E, Lalueza-Fox C, Walser JW, Kristjánsdóttir S, Gopalakrishnan S et al. (2018)
Ancient genomes from Iceland reveal the making of a human population
Science, 360 (6392), 1028-1032
DOI 10.1126/science.aar2625, PubMed 29853688

Eide HA, Knudtsen IS, Sandhu V, Løndalen AM, Halvorsen AR, Abravan A, Kure EH, Bogsrud TV, Brustugun OT, Kyte JA, Malinen E, Helland Å (2018)
Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
Adv Radiat Oncol, 3 (2), 130-138
DOI 10.1016/j.adro.2017.12.007, PubMed 29904737

Eide PW, Eilertsen IA, Sveen A, Lothe RA (2018)
Long non-coding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell-intrinsic properties
Int J Cancer (in press)
DOI 10.1002/ijc.31998, PubMed 30447009

Eilertsen IA, Sveen A, Strømme JM, Skotheim RI, Nesbakken A, Lothe RA (2018)
Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
Int J Cancer (in press)
DOI 10.1002/ijc.31809, PubMed 30121958

Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochem Photobiol Sci, 17 (5), 539-551
DOI 10.1039/C7PP00358G, PubMed 29565434

Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P (2018)
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
Sci Signal, 11 (548)
DOI 10.1126/scisignal.aap8608, PubMed 30228226

Fenaroli F, Repnik U, Xu Y, Johann K, Van Herck S, Dey P, Skjeldal FM, Frei DM, Bagherifam S, Kocere A, Haag R, De Geest BG, Barz M, Russell DG, Griffiths G (2018)
Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models
ACS Nano, 12 (8), 8646-8661
DOI 10.1021/acsnano.8b04433, PubMed 30081622

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937

Gandara DR, von Pawel J, Mazieres J, Sullivan R, Helland Å, Han JY, Ponce Aix S, Rittmeyer A, Barlesi F, Kubo T, Park K, Goldschmidt J, Gandhi M, Yun C, Yu W, Matheny C, He P, Sandler A, Ballinger M, Fehrenbacher L (2018)
Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study
J Thorac Oncol, 13 (12), 1906-1918
DOI 10.1016/j.jtho.2018.08.2027, PubMed 30217492

Gheorghe M, Sandve GK, Khan A, Chèneby J, Ballester B, Mathelier A (2018)
A map of direct TF-DNA interactions in the human genome
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky1210, PubMed 30517703

Glodzik D, Purdie C, Rye IH, Simpson P, Staaf J, Span PN, Russnes H, Nik-Zainal S (2018)
Mutational mechanisms of amplifications revealed by analysis of clustered rearrangements in breast cancers
Ann Oncol (in press)
DOI 10.1093/annonc/mdy404, PubMed 30252041

González ML, Causada-Calo N, Santino JP, Dominguez-Valentin M, Ferro FA, Sammartino I, Kalfayan PG, Verzura MA, Piñero TA, Cajal AR, Pavicic W, Vaccaro C (2018)
Universal determination of microsatellite instability using BAT26 as a single marker in an Argentine colorectal cancer cohort
Fam Cancer, 17 (3), 395-402
DOI 10.1007/s10689-017-0052-4, PubMed 29128931

Gouravan S, Meza-Zepeda LA, Myklebost O, Stratford EW, Munthe E (2018)
Preclinical Evaluation of Vemurafenib as Therapy for BRAFV600E Mutated Sarcomas
Int J Mol Sci, 19 (4)
DOI 10.3390/ijms19040969, PubMed 29570692

Guo Y, Zhang R, Shen S, Wei Y, Salama SM, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Su L, Zhu Z, Staaf J, Helland Å, Esteller M, Christiani DC (2018)
DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients
Cancer Epidemiol Biomarkers Prev, 27 (12), 1527-1535
DOI 10.1158/1055-9965.EPI-18-0454, PubMed 30185536

Halvorsen AR, Sandhu V, Sprauten M, Flote VG, Kure EH, Brustugun OT, Helland Å (2018)
Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab
Acta Oncol, 57 (9), 1225-1231
DOI 10.1080/0284186X.2018.1465585, PubMed 29683761

Haug M, Brede G, Håkerud M, Nedberg AG, Gederaas OA, Flo TH, Edwards VT, Selbo PK, Høgset A, Halaas Ø (2018)
Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination
Front Immunol, 9, 650
DOI 10.3389/fimmu.2018.00650, PubMed 29670624

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK (2018)
Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy
Transl Oncol, 11 (5), 1128-1136
DOI 10.1016/j.tranon.2018.07.005, PubMed 30036782

Hermansen JU, Tjønnfjord GE, Munthe LA, Taskén K, Skånland SS (2018)
Cryopreservation of primary B cells minimally influences their signaling responses
Sci Rep, 8 (1), 17651
DOI 10.1038/s41598-018-36121-9, PubMed 30518828

Herrera M, Llorens C, Rodríguez M, Herrera A, Ramos R, Gil B, Candia A, Larriba MJ, Garre P, Earl J, Rodríguez-Garrote M, Caldés T, Bonilla F, Carrato A, García-Barberán V, Peña C (2018)
Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer
Mol Cancer, 17 (1), 114
DOI 10.1186/s12943-018-0863-4, PubMed 30075793

Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky1102, PubMed 30395271

Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky846, PubMed 30247619

Hirschberg H, Berg K, Peng Q (2018)
Photodynamic therapy mediated immune therapy of brain tumors
Neuroimmunol Neuroinflamm, 5
DOI 10.20517/2347-8659.2018.31, PubMed 30221185

Holte H, Beiske K, Boyle M, Trøen G, Blaker YN, Myklebust J, Kvaløy S, Rosenwald A, Lingjaerde OC, Rimsza LM, Smeland EB, Scott DW, Kolstad A (2018)
The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy
Br J Haematol, 183 (2), 225-234
DOI 10.1111/bjh.15518, PubMed 30080252

Hompland I, Hølmebakk T, Boye K, Stoldt S, Bjerkehagen B, Berner JM, Wiedswang AM, Revheim ME, Poulsen JP, Hall KS, Bruland ØS (2018)
Multimodal kreftbehandling av gastrointestinal stromal tumor
Tidsskr Nor Laegeforen, 138 (15)
DOI 10.4045/tidsskr.18.0200, PubMed 30277049

Hompland T, Hole KH, Ragnum HB, Aarnes EK, Vlatkovic L, Lie AK, Patzke S, Brennhovd B, Seierstad T, Lyng H (2018)
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958

Hornshøj H, Nielsen MM, Sinnott-Armstrong NA, Świtnicki MP, Juul M, Madsen T, Sallari R, Kellis M, Ørntoft T, Hobolth A, Pedersen JS (2018)
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival
NPJ Genom Med, 3, 1
DOI 10.1038/s41525-017-0040-5, PubMed 29354286

Huang R, Rofstad EK (2018)
Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
J Exp Clin Cancer Res, 37 (1), 92
DOI 10.1186/s13046-018-0763-x, PubMed 29703238

Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL (2018)
Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Ecotoxicol Environ Saf, 154, 19-26
DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161

Höglander EK, Nord S, Wedge DC, Lingjærde OC, Silwal-Pandit L, Gythfeldt HV, Vollan HKM, Fleischer T, Krohn M, Schlitchting E, Borgen E, Garred Ø, Holmen MM, Wist E, Naume B, Van Loo P, Børresen-Dale AL, Engebraaten O, Kristensen V (2018)
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
Genome Med, 10 (1), 92
DOI 10.1186/s13073-018-0601-y, PubMed 30497530

Høland M, Kolberg M, Danielsen SA, Bjerkehagen B, Eilertsen IA, Hektoen M, Mandahl N, van den Berg E, Smeland S, Mertens F, Sundby Hall K, Picci P, Sveen A, Lothe RA (2018)
Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53
Mod Pathol, 31 (11), 1694-1707
DOI 10.1038/s41379-018-0074-y, PubMed 29946184

Ibrahim I, Dominguez-Valentin M, Segal B, Zeitouni A, da Silva SD (2018)
Mitochondrial mutations associated with hearing and balance disorders
Mutat Res, 810, 39-44
DOI 10.1016/j.mrfmmm.2018.03.003, PubMed 29615272

Ihle-Hansen H, Vigen T, Ihle-Hansen H, Rønning OM, Berge T, Thommessen B, Lyngbakken MN, Orstad EB, Enger S, Nygård S, Røsjø H, Tveit A (2018)
Prevalence of Carotid Plaque in a 63- to 65-Year-Old Norwegian Cohort From the General Population: The ACE (Akershus Cardiac Examination) 1950 Study
J Am Heart Assoc, 7 (10)
DOI 10.1161/JAHA.118.008562, PubMed 29739796

Jabeen S, Zucknick M, Nome M, Dannenfelser R, Fleischer T, Kumar S, Lüders T, von der Lippe Gythfeldt H, Troyanskaya O, Kyte JA, Børresen-Dale AL, Naume B, Tekpli X, Engebraaten O, Kristensen V (2018)
Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab
Oncoimmunology, 7 (11), e1457598
DOI 10.1080/2162402X.2018.1457598, PubMed 30377556

Juzeniene A, Bernoulli J, Suominen M, Halleen J, Larsen RH (2018)
Antitumor Activity of Novel Bone-seeking, α-emitting 224Ra-solution in a Breast Cancer Skeletal Metastases Model
Anticancer Res, 38 (4), 1947-1955
DOI 10.21873/anticanres.12432, PubMed 29599310

Kalanxhi E, Meltzer S, Schou JV, Larsen FO, Dueland S, Flatmark K, Jensen BV, Hole KH, Seierstad T, Redalen KR, Nielsen DL, Ree AH (2018)
Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
Br J Cancer, 118 (10), 1322-1328
DOI 10.1038/s41416-018-0085-y, PubMed 29695770

Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2018)
Colocalization analyses of genomic elements: approaches, recommendations and challenges
Bioinformatics (in press)
DOI 10.1093/bioinformatics/bty835, PubMed 30307532

Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Chèneby J, Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2018)
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
Nucleic Acids Res, 46 (D1), D260-D266
DOI 10.1093/nar/gkx1126, PubMed 29140473

Khan A, Mathelier A (2018)
JASPAR RESTful API: accessing JASPAR data from any programming language
Bioinformatics, 34 (9), 1612-1614
DOI 10.1093/bioinformatics/btx804, PubMed 29253085

Khan A, Mathelier A, Zhang X (2018)
Super-enhancers are transcriptionally more active and cell type-specific than stretch enhancers
Epigenetics, 13 (9), 910-922
DOI 10.1080/15592294.2018.1514231, PubMed 30169995

Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J, Hereditary Breast Cancer Clinical Study Group (2018)
Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
Int J Epidemiol, 47 (3), 987-997
DOI 10.1093/ije/dyy039, PubMed 29547931

Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290

Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M (2018)
Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
J Mol Biol, 430 (21), 4087-4101
DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027

Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2018)
Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
Gynecol Oncol, 150 (1), 85-91
DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803

Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2018)
Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
JAMA Oncol, 4 (8), 1059-1065
DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224

Kresse SH, Namløs HM, Lorenz S, Berner JM, Myklebost O, Bjerkehagen B, Meza-Zepeda LA (2018)
Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples
PLoS One, 13 (5), e0197456
DOI 10.1371/journal.pone.0197456, PubMed 29771965

Kruitwagen T, Chymkowitch P, Denoth-Lippuner A, Enserink J, Barral Y (2018)
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
Cell, 175 (3), 780-795.e15
DOI 10.1016/j.cell.2018.09.012, PubMed 30318142

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