Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Pediatric Research

31 publications found

Albatat M, Bergsland J, Arevalo H, Odland HH, Bose P, Halvorsen PS, Balasingham I (2019)
Technological and Clinical Challenges in Lead Placement for Cardiac Rhythm Management Devices
Ann Biomed Eng
DOI 10.1007/s10439-019-02376-0, PubMed 31576502

Aria S, Elfarri Y, Elvegård M, Gottfridsson A, Grønaas HS, Harang S, Jansen A, Madland TER, Martins IB, Olstad MW, Ryan TL, Shaban AN, Svenningsen ØL, Sørensen AD, Ulvestad EH, Vister OM, Øvergaard MB, Kalvøy H, Pettersen FJ, Odland HH, Joten VM, Martinsen ØG, Tronstad C, Elvebakk O, Martinsen ØG (2019)
Measuring Blood Pulse Wave Velocity with Bioimpedance in Different Age Groups
Sensors (Basel), 19 (4)
DOI 10.3390/s19040850, PubMed 30791368

Babić A, Odland HH, Lyseggen E, Holm T, Ross S, Hopp E, Haugaa KH, Kongsgård E, Edvardsen T, Gérard O, Samset E (2019)
An image fusion tool for echo-guided left ventricular lead placement in cardiac resynchronization therapy: Performance and workflow integration analysis
Echocardiography, 36 (10), 1834-1845
DOI 10.1111/echo.14483, PubMed 31628770

Bisogno G, De Salvo GL, Bergeron C, Gallego Melcón S, Merks JH, Kelsey A, Martelli H, Minard-Colin V, Orbach D, Glosli H, Chisholm J, Casanova M, Zanetti I, Devalck C, Ben-Arush M, Mudry P, Ferman S, Jenney M, Ferrari A, European paediatric Soft tissue sarcoma Study Group (2019)
Vinorelbine and continuous low-dose cyclophosphamide as maintenance chemotherapy in patients with high-risk rhabdomyosarcoma (RMS 2005): a multicentre, open-label, randomised, phase 3 trial
Lancet Oncol, 20 (11), 1566-1575
DOI 10.1016/S1470-2045(19)30617-5, PubMed 31562043

Bogdanova M, Zabirnyk A, Malashicheva A, Enayati KZ, Karlsen TA, Kaljusto ML, Kvitting JE, Dissen E, Sullivan GJ, Kostareva A, Stensløkken KO, Rutkovskiy A, Vaage J (2019)
Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Sci Rep, 9 (1), 12934
DOI 10.1038/s41598-019-49016-0, PubMed 31506459

Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2019)
Sharing Progress in Neonatology (SPIN): A Critical Appraisal of Our Current Knowledge
Neonatology, 115 (4), 380-383
DOI 10.1159/000499359, PubMed 30974441

Diab SG, Godang K, Müller LO, Almaas R, de Lange C, Brunvand L, Hansen KM, Myhre AG, Døhlen G, Thaulow E, Bollerslev J, Möller T (2019)
Progressive loss of bone mass in children with Fontan circulation
Congenit Heart Dis
DOI 10.1111/chd.12848, PubMed 31600039

Dypvik J, Larsen S, Haavaldsen C, Saugstad OD, Eskild A (2019)
Placental Weight and Risk of Neonatal Death
JAMA Pediatr (in press)
DOI 10.1001/jamapediatrics.2019.4556, PubMed 31790552

Hesstvedt L, Gaustad P, Müller F, Torp Andersen C, Brunborg C, Mylvaganam H, Leiva RA, Berdal JE, Egil Ranheim T, Johnsen BO, Falch BM, Grimnes G, Skogen V, Haarr E, Sandmo Lyngøy A, Wik Larssen K, Hannula R, Åsheim Hansen B, Nordøy I, Norwegian Fungal Network (2019)
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
Infect Dis (Lond), 51 (6), 425-434
DOI 10.1080/23744235.2019.1595709, PubMed 31010380

Håheim LL, Nafstad P, Schwarze PE, Olsen I, Rønningen KS, Thelle DS (2019)
Oral health and cardiovascular disease risk factors and mortality of cerebral haemorrhage, cerebral infarction and unspecified stroke in elderly men: A prospective cohort study
Scand J Public Health, 1403494819879351 (in press)
DOI 10.1177/1403494819879351, PubMed 31814529

Jarvis KB, LeBlanc M, Tulstrup M, Nielsen RL, Albertsen BK, Gupta R, Huttunen P, Jónsson ÓG, Rank CU, Ranta S, Ruud E, Saks K, Trakymiene SS, Tuckuviene R, Schmiegelow K (2019)
Candidate single nucleotide polymorphisms and thromboembolism in acute lymphoblastic leukemia - A NOPHO ALL2008 study
Thromb Res, 184, 92-98
DOI 10.1016/j.thromres.2019.11.002, PubMed 31715544

Kahrs CR, Chuda K, Tapia G, Stene LC, Mårild K, Rasmussen T, Rønningen KS, Lundin KEA, Kramna L, Cinek O, Størdal K (2019)
Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort
BMJ, 364, l231
DOI 10.1136/bmj.l231, PubMed 30760441

Lin A, Sved Skottvoll F, Rayner S, Pedersen-Bjergaard S, Sullivan G, Krauss S, Ray Wilson S, Harrison S (2019)
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry
Electrophoresis
DOI 10.1002/elps.201900170, PubMed 31544246

Lund-Blix NA, Dong F, Mårild K, Seifert J, Barón AE, Waugh KC, Joner G, Størdal K, Tapia G, Stene LC, Johnson RK, Rewers MJ, Norris JM (2019)
Gluten Intake and Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in Children at Increased Risk of the Disease: The Diabetes Autoimmunity Study in the Young (DAISY)
Diabetes Care, 42 (5), 789-796
DOI 10.2337/dc18-2315, PubMed 30796108

Lund-Blix NA, Mårild K, Tapia G, Norris JM, Stene LC, Størdal K (2019)
Gluten Intake in Early Childhood and Risk of Celiac Disease in Childhood: A Nationwide Cohort Study
Am J Gastroenterol, 114 (8), 1299-1306
DOI 10.14309/ajg.0000000000000331, PubMed 31343439

Mårild K, Dong F, Lund-Blix NA, Seifert J, Barón AE, Waugh KC, Taki I, Størdal K, Tapia G, Stene LC, Johnson RK, Liu E, Rewers MJ, Norris JM (2019)
Gluten Intake and Risk of Celiac Disease: Long-Term Follow-up of an At-Risk Birth Cohort
Am J Gastroenterol, 114 (8), 1307-1314
DOI 10.14309/ajg.0000000000000255, PubMed 31082869

Perez M, Robbins ME, Revhaug C, Saugstad OD (2019)
Oxygen radical disease in the newborn, revisited: Oxidative stress and disease in the newborn period
Free Radic Biol Med, 142, 61-72
DOI 10.1016/j.freeradbiomed.2019.03.035, PubMed 30954546

Revhaug C, Bik-Multanowski M, Zasada M, Rognlien AGW, Günther CC, Ksiązek T, Madetko-Talowska A, Szewczyk K, Grabowska A, Kwinta P, Pietrzyk JJ, Baumbusch LO, Saugstad OD (2019)
Immune System Regulation Affected by a Murine Experimental Model of Bronchopulmonary Dysplasia: Genomic and Epigenetic Findings
Neonatology, 116 (3), 269-277
DOI 10.1159/000501461, PubMed 31454811

Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jørgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM (2019)
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Diabetes, 68 (5), 988-1001
DOI 10.2337/db18-0686, PubMed 30833470

Stensvold E, Myklebust TÅ, Cappelen J, Due-Tønnessen BJ, Due-Tønnessen P, Kepka A, Johannesen TB, Krossnes B, Lundar T, Maric S, Miletic H, Moholdt V, Myrmel KS, Nordberg T, Rydland J, Stokland T, Solem K, Solheim O, Torsvik I, Wikran GC, Zeller B, Wesenberg F, Bechensteen AG, Brandal P (2019)
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Pediatr Blood Cancer, 66 (10), e27910
DOI 10.1002/pbc.27910, PubMed 31264356

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Te Pas A, Plavka R, Roehr CC, Saugstad OD, Simeoni U, Speer CP, Vento M, Visser GHA, Halliday HL (2019)
European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update
Neonatology, 115 (4), 432-450
DOI 10.1159/000499361, PubMed 30974433

Tapia G, Mårild K, Dahl SR, Lund-Blix NA, Viken MK, Lie BA, Njølstad PR, Joner G, Skrivarhaug T, Cohen AS, Størdal K, Stene LC (2019)
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241

Thastrup M, Marquart HV, Levinsen M, Grell K, Abrahamsson J, Albertsen BK, Frandsen TL, Harila-Saari A, Lähteenmäki PM, Niinimäki R, Pronk CJ, Ulvmoen A, Vaitkevičienė G, Taskinen M, Schmiegelow K, Nordic Society of Pediatric Hematology and Oncology (NOPHO) (2019)
Flow cytometric detection of leukemic blasts in cerebrospinal fluid predicts risk of relapse in childhood acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology study
Leukemia (in press)
DOI 10.1038/s41375-019-0570-1, PubMed 31534171

Thaulow CM, Blix HS, Eriksen BH, Ask I, Myklebust TÅ, Berild D (2019)
Using a period incidence survey to compare antibiotic use in children between a university hospital and a district hospital in a country with low antimicrobial resistance: a prospective observational study
BMJ Open, 9 (5), e027836
DOI 10.1136/bmjopen-2018-027836, PubMed 31138583

Vento M, Saugstad OD (2019)
Targeting Oxygen in Term and Preterm Infants Starting at Birth
Clin Perinatol, 46 (3), 459-473
DOI 10.1016/j.clp.2019.05.013, PubMed 31345541

Warris A, Pana ZD, Oletto A, Lundin R, Castagnola E, Lehrnbecher T, Groll AH, Roilides E, Andersen CT, Arendrup MC, Arsenijevic VA, Bianchini S, von Both U, Chmelnik M, Controzzi T, Emonts M, Esposito S, Ferreras-Antolin L, Henriet S, Iosifidis E, Irwin A, Kopsidas J, Lagrou K, Lyall H, Casteleiro AM et al. (2019)
Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study
Pediatr Infect Dis J (in press)
DOI 10.1097/INF.0000000000002530, PubMed 31725552

Xu Z, Lie RT, Wilcox AJ, Saugstad OD, Taylor JA (2019)
A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts
Clin Epigenetics, 11 (1), 40
DOI 10.1186/s13148-019-0638-9, PubMed 30832715

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

Zasada M, Madetko-Talowska A, Revhaug C, Rognlien AGW, Baumbusch LO, Książek T, Szewczyk K, Grabowska A, Bik-Multanowski M, Józef Pietrzyk J, Kwinta P, Didrik Saugstad O (2019)
Short- and long-term impact of hyperoxia on the blood and retinal cells' transcriptome in a mouse model of oxygen-induced retinopathy
Pediatr Res (in press)
DOI 10.1038/s41390-019-0598-y, PubMed 31578039

Zasada M, Suski M, Bokiniec R, Szwarc-Duma M, Borszewska-Kornacka MK, Madej J, Bujak-Giżycka B, Madetko-Talowska A, Revhaug C, Baumbusch LO, Saugstad OD, Pietrzyk JJ, Kwinta P (2019)
Comparative two time-point proteome analysis of the plasma from preterm infants with and without bronchopulmonary dysplasia
Ital J Pediatr, 45 (1), 112
DOI 10.1186/s13052-019-0676-0, PubMed 31445514

Aalen JM, Remme EW, Larsen CK, Andersen OS, Krogh M, Duchenne J, Hopp E, Ross S, Beela AS, Kongsgaard E, Bergsland J, Odland HH, Skulstad H, Opdahl A, Voigt JU, Smiseth OA (2019)
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging, 12 (12), 2402-2413
DOI 10.1016/j.jcmg.2018.11.030, PubMed 30772230

 
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