Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2016 from OUS - Department of Paediatric Medicine
61 publications found
Psychiatric comorbidity in children and youth with epilepsy: An association with executive dysfunction?
Epilepsy Behav, 56, 88-94
DOI 10.1016/j.yebeh.2016.01.007, PubMed 26851646
Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
Scand J Immunol, 83 (3), 188-94
DOI 10.1111/sji.12406, PubMed 26708691
Epidemiology and Health-Related Quality of Life in Hypoparathyroidism in Norway
J Clin Endocrinol Metab, 101 (8), 3045-53
DOI 10.1210/jc.2016-1477, PubMed 27186861
Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007
Cancer Med, 5 (8), 1765-75
DOI 10.1002/cam4.741, PubMed 27228363
Vitamin D levels and atopic eczema in infancy and early childhood in Norway: a cohort study
Br J Dermatol, 175 (1), 95-101
DOI 10.1111/bjd.14537, PubMed 26972308
Lung Function Monitoring; A Randomized Agreement Study
Open Respir Med J, 10, 51-7
DOI 10.2174/1874306401610010051, PubMed 27583055
Angiotensin II type 1 receptor antibodies in childhood kidney transplantation
Pediatr Transplant, 20 (5), 627-32
DOI 10.1111/petr.12728, PubMed 27251358
Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015
Allergy, 71 (11), 1513-1525
DOI 10.1111/all.12880, PubMed 26970340
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)
Clin Transl Allergy, 6, 29
DOI 10.1186/s13601-016-0116-9, PubMed 27478588
ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle
Clin Transl Allergy, 6, 47
DOI 10.1186/s13601-016-0137-4, PubMed 28050247
MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis
J Allergy Clin Immunol, 138 (2), 367-374.e2
DOI 10.1016/j.jaci.2016.03.025, PubMed 27260321
Identification of a novel BCKDHA deletion causing maple syrup urine disease
Meta Gene, 10, 86-89
Early reduced myocardial diastolic function in children and adolescents with type 1 diabetes mellitus a population-based study
BMC Cardiovasc Disord, 16, 103
DOI 10.1186/s12872-016-0288-1, PubMed 27225446
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1
J Clin Endocrinol Metab, 101 (8), 2975-83
DOI 10.1210/jc.2016-1821, PubMed 27253668
Burden of Rotavirus Disease in Norway: Using National Registries for Public Health Research
Pediatr Infect Dis J, 35 (4), 396-400
DOI 10.1097/INF.0000000000001055, PubMed 26974747
Glycemic control and complications in patients with type 1 diabetes - a registry-based longitudinal study of adolescents and young adults
Pediatr Diabetes, 18 (3), 188-195
DOI 10.1111/pedi.12372, PubMed 26875589
Utility of Global Longitudinal Strain by Echocardiography to Detect Left Ventricular Dysfunction in Long-Term Adult Survivors of Childhood Lymphoma and Acute Lymphoblastic Leukemia
Am J Cardiol, 118 (3), 446-52
DOI 10.1016/j.amjcard.2016.05.021, PubMed 27296561
Right ventricular function in long-term adult survivors of childhood lymphoma and acute lymphoblastic leukaemia
Eur Heart J Cardiovasc Imaging, 17 (7), 735-41
DOI 10.1093/ehjci/jew018, PubMed 26917232
Defective hepatic bicarbonate production due to carbonic anhydrase VA deficiency leads to early-onset life-threatening metabolic crisis
Genet Med, 18 (10), 991-1000
DOI 10.1038/gim.2015.201, PubMed 26913920
Access to clinical trials for adolescents with soft tissue sarcomas: Enrollment in European pediatric Soft tissue sarcoma Study Group (EpSSG) protocols
Pediatr Blood Cancer, 64 (6)
DOI 10.1002/pbc.26348, PubMed 27882658
The Jervell and Lange-Nielsen syndrome; atrial pacing combined with ß-blocker therapy, a favorable approach in young high-risk patients with long QT syndrome?
Heart Rhythm, 13 (11), 2186-2192
DOI 10.1016/j.hrthm.2016.07.020, PubMed 27451284
Causes of death in childhood-onset Type 1 diabetes: long-term follow-up
Diabet Med, 34 (1), 56-63
DOI 10.1111/dme.13114, PubMed 26996105
Long-term Mortality and End-Stage Renal Disease in a Type 1 Diabetes Population Diagnosed at Age 15-29 Years in Norway
Diabetes Care, 40 (1), 38-45
DOI 10.2337/dc16-1213, PubMed 27797927
A novel Direct MIC-gradient Strip Method to screen for antibiotic-resistant faecal Enterobacteriaceae
J Microbiol Methods, 129, 94-97
DOI 10.1016/j.mimet.2016.08.007, PubMed 27526992
Intra-individual changes in DNA methylation not mediated by cell-type composition are correlated with aging during childhood
Clin Epigenetics, 8, 110
DOI 10.1186/s13148-016-0277-3, PubMed 27785156
Reproduction and marriage among male survivors of cancer in childhood, adolescence and young adulthood: a national cohort study
Br J Cancer, 114 (3), 348-56
DOI 10.1038/bjc.2015.455, PubMed 26794280
Suicide and violent deaths in survivors of cancer in childhood, adolescence and young adulthood-A national cohort study
Int J Cancer, 140 (3), 575-580
DOI 10.1002/ijc.30474, PubMed 27750385
Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study
Cancer, 122 (24), 3873-3882
DOI 10.1002/cncr.30253, PubMed 27518040
Sexual problems in people with refractory epilepsy
Epilepsy Behav, 61, 174-179
DOI 10.1016/j.yebeh.2016.05.038, PubMed 27371882
Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
BMJ Open Diabetes Res Care, 4 (1), e000219
DOI 10.1136/bmjdrc-2016-000219, PubMed 27933184
Timing of renal replacement therapy does not influence survival and growth in children with congenital nephrotic syndrome caused by mutations in NPHS1: data from the ESPN/ERA-EDTA Registry
Pediatr Nephrol, 31 (12), 2317-2325
DOI 10.1007/s00467-016-3517-z, PubMed 27761660
The second report of the Nordic Pediatric Renal Transplantation Registry 1997-2012: More infant recipients and improved graft survivals
Pediatr Transplant, 20 (3), 364-71
DOI 10.1111/petr.12686, PubMed 26857893
Glomerulopathy in patients with distal duplication of chromosome 6p
BMC Nephrol, 17, 32
DOI 10.1186/s12882-016-0246-2, PubMed 27000031
Multidrug-resistant tuberculosis in Norway: a nationwide study, 1995-2014
Int J Tuberc Lung Dis, 20 (6), 786-92
DOI 10.5588/ijtld.15.0895, PubMed 27155182
Clinical features, therapeutic interventions and long-term aspects of hemolytic-uremic syndrome in Norwegian children: a nationwide retrospective study from 1999-2008
BMC Infect Dis, 16, 285
DOI 10.1186/s12879-016-1627-7, PubMed 27297224
Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome
Brain Pathol, 27 (4), 411-418
DOI 10.1111/bpa.12413, PubMed 27380723
Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry
Diabetologia, 60 (4), 625-635
DOI 10.1007/s00125-016-4167-1, PubMed 27913849
Mortality and complications in 3495 children with isolated ventricular septal defects
Arch Dis Child, 101 (9), 808-13
DOI 10.1136/archdischild-2015-310154, PubMed 27091847
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Am J Hum Genet, 98 (4), 680-96
DOI 10.1016/j.ajhg.2016.02.019, PubMed 27040690
Tailoring the delivery of cancer diagnosis to adolescent and young adult patients displaying strong emotions: An observational study of two cases
Int J Qual Stud Health Well-being, 11, 30763
DOI 10.3402/qhw.v11.30763, PubMed 27125477
A content analysis of emotional concerns expressed at the time of receiving a cancer diagnosis: An observational study of consultations with adolescent and young adult patients and their family members
Eur J Oncol Nurs, 26, 1-8
DOI 10.1016/j.ejon.2016.10.005, PubMed 28069147
Patient-provider communication about the emotional cues and concerns of adolescent and young adult patients and their family members when receiving a diagnosis of cancer
Patient Educ Couns, 99 (10), 1576-83
DOI 10.1016/j.pec.2016.03.028, PubMed 27139576
Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study
Genes Chromosomes Cancer, 55 (9), 719-26
DOI 10.1002/gcc.22373, PubMed 27153159
Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes
Diabetes, 65 (5), 1362-9
DOI 10.2337/db15-1615, PubMed 26858360
Maternal Diabetes, Birth Weight, and Neonatal Risk of Congenital Heart Defects in Norway, 1994-2009
Obstet Gynecol, 128 (5), 1116-1125
DOI 10.1097/AOG.0000000000001694, PubMed 27741197
Effect of age and body weight on toxicity and survival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004
Haematologica, 101 (11), 1359-1367
DOI 10.3324/haematol.2016.146175, PubMed 27470605
Early sexual debut in Norwegian youth with epilepsy: A population-based study
Epilepsy Behav, 56, 1-4
DOI 10.1016/j.yebeh.2015.12.014, PubMed 26789985
Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes
Diabetes, 65 (10), 3104-10
DOI 10.2337/db16-0616, PubMed 27422384
Impaired intention-to-treat survival after listing for liver transplantation in children with biliary atresia compared to other chronic liver diseases: 20 years' experience from the Nordic countries
Pediatr Transplant, 21 (2)
DOI 10.1111/petr.12851, PubMed 27957786
Serological markers in diagnosis of pediatric inflammatory bowel disease and as predictors for early tumor necrosis factor blocker therapy
Scand J Gastroenterol, 52 (4), 414-419
DOI 10.1080/00365521.2016.1259653, PubMed 27887202
Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia-association with young age and myeloid sarcomas?
Exp Hematol Oncol, 5, 8
DOI 10.1186/s40164-016-0037-2, PubMed 26949571
RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Oncol Rep, 36 (5), 2481-2488
DOI 10.3892/or.2016.5119, PubMed 27667292
Bioimpedance measurements of temporal changes in beating hearts
Biomed. Phys. Eng. Express, 2 (6), 065015
The severity of acute bronchiolitis in infants was associated with quality of life nine months later
Acta Paediatr, 105 (7), 834-41
DOI 10.1111/apa.13396, PubMed 26970427
Maintenance therapy of childhood acute lymphoblastic leukemia revisited-Should drug doses be adjusted by white blood cell, neutrophil, or lymphocyte counts?
Pediatr Blood Cancer, 63 (12), 2104-2111
DOI 10.1002/pbc.26139, PubMed 27447547
Vitamin D-binding protein and 25-hydroxyvitamin D during pregnancy in mothers whose children later developed type 1 diabetes
Diabetes Metab Res Rev, 32 (8), 883-890
DOI 10.1002/dmrr.2812, PubMed 27103201
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283
Prospective study of thromboembolism in 1038 children with acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology (NOPHO) study
J Thromb Haemost, 14 (3), 485-94
DOI 10.1111/jth.13236, PubMed 26707629
Infants Requiring Maintenance Dialysis: Outcomes of Hemodialysis and Peritoneal Dialysis
Am J Kidney Dis, 69 (5), 617-625
DOI 10.1053/j.ajkd.2016.09.024, PubMed 27955924
Perceived exercise limitation in asthma: The role of disease severity, overweight, and physical activity in children
Pediatr Allergy Immunol, 28 (1), 86-92
DOI 10.1111/pai.12670, PubMed 27734537
Psychological barriers to optimal insulin therapy: more concerns in adolescent females than males
BMJ Open Diabetes Res Care, 4 (1), e000203
DOI 10.1136/bmjdrc-2016-000203, PubMed 27403325