Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2017 from OUS - Department of Ophthalmology

37 publications found

Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL (2017)
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
DOI 10.1186/s13075-017-1228-x, PubMed 28122643

Arjamaa O, Aaltonen V, Piippo N, Csont T, Petrovski G, Kaarniranta K, Kauppinen A (2017)
Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells
Graefes Arch Clin Exp Ophthalmol, 255 (9), 1757-1762
DOI 10.1007/s00417-017-3711-0, PubMed 28631245

Berg K, Roald AB, Navaratnam J, Bragadóttir R (2017)
An 8-year follow-up of anti-vascular endothelial growth factor treatment with a treat-and-extend modality for neovascular age-related macular degeneration
Acta Ophthalmol, 95 (8), 796-802
DOI 10.1111/aos.13522, PubMed 28926190

Chen X, Utheim ØA, Xiao J, Adil MY, Stojanovic A, Tashbayev B, Jensen JL, Utheim TP (2017)
Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
PLoS One, 12 (9), e0184284
DOI 10.1371/journal.pone.0184284, PubMed 28886085

Colijn JM, Buitendijk GHS, Prokofyeva E, Alves D, Cachulo ML, Khawaja AP, Cougnard-Gregoire A, Merle BMJ, Korb C, Erke MG, Bron A, Anastasopoulos E, Meester-Smoor MA, Segato T, Piermarocchi S, de Jong PTVM, Vingerling JR, Topouzis F, Creuzot-Garcher C, Bertelsen G, Pfeiffer N, Fletcher AE, Foster PJ, Silva R, Korobelnik JF et al. (2017)
Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future
Ophthalmology, 124 (12), 1753-1763
DOI 10.1016/j.ophtha.2017.05.035, PubMed 28712657

de Rodez Benavent SA, Nygaard GO, Harbo HF, Tønnesen S, Sowa P, Landrø NI, Wendel-Haga M, Etholm L, Nilsen KB, Drolsum L, Kerty E, Celius EG, Laeng B (2017)
Fatigue and cognition: Pupillary responses to problem-solving in early multiple sclerosis patients
Brain Behav, 7 (7), e00717
DOI 10.1002/brb3.717, PubMed 28729927

Drobnjak D, Munch IC, Glümer C, Færch K, Kessel L, Larsen M, Veiby NCBB (2017)
Relationship between retinal vessel diameters and retinopathy in the Inter99 Eye Study
J Clin Transl Endocrinol, 8, 22-28
DOI 10.1016/j.jcte.2017.03.002, PubMed 29067255

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res (in press)
DOI 10.1007/s12253-017-0355-7, PubMed 29098521

Fostad IG, Eidet JR, Lagali NS, Dartt DA, Ræder S, Messelt EB, Utheim TP (2017)
Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
Microsc Microanal, 23 (1), 88-96
DOI 10.1017/S1431927617000022, PubMed 28162126

Glatz W, Steinwender G, Tarmann L, Malle EM, Schörkhuber M, Wackernagel W, Petrovski G, Wedrich A, Ivastinovic D (2017)
Vitreous hyper-reflective dots in pseudophakic cystoid macular edema assessed with optical coherence tomography
PLoS One, 12 (12), e0189194
DOI 10.1371/journal.pone.0189194, PubMed 29244855

Hagem AM, Thorsrud A, Sandvik GF, Råen M, Drolsum L (2017)
Collagen crosslinking with conventional and accelerated ultraviolet-A irradiation using riboflavin with hydroxypropyl methylcellulose
J Cataract Refract Surg, 43 (4), 511-517
DOI 10.1016/j.jcrs.2017.01.013, PubMed 28532937

Holte KB, Juel NG, Brox JI, Hanssen KF, Fosmark DS, Sell DR, Monnier VM, Berg TJ (2017)
Hand, shoulder and back stiffness in long-term type 1 diabetes; cross-sectional association with skin collagen advanced glycation end-products. The Dialong study
J Diabetes Complications, 31 (9), 1408-1414
DOI 10.1016/j.jdiacomp.2017.06.007, PubMed 28705609

Hongisto H, Jylhä A, Nättinen J, Rieck J, Ilmarinen T, Veréb Z, Aapola U, Beuerman R, Petrovski G, Uusitalo H, Skottman H (2017)
Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium
Sci Rep, 7 (1), 6016
DOI 10.1038/s41598-017-06233-9, PubMed 28729539

Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A (2017)
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells
Sci Rep, 7 (1), 16169
DOI 10.1038/s41598-017-16524-w, PubMed 29170454

Hytti M, Szabó D, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Petrovski G, Kauppinen A (2017)
Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells
J Nutr Biochem, 42, 37-42
DOI 10.1016/j.jnutbio.2016.12.014, PubMed 28113103

Islam R, Eidet JR, Badian RA, Lippestad M, Messelt E, Griffith M, Dartt DA, Utheim TP (2017)
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
Sci Rep, 7 (1), 674
DOI 10.1038/s41598-017-00417-z, PubMed 28386069

Jackson CJ, Reppe S, Eidet JR, Eide L, Tønseth KA, Bergersen LH, Dartt DA, Griffith M, Utheim TP (2017)
Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
Sci Rep, 7 (1), 8206
DOI 10.1038/s41598-017-08586-7, PubMed 28811665

Jackson CJ, Tønseth KA, Utheim TP (2017)
Cultured epidermal stem cells in regenerative medicine
Stem Cell Res Ther, 8 (1), 155
DOI 10.1186/s13287-017-0587-1, PubMed 28676094

Johannsdottir IMR, Hamre H, Fosså SD, Loge JH, Drolsum L, Lund MB, Nordsletten L, Kiserud C (2017)
Adverse Health Outcomes and Associations with Self-Reported General Health in Childhood Lymphoma Survivors
J Adolesc Young Adult Oncol, 6 (3), 470-476
DOI 10.1089/jayao.2017.0018, PubMed 28837384

Johnsen EO, Frøen RC, Olstad OK, Nicolaissen B, Petrovski G, Moe MC, Noer A (2017)
Proliferative Cells Isolated from the Adult Human Peripheral Retina only Transiently Upregulate Key Retinal Markers upon Induced Differentiation
Curr Eye Res, 43 (3), 340-349
DOI 10.1080/02713683.2017.1403630, PubMed 29161152

Josifovska N, Szabó DJ, Nagymihály R, Veréb Z, Facskó A, Eriksen K, Moe MC, Petrovski G (2017)
Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy
Cont Lens Anterior Eye, 40 (5), 283-292
DOI 10.1016/j.clae.2017.04.002, PubMed 28550976

Jørstad ØK, Faber RT, Moe MC (2017)
Two-year functional and anatomical results after converting treatment resistant eyes with exudative age-related macular degeneration to aflibercept in accordance with a treat and extend protocol
Acta Ophthalmol, 95 (5), 460-463
DOI 10.1111/aos.13480, PubMed 28556485

Kristianslund O, Råen M, Østern AE, Drolsum L (2017)
Glaucoma and Intraocular Pressure in Patients Operated for Late In-the-bag Intraocular Lens Dislocation: A Randomized Clinical Trial
Am J Ophthalmol, 176, 219-227
DOI 10.1016/j.ajo.2017.01.026, PubMed 28167054

Kristianslund O, Østern AE, Drolsum L (2017)
Astigmatism and Refractive Outcome After Late In-The-Bag Intraocular Lens Dislocation Surgery: A Randomized Clinical Trial
Invest Ophthalmol Vis Sci, 58 (11), 4747-4753
DOI 10.1167/iovs.17-22723, PubMed 28973318

Landsend ES, Utheim ØA, Pedersen HR, Lagali N, Baraas RC, Utheim TP (2017)
The genetics of congenital aniridia-a guide for the ophthalmologist
Surv Ophthalmol, 63 (1), 105-113
DOI 10.1016/j.survophthal.2017.09.004, PubMed 28923585

Lindvik H, Lødrup Carlsen KC, Mowinckel P, Navaratnam J, Borres MP, Carlsen KH (2017)
Conjunctival provocation test in diagnosis of peanut allergy in children
Clin Exp Allergy, 47 (6), 785-794
DOI 10.1111/cea.12899, PubMed 28160326

Lytvynchuk L, Sergienko A, Savytska I, Albert R, Glittenberg C, Binder S, Petrovski G (2017)
Comparative cyto-histological study of needle tip aspirates and entry sites after intravitreal injection using different needle types
PLoS One, 12 (7), e0174467
DOI 10.1371/journal.pone.0174467, PubMed 28692684

Magnusdottir V, Vehmeijer WB, Eliasdottir TS, Hardarson SH, Schalij-Delfos NE, Stefánsson E (2017)
Fundus imaging in newborn children with wide-field scanning laser ophthalmoscope
Acta Ophthalmol, 95 (8), 842-844
DOI 10.1111/aos.13453, PubMed 28391630

Márkus B, Pató Z, Sarang Z, Albert R, Tőzsér J, Petrovski G, Csősz É (2017)
The proteomic profile of a mouse model of proliferative vitreoretinopathy
FEBS Open Bio, 7 (8), 1166-1177
DOI 10.1002/2211-5463.12252, PubMed 28781956

Nagymihály R, Veréb Z, Albert R, Sidney L, Dua H, Hopkinson A, Petrovski G (2017)
Cultivation and characterisation of the surface markers and carbohydrate profile of human corneal endothelial cells
Clin Exp Ophthalmol, 45 (5), 509-519
DOI 10.1111/ceo.12903, PubMed 28032398

Nagymihály R, Veréb Z, Facskó A, Moe MC, Petrovski G (2017)
Effect of Isolation Technique and Location on the Phenotype of Human Corneal Stroma-Derived Cells
Stem Cells Int, 2017, 9275248
DOI 10.1155/2017/9275248, PubMed 29213290

Ness C, Garred Ø, Eide NA, Kumar T, Olstad OK, Bærland TP, Petrovski G, Moe MC, Noer A (2017)
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs
Mol Vis, 23, 680-694
PubMed 29033534

Schmidt-Erfurth U, Garcia-Arumi J, Bandello F, Berg K, Chakravarthy U, Gerendas BS, Jonas J, Larsen M, Tadayoni R, Loewenstein A (2017)
Guidelines for the Management of Diabetic Macular Edema by the European Society of Retina Specialists (EURETINA)
Ophthalmologica, 237 (4), 185-222
DOI 10.1159/000458539, PubMed 28423385

Szabó DJ, Nagymihály R, Veréb Z, Josifovska N, Noer A, Liskova P, Facskó A, Moe MC, Petrovski G (2017)
Ex vivo 3D human corneal stroma model for Schnyder corneal dystrophy - role of autophagy in its pathogenesis and resolution
Histol Histopathol, 33 (5), 455-462
DOI 10.14670/HH-11-928, PubMed 28872183

Tazmini K, Meling TR, Skattør TH, Jørstad ØK, Jørgensen AP (2017)
A woman in her 50s with chronic fatigue syndrome, sepsis and hyponatraemia
Tidsskr Nor Laegeforen, 137 (5), 372-377
DOI 10.4045/tidsskr.16.0896, PubMed 28272569

Thorsrud A, Sandvik GF, Hagem AM, Drolsum L (2017)
Measuring the depth of crosslinking demarcation line in vivo: Comparison of methods and devices
J Cataract Refract Surg, 43 (2), 255-262
DOI 10.1016/j.jcrs.2017.01.003, PubMed 28366375

Aass C, Norheim I, Eriksen EF, Børnick EC, Thorsby PM, Pepaj M (2017)
Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy
PLoS One, 12 (4), e0175274
DOI 10.1371/journal.pone.0175274, PubMed 28419103

 
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