Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2016 from OUS - Department of Neurology
85 publications found
Psychiatric comorbidity in children and youth with epilepsy: An association with executive dysfunction?
Epilepsy Behav, 56, 88-94
DOI 10.1016/j.yebeh.2016.01.007, PubMed 26851646
The Mortality Associated With Chronic Widespread Musculoskeletal Complaints: A Systematic Review of the Literature
Musculoskeletal Care, 15 (2), 104-113
DOI 10.1002/msc.1156, PubMed 27430167
Chronic musculoskeletal complaints as a predictor of mortality-The HUNT study
Pain, 157 (7), 1443-1447
DOI 10.1097/j.pain.0000000000000537, PubMed 26919487
The role of antiepileptic drugs in sudden unexpected death in epilepsy
Seizure, 43, 56-60
DOI 10.1016/j.seizure.2016.11.005, PubMed 27886630
[Sudden unexpected death in epilepsy (SUDEP)]
Tidsskr Nor Laegeforen, 136 (2), 131-5
DOI 10.4045/tidsskr.14.0640, PubMed 26813818
Ictal EEG source imaging in presurgical evaluation: High agreement between analysis methods
Seizure, 43, 1-5
DOI 10.1016/j.seizure.2016.09.017, PubMed 27764709
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Genes Immun, 17 (2), 118-27
DOI 10.1038/gene.2015.61, PubMed 26765264
Level of education and multiple sclerosis risk over a 50-year period: Registry-based sibling study
Mult Scler, 23 (2), 213-219
DOI 10.1177/1352458516646863, PubMed 27207453
Increased risk for clinical onset of myasthenia gravis during the postpartum period
Neurology, 87 (20), 2139-2145
DOI 10.1212/WNL.0000000000003339, PubMed 27770065
From genetic associations to functional studies in multiple sclerosis
Eur J Neurol, 23 (5), 847-53
DOI 10.1111/ene.12981, PubMed 26948534
Degree and Timing of Intensive Blood Pressure Lowering on Hematoma Growth in Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial-2 Results
Stroke, 47 (6), 1651-3
DOI 10.1161/STROKEAHA.116.013326, PubMed 27143274
Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels
Acta Psychiatr Scand, 134 (1), 40-7
DOI 10.1111/acps.12576, PubMed 27028967
Getting to the Heart of Emotion Regulation in Youth: The Role of Interoceptive Sensitivity, Heart Rate Variability, and Parental Psychopathology
PLoS One, 11 (10), e0164615
DOI 10.1371/journal.pone.0164615, PubMed 27741261
A New Approach for Epilepsy
Cerebrum, 2016
PubMed 27408679
Prevalence of Two-Syllable Digits Affecting Forward Digit Span Test Score: A Potential Reliability Factor in Digit Span Tests and New Light to the Word Length Effect
SAGE Open, 6 (4), 2158244016681825
Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas
Hum Genet, 135 (4), 425-439
DOI 10.1007/s00439-016-1638-x, PubMed 26899160
Dentate gyrus-cornu ammonis (CA) 4 volume is decreased and associated with depressive episodes and lipid peroxidation in bipolar II disorder: Longitudinal and cross-sectional analyses
Bipolar Disord, 18 (8), 657-668
DOI 10.1111/bdi.12457, PubMed 27995733
Carotid Atherosclerosis in Adult Patients with Persistently Active Juvenile Idiopathic Arthritis Compared with Healthy Controls
J Rheumatol, 43 (4), 810-5
DOI 10.3899/jrheum.150499, PubMed 26879363
[Idiopathic intracranial hypertension as a cause of headache]
Tidsskr Nor Laegeforen, 136 (22), 1895-1898
DOI 10.4045/tidsskr.16.0222, PubMed 27929555
Health Care Delivery Practices in Huntington's Disease Specialty Clinics: An International Survey
J Huntingtons Dis, 5 (2), 207-13
DOI 10.3233/JHD-160192, PubMed 27372053
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies
Neurol.-Genet., 2 (4), eB7
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Nat Genet, 48 (8), 856-66
DOI 10.1038/ng.3598, PubMed 27322543
Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study
Mult Scler J Exp Transl Clin, 2, 2055217316682976
DOI 10.1177/2055217316682976, PubMed 28607748
Sleep problems in children and adolescents with epilepsy: Associations with psychiatric comorbidity
Epilepsy Behav, 62, 14-9
DOI 10.1016/j.yebeh.2016.06.015, PubMed 27448238
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls
Neuropsychiatr Dis Treat, 12, 2419-2423
DOI 10.2147/NDT.S113586, PubMed 27703359
Is there a U-shaped relationship between physical activity in leisure time and risk of chronic low back pain? A follow-up in the HUNT Study
BMC Public Health, 16, 306
DOI 10.1186/s12889-016-2970-8, PubMed 27068452
[What causes febrile convulsions?]
Tidsskr Nor Laegeforen, 136 (1), 36-8
DOI 10.4045/tidsskr.14.1503, PubMed 26757658
Subcortical volumetric abnormalities in bipolar disorder
Mol Psychiatry, 21 (12), 1710-1716
DOI 10.1038/mp.2015.227, PubMed 26857596
Severe inflammatory disease activity 14 months after cessation of Natalizumab in a patient with Leber's optic neuropathy and multiple sclerosis - a case report
BMC Neurol, 16 (1), 197
DOI 10.1186/s12883-016-0720-2, PubMed 27756254
A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep
Psychoneuroendocrinology, 77, 1-8
DOI 10.1016/j.psyneuen.2016.11.029, PubMed 27987429
Spatial memory is impaired by peripubertal GnRH agonist treatment and testosterone replacement in sheep
Psychoneuroendocrinology, 75, 173-182
DOI 10.1016/j.psyneuen.2016.10.016, PubMed 27837697
CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults
Neurobiol Aging, 49, 138-144
DOI 10.1016/j.neurobiolaging.2016.09.012, PubMed 27794264
A polymorphic Alu insertion that mediates distinct disease-associated deletions
Eur J Hum Genet, 24 (9), 1371-4
DOI 10.1038/ejhg.2016.20, PubMed 26932189
New anticoagulants in combination with antiplatelet agents
Tidsskr Nor Laegeforen, 136 (18), 1543-1546
DOI 10.4045/tidsskr.15.1356, PubMed 27731598
Blood Pressure Management in Acute Stroke
Curr Hypertens Rev, 12 (2), 121-6
DOI 10.2174/1573402112666160302102711, PubMed 26931471
Early blood pressure lowering treatment in acute stroke. Ordinal analysis of vascular events in the Scandinavian Candesartan Acute Stroke Trial (SCAST)
J Hypertens, 34 (8), 1594-8
DOI 10.1097/HJH.0000000000000980, PubMed 27228435
Blood Pressure Lowering Treatment in Patients with Carotid Artery Stenosis
Curr Hypertens Rev, 12 (2), 148-55
DOI 10.2174/157340211202160525010133, PubMed 27292176
Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood
BMC Genet, 17, 59
DOI 10.1186/s12863-016-0367-4, PubMed 27080863
Power estimation for non-standardized multisite studies
Neuroimage, 134, 281-294
DOI 10.1016/j.neuroimage.2016.03.051, PubMed 27039700
SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing
PLoS One, 11 (9), e0161789
DOI 10.1371/journal.pone.0161789, PubMed 27598514
Pathological nociceptors in two patients with erythromelalgia-like symptoms and rare genetic Nav 1.9 variants
Brain Behav, 6 (10), e00528
DOI 10.1002/brb3.528, PubMed 27781142
Valproic Acid as a Promising Co-Treatment With Paclitaxel and Doxorubicin in Different Ovarian Carcinoma Cell Lines
Int J Gynecol Cancer, 26 (9), 1546-1556
DOI 10.1097/IGC.0000000000000814, PubMed 27654264
High-throughput sequencing of immune repertoires in multiple sclerosis
Ann Clin Transl Neurol, 3 (4), 295-306
DOI 10.1002/acn3.295, PubMed 27081660
Early sexual debut in Norwegian youth with epilepsy: A population-based study
Epilepsy Behav, 56, 1-4
DOI 10.1016/j.yebeh.2015.12.014, PubMed 26789985
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis
Atherosclerosis, 257, 216-223
DOI 10.1016/j.atherosclerosis.2016.11.026, PubMed 27940038
A Role for the Transcription Factor Nk2 Homeobox 1 in Schizophrenia: Convergent Evidence from Animal and Human Studies
Front Behav Neurosci, 10, 59
DOI 10.3389/fnbeh.2016.00059, PubMed 27064909
[MRI in multiple sclerosis]
Tidsskr Nor Laegeforen, 136 (16), 1373-6
DOI 10.4045/tidsskr.15.1361, PubMed 27637059
Non-paraneoplastic limbic encephalitis and central nervous HHV-6B reactivation: Causality or coincidence?
Neuropathology, 36 (4), 376-80
DOI 10.1111/neup.12283, PubMed 27431532
Implicit Gender Stereotypes and Essentialist Beliefs Predict Preservice Teachers' Tracking Recommendations
J. Exp. Educ., 84 (1), 152-174
Symptoms and signs possibly indicating segmental, discogenic pain. A fusion study with 18 years of follow-up
Scand J Pain, 16, 213-220
DOI 10.1016/j.sjpain.2016.10.007, PubMed 28850405
Standardized Assessment of Hereditary Ataxia Patients in Clinical Studies
Mov Disord Clin Pract, 3 (3), 230-240
DOI 10.1002/mdc3.12315, PubMed 30363623
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962
Clinical and molecular characteristics in three families with biallelic mutations in IGHMBP2
Neuromuscul Disord, 26 (9), 570-5
DOI 10.1016/j.nmd.2016.06.457, PubMed 27450922
Fully automated structural MRI of the brain in clinical dementia workup
Acta Radiol, 58 (6), 740-747
DOI 10.1177/0284185116669874, PubMed 27687251
A cumulative genetic risk score predicts progression in Parkinson's disease
Mov Disord, 31 (4), 487-90
DOI 10.1002/mds.26505, PubMed 26853697
Juvenile myasthenia gravis in Norway: A nationwide epidemiological study
Eur J Paediatr Neurol, 21 (2), 312-317
DOI 10.1016/j.ejpn.2016.09.001, PubMed 27666466
Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies
Stroke, 47 (6), 1479-85
DOI 10.1161/STROKEAHA.115.012382, PubMed 27165954
Exome sequencing of Pakistani consanguineous families identifies 30 novel candidate genes for recessive intellectual disability
Mol Psychiatry, 22 (11), 1604-1614
DOI 10.1038/mp.2016.109, PubMed 27457812
Depression in amyotrophic lateral sclerosis
Neurology, 86 (24), 2271-7
DOI 10.1212/WNL.0000000000002671, PubMed 27164661
A founder mutation p.H701P identified as a major cause of SPG7 in Norway
Eur J Neurol, 23 (4), 763-71
DOI 10.1111/ene.12937, PubMed 26756429
Single-Fiber Recordings of Nociceptive Fibers in Patients With HSAN Type V With Congenital Insensitivity to Pain
Clin J Pain, 32 (7), 636-42
DOI 10.1097/AJP.0000000000000303, PubMed 27270876
Bone mineral density in patients with multiple sclerosis, hereditary ataxia or hereditary spastic paraplegia after at least 10 years of disease - a case control study
BMC Neurol, 16 (1), 252
DOI 10.1186/s12883-016-0771-4, PubMed 27919248
High prevalence and increasing incidence of multiple sclerosis in the Norwegian county of Buskerud
Acta Neurol Scand, 135 (4), 412-418
DOI 10.1111/ane.12615, PubMed 27241360
Semiautomated Magnetic Resonance Imaging Assessment of Carotid Plaque Lipid Content
J Stroke Cerebrovasc Dis, 25 (8), 2004-10
DOI 10.1016/j.jstrokecerebrovasdis.2016.01.043, PubMed 27234919
Unstable carotid artery plaque: new insights and controversies in diagnostics and treatment
Croat Med J, 57 (4), 311-20
DOI 10.3325/cmj.2016.57.311, PubMed 27586546
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939
Major involvement of trunk muscles in myotonic dystrophy type 1
Acta Neurol Scand, 134 (6), 467-473
DOI 10.1111/ane.12565, PubMed 26984572
Major involvement of trunk muscles in myotonic dystrophy type 1
Acta Neurologica Scandinavica, 1, 1-7
DOI 10.1111/ane.12565, PublikaID 229
Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: pooled analysis of the INTERACT studies
J Neurol Neurosurg Psychiatry, 87 (12), 1330-1335
DOI 10.1136/jnnp-2016-313246, PubMed 27178897
Minocycline added to subcutaneous interferon β-1a in multiple sclerosis: randomized RECYCLINE study
Eur J Neurol, 23 (5), 861-70
DOI 10.1111/ene.12953, PubMed 26848561
Psychiatric disorders and psychological distress in patients undergoing evaluation for lung transplantation: a national cohort study
Gen Hosp Psychiatry, 42, 67-73
DOI 10.1016/j.genhosppsych.2016.07.001, PubMed 27638975
Titin antibodies in "seronegative" myasthenia gravis--A new role for an old antigen
J Neuroimmunol, 292, 108-15
DOI 10.1016/j.jneuroim.2016.01.018, PubMed 26943968
The Norwegian Cervical Arthroplasty Trial (NORCAT): 2-year clinical outcome after single-level cervical arthroplasty versus fusion-a prospective, single-blinded, randomized, controlled multicenter study
Eur Spine J, 26 (4), 1225-1235
DOI 10.1007/s00586-016-4922-5, PubMed 28012081
Heterotopic ossification and clinical outcome in nonconstrained cervical arthroplasty 2 years after surgery: the Norwegian Cervical Arthroplasty Trial (NORCAT)
Eur Spine J, 25 (7), 2271-8
DOI 10.1007/s00586-016-4549-6, PubMed 27061727
Does pain sensitivity change by migraine phase? A blinded longitudinal study
Cephalalgia, 37 (14), 1337-1349
DOI 10.1177/0333102416679955, PubMed 27919023
Optimal differentiation of high- and low-grade glioma and metastasis: a meta-analysis of perfusion, diffusion, and spectroscopy metrics
Neuroradiology, 58 (4), 339-50
DOI 10.1007/s00234-016-1642-9, PubMed 26767528
Assistive Technology for Cognition and Health-related Quality of Life in Huntington's Disease
J Huntingtons Dis, 5 (3), 261-270
DOI 10.3233/JHD-160210, PubMed 27689618
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
Mol Cell Neurosci, 77, 47-52
DOI 10.1016/j.mcn.2016.10.004, PubMed 27751903
Cerebral Microemboli Detection and Differentiation During Transcatheter Closure of Patent Ductus Arteriosus
Pediatr Cardiol, 37 (6), 1141-7
DOI 10.1007/s00246-016-1410-y, PubMed 27229332
Ambient Temperature and Stroke Occurrence: A Systematic Review and Meta-Analysis
Int J Environ Res Public Health, 13 (7)
DOI 10.3390/ijerph13070698, PubMed 27420077
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
Mult Scler, 22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Cognitive, Emotional, and Psychosocial Functioning of Girls Treated with Pharmacological Puberty Blockage for Idiopathic Central Precocious Puberty
Front Psychol, 7, 1053
DOI 10.3389/fpsyg.2016.01053, PubMed 27462292
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Sci Transl Med, 8 (333), 333ra50
DOI 10.1126/scitranslmed.aad6100, PubMed 27053774