Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Neurosurgery

55 publications found

Álvarez-Torres MDM, Juan-Albarracín J, Fuster-Garcia E, Bellvís-Bataller F, Lorente D, Reynés G, Font de Mora J, Aparici-Robles F, Botella C, Muñoz-Langa J, Faubel R, Asensio-Cuesta S, García-Ferrando GA, Chelebian E, Auger C, Pineda J, Rovira A, Oleaga L, Mollà-Olmos E, Revert AJ, Tshibanda L, Crisi G, Emblem KE, Martin D, Due-Tønnessen P et al. (2019)
Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study
J Magn Reson Imaging
DOI 10.1002/jmri.26958, PubMed 31654541

Baftiu A, Lima MH, Svendsen K, Larsson PG, Johannessen SI, Landmark CJ (2019)
Safety aspects of antiepileptic drugs-a population-based study of adverse effects relative to changes in utilisation
Eur J Clin Pharmacol, 75 (8), 1153-1160
DOI 10.1007/s00228-019-02678-1, PubMed 31001654

Bendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, Di Stefano G, Donnet A, Eide PK, Leal PRL, Maarbjerg S, May A, Nurmikko T, Obermann M, Jensen TS, Cruccu G (2019)
European Academy of Neurology guideline on trigeminal neuralgia
Eur J Neurol, 26 (6), 831-849
DOI 10.1111/ene.13950, PubMed 30860637

Blenkmann AO, Collavini S, Lubell J, Llorens A, Funderud I, Ivanovic J, Larsson PG, Meling TR, Bekinschtein T, Kochen S, Endestad T, Knight RT, Solbakk AK (2019)
Auditory deviance detection in the human insula: An intracranial EEG study
Cortex, 121, 189-200
DOI 10.1016/j.cortex.2019.09.002, PubMed 31629197

Bråten LCH, Rolfsen MP, Espeland A, Wigemyr M, Aßmus J, Froholdt A, Haugen AJ, Marchand GH, Kristoffersen PM, Lutro O, Randen S, Wilhelmsen M, Winsvold BS, Kadar TI, Holmgard TE, Vigeland MD, Vetti N, Nygaard ØP, Lie BA, Hellum C, Anke A, Grotle M, Schistad EI, Skouen JS, Grøvle L et al. (2019)
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
BMJ, 367, l5654
DOI 10.1136/bmj.l5654, PubMed 31619437

Cantalupo G, Pavlidis E, Beniczky S, Avanzini P, Gardella E, Larsson PG (2019)
Quantitative EEG analysis in Encephalopathy related to Status Epilepticus during slow Sleep
Epileptic Disord, 21 (S1), 31-40
DOI 10.1684/epd.2019.1055, PubMed 31149902

Corniola MV, Lemée JM, Da Broi M, Joswig H, Schaller K, Helseth E, Meling TR (2019)
Posterior fossa meningiomas: perioperative predictors of extent of resection, overall survival and progression-free survival
Acta Neurochir (Wien), 161 (5), 1003-1011
DOI 10.1007/s00701-019-03862-z, PubMed 30859321

Corniola MV, Lemée JM, Schaller K, Meling TR (2019)
Lateral sphenoid wing meningiomas without bone invasion-still skull base surgery?
Neurosurg Rev
DOI 10.1007/s10143-019-01181-6, PubMed 31664581

Edeklev CS, Halvorsen M, Løvland G, Vatnehol SAS, Gjertsen Ø, Nedregaard B, Sletteberg R, Ringstad G, Eide PK (2019)
Intrathecal Use of Gadobutrol for Glymphatic MR Imaging: Prospective Safety Study of 100 Patients
AJNR Am J Neuroradiol, 40 (8), 1257-1264
DOI 10.3174/ajnr.A6136, PubMed 31320462

Eide PK, Hansson HA (2019)
Blood-brain barrier leakage of blood proteins in idiopathic normal pressure hydrocephalus
Brain Res, 1727, 146547
DOI 10.1016/j.brainres.2019.146547, PubMed 31712085

Eide PK, Valnes LM, Pripp AH, Mardal KA, Ringstad G (2019)
Delayed clearance of cerebrospinal fluid tracer from choroid plexus in idiopathic normal pressure hydrocephalus
J Cereb Blood Flow Metab, UNSP 0271678X19874790
DOI 10.1177/0271678X19874790, PubMed 31495299

Feragen KB, Stock NM, Myhre A, Due-Tønnessen BJ (2019)
Medical Stress Reactions and Personal Growth in Parents of Children With a Rare Craniofacial Condition
Cleft Palate Craniofac J, 57 (2), 228-237
DOI 10.1177/1055665619869146, PubMed 31426676

Frič R, Eide PK (2019)
Chiari type 1-a malformation or a syndrome? A critical review
Acta Neurochir (Wien)
DOI 10.1007/s00701-019-04100-2, PubMed 31656982

Fric R, Ringstad G, Eide PK (2019)
Chiari malformation type 1- diagnostics and treatment
Tidsskr. Nor. Laegeforen., 139 (10), 931-935

Gardella E, Cantalupo G, Larsson PG, Fontana E, Bernardina BD, Rubboli G, Darra F (2019)
EEG features in Encephalopathy related to Status Epilepticus during slow Sleep
Epileptic Disord, 21 (S1), 22-30
DOI 10.1684/epd.2019.1054, PubMed 31162114

Hasan-Olive MM, Enger R, Hansson HA, Nagelhus EA, Eide PK (2019)
Pathological mitochondria in neurons and perivascular astrocytic endfeet of idiopathic normal pressure hydrocephalus patients
Fluids Barriers CNS, 16 (1), 39
DOI 10.1186/s12987-019-0160-7, PubMed 31849332

Hasan-Olive MM, Hansson HA, Enger R, Nagelhus EA, Eide PK (2019)
Blood-Brain Barrier Dysfunction in Idiopathic Intracranial Hypertension
J Neuropathol Exp Neurol, 78 (9), 808-818
DOI 10.1093/jnen/nlz063, PubMed 31393574

Haug Nordenmark T, Karic T, Røe C, Sorteberg W, Sorteberg A (2019)
The post-aSAH syndrome: a self-reported cluster of symptoms in patients with aneurysmal subarachnoid hemorrhage
J Neurosurg, 1-10 (in press)
DOI 10.3171/2019.1.JNS183168, PubMed 31003212

Helseth Ø, Lied B, Heskestad B, Ekseth K, Helseth E (2019)
Retrospective single-centre series of 1300 consecutive cases of outpatient cervical spine surgery: complications, hospital readmissions, and reoperations
Br J Neurosurg, 33 (6), 613-619
DOI 10.1080/02688697.2019.1675587, PubMed 31607163

Hough D, Robinson JE, Bellingham M, Fleming LM, McLaughlin M, Jama K, Haraldsen I, Solbakk AK, Evans NP (2019)
Peripubertal GnRH and testosterone co-treatment leads to increased familiarity preferences in male sheep
Psychoneuroendocrinology, 108, 70-77
DOI 10.1016/j.psyneuen.2019.06.008, PubMed 31229635

Hvinden IC, Berg HE, Sachse D, Skaga E, Skottvoll FS, Lundanes E, Sandberg CJ, Vik-Mo EO, Rise F, Wilson SR (2019)
Nuclear Magnetic Resonance Spectroscopy to Identify Metabolite Biomarkers of Nonresponsiveness to Targeted Therapy in Glioblastoma Tumor Stem Cells
J Proteome Res, 18 (5), 2012-2020
DOI 10.1021/acs.jproteome.8b00801, PubMed 30964684

Jacobsen HH, Ringstad G, Jørstad ØK, Moe MC, Sandell T, Eide PK (2019)
The Human Visual Pathway Communicates Directly With the Subarachnoid Space
Invest Ophthalmol Vis Sci, 60 (7), 2773-2780
DOI 10.1167/iovs.19-26997, PubMed 31247084

Kam JWY, Lin JJ, Solbakk AK, Endestad T, Larsson PG, Knight RT (2019)
Default network and frontoparietal control network theta connectivity supports internal attention
Nat Hum Behav, 3 (12), 1263-1270
DOI 10.1038/s41562-019-0717-0, PubMed 31477910

Kogelman LJA, Esserlind AL, Christensen AF, Awasthi S, Ripke S, Ingason A, Davidsson OB, Erikstrup C, Hjalgrim H, Ullum H, Olesen J, Hansen TF, Gudbjartsson D, Gastafsson O, Stefansson K, Stefansson H, Porsteinsdottir U, Andersen S, Banasik K, Brunak S, Buil A, Burgdorf K, Gregor J, Jennum P, Nielsen KR et al. (2019)
Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Neurol.-Genet., 5 (6), e364

Kristoffersen ES, Faiz KW, Winsvold BS (2019)
Neurology residents' knowledge of the management of headache
Cephalalgia, 39 (11), 1396-1406
DOI 10.1177/0333102419847973, PubMed 31067081

Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Cade BE, Haas M, Kathiresan S, Little MA, Luik AI, Loudon AS, Purcell S, Richmond RC, Scheer FAJL, Schormair B et al. (2019)
Biological and clinical insights from genetics of insomnia symptoms
Nat Genet, 51 (3), 387-393
DOI 10.1038/s41588-019-0361-7, PubMed 30804566

Langvatn EA, Frič R, Due-Tønnessen BJ, Eide PK (2019)
Intracranial volume versus static and pulsatile intracranial pressure values in children with craniosynostosis
J Neurosurg Pediatr, 24 (1), 66-74
DOI 10.3171/2019.2.PEDS18767, PubMed 31003225

Lashkarivand A, Ringstad G, Eide PK (2019)
Surgery for Brainstem Cavernous Malformations: Association between Preoperative Grade and Postoperative Quality of Life
Oper Neurosurg (Hagerstown) (in press)
DOI 10.1093/ons/opz337, PubMed 31768544

Latysheva A, Emblem KE, Brandal P, Vik-Mo EO, Pahnke J, Røysland K, Hald JK, Server A (2019)
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology, 61 (5), 545-555
DOI 10.1007/s00234-019-02173-5, PubMed 30712139

Lemée JM, Corniola MV, Da Broi M, Joswig H, Scheie D, Schaller K, Helseth E, Meling TR (2019)
Extent of Resection in Meningioma: Predictive Factors and Clinical Implications
Sci Rep, 9 (1), 5944
DOI 10.1038/s41598-019-42451-z, PubMed 30976047

Lemée JM, Corniola MV, Da Broi M, Schaller K, Meling TR (2019)
Early Postoperative Complications in Meningioma: Predictive Factors and Impact on Outcome
World Neurosurg, 128, e851-e858
DOI 10.1016/j.wneu.2019.05.010, PubMed 31082552

Lemée JM, Joswig H, Da Broi M, Corniola MV, Scheie D, Schaller K, Helseth E, Meling TR (2019)
WHO grade I meningiomas: classification-tree for prognostic factors of survival
Neurosurg Rev (in press)
DOI 10.1007/s10143-019-01117-0, PubMed 31183587

Lundar T, Due-Tønnessen BJ (2019)
Persistent shunt dependency in children treated with CSF diversion for idiopathic intracranial hypertension (IIH)
Acta Neurochir (Wien), 162 (1), 39-42
DOI 10.1007/s00701-019-04142-6, PubMed 31736001

Lundar T, Due-Tønnessen BJ, Frič R, Brandal P, Stensvold E, Due-Tønnessen P (2019)
Adult outcome after neurosurgical treatment of brain tumours in the first year of life: long-term follow-up of a single consecutive institutional series of 34 patients
Acta Neurochir (Wien), 161 (9), 1793-1798
DOI 10.1007/s00701-019-04014-z, PubMed 31309304

Lundar T, Due-Tønnessen BJ, Frič R, Krossnes B, Brandal P, Stensvold E, Due-Tønnessen P (2019)
Neurosurgical treatment of pediatric pleomorphic xanthoastrocytomas: long-term follow-up of a single-institution, consecutive series of 12 patients
J Neurosurg Pediatr, 23 (4), 512-516
DOI 10.3171/2018.11.PEDS18449, PubMed 30738389

Meling TR, Da Broi M, Scheie D, Helseth E, Smoll NR (2019)
Meningioma Surgery-Are We Making Progress?
World Neurosurg, 125, e205-e213
DOI 10.1016/j.wneu.2019.01.042, PubMed 30684722

Meling TR, Patet G (2019)
What is the best therapeutic approach to a pediatric patient with a deep-seated brain AVM?
Neurosurg Rev, 42 (2), 409-416
DOI 10.1007/s10143-019-01101-8, PubMed 30980204

Meling TR, Patet G (2019)
Clip-wrapping of ruptured blood blister-like aneurysms of the internal carotid artery
Neurosurg Rev (in press)
DOI 10.1007/s10143-019-01172-7, PubMed 31485789

Mouthaan BE, Rados M, Boon P, Carrette E, Diehl B, Jung J, Kimiskidis V, Kobulashvili T, Kuchukhidze G, Larsson PG, Leitinger M, Ryvlin P, Rugg-Gunn F, Seeck M, Vulliémoz S, Huiskamp G, Leijten FSS, Van Eijsden P, Trinka E, Braun KPJ, E-PILEPSY consortium (2019)
Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: A systematic review from the E-PILEPSY consortium
Clin Neurophysiol, 130 (5), 845-855
DOI 10.1016/j.clinph.2018.12.016, PubMed 30824202

Puhr A, Ruud E, Anderson V, Due-Tønnessen BJ, Skarbø AB, Finset A, Andersson S (2019)
Social attainment in physically well-functioning long-term survivors of pediatric brain tumour; the role of executive dysfunction, fatigue, and psychological and emotional symptoms
Neuropsychol Rehabil
DOI 10.1080/09602011.2019.1677480, PubMed 31603026

Robertsen A, Helseth E, Laake JH, Førde R (2019)
Neurocritical care physicians' doubt about whether to withdraw life-sustaining treatment the first days after devastating brain injury: an interview study
Scand J Trauma Resusc Emerg Med, 27 (1), 81
DOI 10.1186/s13049-019-0648-9, PubMed 31462245

Sadaghiani S, Dombert PL, Løvstad M, Funderud I, Meling TR, Endestad T, Knight RT, Solbakk AK, D'Esposito M (2019)
Lesions to the Fronto-Parietal Network Impact Alpha-Band Phase Synchrony and Cognitive Control
Cereb Cortex, 29 (10), 4143-4153
DOI 10.1093/cercor/bhy296, PubMed 30535068

Skaga E, Kulesskiy E, Brynjulvsen M, Sandberg CJ, Potdar S, Langmoen IA, Laakso A, Gaál-Paavola E, Perola M, Wennerberg K, Vik-Mo EO (2019)
Feasibility study of using high-throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment
Clin Transl Med, 8 (1), 33
DOI 10.1186/s40169-019-0253-6, PubMed 31889236

Skaga E, Kulesskiy E, Fayzullin A, Sandberg CJ, Potdar S, Kyttälä A, Langmoen IA, Laakso A, Gaál-Paavola E, Perola M, Wennerberg K, Vik-Mo EO (2019)
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naïve glioblastoma
BMC Cancer, 19 (1), 628
DOI 10.1186/s12885-019-5861-4, PubMed 31238897

Skaga E, Skaga IØ, Grieg Z, Sandberg CJ, Langmoen IA, Vik-Mo EO (2019)
The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy
J Cancer Res Clin Oncol, 145 (6), 1495-1507
DOI 10.1007/s00432-019-02920-4, PubMed 31028540

Skodvin TØ, Evju Ø, Sorteberg A, Isaksen JG (2019)
Prerupture Intracranial Aneurysm Morphology in Predicting Risk of Rupture: A Matched Case-Control Study
Neurosurgery, 84 (1), 132-140
DOI 10.1093/neuros/nyy010, PubMed 29529238

Sorteberg A, Bredmose PP, Hansen AE, Sorteberg W (2019)
The path from ictus to Neurosurgery: chronology and transport logistics of patients with aneurysmal subarachnoid haemorrhage in the South-Eastern Norway Health Region
Acta Neurochir (Wien), 161 (8), 1497-1506
DOI 10.1007/s00701-019-03971-9, PubMed 31197472

Stensvold E, Myklebust TÅ, Cappelen J, Due-Tønnessen BJ, Due-Tønnessen P, Kepka A, Johannesen TB, Krossnes B, Lundar T, Maric S, Miletic H, Moholdt V, Myrmel KS, Nordberg T, Rydland J, Stokland T, Solem K, Solheim O, Torsvik I, Wikran GC, Zeller B, Wesenberg F, Bechensteen AG, Brandal P (2019)
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Pediatr Blood Cancer, 66 (10), e27910
DOI 10.1002/pbc.27910, PubMed 31264356

Tornås S, Løvstad M, Solbakk AK, Schanke AK, Stubberud J (2019)
Use It or Lose It? A 5-Year Follow-up Study of Goal Management Training in Patients with Acquired Brain Injury
J Int Neuropsychol Soc, 25 (10), 1082-1087
DOI 10.1017/S1355617719000626, PubMed 31232252

Ulvin LB, Taubøll E, Olsen KB, Heuser K (2019)
Predictive performances of STESS and EMSE in a Norwegian adult status epilepticus cohort
Seizure, 70, 6-11
DOI 10.1016/j.seizure.2019.06.024, PubMed 31229856

Vinje V, Ringstad G, Lindstrøm EK, Valnes LM, Rognes ME, Eide PK, Mardal KA (2019)
Respiratory influence on cerebrospinal fluid flow - a computational study based on long-term intracranial pressure measurements
Sci Rep, 9 (1), 9732
DOI 10.1038/s41598-019-46055-5, PubMed 31278278

Wang H, Lane JM, Jones SE, Dashti HS, Ollila HM, Wood AR, van Hees VT, Brumpton B, Winsvold BS, Kantojärvi K, Palviainen T, Cade BE, Sofer T, Song Y, Patel K, Anderson SG, Bechtold DA, Bowden J, Emsley R, Kyle SD, Little MA, Loudon AS, Scheer FAJL, Purcell SM, Richmond RC et al. (2019)
Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes
Nat Commun, 10 (1), 3503
DOI 10.1038/s41467-019-11456-7, PubMed 31409809

Zahl SM, Egge A, Helseth E, Wester K (2019)
Clinical, Radiological, and Demographic Details of Benign External Hydrocephalus: A Population-Based Study
Pediatr Neurol, 96, 53-57
DOI 10.1016/j.pediatrneurol.2019.01.015, PubMed 30808532

Züchner M, Lervik A, Kondratskaya E, Bettembourg V, Zhang L, Haga HA, Boulland JL (2019)
Development of a Multimodal Apparatus to Generate Biomechanically Reproducible Spinal Cord Injuries in Large Animals
Front Neurol, 10, 223
DOI 10.3389/fneur.2019.00223, PubMed 30941086

Aamodt AH, Bjork MH, Alstadhaug KB, Eldoen G, Dueland AN, Poole T, Hagen K, Vetvik KG, Ofte HK, Sonnervik J, Kristoffersen ES, Winsvold BS, Lundqvist C, Sagabraten SO (2019)
Practical management of headache
Tidsskr. Nor. Laegeforen., 139 (7), 617-620

 
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