Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2016 from OUS - Department of Infectious Diseases

32 publications found

Bains SJ, Mahic M, Myklebust TÅ, Småstuen MC, Yaqub S, Dørum LM, Bjørnbeth BA, Møller B, Brudvik KW, Taskén K (2016)
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
J Clin Oncol, 34 (21), 2501-8
DOI 10.1200/JCO.2015.65.3519, PubMed 27247217

Bates M, Brantsaeter AB (2016)
Human cytomegalovirus (CMV) in Africa: a neglected but important pathogen
J Virus Erad, 2 (3), 136-42
PubMed 27482452

Bustinduy AL, Friedman JF, Kjetland EF, Ezeamama AE, Kabatereine NB, Stothard JR, King CH (2016)
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis
PLoS Negl Trop Dis, 10 (9), e0004946
DOI 10.1371/journal.pntd.0004946, PubMed 27658198

Baan M, Galappaththi-Arachchige HN, Gagai S, Aurlund CG, Vennervald BJ, Taylor M, van Lieshout L, Kjetland EF (2016)
The Accuracy of Praziquantel Dose Poles for Mass Treatment of Schistosomiasis in School Girls in KwaZulu-Natal, South Africa
PLoS Negl Trop Dis, 10 (5), e0004623
DOI 10.1371/journal.pntd.0004623, PubMed 27139497

Dukic AR, McClymont DW, Taskén K (2016)
A Cell-Based High-Throughput Assay for Gap Junction Communication Suitable for Assessing Connexin 43-Ezrin Interaction Disruptors Using IncuCyte ZOOM
SLAS Discov, 22 (1), 77-85
DOI 10.1177/1087057116669120, PubMed 27628689

Eliassen KE, Berild D, Reiso H, Grude N, Christophersen KS, Finckenhagen C, Lindbæk M (2016)
Incidence and antibiotic treatment of erythema migrans in Norway 2005-2009
Ticks Tick Borne Dis, 8 (1), 1-8
DOI 10.1016/j.ttbdis.2016.06.006, PubMed 27475874

Galappaththi-Arachchige HN, Amlie Hegertun IE, Holmen S, Qvigstad E, Kleppa E, Sebitloane M, Ndhlovu PD, Vennervald BJ, Gundersen SG, Taylor M, Kjetland EF (2016)
Association of Urogenital Symptoms with History of Water Contact in Young Women in Areas Endemic for S. haematobium. A Cross-Sectional Study in Rural South Africa
Int J Environ Res Public Health, 13 (11)
DOI 10.3390/ijerph13111135, PubMed 27854250

Gautret P, Mockenhaupt F, Grobusch MP, Rothe C, von Sonnenburg F, van Genderen PJ, Chappuis F, Asgeirsson H, Caumes E, Bottieau E, Malvy D, Lopez-Vélez R, Jensenius M, Larsen CS, Castelli F, Rapp C, Field V, Molina I, Gkrania-Klotsas E, Florescu S, Lalloo D, Schlagenhauf P (2016)
Arboviral and other illnesses in travellers returning from Brazil, June 2013 to May 2016: implications for the 2016 Olympic and Paralympic Games
Euro Surveill, 21 (27)
DOI 10.2807/1560-7917.ES.2016.21.27.30278, PubMed 27416907

Haissman JM, Knudsen A, Hoel H, Kjær A, Kristoffersen US, Berge RK, Katzenstein TL, Svardal A, Ueland T, Aukrust P, Lebech AM, Nielsen SD, Trøseid M (2016)
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection
J Acquir Immune Defic Syndr, 71 (2), 130-6
DOI 10.1097/QAI.0000000000000843, PubMed 26413854

Holmen S, Galappaththi-Arachchige HN, Kleppa E, Pillay P, Naicker T, Taylor M, Onsrud M, Kjetland EF, Albregtsen F (2016)
Characteristics of Blood Vessels in Female Genital Schistosomiasis: Paving the Way for Objective Diagnostics at the Point of Care
PLoS Negl Trop Dis, 10 (4), e0004628
DOI 10.1371/journal.pntd.0004628, PubMed 27073857

Jensenius M, Winje BA, Blomberg B, Mengshoel AT, Lippe Bv, Hannula R, Bruun JN, Knudsen PK, Rønning JO, Heldal E, Dyrhol-Riise AM (2016)
Multidrug-resistant tuberculosis in Norway: a nationwide study, 1995-2014
Int J Tuberc Lung Dis, 20 (6), 786-92
DOI 10.5588/ijtld.15.0895, PubMed 27155182

Jenum S, Bakken R, Dhanasekaran S, Mukherjee A, Lodha R, Singh S, Singh V, Haks MC, Ottenhoff TH, Kabra SK, Doherty TM, Ritz C, Grewal HM (2016)
BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome
Sci Rep, 6, 38841
DOI 10.1038/srep38841, PubMed 27941850

Jenum S, Dhanasekaran S, Ritz C, Macaden R, Doherty TM, Grewal HM, TB Trials Study Group (2016)
Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis: Specific Immunity in Young Children
Pediatr Infect Dis J, 35 (12), 1336-1338
DOI 10.1097/INF.0000000000001328, PubMed 27642776

Jespersen S, Pedersen KK, Anesten B, Zetterberg H, Fuchs D, Gisslén M, Hagberg L, Trøseid M, Nielsen SD (2016)
Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
BMC Infect Dis, 16, 176
DOI 10.1186/s12879-016-1510-6, PubMed 27103116

Kodogo V, Zhou DT, Oektedalen O, Duri K, Stray-Pedersen B, Gomo E (2016)
Apolipoprotein B Gene Polymorphisms and Dyslipidemia in HIV Infected Adult Zimbabweans
Open AIDS J, 10, 190-198
DOI 10.2174/1874613601610010190, PubMed 27790293

Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Taskén K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Béziat V (2016)
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Cell Rep, 15 (5), 1088-1099
DOI 10.1016/j.celrep.2016.04.005, PubMed 27117418

Midgard H, Bjøro B, Mæland A, Konopski Z, Kileng H, Damås JK, Paulsen J, Heggelund L, Sandvei PK, Ringstad JO, Karlsen LN, Stene-Johansen K, Pettersson JH, Dorenberg DH, Dalgard O (2016)
Hepatitis C reinfection after sustained virological response
J Hepatol, 64 (5), 1020-1026
DOI 10.1016/j.jhep.2016.01.001, PubMed 26780289

Moltu K, Henjum K, Oberprieler NG, Bjørnbeth BA, Taskén K (2016)
Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2
Hum Immunol, 78 (2), 129-137
DOI 10.1016/j.humimm.2016.10.007, PubMed 27769746

Nielsen HG, Øktedalen O, Opstad PK, Lyberg T (2016)
Plasma Cytokine Profiles in Long-Term Strenuous Exercise
J Sports Med (Hindawi Publ Corp), 2016, 7186137
DOI 10.1155/2016/7186137, PubMed 27239554

Pillay P, van Lieshout L, Taylor M, Sebitloane M, Zulu SG, Kleppa E, Roald B, Kjetland EF (2016)
Cervical cytology as a diagnostic tool for female genital schistosomiasis: Correlation to cervical atypia and Schistosoma polymerase chain reaction
Cytojournal, 13, 10
DOI 10.4103/1742-6413.180784, PubMed 27168759

Prebensen C, Lind A, Dyrhol-Riise AM, Kvale D (2016)
Regulation of Gag- and Env-Specific CD8+ T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy
PLoS One, 11 (4), e0153849
DOI 10.1371/journal.pone.0153849, PubMed 27128502

Sisay Z, Djikeng A, Berhe N, Belay G, Abegaz WE, Wang QH, Saif LJ (2016)
First detection and molecular characterization of sapoviruses and noroviruses with zoonotic potential in swine in Ethiopia
Arch Virol, 161 (10), 2739-47
DOI 10.1007/s00705-016-2974-9, PubMed 27424025

Stene-Johansen K, Yaqoob N, Overbo J, Aberra H, Desalegn H, Berhe N, Johannessen A (2016)
Dry Blood Spots a Reliable Method for Measurement of Hepatitis B Viral Load in Resource-Limited Settings
PLoS One, 11 (11), e0166201
DOI 10.1371/journal.pone.0166201, PubMed 27820845

Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
J Acquir Immune Defic Syndr, 73 (2), 138-48
DOI 10.1097/QAI.0000000000001080, PubMed 27632144

Stubhaug TT, Reiakvam OM, Stensvold CR, Hermansen NO, Holberg-Petersen M, Antal EA, Gaustad K, Førde IS, Heger B (2016)
Fatal primary amoebic meningoencephalitis in a Norwegian tourist returning from Thailand
JMM Case Rep, 3 (3), e005042
DOI 10.1099/jmmcr.0.005042, PubMed 28348761

Tonby K, Wergeland I, Lieske NV, Kvale D, Tasken K, Dyrhol-Riise AM (2016)
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
BMC Infect Dis, 16 (1), 599
DOI 10.1186/s12879-016-1938-8, PubMed 27776487

Uyeki TM, Mehta AK, Davey RT, Liddell AM, Wolf T, Vetter P, Schmiedel S, Grünewald T, Jacobs M, Arribas JR, Evans L, Hewlett AL, Brantsaeter AB, Ippolito G, Rapp C, Hoepelman AI, Gutman J, Working Group of the U.S.–European Clinical Network on Clinical Management of Ebola Virus Disease Patients in the U.S. and Europe (2016)
Clinical Management of Ebola Virus Disease in the United States and Europe
N Engl J Med, 374 (7), 636-46
DOI 10.1056/NEJMoa1504874, PubMed 26886522

Wehbi VL, Taskén K (2016)
Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units
Front Immunol, 7, 222
DOI 10.3389/fimmu.2016.00222, PubMed 27375620

Wergeland I, Assmus J, Dyrhol-Riise AM (2016)
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
PLoS One, 11 (9), e0163848
DOI 10.1371/journal.pone.0163848, PubMed 27685462

Waagsbø B, Svardal A, Ueland T, Landrø L, Øktedalen O, Berge RK, Flo TH, Aukrust P, Damås JK (2016)
Low levels of short- and medium-chain acylcarnitines in HIV-infected patients
Eur J Clin Invest, 46 (5), 408-17
DOI 10.1111/eci.12609, PubMed 26913383

Zhou DT, Nehumba D, Oktedalen O, Marange P, Kodogo V, Gomo ZA, Esterhuizen TM, Stray-Pedersen B (2016)
Changes in Lipid Profiles of HIV(+) Adults over Nine Months at a Harare HIV Clinic: A Longitudinal Study
Biochem Res Int, 2016, 3204818
DOI 10.1155/2016/3204818, PubMed 27051532

Zhou DT, Oektedalen O, Shawarira-Bote S, Stray-Pedersen B (2016)
Changes in coronary heart disease risk profiles of HIV patients in Zimbabwe over 9 months: a follow-up study
HIV AIDS (Auckl), 8, 165-174
DOI 10.2147/HIV.S113206, PubMed 27822124

 
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