Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2019 from OUS - Department of Geriatric Medicine
72 publications found
Anxiety symptom levels are persistent in older adults with a mental disorder: A 33-month follow-up study
Int J Geriatr Psychiatry, 34 (4), 601-608
DOI 10.1002/gps.5058, PubMed 30609143
The effect of psychosocial support on caregivers' perceived criticism and emotional over-involvement of persons with dementia: an assessor-blinded randomized controlled trial
BMC Health Serv Res, 19 (1), 744
DOI 10.1186/s12913-019-4551-x, PubMed 31651321
Implementation fidelity in a complex intervention promoting psychosocial well-being following stroke: an explanatory sequential mixed methods study
BMC Med Res Methodol, 19 (1), 59
DOI 10.1186/s12874-019-0694-z, PubMed 30876403
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Transl Psychiatry, 9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Arti Hurria and the progress in integrating the geriatric assessment into oncology: Young International Society of Geriatric Oncology review paper
J Geriatr Oncol, 11 (2), 203-211
DOI 10.1016/j.jgo.2019.08.005, PubMed 31451439
Drug Use before and after Initiating Treatment with Acetylcholinesterase Inhibitors
Dement Geriatr Cogn Dis Extra, 9 (1), 196-206
DOI 10.1159/000497307, PubMed 31143200
Employment and attendance in day care centres for people with mild intellectual disabilities - do age, gender, functional level or hospital admissions matter?
J Intellect Disabil Res, 64 (3), 197-208
DOI 10.1111/jir.12709, PubMed 31850647
Delirium motor subtypes and prognosis in hospitalized geriatric patients - A prospective observational study
J Psychosom Res, 122, 24-28
DOI 10.1016/j.jpsychores.2019.04.020, PubMed 31126407
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0578, PubMed 30917648
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr. Nor. Laegeforen., 139 (6), 517-520
Adaptive Computerized Working Memory Training in Patients With Mild Cognitive Impairment. A Randomized Double-Blind Active Controlled Trial
Front Psychol, 10, 807
DOI 10.3389/fpsyg.2019.00807, PubMed 31031677
B-Lymphocyte Depletion in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Ann Intern Med, 170 (9), 585-593
DOI 10.7326/M18-1451, PubMed 30934066
Drug use differs by care level. A cross-sectional comparison between older people living at home or in a nursing home in Oslo, Norway
BMC Geriatr, 19 (1), 49
DOI 10.1186/s12877-019-1064-8, PubMed 30782115
Gender-specific mediators of the association between parental education and adiposity among adolescents: the HEIA study
Sci Rep, 9 (1), 7282
DOI 10.1038/s41598-019-43604-w, PubMed 31086277
Associations Between Adherence to the Physical Activity and Exercise Program Applied in the LAST Study and Functional Recovery After Stroke
Arch Phys Med Rehabil, 100 (12), 2251-2259
DOI 10.1016/j.apmr.2019.04.023, PubMed 31374191
Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study
Vasc Health Risk Manag, 15, 11-18
DOI 10.2147/VHRM.S191873, PubMed 30799926
Predictors for Favorable Cognitive Outcome Post-Stroke: A-Seven-Year Follow-Up Study
Dement Geriatr Cogn Disord, 48 (1-2), 45-55
DOI 10.1159/000501850, PubMed 31461703
Applicability of the locus of control of behaviour scale for people with dementia
Aging Ment Health, 24 (12), 2111-2116
DOI 10.1080/13607863.2019.1652244, PubMed 31402698
Optimizing the geriatrician's contribution to cancer care for older patients
J Geriatr Oncol, 11 (3), 389-394
DOI 10.1016/j.jgo.2019.06.018, PubMed 31285173
Effect of a dialogue-based intervention on psychosocial well-being 6 months after stroke in Norway: A randomized controlled trial
J Rehabil Med, 51 (8), 557-565
DOI 10.2340/16501977-2585, PubMed 31411337
The General Health Questionnaire-28 (GHQ-28) as an outcome measurement in a randomized controlled trial in a Norwegian stroke population
BMC Psychol, 7 (1), 18
DOI 10.1186/s40359-019-0293-0, PubMed 30902115
The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial
Int J Geriatr Psychiatry, 34 (7), 974-981
DOI 10.1002/gps.5098, PubMed 30901487
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study
J Alzheimers Dis, 67 (1), 197-210
DOI 10.3233/JAD-180479, PubMed 30530973
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study
J Alzheimers Dis, 71 (4), 1381
DOI 10.3233/JAD-199007, PubMed 31524177
Quality of life of family carers of persons with young-onset compared to late-onset dementia
Aging Ment Health, 24 (9), 1394-1401
DOI 10.1080/13607863.2019.1617245, PubMed 31106576
Quality of life of family carers of persons with young-onset dementia: A Nordic two-year observational multicenter study
PLoS One, 14 (7), e0219859
DOI 10.1371/journal.pone.0219859, PubMed 31323066
A physical activity intervention to prevent cognitive decline after stroke: Secondary results from the Life After STroke study, an 18-month randomized controlled trial
J Rehabil Med, 51 (9), 646-651
DOI 10.2340/16501977-2588, PubMed 31440765
Carotid Atherosclerosis and Cognitive Function in a General Population Aged 63-65 Years: Data from the Akershus Cardiac Examination (ACE) 1950 Study
J Alzheimers Dis, 70 (4), 1041-1049
DOI 10.3233/JAD-190327, PubMed 31306128
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Is there equity in initial access to formal dementia care in Europe? The Andersen Model applied to the Actifcare cohort
Int J Geriatr Psychiatry, 35 (1), 45-52
DOI 10.1002/gps.5213, PubMed 31647572
Resilience in Carers of People With Young-Onset Alzheimer Disease
J Geriatr Psychiatry Neurol, 32 (2), 59-67
DOI 10.1177/0891988718824039, PubMed 30651027
Modifiable factors affecting older patients' quality of life and physical function during cancer treatment
J Geriatr Oncol, 10 (6), 904-912
DOI 10.1016/j.jgo.2019.08.001, PubMed 31444088
Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study
Palliat Med, 33 (3), 312-322
DOI 10.1177/0269216319825972, PubMed 30712456
Finding the Way Forward: The Lived Experience of People With Stroke After Participation in a Complex Psychosocial Intervention
Qual Health Res, 29 (12), 1711-1724
DOI 10.1177/1049732319833366, PubMed 30862270
The Effect of Changing the Amyloid β42 Cut-off of Cerebrospinal Fluid Biomarkers on Alzheimer Disease Diagnosis in a Memory Clinic Population in Norway
Alzheimer Dis Assoc Disord, 33 (1), 72-74
DOI 10.1097/WAD.0000000000000268, PubMed 30106756
Posterior circulation stroke diagnosis using HINTS in patients presenting with acute vestibular syndrome: A systematic review
Eur Stroke J, 4 (3), 233-239
DOI 10.1177/2396987319843701, PubMed 31984230
A physical activity program is no more effective than standard care at maintaining upper limb activity in community-dwelling people with stroke: secondary outcomes from a randomized trial
Clin Rehabil, 33 (10), 1607-1613
DOI 10.1177/0269215519856048, PubMed 31198048
Music Therapy and Physical Activity to Ease Anxiety, Restlessness, Irritability, and Aggression in Individuals With Dementia With Signs of Frontotemporal Lobe Degeneration
J Psychosoc Nurs Ment Health Serv, 57 (5), 29-37
DOI 10.3928/02793695-20190124-02, PubMed 30753735
Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward
PLoS One, 14 (7), e0220071
DOI 10.1371/journal.pone.0220071, PubMed 31329634
Study protocol: ASCRIBED: the impact of Acute SystematiC inflammation upon cerebRospinal fluId and blood BiomarkErs of brain inflammation and injury in dementia: a study in acute hip fracture patients
BMC Neurol, 19 (1), 223
DOI 10.1186/s12883-019-1447-7, PubMed 31493787
The study protocol for a randomized, controlled trial of acupuncture versus a sham procedure versus standard care alone for the treatment of delirium in acutely hospitalized older adults with a medical illness
Maturitas, 124, 72-80
DOI 10.1016/j.maturitas.2019.03.001, PubMed 31097183
Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome
Physiol Rep, 7 (11), e14138
DOI 10.14814/phy2.14138, PubMed 31161646
Relationship quality and sense of coherence in dementia: Results of a European cohort study
Int J Geriatr Psychiatry, 34 (5), 745-755
DOI 10.1002/gps.5082, PubMed 30729572
The effect of anxiety on cognition in older adult inpatients with depression: results from a multicenter observational study
Heliyon, 5 (8), e02235
DOI 10.1016/j.heliyon.2019.e02235, PubMed 31497664
Blood pressure variability in hypertensive patients with atrial fibrillation in the VALUE trial
Blood Press, 28 (2), 77-83
DOI 10.1080/08037051.2018.1524707, PubMed 30614275
GOSAFE - Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery: early analysis on 977 patients
J Geriatr Oncol, 11 (2), 244-255
DOI 10.1016/j.jgo.2019.06.017, PubMed 31492572
Amyloid-β PET-Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic
PLoS One, 14 (8), e0221365
DOI 10.1371/journal.pone.0221365, PubMed 31430334
Oscillatory connectivity as a diagnostic marker of dementia due to Alzheimer's disease
Clin Neurophysiol, 130 (10), 1889-1899
DOI 10.1016/j.clinph.2019.07.016, PubMed 31408790
Delirium screening in an acute geriatric ward by nurses using 4AT: results from a quality improvement project
Eur. Geriatr. Med., 10 (4), 667-671
Structured follow-up of frail home-dwelling older people in primary health care: is there a special need, and could a checklist be of any benefit? A qualitative study of experiences from registered nurses and their leaders
J Multidiscip Healthc, 12, 675-690
DOI 10.2147/JMDH.S212283, PubMed 31686832
Autonomic cardiovascular control in older patients with acute infection and delirium: a pilot study of orthostatic stress responses
BMC Geriatr, 19 (1), 23
DOI 10.1186/s12877-019-1035-0, PubMed 30683068
Aging With a Physical Disability, Duration of Disability, and Life Satisfaction: A 5-Year Longitudinal Study Among People Aged 40 to 79 Years
Int J Aging Hum Dev, 91 (3), 253-273
DOI 10.1177/0091415019857061, PubMed 31237142
A validation study of the ICECAP-O in informal carers of people with dementia from eight European Countries
Qual Life Res, 29 (1), 237-251
DOI 10.1007/s11136-019-02317-3, PubMed 31595452
Atrial fibrillation in cryptogenic stroke and transient ischaemic attack - The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Rationale and design
Eur Stroke J, 4 (2), 172-180
DOI 10.1177/2396987319837089, PubMed 31259265
Brain age prediction in stroke patients: Highly reliable but limited sensitivity to cognitive performance and response to cognitive training
Neuroimage Clin, 25, 102159
DOI 10.1016/j.nicl.2019.102159, PubMed 31927499
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Sci Rep, 9 (1), 7013
DOI 10.1038/s41598-019-43458-2, PubMed 31065058
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period
Eur J Surg Oncol, 46 (3), 310-315
DOI 10.1016/j.ejso.2019.07.027, PubMed 31378416
Interventions to enhance access to and utilization of formal community care services for home dwelling persons with dementia and their informal carers. A scoping review
Aging Ment Health, 24 (2), 200-211
DOI 10.1080/13607863.2018.1523876, PubMed 30663890
The Loss in Expectation of Life due to Early-Onset Mild Cognitive Impairment and Early-Onset Dementia in Norway
Dement Geriatr Cogn Disord, 47 (4-6), 355-365
DOI 10.1159/000501269, PubMed 31319412
Pain is associated with reduced quality of life and functional status in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Scand J Pain, 19 (1), 61-72
DOI 10.1515/sjpain-2018-0095, PubMed 30325738
Facilitation of activities for people with dementia in day care: a qualitative study exploring the experiences of staff
J Multidiscip Healthc, 12, 503-513
DOI 10.2147/JMDH.S198024, PubMed 31308683
Nursing Staff's Knowledge and Attitudes toward Dementia: A Pilot Study from an Indian Perspective
Dement Geriatr Cogn Dis Extra, 9 (3), 352-361
DOI 10.1159/000502770, PubMed 31616459
Subjective memory impairment, instrumental activities of daily living and longitudinal effect on mortality among older adults in a population-based cohort study: The HUNT Study
Scand J Public Health, 48 (8), 825-831
DOI 10.1177/1403494819885234, PubMed 31825300
Measuring physical performance in highly active older adults: associations with age and gender?
Aging Clin Exp Res, 32 (2), 229-237
DOI 10.1007/s40520-019-01190-x, PubMed 30977080
Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study
Lancet Public Health, 4 (11), e565-e574
DOI 10.1016/S2468-2667(19)30183-5, PubMed 31677775
Mortality in older adults with frequent alcohol consumption and use of drugs with addiction potential - The Nord Trøndelag Health Study 2006-2008 (HUNT3), Norway, a population-based study
PLoS One, 14 (4), e0214813
DOI 10.1371/journal.pone.0214813, PubMed 30990815
Factors associated with alcohol consumption and prescribed drugs with addiction potential among older women and men - the Nord-Trøndelag health study (HUNT2 and HUNT3), Norway, a population-based longitudinal study
BMC Geriatr, 19 (1), 113
DOI 10.1186/s12877-019-1114-2, PubMed 30999872
Prescribing of antipsychotic drugs to older patients living at home 2006–18
Tidsskr Nor Laegeforen, 139 (16)
DOI 10.4045/tidsskr.19.0233, PubMed 31686488
Cost analysis of day care centres in Norway
PLoS One, 14 (8), e0219568
DOI 10.1371/journal.pone.0219568, PubMed 31393890
Can screening tools for potentially inappropriate prescriptions in older adults prevent serious adverse drug events?
Eur J Clin Pharmacol, 75 (5), 627-637
DOI 10.1007/s00228-019-02624-1, PubMed 30662995
Higher Vitamin D Levels Are Associated with Better Attentional Functions: Data from the NorCog Register
J Nutr Health Aging, 23 (8), 725-731
DOI 10.1007/s12603-019-1220-z, PubMed 31560030