Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Geriatric Medicine

31 publications found

Bakkane Bendixen A, Engedal K, Selbaek G, Benth JŠ, Hartberg CB (2019)
Anxiety symptom levels are persistent in older adults with a mental disorder: A 33-month follow-up study
Int J Geriatr Psychiatry, 34 (4), 601-608
DOI 10.1002/gps.5058, PubMed 30609143

Bragstad LK, Bronken BA, Sveen U, Hjelle EG, Kitzmüller G, Martinsen R, Kvigne KJ, Mangset M, Kirkevold M (2019)
Implementation fidelity in a complex intervention promoting psychosocial well-being following stroke: an explanatory sequential mixed methods study
BMC Med Res Methodol, 19 (1), 59
DOI 10.1186/s12874-019-0694-z, PubMed 30876403

Evensen S, Saltvedt I, Ranhoff AH, Myrstad M, Myrstad C, Mellingsaeter M, Wang-Hansen MS, Neerland BE (2019)
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr. Nor. Laegeforen., 139 (6), 517-520

Evensen S, Saltvedt I, Ranhoff AH, Myrstad M, Myrstad C, Mellingsæter M, Wang-Hansen MS, Neerland BE (2019)
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0578, PubMed 30917648

Flak MM, Hol HR, Hernes SS, Chang L, Engvig A, Bjuland KJ, Pripp A, Madsen BO, Knapskog AB, Ulstein I, Lona T, Skranes J, Løhaugen GCC (2019)
Adaptive Computerized Working Memory Training in Patients With Mild Cognitive Impairment. A Randomized Double-Blind Active Controlled Trial
Front Psychol, 10, 807
DOI 10.3389/fpsyg.2019.00807, PubMed 31031677

Fluge Ø, Rekeland IG, Lien K, Thürmer H, Borchgrevink PC, Schäfer C, Sørland K, Aßmus J, Ktoridou-Valen I, Herder I, Gotaas ME, Kvammen Ø, Baranowska KA, Bohnen LMLJ, Martinsen SS, Lonar AE, Solvang AH, Gya AES, Bruland O, Risa K, Alme K, Dahl O, Mella O (2019)
B-Lymphocyte Depletion in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Ann Intern Med (in press)
DOI 10.7326/M18-1451, PubMed 30934066

Fog AF, Straand J, Engedal K, Blix HS (2019)
Drug use differs by care level. A cross-sectional comparison between older people living at home or in a nursing home in Oslo, Norway
BMC Geriatr, 19 (1), 49
DOI 10.1186/s12877-019-1064-8, PubMed 30782115

Fure B (2019)
Acute delirium
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.19.0174, PubMed 30917644

Gebremariam MK, Arah OA, Bergh IH, Andersen LF, Ommundsen Y, Totland TH, Bjelland M, Grydeland M, Lien N (2019)
Gender-specific mediators of the association between parental education and adiposity among adolescents: the HEIA study
Sci Rep, 9 (1), 7282
DOI 10.1038/s41598-019-43604-w, PubMed 31086277

Hagberg G, Fure B, Sandset EC, Thommessen B, Ihle-Hansen H, Øksengård AR, Nygård S, Wyller TB, Ihle-Hansen H (2019)
Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study
Vasc Health Risk Manag, 15, 11-18
DOI 10.2147/VHRM.S191873, PubMed 30799926

Hjelle EG, Bragstad LK, Zucknick M, Kirkevold M, Thommessen B, Sveen U (2019)
The General Health Questionnaire-28 (GHQ-28) as an outcome measurement in a randomized controlled trial in a Norwegian stroke population
BMC Psychol, 7 (1), 18
DOI 10.1186/s40359-019-0293-0, PubMed 30902115

Hov KR, Neerland BE, Undseth Ø, Wyller VBB, MacLullich AMJ, Qvigstad E, Skovlund E, Wyller TB (2019)
The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial
Int J Geriatr Psychiatry (in press)
DOI 10.1002/gps.5098, PubMed 30901487

Hvidsten L, Engedal K, Selbaek G, Wyller TB, Šaltytė Benth J, Bruvik F, Kersten H (2019)
Quality of life of family carers of persons with young-onset compared to late-onset dementia
Aging Ment Health, 1-8 (in press)
DOI 10.1080/13607863.2019.1617245, PubMed 31106576

Hvidsten L, Engedal K, Selbæk G, Wyller TB, Benth JŠ, Kersten H (2019)
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study
J Alzheimers Dis, 67 (1), 197-210
DOI 10.3233/JAD-180479, PubMed 30530973

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256

Kimura NRS, Neto JPS, Santos RL, Baptista MAT, Portugal G, Johannessen A, Barca ML, Engedal K, Laks J, Rodrigues VM, Dourado MCN (2019)
Resilience in Carers of People With Young-Onset Alzheimer Disease
J Geriatr Psychiatry Neurol, 32 (2), 59-67
DOI 10.1177/0891988718824039, PubMed 30651027

Kirkhus L, Šaltytė Benth J, Grønberg BH, Hjermstad MJ, Rostoft S, Harneshaug M, Selbæk G, Wyller TB, Jordhøy MS (2019)
Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study
Palliat Med, 33 (3), 312-322
DOI 10.1177/0269216319825972, PubMed 30712456

Kitzmüller G, Mangset M, Evju AS, Angel S, Aadal L, Martinsen R, Bronken BA, Kvigne K, Bragstad LK, Hjelle EG, Sveen U, Kirkevold M (2019)
Finding the Way Forward: The Lived Experience of People With Stroke After Participation in a Complex Psychosocial Intervention
Qual Health Res, 1049732319833366 (in press)
DOI 10.1177/1049732319833366, PubMed 30862270

Knapskog AB, Braekhus A, Engedal K (2019)
The Effect of Changing the Amyloid β42 Cut-off of Cerebrospinal Fluid Biomarkers on Alzheimer Disease Diagnosis in a Memory Clinic Population in Norway
Alzheimer Dis Assoc Disord, 33 (1), 72-74
DOI 10.1097/WAD.0000000000000268, PubMed 30106756

Langhammer B, Sagbakken M, Kvaal K, Ulstein I, Nåden D, Rognstad MK (2019)
Music Therapy and Physical Activity to Ease Anxiety, Restlessness, Irritability, and Aggression in Individuals With Dementia With Signs of Frontotemporal Lobe Degeneration
J Psychosoc Nurs Ment Health Serv, 57 (5), 29-37
DOI 10.3928/02793695-20190124-02, PubMed 30753735

Levy I, Attias S, Gavrieli S, Oliven R, Neerland BE, Devlin JW, Ben-Arye E, Greenberg D, Schiff E (2019)
The study protocol for a randomized, controlled trial of acupuncture versus a sham procedure versus standard care alone for the treatment of delirium in acutely hospitalized older adults with a medical illness
Maturitas, 124, 72-80
DOI 10.1016/j.maturitas.2019.03.001, PubMed 31097183

Marques MJ, Woods B, Hopper L, Jelley H, Irving K, Kerpershoek L, Meyer G, Bieber A, Stephan A, Sköldunger A, Sjölund BM, Selbaek G, Rosvik J, Zanetti O, Portolani E, de Vugt M, Verhey F, Gonçalves-Pereira M, Actifcare Consortium (2019)
Relationship quality and sense of coherence in dementia: Results of a European cohort study
Int J Geriatr Psychiatry, 34 (5), 745-755
DOI 10.1002/gps.5082, PubMed 30729572

Mehlum MH, Liestøl K, Wyller TB, Hua TA, Rostrup M, Berge E (2019)
Blood pressure variability in hypertensive patients with atrial fibrillation in the VALUE trial
Blood Press, 28 (2), 77-83
DOI 10.1080/08037051.2018.1524707, PubMed 30614275

Neerland BE, Wyller TB, Wyller VBB (2019)
Autonomic cardiovascular control in older patients with acute infection and delirium: a pilot study of orthostatic stress responses
BMC Geriatr, 19 (1), 23
DOI 10.1186/s12877-019-1035-0, PubMed 30683068

Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt I et al. (2019)
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Sci Rep, 9 (1), 7013
DOI 10.1038/s41598-019-43458-2, PubMed 31065058

Røsvik J, Michelet M, Engedal K, Bieber A, Broda A, Gonçalves-Pereira M, Hopper L, Irving K, Jelley H, Kerpershoek L, Meyer G, Marques MJ, Portolani E, Sjölund BM, Sköldunger A, Stephan A, Verhey F, de Vugt M, Woods B, Wolfs C, Zanetti O, Selbaek G (2019)
Interventions to enhance access to and utilization of formal community care services for home dwelling persons with dementia and their informal carers. A scoping review
Aging Ment Health, 1-12 (in press)
DOI 10.1080/13607863.2018.1523876, PubMed 30663890

Strand EB, Mengshoel AM, Sandvik L, Helland IB, Abraham S, Nes LS (2019)
Pain is associated with reduced quality of life and functional status in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Scand J Pain, 19 (1), 61-72
DOI 10.1515/sjpain-2018-0095, PubMed 30325738

Tangen GG, Robinson HS (2019)
Measuring physical performance in highly active older adults: associations with age and gender?
Aging Clin Exp Res (in press)
DOI 10.1007/s40520-019-01190-x, PubMed 30977080

Tevik K, Selbæk G, Engedal K, Seim A, Krokstad S, Helvik AS (2019)
Mortality in older adults with frequent alcohol consumption and use of drugs with addiction potential - The Nord Trøndelag Health Study 2006-2008 (HUNT3), Norway, a population-based study
PLoS One, 14 (4), e0214813
DOI 10.1371/journal.pone.0214813, PubMed 30990815

Tevik K, Selbæk G, Engedal K, Seim A, Krokstad S, Helvik AS (2019)
Factors associated with alcohol consumption and prescribed drugs with addiction potential among older women and men - the Nord-Trøndelag health study (HUNT2 and HUNT3), Norway, a population-based longitudinal study
BMC Geriatr, 19 (1), 113
DOI 10.1186/s12877-019-1114-2, PubMed 30999872

Wang-Hansen MS, Wyller TB, Hvidsten LT, Kersten H (2019)
Can screening tools for potentially inappropriate prescriptions in older adults prevent serious adverse drug events?
Eur J Clin Pharmacol, 75 (5), 627-637
DOI 10.1007/s00228-019-02624-1, PubMed 30662995

 
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