Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

Click here to see hierarchical division and subunit overview

Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Geriatric Medicine

51 publications found

Bakkane Bendixen A, Engedal K, Selbaek G, Benth JŠ, Hartberg CB (2019)
Anxiety symptom levels are persistent in older adults with a mental disorder: A 33-month follow-up study
Int J Geriatr Psychiatry, 34 (4), 601-608
DOI 10.1002/gps.5058, PubMed 30609143

Bragstad LK, Bronken BA, Sveen U, Hjelle EG, Kitzmüller G, Martinsen R, Kvigne KJ, Mangset M, Kirkevold M (2019)
Implementation fidelity in a complex intervention promoting psychosocial well-being following stroke: an explanatory sequential mixed methods study
BMC Med Res Methodol, 19 (1), 59
DOI 10.1186/s12874-019-0694-z, PubMed 30876403

Efjestad AS, Ihle-Hansen H, Hjellvik V, Engedal K, Blix HS (2019)
Drug Use before and after Initiating Treatment with Acetylcholinesterase Inhibitors
Dement Geriatr Cogn Dis Extra, 9 (1), 196-206
DOI 10.1159/000497307, PubMed 31143200

Evensen S, Saltvedt I, Lydersen S, Wyller TB, Taraldsen K, Sletvold O (2019)
Delirium motor subtypes and prognosis in hospitalized geriatric patients - A prospective observational study
J Psychosom Res, 122, 24-28
DOI 10.1016/j.jpsychores.2019.04.020, PubMed 31126407

Evensen S, Saltvedt I, Ranhoff AH, Myrstad M, Myrstad C, Mellingsaeter M, Wang-Hansen MS, Neerland BE (2019)
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr. Nor. Laegeforen., 139 (6), 517-520

Evensen S, Saltvedt I, Ranhoff AH, Myrstad M, Myrstad C, Mellingsæter M, Wang-Hansen MS, Neerland BE (2019)
Delirium and cognitive impairment among older patients in Norwegian emergency departments
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.18.0578, PubMed 30917648

Flak MM, Hol HR, Hernes SS, Chang L, Engvig A, Bjuland KJ, Pripp A, Madsen BO, Knapskog AB, Ulstein I, Lona T, Skranes J, Løhaugen GCC (2019)
Adaptive Computerized Working Memory Training in Patients With Mild Cognitive Impairment. A Randomized Double-Blind Active Controlled Trial
Front Psychol, 10, 807
DOI 10.3389/fpsyg.2019.00807, PubMed 31031677

Fluge Ø, Rekeland IG, Lien K, Thürmer H, Borchgrevink PC, Schäfer C, Sørland K, Aßmus J, Ktoridou-Valen I, Herder I, Gotaas ME, Kvammen Ø, Baranowska KA, Bohnen LMLJ, Martinsen SS, Lonar AE, Solvang AH, Gya AES, Bruland O, Risa K, Alme K, Dahl O, Mella O (2019)
B-Lymphocyte Depletion in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Ann Intern Med, 170 (9), 585-+
DOI 10.7326/M18-1451, PubMed 30934066

Fog AF, Straand J, Engedal K, Blix HS (2019)
Drug use differs by care level. A cross-sectional comparison between older people living at home or in a nursing home in Oslo, Norway
BMC Geriatr, 19 (1), 49
DOI 10.1186/s12877-019-1064-8, PubMed 30782115

Fure B (2019)
Acute delirium
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.19.0174, PubMed 30917644

Gebremariam MK, Arah OA, Bergh IH, Andersen LF, Ommundsen Y, Totland TH, Bjelland M, Grydeland M, Lien N (2019)
Gender-specific mediators of the association between parental education and adiposity among adolescents: the HEIA study
Sci Rep, 9 (1), 7282
DOI 10.1038/s41598-019-43604-w, PubMed 31086277

Gunnes M, Indredavik B, Langhammer B, Lydersen S, Ihle-Hansen H, Dahl AE, Askim T, LAST Collaboration group (2019)
Associations between adherence to the physical activity and exercise program applied in the LAST-study (Life After STroke) and functional recovery after stroke
Arch Phys Med Rehabil (in press)
DOI 10.1016/j.apmr.2019.04.023, PubMed 31374191

Hagberg G, Fure B, Sandset EC, Thommessen B, Ihle-Hansen H, Øksengård AR, Nygård S, Wyller TB, Ihle-Hansen H (2019)
Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study
Vasc Health Risk Manag, 15, 11-18
DOI 10.2147/VHRM.S191873, PubMed 30799926

Halse I, Bjørkløf GH, Engedal K, Rokstad AMM, Persson K, Eldholm RS, Selbaek G, Barca ML (2019)
Applicability of the locus of control of behaviour scale for people with dementia
Aging Ment Health, 1-6 (in press)
DOI 10.1080/13607863.2019.1652244, PubMed 31402698

Hamaker ME, van Huis-Tanja LH, Rostoft S (2019)
Optimizing the geriatrician's contribution to cancer care for older patients
J Geriatr Oncol (in press)
DOI 10.1016/j.jgo.2019.06.018, PubMed 31285173

Hjelle EG, Bragstad LK, Kirkevold M, Zucknick M, Bronken BA, Martinsen R, Kvigne KJ, Kitzmüller G, Mangset M, Thommessen B, Sveen U (2019)
Effect of a dialogue-based intervention on psychosocial well-being 6 months after stroke in Norway: A randomized controlled trial
J Rehabil Med (in press)
DOI 10.2340/16501977-2585, PubMed 31411337

Hjelle EG, Bragstad LK, Zucknick M, Kirkevold M, Thommessen B, Sveen U (2019)
The General Health Questionnaire-28 (GHQ-28) as an outcome measurement in a randomized controlled trial in a Norwegian stroke population
BMC Psychol, 7 (1), 18
DOI 10.1186/s40359-019-0293-0, PubMed 30902115

Hov KR, Neerland BE, Undseth Ø, Wyller VBB, MacLullich AMJ, Qvigstad E, Skovlund E, Wyller TB (2019)
The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial
Int J Geriatr Psychiatry, 34 (7), 974-981
DOI 10.1002/gps.5098, PubMed 30901487

Hvidsten L, Engedal K, Selbæk G, Wyller TB, Benth JŠ, Kersten H (2019)
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study
J Alzheimers Dis, 67 (1), 197-210
DOI 10.3233/JAD-180479, PubMed 30530973

Hvidsten L, Engedal K, Selbæk G, Wyller TB, Šaltytė Benth J, Kersten H (2019)
Quality of life of family carers of persons with young-onset dementia: A Nordic two-year observational multicenter study
PLoS One, 14 (7), e0219859
DOI 10.1371/journal.pone.0219859, PubMed 31323066

Ihle-Hansen H, Vigen T, Berge T, Hagberg G, Engedal K, Rønning OM, Thommessen B, Lyngbakken MN, Nygård S, Røsjø H, Tveit A, Ihle-Hansen H (2019)
Carotid Atherosclerosis and Cognitive Function in a General Population Aged 63-65 Years: Data from the Akershus Cardiac Examination (ACE) 1950 Study
J Alzheimers Dis (in press)
DOI 10.3233/JAD-190327, PubMed 31306128

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256

Kimura NRS, Neto JPS, Santos RL, Baptista MAT, Portugal G, Johannessen A, Barca ML, Engedal K, Laks J, Rodrigues VM, Dourado MCN (2019)
Resilience in Carers of People With Young-Onset Alzheimer Disease
J Geriatr Psychiatry Neurol, 32 (2), 59-67
DOI 10.1177/0891988718824039, PubMed 30651027

Kirkhus L, Šaltytė Benth J, Grønberg BH, Hjermstad MJ, Rostoft S, Harneshaug M, Selbæk G, Wyller TB, Jordhøy MS (2019)
Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study
Palliat Med, 33 (3), 312-322
DOI 10.1177/0269216319825972, PubMed 30712456

Kitzmüller G, Mangset M, Evju AS, Angel S, Aadal L, Martinsen R, Bronken BA, Kvigne K, Bragstad LK, Hjelle EG, Sveen U, Kirkevold M (2019)
Finding the Way Forward: The Lived Experience of People With Stroke After Participation in a Complex Psychosocial Intervention
Qual Health Res, 1049732319833366 (in press)
DOI 10.1177/1049732319833366, PubMed 30862270

Knapskog AB, Braekhus A, Engedal K (2019)
The Effect of Changing the Amyloid β42 Cut-off of Cerebrospinal Fluid Biomarkers on Alzheimer Disease Diagnosis in a Memory Clinic Population in Norway
Alzheimer Dis Assoc Disord, 33 (1), 72-74
DOI 10.1097/WAD.0000000000000268, PubMed 30106756

Langhammer B, Ada L, Gunnes M, Ihle-Hansen H, Indredavik B, Askim T (2019)
A physical activity program is no more effective than standard care at maintaining upper limb activity in community-dwelling people with stroke: secondary outcomes from a randomized trial
Clin Rehabil, 269215519856048 (in press)
DOI 10.1177/0269215519856048, PubMed 31198048

Langhammer B, Sagbakken M, Kvaal K, Ulstein I, Nåden D, Rognstad MK (2019)
Music Therapy and Physical Activity to Ease Anxiety, Restlessness, Irritability, and Aggression in Individuals With Dementia With Signs of Frontotemporal Lobe Degeneration
J Psychosoc Nurs Ment Health Serv, 57 (5), 29-37
DOI 10.3928/02793695-20190124-02, PubMed 30753735

Lea M, Mowe M, Mathiesen L, Kvernrød K, Skovlund E, Molden E (2019)
Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward
PLoS One, 14 (7), e0220071
DOI 10.1371/journal.pone.0220071, PubMed 31329634

Levy I, Attias S, Gavrieli S, Oliven R, Neerland BE, Devlin JW, Ben-Arye E, Greenberg D, Schiff E (2019)
The study protocol for a randomized, controlled trial of acupuncture versus a sham procedure versus standard care alone for the treatment of delirium in acutely hospitalized older adults with a medical illness
Maturitas, 124, 72-80
DOI 10.1016/j.maturitas.2019.03.001, PubMed 31097183

Lien K, Johansen B, Veierød MB, Haslestad AS, Bøhn SK, Melsom MN, Kardel KR, Iversen PO (2019)
Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome
Physiol Rep, 7 (11), e14138
DOI 10.14814/phy2.14138, PubMed 31161646

Marques MJ, Woods B, Hopper L, Jelley H, Irving K, Kerpershoek L, Meyer G, Bieber A, Stephan A, Sköldunger A, Sjölund BM, Selbaek G, Rosvik J, Zanetti O, Portolani E, de Vugt M, Verhey F, Gonçalves-Pereira M, Actifcare Consortium (2019)
Relationship quality and sense of coherence in dementia: Results of a European cohort study
Int J Geriatr Psychiatry, 34 (5), 745-755
DOI 10.1002/gps.5082, PubMed 30729572

Mehlum MH, Liestøl K, Wyller TB, Hua TA, Rostrup M, Berge E (2019)
Blood pressure variability in hypertensive patients with atrial fibrillation in the VALUE trial
Blood Press, 28 (2), 77-83
DOI 10.1080/08037051.2018.1524707, PubMed 30614275

Musaeus CS, Engedal K, Høgh P, Jelic V, Mørup M, Naik M, Oeksengaard AR, Snaedal J, Wahlund LO, Waldemar G, Andersen BB (2019)
Oscillatory connectivity as a diagnostic marker of dementia due to Alzheimer's disease
Clin Neurophysiol, 130 (10), 1889-1899 (in press)
DOI 10.1016/j.clinph.2019.07.016, PubMed 31408790

Müller EG, Edwin TH, Stokke C, Navelsaker SS, Babovic A, Bogdanovic N, Knapskog AB, Revheim ME (2019)
Amyloid-β PET-Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic
PLoS One, 14 (8), e0221365
DOI 10.1371/journal.pone.0221365, PubMed 31430334

Myrstad M, Watne LO, Johnsen NT, Bors-Lind E, Neerland BE (2019)
Delirium screening in an acute geriatric ward by nurses using 4AT: results from a quality improvement project
Eur. Geriatr. Med., 10 (4), 667-671

Neerland BE, Neufeld KJ, Slooter AJC (2019)
Pharmacological Management of Delirium
JAMA Psychiatry (in press)
DOI 10.1001/jamapsychiatry.2019.1513, PubMed 31268505

Neerland BE, Wyller TB, Wyller VBB (2019)
Autonomic cardiovascular control in older patients with acute infection and delirium: a pilot study of orthostatic stress responses
BMC Geriatr, 19 (1), 23
DOI 10.1186/s12877-019-1035-0, PubMed 30683068

Nicolaisen M, Strand BH, Thorsen K (2019)
Aging With a Physical Disability, Duration of Disability, and Life Satisfaction: A 5-Year Longitudinal Study Among People Aged 40 to 79 Years
Int J Aging Hum Dev, 91415019857061 (in press)
DOI 10.1177/0091415019857061, PubMed 31237142

Ratajczak-Tretel B, Lambert AT, Johansen H, Halvorsen B, Bjerkeli V, Russell D, Sandset EC, Ihle-Hansen H, Eriksen E, Næss H, Novotny V, Khanevski AN, Truelsen TC, Idicula T, Ægidius KL, Tobro H, Krogseth SB, Ihle-Hansen H, Hagberg G, Kruuse C, Arntzen K, Bakkejord GK, Villseth M, Nakstad I, Eldøen G et al. (2019)
Atrial fibrillation in cryptogenic stroke and transient ischaemic attack - The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Rationale and design
Eur Stroke J, 4 (2), 172-180
DOI 10.1177/2396987319837089, PubMed 31259265

Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB, Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt I et al. (2019)
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Sci Rep, 9 (1), 7013
DOI 10.1038/s41598-019-43458-2, PubMed 31065058

Rostoft S, Hamaker ME (2019)
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of the elderly in the perioperative period
Eur J Surg Oncol (in press)
DOI 10.1016/j.ejso.2019.07.027, PubMed 31378416

Røsvik J, Michelet M, Engedal K, Bieber A, Broda A, Gonçalves-Pereira M, Hopper L, Irving K, Jelley H, Kerpershoek L, Meyer G, Marques MJ, Portolani E, Sjölund BM, Sköldunger A, Stephan A, Verhey F, de Vugt M, Woods B, Wolfs C, Zanetti O, Selbaek G (2019)
Interventions to enhance access to and utilization of formal community care services for home dwelling persons with dementia and their informal carers. A scoping review
Aging Ment Health, 1-12 (in press)
DOI 10.1080/13607863.2018.1523876, PubMed 30663890

Strand BH, Knapskog AB, Persson K, Holt Edwin T, Bjertness E, Engedal K, Selbaek G (2019)
The Loss in Expectation of Life due to Early-Onset Mild Cognitive Impairment and Early-Onset Dementia in Norway
Dement Geriatr Cogn Disord, 1-11 (in press)
DOI 10.1159/000501269, PubMed 31319412

Strand EB, Mengshoel AM, Sandvik L, Helland IB, Abraham S, Nes LS (2019)
Pain is associated with reduced quality of life and functional status in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Scand J Pain, 19 (1), 61-72
DOI 10.1515/sjpain-2018-0095, PubMed 30325738

Strandenæs MG, Lund A, Rokstad AMM (2019)
Facilitation of activities for people with dementia in day care: a qualitative study exploring the experiences of staff
J Multidiscip Healthc, 12, 503-513
DOI 10.2147/JMDH.S198024, PubMed 31308683

Tangen GG, Robinson HS (2019)
Measuring physical performance in highly active older adults: associations with age and gender?
Aging Clin Exp Res (in press)
DOI 10.1007/s40520-019-01190-x, PubMed 30977080

Tevik K, Selbæk G, Engedal K, Seim A, Krokstad S, Helvik AS (2019)
Factors associated with alcohol consumption and prescribed drugs with addiction potential among older women and men - the Nord-Trøndelag health study (HUNT2 and HUNT3), Norway, a population-based longitudinal study
BMC Geriatr, 19 (1), 113
DOI 10.1186/s12877-019-1114-2, PubMed 30999872

Tevik K, Selbæk G, Engedal K, Seim A, Krokstad S, Helvik AS (2019)
Mortality in older adults with frequent alcohol consumption and use of drugs with addiction potential - The Nord Trøndelag Health Study 2006-2008 (HUNT3), Norway, a population-based study
PLoS One, 14 (4), e0214813
DOI 10.1371/journal.pone.0214813, PubMed 30990815

Vossius C, Selbæk G, Benth JŠ, Wimo A, Engedal K, Kirkevold Ø, Rokstad AMM (2019)
Cost analysis of day care centres in Norway
PLoS One, 14 (8), e0219568
DOI 10.1371/journal.pone.0219568, PubMed 31393890

Wang-Hansen MS, Wyller TB, Hvidsten LT, Kersten H (2019)
Can screening tools for potentially inappropriate prescriptions in older adults prevent serious adverse drug events?
Eur J Clin Pharmacol, 75 (5), 627-637
DOI 10.1007/s00228-019-02624-1, PubMed 30662995

 
Page visits: 222156