Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2018 from OUS - Department of Geriatric Medicine

41 publications found

Allum W, Lordick F, Alsina M, Andritsch E, Ba-Ssalamah A, Beishon M, Braga M, Caballero C, Carneiro F, Cassinello F, Dekker JW, Delgado-Bolton R, Haustermans K, Henning G, Hutter B, Lövey J, Netíková IŠ, Obermannová R, Oberst S, Rostoft S, Saarto T, Seufferlein T, Sheth S, Wynter-Blyth V, Costa A et al. (2018)
ECCO essential requirements for quality cancer care: Oesophageal and gastric cancer
Crit Rev Oncol Hematol, 122, 179-193
DOI 10.1016/j.critrevonc.2017.12.019, PubMed 29458786

Bakkane Bendixen A, Engedal K, Selbæk G, Hartberg CB (2018)
Anxiety Symptoms in Older Adults with Depression Are Associated with Suicidality
Dement Geriatr Cogn Disord, 45 (3-4), 180-189
DOI 10.1159/000488480, PubMed 29860257

de Araujo NB, Nielsen TR, Engedal K, Barca ML, Coutinho ES, Laks J (2018)
Diagnosing dementia in lower educated older persons: validation of a Brazilian Portuguese version of the Rowland Universal Dementia Assessment Scale (RUDAS)
Braz J Psychiatr, 40 (3), 264-269
DOI 10.1590/1516-4446-2017-2284, PubMed 29451587

Eldholm RS, Barca ML, Persson K, Knapskog AB, Kersten H, Engedal K, Selbæk G, Brækhus A, Skovlund E, Saltvedt I (2018)
Progression of Alzheimer's Disease: A Longitudinal Study in Norwegian Memory Clinics
J Alzheimers Dis, 61 (3), 1221-1232
DOI 10.3233/JAD-170436, PubMed 29254085

Eldholm RS, Persson K, Barca ML, Knapskog AB, Cavallin L, Engedal K, Selbaek G, Skovlund E, Saltvedt I (2018)
Association between vascular comorbidity and progression of Alzheimer's disease: a two-year observational study in Norwegian memory clinics
BMC Geriatr, 18 (1), 120
DOI 10.1186/s12877-018-0813-4, PubMed 29788900

Estévez-López F, Castro-Marrero J, Wang X, Bakken IJ, Ivanovs A, Nacul L, Sepúlveda N, Strand EB, Pheby D, Alegre J, Scheibenbogen C, Shikova E, Lorusso L, Capelli E, Sekulic S, Lacerda E, Murovska M, European Network on ME/CFS (EUROMENE) (2018)
Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe-the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review
BMJ Open, 8 (9), e020817
DOI 10.1136/bmjopen-2017-020817, PubMed 30181183

Evensen S, Saltvedt I, Lydersen S, Wyller TB, Taraldsen K, Sletvold O (2018)
Environmental factors and risk of delirium in geriatric patients: an observational study
BMC Geriatr, 18 (1), 282
DOI 10.1186/s12877-018-0977-y, PubMed 30442109

Fjeldstad SH, Thoresen L, Mowé M, Irtun Ø (2018)
Changes in nutritional care after implementing national guidelines-a 10-year follow-up study
Eur J Clin Nutr, 72 (7), 1000-1006
DOI 10.1038/s41430-017-0050-5, PubMed 29321688

Fjell AM, Idland AV, Sala-Llonch R, Watne LO, Borza T, Brækhus A, Lona T, Zetterberg H, Blennow K, Wyller TB, Walhovd KB (2018)
Neuroinflammation and Tau Interact with Amyloid in Predicting Sleep Problems in Aging Independently of Atrophy
Cereb Cortex, 28 (8), 2775-2785
DOI 10.1093/cercor/bhx157, PubMed 28655157

Flak MM, Hol HR, Hernes SS, Chang L, Ernst T, Engvig A, Bjuland KJ, Madsen BO, Lindland EMS, Knapskog AB, Ulstein ID, Lona TEE, Skranes J, Løhaugen GCC (2018)
Cognitive Profiles and Atrophy Ratings on MRI in Senior Patients With Mild Cognitive Impairment
Front Aging Neurosci, 10, 384
DOI 10.3389/fnagi.2018.00384, PubMed 30519185

Fure B, Holte HH, Hov L, Vist GE, Kateraas LH, Indredavik B (2018)
Veldig tidlig mobilisering ved akutt hjerneslag
Tidsskr Nor Laegeforen, 138 (17)
DOI 10.4045/tidsskr.17.0924, PubMed 30378408

Godskesen TE, Petri S, Eriksson S, Halkoaho A, Mangset M, Pirinen M, Nielsen ZE (2018)
When Nursing Care and Clinical Trials Coincide: A Qualitative Study of the Views of Nordic Oncology and Hematology Nurses on Ethical Work Challenges
J Empir Res Hum Res Ethics, 13 (5), 475-485
DOI 10.1177/1556264618783555, PubMed 29998780

Handels RLH, Sköldunger A, Bieber A, Edwards RT, Gonçalves-Pereira M, Hopper L, Irving K, Jelley H, Kerpershoek L, Marques MJ, Meyer G, Michelet M, Portolani E, Røsvik J, Selbaek G, Stephan A, de Vugt M, Wolfs C, Woods B, Zanetti O, Verhey F, Wimo A, and Actifcare consortium (2018)
Quality of Life, Care Resource Use, and Costs of Dementia in 8 European Countries in a Cross-Sectional Cohort of the Actifcare Study
J Alzheimers Dis, 66 (3), 1027-1040
DOI 10.3233/JAD-180275, PubMed 30372674

Harneshaug M, Kirkhus L, Benth JŠ, Grønberg BH, Bergh S, Whist JE, Rostoft S, Jordhøy MS (2018)
Screening for frailty among older patients with cancer using blood biomarkers of inflammation
J Geriatr Oncol (in press)
DOI 10.1016/j.jgo.2018.07.003, PubMed 30049582

Hassel B, Mariussen E, Idland AV, Dahl GT, Ræder J, Frihagen F, Berg JP, Chaudhry FA, Wyller TB, Watne LO (2018)
CSF sodium at toxic levels precedes delirium in hip fracture patients
Neurotoxicology, 69, 11-16
DOI 10.1016/j.neuro.2018.08.010, PubMed 30149051

Henjum K, Quist-Paulsen E, Zetterberg H, Blennow K, Nilsson LNG, Watne LO (2018)
CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau
J Neuroinflammation, 15 (1), 304
DOI 10.1186/s12974-018-1331-1, PubMed 30390679

Hov KR, Neerland BE, Andersen AM, Undseth Ø, Wyller VB, MacLullich AMJ, Skovlund E, Qvigstad E, Wyller TB (2018)
The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses
BMC Pharmacol Toxicol, 19 (1), 29
DOI 10.1186/s40360-018-0218-1, PubMed 29884231

Hvidsten L, Engedal K, Selbæk G, Wyller TB, Bruvik F, Kersten H (2018)
Quality of Life in People with Young-Onset Alzheimer's Dementia and Frontotemporal Dementia
Dement Geriatr Cogn Disord, 45 (1-2), 91-104
DOI 10.1159/000487263, PubMed 29694972

Hvidsten L, Engedal K, Selbæk G, Wyller TB, Jūratė Šaltytė B, Kersten H (2018)
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study
J Alzheimers Dis (in press)
DOI 10.3233/JAD-180479, PubMed 30530973

Jensen HLB, Lillenes MS, Rabano A, Günther CC, Riaz T, Kalayou ST, Ulstein ID, Bøhmer T, Tønjum T (2018)
Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood
Neurosci Lett, 672, 53-58
DOI 10.1016/j.neulet.2018.02.043, PubMed 29474873

Johansson YA, Tsevis T, Bogdanovic N, Kenne Sarenmalm E (2018)
Delirium bör bedömas enhetligt och strukturerat i vården
Lakartidningen, 115
PubMed 29558009

Kimura NRS, Baptista MAT, Santos RL, Portugal MDG, Johannenssen A, Barca ML, Engedal K, Laks J, Simões JP, Rodrigues VM, Dourado MCN (2018)
Caregivers' Perspectives of Quality of Life of People With Young- and Late-Onset Alzheimer Disease
J Geriatr Psychiatry Neurol, 31 (2), 76-83
DOI 10.1177/0891988718759601, PubMed 29658428

Knapskog AB, Braekhus A, Engedal K (2018)
The Effect of Changing the Amyloid β42 Cut-off of Cerebrospinal Fluid Biomarkers on Alzheimer Disease Diagnosis in a Memory Clinic Population in Norway
Alzheimer Dis Assoc Disord (in press)
DOI 10.1097/WAD.0000000000000268, PubMed 30106756

Mehlum MH, Liestøl K, Kjeldsen SE, Berge E (2018)
Response to letters from Torp-Pedersen and colleagues and de Courson and colleagues
Eur Heart J, 39 (47), 4221
DOI 10.1093/eurheartj/ehy605, PubMed 30496492

Mehlum MH, Liestøl K, Kjeldsen SE, Julius S, Hua TA, Rothwell PM, Mancia G, Parati G, Weber MA, Berge E (2018)
Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks
Eur Heart J, 39 (24), 2243-2251
DOI 10.1093/eurheartj/ehx760, PubMed 29365085

Michelet M, Engedal K, Selbæk G, Lund A, Bjørkløf GH, Horndalsveen PO, Bergh S (2018)
The Validity of the Norwegian Version of the Cognitive Function Instrument
Dement Geriatr Cogn Disord, 46 (3-4), 217-228
DOI 10.1159/000493463, PubMed 30336471

Montroni I, Ugolini G, Saur NM, Spinelli A, Rostoft S, Millan M, Wolthuis A, Daniels IR, Hompes R, Penna M, Fürst A, Papamichael D, Desai AM, Cascinu S, Gèrard JP, Myint AS, Lemmens VEPP, Berho M, Lawler M, De Liguori Carino N, Potenti F, Nanni O, Altini M, Beets G, Rutten H et al. (2018)
Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer
Eur J Surg Oncol, 44 (11), 1685-1702
DOI 10.1016/j.ejso.2018.08.003, PubMed 30150158

Musaeus CS, Engedal K, Høgh P, Jelic V, Mørup M, Naik M, Oeksengaard AR, Snaedal J, Wahlund LO, Waldemar G, Andersen BB (2018)
EEG Theta Power Is an Early Marker of Cognitive Decline in Dementia due to Alzheimer's Disease
J Alzheimers Dis, 64 (4), 1359-1371
DOI 10.3233/JAD-180300, PubMed 29991135

Ommundsen N, Nesbakken A, Wyller TB, Skovlund E, Bakka AO, Jordhøy MS, Rostoft S (2018)
Post-discharge complications in frail older patients after surgery for colorectal cancer
Eur J Surg Oncol, 44 (10), 1542-1547
DOI 10.1016/j.ejso.2018.06.024, PubMed 30037638

Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhøy MS, Skovlund E, Rostoft S (2018)
Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial
Colorectal Dis, 20 (1), 16-25
DOI 10.1111/codi.13785, PubMed 28649755

Oppedal K, Ferreira D, Cavallin L, Lemstra AW, Ten Kate M, Padovani A, Rektorova I, Bonanni L, Wahlund LO, Engedal K, Nobili F, Kramberger M, Taylor JP, Hort J, Snædal J, Blanc F, Walker Z, Antonini A, Westman E, Aarsland D, Alzheimer's Disease Neuroimaging Initiative (2018)
A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium
Alzheimers Dement (in press)
DOI 10.1016/j.jalz.2018.09.011, PubMed 30439333

Paillaud E, Soubeyran P, Caillet P, Cudennec T, Brain E, Terret C, Etchepare F, Mourey L, Aparicio T, Pamoukdjian F, Audisio RA, Rostoft S, Hurria A, Bellera C, Mathoulin-Pélissier S, G-CODE collaborators (2018)
Multidisciplinary development of the Geriatric Core Dataset for clinical research in older patients with cancer: A French initiative with international survey
Eur J Cancer, 103, 61-68
DOI 10.1016/j.ejca.2018.07.137, PubMed 30212804

Rasmussen H, Stordal E, Rosness TA (2018)
Risk factors for frontotemporal dementia
Tidsskr Nor Laegeforen, 138 (14)
DOI 10.4045/tidsskr.17.0763, PubMed 30234270

Stephan A, Bieber A, Hopper L, Joyce R, Irving K, Zanetti O, Portolani E, Kerpershoek L, Verhey F, de Vugt M, Wolfs C, Eriksen S, Røsvik J, Marques MJ, Gonçalves-Pereira M, Sjölund BM, Jelley H, Woods B, Meyer G, Actifcare Consortium (2018)
Barriers and facilitators to the access to and use of formal dementia care: findings of a focus group study with people with dementia, informal carers and health and social care professionals in eight European countries
BMC Geriatr, 18 (1), 131
DOI 10.1186/s12877-018-0816-1, PubMed 29866102

Strand BH, Knapskog AB, Persson K, Edwin TH, Amland R, Mjørud M, Bjertness E, Engedal K, Selbæk G (2018)
Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway
PLoS One, 13 (9), e0204436
DOI 10.1371/journal.pone.0204436, PubMed 30240425

Strand EB, Mengshoel AM, Sandvik L, Helland IB, Abraham S, Nes LS (2018)
Pain is associated with reduced quality of life and functional status in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Scand J Pain (in press)
DOI 10.1515/sjpain-2018-0095, PubMed 30325738

Strøm BS, Šaltytė Benth J, Engedal K (2018)
Impact of the Sonas Programme on Communication over a Period of 24 Weeks in People with Moderate-to-Severe Dementia
Dement Geriatr Cogn Dis Extra, 8 (2), 238-247
DOI 10.1159/000489041, PubMed 30022997

Sverdrup K, Bergh S, Selbæk G, Røen I, Kirkevold Ø, Tangen GG (2018)
Mobility and cognition at admission to the nursing home - a cross-sectional study
BMC Geriatr, 18 (1), 30
DOI 10.1186/s12877-018-0724-4, PubMed 29378518

Thingstad P, Askim T, Beyer MK, Bråthen G, Ellekjær H, Ihle-Hansen H, Knapskog AB, Lydersen S, Munthe-Kaas R, Næss H, Pendlebury ST, Seljeseth YM, Saltvedt I (2018)
The Norwegian Cognitive impairment after stroke study (Nor-COAST): study protocol of a multicentre, prospective cohort study
BMC Neurol, 18 (1), 193
DOI 10.1186/s12883-018-1198-x, PubMed 30477436

Wyller TB, Gisvold SE (2018)
Kritisk sengemangel rammer de eldre
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0855, PubMed 30539610

Zanco M, Plácido J, Marinho V, Ferreira JV, Oliveira F, Monteiro-Junior RS, Barca ML, Engedal K, Laks J, Deslandes A (2018)
Spatial Navigation in the Elderly with Alzheimer's Disease: A Cross-Sectional Study
J Alzheimers Dis (in press)
DOI 10.3233/JAD-180819, PubMed 30507580

 
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